1. Four new tirucallane-type triterpenoids from Aphanamixis polystachya.
- Author
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Chen, Yan-Wu, Wu, Shi-Li, Dong, Fa-Wu, Yang, Rui, and He, Hong-Ping
- Subjects
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NITROUS oxide , *NUCLEAR magnetic resonance spectroscopy , *RESEARCH funding , *TERPENES , *PLANT stems , *THIN layer chromatography , *DESCRIPTIVE statistics , *CELL lines , *CANDIDA albicans , *MEDICINAL plants , *MOLECULAR structure , *CANDIDIASIS , *LEAVES , *INFLAMMATION , *PHARMACODYNAMICS - Abstract
Four new tirucallane-type triterpenoids, polystanins H–K (1–4), were obtained from the stems and leaves of Aphanamixis polystachya. Their structures were elucidated by analysis of the spectroscopic data and comparison with literature data. Compounds 1 and 2 showed week inhibitory effects against NO production in LPS-stimulated RAW264.7 cells. All the isolates were investigated for their antifungal activities against drug-resistant Candida albicans. [ABSTRACT FROM AUTHOR]
- Published
- 2024
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