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PURPOSE: To investigate the coverage of pit and fissure sealants in primary and middle school students of Hangzhou city, and to explore the causes of unsealing students. METHODS: An analysis of sealing rate and unsealing causes of eligible children in Hangzhou city was carried out, using 3 -year data of pit and fissure sealants program sponsored by the government. Based on the results, the validity of pit and fissure sealants as a government-sponsored public health program was evaluated. RESULTS: The sealing rate was 52.89%. The main reasons of unsealing were uneruption and incomplete eruption of teeth when the medical teams went to school for pit and fissure sealing. CONCLUSIONS: The main reason of unsealing is eruption issue, which can be controllable. Some scientific adjustments need to be made to improve the coverage, such as increasing sealing times considering the difference of teeth eruption. [ABSTRACT FROM AUTHOR]

The magnitude of the temperature structure coefficient is computed from echosonde data. The results clearly show that the magnitude of CT2 fluctuates with time. The fluctuation has a positive bias and fits the logarithmic normal distribution. The analysis of the spectra of CT2 shows that the spectrum Pf(CT2) usually follows the f-3 rule in both stable and unstable stratifications. There is a peak range of energy in the frequency range 10-3 to 3×10-3 s-1. The analysis of time-height cross sections of CT2 indicates that the distribution has a horizontally stratified structure in stable conditions, and follows the rule CT2∝ z-4/3 in unstable conditions. In addition, the variation of CT2 during a cold front passing the station and the relation between the weather system and boundary layer structure are analyzed. [ABSTRACT FROM AUTHOR]

Purpose: To investigate the clinical value of adding Jin-gu-lian (JGL) capsules into rheumatoid arthritis (RA) treatment by examining its impact on disease activity and quality of life (QoL) through a real-world study (RWS)., Patients and Methods: RWS was conducted to compare the inflammatory markers, including IgM-RF, ESR, and CRP, between RA patients treated with only Western medicine (reference group) and Western medicine plus JGL (study group) during one-year follow-up. The clinical data was acquired from the hospital information system (HIS). Telephone call-based follow-up on QoL (SF-36) and accompanying symptoms, including gastrointestinal complaints, attacks of pneumonia, herpes zoster, URTIs, UTIs, and LTBIs. Finally, the anti-rheumatic drugs given to both groups were also compared. RWS was further validated for its feasibility by performing studies with hydroxychloroquine (HCQ) treatment, which is a commonly used anti-rheumatic drug for RA with mild effect., Results: The study group failed to show a significant effect on inflammatory markers, especially on the CRP levels, indicating no additional clinical value of supplementing with JGL. Similarly, at the endpoint, no significant differences between the two groups on QoL and related symptoms were observed. Our study suggests that the patients in the study group might need more anti-rheumatic drugs to fill the treatment insufficiency, and the application ratio of NSAIDs would be significantly higher than the reference group. By conducting this study on HCQ treatment, the positive aspects of controlling disease activity and reducing NSAIDs application were found, which demonstrates the utility of performing the RWS to evaluate the effect of JGL., Conclusion: Adding JGL did not significantly improve the clinical efficacy of RA treatment by this RWS. Folk herbal prescriptions such as JGL are suggested to underwent strict clinical trials before application., Competing Interests: The authors report no conflicts of interest in this work., (© 2024 Chen et al.)

Purpose: To investigate the coverage of pit and fissure sealants in primary and middle school students of Hangzhou city, and to explore the causes of unsealing students., Methods: An analysis of sealing rate and unsealing causes of eligible children in Hangzhou city was carried out, using 3-year data of pit and fissure sealants program sponsored by the government. Based on the results, the validity of pit and fissure sealants as a government-sponsored public health program was evaluated., Results: The sealing rate was 52.89%. The main reasons of unsealing were uneruption and incomplete eruption of teeth when the medical teams went to school for pit and fissure sealing., Conclusions: The main reason of unsealing is eruption issue, which can be controllable. Some scientific adjustments need to be made to improve the coverage, such as increasing sealing times considering the difference of teeth eruption.