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Numerous studies have revealed that deep learning-based medical image classification models may exhibit bias towards specific demographic attributes, such as race, gender, and age. Existing bias mitigation methods often achieve high level of fairness at the cost of significant accuracy degradation. In response to this challenge, we propose an innovative and adaptable Soft Nearest Neighbor Loss-based channel pruning framework, which achieves fairness through channel pruning. Traditionally, channel pruning is utilized to accelerate neural network inference. However, our work demonstrates that pruning can also be a potent tool for achieving fairness. Our key insight is that different channels in a layer contribute differently to the accuracy of different groups. By selectively pruning critical channels that lead to the accuracy difference between the privileged and unprivileged groups, we can effectively improve fairness without sacrificing accuracy significantly. Experiments conducted on two skin lesion diagnosis datasets across multiple sensitive attributes validate the effectiveness of our method in achieving state-of-the-art trade-off between accuracy and fairness. Our code is available at https://github.com/Kqp1227/Sensitive-Channel-Pruning., Comment: 13 pages, 3 figures, early accepted by International Conference on Medical Image Computing and Computer-Assisted Intervention (MICCAI), 2024

Fairness has become increasingly pivotal in machine learning for high-risk applications such as machine learning in healthcare and facial recognition. However, we see the deficiency in the previous logits space constraint methods. Therefore, we propose a novel framework, Logits-MMD, that achieves the fairness condition by imposing constraints on output logits with Maximum Mean Discrepancy. Moreover, quantitative analysis and experimental results show that our framework has a better property that outperforms previous methods and achieves state-of-the-art on two facial recognition datasets and one animal dataset. Finally, we show experimental results and demonstrate that our debias approach achieves the fairness condition effectively.

In medical image diagnosis, fairness has become increasingly crucial. Without bias mitigation, deploying unfair AI would harm the interests of the underprivileged population and potentially tear society apart. Recent research addresses prediction biases in deep learning models concerning demographic groups (e.g., gender, age, and race) by utilizing demographic (sensitive attribute) information during training. However, many sensitive attributes naturally exist in dermatological disease images. If the trained model only targets fairness for a specific attribute, it remains unfair for other attributes. Moreover, training a model that can accommodate multiple sensitive attributes is impractical due to privacy concerns. To overcome this, we propose a method enabling fair predictions for sensitive attributes during the testing phase without using such information during training. Inspired by prior work highlighting the impact of feature entanglement on fairness, we enhance the model features by capturing the features related to the sensitive and target attributes and regularizing the feature entanglement between corresponding classes. This ensures that the model can only classify based on the features related to the target attribute without relying on features associated with sensitive attributes, thereby improving fairness and accuracy. Additionally, we use disease masks from the Segment Anything Model (SAM) to enhance the quality of the learned feature. Experimental results demonstrate that the proposed method can improve fairness in classification compared to state-of-the-art methods in two dermatological disease datasets.

Fairness has become increasingly pivotal in medical image recognition. However, without mitigating bias, deploying unfair medical AI systems could harm the interests of underprivileged populations. In this paper, we observe that while features extracted from the deeper layers of neural networks generally offer higher accuracy, fairness conditions deteriorate as we extract features from deeper layers. This phenomenon motivates us to extend the concept of multi-exit frameworks. Unlike existing works mainly focusing on accuracy, our multi-exit framework is fairness-oriented; the internal classifiers are trained to be more accurate and fairer, with high extensibility to apply to most existing fairness-aware frameworks. During inference, any instance with high confidence from an internal classifier is allowed to exit early. Experimental results show that the proposed framework can improve the fairness condition over the state-of-the-art in two dermatological disease datasets., Comment: MICCAI2023

Magnetic resonance imaging (MRI) is commonly used for brain tumor segmentation, which is critical for patient evaluation and treatment planning. To reduce the labor and expertise required for labeling, weakly-supervised semantic segmentation (WSSS) methods with class activation mapping (CAM) have been proposed. However, existing CAM methods suffer from low resolution due to strided convolution and pooling layers, resulting in inaccurate predictions. In this study, we propose a novel CAM method, Attentive Multiple-Exit CAM (AME-CAM), that extracts activation maps from multiple resolutions to hierarchically aggregate and improve prediction accuracy. We evaluate our method on the BraTS 2021 dataset and show that it outperforms state-of-the-art methods., Comment: arXiv admin note: text overlap with arXiv:2306.05476

Magnetic resonance imaging (MRI) is a commonly used technique for brain tumor segmentation, which is critical for evaluating patients and planning treatment. To make the labeling process less laborious and dependent on expertise, weakly-supervised semantic segmentation (WSSS) methods using class activation mapping (CAM) have been proposed. However, current CAM-based WSSS methods generate the object localization map using internal neural network information, such as gradient or trainable parameters, which can lead to suboptimal solutions. To address these issues, we propose the confidence-induced CAM (Cfd-CAM), which calculates the weight of each feature map by using the confidence of the target class. Our experiments on two brain tumor datasets show that Cfd-CAM outperforms existing state-of-the-art methods under the same level of supervision. Overall, our proposed Cfd-CAM approach improves the accuracy of brain tumor segmentation and may provide valuable insights for developing better WSSS methods for other medical imaging tasks.

Recent advances in denoising diffusion probabilistic models have shown great success in image synthesis tasks. While there are already works exploring the potential of this powerful tool in image semantic segmentation, its application in weakly supervised semantic segmentation (WSSS) remains relatively under-explored. Observing that conditional diffusion models (CDM) is capable of generating images subject to specific distributions, in this work, we utilize category-aware semantic information underlied in CDM to get the prediction mask of the target object with only image-level annotations. More specifically, we locate the desired class by approximating the derivative of the output of CDM w.r.t the input condition. Our method is different from previous diffusion model methods with guidance from an external classifier, which accumulates noises in the background during the reconstruction process. Our method outperforms state-of-the-art CAM and diffusion model methods on two public medical image segmentation datasets, which demonstrates that CDM is a promising tool in WSSS. Also, experiment shows our method is more time-efficient than existing diffusion model methods, making it practical for wider applications., Comment: MICCAI 2023

Fairness has become increasingly pivotal in facial recognition. Without bias mitigation, deploying unfair AI would harm the interest of the underprivileged population. In this paper, we observe that though the higher accuracy that features from the deeper layer of a neural networks generally offer, fairness conditions deteriorate as we extract features from deeper layers. This phenomenon motivates us to extend the concept of multi-exit framework. Unlike existing works mainly focusing on accuracy, our multi-exit framework is fairness-oriented, where the internal classifiers are trained to be more accurate and fairer. During inference, any instance with high confidence from an internal classifier is allowed to exit early. Moreover, our framework can be applied to most existing fairness-aware frameworks. Experiment results show that the proposed framework can largely improve the fairness condition over the state-of-the-art in CelebA and UTK Face datasets.

Medical report generation is a challenging task since it is time-consuming and requires expertise from experienced radiologists. The goal of medical report generation is to accurately capture and describe the image findings. Previous works pretrain their visual encoding neural networks with large datasets in different domains, which cannot learn general visual representation in the specific medical domain. In this work, we propose a medical report generation framework that uses a contrastive learning approach to pretrain the visual encoder and requires no additional meta information. In addition, we adopt lung segmentation as an augmentation method in the contrastive learning framework. This segmentation guides the network to focus on encoding the visual feature within the lung region. Experimental results show that the proposed framework improves the performance and the quality of the generated medical reports both quantitatively and qualitatively.

Medical images may contain various types of artifacts with different patterns and mixtures, which depend on many factors such as scan setting, machine condition, patients' characteristics, surrounding environment, etc. However, existing deep-learning-based artifact reduction methods are restricted by their training set with specific predetermined artifact types and patterns. As such, they have limited clinical adoption. In this paper, we introduce One-Shot medical image Artifact Reduction (OSAR), which exploits the power of deep learning but without using pre-trained general networks. Specifically, we train a light-weight image-specific artifact reduction network using data synthesized from the input image at test-time. Without requiring any prior large training data set, OSAR can work with almost any medical images that contain varying additive artifacts which are not in any existing data sets. In addition, Computed Tomography (CT) and Magnetic Resonance Imaging (MRI) are used as vehicles and show that the proposed method can reduce artifacts better than state-of-the-art both qualitatively and quantitatively using shorter test time.

Deep learning had already demonstrated its power in medical images, including denoising, classification, segmentation, etc. All these applications are proposed to automatically analyze medical images beforehand, which brings more information to radiologists during clinical assessment for accuracy improvement. Recently, many medical denoising methods had shown their significant artifact reduction result and noise removal both quantitatively and qualitatively. However, those existing methods are developed around human-vision, i.e., they are designed to minimize the noise effect that can be perceived by human eyes. In this paper, we introduce an application-guided denoising framework, which focuses on denoising for the following neural networks. In our experiments, we apply the proposed framework to different datasets, models, and use cases. Experimental results show that our proposed framework can achieve a better result than human-vision denoising network.