25 results on '"Chen Qiukan"'
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2. VZHE-039, a novel antisickling agent that prevents erythrocyte sickling under both hypoxic and anoxic conditions
3. Correction of murine hemoglobinopathies by prenatal tolerance induction and postnatal nonmyeloablative allogeneic BM transplants
4. Exploration of Structure–Activity Relationship of Aromatic Aldehydes Bearing Pyridinylmethoxy-Methyl Esters as Novel Antisickling Agents
5. 5-hydroxymethyl-2-furfural modifies intracellular sickle haemoglobin and inhibits sickling of red blood cells
6. Anti-sickling effect of MX-1520, a prodrug of vanillin: an in vivo study using rodents
7. Rational modification of vanillin derivatives to stereospecifically destabilize sickle hemoglobin polymer formation
8. A Triazole Disulfide Compound Increases the Affinity of Hemoglobin for Oxygen and Reduces the Sickling of Human Sickle Cells
9. Multi-Modal Mechanisms and Anti-Sickling of Novel Sulfated Non-Anticoagulant Low Molecular Weight Heparin in Sickle Cell Disease
10. Design, Synthesis, and Biological Evaluation of Ester and Ether Derivatives of Antisickling Agent 5-HMF for the Treatment of Sickle Cell Disease
11. SCD-101: A New Anti-Sickling Drug Reduces Pain and Fatigue and Improves Red Blood Cell Shape in Peripheral Blood of Patients with Sickle Cell Disease
12. Vzhe-039, a Novel Structurally-Enhanced Allosteric Hemoglobin Effector Inhibits Sickling of SS Erythrocytes In Vitro, and Exhibits Improved Pharmacologic Properties In Vivo
13. Design, Synthesis, and Biological Evaluation of Ester and Ether Derivatives of Antisickling Agent 5-HMF for the Treatment of Sickle Cell Disease
14. Crystallographic analysis of human hemoglobin elucidates the structural basis of the potent and dual antisickling activity of pyridyl derivatives of vanillin. Corrigendum
15. Relationships between MR transverse relaxation parameters R, R2 and R and hepatic iron content in thalassemic mice at 1.5 T and 3 T
16. New Approach for Finding Novel Antisickling Agents at the NIH NHLBI Sickle Cell Disease Reference Laboratory.
17. Various Drugs with or without an Antisickling Effect in the In Vitro Tests Showed a Strong Antisickling Effect in the In Vivo Studies in Transgenic Sickle Mice.
18. In Vitro Antisickling Effects of Novel Pyridyl Derivatives with Enhanced Potency.
19. 1/T2 and Magnetic Susceptibility Measurements in a Gerbil Cardiac Iron Overload Model
20. Finding of 8 New Therapeutic Agents by the Use of New High-Throughput Drug Screening Methods Established by the Nhlbi Sicke Cell Disease Reference Laboratory.
21. MSDD1, a Prodrug of 5-Hydroxymethyl-2-Furfural (5HMF), Prolongs the Antisickling Effect of 5HMF in Transgenic Sickle Mice.
22. Anti-sickling effect of MX-1520, a prodrug of vanillin: anin vivostudy using rodents
23. Relationships between MR transverse relaxation parameters R.
24. In VitroAntisickling Effects of Novel Pyridyl Derivatives with Enhanced Potency.
25. Mixed chimerism following in utero hematopoietic stem cell transplantation in murine models of hemoglobinopathy.
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