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20 results on '"Cheng, Chuantao"'

6. Experimental study and numerical analysis on the axial compression performance of CFRP strip reinforced round-end aluminum alloy tube concrete column.

Author

Cheng, Chuantao, Tang, Congrong, Xiong, Xin, Qiu, Qirong, Liao, Pengcheng, and Motoi, Iwanami

Subjects
*CONCRETE-filled tubes, *ALUMINUM alloys, *ALUMINUM tubes, *CONCRETE columns, *CARBON fiber-reinforced plastics, *NUMERICAL analysis
Abstract

Round-end aluminum alloy tube concrete columns had good durability and were very economical, but the low strength and elastic modulus of aluminum alloy led to the need for improvement in performance. This paper proposes carbon fiber reinforced plastic (CFRP) strip reinforced round-end aluminum alloy tube concrete (CREAC) columns and investigates their mechanical properties under axial compression loads. A total of eight specimens were tested, including seven CFRP reinforced specimens and one control specimen. The effects of the width, spacing, and number of layers of CFRP strips on the axial compression performance of CREAC under the same amount of CFRP were studied. The experimental results indicate that the main failure modes of the specimen are the buckling of round-end aluminum alloy tubes and the fracture of CFRP strips. The CFRP strip can significantly improve the ultimate bearing capacity of the specimen, with a maximum increase of 15.3% in the test range. When the amount of CFRP is the same, as the number of CFRP strips decreases, the bearing capacity and ductility deteriorate. Increasing the width and thickness of CFRP strips significantly improves ductility. On the basis of the validated finite element model, parameter analysis was conducted, and the calculation method for stability coefficients was fitted. A calculation method for axial compression bearing capacity suitable for CREAC was proposed, with a maximum error of less than 1% between the predicted results and experimental results. [ABSTRACT FROM AUTHOR]

Published
2024
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19. Inhibition of NOB1 by microRNA-330-5p overexpression represses cell growth of non-small cell lung cancer

Author

Kong, Ranran, primary, Liu, Wei, additional, Guo, Yurui, additional, Feng, Jie, additional, Cheng, Chuantao, additional, Zhang, Xinwu, additional, Ma, Yuefeng, additional, Li, Shaomin, additional, Jiang, Jiantao, additional, Zhang, Jin, additional, Qiao, Zhe, additional, Qin, Jie, additional, Lu, Teng, additional, and He, Xijing, additional

Published
2017
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20. Loss of Beclin1 Expression and Nrf2 Overexpression are Associated with Poor Survival of Patients with Non-Small Cell Lung Cancer

Author

Yu, Shuo, Cheng, Chuantao, Wang, Jia, Wang, Jing, Qu, Zhan, Ren, Hui, Li, Yang, Ning, Qian, Chen, Mingwei, and Hu, Tinghua

Abstract

Background: Nrf2 pathway and autophagy are abnormally activated in response to cellular stress in various types of human cancers. In this study, we selected Beclin1 as an enter point to discuss the relationship between Nrf2 pathway and autophagy, and defined their associations with clinic pathological features and survival of the patients. Method: NSCLC specimens were processed for immunohistochemical and qRT-PCR to analyses the expression of Beclin1 and Nrf2. Kaplan-Meier method and log-rank test were used in the survival data. Results: Beclin1 protein level was found to be significantly associated with more advanced TNM stage (P = 0.035), lymph node metastasis (P = 0.017) and distant metastasis (P = 0.005). The expression of Nrf2 protein was associated with larger tumor size (P = 0.032), more advanced TNM stage (P = 0.011), lymph node metastasis (P = 0.045) and distant metastasis (P = 0.013). Beside there was a strong inverse relationship between Beclin1 and Nrf2 expression in the NSCLC tissues. Distant metastasis, Beclin1, Nrf2, and Beclin1-/Nrf2+ expression was conformed to be independent prognostic factors of patients. Conclusion: Both Nrf2 overexpression and Beclin1 lower-expression are independent indicators of a poor prognosis in NSCLC patients.

Published
2018
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