79 results on '"Chengyu Guo"'
Search Results
2. Achieving an excellent balance of strength, plasticity, and stretch flangeability in a 1000 MPa grade TRIP-assisted bainitic ferrite steel
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Yuan Wang, Xingxia Hou, Chengyu Guo, Jiayun Zhang, Xu Wang, and Yunbo Xu
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TBF steel ,Pre-quenching process ,Hole expansion ratio ,Void formation ,Microstructure evolution ,Mining engineering. Metallurgy ,TN1-997 - Abstract
To address the requirements for safety enhancement, weight reduction, and emission reduction, a novel transformation-induced plasticity-assisted bainitic ferrite (TBF) steel was processed by involving a pre-quenching (PQ) process. This steel was designed with varying PQ temperatures to achieve different fractions of intercritical ferrite and bainite, and its influence on mechanical properties of TBF steels was thoroughly investigated through tensile tests and hole expansion tests. The results demonstrated that the introduction of high-temperature PQ treatment before heat treatment can dramatically accelerate the formation of austenite during the secondary annealing process, thereby facilitating a more sufficient bainitic transformation in the subsequent isothermal process. With the increase of PQ temperature from 750 to 900 °C, abundant intercritical ferrite was replaced by lathy bainite. In comparison with conventional specimens, the high-temperature PQ treatment could reduce the fraction of intercritical ferrite and martensite-austenite (M-A) islands, in favor of delaying the initiation of microvoid and microcrack and improving local formability. In summary, the P-900 specimen exhibited optimal comprehensive mechanical properties, with the highest yield strength of 657 MPa, ultimate tensile strength of 1081 MPa, elongation of 28.7%, and hole expansion ratio of 35.1%.
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- 2024
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3. Pre-quenching induced lath structures and enhanced TRIP effect to optimize the strength-ductility of ultrahigh-strength hot-galvanized steel
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Yu Wang, Tianyu Zhang, Yunbo Xu, Yuan Wang, and Chengyu Guo
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Hot-galvanized steel ,Pre-quenching ,QAT treatment ,Mechanical properties ,Microstructure ,Retained austenite ,Mining engineering. Metallurgy ,TN1-997 - Abstract
Compared with the conventional hot-dip galvanized steel, an optimized strength-ductility combination was obtained by the combination of continuous galvanizing line (CGL) compatible quenching and austempering (QAT) treatment and pre-quenching, i.e., “pre-quenching + CGL-QAT”. The effects of the pre-quenching on the microstructure and mechanical performance were analyzed by using dilatometry, SEM, AES-EBSD, TEM and XRD technique. Compared with QAT samples, pre-quenching could eliminate the blocky M-A islands and promote the formation of lath reversed austenite and bainite ferrite in “pre-quenching + CGL-QAT” samples. Meanwhile, a large fraction (22.7–25.8%) of lath RA were obtained, such that brittle intergranular fracture can be prevented. The lath bainite/ferrite structures and sufficient TRIP effect enhanced the strength-ductility combination with an UTS reaching 1000 MPa and TEL around 30%. The fracture mainly presents ductile fracture and results in a ductile fracture surface with large dimples. The excellent strength-ductility combination with a UTS above 980 MPa, a YS of 625 MPa, a TEL of 29.1% and a higher PSE around 30 GPa·% can be obtained, which exceeds the current commercial hot-dip galvanized steel grades.
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- 2023
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4. Enhanced stretch flangeability and crack propagation behavior of an 1100 MPa grade TRIP-aided bainitic ferrite steel
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Yuan Wang, Yunbo Xu, Yu Wang, Jiayun Zhang, Chengyu Guo, Xu Wang, Wenzhu Zhao, and Hongliang Liu
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Mechanical properties ,Stretch flangeability ,Voids formation ,Crack propagation ,TBF steel ,Fracture toughness ,Mining engineering. Metallurgy ,TN1-997 - Abstract
In order to face the challenges of lightweight, safety, and emission reduction in the automotive industry, transformation-induced plasticity aided bainitic ferrite (TBF) steel was fabricated by controlling the size and shape of bainitic ferrite and compared with quenching and partitioning (Q&P) steels. The effects of bainite transformation on the mechanical properties, microvoid formation, and crack propagation were analyzed by dilatometry measurement and microstructure characterization. At lower isothermal bainite transformation (IBT) temperature, the lathy bainitic matrix can prevent crack formation and limit the crack propagation inside its laths, in favor of improving the strength and stretch flangeability simultaneously. In addition, granular bainite, coarse martensite, and austenite (M-A) islands would increase the risk of void formation at higher IBT temperatures. These voids provided the initial sites for crack formation, which was also responsible for the reduction of the hole expansion ratio (HER). In conclusion, the outstanding properties were achieved in the T-375 samples with the HER of 33.5%, the total elongation of 16.9%, the tensile strength of 1191 MPa, and the yield strength of 934 MPa.
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- 2023
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5. PHB2 promotes colorectal cancer cell proliferation and tumorigenesis through NDUFS1-mediated oxidative phosphorylation
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Lin Ren, Li Meng, Jing Gao, Mingdian Lu, Chengyu Guo, Yunyun Li, Ziye Rong, and Yan Ye
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Cytology ,QH573-671 - Abstract
Abstract The alteration of cellular energy metabolism is a hallmark of colorectal cancer (CRC). Accumulating evidence has suggested oxidative phosphorylation (OXPHOS) is upregulated to meet the demand for energy in tumor initiation and development. However, the role of OXPHOS and its regulatory mechanism in CRC tumorigenesis and progression remain unclear. Here, we reveal that Prohibitin 2 (PHB2) expression is elevated in precancerous adenomas and CRC, which promotes cell proliferation and tumorigenesis of CRC. Additionally, knockdown of PHB2 significantly reduces mitochondrial OXPHOS levels in CRC cells. Meanwhile, NADH:ubiquinone oxidoreductase core subunit S1 (NDUFS1), as a PHB2 binding partner, is screened and identified by co-immunoprecipitation and mass spectrometry. Furthermore, PHB2 directly interacts with NDUFS1 and they co-localize in mitochondria, which facilitates NDUFS1 binding to NADH:ubiquinone oxidoreductase core subunit V1 (NDUFV1), regulating the activity of complex I. Consistently, partial inhibition of complex I activity also abrogates the increased cell proliferation induced by overexpression of PHB2 in normal human intestinal epithelial cells and CRC cells. Collectively, these results indicate that increased PHB2 directly interacts with NDUFS1 to stabilize mitochondrial complex I and enhance its activity, leading to upregulated OXPHOS levels, thereby promoting cell proliferation and tumorigenesis of CRC. Our findings provide a new perspective for understanding CRC energy metabolism, as well as novel intervention strategies for CRC therapeutics.
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- 2023
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6. Nuclear paraspeckle assembly transcript 1 promotes the podocyte injury via targeting miR-23b-3p/B-cell lymphoma-2 interacting protein 3 like axis
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Jing Wang, Junpeng Luo, Li Du, Xin Shu, Chengyu Guo, and Tanshi Li
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Podocyte injury ,adriamycin (ADR) ,nuclear paraspeckle assembly transcript 1 (NEAT1) ,microRNA (miR)-23b-3p ,B-cell lymphoma-2 (Bcl-2) interacting protein 3 like (BNIP3L) ,Diseases of the genitourinary system. Urology ,RC870-923 - Abstract
Background Given the reported effects of nuclear paraspeckle assembly transcript 1 (NEAT1) on kidney injury, a study is worth formulating to investigate whether and how NEAT1 impacts podocytes.Materials and methods A mouse podocyte injury model was established using the adriamycin (ADR)-induced mouse podocyte cell line (MPC5). The target relationships between NEAT1 and microRNA (miR)-23b-3p and between miR-23b-3p and Bcl-2 interacting protein 3 like (BNIP3L) were verified by dual-luciferase reporter assay and RNA immunoprecipitation assay. After ADR-induced MPC5 cells were transfected with NEAT1 overexpression plasmid (oe-NEAT1) or shNEAT1, the viability and apoptosis of MPC5 cells were evaluated by Cell Counting Kit-8 (CCK-8) assay and flow cytometry, respectively. The expressions of MPC5, miR-23b-3p, BNIP3L and the factors related to podocyte injury, apoptosis and epithelial-mesenchymal transition were determined using quantitative real-time polymerase chain reaction (qRT-PCR) and Western blot.Results NEAT1 was high-expressed in ADR-induced cell model. After transfection with oe-NEAT1, the expression of NEAT1, the levels of marker (Desmin) and apoptosis were promoted, while the viability and the levels of podocyte injury markers (WT1, Nephrin) were inhibited in ADR-induced cells. However, shNEAT1 generated the effects opposite to oe-NEAT1. Besides, miR-23b-3p competitively bound to NEAT1 and targeted BNIP3L. MiR-23b-3p inhibitor reversed the effect of shNEAT1, while its effect could be further offset by shBNIP3L. Furthermore, miR-23b-3p inhibitor affected mouse podocyte injury through downregulating Bcl-2 and E-cadherin levels and upregulating Cleaved-caspase-3, Bax, N-cadherin, Vimentin and Snail levels, but shBNIP3L did oppositely.Conclusion NEAT1 promotes the podocyte injury via targeting miR-23b-3p/BNIP3L axis.
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- 2022
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7. A prediction model for massive hemorrhage in trauma: a retrospective observational study
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Chengyu Guo, Minghui Gong, Lei Ji, Fei Pan, Hui Han, Chunping Li, and Tanshi Li
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Trauma ,Massive hemorrhage ,LASSO ,Prediction model ,Assisted diagnosis ,Special situations and conditions ,RC952-1245 ,Medical emergencies. Critical care. Intensive care. First aid ,RC86-88.9 - Abstract
Abstract Background Massive hemorrhage is the main cause of preventable death after trauma. This study aimed to establish prediction models for early diagnosis of massive hemorrhage in trauma. Methods Using the trauma database of Chinese PLA General Hospital, two logistic regression (LR) models were fit to predict the risk of massive hemorrhage in trauma. Sixty-two potential predictive variables, including clinical symptoms, vital signs, laboratory tests, and imaging results, were included in this study. Variable selection was done using the least absolute shrinkage and selection operator (LASSO) method. The first model was constructed based on LASSO feature selection results. The second model was constructed based on the first vital sign recordings of trauma patients after admission. Finally, a web calculator was developed for clinical use. Results A total of 2353 patients were included in this study. There were 377 (16.02%) patients with massive hemorrhage. The selected predictive variables were heart rate (OR: 1.01; 95% CI: 1.01–1.02; P
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- 2022
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8. Robust age estimation model using group‐aware contrastive learning
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Xiaoqiang Li, Chengyu Guo, Yifan Wu, Congcong Zhu, and Jide Li
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Photography ,TR1-1050 ,Computer software ,QA76.75-76.765 - Abstract
Abstract Although great efforts have been devoted to developing lightweight models for age estimation in recent works, the robustness is still unsatisfactory in unconstrained environments. This paper proposes a Group‐aware Contrastive Network (GACN), a robust lightweight model, which extracts discriminative features by leveraging contrastive learning rather than increasing model parameters. Specifically, with a carefully designed contrastive loss function, GACN minimizes intra‐class distances and maximizes inter‐class distances between different age groups in feature space. Thus, faces belonging to the same age group are pulled together, while clusters of faces from different age groups are pushed apart. Unlike existing contrastive learning methods, which are separated from the downstream tasks, GACN integrates contrastive learning into age regression and jointly optimizes them for age representation learning. This allows to achieve robust age estimation using a lightweight network that is 1/662 of the model size of VGGNet. Extensive experiments on IMDB‐WIKI, Morph II, and FG‐NET demonstrate that the proposed method has a significant improvement over the baseline model and performs comparably to existing compact and bulky methods.
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- 2022
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9. Phonetic Realizations of Metrical Structure in Tone Languages: Evidence From Chinese Dialects
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Chengyu Guo and Fei Chen
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metrical structure ,Chinese dialects ,pitch ,duration ,metrical tone sandhi ,Psychology ,BF1-990 - Abstract
In tone languages, some case studies showed that the word-level tonal representation was closely related to the underlying metrical pattern. Based on different tonal patterns in prosodic units, the metrical structures could generally be divided into the left- and right-dominant types in Chinese dialects. Yet the cross-dialectal phonetic realizations (e.g., duration and pitch) between or within these two metrical structures were still unrevealed. The current study investigated the duration and pitch realizations of disyllabic prosodic words in Changsha and Chengdu dialects (the left-dominant structure), and in Fuzhou and Xiamen dialects (the right-dominant structure). Results showed that not all the duration patterns across four Chinese dialects were sensitive to different metrical structures, indicating that the duration might not be the universal cue for metrical prominence in Chinese dialects. In terms of pitch realization across all the four Chinese dialects, level tones (sometimes falling tones) generally appeared in the metrically weak unit, while underlying pitch forms appeared in the metrically strong unit. Compared with duration, pitch might be more robust for prosodic realizations of metrical structures in Chinese dialects. Furthermore, there was an interaction between duration and pitch patterns in Chinese dialects, which could shed new light on the phenomenon of “metrical tone sandhi”. Meanwhile, this study also provides some references for the judgment of the metrical stress and prosodic realizations in other Chinese dialects.
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- 2022
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10. Semantics–Prosody Stroop Effect on English Emotion Word Processing in Chinese College Students With Trait Depression
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Fei Chen, Jing Lian, Gaode Zhang, and Chengyu Guo
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semantics–prosody Stroop ,English ,emotion word processing ,trait depression ,college students ,Psychiatry ,RC435-571 - Abstract
This study explored the performance of Chinese college students with different severity of trait depression to process English emotional speech under a complete semantics–prosody Stroop effect paradigm in quiet and noisy conditions. A total of 24 college students with high-trait depression and 24 students with low-trait depression participated in this study. They were required to selectively attend to either the prosodic emotion (happy, sad) or semantic valence (positive and negative) of the English words they heard and then respond quickly. Both prosody task and semantic task were performed in quiet and noisy listening conditions. Results showed that the high-trait group reacted slower than the low-trait group in the prosody task due to their bluntness and insensitivity toward emotional processing. Besides, both groups reacted faster under the consistent situation, showing a clear congruency-induced facilitation effect and the wide existence of the Stroop effect in both tasks. Only the Stroop effect played a bigger role during emotional prosody identification in quiet condition, and the noise eliminated such an effect. For the sake of experimental design, both groups spent less time on the prosody task than the semantic task regardless of consistency in all listening conditions, indicating the friendliness of basic emotion identification and the difficulty for second language learners in face of semantic judgment. These findings suggest the unneglectable effects of college students’ mood conditions and noise outside on emotion word processing.
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- 2022
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11. Development and Validation of a Dynamic Prediction Model for Massive Hemorrhage in Trauma
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Chengyu Guo, Maolin Tian, Minghui Gong, Fei Pan, Hui Han, Chunping Li, and Tanshi Li
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Medical emergencies. Critical care. Intensive care. First aid ,RC86-88.9 - Abstract
Objectives. Early warning prediction of massive hemorrhages can greatly reduce mortality in trauma patients. This study aimed to develop and validate dynamic prediction models for massive hemorrhage in trauma patients. Methods. Based on vital signs (e.g., heart rate, respiratory rate, pulse pressure, and peripheral oxygen saturation) time-series data and the gated recurrent unit algorithm, we characterized a group of models to flexibly and dynamically predict the occurrence of massive hemorrhages in the subsequent T hours (where T = 1, 2, and 3). Models were evaluated in terms of accuracy, sensitivity, specificity, positive predictive value, negative predictive value, F1 score, and the area under the curve (AUC). Results. Results show that of the 2205 trauma patients selected for model development, a total of 265 (12.02%) had a massive hemorrhage. The AUCs of the model in the 1-h-group, 2-h-group, and 3-h-group were 0.763 (95% CI: 0.708–0.820), 0.775 (95% CI: 0.728–0.823), and 0.756 (95% CI: 0.715–0.797), respectively. Finally, the models were used in a web calculator and information system for the hospital emergency department. Conclusions. This study developed and validated a group of dynamic prediction models based on vital sign time-series data and a deep-learning algorithm to assist medical staff in the early diagnosis and dynamic prediction of a future massive hemorrhage in trauma.
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- 2022
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12. Effect of microstructure quenched around Ac3 point on the damage behavior in 0.087C–1.35Mn steel
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Chengyu Guo, Leilei Hao, Shengci Li, Yonglin Kang, and Yuguo An
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Mining engineering. Metallurgy ,TN1-997 - Abstract
The present study was aimed at microstructure quenched around Ac3 point and its effect on the damage behavior. Thermo-Calc was used to ensure the A3, while the Ac3 was identified by means of heat treatments on DIL805A thermal dilatometer, and the quenching temperatures were determined according to the above parameters. The scanning electron microscopy (SEM) and electron back scattering diffraction (EBSD) were carried out to observe the microstructure. In-situ tensile tests with SEM were performed and the development of microcracks were recorded. The results illustrated that the microstructure depends on the quenching temperature: a dual phase microstructure of martensite islands with ferrite around them is observed when the material is quenched below A3, approximately 842 ℃. Ferrite near martensite island and interface between two martensite islands with different misorientation are generally the weak spots in microstructure. When the material is quenched from austenite region around or above Ac3, approximately 880 ℃, martensite with lath submicrostructure is obtained. The location with large misorientation between two packets is usually the weak spot in microstructure and leads to increased possibility of microcracks. Keywords: Microstructure of martensite, Development of microcracks, In-situ tension
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- 2019
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13. HTSTL: Head-and-Tail Search Network With Scale-Transfer Layer for Traffic Sign Text Detection
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Xuan He, Runmin Wang, Xiumei Li, Xing Chen, Chengyu Guo, Lv Wen, Changxin Gao, and Li Liu
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Scene text detection ,multi-oriented text ,convolutional neural network ,residual network ,Electrical engineering. Electronics. Nuclear engineering ,TK1-9971 - Abstract
Although promising results have been achieved in the area of traffic sign detection, little attention has been paid to text detection on traffic signs. In fact, in today's popular driver-less automobile industry, traffic sign text which brings abundant and valuable traffic information plays an important and indispensable role. In this work, we design an effective detector for traffic sign text, whose pipeline only consists of a preprocessing module to tackle with some complex situations, a Fully Convolutional Network (FCN) in which a Scale-transfer layer is proposed to speed up the network and a simple post-processing step. Extensive experiments on the Chinese traffic sign text dataset (CTST-1600), ICDAR 2013 and MSRA-TD500 show that the proposed method has achieved the state-of-the-art results, which proves the ability of our detector on both particularity and universality applications. We collect the Chinese text-based traffic sign dataset named CTST-1600, and it can be found at https://github.com/pummi823/test/blob/master/CTST-1600.
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- 2019
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14. Extended Local Binary Patterns for Efficient and Robust Spontaneous Facial Micro-Expression Recognition
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Chengyu Guo, Jingyun Liang, Geng Zhan, Zhong Liu, Matti Pietikainen, and Li Liu
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Micro-expression recognition ,local binary pattern ,feature extraction ,Electrical engineering. Electronics. Nuclear engineering ,TK1-9971 - Abstract
Facial Micro-Expressions (MEs) are spontaneous, involuntary facial movements when a person experiences an emotion but deliberately or unconsciously attempts to conceal his or her genuine emotions. Recently, ME recognition has attracted increasing attention due to its potential applications such as clinical diagnosis, business negotiation, interrogations, and security. However, it is expensive to build large scale ME datasets, mainly due to the difficulty of inducing spontaneous MEs. This limits the application of deep learning techniques which require lots of training data. In this paper, we propose a simple, efficient yet robust descriptor called Extended Local Binary Patterns on Three Orthogonal Planes (ELBPTOP) for ME recognition. ELBPTOP consists of three complementary binary descriptors: LBPTOP and two novel ones Radial Difference LBPTOP (RDLBPTOP) and Angular Difference LBPTOP (ADLBPTOP), which explore the local second order information along the radial and angular directions contained in ME video sequences. ELBPTOP is a novel ME descriptor inspired by unique and subtle facial movements. It is computationally efficient and only marginally increases the cost of computing LBPTOP, yet is extremely effective for ME recognition. In addition, by firstly introducing Whitened Principal Component Analysis (WPCA) to ME recognition, we can further obtain more compact and discriminative feature representations, then achieve significantly computational savings. Extensive experimental evaluation on three popular spontaneous ME datasets SMIC, CASME II and SAMM show that our proposed ELBPTOP approach significantly outperforms the previous state-of-the-art on all three single evaluated datasets and achieves promising results on cross-database recognition. Our code will be made available.
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- 2019
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15. Genome-Wide Association Studies for Dynamic Plant Height and Number of Nodes on the Main Stem in Summer Sowing Soybeans
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Fangguo Chang, Chengyu Guo, Fengluan Sun, Jishun Zhang, Zili Wang, Jiejie Kong, Qingyuan He, Ripa A. Sharmin, and Tuanjie Zhao
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soybean ,genome-wide association study ,quantitative trait nucleotide ,plant height ,number of nodes on the main stem ,dynamic development ,Plant culture ,SB1-1110 - Abstract
Plant height (PH) and the number of nodes on the main stem (NN) serve as major plant architecture traits affecting soybean seed yield. Although many quantitative trait loci for the two traits have been reported, their genetic controls at different developmental stages in soybeans remain unclear. Here, 368 soybean breeding lines were genotyped using 62,423 single nucleotide polymorphism (SNP) markers and phenotyped for the two traits at three different developmental stages over two locations in order to identify their quantitative trait nucleotides (QTNs) using compressed mixed linear model (CMLM) and multi-locus random-SNP-effect mixed linear model (mrMLM) approaches. As a result, 11 and 13 QTNs were found by CMLM to be associated with PH and NN, respectively. Among these QTNs, 8, 3, and 4 for PH and 6, 6, and 8 for NN were found at the three stages, and 3 and 6 were repeatedly detected for PH and NN. In addition, 34 and 30 QTNs were found by mrMLM to be associated with PH and NN, respectively. Among these QTNs, 11, 13, and 16 for PH and 11, 15, and 8 for NN were found at the three stages. A majority of these QTNs overlapped with the previously reported loci. Moreover, one QTN within the known E2 locus for flowering time was detected for the two traits at all three stages, and another that overlapped with the Dt1 locus for stem growth habit was also identified for the two traits at the mature stage. This may explain the highly significant correlation between the two traits. Our findings provide evidence for mixed major plus polygenes inheritance for dynamic traits and an extended understanding of their genetic architecture for molecular dissection and breeding utilization in soybeans.
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- 2018
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16. ABConv: Attention Based Convolution for Automatic Modulation Recognition.
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Chengyu Guo, Shuai Han 0002, Weixiao Meng 0001, and Cheng Li 0005
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- 2024
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17. A Layered Approach for Robust Spatial Virtual Human Pose Reconstruction Using a Still Image
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Chengyu Guo, Songsong Ruan, Xiaohui Liang, and Qinping Zhao
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body part detection ,pose estimation ,spatial pose reconstruction ,deep model ,Chemical technology ,TP1-1185 - Abstract
Pedestrian detection and human pose estimation are instructive for reconstructing a three-dimensional scenario and for robot navigation, particularly when large amounts of vision data are captured using various data-recording techniques. Using an unrestricted capture scheme, which produces occlusions or breezing, the information describing each part of a human body and the relationship between each part or even different pedestrians must be present in a still image. Using this framework, a multi-layered, spatial, virtual, human pose reconstruction framework is presented in this study to recover any deficient information in planar images. In this framework, a hierarchical parts-based deep model is used to detect body parts by using the available restricted information in a still image and is then combined with spatial Markov random fields to re-estimate the accurate joint positions in the deep network. Then, the planar estimation results are mapped onto a virtual three-dimensional space using multiple constraints to recover any deficient spatial information. The proposed approach can be viewed as a general pre-processing method to guide the generation of continuous, three-dimensional motion data. The experiment results of this study are used to describe the effectiveness and usability of the proposed approach.
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- 2016
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18. Continuous Full-Body Motion Control of Virtual Human Using Sparse Wiimotes
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Chengyu Guo, Xiaohui Liang, and Jie Liu
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Electronics ,TK7800-8360 ,Electronic computers. Computer science ,QA75.5-76.95 - Abstract
Sparse sensors that recognize full-body human motion and that control the motion of virtual humans have emerged as valuable research tools in the field of human–computer interactions. Here we propose a method for motion recognition and prolonged, continuous generation of motion data based on the recognition results. The only inputs required are the directional accelerations collected by four Wii remotes, which are attached on the four limbs of a human. The extended and continuous signal sequences are separated into small segments that can be described by particular motion content. Use of a fused hidden Markov model (FHMM) during the recognition process ensures the accuracy and efficiency with which independent motion segments are recognized. A graph model enhances the capacity of classification when dealing with a signal sequence associated with a prolonged motion. During the reconstruction and generation processes, an efficient state-based motion graph generates the extended and continuous virtual human motion data, which accurately reflects variation in the movement of the actors. Our method has a strong capacity to classify types of motion upon their recognition and the control process can be applied to a range of applications involving interaction.
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- 2012
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19. The development status, risks and countermeasures of digital works NFT in the metaverse.
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Lijuan Liu, Yang Chen, Chengyu Guo, and Zixuan Chen
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- 2023
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20. Retrieval and Evaluation of Target Component Based on Ontology Knowledge.
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Lijuan Liu and Chengyu Guo
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- 2021
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21. DHA: Supervised Deep Learning to Hash with an Adaptive Loss Function.
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Jiehao Xu, Chengyu Guo, Qingjie Liu, Jie Qin, Yunhong Wang, and Li Liu 0002
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- 2019
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22. Applying Random Forest classification to diagnose autism using acoustical voice-quality parameters during lexical tone production.
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Chengyu Guo, Fei Chen, Yajie Chang, and Jinting Yan
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- 2022
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23. Coprecipitation Synthesis of Large-Pore-Volume γ-Alumina Nanofibers by Two Serial Membrane Dispersion Microreactors with a Circulating Continuous Phase
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Zhiyuan Yu, Chengyu Guo, Xinmei Pang, Yuge Shen, Mingtang Gao, Shenyuan Zhao, Yujun Wang, and Guangsheng Luo
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General Chemical Engineering ,General Chemistry ,Industrial and Manufacturing Engineering - Published
- 2023
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24. A strong bilayer appearance model for human pose estimation from a high freedom still image.
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Chengyu Guo, Songsong Ruan, and Xiaohui Liang
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- 2016
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25. Construction and application of time-effect assessment database for experiments on war-traumatized animals
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Junkang Wang, Jing Wang, Hongliang Zhang, Chengyu Guo, Yanbiao Wang, Bing Lu, Cong Feng, Fei Pan, and Tanshi Li
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Emergency Medicine ,Critical Care and Intensive Care Medicine - Published
- 2022
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26. Constructing a CoO-CuOx heterostructure for efficient electrochemical reduction of nitrate to ammonia.
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Yujun Tang, Sanchuan Liu, Chengyu Guo, Yonggang Liu, and Zhenghua Tang
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- 2023
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27. Effects of the installation parameters on the compressive performance of helix stiffened composite piles in soft clay
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Xiangjun Lin, Wei Jin, Hao Qi, Zhenqin Zhang, Wenlong Ding, and Chengyu Guo
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- 2023
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28. PHB2 Promotes Colorectal Cancer Cell Proliferation and Tumorigenesis through NDUFS1-mediated Oxidative Phosphorylation
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Lin Ren, Li Meng, Jing Gao, Mingdian Lu, Chengyu Guo, Yunyun Li, Ziye Rong, and Yan Ye
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Cancer Research ,Cellular and Molecular Neuroscience ,Immunology ,Cell Biology - Abstract
The alteration of cellular energy metabolism is a hallmark of colorectal cancer (CRC). Accumulating evidence has suggested oxidative phosphorylation (OXPHOS) is upregulated to meet the demand for energy in tumor initiation and development. However, the role of OXPHOS and its regulatory mechanism in CRC tumorigenesis and progression remain unclear. Here, we reveal that Prohibitin 2 (PHB2) expression is elevated in precancerous adenomas and CRC, which promotes cell proliferation and tumorigenesis of CRC. Additionally, knockdown of PHB2 significantly reduces mitochondrial OXPHOS levels in CRC cells. Meanwhile, NADH:ubiquinone oxidoreductase core subunit S1 (NDUFS1), as a PHB2 binding partner, is screened and identified by co-immunoprecipitation and mass spectrometry. Furthermore, PHB2 directly interacts with NDUFS1 and they co-localize in mitochondria, which facilitates NDUFS1 binding to NADH:ubiquinone oxidoreductase core subunit V1 (NDUFV1), regulating the activity of complex Ⅰ. Consistently, partial inhibition of complex Ⅰ activity also abrogates the increased cell proliferation induced by overexpression of PHB2 in normal human intestinal epithelial cells and CRC cells. Collectively, these results indicate that increased PHB2 directly interacts with NDUFS1 to stabilize mitochondrial complex Ⅰ and enhance its activity, leading to upregulated OXPHOS levels, thereby promoting cell proliferation and tumorigenesis of CRC. Our findings provide a new perspective for understanding of CRC energy metabolism, as well as novel intervention strategies for CRC therapeutics.
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- 2022
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29. Flexible editing of human motion by three-way decomposition.
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Zhiying He, Xiaohui Liang, Jian Wang, Qinping Zhao, and Chengyu Guo
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- 2014
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30. [Research on grading prediction model of traumatic hemorrhage volume based on deep learning]
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Chengyu, Guo, Youfang, Han, Minghui, Gong, Hongliang, Zhang, Junkang, Wang, Ruizhi, Zhang, Bing, Lu, Chunping, Li, and Tanshi, Li
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Machine Learning ,Deep Learning ,Swine ,Animals ,Humans ,Hemorrhage ,Wounds, Gunshot ,Retrospective Studies - Abstract
To develop a grading prediction model of traumatic hemorrhage volume based on deep learning and assist in predicting traumatic hemorrhage volume.A retrospective observational study was conducted based on the experimental data of pig gunshot wounds in the time-effect assessment database for experiments on war-traumatized animals constructed by the General Hospital of the Chinese People's Liberation Army. The hemorrhage volume data of the study population were extracted, and the animals were divided into 0-300 mL, 301-600 mL, and600 mL groups according to the hemorrhage volume. Using vital signs indexes as the predictive variables and hemorrhage volume grading as the outcome variable, trauma hemorrhage volume grading prediction models were developed based on four traditional machine learning and ten deep learning methods. Using laboratory test indexes as predictive variables and hemorrhage volume grading as outcome variables, trauma hemorrhage volume grading prediction models were developed based on the above fourteen methods. The effect of the two groups of models was evaluated by accuracy and area under the receiver operator characteristic curve (AUC), and the optimal models in the two groups were mixed to obtain hybrid model 1. Feature selection was conducted according to the genetic algorithm, and hybrid model 2 was constructed according to the best feature combination. Finally, hybrid model 2 was deployed in the animal experiment database system.Ninety-six traumatic animals in the database were enrolled, including 27 pigs in the 0-300 mL group, 40 in the 301-600 mL group, and 29 in the600 mL group. Among the fourteen models based on vital signs indexes, fully convolutional network (FCN) model was the best [accuracy: 60.0%, AUC and 95% confidence interval (95%CI) was 0.699 (0.671-0.727)]. Among the fourteen models based on laboratory test indexes, recurrent neural network (RNN) model was the best [accuracy: 68.9%, AUC (95%CI) was 0.845 (0.829-0.860)]. After mixing the FCN and RNN models, the hybrid model 1, namely RNN-FCN model was obtained, and the performance of the model was improved [accuracy: 74.2%, AUC (95%CI) was 0.847 (0.833-0.862)]. Feature selection was carried out by genetic algorithm, and the hybrid model 2, namely RNN-FCNBased on deep learning, a grading prediction model of traumatic hemorrhage volume was developed and deployed in the information system to realize the intelligent grading prediction of traumatic animal hemorrhage volume.
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- 2022
31. Viscoelastic Notch Signaling Hydrogel Induces Liver Bile Duct Organoid Growth and Morphogenesis
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Muhammad Rizwan, Christopher Ling, Chengyu Guo, Tracy Liu, Jia‐Xin Jiang, Christine E. Bear, Shinichiro Ogawa, and Molly S. Shoichet
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Biomaterials ,Liver ,Biomedical Engineering ,Pharmaceutical Science ,Hydrogels ,Bile Ducts - Abstract
Cholangiocyte organoids can be used to model liver biliary disease; however, both a defined matrix in which to emulate cholangiocyte self-assembly and the mechano-transduction pathways involved therein remain elusive. We designed a series of defined viscoelastic hyaluronan hydrogels in which to culture primary cholangiocytes and found that by mimicking the stress relaxation rate of liver tissue, we could induce cholangiocyte organoid growth and significantly increase expression of Yes-associated protein (YAP) target genes. Strikingly, inhibition of matrix metalloproteinases (MMPs) did not significantly affect organoid growth in 3D culture, suggesting that mechanical remodeling of the viscoelastic microenvironment – and not MMP-mediated degradation – is key to cholangiocyte organoid growth. By immobilizing jagged1 to the hyaluronan, stress relaxing hydrogel, self-assembled bile duct structures formed in organoid culture, indicating the synergistic effects of Notch signaling and viscoelasticity. By uncovering critical roles of hydrogel viscoelasticity, YAP signaling and Notch activation, we controlled cholangiocyte organogenesis, thereby paving the way for their use in disease modeling and/or transplantation.
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- 2022
32. Improving Document Ranking with Relevance-based Entity Embeddings
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Jingbei Li, Chengyu Guo, and Zichao Wei
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- 2022
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33. [Changes of arterial blood gas indexes of free-field primary blast lung injury of pigs and its application value]
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Junkang, Wang, Qian, Cui, Yuqing, Huang, Hongliang, Zhang, Jing, Wang, Chengyu, Guo, Cong, Feng, Fei, Pan, and Tanshi, Li
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Oxygen ,Swine ,Partial Pressure ,Animals ,Lung Injury ,Blood Gas Analysis ,Lung - Abstract
To observe the changes of arterial blood gas indexes in pigs with the free-field primary blast lung injury (PBLI) model, and to explore the value of arterial blood gas indexes in predicting moderate to severe PBLI.Nine adult healthy Landrace pigs were selected to construct the pig free-field PBLI model. Arterial blood samples were taken 15 minutes before the explosion (before injury) and 10, 30, 60, 120, and 180 minutes after the explosion (after injury). Arterial blood gas indexes and pulse oxygen saturation (SpOAs time prolonged, at each time point, pH, arterial partial pressure of oxygen (PaOThis study successfully established a large mammalian free-field PBLI model, arterial blood gas analysis is helpful for the early diagnosis of PBLI, whether SpO
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- 2022
34. Development and Validation of Dynamic Predictive Models Using Vital Signs for Trauma-associated Severe Hemorrhage: a Comparative Study
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Chengyu Guo, Minghui Gong, Qiaochu Shen, Ruolin Wang, Hongliang Zhang, Junkang Wang, Tanshi Li, and Chunping Li
- Abstract
Background: This study aimed to develop and to validate dynamic predictive models for trauma-associated severe hemorrhage based on vital signs to register early warning and dynamic prediction of severe hemorrhage in trauma patients.Methods: The MIMIC-IV cohort was collected retrospectively. The inclusion criteria were trauma patients aged ≥16 years with complete clinical data. Heart rate, respiratory rate, systolic blood pressure, diastolic blood pressure, and peripheral oxygen saturation were extracted as predictive variables. Based on logistic regression, support vector machine, random forest, adaptive boosting, gated recurrent unit, and gated recurrent unit-d, predictive models for trauma-associated severe hemorrhage were developed and validated to dynamically predict whether severe hemorrhage will occur in trauma patients in the next 1 h/2 h/3 h. This study was based on the Trauma database of the General Hospital of the People's Liberation Army for external validation. The models were developed and validated using Python 3.8.5 software. SPSS.21 software was used for statistical analysis.Results: Of the 7522 trauma patients in the MIMIC-IV cohort, 283 (3.76%) had a severe hemorrhage. The area under the curve of the gated recurrent unit-d model was the best in the 1 h (0.946±0.029), 2 h (0.940±0.032), and 3 h groups (0.943±0.034), and there was no significant difference among the three groups. In the Trauma cohort, the area under the curve of the gated recurrent unit-d model also achieved the best performance in the 1 h (0.779±0.013), 2 h (0.780±0.008), and 3 h groups (0.778±0.009), and there was no significant difference among the three groups. When comparing the gated recurrent unit-d model with the traditional scoring systems, the gated recurrent unit-d model still has advantages. Moreover, we have developed a web-based predictive system to help clinicians use our models.Conclusions: This study developed and validated dynamic predictive models for trauma-associated severe hemorrhage based on vital signs to assist pre-hospital or in-hospital emergency personnel to make decisions, and the gated recurrent unit-d model performed best.Trial registration: The MIMIC-IV database was previously de-identified and reviewed by the institutional review board (IRB) of its host organization and determined to be exempted from subsequent IRB. We obtained the administrative permissions to use the database (Certification Number: 27959316) for our research, after completing the National Institutes of Health web-based training course: Protecting Human Research Participants. We were reviewed and approved by the Ethics Committee of Chinese PLA General Hospital to use the Trauma database. The ethical batch number is S2021-466-01. Moreover, the informed consent of subjects was waived by the Ethics Committee of Chinese PLA General Hospital.
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- 2022
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35. Atypical prosodic realization by Mandarin-speaking autistic children: Evidence from tone sandhi and neutral tone
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Chengyu Guo, Fei Chen, Jinting Yan, Xiaotian Gao, and Min Zhu
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Speech and Hearing ,Linguistics and Language ,Autism Spectrum Disorder ,Phonetics ,Cognitive Neuroscience ,Humans ,Speech ,Experimental and Cognitive Psychology ,Autistic Disorder ,Child ,LPN and LVN ,Language - Abstract
Introduction Atypical prosodic features have been widely reported in autism spectrum disorder (ASD), primarily in non-tonal language speakers. Nevertheless, the prosodic realizations in autistic people who speak tonal languages were relatively understudied. This study aimed to investigate the acoustic and phonetic patterns at the word-level speech in Mandarin-speaking autistic and typically developing (TD) children at different age ranges. Methods Thirty Mandarin-speaking autistic children (15 three- to five-year-olds and 15 six- to eight-year-olds) were recruited into the ASD group. The TD group consisted of 30 age- and gender-matched children. We employed a picture-naming task to elicit the spontaneous speech production of Mandarin disyllabic words in which tone change processes occur, namely Tone 3 (T3) sandhi and neutral tone (T0). Results The phonetic analysis showed that the ASD group generally could produce typical-like T3 sandhi and T0 in terms of pitch height. However, relative to the TD group, they exhibited flatter pitch contours during T3 sandhi production. Moreover, the acoustic pitch mean of citation tones in the ASD group was also significantly higher, accompanied by more rigid pitch curves in contour tones. In addition, the atypical temporal realization in the ASD group was manifested by the longer duration of T0 and the earlier inflection position of T3. Conclusions Mandarin-speaking autistic children under eight had the phonological ability to produce context-dependent tones based on connected tonal information at the word level. Nevertheless, their phonetic prosodic realization of tone change processes was atypical. Our findings provide evidence of atypical prosody in autistic children who speak tone languages. Clinically, these findings may be attributable to underlying neural differences in autistic children.
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- 2022
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36. Effect of microstructure quenched around Ac3 point on the damage behavior in 0.087C–1.35Mn steel
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Leilei Hao, Yuguo An, Shengci Li, Yonglin Kang, and Chengyu Guo
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010302 applied physics ,Austenite ,Quenching ,lcsh:TN1-997 ,Materials science ,Misorientation ,Metals and Alloys ,02 engineering and technology ,021001 nanoscience & nanotechnology ,Microstructure ,01 natural sciences ,Surfaces, Coatings and Films ,Biomaterials ,Ferrite (iron) ,Martensite ,0103 physical sciences ,Ceramics and Composites ,Dilatometer ,Composite material ,0210 nano-technology ,lcsh:Mining engineering. Metallurgy ,Electron backscatter diffraction - Abstract
The present study was aimed at microstructure quenched around Ac3 point and its effect on the damage behavior. Thermo-Calc was used to ensure the A3, while the Ac3 was identified by means of heat treatments on DIL805A thermal dilatometer, and the quenching temperatures were determined according to the above parameters. The scanning electron microscopy (SEM) and electron back scattering diffraction (EBSD) were carried out to observe the microstructure. In-situ tensile tests with SEM were performed and the development of microcracks were recorded. The results illustrated that the microstructure depends on the quenching temperature: a dual phase microstructure of martensite islands with ferrite around them is observed when the material is quenched below A3, approximately 842 ℃. Ferrite near martensite island and interface between two martensite islands with different misorientation are generally the weak spots in microstructure. When the material is quenched from austenite region around or above Ac3, approximately 880 ℃, martensite with lath submicrostructure is obtained. The location with large misorientation between two packets is usually the weak spot in microstructure and leads to increased possibility of microcracks. Keywords: Microstructure of martensite, Development of microcracks, In-situ tension
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- 2019
37. In-situ EBSD study of deformation behaviour of 600 MPa grade dual phase steel during uniaxial tensile tests
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Yonglin Kang, Shengci Li, Leilei Hao, Yuguo An, and Chengyu Guo
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010302 applied physics ,Materials science ,Misorientation ,Dual-phase steel ,Mechanical Engineering ,02 engineering and technology ,Work hardening ,Plasticity ,021001 nanoscience & nanotechnology ,Condensed Matter Physics ,01 natural sciences ,Mechanics of Materials ,Martensite ,0103 physical sciences ,Ultimate tensile strength ,General Materials Science ,Composite material ,Deformation (engineering) ,0210 nano-technology ,Electron backscatter diffraction - Abstract
This paper studied the plastic deformation behaviour of DP600 steel subjected to uniaxial tension, by means of in-situ EBSD technique. It provides experimental evidences and detailed insight into the microstructural aspects of plastic deformation. A phase identification method based on the band slope map of EBSD was adopted to differentiate martensite from ferrite. The results show that the plastic strain localization lies mainly in the ferrite grains, fracture could usually start in ferrite grains close to hard martensite grains. With the increase of strain, average misorientation angle decreased while the fraction of LAGBs increased. Average Taylor factor for the whole microstructure became higher at high strains due to work hardening process, and plastic deformation results in soft regions with zonal distribution parallel to the loading direction. In the undeformed state, the texture orientation ( 111 ) [ 0 1 ¯ 1 ] and ( 111 ) [ 1 1 ¯ 0 ] are the major components of the γ-fibre while ( 223 ) [ 1 1 ¯ 0 ] and ( 221 ) [ 1 1 ¯ 0 ] are the main components of α-fibre. The intensity of the α-fibre slightly decreased, while the intensity of the γ-fibre increased with increasing strain. Plastic deformation occurred in some grains which were subdivided into different regions due to the activation of different slip systems. The tensile axis orientation of the grain rotated gradually to the line link − , and lattice rotation within one single grain differs from regions to regions.
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- 2019
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38. HTSTL: Head-and-Tail Search Network With Scale-Transfer Layer for Traffic Sign Text Detection
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He Xuan, Xing Chen, Li Liu, Changxin Gao, Chengyu Guo, Li Xiumei, Runmin Wang, and Lv Wen
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050210 logistics & transportation ,General Computer Science ,Artificial neural network ,residual network ,Computer science ,business.industry ,Scene text detection ,05 social sciences ,Feature extraction ,multi-oriented text ,General Engineering ,Automotive industry ,convolutional neural network ,02 engineering and technology ,computer.software_genre ,0502 economics and business ,0202 electrical engineering, electronic engineering, information engineering ,020201 artificial intelligence & image processing ,General Materials Science ,Data mining ,lcsh:Electrical engineering. Electronics. Nuclear engineering ,business ,computer ,Traffic sign ,lcsh:TK1-9971 - Abstract
Although promising results have been achieved in the area of traffic sign detection, little attention has been paid to text detection on traffic signs. In fact, in today’s popular driver-less automobile industry, traffic sign text which brings abundant and valuable traffic information plays an important and indispensable role. In this work, we design an effective detector for traffic sign text, whose pipeline only consists of a preprocessing module to tackle with some complex situations, a Fully Convolutional Network (FCN) in which a Scale-transfer layer is proposed to speed up the network and a simple post-processing step. Extensive experiments on the Chinese traffic sign text dataset (CTST-1600), ICDAR 2013 and MSRA-TD500 show that the proposed method has achieved the state-of-the-art results, which proves the ability of our detector on both particularity and universality applications. We collect the Chinese text-based traffic sign dataset named CTST-1600, and it can be found at https://github.com/pummi823/test/blob/master/CTST-1600 .
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- 2019
39. Establishment of a Gunshot Model of Junctional Femoral Artery Hemorrhage in Swine Under Ultrasonic Guidance
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Hongliang Zhang, Tanshi Li, Chengyu Guo, Junkang Wang, and Cong Feng
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medicine.medical_specialty ,Text mining ,business.industry ,medicine.artery ,medicine ,Ultrasonic sensor ,Radiology ,Femoral artery ,business - Abstract
Background: In a combat setting, uncontrolled junctional hemorrhage, which occur at the junction of the torso and appendages, constitutes a major source of potentially preventable deaths. A reliable gunshot swine model of junctional femoral artery rupture was established under ultrasonic guidance to accurately simulate field rescue conditions. Methods: Picco monitoring was instrumented for the anesthetized Landrace pigs, and the right femoral artery was located by portable ultrasound. The pistol bullet hit the right femoral artery along the direction of ultrasonic probe, resulting in the artery rupture. After 30 seconds of uncontrolled hemorrhage, ballistic was filled with Combat Gauze to stop bleeding in BT group (n=10). Combat Gauze (QuikClot) was used to stop bleeding when the mean arterial pressure (MAP) decreased by 30% in MD group (n=10). The sham-operated pigs (n=10) underwent the same anesthetic and surgical procedures, but neither shooting nor gauze filling therapy were performed. No liquid treatment was performed in the three groups throughout the experiment. Blood samples were taken 15 min before injury, then 10 min, 30 min, and 60 min after injury to determine hemodynamic, coagulation, and arterial blood gas indexes. Animals were then monitored for 180 minutes and surviving animals were killed. Results: Histologic anatomy indicated that the right femoral artery and vein were completely ruptured in all 20 swine of MD and BT groups. Eighteen pigs had associated proximal femur fractures and the other two had associated midshaft femur fractures. The entrance diameters of wound were 11.4 mm (SD=0.4), and the exits diameters were 26.4 mm (SD=5.8). The blood loss of pre-tamponade (4.97±2.47 mL/kg vs 18.26±3.47 mL/kg, PConclusion: We established a reliable gunshot model of junctional hemorrhage in swine, which had high accuracy for femoral arterial rupture under ultrasonic guidance and provided consistent and reproducible field-simulation conditions. In this junctional hemorrhage model, blood loss of 30 seconds free bleeding did not meet criteria for shock, and MAP decreased by 30% is a better choice to ensure the success of the shock model.Trial registration: Authorized by Institutional Animal Care and Use Committee in China (grant no. SC2019-06-013).
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- 2021
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40. Gunshot model of junctional femoral artery hemorrhage in swine under ultrasonic guidance
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Zhang, Hongliang, primary, Chengyu, Guo, additional, Junkang, Wang, additional, Cong, Feng, additional, and Tanshi, Li, additional
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- 2021
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41. Efficacy of a new zeolite-based hemostatic gauze in a gunshot model of junctional femoral artery hemorrhage in swine
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Jing Wang, Kaiyuan Li, Junkang Wang, Fei Pan, Heng Zhang, Junpeng Luo, Hongliang Zhang, Chengyu Guo, Cong Feng, and Tanshi Li
- Abstract
Objective This work sought to 1) establish a reliable gunshot model of junctional femoral artery rupture in swine that accurately simulates field rescue conditions, and 2) use the gunshot model to compare the efficacy and ease of application of zeolite nanometer hemostatic gauze with other hemostatic materials, Methods 36 healthy landrace swine (body weight 50 ± 5 kg) were randomly divided into three groups which were treated with Combat Gauze (CG), FeiChuang hemostatic gauze (FG), or standard medical gauze (SG). A gunshot model of femoral artery hemorrhage in landrace swine was used with portable ultrasound to accurately position the wound. After the shooting, when mean arterial pressure (MAP) of swine decreased by at least 30% for 10 seconds, wounds were pressed with standard packing (39 g) of gauze materials for 3 minutes to stop bleeding, and then bandaged with pressure. Blood samples were taken 15 min before injury, then 10 min, 30 min, and 60 min after injury to determine hemodynamic, coagulation, and arterial blood gas indexes. Wound temperatures were taken at 5 min, 10 min, 30 min, and 60 min after injury, and survival times were recorded. Results The CG (11.15 ± 3.09 ml/kg) and FG (12.19 ± 3.5 ml/kg) groups had significantly less blood loss than the SG group (16.8 ± 5.14 ml/kg) (P = 0.04; P = 0.039, respectively). After gauze packing, bleeding in CG (5.85 ± 1.17 ml/kg) and FG (5.37 ± 0.93 ml/kg) groups remained significantly lower than that of SG group (6.93 ± 1.03 ml/kg) (P = 0.011; P = 0.003, respectively). Wound temperature rose with time for all groups (p = 0.000). The wound temperatures in the FG group and the CG group were significantly higher than that of the SG group, (p = 0.004 and 0.009, respectively). Survival rates and times were not significantly different among the three groups, though the FG group had the longest average survival time (SD 204.8 s), compared with SG group (SD 177.8 s) and CG (SD 187.5 s) groups. No significant differences in hemodynamics, blood gas, and coagulation were observed among the three groups. Conclusions The gunshot model of junctional femoral arterial hemorrhage guided by ultrasound had high accuracy for femoral arterial rupture by bullet wound, and provided consistent and reproducible field-simulation conditions for comparison of hemostatic materials. Feichuang zeolite hemostatic gauze effectively controlled bleeding without excessive heat, as found in other zeolite-based products. However, improvements to application technique, such as a packing device are needed to improve operating time.
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- 2020
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42. DHA:supervised deep learning to hash with an adaptive loss function
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Chengyu Guo, Qingjie Liu, Jie Qin, Yunhong Wang, Li Liu, and Jiehao Xu
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Computer science ,business.industry ,Deep learning ,Hash function ,adaptive ,Hamming distance ,Pattern recognition ,02 engineering and technology ,010501 environmental sciences ,01 natural sciences ,Data modeling ,k-nearest neighbors algorithm ,Discriminative model ,Hashing ,0202 electrical engineering, electronic engineering, information engineering ,020201 artificial intelligence & image processing ,Binary code ,Artificial intelligence ,business ,Image retrieval ,retrieval ,0105 earth and related environmental sciences - Abstract
Hashing, which refers to the binary embedding of high-dimensional data, has been an effective solution for fast nearest neighbor retrieval in large-scale databases due to its computational and storage efficiency. Recently, deep learning to hash has been attracting increasing attention since it has shown great potential in improving retrieval quality by leveraging the strengths of deep neural networks. In this paper, we consider the problem of supervised hashing and propose an effective model (i.e., DHA), which is able to generate compact and discriminative binary codes while preserving semantic similarities of original data with an adaptive loss function. The key idea is that we scale and shift the loss function to avoid the saturation of gradients during training, and simultaneously adjust the loss to adapt to different levels of similarities of data. We evaluate the proposed DHA on three widely-used benchmarks, i.e., NUS-WIDE, CIFAR-10, and MS COCO. The state-of-the-art image retrieval performance clearly shows the effectiveness of our method in learning discriminative hash codes for nearest neighbor retrieval.
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- 2019
43. Genome-Wide Association Studies for Dynamic Plant Height and Number of Nodes on the Main Stem in Summer Sowing Soybeans
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Ripa Akter Sharmin, Fengluan Sun, Chengyu Guo, Qingyuan He, Jiejie Kong, Jishun Zhang, Zili Wang, Tuanjie Zhao, and Fangguo Chang
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0301 basic medicine ,Genetics ,genome-wide association study ,Sowing ,Locus (genetics) ,Single-nucleotide polymorphism ,Genome-wide association study ,Plant Science ,Biology ,Quantitative trait locus ,lcsh:Plant culture ,Genetic architecture ,plant height ,03 medical and health sciences ,030104 developmental biology ,dynamic development ,Polygene ,lcsh:SB1-1110 ,soybean ,quantitative trait nucleotide ,Main stem ,Original Research ,number of nodes on the main stem - Abstract
Plant height (PH) and the number of nodes on the main stem (NN) serve as major plant architecture traits affecting soybean seed yield. Although many quantitative trait loci for the two traits have been reported, their genetic controls at different developmental stages in soybeans remain unclear. Here, 368 soybean breeding lines were genotyped using 62,423 single nucleotide polymorphism (SNP) markers and phenotyped for the two traits at three different developmental stages over two locations in order to identify their quantitative trait nucleotides (QTNs) using compressed mixed linear model (CMLM) and multi-locus random-SNP-effect mixed linear model (mrMLM) approaches. As a result, 11 and 13 QTNs were found by CMLM to be associated with PH and NN, respectively. Among these QTNs, 8, 3, and 4 for PH and 6, 6, and 8 for NN were found at the three stages, and 3 and 6 were repeatedly detected for PH and NN. In addition, 34 and 30 QTNs were found by mrMLM to be associated with PH and NN, respectively. Among these QTNs, 11, 13, and 16 for PH and 11, 15, and 8 for NN were found at the three stages. A majority of these QTNs overlapped with the previously reported loci. Moreover, one QTN within the known E2 locus for flowering time was detected for the two traits at all three stages, and another that overlapped with the Dt1 locus for stem growth habit was also identified for the two traits at the mature stage. This may explain the highly significant correlation between the two traits. Our findings provide evidence for mixed major plus polygenes inheritance for dynamic traits and an extended understanding of their genetic architecture for molecular dissection and breeding utilization in soybeans.
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- 2018
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44. Modeling of Degradation Process of Reciprocating Seal Based on Gaussian Copula Function
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Chengyu Guo, Chao Zhang, and Shaoping Wang
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Reciprocating motion ,Materials science ,Function (mathematics) ,Mechanics ,Degradation process ,Seal (mechanical) - Published
- 2018
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45. The effect of low ceiling on the external combustion of the cabin fire
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Chang-yun Chen, Liang Wang, Chengyin Wei, Shichuan Su, Chengyu Guo, and Haibing Cui
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Physics::Fluid Dynamics ,Convection ,Flue gas ,Heat flux ,Convective heat transfer ,External combustion engine ,Environmental science ,Mechanics ,Physics::Chemical Physics ,Ceiling (cloud) ,Roof ,Physics::Atmospheric and Oceanic Physics ,Plume - Abstract
External combustion is a phenomenon where the flame flares out of the window and burns outside. Because of the particularity of the ship’s cabin structure, there is a great danger in the external combustion. In this paper, the numerical calculation and analysis of three kinds of low ceiling ship cabin fire are analyzed based on the large eddy numerical simulation technique. Through the analysis of temperature, flue gas velocity, heat flux density and so on, the external combustion phenomenon of fire development is calculated. The results show that when external combustion occurs, the amount of fuel escaping decreases with the roof height. The temperature above the window increases with the height of the ceiling. The heat flux density in the external combustion flame is mainly provided by radiation, and convection is only a small part; In the plume area there is a time period, in this time period, the convective heat flux density is greater than the radiation heat flux, this time with the ceiling height increases. No matter which ceiling height, the external combustion will seriously damage the structure of the ship after a certain period of time. The velocity distribution of the three roof is similar, but with the height of the ceiling, the area size is also increasing.
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- 2018
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46. The Antibacterial Activity of Natural Product Black Tea Theaflavins On Streptococcus Mutans
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Chengyu Guo, Yina Wang, Hong Li, and Zhenyi Chen
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chemistry.chemical_compound ,Natural product ,genetic structures ,chemistry ,biology ,Food science ,Antibacterial activity ,biology.organism_classification ,Streptococcus mutans ,Black tea - Abstract
Objective The aim of the study is to investigate the antibacterial effect of the black tea theaflavins (TFs) on Streptococcus mutans (S. mutans) which cause the dentin caries. Methods (1) Broth dilution method was used for the determination of minimal inhibitory concentration (MIC) and minimal bactericidal concentration (MBC). (2) Mixed bacterial suspension with three different concentrations of TFs and recorded pH values before and after anaerobic incubation. (3) Scanning electron microscopy was used for observing bacteria morphology. Results (1) The MIC and MBC were 0.5mg/ml and 1.0mg/ml respectively. (2) With the increasing concentration of TFs, the ability of bacteria to produce acid gradually decreased. (3) TFs changed the shape of S. mutans. Conclusions Theaflavins inhibits S. mutans effectively.
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- 2019
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47. Microstructure‐Based Modeling of Mechanical Properties and Deformation Behavior of DP600 Dual Phase Steel
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Chengyu Guo, Leilei Hao, Yuguo An, Shengci Li, and Yonglin Kang
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Materials science ,Dual-phase steel ,Martensite ,Materials Chemistry ,Metals and Alloys ,Uniaxial tension ,Physical and Theoretical Chemistry ,Composite material ,Deformation (meteorology) ,Condensed Matter Physics ,Microstructure - Published
- 2019
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48. Method of obtaining the constitutive relation in DP steel based on nanoindentation and finite element modeling
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Yonglin Kang, Leilei Hao, Yuguo An, Shengci Li, and Chengyu Guo
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Biomaterials ,Reverse analysis ,Materials science ,Polymers and Plastics ,business.industry ,Constitutive equation ,Metals and Alloys ,Structural engineering ,Nanoindentation ,business ,Finite element method ,Surfaces, Coatings and Films ,Electronic, Optical and Magnetic Materials - Published
- 2019
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49. Flexible editing of human motion by three-way decomposition
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Jian Wang, Zhiying He, Chengyu Guo, Qinping Zhao, and Xiaohui Liang
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Computer science ,business.industry ,Nonlinear dimensionality reduction ,Human motion ,Computer Graphics and Computer-Aided Design ,Motion (physics) ,Style (sociolinguistics) ,Generative model ,Three way ,Decomposition (computer science) ,Identity (object-oriented programming) ,Artificial intelligence ,business ,Software - Abstract
This paper proposes a new generative model for flexible editing of human motion. Different from previous work, three intuitive factors of motion, namely, content, identity and style, can be manipulated directly with the new model. With the new generative model, motion editing can be achieved in various aspects, including transferring an unknown style from an actor to another, synthesizing other styles for an unknown actor and generating a new motion with other content. Copyright © 2013 John Wiley & Sons, Ltd.
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- 2013
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50. A strong bilayer appearance model for human pose estimation from a high freedom still image
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Songsong Ruan, Xiaohui Liang, and Chengyu Guo
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Computer science ,business.industry ,Feature extraction ,ComputingMethodologies_IMAGEPROCESSINGANDCOMPUTERVISION ,Pattern recognition ,02 engineering and technology ,010501 environmental sciences ,3D pose estimation ,01 natural sciences ,Object detection ,Active appearance model ,Discriminative model ,0202 electrical engineering, electronic engineering, information engineering ,Feature descriptor ,020201 artificial intelligence & image processing ,Computer vision ,Artificial intelligence ,Image warping ,business ,Rotation (mathematics) ,Pose ,0105 earth and related environmental sciences - Abstract
Appearance model is widely used for image description and demonstrates an impressive performance in object detection. However, most appearance models can not be applied to more freedom object in still image, especially when dealt with variant objects whose shapes are modified by warping, rotation, etc. In this article, a simple but effective method to build a regional rotation-invariant feature descriptor is proposed to catch discriminative information of the variant human pose, which has a superior advantage when targets are in arbitrary orientations and slightly warping. Moreover, a mixture spatial model with visible parameters is then presented to differentiate the body structure and estimate the visible accurate position of each joint. The experiment results indicate that the proposed descriptor give near state-of-the-art performance on both handwritten digit recognition database and two public human motion databases containing athletes or pedestrians under certain different variations.
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- 2016
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