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2. Red blood cell transfusion burden in myelodysplastic syndromes ( MDS ) with ring Sideroblasts ( RS ): A retrospective multicenter study by the Groupe Francophone des Myélodysplasies ( GFM )

Author

Jouzier, Claire, primary, Cherait, Amina, additional, Cony‐Makhoul, Pascale, additional, Hamel, Jean‐François, additional, Veloso, Melanie, additional, Thepot, Sylvain, additional, Cluzeau, Thomas, additional, Stamatoullas, Aspasia, additional, Garnier, Alice, additional, Guerci‐Bresler, Agnès, additional, Dimicoli‐Salazar, Sophie, additional, Pica, Gian Matteo, additional, Cheze, Stéphane, additional, Santana, Clémence, additional, Chermat, Fatiha, additional, Fenaux, Pierre, additional, and Park, Sophie, additional

Published
2022
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3. Very Long Term Follow up a Phase II Study of Post-Remission Subcutaneous (SC) Azacitidine (AZA) in Patients with AML Post-MDS or Higher-Risk (HR) MDS

Author

Cherait, Amina, primary, Braun, Thorsten, additional, Bouabdallah, Krimo, additional, Caillot, Denis, additional, Guerci, Agnès, additional, Raffoux, Emmanuel, additional, Marolleau, Jean Pierre, additional, Pautas, Cecile, additional, Banos, Anne, additional, Himberlin, Chantal, additional, Taksin, Anne Laure, additional, Pigneux, Arnaud, additional, Thomas, Xavier, additional, Vey, Norbert, additional, Chevret, Sylvie, additional, Dombret, Herve, additional, Chermat, Fatiha, additional, Ades, Lionel, additional, Gardin, Claude, additional, and Fenaux, Pierre, additional

Published
2020
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4. Eltrombopag for myelodysplastic syndromes or chronic myelomonocytic leukaemia with no excess blasts and thrombocytopenia: a French multicentre retrospective real‐life study.

Author

Comont, Thibault, Meunier, Mathieu, Cherait, Amina, Santana, Clemence, Cluzeau, Thomas, Slama, Bohrane, Laribi, Kamel, Giraud, Jean‐Thomas, Dimicoli, Sophie, Berceanu, Ana, Le Clech, Lenaïg, Cony‐Makhoul, Pascale, Gruson, Berangere, Torregrosa, Jose, Sanhes, Laurence, Jachiet, Vincent, Azerad, Marie‐Agnes, Al Jijakli, Ahmad, Gyan, Emmanuel, and Gaudin, Clement

Subjects
CHRONIC leukemia, MYELODYSPLASTIC syndromes, ACUTE myeloid leukemia, ELTROMBOPAG, THROMBOCYTOPENIA, VENOUS thrombosis
Abstract

Summary: Despite a moderate prevalence in low‐risk myelodysplastic syndromes (MDS) and chronic myelomonocytic leukaemia (CMML), thrombocytopenia remains a risk of severe bleeding and therapeutic options are still limited. There are only a few studies with eltrombopag (ELT), a thrombopoietin receptor agonist, in those patients. In this retrospective multicentre study, ELT was used in 50 patients with MDS and 11 with CMML, with no excess of marrow blasts and platelet counts of <50 × 109/l in a 'real‐life' situation. Platelet response occurred in 47 (77%) patients. The median (range) duration of response was 8 (0–69) months. None of the eight still responders who discontinued ELT had relapsed, at a median (range) of 16 (6–23) months after ELT discontinuation. Although 36% of the patients were anti‐coagulated or anti‐aggregated only 10% of patients had Grade ≥3 bleeding events. Thrombotic events were observed in six (10%) patients, who all but one had a medical history of arterial or venous thrombosis. Progression to acute myeloid leukaemia occurred in four (7%) patients. In this first 'real‐life' study, ELT was effective and generally well tolerated in patients with MDS/CMML without excess blasts. [ABSTRACT FROM AUTHOR]

Published
2021
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5. Red Blood Cell Transfusion Burden in Myelodysplastic Syndromes (MDS) with Ring Sideroblasts (RS): A Retrospective Multicenter Study By the Groupe Francophone Des Myélodysplasies (GFM)

Author

Jouzier, Claire, Cherait, Amina, Cony-Makhoul, Pascale, Thepot, Sylvain, Cluzeau, Thomas, Stamatoulas Bastard, Aspasia, Peterlin, Pierre, Guerci Bresler, Agnes, Dimicoli-Salazar, Sophie, Pica, Gian-Matteo, Cheze, Stephane, Santana, Clémence, Chermat, Fatiha, Fenaux, Pierre, and Park, Sophie

Published
2020
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6. Treatment With Decitabine (DAC) After Azacitidine (AZA) Failure In High Risk Myelodysplastic Syndrome (MDS) and Advanced Chronic Myelomonocytic Leukemia (CMML)

Author

Braun, Thorsten, primary, Cherait, Amina, additional, Berthon, Celine, additional, Willekens, Christophe, additional, Park, Sophie, additional, Rigal, Marthe, additional, Brechignac, Sabine, additional, Harel, Stephanie, additional, Thepot, Sylvain, additional, Quesnel, Bruno, additional, Gardin, Claude, additional, Ades, Lionel, additional, and Fenaux, Pierre, additional

Published
2013
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