563 results on '"Chiba-Falek, Ornit"'
Search Results
2. Single-nucleus multi-omics of Parkinson’s disease reveals a glutamatergic neuronal subtype susceptible to gene dysregulation via alteration of transcriptional networks
3. Integrative single-nucleus multi-omics analysis prioritizes candidate cis and trans regulatory networks and their target genes in Alzheimer’s disease brains
4. Neuronal-type-specific epigenome editing to decrease SNCA expression: Implications for precision medicine in synucleinopathies
5. Identifying nootropic drug targets via large-scale cognitive GWAS and transcriptomics.
6. Pleiotropic Meta-Analysis of Cognition, Education, and Schizophrenia Differentiates Roles of Early Neurodevelopmental and Adult Synaptic Pathways.
7. Multi-Trait Analysis of GWAS and Biological Insights Into Cognition: A Response to Hill (2018)
8. Genome-wide association meta-analysis in 269,867 individuals identifies new genetic and functional links to intelligence
9. Large-Scale Cognitive GWAS Meta-Analysis Reveals Tissue-Specific Neural Expression and Potential Nootropic Drug Targets
10. Multi‐Omics Insights Into The Heterogeneity Of Depression In Alzheimer’s Disease
11. APOE‐targeted epigenome therapy for late onset Alzheimer’s disease
12. Integrative single‐nucleus multi‐omics analysis prioritizes candidate cis and trans regulatory networks and their target genes in Alzheimer’s disease brains
13. Bioinformatics pipeline to guide post‐GWAS studies in Alzheimer’s: a new catalogue of disease candidate short structural variants
14. Sex dependent glial-specific changes in the chromatin accessibility landscape in late-onset Alzheimer’s disease brains
15. Lentiviral vectors as the delivery vehicles for transduction into iPSCs
16. Contributors
17. Bioinformatics strategy to advance the interpretation of Alzheimer's disease GWAS discoveries: The roads from association to causation
18. The APOE-TOMM40 Humanized Mouse Model: Characterization of Age, Sex, and PolyT Variant Effects on Gene Expression
19. Neurogenomics
20. Gene Expression
21. The effects of the TOMM40 poly-T alleles on Alzheimer's disease phenotypes
22. Shared genetic etiology underlying Alzheimer’s disease and major depressive disorder
23. Good problems to have? Policy and societal implications of a disease-modifying therapy for presymptomatic late-onset Alzheimer’s disease
24. Genetic analysis of α-synuclein 3′ untranslated region and its corresponding microRNAs in relation to Parkinson's disease compared to dementia with Lewy bodies
25. Sex-specific effects of scavenger receptor class B type 1 (SR-BI) gene variants on serum lipid levels and hepatic gene expression
26. Expansion of the Parkinson disease-associated SNCA- Rep1 allele upregulates human α-synuclein in transgenic mouse brain
27. Expansion of the Parkinson disease-associated SNCA-Rep1 allele upregulates human alpha-synuclein in transgenic mouse brain.
28. Integrative single-nucleus multi-omics analysis prioritizes candidate cis and trans regulatory networks and their target genes in Alzheimers disease brains
29. All-in-one AAV-delivered epigenome-editing platform:proof-of-conceptand therapeutic implications for neurodegenerative disorders
30. Author Correction: Study of 300,486 individuals identifies 148 independent genetic loci influencing general cognitive function
31. Dissecting cell‐subtype specific regulatory variants and their target genes underpinning the pathogenesis of late onset Alzheimer’s disease
32. APOE ‐targeted epigenome therapy for late onset Alzheimer’s disease
33. Differential Gene Expression and DNA Methylation in the Risk of Depression in LOAD Patients
34. Clinical Trials of AD Delay of Onset: Enrichment by a Prognostic Genetic Biomarker
35. African-American TOMM40'523-APOE haplotypes are admixture of West African and Caucasian alleles
36. The cis-regulatory effect of an Alzheimer’s disease-associated poly-T locus on expression of TOMM40 and apolipoprotein E genes
37. Study of 300,486 individuals identifies 148 independent genetic loci influencing general cognitive function
38. Infection and inflammation: New perspectives on Alzheimer's disease
39. Phenotypic regional functional imaging patterns during memory encoding in mild cognitive impairment and Alzheimer's disease
40. A homopolymer polymorphism in the TOMM40 gene contributes to cognitive performance in aging
41. Polygenic Risk Score Effectively Predicts Depression Onset in Alzheimer’s Disease Based on Major Depressive Disorder Risk Variants
42. Bioinformatics pipeline to guide late‐onset Alzheimer's disease (LOAD) post‐GWAS studies: Prioritizing transcription regulatory variants within LOAD‐associated regions
43. Bioinformatics pipeline to advance the identification of transcription regulatory variants in LOAD noncoding regions
44. Polygenic Risk Score Effectively Predicts Risk of Depression Onset in Alzheimer’s Disease
45. Faculty Opinions recommendation of Single-nucleus chromatin accessibility and transcriptomic characterization of Alzheimer's disease.
46. Chapter 4 - Lentiviral vectors as the delivery vehicles for transduction into iPSCs: shortcomings and benefits
47. Neurogenomics
48. Additional file 2 of Sex dependent glial-specific changes in the chromatin accessibility landscape in late-onset Alzheimer’s disease brains
49. Pleiotropy and allelic heterogeneity in the TOMM40-APOE genomic region related to clinical and metabolic features of hepatitis C infection
50. Cell-Type Specific Changes in DNA Methylation of SNCA Intron 1 in Synucleinopathy Brains
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