Search

Your search keyword '"Chikwe J"' showing total 396 results
Start Over Author "Chikwe J"
396 results on '"Chikwe J"'

4. Randomized Trial to Evaluate the Safety and Efficacy of the Sherpa Pak Device versus Cold Storage of Donor Hearts in Transplantation: A Pilot Study

Author

Esmailian, F., primary, Stotland, A., additional, Patel, J., additional, Emerson, D., additional, Mirocha, J., additional, Bowdish, M., additional, Catarino, P., additional, Megna, D., additional, Gunn, T., additional, Rafiei, M., additional, Babalola, O., additional, Daniels, A., additional, Kittleson, M., additional, Chang, D., additional, Kransdorf, E., additional, Nikolova, A., additional, Chikwe, J., additional, and Kobashigawa, J., additional

Published
2024
Full Text
View/download PDF

6. Robotic Lung Transplantation

Author

Thomas, J., primary, Emerson, D., additional, Chen, Q., additional, Malas, J., additional, Premananthan, S., additional, Krishnan, A., additional, Chikwe, J., additional, D'Atellis, N., additional, Rampolla, R., additional, Catarino, P., additional, and Megna, D., additional

Published
2023
Full Text
View/download PDF

8. Outcomes of Extremely Prolonged (> 50 Days) Venovenous Extracorporeal Membrane Oxygenation Support: A Single Center Experience

Author

Malas, J., primary, Chen, Q., additional, Premananthan, C., additional, Krishnan, A., additional, Shen, T., additional, Emerson, D., additional, Gunn, T., additional, Megna, D., additional, Catarino, P., additional, Nurok, M., additional, Bowdish, M., additional, Chikwe, J., additional, Cheng, S., additional, Ebinger, J., additional, and Kumaresan, A., additional

Published
2023
Full Text
View/download PDF

12. Expert systematic review on the choice of conduits for coronary artery bypass grafting: endorsed by the European Association for Cardio-Thoracic Surgery (EACTS) and The Society of Thoracic Surgeons (STS).

Author

Gaudino, M, Bakaeen, FG, Sandner, S, Aldea, GS, Arai, H, Chikwe, J, Firestone, S, Fremes, SE, Gomes, WJ, Bong-Kim, K, Kisson, K, Kurlansky, P, Lawton, J, Navia, D, Puskas, JD, Ruel, M, Sabik, JF, Schwann, TA, Taggart, DP, Tatoulis, J, Wyler von Ballmoos, M, Gaudino, M, Bakaeen, FG, Sandner, S, Aldea, GS, Arai, H, Chikwe, J, Firestone, S, Fremes, SE, Gomes, WJ, Bong-Kim, K, Kisson, K, Kurlansky, P, Lawton, J, Navia, D, Puskas, JD, Ruel, M, Sabik, JF, Schwann, TA, Taggart, DP, Tatoulis, J, and Wyler von Ballmoos, M

Published
2023

14. Should Age-Based Eligibility Thresholds Differ for Repeat Heart Transplantation? Analysis of the United Network of Organ Sharing Database

Author

Chen, Q., primary, Roach, A., additional, Chan, J., additional, Gill, G., additional, Rowe, G., additional, Alhossan, A., additional, Thomas, J., additional, Peiris, A., additional, Megna, D., additional, Esmailian, F., additional, Catarino, P., additional, Chikwe, J., additional, and Emerson, D., additional

Published
2022
Full Text
View/download PDF

15. Intra-Aortic Balloon Pump or Impella 5.0/5.5 as a Bridge to Heart Transplantation?

Author

Chen, Q., primary, Roach, A., additional, Chan, J., additional, Peiris, A., additional, Tremblay, L., additional, Thomas, J., additional, Alhossan, A., additional, Moriguchi, J.D., additional, Cole, R., additional, Kobashigawa, J., additional, Catarino, P., additional, Esmailian, F., additional, Emerson, D., additional, Chikwe, J., additional, and Megna, D., additional

Published
2022
Full Text
View/download PDF

21. Impact of Minimally Invasive Lung Transplantation on Early Outcomes and Analgesia Use: A Matched Cohort Study

Author

Thomas, J., primary, Barnes, D., additional, Chikwe, J., additional, Chen, Q., additional, Roach, A., additional, Peiris, A., additional, Rowe, G., additional, Gill, G., additional, Alhossan, A., additional, Berliner, H., additional, Emerson, D., additional, Catarino, P., additional, Rampolla, R., additional, and Megna, D., additional

Published
2022
Full Text
View/download PDF

30. Posterior left pericardiotomy for the prevention of atrial fibrillation after cardiac surgery: an adaptive, single-centre, single-blind, randomised, controlled trial

Author

Gaudino, Mario Fulvio Luigi, Sanna, Tommaso, Ballman, K. V., Robinson, N. B., Hameed, I., Audisio, K., Rahouma, M., Di Franco, A., Soletti, G. J., Lau, C., Rong, L. Q., Massetti, Massimo, Gillinov, M., Ad, N., Voisine, P., Dimaio, J. M., Chikwe, J., Fremes, S. E., Crea, Filippo, Puskas, J. D., Girardi, L., Gaudino M. (ORCID:0000-0001-7529-438X), Sanna T. (ORCID:0000-0002-5760-6885), Massetti M. (ORCID:0000-0002-7100-8478), Crea F. (ORCID:0000-0001-9404-8846), Gaudino, Mario Fulvio Luigi, Sanna, Tommaso, Ballman, K. V., Robinson, N. B., Hameed, I., Audisio, K., Rahouma, M., Di Franco, A., Soletti, G. J., Lau, C., Rong, L. Q., Massetti, Massimo, Gillinov, M., Ad, N., Voisine, P., Dimaio, J. M., Chikwe, J., Fremes, S. E., Crea, Filippo, Puskas, J. D., Girardi, L., Gaudino M. (ORCID:0000-0001-7529-438X), Sanna T. (ORCID:0000-0002-5760-6885), Massetti M. (ORCID:0000-0002-7100-8478), and Crea F. (ORCID:0000-0001-9404-8846)

Abstract

Background: Atrial fibrillation is the most common complication after cardiac surgery and is associated with extended in-hospital stay and increased adverse outcomes, including death and stroke. Pericardial effusion is common after cardiac surgery and can trigger atrial fibrillation. We tested the hypothesis that posterior left pericardiotomy, a surgical manoeuvre that drains the pericardial space into the left pleural cavity, might reduce the incidence of atrial fibrillation after cardiac surgery. Methods: In this adaptive, randomised, controlled trial, we recruited adult patients (aged ≥18 years) undergoing elective interventions on the coronary arteries, aortic valve, or ascending aorta, or a combination of these, performed by members of the Department of Cardiothoracic Surgery from Weill Cornell Medicine at the New York Presbyterian Hospital in New York, NY, USA. Patients were eligible if they had no history of atrial fibrillation or other arrhythmias or contraindications to the experimental intervention. Eligible patients were randomly assigned (1:1), stratified by CHA2DS2-VASc score and using a mixed-block randomisation approach (block sizes of 4, 6, and 8), to posterior left pericardiotomy or no intervention. Patients and assessors were blinded to treatment assignment. Patients were followed up until 30 days after hospital discharge. The primary outcome was the incidence of atrial fibrillation during postoperative in-hospital stay, which was assessed in the intention-to-treat (ITT) population. Safety was assessed in the as-treated population. This study is registered with ClinicalTrials.gov, NCT02875405, and is now complete. Findings: Between Sept 18, 2017, and Aug 2, 2021, 3601 patients were screened and 420 were included and randomly assigned to the posterior left pericardiotomy group (n=212) or the no intervention group (n=208; ITT population). The median age was 61·0 years (IQR 53·0–70·0), 102 (24%) patients were female, and 318 (76%) were male, with a me

Published
2021

33. Heart in the Box with Long Term Outcome Post-Heart Transplantation

Author

Salabat, R., primary, Emerson, D., additional, Megna, D., additional, Ramzy, D., additional, Kobashigawa, J.A., additional, Thottam, M., additional, Singer-Englar, T., additional, Patel, J., additional, Kittleson, M., additional, Czer, L., additional, Trento, A., additional, Chikwe, J., additional, and Esmailian, F., additional

Published
2021
Full Text
View/download PDF

34. Committee Recommendations for Resuming Cardiac Surgery Activity in the SARS-CoV-2 Era: Guidance From an International Cardiac Surgery Consortium

Author

Chikwe, J, Gaudino, M, Hameed, I, Robinson, NB, Bakaeen, FG, Menicanti, L, Doenst, T, Zheng, Z, Lemma, M, Falk, V, Tatoulis, J, Girardi, LN, Fremes, S, Ruel, M, Chikwe, J, Gaudino, M, Hameed, I, Robinson, NB, Bakaeen, FG, Menicanti, L, Doenst, T, Zheng, Z, Lemma, M, Falk, V, Tatoulis, J, Girardi, LN, Fremes, S, and Ruel, M

Abstract

Recommendations for the safe and optimized resumption of cardiac surgery care, research, and education during the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) era were developed by a cardiovascular research consortium, based in 19 countries and representing a wide spectrum of experience with COVID-19. This guidance document provides a framework for restarting cardiac surgery in the outpatient and inpatient settings, in accordance with the current understanding of SARS-CoV-2, the risks posed by interrupted cardiovascular care, and the available recommendations from major societies.

Published
2020

35. Characteristics of Contemporary Randomized Clinical Trials and Their Association with the Trial Funding Source in Invasive Cardiovascular Interventions

Author

Gaudino, Mario Fulvio Luigi, Hameed, I., Rahouma, M., Khan, F. M., Tam, D. Y., Biondi-Zoccai, G., Demetres, M., Charlson, M. E., Ruel, M., Crea, Filippo, Falk, V., Girardi, L. N., Fremes, S., Chikwe, J., Gaudino M. (ORCID:0000-0001-7529-438X), Crea F. (ORCID:0000-0001-9404-8846), Gaudino, Mario Fulvio Luigi, Hameed, I., Rahouma, M., Khan, F. M., Tam, D. Y., Biondi-Zoccai, G., Demetres, M., Charlson, M. E., Ruel, M., Crea, Filippo, Falk, V., Girardi, L. N., Fremes, S., Chikwe, J., Gaudino M. (ORCID:0000-0001-7529-438X), and Crea F. (ORCID:0000-0001-9404-8846)

Abstract

Importance: Changes in evidence-based practice and guideline recommendations depend on high-quality randomized clinical trials (RCTs). Commercial device and pharmaceutical manufacturers are frequently involved in the funding, design, conduct, and reporting of trials, the implications of which have not been recently analyzed. Objective: To evaluate the design, outcomes, and reporting of contemporary randomized clinical trials of invasive cardiovascular interventions and their association with the funding source. Design, Setting, and Participants: This cross-sectional study analyzed published RCTs between January 1, 2008, to May 31, 2019. The trials included those involving coronary, vascular and structural interventional cardiology, and vascular and cardiac surgical procedures. Main Outcomes and Measures: We assessed (1) trial characteristics, (2) finding of a statistically significant difference in the primary end point favoring the experimental intervention, (3) reporting of implied treatment advantage in trials without significant differences in primary end point, (4) existence of major discrepancies between registered and published primary outcomes, (5) number of patients whose outcomes would need to switch from a nonevent to an event to convert a significant difference in primary end point to nonsignificant, and (6) association with funding source. Results: Of the 216 RCTs analyzed, 115 (53.2%) reported having commercial sponsorship. Most trials had 80% power to detect an estimated treatment effect of 30%, and 128 trials (59.3%) used composite primary end points. The median (interquartile range [IQR]) sample size was 502 (204-1702) patients, and the median (IQR) follow-up duration was 12 (1.0-14.4) months. Overall, 123 trials (57.0%) reported a statistically significant difference in the primary outcome favoring the experimental intervention; reporting strategies that implied an advantage were identified in 55 (65.5%) of 84 trials that reported nonsignificant di

Published
2020

50. Does previous percutaneous coronary stenting compromise the long-term efficacy of subsequent coronary artery bypass surgery? A microsimulation study

Author

Rao, C., Stanbridge Rde, L., Chikwe, J., Pepper, J., Skapinakis, P., Aziz, O., Darzi, A., and Athanasiou, T.

Subjects
Reoperation, Models, Cardiovascular, Models, Statistical, Time Factors, Quality-Adjusted Life Years, Stents, Angioplasty, Balloon, Coronary/methods/mortality, Markov Chains, Risk Assessment, Survival Analysis, Coronary Artery Bypass/methods/*mortality, Myocardial Revascularization/*methods, Cause of Death, Coronary Stenosis/radiography/*therapy, Quality of Life, Humans, Follow-Up Studies
Abstract

BACKGROUND: This study aims to compare long-term survival and health-related quality of life in patients undergoing coronary artery bypass surgery with and without previous coronary stenting. METHODS: Markov microsimulation was used to model long-term survival and quality of life after surgical revascularization using data from referenced sources. Probabilistic sensitivity analysis was used to investigate the effect of uncertainty associated with the model parameters on the microsimulation results. RESULTS: Percutaneous coronary stenting was found to significantly decrease the effectiveness of coronary surgery. The model suggests that after a single stenting procedure ten-year survival was reduced by 3.3% (SD 0.7%), from 79.9% (SD 1.3%) to 76.6% (SD 1.4%). Similarly, after multiple stenting procedures ten-year survival was reduced by 3.5% (SD 0.7%) to 76.4% (SD 1.4%). Over a ten-year period a single stenting procedure reduced the quality adjusted life year (QALY) payoff by 0.25 QALY (SD 0.11 QALY) and multiple stenting procedures reduced the QALY payoff by 0.27 QALY (SD 0.08 QALY). CONCLUSIONS: This study suggests that patients who undergo surgical bypass after stenting have worse long-term outcomes than patients who undergo surgical revascularization without previous percutaneous intervention. The pathophysiological mechanisms for this are not fully understood and must be further investigated. The findings of this study suggest that the timing of surgical bypass in relation to percutaneous intervention is important. This may have significant implications for clinical practice, suggesting that greater emphasis should be placed on selecting the optimum initial revascularization strategy. Ann Thorac Surg

Published
2008

Catalog

Books, media, physical & digital resources
See catalog results