Search

Your search keyword '"Chino S"' showing total 153 results
Start Over Author "Chino S"
153 results on '"Chino S"'

9. Heart Failure Postdischarge Clinic: A Pharmacist-led Approach to Reduce Readmissions

Author

Chino S. Aneke, Angela Cheng-Lai, Lendita Prlesi, Rasha Al-Bawardy, Samvit Tandan, Kiana Chen, Ileana L. Piña, Manaf Assafin, S. Murthy, and Shuo Xu

Subjects
Male, medicine.medical_specialty, Cardiotonic Agents, Outpatient Clinics, Hospital, Medication Therapy Management, Pharmacist, MEDLINE, Kaplan-Meier Estimate, Pharmacists, Patient Readmission, Professional Role, Secondary Prevention, Medicine, Outpatient clinic, Humans, Aged, Heart Failure, business.industry, General Medicine, Continuity of Patient Care, Middle Aged, medicine.disease, Heart failure, Pharmaceutical Services, Emergency medicine, Female, New York City, Health Services Research, Cardiology and Cardiovascular Medicine, business
Published
2018

10. Insulinlike Growth Factor Binding Protein-1 and Ghrelin Predict Health Outcomes Among Older Adults: Cardiovascular Health Study Cohort

Author

Bruce M. Psaty, Clara Dominguez-Islas, Garrett Strizich, Anne B. Newman, Chino S. Aneke-Nash, Anne R. Cappola, Lewis H. Kuller, Robert C. Kaplan, Jorge R. Kizer, Michael Pollak, Petra Bùžková, Christopher I. Li, Howard D. Strickler, and Thomas E. Rohan

Subjects
Adult, Male, 0301 basic medicine, medicine.medical_specialty, Endocrinology, Diabetes and Metabolism, Clinical Biochemistry, 030209 endocrinology & metabolism, Context (language use), Biochemistry, Cohort Studies, 03 medical and health sciences, 0302 clinical medicine, Endocrinology, Internal medicine, Diabetes mellitus, medicine, Humans, Insulin, Longitudinal Studies, Prospective Studies, Insulin-Like Growth Factor I, Prospective cohort study, Clinical Research Articles, Aged, Glucose tolerance test, medicine.diagnostic_test, business.industry, Biochemistry (medical), Hazard ratio, Fasting, Glucose Tolerance Test, Middle Aged, Prognosis, medicine.disease, Ghrelin, Insulin-Like Growth Factor Binding Protein 1, Insulin-Like Growth Factor Binding Protein 3, 030104 developmental biology, Cardiovascular Diseases, Cohort, Female, business, hormones, hormone substitutes, and hormone antagonists, Biomarkers, Follow-Up Studies, Cohort study
Abstract

Context:Multiple diseases may explain the association of the growth hormone/insulinlike growth factor-I (GH/IGF-I) axis with longevity.Objective:To relate circulating GH/IGF-I system protein levels with major health eventsDesign and Setting:This is a cohort study set in 4 US communities.Participants:Adults (N = 2268) 65 years and older free of diabetes and cardiovascular diseaseMeasurements:We assessed insulinlike growth factor binding protein-1 (IGFBP-1) and ghrelin in fasting and 2-hour oral glucose tolerance test (OGTT) blood samples, as well as fasting IGF-I and IGFBP-3. Hazard ratios for mortality and a composite outcome for first incident myocardial infarction, stroke, heart failure, hip fracture, or death were adjusted for sociodemographic, behavioral, and physiological covariates.Results:During 13,930 person-years of follow-up, 48.1% of individuals sustained one or more components of the composite outcome and 31.8% died. Versus the lowest quartiles, the highest quartiles of fasting and 2-hour ghrelin were associated with 27% higher (95% confidence interval [CI]: 6%, 53%) and 39% higher (95% CI: 14%, 71%) risks of the composite outcome, respectively. The highest quartile of 2-hour IGFBP-1 was associated with 35% higher (95% CI: 1%, 52%) risk of the composite end point. Similarly, higher mortality was significantly associated with higher fasting and 2-hour ghrelin levels and with 2-hour IGFBP-1 level. When examined together, 2-hour post-OGTT levels of IGFBP-1 and ghrelin tended to predict outcomes better than fasting levels.Conclusions:Circulating IGFBP-1 and ghrelin measured during an OGTT predicted major health events and death in older adults, which may explain the influence of the GH/IGF-I axis on lifespan and health.

Published
2016

11. Agreement between circulating IGF-I, IGFBP-1 and IGFBP-3 levels measured by current assays versus unavailable assays previously used in epidemiological studies

Author

Chino S. Aneke-Nash, Qibin Qi, Robert C. Kaplan, Michael Pollak, Xiaonan Xue, Petra Bůžková, Clara Dominguez-Islas, and Howard D. Strickler

Subjects
Male, 0301 basic medicine, medicine.medical_specialty, Endocrinology, Diabetes and Metabolism, Cardiovascular health, medicine.medical_treatment, Concordance, Enzyme-Linked Immunosorbent Assay, Bioinformatics, Article, Cohort Studies, Andrology, 03 medical and health sciences, Insulin-like growth factor, 0302 clinical medicine, Endocrinology, Cohen's kappa, Linear regression, Epidemiology, medicine, Humans, Insulin-Like Growth Factor I, Aged, Aged, 80 and over, business.industry, Reproducibility of Results, Insulin-Like Growth Factor Binding Protein 1, Epidemiologic Studies, Insulin-Like Growth Factor Binding Protein 3, 030104 developmental biology, Quartile, 030220 oncology & carcinogenesis, Female, business, Kappa
Abstract

Objective Levels of insulin-like growth factor (IGF) proteins are associated with the risk of cancer and mortality. IGF assays produced by Diagnostic Systems Laboratories (DSL) were widely used in epidemiological studies, were not calibrated against recommended standards and are no longer commercially available. Design In a split sample study among 1471 adults participating in the Cardiovascular Health Study, we compared values obtained using DSL assays with alternative assays for serum IGF-I (Immunodiagnostic Systems, IDS), IGFBP-1 (American Laboratory Products Company, ALPCO) and IGFBP-3 (IDS). Results Results were compared using kernel density estimation plots, quartile analysis with weighted kappa statistics and linear regression models to assess the concordance of data from the different assays. Participants had a mean age of 77years. Results between alternative assays were strongly correlated (IGF-I, r =0.93 for DSL versus IDS; log-IGFBP-1, r =0.90 for DSL versus ALPCO; IGFBP-3, r =0.92 for DSL versus IDS). Cross tabulations showed that participants were usually in the same quartile categories regardless of the assay used (overall agreement, 74% for IGF-I, 64% for IGFBP-1, 71% for IGFBP-3). Weighted kappa also showed substantial agreement between assays (k w , 0.78 for IGF-I, 0.69 for IGFBP-1, 0.76 for IGFBP-3). Regressions of levels obtained with DSL assays (denoted X) to alternative assays were, IGF-I: 0.52X+15.2ng/ml, log-IGFBP-1: 1.01X−1.73ng/ml IGFBP-3: 0.87X+791.1ng/ml. Serum values of IGF-I, IGFBP-1 and IGFBP-3 measured using alternative assays are moderately correlated. Conclusions Care is needed in the interpretation of data sets involving IGF analytes if assay methodologies are not uniform.

Published
2016

13. The Association Between IGF-I and IGFBP-3 and Incident Diabetes in an Older Population of Men and Women in the Cardiovascular Health Study

Author

Kenneth J. Mukamal, Xiaonan Xue, Chino S. Aneke-Nash, Mary L. Biggs, Howard D. Strickler, David S. Siscovick, Robert C. Kaplan, Qibin Qi, Bruce M. Psaty, Lewis H. Kuller, Anne R. Cappola, and Michael Pollak

Subjects
0301 basic medicine, Blood Glucose, Male, Risk, medicine.medical_specialty, Diabetes risk, Endocrinology, Diabetes and Metabolism, Clinical Biochemistry, 030209 endocrinology & metabolism, Context (language use), Biochemistry, Cohort Studies, 03 medical and health sciences, 0302 clinical medicine, Endocrinology, New England, Diabetes mellitus, Internal medicine, medicine, Diabetes Mellitus, Glucose homeostasis, Humans, Longitudinal Studies, Prospective Studies, Insulin-Like Growth Factor I, Prospective cohort study, Clinical Research Articles, Aged, Aged, 80 and over, business.industry, Incidence, Biochemistry (medical), Hazard ratio, medicine.disease, 030104 developmental biology, Insulin-Like Growth Factor Binding Protein 3, Cardiovascular Diseases, Cohort, Female, business, hormones, hormone substitutes, and hormone antagonists, Biomarkers, Cohort study
Abstract

ContextInsulin-like growth factor-I (IGF-I) has structural and functional similarities to insulin and may play a role in glucose homeostasis, along with insulin-like growth factor binding protein-3 (IGFBP-3), which binds the majority of circulating IGF-I.ObjectiveTo assess whether IGF-I and IGFBP-3 are associated with a higher risk of incident diabetes in older adults.DesignParticipants in the Cardiovascular Health Study (n = 3133), a cohort of adults aged ≥65 years, were observed for 16 years (n = 3133) for the development of incident diabetes. Statistical models were fit separately for men and women because of interactions with sex (P interaction: IGF-I, 0.02; IGFBP-3, 0.009) and were adjusted for relevant covariates.SettingGeneral community.ParticipantsOlder adults who were nondiabetic at baseline and who did not develop diabetes within the first year of follow-up.InterventionsNot applicable.Main Outcome MeasureIncident diabetes as measured by fasting plasma glucose (FPG) ≥126 mg/dL, non-FPG ≥200 mg/dL, use of pharmacological treatment of diabetes, or existence of two or more inpatient or three or more outpatient or (at least one inpatient and at least one outpatient) Centers for Medicare & Medicaid Services claims with the diagnostic International Classification of Diseases, Ninth Revision, Clinical Modification code of 250.xx.ResultsIn women, higher IGFBP-3 (hazard ratio tertile 3 vs tertile 1 = 2.30; 95% confidence interval, 1.55 to 3.40; P trend < 0.0001) was significantly associated with incident diabetes. Total IGF-I was not significantly associated with incident diabetes. In men, neither IGF-I nor IGFBP-3 was significantly associated with incident diabetes.ConclusionsWe confirmed a previously reported association between circulating IGFBP-3 and diabetes risk in the older adult population, establishing that this association is present among women but could not be shown to be associated in men.

Published
2017

14. Changes in IGF-I and its Binding Proteins Are Associated with Diabetes in Older Adults

Author

Aneke, Chino S., Parrinello, Christina M., Rajpathak, Swapnil N., Rohan, Thomas E., Strotmeyer, Elsa S., Kritchevsky, Stephen B., Psaty, Bruce M., Bůžková, Petra, Kizer, Jorge R., Newman, Anne B., Strickler, Howard D., and Kaplan, Robert C.

Subjects
Blood Glucose, Cohort Studies, Insulin-Like Growth Factor Binding Protein 1, Male, Insulin-Like Growth Factor Binding Protein 3, Diabetes Mellitus, Type 2, Humans, Female, Insulin-Like Growth Factor I, Article, Aged, Retrospective Studies
Abstract

To determine whether changes in insulin-like growth factor (IGF) protein levels are greater in participants with type 2 diabetes mellitus or worsening glycemia than in normoglycemic individuals over a 9-year follow-up period.Retrospective analysis of a cohort study.Participants were recruited from North Carolina, California, Maryland, and Pennsylvania.Cardiovascular Health Study All Stars participants, a cohort study of community-dwelling adults aged 65 and older (N=897).Plasma IGF-I, IGF binding protein (IGFBP)-1, and IGFBP-3 levels were assessed and American Diabetes Association cut-points for impaired glucose tolerance (IGT), impaired fasting glucose (IFG), and diabetes mellitus were used to classify participants at baseline (1996-97) and follow-up (2005-06).At baseline, mean age was 76.3±3.6, and 18.5% had diabetes mellitus. Participants with IFG alone and IGT plus IFG had higher IGF-I levels and lower IGFBP-1 levels than those with normoglycemia or diabetes mellitus. The greatest percentage change in IGF levels occurred in those who had diabetes mellitus at baseline (9-year changes: -9.3% for IGF-I, 59.7% for IGFBP-1, -13.4% for IGFBP-3), the smallest in individuals who remained normoglycemic at follow-up (9-year changes: -3.7% for IGF-I, 25.6% for IGFBP-1, -6.4% for IGFBP-3), and intermediate in those who were normoglycemic but developed IFG at follow-up.Degrees of glycemic impairment are associated with varying degrees of change in IGF protein levels. The changes observed in the diabetes mellitus group have been previously shown to be associated with heart failure, cancer, and noncancer mortality.

Published
2015

15. INTRAVENOUS DILTIAZEM, AS COMPARED TO INTRAVENOUS METOPROLOL, FOR ATRIAL FIBRILLATION/FLUTTER IS ASSOCIATED WITH INCREASED ADMISSION FROM THE EMERGENCY DEPARTMENT

Author

Daniele Massera, Chino S. Aneke, Ileana L. Piña, and Ching Wei Chen

Subjects
medicine.medical_specialty, Atrial fibrillation flutter, business.industry, Atrial fibrillation, macromolecular substances, Emergency department, medicine.disease, Internal medicine, cardiovascular system, Cardiology, medicine, Flutter, cardiovascular diseases, Diltiazem, Cardiology and Cardiovascular Medicine, business, medicine.drug, Metoprolol
Abstract

Atrial fibrillation (AF) is the most common arrhythmia encountered in the emergency department (ED). Intravenous metoprolol (IV-M) and diltiazem (IV-D) have become the most commonly used agents in their respective class for the acute treatment of atrial fibrillation/flutter with a rapid ventricular

Published
2016

31. [Álbum de historia natural].

Author

Anónimo chino s. XVIII and Anónimo chino s. XVIII

Abstract

Álbum compuesto por 80 dibujos de artrópodos y otras especies, realizados en gouache. Cada dibujo está acompañado de una inscripción en caracteres chinos que identifica al animal o insecto representado. La forma de ejecutar los trazos de los caracteres varía de unos dibujos a otros, lo cual, unido a la presencia de algunos errores, sugiere la intervención de varias manos. La transcripción al alfabeto latino que figura junto a los caracteres chinos parece ser de origen cantonés, Título tomado de la ficha topográfica de la BNE: "Álbum de historia natural, dividido en seis volúmenes", Fecha basada en la similitud con los álbumes de dibujos pertenecientes a la colección de Jean Theodore Royer (entre 1760 y 1807), así como en el tipo de encuadernación y los sellos de la Biblioteca Nacional presentes en los dibujos, Los dibujos están realizados sobre un papel muy fino, pegado posteriormente sobre las hojas del álbum, Campen, Jan van. Collecting China : Jean Theodore Royer (1737-1807), collections and Chinese studies. 2021, Álbum compuesto por 80 dibujos de artrópodos y otras especies, realizados en gouache. Cada dibujo está acompañado de una inscripción en caracteres chinos que identifica al animal o insecto representado. La forma de ejecutar los trazos de los caracteres varía de unos dibujos a otros, lo cual, unido a la presencia de algunos errores, sugiere la intervención de varias manos. La transcripción al alfabeto latino que figura junto a los caracteres chinos parece ser de origen cantonés

32. [Álbum de historia natural].

Author

Anónimo chino s. XVIII and Anónimo chino s. XVIII

Abstract

Álbum compuesto por 84 dibujos de artrópodos, reptiles, anfibios y otras especies, realizados en gouache. Cada dibujo está acompañado de una inscripción en caracteres chinos que identifica al animal o insecto representado. La forma de ejecutar los trazos de los caracteres varía de unos dibujos a otros, lo cual, unido a la presencia de algunos errores, sugiere la intervención de varias manos. La transcripción al alfabeto latino que figura junto a los caracteres chinos parece ser de origen cantonés, Título tomado de la ficha topográfica de la BNE: "Álbum de historia natural, dividido en seis volúmenes", Fecha basada en la similitud con los álbumes de dibujos pertenecientes a la colección de Jean Theodore Royer (entre 1760 y 1807), así como en el tipo de encuadernación y los sellos de la Biblioteca Nacional presentes en los dibujos, Los dibujos están realizados sobre un papel muy fino, pegado posteriormente sobre las hojas del álbum, Campen, Jan van. Collecting China : Jean Theodore Royer (1737-1807), collections and Chinese studies. 2021, Álbum compuesto por 84 dibujos de artrópodos, reptiles, anfibios y otras especies, realizados en gouache. Cada dibujo está acompañado de una inscripción en caracteres chinos que identifica al animal o insecto representado. La forma de ejecutar los trazos de los caracteres varía de unos dibujos a otros, lo cual, unido a la presencia de algunos errores, sugiere la intervención de varias manos. La transcripción al alfabeto latino que figura junto a los caracteres chinos parece ser de origen cantonés

33. [Álbum de historia natural].

Author

Anónimo chino s. XVIII and Anónimo chino s. XVIII

Abstract

Álbum compuesto por 84 dibujos de artrópodos, moluscos, anfibios y otras especies, realizados en gouache. Cada dibujo está acompañado de una inscripción en caracteres chinos que identifica al animal o insecto representado. La forma de ejecutar los trazos de los caracteres varía de unos dibujos a otros, lo cual, unido a la presencia de algunos errores, sugiere la intervención de varias manos. La transcripción al alfabeto latino que figura junto a los caracteres chinos parece ser de origen cantonés, Título tomado de la ficha topográfica de la BNE: "Álbum de historia natural, dividido en seis volúmenes", Fecha basada en la similitud con los álbumes de dibujos pertenecientes a la colección de Jean Theodore Royer (entre 1760 y 1807), así como en el tipo de encuadernación y los sellos de la Biblioteca Nacional presentes en los dibujos, Los dibujos están realizados sobre un papel muy fino, pegado posteriormente sobre las hojas del álbum, Campen, Jan van. Collecting China : Jean Theodore Royer (1737-1807), collections and Chinese studies. 2021, Álbum compuesto por 84 dibujos de artrópodos, moluscos, anfibios y otras especies, realizados en gouache. Cada dibujo está acompañado de una inscripción en caracteres chinos que identifica al animal o insecto representado. La forma de ejecutar los trazos de los caracteres varía de unos dibujos a otros, lo cual, unido a la presencia de algunos errores, sugiere la intervención de varias manos. La transcripción al alfabeto latino que figura junto a los caracteres chinos parece ser de origen cantonés

34. [Álbum de historia natural].

Author

Anónimo chino s. XVIII and Anónimo chino s. XVIII

Abstract

Álbum compuesto por 80 dibujos de artrópodos y otras especies, y sus nidos, realizados en gouache. Cada dibujo está acompañado de una inscripción en caracteres chinos que identifica al animal o insecto representado. La forma de ejecutar los trazos de los caracteres varía de unos dibujos a otros, lo cual, unido a la presencia de algunos errores, sugiere la intervención de varias manos. La transcripción al alfabeto latino que figura junto a los caracteres chinos parece ser de origen cantonés, Título tomado de la ficha topográfica de la BNE: "Álbum de historia natural, dividido en seis volúmenes", Fecha basada en la similitud con los álbumes de dibujos pertenecientes a la colección de Jean Theodore Royer (entre 1760 y 1807), así como en el tipo de encuadernación y los sellos de la Biblioteca Nacional presentes en los dibujos, Los dibujos están realizados sobre un papel muy fino, pegado posteriormente sobre las hojas del álbum, Campen, Jan van. Collecting China : Jean Theodore Royer (1737-1807), collections and Chinese studies. 2021, Álbum compuesto por 80 dibujos de artrópodos y otras especies, y sus nidos, realizados en gouache. Cada dibujo está acompañado de una inscripción en caracteres chinos que identifica al animal o insecto representado. La forma de ejecutar los trazos de los caracteres varía de unos dibujos a otros, lo cual, unido a la presencia de algunos errores, sugiere la intervención de varias manos. La transcripción al alfabeto latino que figura junto a los caracteres chinos parece ser de origen cantonés

35. [Álbum de historia natural].

Author

Anónimo chino s. XVIII and Anónimo chino s. XVIII

Abstract

Álbum compuesto por 72 dibujos de peces y otras especies marinas realizados en acuarelas, con detalles en gouache y realzados con pigmentos plateados. Cada dibujo está acompañado de una inscripción en caracteres chinos que identifica al pez representado. La forma de ejecutar los trazos de los caracteres varía de unos dibujos a otros, lo cual, unido a la presencia de algunos errores, sugiere la intervención de varias manos. La transcripción al alfabeto latino que figura junto a los caracteres chinos parece ser de origen cantonés, Título tomado de la ficha topográfica de la BNE: "Álbum de historia natural, dividido en seis volúmenes", Fecha basada en la similitud con los álbumes de dibujos pertenecientes a la colección de Jean Theodore Royer (entre 1760 y 1807), así como en el tipo de encuadernación y los sellos de la Biblioteca Nacional presentes en los dibujos, Los dibujos están realizados sobre un papel muy fino, pegado posteriormente sobre las hojas del álbum, Campen, Jan van. Collecting China : Jean Theodore Royer (1737-1807), collections and Chinese studies. 2021, Álbum compuesto por 72 dibujos de peces y otras especies marinas realizados en acuarelas, con detalles en gouache y realzados con pigmentos plateados. Cada dibujo está acompañado de una inscripción en caracteres chinos que identifica al pez representado. La forma de ejecutar los trazos de los caracteres varía de unos dibujos a otros, lo cual, unido a la presencia de algunos errores, sugiere la intervención de varias manos. La transcripción al alfabeto latino que figura junto a los caracteres chinos parece ser de origen cantonés

36. [Álbum de historia natural].

Author

Anónimo chino s. XVIII and Anónimo chino s. XVIII

Abstract

Álbum compuesto por 72 dibujos de peces y otras especies marinas realizados en acuarelas, con detalles en gouache y realzados con pigmentos plateados. Cada dibujo está acompañado de una inscripción en caracteres chinos que identifica al pez representado. La forma de ejecutar los trazos de los caracteres varía de unos dibujos a otros, lo cual, unido a la presencia de algunos errores, sugiere la intervención de varias manos. La transcripción al alfabeto latino que figura junto a los caracteres chinos parece ser de origen cantonés, Título tomado de la ficha topográfica de la BNE: "Álbum de historia natural, dividido en seis volúmenes", Fecha basada en la similitud con los álbumes de dibujos pertenecientes a la colección de Jean Theodore Royer (entre 1760 y 1807), así como en el tipo de encuadernación y los sellos de la Biblioteca Nacional presentes en los dibujos, Los dibujos están realizados sobre un papel muy fino, pegado posteriormente sobre las hojas del álbum, Campen, Jan van. Collecting China : Jean Theodore Royer (1737-1807), collections and Chinese studies. 2021, Álbum compuesto por 72 dibujos de peces y otras especies marinas realizados en acuarelas, con detalles en gouache y realzados con pigmentos plateados. Cada dibujo está acompañado de una inscripción en caracteres chinos que identifica al pez representado. La forma de ejecutar los trazos de los caracteres varía de unos dibujos a otros, lo cual, unido a la presencia de algunos errores, sugiere la intervención de varias manos. La transcripción al alfabeto latino que figura junto a los caracteres chinos parece ser de origen cantonés

45. De la gestión de riesgo de desastres a la gestión para el desarrollo sostenible: enfoques conceptuales.

Author

Javier-Silva, L. A., Portuguez-Maurtua, M., Chávez-Juanito, Yuli A., and Condori-Chino, S. F.

Subjects
*EMERGENCY management, *PSYCHOLOGICAL vulnerability, *CONSTRUCTION management, *SUSTAINABLE development, *DISASTER relief, *SOCIAL skills, *SOCIAL structure, *ENVIRONMENTAL education
Abstract

Disasters are unpredictable events that worsen adequate social functioning. According to the perspective that is assumed, these can be of natural origin, anthropic or a formation of forces between both elements, being a process of breakdown, where material and immaterial losses are produced, leading to a generalized crisis that affects social structures. from its foundations and, on many occasions, is lasting over time. By virtue of the foregoing, the article analyzes the theoretical-conceptual guidelines of disasters, in interaction with the postulates of disaster risk management, understood as a series of strategies that allow facing vulnerabilities in the face of natural phenomena. It implies international attention, support for the community, as well as moving towards the construction of a management model designed for sustainability. Managing for sustainable development means dealing with environmental and human problems, proposing equity and social justice, consistent ideas, an inclusive and interdisciplinary model, with future prospects. [ABSTRACT FROM AUTHOR]

Published
2022
Full Text
View/download PDF

47. Evaluation of Effectiveness of Thoracic Endovascular Treatment for Infectious Aortic Diseases.

Author

Kato H, Kato N, Ouchi T, Higashigawa T, Nakajima K, Chino S, Ito H, Tokui T, Mizumoto T, Oue K, Ichikawa Y, and Sakuma H

Abstract

Purpose: The aim of study is to investigate the efficacy of thoracic endovascular aortic repair for infectious aortic diseases., Materials and Methods: Patients who underwent thoracic endovascular repair for infectious aortic diseases including mycotic thoracic aortic aneurysm, aorto-bronchial fistula and aorto-enteric fistula from December 2011 to October 2022 at four institutions were retrospectively studied. The primary outcome of the study was overall survival, whereas the secondary outcome was comprehensive adverse event. Comprehensive adverse events were defined as a combination of deaths, aortic events, and infectious adverse events., Results: A total of 28 patients were included in the analysis, with 13 patients having mycotic thoracic aortic aneurysms, 12 having aorto-bronchial fistulas, and 3 having aorto-enteric fistulas. Seven patients (25%) underwent additional procedures (abscess drainage, 6 cases; total esophagectomy, 1 case). The mean follow-up period was 30.0 ± 33.9 months. The 1-year and 5-year survival rates were 85.7% and 67.9%, respectively. The 1-year and 5-year aorta-related complication-free survival rates were 64.3% and 42.9%, respectively. On univariate analysis, the presence of an aorto-bronchial fistula was associated with a higher risk of comprehensive adverse events (odds ratio [OR] = 11, P = 0.04)., Conclusion: TEVAR might be a promising treatment for infectious thoracic aortic diseases. Among the infectious pathologies, ABF was considered ominous in terms of late outcomes., (Copyright © 2024. Published by Elsevier Inc.)

Published
2024
Full Text
View/download PDF

49. Evaluation of Thoracic Endovascular Repair for the Treatment of Type B Aortic Dissection Complicated by Malperfusion.

Author

Kato H, Kato N, Ouchi T, Higashigawa T, Ito H, Nakajima K, Chino S, Tokui T, Mizumoto T, Oue K, Ichikawa Y, and Sakuma H

Abstract

Objectives: This study aims to investigate the efficacy of thoracic endovascular aortic repair (TEVAR) for type B aortic dissection (TBAD) complicated by malperfusion. Methods: This retrospective study included patients who underwent TEVAR for the treatment of TBAD complicated by malperfusion from June 1998 to June 2022 in four institutions. In addition to the common outcomes, including short- and medium-term mortality and morbidity, the preservation of each organ was investigated. Results: A total of 23 patients were included in this analysis. The 30-day mortality was 4% (1/23) of the patients. The overall survival rate was 87% at 1 year. The preservation rate of each organ was 33% (4/12) for the visceral organs, 85% (17/20) for the kidneys, and 100% (18/18) for the legs. Fisher's exact test showed a significant difference in the preservation rate between the viscera and the other organs ( P = 0.018 vs. kidneys, P = 0.0025 vs. legs). It was shown that the survival rate of patients with visceral malperfusion was significantly lower than that of patients with non-visceral malperfusion ( P = 0.006). Conclusion: In terms of mortality, TEVAR showed satisfactory results. The preservation of visceral organs was still challenging even with TEVAR and adjunctive measures., (@ 2024 The Editorial Committee of Annals of Vascular Diseases.)

Published
2024
Full Text
View/download PDF

50. The outcomes and cost analysis of open repair and endovascular aneurysm repair for abdominal aortic aneurysms: a single-center experience in Japan.

Author

Maze Y, Tokui T, Inoue R, Sekoguchi T, Narukawa T, Murakami M, Inoue R, Hirano K, Chino S, Nakajima K, Kato N, and Ito H

Abstract

Purpose: Japan has adopted its own reimbursement system, which differs from other countries in terms of its diagnostic procedure combination (DPC) methods. However, there are few reports on the cost analysis of open repair and endovascular aneurysm repair (EVAR) for abdominal aortic aneurysms in Japan. We aimed to evaluate the long-term outcomes and cost-effectiveness of these two procedures., Methods: This study included patients who underwent open repair (n = 224) and EVAR (n = 87) between January 2012 and December 2022. After propensity score matching, we compared the two groups., Results: The drug and blood products, procedures, and DPC costs were significantly higher in the open repair group (p < 0.001) than in the EVAR group. The surgical equipment and total costs were significantly higher in the EVAR group than in the open repair group (p < 0.001). There was no significant difference in the 5-year survival rate (88.5% in the open repair group vs. 72.0% in the EVAR group; p = 0.33) and freedom from re-intervention rate at 5 years (93.1% in the open repair group vs. 89.9% in the EVAR group; p = 0.15) between the two groups., Conclusions: Open repair is more cost-effective than EVAR. The cost-effectiveness of EVAR may therefore depend on the cost of the endograft., (© 2024. The Author(s) under exclusive licence to Springer Nature Singapore Pte Ltd.)

Published
2024
Full Text
View/download PDF

Catalog

Books, media, physical & digital resources
See catalog results