206 results on '"Cho, Heeyeong"'
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2. A novel IRAK4/PIM1 inhibitor ameliorates rheumatoid arthritis and lymphoid malignancy by blocking the TLR/MYD88-mediated NF-κB pathway
3. N-(2,7-dimethyl-2-alkyl-2H-chromen-6-yl)sulfonamide derivatives as selective serotonin 5-HT6 receptor antagonists: Design, synthesis, and biological evaluation
4. Azathioprine antagonizes aberrantly elevated lipid metabolism and induces apoptosis in glioblastoma
5. Real-Time Monitoring of Molecules in Aqueous Solution via a Surface-Functionalized Ag-Anodic Aluminum Oxide Surface-Enhanced Raman Scattering Platform.
6. Guidelines for Manufacturing and Application of Organoids: Brain
7. Small Molecule Destabilizer of β-Catenin and Ras Proteins Antagonizes Growth of K-Ras Mutation-Driven Colorectal Cancers Resistant to EGFR Inhibitors
8. Rational design of novel diaryl ether-linked benzimidazole derivatives as potent and selective BACE1 inhibitors
9. Manufacturing Uniform Cerebral Organoids for Neurological Disease Modeling and Drug Evaluation
10. Design, synthesis, biological evaluation and molecular modelling of 2-(2-aryloxyphenyl)-1,4-dihydroisoquinolin-3(2H)-ones: A novel class of TSPO ligands modulating amyloid-β-induced mPTP opening
11. A novel sphingosylphosphorylcholine and sphingosine-1-phosphate receptor 1 antagonist, KRO-105714, for alleviating atopic dermatitis
12. MeCP2 dysfunction prevents proper BMP signaling and neural progenitor expansion in brain organoid
13. Discovery of potent and selective cytotoxic activity of new quinazoline-ureas against TMZ-resistant glioblastoma multiforme (GBM)
14. Novel N-biphenyl-2-ylmethyl 2-methoxyphenylpiperazinylalkanamides as 5-HT7R antagonists for the treatment of depression
15. Effect of bexarotene on differentiation of glioblastoma multiforme compared with ATRA
16. Colon-Targeted Trans-Cinnamic Acid Ameliorates Rat Colitis by Activating GPR109A
17. Novel pyrimidoazepine analogs as serotonin 5-HT2A and 5-HT2C receptor ligands for the treatment of obesity
18. Discovery of 4-(phenyl)thio-1H-pyrazole derivatives as agonists of GPR109A, a high affinity niacin receptor
19. Uncompetitive Inhibitors of Alcohol Dehydrogenases
20. Discovery of GSK3β Inhibitors through In Silico Prediction-and-Experiment Cycling Strategy, and Biological Evaluation
21. A Small Molecule Promoting Neural Differentiation Suppresses Cancer Stem Cells in Colorectal Cancer
22. A Destabilizer of Both Wnt/β-Catenin and Ras/ERK Pathways Suppresses Cancer Stem Cell Activation in Colorectal Cancer
23. High performance inkjet printed embedded electrochemical sensors for monitoring hypoxia in a gut bilayer microfluidic chip
24. Inhibition of c-Kit signaling by diosmetin isolated from Chrysanthemum morifolium
25. Colon-Targeted Trans-Cinnamic Acid Ameliorates Rat Colitis by Activating GPR109A.
26. Glioblastoma patient-derived cell-based phenotypic drug screening and identification of possible action mechanisms through proteomic analysis
27. Sphingosylphosphorylcholine Attenuated β–Amyloid Production by Reducing BACE1 Expression and Catalysis in PC12 Cells
28. Synthesis and antibacterial evaluation of 1β-methyl-2-[5-(1-methoxyimino-2-substituted sulfonamide ethyl)pyrrolidin-3-ylthio]carbapenems and their related compounds
29. Development of a time-resolved fluorometric assay for the high throughput screening of melanin concentrating hormone receptor antagonists
30. Fucoidan from Undaria pinnatifida Induces Apoptosis in A549 Human Lung Carcinoma Cells
31. Screening of Kit Inhibitors: Suppression of Kit Signaling and Melanogenesis by Emodin
32. A Furanquinone from Paulownia tomentosa Stem for a New Cathepsin K Inhibitor
33. KKHA-761, a potent D 3 receptor antagonist with high 5-HT 1A receptor affinity, exhibits antipsychotic properties in animal models of schizophrenia
34. Specificity of alcohol dehydrogenases for sulfoxides
35. Flexibility of liver alcohol dehydrogenase in stereoselective binding of 3-butylthiolane 1-oxides
36. KKHA-761, a potent D3 receptor antagonist with high 5-HT1A receptor affinity, exhibits antipsychotic properties in animal models of schizophrenia
37. Modulation of the activity of pro-inflammatory enzymes, COX-2 and iNOS, by chrysin derivatives
38. Pharmacological actions of a novel and selective dopamine D3 receptor antagonist, KCH-1110
39. Pharmacological actions of a novel and selective dopamine D 3 receptor antagonist, KCH-1110
40. Properties of differentiated SH-SY5Y grown on carbon-based materials
41. 5-Aminosalicylic Acid Azo-Coupled with a GPR109A Agonist Is a Colon-Targeted Anticolitic Codrug with a Reduced Risk of Skin Toxicity
42. Synthesis of (3S,4S)-4-aminopyrrolidine-3-ol derivatives and biological evaluation for their BACE1 inhibitory activities
43. Design, synthesis, biological evaluation and molecular modelling of 2-(2-aryloxyphenyl)-1,4-dihydroisoquinolin-3(2 H )-ones: A novel class of TSPO ligands modulating amyloid-β-induced mPTP opening
44. Suppression of NFAT5-mediated Inflammation and Chronic Arthritis by Novel κB-binding Inhibitors
45. Biological evaluation of tanshindiols as EZH2 histone methyltransferase inhibitors
46. Indatraline inhibits Rho- and calcium-mediated glioblastoma cell motility and angiogenesis
47. 5-Aminosalicylic Acid Azo-Coupled with a GPR109A Agonist Is a Colon-Targeted Anticolitic Codrug with a Reduced Risk of Skin Toxicity
48. ChemInform Abstract: A New Amaryllidaceae Alkaloid from the Bulbs of Lycoris radiata.
49. Synthesis and biological evaluation of 3-aminopyrrolidine derivatives as CC chemokine receptor 2 antagonists
50. Inhibition of IKK-β: A new development in the mechanism of the anti-obesity effects of PTP1B inhibitors SA18 and SA32
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