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25 results on '"Choi, Hwan-Won"'

8. Molecular characteristics and pathogenic assessment of porcine epidemic diarrhoea virus isolates from the 2018 endemic outbreaks on Jeju Island, South Korea

Author

Lee, Sunhee, primary, Lee, Dong‐Uk, additional, Noh, Yun‐Hee, additional, Lee, Seung‐Chul, additional, Choi, Hwan‐Won, additional, Yang, Hyoung‐Seok, additional, Seol, Jun‐Ho, additional, Mun, Seong Hwan, additional, Kang, Won‐Myoung, additional, Yoo, Hyekyung, additional, and Lee, Changhee, additional

Published
2019
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11. Immunogenicity and safety of virus-like particle of the porcine encephalomyocarditis virus in pig

Author

Shin Bo-Hye, Choi Hwan-Won, Jeong WooSeog, Lee Won-Ha, Jeoung Hye-Young, Lee Hee, and An Dong-Jun

Subjects
EMCV, virus-like particles, vaccine candidate, Infectious and parasitic diseases, RC109-216
Abstract

Abstract Background In this study, porcine encephalomyocarditis virus (EMCV) virus-like particles (VLPs) were generated using a baculovirus expression system and were tested for immunogenicity and protective efficacy in vivo. Results VLPs were successfully generated from Sf9 cells infected with recombinant baculovirus and were confirmed to be approximately 30-40 nm by transmission electron microscopy (TEM). Immunization of mice with 0.5 μg crude protein containing the VLPs resulted in significant protection from EMCV infection (90%). In swine, increased neutralizing antibody titers were observed following twice immunization with 2.0 μg crude protein containing VLPs. In addition, high levels of neutralizing antibodies (from 64 to 512 fold) were maintained during a test period following the second immunization. No severe injection site reactions were observed after immunization and all swine were healthy during the immunization period Conclusion Recombinant EMCV VLPs could represent a new vaccine candidate to protect against EMCV infection in pig farms.

Published
2011
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13. Characterization of Salmonella enterica serovar Typhimurium and Salmonella enterica serovar 4,[5],12:i:- isolates from pigs presenting with diarrhea in Korea

Author

LEE, Ki-Eun, LEE, Deog-Yong, CHOI, Hwan-Won, CHAE, Su-Jin, YUN, Young-Sun, LEE, Ki-Chan, CHO, Yun-Sang, and YANG, Dong-Kun

Subjects
Diarrhea, Salmonella typhimurium, Swine Diseases, Salmonella Infections, Animal, Korea, Salmonella 4,[5],12:i, Swine, Salmonella enterica, Bacteriology, Note, Serogroup, Feces, Republic of Korea, Animals, S. Typhimurium
Abstract

Between 2011 and 2012, a total of 896 pig fecal samples were collected from nine provinces in Korea, and 50 salmonella enterica susp. enterica serovar Typhimurium (S. Typhimurium) was isolated. The characteristics of the 50 strains were analyzed, and 4 strains were identified as Salmonella enterica subsp. enterica serovar 4,[5],12:i:-. Salmonella 4,[5],12:i:- could not be distinguished from S. Typhimurium through phage typing, antimicrobial resistance testing or multiple-locus variable-number tandem repeat analysis (MLVA). However, among the four Salmonella 4,[5],12:i:- strains, one (KVCC-BA1400078) was identified as a Salmonella 4,[5],12:i:- clone isolated from humans in the United States, and another (KVCC-BA1400080) was identified as DT193, which has been primarily isolated from humans and animals in European countries. The presence of Salmonella 4,[5],12:i:- in Korea poses a significant threat of horizontal transfer between pigs and humans.

Published
2015

14. Phenotypic and genotypic analyses of an attenuated porcine reproductive and respiratory syndrome virus strain after serial passages in cultured porcine alveolar macrophages

Author

Lee, Seung-Chul, primary, Lee, Sunhee, additional, Yoo, Gun-Woo, additional, Choi, Hwan-Won, additional, Noh, Yun-Hee, additional, Park, Chang Eon, additional, Shin, Jae-Ho, additional, Yoon, In-Joong, additional, Kang, Shien-Young, additional, and Lee, Changhee, additional

Published
2018
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17. Association of the Serum Levels of Hepatocyte Growth Factor with Microvascular Complications in Type 2 Diabetes

Author

PARK, IE BYUNG, CHUNG, EUN A., CHOI, HWAN WON, CHA, DONG YOUB, SONG, IN KWAN, and CHOI, JONG SEONG

Subjects
Endothelial growth factors -- Measurement, Type 2 diabetes -- Research, Diabetic retinopathy -- Physiological aspects, Hypertension -- Physiological aspects, Health
Abstract

HGF(hepatocyte growth factor) is an endothelial growth factor and can stimulate endothelial cell motility, growth and neovascularization. Recently, several studies have been reported that the serum HGF levels were elevated [...]

Published
2000

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