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Your search keyword '"Chong, Crystal Chun Yuen"' showing total 11 results
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11 results on '"Chong, Crystal Chun Yuen"'

2. Deep-learning-based cardiovascular risk stratification using coronary artery calcium scores predicted from retinal photographs

Author

Rim, Tyler Hyungtaek, Lee, Chan Joo, Tham, Yih-Chung, Cheung, Ning, Yu, Marco, Lee, Geunyoung, Kim, Youngnam, Ting, Daniel S W, Chong, Crystal Chun Yuen, Choi, Yoon Seong, Yoo, Tae Keun, Ryu, Ik Hee, Baik, Su Jung, Kim, Young Ah, Kim, Sung Kyu, Lee, Sang-Hak, Lee, Byoung Kwon, Kang, Seok-Min, Wong, Edmund Yick Mun, Kim, Hyeon Chang, Kim, Sung Soo, Park, Sungha, Cheng, Ching-Yu, and Wong, Tien Yin

Published
2021
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5. Normative Data and Associations of OCT Angiography Measurements of the Macula

Author

Teo, Zhen Ling, primary, Sun, Christopher Ziyu, additional, Chong, Crystal Chun Yuen, additional, Tham, Yih-Chung, additional, Takahashi, Kengo, additional, Majithia, Shivani, additional, Teo, Cong Ling, additional, Rim, Tyler Hyungtaek, additional, Chua, Jacqueline, additional, Schmetterer, Leopold, additional, Cheung, Chui Ming Gemmy, additional, Wong, Tien Yin, additional, Cheng, Ching-Yu, additional, and Tan, Anna Cheng Sim, additional

Published
2022
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7. Retinal Nerve Fiber Layer Thickness and Rim Area Profiles in Asians

Author

Majithia, Shivani, primary, Tham, Yih-Chung, additional, Chong, Crystal Chun Yuen, additional, Yu, Marco, additional, Cheung, Carol Y., additional, Bikbov, Mukharram M., additional, Kazakbaeva, Gyulli M., additional, Wang, Ningli, additional, Hao, Jie, additional, Cao, Kai, additional, Wang, Ya Xing, additional, Sasaki, Mariko, additional, Ito, Yoshikazu, additional, Wong, Ian Y., additional, Cheuk-Hung Chan, Jonathan, additional, Khanna, Rohit C., additional, Marmamula, Srinivas, additional, Nakano, Eri, additional, Mori, Yuki, additional, Aung, Tin, additional, Wong, Tien Yin, additional, Jonas, Jost B., additional, Miyake, Masahiro, additional, Cheng, Ching-Yu, additional, Banerjee, Seema, additional, Chee, Miao Li, additional, Gilmanshin, Timur R., additional, Iakupova, Ellina M., additional, Matsuda, Fumihiko, additional, Mettla, Asha Latha, additional, Pang, Chi Pui, additional, Rim, Tyler, additional, Soh, Zhi-Da, additional, Tham, Clement C., additional, Tsubota, Kazuo, additional, Tsujikawa, Akitaka, additional, Bin Wei, Wen, additional, Wu, Jian, additional, Xu, Jie, additional, and Yuki, Kenya, additional

Published
2022
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8. Retinal photograph-based deep learning predicts biological age, and stratifies morbidity and mortality risk

Author

Nusinovici, Simon, primary, Rim, Tyler Hyungtaek, additional, Yu, Marco, additional, Lee, Geunyoung, additional, Tham, Yih-Chung, additional, Cheung, Ning, additional, Chong, Crystal Chun Yuen, additional, Da Soh, Zhi, additional, Thakur, Sahil, additional, Lee, Chan Joo, additional, Sabanayagam, Charumathi, additional, Lee, Byoung Kwon, additional, Park, Sungha, additional, Kim, Sung Soo, additional, Kim, Hyeon Chang, additional, Wong, Tien-Yin, additional, and Cheng, Ching-Yu, additional

Published
2022
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9. Relationship between dry eye symptoms and quality of life: associations and mediation analysis

Author

Lim, Elizabeth Wen Ling, Chong, Crystal Chun Yuen, Nusinovici, Simon, Fenwick, Eva, Lamoureux, Ecosse Luc, Sabanayagam, Charumathi, Cheng, Ching-Yu, and Tong, Louis

Abstract

Purpose(1) To determine the independent association of dry eye symptoms with health-related quality of life (HRQoL) in the Singapore population and (2) to further investigate which factors mediate this association.MethodsIn this cross-sectional study, 7707 participants were included. The presence of dry eye symptoms was defined as experiencing at least one out of the six symptoms either ‘often’ or ‘all the time’. The EuroQoL-5 dimensions (EQ-5D) utility instrument (raw scores converted to UK time trade-off (TTO) values) was used to assess generic HRQoL and the overall score from the Visual Functioning Questionnaire for visual functioning. The association between dry eye symptoms and EQ-5D was investigated using multivariable linear regression, adjusting for demographic and socioeconomic information, comorbidities, systemic and ocular examinations results. Mediation analysis was used to determine whether certain factors mediated this association.ResultsAfter adjusting for relevant factors, those with dry eye symptoms had significantly lower HRQoL (difference in EQ-5D TTO: −0.062 (95% CI −0.073 to –0.050)), with the inability to open eyes affected the most (−0.101 (95% CI −0.161 to –0.042)), followed by a sandy sensation (−0.089 (95% CI −0.121 to –0.058)), a burning sensation (−0.070 (95% CI −0.105 to –0.036)), red eyes (−0.059 (95% CI −0.082 to –0.036)), a dry sensation (−0.058 (95% CI −0.072 to –0.044)) and crusting of eyelids (−0.040 (95% CI −0.071 to –0.008)). Visual functioning and the presence of recent falls accounted for 8.63% (4.98%–14.5%) and 2.93% (0.04%–5.68%) of the indirect relationship between dry eye and HRQoL, respectively.ConclusionDry eye symptoms were independently associated with poor HRQoL. Moreover, this was partly mediated by reduced visual functioning and experiencing recent falls. Our results suggest that efforts to reduce severity of dry eye symptoms are essential to optimise patients’ overall functioning and well-being.

Published
2023
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11. Associations between Chronic Kidney Disease and Thinning of Neuroretinal Layers in Multiethnic Asian and White Populations.

Author

Majithia S, Chong CCY, Chee ML, Yu M, Soh ZD, Thakur S, Lavanya R, Rim TH, Nusinovici S, Koh V, Sabanayagam C, Cheng CY, and Tham YC

Abstract

Purpose: To evaluate the relationships between chronic kidney disease (CKD) with retinal nerve fiber layer (RNFL) and ganglion cell-inner plexiform layer (GCIPL) thickness profiles of eyes in Asian and White populations., Design: Cross-sectional analysis., Participants: A total of 5066 Asian participants (1367 Malays, 1772 Indians, and 1927 Chinese) from the Singapore Epidemiology of Eye Diseases Study (SEED) were included, consisting of 9594 eyes for peripapillary RNFL analysis and 8661 eyes for GCIPL analysis. Additionally, 45 064 White participants (87 649 eyes) from the United Kingdom Biobank (UKBB) were included for both macular RNFL analysis and GCIPL analysis., Methods: Nonglaucoma participants aged ≥ 40 years with complete data for estimated glomerular filtration rate (eGFR) were included from both SEED and UKBB. In SEED, peripapillary RNFL and GCIPL thickness were measured by Cirrus HD-OCT 4000. In UKBB, macular RNFL and GCIPL were measured by Topcon 3D-OCT 1000 Mark II. Chronic kidney disease was defined as eGFR < 60 ml/min/1.73 m 2 in both data sets. To evaluate the associations between kidney function status with RNFL and GCIPL thickness profiles, multivariable linear regression with generalized estimating equation models were performed in SEED and UKBB data sets separately., Main Outcome Measures: Average peripapillary and macular RNFL thickness and macular GCIPL thickness., Results: In SEED, after adjusting for age, gender, ethnicity, systolic blood pressure, antihypertensive medication, diabetes, hyperlipidemia, body mass index, smoking status, and intraocular pressure, presence of CKD (β = -1.31; 95% confidence interval [CI], -2.37 to -0.26; P  = 0.015) and reduced eGFR (per 10 ml/min/1.73 m 2 ; β = -0.32; 95% CI, -0.50 to -0.13; P  = 0.001) were associated with thinner average peripapillary RNFL. Presence of CKD (β = -1.63; 95% CI, -2.42 to -0.84) and reduced eGFR (per 10 ml/min/1.73 m 2 ; β = -0.30; 95% CI, -0.44 to -0.16) were consistently associated with thinner GCIPL in SEED (all P < 0.001). In UKBB, after adjusting for the above-mentioned covariates (except ethnicity), reduced eGFR (per 10 ml/min/1.73 m 2 ; β = -0.06; 95% CI, -0.10 to -0.01; P  = 0.008) was associated with thinner macular RNFL and CKD (β = -0.62; 95% CI, -1.16 to -0.08; P  = 0.024) was associated with thinner average GCIPL., Conclusion: We consistently observed associations between CKD and thinning of RNFL and GCIPL across Asian and White populations' eyes. These findings further suggest that compromised kidney function is associated with RNFL and GCIPL thinning., Financial Disclosures: The author(s) have no proprietary or commercial interest in any materials discussed in this article., (© 2023 by the American Academy of Ophthalmology.)

Published
2023
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