292 results on '"Choong, Yee Siew"'
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2. Application of Computational Techniques in Antibody Fc-Fused Molecule Design for Therapeutics
3. Isolation of anti-Ancylostoma-secreted protein 5 (ASP5) antibody from a naïve antibody phage library
4. A review of in vitro stochastic and non-stochastic affinity maturation strategies for phage display derived monoclonal antibodies
5. Bio-evaluation of the 2-nitrochalcones as potential anti-lung cancer agents, inducers of apoptosis and inhibitors of protein kinase (VEGFR-2)
6. Design, synthesis and evaluation of the 2′-hydroxy-3′-iodo-5′-nitrochalcones for cytotoxicity (MCF-7 & A549) and potential to inhibit tyrosine kinase (VEGFR-2) activity
7. Special issue: Biomolecular Modelling and Simulation
8. Subtractive panning for the isolation of monoclonal PEPITEM peptide antibody by phage display
9. Naïve antibody library derived monoclonal antibody against VP35 of Ebola virus
10. An in vitro study of the 5-methyl- and 5-bromo/chloro substituted 2-hydroxy-3-nitrochalcones as α-glucosidase and/or α-amylase inhibitors with potential anti-inflammatory activity
11. Antibody Phage Display
12. Antimicrobial antibodies by phage display: Identification of antibody-based inhibitor against mycobacterium tuberculosis isocitrate lyase
13. 6 In silico design of ACE2 mutants for competitive binding of SARS-CoV-2 receptor binding domain with hACE2
14. Synthesis, in vitro and in silico enzyme (COX-1/2 & LOX-5), free radical scavenging and cytotoxicity profiling of the 2,4-dicarbo substituted quinazoline 3-oxides
15. Development and structural characterisation of human scFv targeting MDM2 spliced variant MDM215kDa
16. Development of monoclonal antibodies against recombinant LipL21 protein of pathogenic Leptospira through phage display technology
17. Theoretical study of the interactions between peptide tyrosine tyrosine [PYY (1-36)], a newly identified modulator in type 2 diabetes pathophysiology, with receptors NPY1R and NPY4R
18. Molecular interaction analysis of anti-IL-8 scFv-10F8-6His against IL-8 monomer through molecular docking and molecular dynamic simulations.
19. Exploring the 3,5-Dibromo-4,6-dimethoxychalcones and Their Flavone Derivatives as Dual α-Glucosidase and α-Amylase Inhibitors with Antioxidant and Anticancer Potential.
20. Synthesis, crystal structure, cytotoxicity and evaluation of the 6-oxo-6H-pyrrolo[3,2,1-ij]quinoline-5-carbaldehydes for inhibitory effect against protein kinases (VEGFR-2 and EGFR) and cyclooxygenase-2 (COX-2) activities
21. Synthesis of furocoumarin–stilbene hybrids as potential multifunctional drugs against multiple biochemical targets associated with Alzheimer’s disease
22. Editorial: Machine Learning in Materials Science
23. The Molecular Dynamics Simulation of a Multi-domain Outer Membrane Protein A (OmpA) from Shigella flexneri in POPE Lipid Bilayer
24. Broad specificity of immune helminth scFv library to identify monoclonal antibodies targeting Strongyloides
25. DNA Switch: Toehold-Mediated DNA Isothermal Amplification for Dengue Serotyping
26. Interactions of domain antibody (dAbκ11) with Mycobacterium tuberculosis Ac2SGL in complex with CD1b
27. 2 Conformations and interactions comparison between R- and S-methadone in wild type CYP2B6, 2D6 and 3A4
28. Chemoenzymatic Bioconjugation of Antibodies: Linking Proteins for Biomedical Applications
29. Computer-Aided Antibody Design: An Overview
30. Molecular interaction analysis of anti-IL-8 scFv-10F8-6His against IL-8 monomer through molecular docking and molecular dynamic simulations
31. The design of target specific antibodies (scFv) by applying de novo workflow: Case study on BmR1 antigen from Brugia malayi
32. Demystifying the catalytic pathway of Mycobacterium tuberculosis isocitrate lyase
33. Optimisation of human VH domain antibodies specific to Mycobacterium tuberculosis heat shock protein (HSP16.3)
34. A general overview on outer membrane protein (Omp) simulations
35. Generation of a naïve human single chain variable fragment (scFv) library for the identification of monoclonal scFv against Salmonella Typhi Hemolysin E antigen
36. Construction of a Semisynthetic Human VH Single-Domain Antibody Library and Selection of Domain Antibodies against α-Crystalline of Mycobacterium tuberculosis
37. Application of streptavidin mass spectrometric immunoassay tips for immunoaffinity based antibody phage display panning
38. Molecular Dynamics Simulations in Drug Discovery
39. 2. Theoretical investigation of the derivatives of favipiravir (T-705) as potential drugs for Ebola virus
40. Structural approaches for the DNA binding motifs prediction in Bacillus thuringiensis sigma-E transcription factor (σETF)
41. Improved Fab presentation on phage surface with the use of molecular chaperone coplasmid system
42. DNA fluorescence shift sensor: A rapid method for the detection of DNA hybridization using silver nanoclusters
43. High Affinity Maturated Human Antibodies from Naïve and Synthetic Antibody Repertoires
44. Mass Spectrometry Immuno Assay (MSIA™) Streptavidin Disposable Automation Research Tips (D.A.R.T’s®) Antibody Phage Display Biopanning
45. In silico design of ACE2 mutants for competitive binding of SARS-CoV-2 receptor binding domain with hACE2.
46. Synthesis, Conformational Analysis and Evaluation of the 2-aryl-4-(4-bromo-2-hydroxyphenyl)benzo[1,5]thiazepines as Potential α-Glucosidase and/or α-Amylase Inhibitors
47. Phage display antibodies for diagnostic applications
48. Computer-Aided Antibody Design: An Overview
49. Phage Display‐Derived Antibodies: Application of Recombinant Antibodies for Diagnostics
50. Effects of Enoyl-Acyl Protein Carrier Reductase Mutations on Physiochemical Interactions with Isoniazid: Molecular Dynamics Simulation
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