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3,691 results on '"Chosidow A"'

1. Scabies

Author

Fernando, Deepani D., Mounsey, Kate E., Bernigaud, Charlotte, Surve, Nuzhat, Estrada Chávez, Guadalupe E., Hay, Roderick J., Currie, Bart J., Chosidow, Olivier, and Fischer, Katja

Published
2024
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3. Recommandations pour la pratique clinique : prévention et prise en charge de l’infection par le virus varicelle zona (VZV) pendant la grossesse et la période périnatale (version longue)

Author

Charlier, Caroline, Anselem, Olivia, Caseris, Marion, Lachâtre, Marie, Tazi, Asmaa, Driessen, Marine, Pinquier, Didier, Le Cœur, Chemsa, Saunier, Aurélie, Bergamelli, Mathilde, Vanspranghels, Roxane Gibert, Chosidow, Anaïs, Cazanave, Charles, Alain, Sophie, Faure, Karine, Birgy, André, Dubos, François, Lesprit, Philippe, Guinaud, Julie, Cohen, Robert, Decousser, Jean-Winoc, Grimprel, Emmanuel, Huissoud, Cyril, Blanc, Julie, Kayem, Gilles, Vuotto, Fanny, and Vauloup-Fellous, Christelle

Published
2025
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4. Erythema multiforme

Author

Kechichian, Elio, Dupin, Nicolas, Wetter, David A., Ortonne, Nicolas, Agbo-Godeau, Scarlette, and Chosidow, Olivier

Published
2024
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5. French protocol for the diagnosis and management of systemic lupus erythematosus

Author

Andre, Marc, Bienvenu, Boris, Blaison, Gilles, Blanco, Patrick, Cathebras, Pascal, Chauveau, Dominique, Chosidow, Olivier, Clouscard, Johanna, Deligny, Christophe, Duhaut, Pierre, Gobert, Pierre, Levesque, Hervé, Magy-Bertrand, Nadine, Melki, Isabelle, Pha, Micheline, Puechal, Xavier, Queyrel, Viviane, Raffray, Loïc, Ranchin, Bruno, Riviere, Marianne, Roblot, Pascal, Servettaz, Amelie, Amoura, Zahir, Bader-Meunier, Brigitte, Antignac, Marie, Bardin, Nathalie, Belizna, Cristina, Belot, Alexandre, Bonnotte, Bernard, Bouaziz, Jean-David, Chasset, François, Chiche, Laurent, Cohen, Fleur, Costedoat-Chalumeau, Nathalie, Daugas, Eric, Devilliers, Hervé, Diot, Elisabeth, Elefant, Elisabeth, Faguer, Stanislas, Ferreira, Nicole, Hachulla, Eric, Hanslik, Thomas, Hie, Miguel, Jourde-Chiche, Noémie, Le Guern, Véronique, Martin, Thierry, Mathian, Alexis, Michel, Marc, Miyara, Makoto, Papo, Thomas, Richez, Christophe, Scherlinger, Marc, Sibilia, Jean, Uzunhan, Yurdagul, Wahl, Denis, Wojtasik, Géraldine, and Yelnik, Cécile

Published
2024
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6. Treatment of moderate-to-severe psoriasis in adults: An expert consensus statement using a Delphi method to produce a decision-making algorithm

Author

Poizeau, F., Leducq, S., Fardet, L., Beylot-Barry, M., Chaby, Guillaume, Chastagner, M., Corgibet, F., Gouillon, L., Jouan, N., Jullien, D., Acher, A., Amatore, F., Amici, J.-M., Aubert, H., Aubin, F., Beneton, N., Bouilly, D, Bursztejn, A.-C., Buzenet, C., Chamaillard-Pujol, M., Charles, J., Cottencin-Charriere, A.-C., Duval Modeste, B., Fauconneau, A., Fougerousse, A.-C., Girard, C., Goujon, C., Khemis, A., Le Ru, Y., Lepelley-Dupont, C., Mahé, E., Marcellin, X., Nicolas, C., Pallure, V., Parier, J., Quiles, N., Stoebner, P.-E., Tauber, M., Vermersch, A., Viguier, M., Villani, A.P., Chosidow, O., and Guillot, B.

Published
2024
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7. Isotretinoin: Past, present and future. A French perspective

Author

Leducq, S., Poizeau, F., Chaby, G., Tannous, J., Ballanger-Desolneux, F., Baubion, E., Bertolotti, A., Cogrel, O., Droitcourt, C., Garnier, V., Gautier, S., Hefez, L., Hotz, C., Jonville-Béra, A.-P., Jouan, N., Mahé, A., Mahé, E., Martinho, G., Micallef, J., Puszkarek, T., Dupin, N., Ly, S., Beylot-Barry, M., Corgibet, F., Guillot, B., and Chosidow, O.

Published
2024
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8. New Treatment Solutions

Author

Bernigaud, Charlotte, Fernando, Deepani D., Fischer, Katja, Chosidow, Olivier, Fischer, Katja, editor, and Chosidow, Olivier, editor

Published
2023
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10. Prevention and management of VZV infection during pregnancy and the perinatal period

Author

Charlier, Caroline, Anselem, Olivia, Caseris, Marion, Lachâtre, Marie, Tazi, Asmaa, Driessen, Marine, Pinquier, Didier, Le Cœur, Chemsa, Saunier, Aurélie, Bergamelli, Mathilde, Gibert Vanspranghels, Roxane, Chosidow, Anaïs, Cazanave, Charles, Alain, Sophie, Faure, Karine, Birgy, André, Dubos, François, Lesprit, Philippe, Guinaud, Julie, Cohen, Robert, Decousser, Jean-Winoc, Grimprel, Emmanuel, Huissoud, Cyril, Blanc, Julie, Kayem, Gilles, Vuotto, Fanny, and Vauloup-Fellous, Christelle

Published
2024
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11. Promoting clinical research in community-based practice: Threats and opportunities

Author

Poizeau, F., Maruani, A., Staumont-Sallé, D., Jouan, N., Ly, S., Schollhammer, M., Reverte, M., Dibao-Dina, C., Duong, T.-A., Matard, B., Penso-Assathiany, D., Dupuy, A., Carriot, M., Seï, J.-F., Corgibet, F., Guillot, B., Barbarot, S., Leducq, S., Bertolotti, A., Tannous, J., Chaby, G., Jullien, D., Pépin, E., Quéreux, G., Beylot-Barry, M., and Chosidow, O.

Published
2024
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12. Promouvoir la recherche clinique en dermatologie libérale : freins et opportunités

Author

Poizeau, F., Maruani, A., Staumont-Sallé, D., Jouan, N., Ly, S., Schollhammer, M., Reverte, M., Dibao-Dina, C., Duong, T.-A., Matard, B., Penso-Assathiany, D., Dupuy, A., Carriot, M., Seï, J.-F., Corgibet, F., Guillot, B., Barbarot, S., Leducq, S., Bertolotti, A., Tannous, J., Chaby, G., Jullien, D., Pépin, E., Quéreux, G., Beylot-Barry, M., and Chosidow, O.

Published
2024
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15. Necrotizing soft tissue infections in critically ill neutropenic patients: a French multicentre retrospective cohort study

Author

Arrestier, Romain, Chaba, Anis, Mabrouki, Asma, Saccheri, Clément, Canet, Emmanuel, Pineton de Chambrun, Marc, Stoclin, Annabelle, Picard, Muriel, Wallet, Florent, Perier, François, Turpin, Matthieu, Argaud, Laurent, Decavèle, Maxens, Issa, Nahéma, Cadoz, Cyril, Klouche, Kada, Cohen, Johana, Mokart, Djamel, Grouille, Julien, Urbina, Tomas, Hua, Camille, Chosidow, Olivier, Mekontso-Dessap, Armand, Azoulay, Elie, and de Prost, Nicolas

Published
2023
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16. Isotrétinoïne : quelles actualités en dermatologie ? Conclusions du séminaire Centre de preuves en dermatologie et groupe DEFI de la SFD

Author

Leducq, S., Poizeau, F., Chaby, G., Tannous, J., Ballanger-Desolneux, F., Baubion, E., Bertolotti, A., Cogrel, O., Droitcourt, C., Garnier, V., Gautier, S., Hefez, L., Hotz, C., Jonville-Béra, A.-P., Jouan, N., Mahé, A., Mahé, E., Martinho, G., Micallef, J., Puszkarek, T., Dupin, N., Ly, S., Beylot-Barry, M., Corgibet, F., Guillot, B., and Chosidow, O.

Published
2024
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17. Low prevalence of scabies and impetigo in Dakar/Senegal: A cluster-randomised, cross-sectional survey.

Author

Andreas Hansmann, Genevia Wamba Lékémo, Chiaka Fomba, Jade Kaddoura, Ramatoullaye Toure, Assane Diop, Maodo Ndiaye, Olivier Chosidow, Michael Marks, and Fatimata Ly

Subjects
Public aspects of medicine, RA1-1270
Abstract

BackgroundScabies, a parasitic infection caused by Sarcoptes scabiei var. hominis, is a public health problem with significant morbidity worldwide, particularly in low-resource countries. Impetigo, a complication of scabies infection, is a risk factor for sepsis, glomerulonephritis and possibly acute rheumatic fever. Currently, the majority of epidemiological data has been collected in rural populations in the Pacific with limited applicability to urban populations in sub-Saharan Africa, where scabies is also believed to be a problem. To inform future public health programs, more reliable information about the burden of disease is required.Methodology/principal findingsIn July/August 2022, we conducted a cross sectional, cluster-randomised, household survey in Pikine/Dakar using the 'International Association for the Control of Scabies (IACS)' criteria to diagnose scabies and impetigo. All participants underwent a standardised clinical examination by post-graduate dermatology students. For those diagnosed with scabies, an age-adapted 'Dermatology Life Quality Index (DLQI)' questionnaire was filled. We recruited and examined 1697 participants to detect 27 cases of scabies (prevalence: 1.6%, 95% CI 0.8-3.2), mostly in school aged children. Ten participants suffered from impetigo (prevalence: 0.6%, 95% CI 0.3-1.3), 5 of which were dually infected with scabies. Risk factors for scabies infection were young age, male gender and Koranic school attendance. Of those found to have scabies, in 7 out of 22 cases (31.8%) it had a large effect on their lives according to the DLQI questionnaires filled.Conclusions/significanceThis study adds to the mapping of the burden of scabies across Africa to support public health action. With a low prevalence of scabies that is concentrated amongst poor households and children attending Koranic schools, a focused public health approach targeting Koranic schools and poor households seems to be most appropriate in this community.

Published
2024
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18. FRSign: A Large-Scale Traffic Light Dataset for Autonomous Trains

Author

Harb, Jeanine, Rébéna, Nicolas, Chosidow, Raphaël, Roblin, Grégoire, Potarusov, Roman, and Hajri, Hatem

Subjects
Computer Science - Computers and Society, Computer Science - Computer Vision and Pattern Recognition, Computer Science - Machine Learning
Abstract

In the realm of autonomous transportation, there have been many initiatives for open-sourcing self-driving cars datasets, but much less for alternative methods of transportation such as trains. In this paper, we aim to bridge the gap by introducing FRSign, a large-scale and accurate dataset for vision-based railway traffic light detection and recognition. Our recordings were made on selected running trains in France and benefited from carefully hand-labeled annotations. An illustrative dataset which corresponds to ten percent of the acquired data to date is published in open source with the paper. It contains more than 100,000 images illustrating six types of French railway traffic lights and their possible color combinations, together with the relevant information regarding their acquisition such as date, time, sensor parameters, and bounding boxes. This dataset is published in open-source at the address \url{https://frsign.irt-systemx.fr}. We compare, analyze various properties of the dataset and provide metrics to express its variability. We also discuss specific challenges and particularities related to autonomous trains in comparison to autonomous cars.

Published
2020

22. Healthcare trajectory of critically ill patients with necrotizing soft tissue infections: a multicenter retrospective cohort study using the clinical data warehouse of Greater Paris University Hospitals

Author

Camille Windsor, Camille Hua, Quentin De Roux, Anatole Harrois, Nadia Anguel, Philippe Montravers, Antoine Vieillard-Baron, Jean-Paul Mira, Tomas Urbina, Stéphane Gaudry, Matthieu Turpin, Charles Damoisel, Djillali Annane, Jean-Damien Ricard, Barbara Hersant, Armand Mekontso Dessap, Olivier Chosidow, Richard Layese, Nicolas de Prost, and AP-HP NSTI study group

Subjects
Necrotizing skin and soft tissue infections, Healthcare trajectory, NSTI, Intensive care unit, Hospital mortality, Medical emergencies. Critical care. Intensive care. First aid, RC86-88.9
Abstract

Abstract Background Necrotizing skin and soft tissue infections (NSTIs) are rare but serious and rapidly progressive infections characterized by necrosis of subcutaneous tissue, fascia and even muscle. The care pathway of patients with NSTIs is poorly understood. A better characterization of the care trajectory of these patients and a better identification of patients at risk of a complicated evolution, requiring prolonged hospitalization, multiple surgical re-interventions, or readmission to the intensive care unit (ICU), is an essential prerequisite to improve their care. The main objective of this study is to obtain large-scale data on the care pathway of these patients. We performed a retrospective multicenter observational cohort study in 13 Great Paris area hospitals, including patients hospitalized between January 1, 2015 and December 31, 2019 in the ICU for surgically confirmed NSTIs. Results 170 patients were included. The median duration of stay in ICU and hospital was 8 (3–17) and 37 (14–71) days, respectively. The median time from admission to first surgical debridement was 1 (0–2) day but 69.9% of patients were re-operated with a median of 1 (0–3) additional debridement. Inter-hospital transfer was necessary in 52.4% of patients. 80.2% of patients developed organ failures during the course of ICU stay with 51.8% of patients requiring invasive mechanical ventilation, 77.2% needing vasopressor support and 27.7% renal replacement therapy. In-ICU and in-hospital mortality rates were 21.8% and 28.8%, respectively. There was no significant difference between patients with abdomino-perineal NSTIs (n = 33) and others (n = 137) in terms of in-hospital or ICU mortality. Yet, immunocompromised patients (n = 43) showed significantly higher ICU and in-hospital mortality rates than non-immunocompromised patients (n = 127) (37.2% vs. 16.5%, p = 0.009, and 53.5% vs. 20.5%, p

Published
2022
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25. RNF213-associated urticarial lesions with hypercytokinemia

Author

Louvrier, Camille, Awad, Fawaz, Cosnes, Anne, El Khouri, Elma, Assrawi, Eman, Daskalopoulou, Aphrodite, Copin, Bruno, Bocquet, Hélène, Chantot Bastaraud, Sandra, Arenas Garcia, Angela, Dastot Le Moal, Florence, De La Grange, Pierre, Duquesnoy, Philippe, Guerrera, Chiara I., Piterboth, William, Ortonne, Nicolas, Chosidow, Olivier, Karabina, Sonia A., Amselem, Serge, and Giurgea, Irina

Published
2022
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26. Host-microbiota relationship in the pathophysiology of aseptic abscess syndrome: protocol for a multicentre case-control study (ABSCESSBIOT)

Author

Nathalie Costedoat-Chalumeau, Patrick Jégo, Nicolas Barnich, Emilie Vazeille, Maria Nachury, Marc André, Stanislas Faguer, Laurent Sailler, Bruno Pereira, Olivier Chosidow, Alexandre Thibault Jacques Maria, Jean-François Viallard, Arnaud Hot, Jean-David Bouaziz, Jérôme Connault, Jean Schmidt, Ludovic Trefond, Felix Ackermann, Fabrice Bonnet, François Lifermann, Nicolas Limal, Guillaume Cadiot, Elisabeth Billard, Richard Bonnet, Romain Altwegg, Alexandra Audemard-Verger, Damien Richard, Elisabeth Aslangul, Fairouzé Bani Sadr, Sophie Besnard, Jean-François Bourgaux, Sebastien De Almeida, Amandine Dernoncourt, Hélène Desmurs Clavel, Amelie Dutheil, Jean-Marc Galempoix, Camille Hua, Estelle Jean, Wendy Jourde, Clemence Lepelletier, Jean Benoit Monfort, Yves Poinsignon, Marie Laure Rabilloux, Jerome Razatomaery, Clea Rouillon, Mihaela Saplacan, and Laure Swiader

Subjects
Medicine
Abstract

Introduction Aseptic abscess (AA) syndrome is a rare disease whose pathophysiology is unknown. It is often associated with inflammatory bowel disease and characterised by sterile inflammation with collections of neutrophils affecting several organs, especially the spleen. Microbiota are known to influence local and systemic immune responses, and both gut and oral microbiota perturbations have been reported in diseases associated with AA syndrome. However, interactions between these factors have never been studied in AA syndrome. The purpose of this translational case-control study (ABSCESSBIOT) is to investigate gut and/or oral microbiota in patients with AA syndrome compared with healthy controls. Moreover, microbiota associated metabolites quantification and Treg/Th17 balance characterisation will give a mechanistic insight on how microbiota may be involved in the pathophysiology of AA syndrome.Methods and analysis This French multicentre case-control study including 30 French centres (University hospital or regional hospital) aims to prospectively enrol 30 patients with AA syndrome with 30 matched controls and to analyse microbiota profiling (in stools and saliva), microbial metabolites quantification in stools and circulating CD4+ T cell populations.Ethics and dissemination This study protocol was reviewed and approved by an independent French regional review board (n° 2017-A03499-44, Comité de Protection des Personnes Ile de France 1) on 10 October 2022, and declared to the competent French authority (Agence Nationale de Sécurité du Médicament et des produits de santé, France). Oral and written informed consent will be obtained from each included patient and the control participant. Study results will be reported to the scientific community at conferences and in peer-reviewed scientific journals.Trial registration number Clinical Trials web-based platform (NCT05537909).

Published
2023
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27. Hyper inflammatory syndrome following COVID-19 mRNA vaccine in children: A national post-authorization pharmacovigilance study

Author

Donzeau, Aurelie, El Aridi, Layal, Lety, Sophie, Leboucher, Bertrand, Baur, Agnes, Jeusset, Lucas, Selegny, Maelle, Fedorczuk, Cristian, Lajus, Marion, Bensaid, Philippe, Laoudi, Yacine, Pons, Charlotte, Robert, Anne-Cécile, Beaucourt, Camille, De Pontual, Loïc, Richard, Muriel, Goisque, Etienne, Iriart, Xavier, Brissaud, Olivier, Segretin, Pierre, Molimard, Julie, Orecel, Marie-Clothilde, Benoit, Gregoire, Bongiovanni, Lucille, Guerder, Margaux, Pouyau, Robin, De Guillebon De Resnes, Jean-Marie, Mezgueldi, Ellia, Cour-Andlauer, Fleur, Horvat, Come, Poinsot, Pierre, Frachette, Cecile, Ouziel, Antoine, Gillet, Yves, Barrey, Catherine, Brouard, Jacques, Villedieu, Florence, Ro, Vathanaksambath, Elanga, Narcisse, Gajdos, Vincent, Basmaci, Romain, Mutar, Hadile, Rouget, Sébastien, Nattes, Elodie, Hau, Isabelle, Biscardi, Sandra, El Jurdi, Houmam, Jung, Camille, Semama, Denis, Huet, Frederic, Zoccarato, Anne-Marie, Sarakbi, Mayssa, Mortamet, Guillaume, Bost-Bru, Cécile, Bassil, Joachim, Vinit, Caroline, Hentgen, Véronique, Leroux, Pascal, Bertrand, Valérie, Parrod, Caroline, Craiu, Irina, Kone-Paut, Isabelle, Durand, Philippe, Tissiere, Pierre, Claude, Caroline, Morelle, Guillaume, Guiddir, Tamazoust, Borocco, Charlotte, Delion, Frédérique, Guillot, Camille, Leteurtre, Stéphane, Dubos, François, Jouancastay, Mylene, Martinot, Alain, Voeusler, Valentine, Languepin, Jeanne, Garrec, Nathalie, Demersay, Arnaud Chalvon, Morand, Aurélie, Bosdure, Emmanuelle, Vanel, Noémie, Ughetto, Fabrice, Michel, Fabrice, Caujolle, Marie, Blonde, Renaud, Nguyen, Jacqueline, Vignaud, Olivier, Masserot-Lureau, Caroline, Gouraud, François, Araujo, Carine, Ingrao, Tara, Naji, Sanaa, Sehaba, Mohammed, Roche, Christine, Carbasse, Aurelia, Milesi, Christophe, Mazeghrane, Mustapha, Haupt, Sandrine, Schweitzer, Cyril, Romefort, Benedicte, Launay, Elise, Guen, Christèle Gras-Le, Ali, Ahmed, Blot, Nathalie, Tran, Antoine, Rancurel, Anne, Afanetti, Mickael, Odorico, Sophie, Talmud, Deborah, Chosidow, Anais, Romain, Anne-Sophie, Grimprel, Emmanuel, Pouletty, Marie, Gaschignard, Jean, Corseri, Olivier, Faye, Albert, Melki, Isabelle, Ducrocq, Camille, Benzoïd, Cherine, Lokmer, Johanna, Dauger, Stéphane, Chomton, Maryline, Deho, Anna, Lebourgeois, Fleur, Renolleau, Sylvain, Lesage, Fabrice, Moulin, Florence, Dupic, Laurent, Pinhas, Yael, Debray, Agathe, Chalumeau, Martin, Abadie, Véronique, Frange, Pierre, Cohen, Jeremie F, Allali, Slimane, Curtis, William, Belhadjer, Zahra, Auriau, Johanne, Méot, Mathilde, Houyel, Lucile, Bonnet, Damien, Delacourt, Christophe, Bader Meunier, Brigitte, Quartier, Pierre, Shaim, Youssef, Baril, Laurence, Crommelynck, Samuel, Jacquot, Baptiste, Blanc, Philippe, Maledon, Natacha, Robert, Blandine, Loeile, Camille, Cazau, Clémence, Loron, Gauthier, Gaga, Simona, Vittot, Cécile, El Nabhani, Loubna, Buisson, François, Prudent, Muriel, Flodrops, Hugues, Mokraoui, Fadhila, Escoda, Simon, Deschamps, Nina, Bonnemains, Laurent, Mahi, Sarah-Louisa, Mertes, Clara, Terzic, Joelle, Helms, Julie, Idier, Charlotte, Chenichene, Soraya, Magdolena Ursulescu, Nicoleta, Beaujour, Gladys, Hakim, Abdelhak, Miquel, Alice, Rey, Agnès, Wiedermann, Arnaud, Charbonneau, Anne, Veauvy-Juven, Agnès, Ferry, Alexandrine, Mandelcwajg, Alexis, Rousseau, Alix, Prenant, Amandine, Bourneuf, Anne-Laure, Filleron, Anne, Robine, Audrey, Félix, Arthur, Parizel, Aude, Labarre, Aurélie, Cantais, Aymeric, Ros, Barbara, Coulon, Basile, Biot, Blandine, Dalichoux, Bérengère, Fournier, Benjamin, Cagnard, Benoit, Vanel, Blandine, Brossier, David, Ménager, Bruno, Ozanne, Bruno, Marie-Jeanne, Carole, Bergerot, Camille, Chavy, Camille, Guidon, Camille, Fabre, Candice, Galeotti, Caroline, Baker, Catherine, Ballot-Schmit, Claire, Belleau, Céline, Charasse, Céline, Favel, Caroline, Toumi, Chadia, Ferrandiz, Charlène, Couturier, Charlotte, Pouchoux, Charlotte, Chomton-Cailliez, Maryline, Kevorkian-Verguet, Charlotte, Brunet, Clément, Manteau, Céline, Mougey, Clémence, Santy, Coline, Fitament, Coralie, Petriat, Charlotte, Rebelle, Charlotte, Charron, Cyril, Dartus, Maxime, Toulorge, David, Guillou-Debuisson, Cécile, Bartebin, Dorann, Klein, Valérie, Broustal, E, Desselas, E, Marteau, Elodie, Bouvrot, Emmanuelle, Delacroix, Elise, Coinde, Edeline, Elnabhani, Loubna, Amouyal, Elsa, Chaillou, Emilie, Gabilly-Bernard, Emeline, Ruiz, Emilie, Thibault, Emilie, Robin, Emilie, Darrieux, Etienne, Blondel, Eva, Socchi, Floriane, Cazassus, François, Bajolle, Fanny, Lacin, Fatma, Madhi, Fouad, Zekre, Franck, Guerin, François, Boussicault, Gerald, Ginies, Henri, Magloire, Gnansounou, Arnold, Guilhem, Coulognon, Ines, Sicard-Cras, Iona, Kahn, Jean-Emmanuel, Bordet, Jeanne, Fausser, Jeanne-Lise, Baleine, Jean-François, Brice, Josephine, Gendras, Julie, Pekin, Kaan, Norbert, Karine, Karsenty, Clément, Savary, Léa, Martinat, Laurence, Lesniewski, Léa, Charbonnier, Lorelei, Alexandre, Louise, Percheron, Lucas, Vincenti, Marie, Lanzini, Manon, Grisval, Margot, Mercy, Marianne, Lampin, Marie-Emilie, Desgranges, Marie, Duperril, Marie, Orcel, Marie-Clothilde, Audier, Marion, Favier, Marion, Carpentier, Mathieu, Balcean, Mathilde, Bonnet, Mathilde, Jouret, Maurine, Delattre, Marie, Levy, Michael, Valensi, Michael, Shum, Mickael, Dumortier, Morgane, Gelin, Morgane, Nemmouchi, Morgane, Williaume, Morgane, Sebaha, M, Genetay-Stanescu, Nicoleta, Giroux, Nathan, Crassard, Nicolas, Derridj, Neil, Lachaume, Noemie, Werner, Oscar, Guilluy, Olivier, Richer, Olivier, Tirel, Olivier, Pauvert, Aurianne, Casha, Paul, Perez, Noémie, Gras, Pauline, Leger, Pierre-Louis, Pinchou, Marion, Mornand, Pierre, Largo, Prisca, Ibanez, Ramona-Christina, Roulland, Charlotte, Hadah Albarazi, Salam, Bichali, Said, Faton, Sarah, Schott, Amandine, Walser, Sébastien, Guillaume, Severine, Vincent, Solene, Galene-Gromez, Sophie, Kozisek, Stanislas, Maugard, Thierry, Blanc, Thierry, Navarro, Thierry, Lauvray, Thomas, Kovacs, Tamas, Launay, Valérie, Despert, Véronique, Lhostis, Victoria, Gall, Virginie, Micaelli, Xavier, Benadjaoud, Yasmine, Matoussi, Zied, Géniaux, Hélène, Facile, Anthony, Pietri, Tessa, Palassin, Pascale, Pinel, Sylvine, Chouchana, Laurent, Callot, Delphine, Boulay, Charlène, Ouldali, Naïm, Bagheri, Haleh, Salvo, Francesco, Antona, Denise, Pariente, Antoine, Leblanc, Claire, Tebacher, Martine, Micallef, Joëlle, Levy, Corinne, Cohen, Robert, Javouhey, Etienne, Bader-Meunier, Brigitte, Ovaert, Caroline, Hentgen, Veronique, Guen, Christelle Gras-Le, Angoulvant, François, and Belot, Alexandre

Published
2022
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30. Severe Scabies: A French Multi-centre Study Involving 95 Patients with Crusted and Profuse Disease and Review of the Literature

Author

Charbel Skayem, Askour Majda, Charlotte Gary, Francois Hemery, Emmanuel Mahé, Frederic Caux, Nicolas Dupin, Patricia Senet, Alix Greder-Belan, Brigitte Hillion, Cecile Meni, Philippe Saiag, Guillaume Bellaud, Alexandre Bleibtreu, Sylvie Lariven, Diane Bollens, Vincent Descamps, Jean-Michel Molina, Olivier Bouchaud, Daniel Vittecoq, Gia Do-Pham, Francoise Foulet, Francoise Botterel, Olivier Chosidow, and Charlotte Bernigaud

Subjects
scabies, Sarcoptes scabiei, parasitic, crusted scabies, pruritus, ivermectin, Dermatology, RL1-803
Abstract

The aim of this multi-centre French retrospective study was to identify severe, i.e. crusted and profuse, scabies patients. Records were retrieved from 22 Dermatology or Infectious Diseases departments in the Ile-de-France from January 2009 to January 2015 to characterize epidemiology, demography, diagnosis, contributing factors, treatment features, and outcomes in severe scabies. A total of 95 inpatients (57 crusted and 38 profuse) were included. A higher number of cases was observed among elderly patients (>75 years), mostly living in institutions. Thirteen patients (13.6%) reported a history of previously treated scabies. Sixty-three patients (66.3%) had been seen by a previous practitioner for the current episode (up to 8 previous visits). Initial misdiagnosis (e.g. eczema, prurigo, drug-related eruptions, psoriasis) was documented in 41 patients (43.1%). Fifty-eight patients (61%) had already received 1 or more previous treatments for their current episode. Forty percent received corticosteroids or acitretin for an initial diagnosis of eczema or psoriasis. Median time from the onset of symptoms to the diagnosis of severe scabies was 3 months (range 0.3–22). Itch was present in all patients at diagnosis. Most patients (n=84, 88.4%) had comorbidities. Diagnostic and therapeutic approaches varied. Complications occurred in 11.5% of cases. To date, there is no consensus for diagnosis and treatment, and future standardization of is required for optimal management.

Published
2023
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34. Endoscopic internal drainage for the management of leak, fistula, and collection after sleeve gastrectomy: our experience in 617 consecutive patients

Author

Donatelli, Gianfranco, Spota, Andrea, Cereatti, Fabrizio, Granieri, Stefano, Dagher, Ibrahim, Chiche, Renaud, Catheline, Jean-Marc, Pourcher, Guillaume, Rebibo, Lionel, Calabrese, Daniela, Msika, Simon, Dammaro, Carmelisa, Tranchart, Hadrien, Lainas, Panagiotis, Tuszynski, Thierry, Pacini, Filippo, Arienzo, Roberto, Chevallier, Jean-Marc, Trelles, Nelson, Lazzati, Andrea, Paolino, Luca, Papini, Federica, Torcivia, Adriana, Genser, Laurent, Arapis, Kostas, Soprani, Antoine, Randone, Bruto, Chosidow, Denis, Bouillot, Jean-Luc, Marmuse, Jean-Pierre, and Dumont, Jean-Loup

Published
2021
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35. Tacrolimus 0.1% versus ciclopiroxolamine 1% for maintenance therapy in patients with severe facial seborrheic dermatitis: A multicenter, double-blind, randomized controlled study

Author

Joly, Pascal, Tejedor, Ines, Tetart, Florence, Cailleux, Hélène Collas, Barrel, Alice, De Preville, Paul Arnaud, Mion-Mouton, Nathalie, Gabison, Germaine, Baricault, Sophie, Tordeur, Catherine Girardin, Dore, Martin Xavier, Rossi, Bernard, Bourseau-Quetier, Catherine, Chamaillard, Mélanie, Ly, Sandra, Chosidow, Olivier, Richard-Lallemand, Marie-Aleth, Rzeznik, Jean-Claude, Amici, Jean-Michel, Lair, Guillaume, Bechu, Sylvie, Benichou, Jacques, Thill, Caroline, and Beylot-Barry, Marie

Published
2021
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36. Procalcitonin at 12–36 hours of fever for prediction of invasive bacterial infections in hospitalized febrile neonates

Author

Anne-Sophie Romain, Romain Guedj, Anais Chosidow, Nicolas Mediamolle, Aurélie Schnuriger, Sophie Vimont, Charlène Ferrandiz, Nicolas Robin, Marie-Hélène Odièvre, Emmanuel Grimprel, and Mathie Lorrot

Subjects
neonates, procalcitonin, invasive bacterial infection, fever, antibiotics, Pediatrics, RJ1-570
Abstract

AimWe aimed to investigate the performance of procalcitonin (PCT) assay between 12 and 36 h after onset of fever (PCT H12-H36) to predict invasive bacterial infection (IBI) (ie, meningitis and/or bacteremia) in febrile neonates.MethodsWe retrospectively included all febrile neonates hospitalized in the general pediatric department in a teaching hospital from January 2013 to December 2019. PCT assay ≤ 0.6 ng/ml was defined as negative. The primary outcome was to study the performance of PCT H12-H36 to predict IBI.ResultsOut of 385 included neonates, IBI was ascertainable for 357 neonates (92.7%). We found 16 IBI: 3 meningitis and 13 bacteremia. Sensitivity and specificity of PCT H12-H36 in the identification of IBI were, respectively, 100% [95% CI 82.9–100%] and 71.8% [95% CI 66.8–76.6%], with positive and negative predictive values of 14.3% [95% CI 8.4–22.2%] and 100% [95% CI 98.8–100%] respectively. Of the 259 neonates who had a PCT assay within the first 12 h of fever (< H12) and a PCT assay after H12-H36, 8 had IBI. Two of these 8 neonates had a negative < H12 PCT but a positive H12-H36 PCT.ConclusionsPCT H12-H36 did not miss any IBI whereas < H12 PCT could missed IBI diagnoses. PCT H12-H36 might be included in clinical decision rule to help physicians to stop early antibiotics in febrile neonates.

Published
2022
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37. Economic and disease burden of RSV-associated hospitalizations in young children in France, from 2010 through 2018

Author

C. Demont, N. Petrica, I. Bardoulat, S. Duret, L. Watier, A. Chosidow, M. Lorrot, A. Kieffer, and M. Lemaitre

Subjects
Respiratory syncytial virus, Hospitalization, Socio-economic impact, Burden, Children, Infectious and parasitic diseases, RC109-216
Abstract

Abstract Background Respiratory syncytial virus (RSV) is the main cause of infant and child hospitalizations. The study objective is to estimate the RSV-associated hospitalizations and economic burden in young children in France to inform future preventive strategies. Methods We conducted a retrospective analysis of RSV-associated hospitalizations data from the French Hospital database (PMSI-MCO) which covers the entire French population. All children aged

Published
2021
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38. Long-term quality of life in necrotizing soft-tissue infection survivors: a monocentric prospective cohort study

Author

Tomas Urbina, Florence Canoui-Poitrine, Camille Hua, Richard Layese, Aline Alves, Rachida Ouedraogo, Romain Bosc, Emilie Sbidian, Olivier Chosidow, Armand Mekontso Dessap, Nicolas de Prost, and Henri Mondor Hospital Necrotizing Fasciitis Group

Subjects
Necrotizing soft-tissue infection, Necrotizing fasciitis, Quality of life, Critical care, Septic shock, SF-36, Medical emergencies. Critical care. Intensive care. First aid, RC86-88.9
Abstract

Abstract Background Compared to other life-threatening infection survivors, long-term health-related quality of life (QOL) of patients surviving necrotizing soft-tissue infections (NSTI) and its determinants are little known. In this monocentric prospective cohort including NSTI survivors admitted between 2014 and 2017, QOL was assessed during a phone interview using the 36-Item Short-Form Health Survey (SF-36), the Hospital Anxiety and Depression (HAD), the activity of daily living (ADL), instrumental ADL (IADL) scales and the Impact of Event Scale-Revised (IES-R). The primary outcome measure was the SF-36 physical component summary (PCS). NSTI patients were compared according to intensive care unit (ICU) admission status. ICU survivors were matched on SAPS II with non-NSTI related septic shock survivors. Results Forty-nine NSTI survivors were phone-interviewed and included in the study. Median PCS was decreased compared to the reference population [− 0.97 (− 2.27; − 0.08) SD]. Previous cardiac disease was the only variable associated with PCS alteration [multivariate regression coefficient: − 8.86 (− 17.64; − 0.07), p = 0.048]. Of NSTI survivors, 15.2% had a HAD-D score ≥ 5 and 61.2% an IES-R score ≥ 33. ICU admission was not associated with lower PCS [35.21 (25.49–46.54) versus (vs) 41.82 (24.12–51.01), p = 0.516], but with higher IES-R score [14 (7.5–34) vs 7 (3–18), p = 0.035] and a higher proportion of HAD-D score ≥ 5 (28.6 vs 4.0%, p = 0.036). Compared to non-NSTI septic shock-matched controls, NSTI patients had similar PCS [33.81 (24.58; − 44.39) vs 44.87 (26.71; − 56.01), p = 0.706] but higher HAD-D [3.5 (1–7) vs 3 (1.5–6), p = 0.048] and IES-R scores [18 (8–35) vs 8 (3–19), p = 0.049]. Conclusions Long-term QOL in NSTI survivors is severely impaired, similarly to that of non-NSTI septic shock patients for physical compartments, but with more frequent depressive and/or post-traumatic stress disorders. Only ICU admission and previous cardiac disease were predictive of QOL impairment.

Published
2021
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41. Topical versus oral corticosteroids in moderate drug reaction with eosinophilia and systemic symptoms: A multicenter randomized clinical trial.

Author

Ingen-Housz-Oro, Saskia, Guichard, Elie, Milpied, Brigitte, Bensaid, Benoit, Collet, Evelyne, Barbaud, Annick, Le Duff, Florence, Tétart, Florence, Soria, Angèle, Machet, Laurent, Descamps, Vincent, Monestier, Sandrine, Pasteur, Justine, Morice, Cécile, Chaby, Guillaume, Colin, Audrey, Grégoire, Laëtitia, Allanore, Laurence, Giraudeau, Bruno, and Chosidow, Olivier

Published
2024
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43. Diagnostics to support the control of scabies-Development of two target product profiles.

Author

Michael Marks, Jodie McVernon, James S McCarthy, Wendemagegn Enbiale, Christopher Hanna, Olivier Chosidow, Daniel Engelman, Kingsley Asiedu, and Andrew Steer

Subjects
Arctic medicine. Tropical medicine, RC955-962, Public aspects of medicine, RA1-1270
Abstract

BackgroundScabies was added to the WHO NTD portfolio in 2017 and targets for the control of scabies were included in the 2021-2030 WHO NTD roadmap. A major component of scabies control efforts a strategy based on mass drug administration (MDA) with ivermectin. Currently diagnosis of scabies relies on clinical examination with a limited role for diagnostic testing. Under the recommendation of the WHO Diagnostic Technical Advisory Group (DTAG) for Neglected Tropical Diseases, a working group was assembled and tasked with agreeing on priority use cases for and developing target product profiles (TPPs) for new diagnostics tools for scabies.Methodology and principal findingsThe working group convened three times and established two use cases: establishing if the 10% threshold for mass drug administration had been reached and if the 2% threshold for stopping mass drug administration has been achieved. One subgroup assessed the current diagnostic landscape for scabies and a second subgroup determined the test requirements for both use cases. Draft TPPs were sent out for input from stakeholders and experts. Both TPPs considered the following parameters: product use, design, performance, configuration, cost, access and equity. The group considered the use of the tests as a single step process or as part of a two step process following initial clinical examination. When used a single step test (the ideal scenario) for starting MDA a new diagnostic required a sensitivity of ≥92% and a specificity of ≥98%. When used a single step test (the ideal scenario) for stopping MDA a new diagnostic required a sensitivity of ≥80% and a specificity of ≥99%.ConclusionsThe TPPs developed will provide test developers with guidance to ensure that novel diagnostic tests meet identified public health needs.

Published
2022
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44. Impact of Childhood Onset Psoriasis on Addictive Behaviours, Socioeconomic and Educational Data in Adulthood

Author

Emmanuel Mahé, Florence Tubach, Denis Jullien, Diep Tran, Carle Paul, Marie Beylot-Barry, Alain Dupuy, Manuelle Viguier, Marie-Aleth Richard, Emilie Sbidian, Nathalie Beneton, Pascal Joly, Olivier Chosidow, and Hervé Bachelez

Subjects
psoriasis, children, adolescent, socioeconomic data, educational level, alcohol, Dermatology, RL1-803
Abstract

Paediatric psoriasis has been associated with school absenteeism, limitation of physical activities, psychiatric disorders and, in the longer term, with sexual dysfunction and addictions. This raises the hypothesis that childhood onset psoriasis may affect patients’ educational development, and further social and professional outcomes. This study evaluated the relationship between childhood onset psoriasis and patients’ educational and socioeconomic characteristics, and the development of addictions in adulthood. This cross-sectional ancillary study captured patients’ characteristics at baseline in the French PSOBIOTEQ registry. Data in adulthood included: educational (baccalaureate) and socioeconomic (working activity) groups, smoking status (self-reporting of being a current smoker vs past smoker or non-smoker), alcohol consumption (defined as at least 1 glass of alcoholic beverage per day), and living conditions (alone/family/social institutions; child at home). A total of 1,960 patients were included, of whom 26.2% had childhood onset psoriasis. In multivariate analyses, childhood onset psoriasis was associated with smoker status (p = 0.02). No association was observed with educational level, working activity, living conditions, or alcohol consumption. This study provides reassuring data overall with regard to the impact of childhood onset psoriasis on major social outcomes. Evidence for some association with addictive behaviours paves the way for larger prospective studies assessing in depth the social and educational impact of this disease.

Published
2022
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48. Arthropods

Author

Bernigaud, Charlotte, primary, Monsel, Gentiane, additional, Delaunay, Pascal, additional, and Chosidow, Olivier, additional

Published
2024
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