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768 results on '"Chow, Wah"'

1. Interventions to improve health care provider implementation and patient adherence of patients to recommendations on geriatric assessment and management in older adults: A scoping review protocol.

Author

Laura Freeman, Ainslee Smith, Nai-Wen Ku, Ana Patricia Ayala, Fay Bennie, Arielle Berger, Tyler R Chesney, Ploa Desforges, Kristen Haase, Jennifer Jones, Annie Lacerte, Caroline Mariano, Rajin Mehta, Ines Menjak, Johanne Monette, Richard Norman, Nicholas Legacy, Maryjo Antonio, Eric Pitters, Anne Stephens, Douglas Stephens, Doreen Wan-Chow-Wah, Camilla L Wong, Shabbir M H Alibhai, and Martine Puts

Subjects
Medicine, Science
Abstract

The world population is aging. Comprehensive Geriatric assessment (CGA) has been proven to improve the well-being of older adults. However, evidence suggests not all clinicians implement these recommendations in their practice; nor do all patients adhere to them. Currently, there is no up-to-date review of interventions that can improve older adults' adherence to CGA recommendations and health care provider/clinician implementation of those recommendations. The objective of this scoping review protocol is to describe the methodology of the scoping review with the aim to identify interventions that have been tested to improve adherence to CGA recommendations. We will use the Arksey and O'Malley framework and subsequent extension by Levac and colleagues to complete the scoping review. We searched OVID MEDLINE, OVID Embase, EBSCO CINAHL, APA PsychInfo, and Cochrane CENTRAL databases from inception to November 14, 2024, and will include a review of reference lists of included studies. Studies eligible for inclusion are studies of any design that examined one or more interventions aiming to improve clinician implementation of and patient adherence to CGA in any clinical setting. We will use standard methods for study selection, data abstraction, assessment of methodological quality of individual studies, and data synthesis. Results will be analyzed and reported using descriptive numerical summaries and narrative analysis. Findings from the scoping review will be published in a manuscript and presented at scientific conferences.

Published
2025
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2. Implementing geriatric assessment and management for older Canadians with cancer: Adherence to and satisfaction with the intervention, results of the 5C study

Author

Puts, Martine, Waked, Jihad Abou Ali, Strohschein, Fay, Breunis, Henriette, Alqurini, Naser, Berger, Arielle, Romanovsky, Lindy, Monette, Johanne, Mehta, Rajin, Li, Anson, Wan-Chow-Wah, Doreen, Koneru, Rama, Szumacher, Ewa, Mariano, Caroline, Hsu, Tina, Brennenstuhl, Sarah, Amir, Eitan, Krzyzanowska, Monika K., Jang, Raymond, Pitters, Eric, Emmenegger, Urban, Menjak, Ines B., Bergman, Simon, Lemonde, Manon, Beland, Francois, and Alibhai, Shabbir M.H.

Published
2023
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13. Efficacy of immune checkpoint inhibitors in older patients with non-small cell lung cancer: Real-world data from multicentric cohorts in Canada and France

Author

Elkrief, Arielle, Richard, Corentin, Malo, Julie, Cvetkovic, Lena, Florescu, Marie, Blais, Normand, Tehfe, Mustapha, Messaoudene, Meriem, Gagné, Andréanne, Orain, Michele, Medjebar, Soleine, Wan-Chow-Wah, Doreen, Joubert, Philippe, Labbé, Catherine, Ghiringhelli, Francois, and Routy, Bertrand

Published
2020
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39. Impact of Geriatric Assessment and Management on Quality of Life, Unplanned Hospitalizations, Toxicity, and Survival for Older Adults With Cancer: The Randomized 5C Trial

Author

Puts, Martine, primary, Alqurini, Naser, additional, Strohschein, Fay, additional, Koneru, Rama, additional, Szumacher, Ewa, additional, Mariano, Caroline, additional, Monette, Johanne, additional, Hsu, Tina, additional, Brennenstuhl, Sarah, additional, McLean, Bianca, additional, Wills, Aria, additional, Berger, Arielle, additional, Amir, Eitan, additional, Romanovsky, Lindy, additional, Li, Anson, additional, Mehta, Rajin, additional, Krzyzanowska, Monika, additional, Elser, Christine, additional, Jang, Raymond, additional, Prica, Anca, additional, Wan-Chow-Wah, Doreen, additional, Pitters, Eric, additional, Emmenegger, Urban, additional, Menjak, Ines B., additional, Bergman, Simon, additional, Lemonde, Manon, additional, Breunis, Henriette, additional, Béland, Francois, additional, and Alibhai, Shabbir M.H., additional

Published
2023
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46. Impact of Geriatric Assessment and Management on Quality of Life, Unplanned Hospitalizations, Toxicity, and Survival for Older Adults With Cancer: The Randomized 5C Trial

Author

Martine Puts, Naser Alqurini, Fay Strohschein, Rama Koneru, Ewa Szumacher, Caroline Mariano, Johanne Monette, Tina Hsu, Sarah Brennenstuhl, Bianca McLean, Aria Wills, Arielle Berger, Eitan Amir, Lindy Romanovsky, Anson Li, Rajin Mehta, Monika Krzyzanowska, Christine Elser, Raymond Jang, Anca Prica, Doreen Wan-Chow-Wah, Eric Pitters, Urban Emmenegger, Ines B. Menjak, Simon Bergman, Manon Lemonde, Henriette Breunis, Francois Béland, and Shabbir M.H. Alibhai

Subjects
Cancer Research, Oncology
Abstract

PURPOSE American Society of Clinical Oncology recommends that older adults with cancer being considered for chemotherapy receive geriatric assessment (GA) and management (GAM), but few randomized controlled trials have examined its impact on quality of life (QOL). PATIENTS AND METHODS The 5C study was a two-group parallel 1:1 single-blind multicenter randomized controlled trial of GAM for 6 months versus usual oncologic care. Eligible patients were age 70+ years, diagnosed with a solid tumor, lymphoma, or myeloma, referred for first-/second-line chemotherapy or immunotherapy or targeted therapy, and had an Eastern Cooperative Oncology Group performance status of 0-2. The primary outcome QOL was measured with the global health scale of the European Organisation for the Research and Treatment of Cancer QOL questionnaire and analyzed with a pattern mixture model using an intent-to-treat approach (at 6 and 12 months). Secondary outcomes included functional status, grade 3-5 treatment toxicity; health care use; satisfaction; cancer treatment plan modification; and overall survival. RESULTS From March 2018 to March 2020, 350 participants were enrolled. Mean age was 76 years and 40.3% were female. Fifty-four percent started treatment with palliative intent. Eighty-one (23.1%) patients died. GAM did not improve QOL (global QOL of 4.4 points [95% CI, 0.9 to 8.0] favoring the control arm). There was also no difference in survival, change in treatment plan, unplanned hospitalization/emergency department visits, and treatment toxicity between groups. CONCLUSION GAM did not improve QOL. Most intervention group participants received GA on or after treatment initiation per patient request. Considering recent completed trials, GA may have benefit if completed before treatment selection. The COVID-19 pandemic may have affected our QOL outcome and intervention delivery for some participants.

Published
2022

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