121 results on '"Christiane Scheffler"'
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2. Networks in Auxology – proceedings of the 31st Aschauer Soiree, held at Aschau, Germany, June 17th 2023
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Michael Hermanussen, Christiane Scheffler, Melanie Dammhahn, Detlef Groth, Cédric Moris, Tim Hake, Barry Bogin, Piotr Fedurek, Jesper Boldsen, Takashi Satake, Stef van Buuren, Jani Söderhäll, Chris Jefferies, Yehuda Limony, Jovanna Dahlgren, Julia Quitmann, Ingo Scheffler, Nino Nazirishvili, Ekaterine Kvaratskhelia, Annamaria Zsakai, Martin Musalek, Basak Koca Özer, Cansev Meşe Yavuz, Janina Tutkuviene, Laura Kasperiunaite, Simona Gervickaite, Sylvia Kirchengast, Slawomir Koziel, Aleksandra Gomula, Zbyszek Czapla, Antonia Rösler, Leslie Lieberman, Stephen Lieberman, and Martin Brüne
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Social hierarchies ,strategic growth adjustment ,Monte Carlo analysis ,life history strategy ,adherence and quality of life ,Medicine ,Biology (General) ,QH301-705.5 - Abstract
Twenty-seven scientists met for the annual Auxological conference held at Aschau, Germany, to particularly discuss the interaction between social factors and human growth, and to highlight several topics of general interest to the regulation of human growth. Humans are social mammals. Humans show and share personal interests and needs, and are able to strategically adjust size according to social position, with love and hope being prime factors in the regulation of growth. In contrast to Western societies, where body size has been shown to be an important predictor of socioeconomic status, egalitarian societies without formalized hierarchy and material wealth-dependent social status do not appear to similarly integrate body size and social network. Social network structures can be modeled by Monte Carlo simulation. Modeling dominance hierarchies suggests that winner-loser effects play a pivotal role in robust self-organization that transcends the specifics of the individual. Further improvements of the St. Nicolas House analysis using re-sampling/bootstrap techniques yielded encouraging results for exploring dense networks of interacting variables. Customized pediatric growth references, and approaches towards a Digital Rare Disease Growth Chart Library were presented. First attempts with a mobile phone application were presented to investigate the associations between maternal pre-pregnancy overweight, gestational weight gain, and the child’s future motor development. Clinical contributions included growth patterns of individuals with Silver-Russell syndrome, and treatment burden in children with growth hormone deficiency. Contributions on sports highlighted the fallacy inherent in disregarding the biological maturation status when interpreting physical performance outcomes. The meeting explored the complex influence of nutrition and lifestyle on menarcheal age of Lithuanian girls and emphasized regional trends in height of Austrian recruits. Examples of the psychosocial stress caused by the forced migration of modern Kyrgyz children and Polish children after World War II were presented, as well as the effects of nutritional stress during and after World War I. The session concluded with a discussion of recent trends in gun violence affecting children and adolescents in the United States, and aspects of life history theory using the example of "Borderline Personality Disorder." The features of this disorder are consistent with the notion that it reflects a "fast" life history strategy, with higher levels of allostatic load, higher levels of aggression, and greater exposure to both childhood adversity and chronic stress. The results were discussed in light of evolutionary guided research. In all contributions presented here, written informed consent was obtained from all participants in accordance with institutional Human investigation committee guidelines in accordance with the Declaration of Helsinki amended October 2013, after information about the procedures used.
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- 2023
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3. Attitude towards purchasing consumer items can be extracted from Demographic and health survey India-2019-2020 (NFHS 5)
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Singha Roy Soumyajit, Mithun Sikdar, Nitish Mondal, Christiane Scheffler, Detlef Groth, and Michael Hermanussen
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consumer items ,national health surveys ,associated chains ,gross domestic production ,antropometry ,Medicine ,Biology (General) ,QH301-705.5 - Abstract
Background: National Health Surveys have been part of national health services in many countries, but their data are summary com- pilations and commonly used only for describing trends in health and living conditions. Aim: Tostatisticallydisclosenetworksofinteractingvariableswithin National Health Survey data. Sample and methods: We used anthropometric, educational, environ- mental and economic information of people of Sikkim, West Bengal, Telangana, and Gujarat, India, obtained by the Fifth Indian National Family Health Survey (NFHS-5). We applied a new statistical approach labeled as “St. Nicholas House Analysis” (SNHA). SNHA ranks absolute bivariate correlation coef- ficients in descending order according to magnitude. The method creates hierarchic “association chains” of correlation coefficients de- fined by sequences where reversing the start and end point does not alter the ordering of elements. Association chains characterize de- pendence structures within networks of extensively interacting variables. Results: SNHA disclosed fundamental differences in the network of anthropometric, educational, environmental and economic variables of the people of Sikkim, and the people of West Ben- gal, Telangana and Gujarat. Whereas relevant interactions among these variables were largely absent in the people of Sikkim, the variables formed characteristic star-shaped networks with wealth quintile and the possession of motorcycles in a strong central position, in the people of West Bengal, Telangana and Gujarat. Conclusion: Depicting association chains within net- works of extensively interacting variables such as health survey data appears to be a promising statisti- cal tool for disentangling the effects of environmen- tal circumstances, education, and social, economic, political and emotional (SEPE) factors on human growth.
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- 2023
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4. First osteological evidence of severed hands in Ancient Egypt
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Julia Gresky, Manfred Bietak, Emmanuele Petiti, Christiane Scheffler, and Michael Schultz
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Medicine ,Science - Abstract
Abstract For the first time, the severed right hands of 12 individuals have been analysed osteologically. The hands were deposited in three pits within a courtyard in front of the throne room of a 15th Dynasty (c.1640–1530 BC) Hyksos palace at Avaris/Tell el-Dab‘a in north-eastern Egypt. Although this kind of practice is known from tomb or temple inscriptions and reliefs from the New Kingdom onwards, this is the first time that physical evidence has been used to learn more about the procedure and the individuals whose hands were taken. Here, we show that the right hands belonged to at least 12 adults, 11 males, and possibly one female. It is unclear if the hands were taken from dead or living individuals. After removing any attached parts of the forearm, the hands were placed in the ground with wide-splayed fingers, mainly on their palmar sides. The osteological analysis not only supports the archaeological interpretation of this evidence but also adds more detail regarding trophy-taking practices in Ancient Egypt.
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- 2023
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5. Environment, social behavior, and growth
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Michael Hermanussen, Christiane Scheffler, Aman Pulungan, Arup Ratan Bandyopadhyay, Jyoti Ratan Ghosh, Ayşegül Özdemir, Başak Koca Özer, Martin Musalek, Lidia Lebedeva, Elena Godina, Barry Bogin, Janina Tutkuviene, Milda Budrytė, Simona Gervickaite, Yehuda Limony, Sylvia Kirchengast, Peter Buston, Detlef Groth, Antonia Rösler, Nikolaos Gasparatos, Sergei Erofeev, Masiar Novine, Bárbara Navazo, Silvia Dahinten, Aleksandra Gomuła, Natalia Nowak-Szczepańska, and Sławomir Kozieł
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St. Nicolas House Analysis ,child growth ,body proportions ,social network ,public health ,migration ,Medicine ,Biology (General) ,QH301-705.5 - Abstract
Twenty-four scientists met for the annual Auxological conference held at Krobielowice castle, Poland, to discuss the diverse influences of the environment and of social behavior on growth following last year’s focus on growth and public health concerns (Hermanussen et al., 2022b). Growth and final body size exhibit marked plastic responses to ecological conditions. Among the shortest are the pygmoid people of Rampasasa, Flores, Indonesia, who still live under most secluded insular conditions. Genetics and nutrition are usually considered responsible for the poor growth in many parts of this world, but evidence is accumulating on the prominent impact of social embedding on child growth. Secular trends not only in the growth of height, but also in body proportions, accompany the secular changes in the social, economic and political conditions, with major influences on the emotional and educational circumstances under which the children grow up (Bogin, 2021). Aspects of developmental tempo and aspects of sports were discussed, and the impact of migration by the example of women from Bangladesh who grew up in the UK. Child growth was considered in particular from the point of view of strategic adjustments of individual size within the network of its social group. Theoretical considerations on network characteristics were presented and related to the evolutionary conservation of growth regulating hypothalamic neuropeptides that have been shown to link behavior and physical growth in the vertebrate species. New statistical approaches were presented for the evaluation of short term growth measurements that permit monitoring child growth at intervals of a few days and weeks.
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- 2023
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6. Human growth data analysis and statistics – the 5th Gülpe International Student Summer School
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Detlef Groth, Christiane Scheffler, and Michael Hermanussen
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Summer Schools ,Statistical Exercise ,Repetition ,Medicine ,Biology (General) ,QH301-705.5 - Abstract
The Summer School in Gülpe (Ecological Station of the University of Potsdam) offers an exceptional learning opportunity for students to apply their knowledge and skills to real-world problems. With the guidance of experienced human biologists, statisticians, and programmers, students have the unique chance to analyze their own data and gain valuable insights. This interdisciplinary setting not only bridges different research areas but also leads to highly valuable outputs. The progress of students within just a few days is truly remarkable, especially when they are motivated and receive immediate feedback on their questions, problems, and results. The Summer School covers a wide range of topics, with this year’s focus mainly on two areas: understanding the impact of socioeconomic and physiological factors on human development and mastering statistical techniques for analyzing data such as changepoint analysis and the St. Nicolas House Analysis (SNHA) to visualize interacting variables. The latter technique, born out of the Summer School’s emphasis on gaining comprehensive data insights and understanding major relationships, has proven to be a valuable tool for researchers in the field. The articles in this special issue demonstrate that the Summer School in Gülpe stands as a testament to the power of practical learning and collaboration. Students who attend not only gain hands-on experience but also benefit from the expertise of professionals and the opportunity to engage with peers from diverse disciplines.
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- 2023
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7. No evidence of growth impairment after forced migration in Polish school children after World War II
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Antonia Rösler, Christiane Scheffler, and Michael Hermanussen
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nutrition ,stunting ,socioeconomy ,education ,secular changes ,pubertal timing ,Medicine ,Biology (General) ,QH301-705.5 - Abstract
Background: Migration is omnipresent. It can come hand in hand with emotional stress which is known to influence the growth of children. Objective: The aim of this study was to analyse whether type of migration (forced or voluntary) and the geographic direction had influenced the growth of Polish children after World War II. Sample and Methods: A sub dataset of 2,208 individuals between the ages of 2-20, created from data of the 2nd Polish Anthropological Survey carried out in 1966–1969, including anthropometrical data and social and demographic information based on questionnaire, was used to analyse migration effects. Results: No association could be found between the direction of migration and the height of the children. The confidence intervals of the means of all classified migration categories overlap significantly and the effect size of the influence of migration category on height is ds=.140, which is too low to see any effects, even if there were one. Conclusion: Neither forced nor voluntary migration in Poland after World War II led to a change in height in children of migrating families.
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- 2023
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8. Assessing the applicability of changepoint analysis to analyse short-term growth
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Nikolaos Gasparatos, Christiane Scheffler, and Michael Hermanussen
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changepoint analysis ,changepoint detection ,performance evaluation ,mini growth spurt ,short-term growth ,Medicine ,Biology (General) ,QH301-705.5 - Abstract
Background: Assessing short-term growth in humans is still fraught with difficulties. Especially when looking for small variations and increments, such as mini growth spurts, high precision instruments or frequent measurements are necessary. Daily measurements however require a lot of effort, both for anthropologists and for the subjects. Therefore, new sophisticated approaches are needed that reduce fluctuations and reveal underlying patterns. Objectives: Changepoints are abrupt variations in the properties of time series data. In the context of growth, such variations could be variation in mean height. By adjusting the variance and using different growth models, we assessed the ability of changepoint analysis to analyse short-term growth and detect mini growth spurts. Sample and Methods: We performed Bayesian changepoint analysis on simulated growth data using the bcp package in R. Simulated growth patterns included stasis, linear growth, catch-up growth, and mini growth spurts. Specificity and a normalised variant of the Matthews correlation coefficient (MCC) were used to assess the algorithm’s performance. Welch’s t-test was used to compare differences of the mean. Results: First results show that changepoint analysis can detect mini growth spurts. However, the ability to detect mini growth spurts is highly dependent on measurement error. Data preparation, such as ranking and rotating time series data, showed negligible improvements. Missing data was an issue and may affect the prediction quality of the classification metrics. Conclusion: Changepoint analysis is a promising tool to analyse short-term growth. However, further optimisation and analysis of real growth data is needed to make broader generalisations.
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- 2023
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9. Nutrition, size, and tempo
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Michael Hermanussen and Christiane Scheffler
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food access ,physical time ,SEPS factors ,pace of life ,catch-up-growth ,Medicine ,Biology (General) ,QH301-705.5 - Abstract
Nutrition is a prerequisite, but not a regulator of growth. Growth is defined as increase in size over time. The understanding of growth includes an understanding of the binary concept of physical time and individual tempo. Excess food causes tempo acceleration. Food restriction delays tempo. Tempo reflects the pace of life. It is a dynamic physical response to a broad spectrum of social, economic, political, and emotional (SEPE) factors and can affect life expectancy. Variations in tempo create distortions of the z-score patterns of height and weight. Illness or intermediate food shortage lead to intermediate halts in development and create short dips in the z-score patterns. Children who develop throughout life at delayed pace usually run at lower z-scores for height and weight, and show a characteristic adolescent trough; children who develop throughout life at faster than average pace usually run at higher z-scores and show a characteristic adolescent peak in their z-score patterns. During adolescence, almost half of the height variance is due to tempo variation. There is not one tempo for the whole body. Different organ systems grow and mature at different pace.
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- 2023
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10. What does stunting tell us?
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Christiane Scheffler and Michael Hermanussen
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SEPE Factors ,physical fitness ,height in history ,malnutrition ,Medicine ,Biology (General) ,QH301-705.5 - Abstract
Stunting is commonly linked with undernutrition. Yet, already after World War I, German pediatricians questioned this link and stated that no association exists between nutrition and height. Recent analyses within different populations of Low- and middle-income countries with high rates of stunted children failed to support the assumption that stunted children have a low BMI and skinfold sickness as signs of severe caloric deficiency. So, stunting is not a synonym of malnutrition. Parental education level has a positive influence on body height in stunted populations, e.g., in India and in Indonesia. Socially disadvantaged children tend to be shorter and lighter than children from affluent families. Humans are social mammals; they regulate growth similar to other social mammals. Also in humans, body height is strongly associated with the position within the social hierarchy, reflecting the personal and group-specific social, economic, political, and emotional environment. These non-nutritional impact factors on growth are summarized by the concept of SEPE (Social-Economic-Political-Emotional) factors. SEPE reflects on prestige, dominance-subordination, social identity, and ego motivation of individuals and social groups.
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- 2023
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11. Bergmann’s rule is a 'just-so' story of human body size
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Barry Bogin, Michael Hermanussen, and Christiane Scheffler
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Developmental plasticity ,SEPE ,Body size ,Body shape ,Physical anthropology. Somatology ,GN49-298 - Abstract
Abstract Carl Bergmann was an astute naturalist and physiologist. His ideas about animal size and shape were important advances in the pre-Darwinian nineteenth century. Bergmann’s rule claims that that in cold climates, large body mass increases the ratio of volume-to-surface area and provides for maximum metabolic heat retention in mammals and birds. Conversely, in warmer temperatures, smaller body mass increases surface area relative to volume and allows for greater heat loss. For humans, we now know that body size and shape are regulated more by social-economic-political-emotional (SEPE) factors as well as nutrition-infection interactions. Temperature has virtually no effect. Bergmann’s rule is a “just-so” story and should be relegated to teaching and scholarship about the history of science. That “rule” is no longer acceptable science and has nothing to tell us about physiological anthropology.
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- 2022
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12. Locally structured correlation (LSC) plots describe inhomogeneity in normally distributed correlated bivariate variables
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Rebekka Mumm, Christiane Scheffler, and Michael Hermanussen
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Standard deviation ,Locally structured standard deviation ,Locally structured correlation ,Variance ,Public aspects of medicine ,RA1-1270 - Abstract
Abstract Background The association between bivariate variables may not necessarily be homogeneous throughout the whole range of the variables. We present a new technique to describe inhomogeneity in the association of bivariate variables. Methods We consider the correlation of two normally distributed random variables. The 45° diagonal through the origin of coordinates represents the line on which all points would lie if the two variables completely agreed. If the two variables do not completely agree, the points will scatter on both sides of the diagonal and form a cloud. In case of a high association between the variables, the band width of this cloud will be narrow, in case of a low association, the band width will be wide. The band width directly relates to the magnitude of the correlation coefficient. We then determine the Euclidean distances between the diagonal and each point of the bivariate correlation, and rotate the coordinate system clockwise by 45°. The standard deviation of all Euclidean distances, named “global standard deviation”, reflects the band width of all points along the former diagonal. Calculating moving averages of the standard deviation along the former diagonal results in “locally structured standard deviations” and reflect patterns of “locally structured correlations (LSC)”. LSC highlight inhomogeneity of bivariate correlations. We exemplify this technique by analyzing the association between body mass index (BMI) and hip circumference (HC) in 6313 healthy East German adults aged 18 to 70 years. Results The correlation between BMI and HC in healthy adults is not homogeneous. LSC is able to identify regions where the predictive power of the bivariate correlation between BMI and HC increases or decreases, and highlights in our example that slim people have a higher association between BMI and HC than obese people. Conclusion Locally structured correlations (LSC) identify regions of higher or lower than average correlation between two normally distributed variables.
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- 2022
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13. Practicability and user-friendliness of height measurements by proof of concept APP using Augmented Reality, in 22 healthy children
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Antonia Rösler, Nikolaos Gasparatos, Michael Hermanussen, and Christiane Scheffler
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body height ,guideline ,augmented reality ,daily home-made measurements ,iPhone ,APP ,Medicine ,Biology (General) ,QH301-705.5 - Abstract
Background: Child growth is a dynamic process. When measured at short intervals, children’s growth shows characteristic patterns that can be of great importance for clinical purposes. Objective: To study whether measuring height on a daily basis using an APP is practicable and user-friendly. Methods: Recruitment took place via Snowball Sampling. Thirteen out of 14 contacted families signed up for a study period of 12 weeks with altogether 22 healthy children aged 3 to 13 years (response rate 93%). The study started with a visit to the family home for the setup of the measurement site, conventional height measuring and initial training of the new measurement process. Follow-up appointments were made at four, eight and 12 weeks. The children’s height was measured at daily intervals at their family homes over a period of three months. Results: The parents altogether recorded 1704 height measurements and meticulously documented practicability and problems when using the device. A 93% response rate in recruitment was achieved by maintaining a high motivation within the families. Contact with the principal investigator was permanently available, including open communication, personal training and attendance during the appointments at the family homes. Conclusion: Measuring height by photographic display is interesting for children and parents and can be used for height measurements at home. A positive response rate of 13 out of 14 families with altogether 22 children highlights feasible recruitment and the high convenience and user-friendliness of daily APP-supported height measurements. Daily APP measurements appear to be a promising new tool for longitudinal growth studies.
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- 2022
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14. Growth and Public Health Concerns
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Michael Hermanussen, Christiane Scheffler, Liza Wilke, Sonja Böker, Detlef Groth, Sylvia Kirchengast, Dominik Hagmann, Lidia Lebedeva, Elena Godina, Aleksandra Gomula, Jan M Konarski, Ayşegül Özdemir Başaran, Başak Koca Özer, Janina Tutkuviene, Simona Gervickaite, Dziugile Kersnauskaite, and Slawomir Koziel
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dominance ,prestige ,nutrition ,spatial difference ,developmental tempo ,Medicine ,Biology (General) ,QH301-705.5 - Abstract
Seventeen scientists met for this year’s conference on Auxology held at Krobielowice castle, Poland, to discuss growth and public health concerns. The regulation of growth is complex and besides metabolic and endocrine components including hypothalamic releasing factors, growth hormone and multiple downstream effectors, comprises the full spectrum of the psychosocial, economic and emotional environment including signaling dominance, competence, prestige, or subordination and indulgence, all of this being sensitive to urban or rural lifestyle, the political climate and with marked plasticity throughout history. New statistical techniques (St. Nicolas House Analysis) are presented for analyzing anthropometric variables for public health concerns. The impact of spatial differences on developmental tempo, growth in height, and the prevalence of childhood obesity are discussed as well as the impact of social mobility on obesity, and the benefits of the biopsychosocial status when getting along with socio-economic disasters and the COVID-19 pandemic.
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- 2022
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15. No association between body height and metabolic risk factors in historically short height Asian Indian tribes
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Binu Dorjee, Jaydip Sen, Mithun Das, Kaushik Bose, Christiane Scheffler, and Gautam Kumar Kshatriya
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Height ,India ,Tribes ,Diabetes ,Hypertension ,St. Nicolas House Analysis ,Medicine ,Biology (General) ,QH301-705.5 - Abstract
Background: Asian Indians often get predisposed to non-communicable diseases for which the “thin-fat” or “hidden obese” Indian phenotype is usually regarded responsible. In Europe, America and in some low-middle-income countries (LMICs) short height is often associated with a high risk of metabolic syndrome (MetS). Indians and particularly tribal Indian people are relatively short. Aim: To assess the associations of height with MetS risk factors among tribal people of India. Sample and methods: This study was conducted among tribes of India under life-style transition. The height range was 163.2 cm to 156.5 cm (males) and 151.6 cm to 146.9 cm (females). The participants were 1066 men and 1090 women aged 20 to 60 years. Anthropometric and metabolic markers included in the study were height, body mass index (BMI), waist circumference (WC), skinfolds (biceps, triceps, sub-scapular, and supra-iliacal), fasting blood glucose (FBG), blood pressure (systolic and diastolic) and pulse rate (PR). Results: The highest correlation existed between height and WC (male: 0.21; female: 0.15). Correlations of body composition variables (BMI, WC, skinfolds) with MetS risk factors (FBG, SBP, DBP, PR) were not reliable (r < 0.30) among both sexes. St. Nicolas House Analysis revealed WC among males and WC and sub-scapular skinfolds among females sharing more connections with other nodes variables. Conclusions: Unlike the people of the wealthy and often obese social strata of low-middle-income countries, and in Europe and North America, height of tribal Indian populations is not associated with metabolic risk factors, such as hypertension, elevated fasting blood sugar, and central obesity. Rather than linked to the phenotype, obesity appears to be associated with an obesogenic environment. Public health policy should focus on problems associated with obesogenic environments.
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- 2022
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16. The arithmetic dilemma when defining thinness, overweight and obesity in stunted populations
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Michael Hermanussen, Masiar Novine, Christiane Scheffler, and Detlef Groth
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BMI ,stunting ,prevalence ,thinness ,obesity ,misclassification ,Medicine ,Biology (General) ,QH301-705.5 - Abstract
Background: Critical cut-off values of BMI-for-age z-scores (BAZ) are used to define “thinness”, “overweight” and “obesity”, but the validity of these cut-off values needs to be questioned in populations that are shorter or taller than the reference. We hypothesized that the prevalence of thinness, overweight, and obesity depends on population height and performed a random simulation. Methods: We created virtual child populations aged 2-10 years with normally distributed height expressed as height-for-age z-scores (HAZ) and weight expressed as weight-for-age z-score (WAZ), based on WHO growth standards and references, with a correlation r=0.7 between height and weight. We adjusted weight-for-height and calculated BAZ. Results: BAZ depends on height and age. In short children (mean HAZ=-2 to HAZ=-3), the prevalence of thinness falls to less than 1% in the youngest and rises up to 10% (mean HAZ=-2) and up to 13% (mean HAZ=-3) at age 10 years. The prevalence of obesity rises to up to 7% in the shortest and youngest and falls close to zero at age 10. Short young children and tall older children are more prone to be misclassified as overweight. Conclusions: The prevalence of thinness, overweight and obesity depends on height and age. The coexistence of being short and being overweight – currently referred to as “double burden of malnutrition” – needs consideration as to what extent this condition is a health issue or reflects calculation artefacts. The arithmetic dilemma particularly affects young children in short populations. We suggest abstaining from defining “thinness”, “overweight”, or “obesity” by BMI z-scores. Different states of under- and malnutrition should rather be classified by direct or indirect measures of body fat.
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- 2022
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17. Indonesian National Growth Reference Charts Better Reflect Height and Weight of Children in West Java, Indonesia, than WHO Child Growth Standards
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Novina Novina, Michael Hermanussen, Christiane Scheffler, Aman B. Pulungan, Yoyos Dias Ismiarto, Yudhie Andriyana, Vitriana Biben, and Budi Setiabudiawan
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anthropometric measurement ,indonesian national growth reference charts ,world health organization child growth standards ,bandung district children ,undernutrition ,Pediatrics ,RJ1-570 ,Diseases of the endocrine glands. Clinical endocrinology ,RC648-665 - Abstract
Objective:The Indonesia Basic Health Research 2018 indicates that Indonesian children are still among the shortest in the world. When referred to World Health Organization Child Growth Standards (WHOCGS), the prevalence of stunting reaches up to 43% in several Indonesian districts. Indonesian National Growth Reference Charts (INGRC) were established in order to better distinguish between healthy short children and children with growth disorders. We analyzed height and weight measurements of healthy Indonesian children using INGRC and WHOCGS.Methods:6972 boys and 5800 girls (n=12,772), aged 0-59 months old, from Bandung District were measured. Z-scores of length/height and body mass index were calculated based on INGRC and WHOCGS.Results:Under 5-year-old Indonesian children raised in Bandung are short and slim. Mean height z-scores of boys is -2.03 [standard deviation (SD) 1.31], mean height z-scores of girls is -2.03 (SD 1.31) when referred to WHOCGS indicating that over 50% of these children are stunted. Bandung children are heterogeneous, with substantial subpopulations of tall children. Depending on the growth reference used, between 9% and 15% of them are wasted. Wasted children are on average half a SD taller than their peers.Conclusion:WHOCGS seriously overestimates the true prevalence of undernutrition in Indonesian children. The present investigation fails to support evidence of undernutrition at a prevalence similar to the over 50% prevalence of stunting (WHOCGS) versus 13.3% (INGRC). We suggest refraining from using WHOCGS, and instead applying INGRC that closely mirror height and weight increments in Bandung children. INGRC appear superior for practical and clinical purposes, such as detecting growth and developmental disorders.
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- 2020
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18. Stunting does not impair physical fitness in Indonesian school children
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Christiane Scheffler and Michael Hermanussen
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stunting ,standing long jump ,handgrip strength ,SEPE ,frame index ,Medicine ,Biology (General) ,QH301-705.5 - Abstract
Background Physical fitness is decreased in malnourished children and adults. Poor appearance and muscular flaccidity are among the first signs of malnutrition. Malnutrition is often associated with stunting. Objectives We test the hypotheses that stunted children of low social strata are physically less fit than children of high social strata. Sample We investigated 354 school girls and 369 school boys aged 5.83 to 13.83 (mean 9.54) years from three different social strata in Kupang (West-Timor, Indonesia) in 2020. Methods We measured height, weight, and elbow breadth, calculated standard deviation (SDS) of height and weight according to CDC references, and the Frame index as an indicator of long-term physical fitness, and we tested physical fitness in standing long jump and hand grip strength. Results Children of low social strata are physically fittest. They jump longer distances, and they have higher values in the Frame index. No association exists between height SDS and physical fitness, neither in respect to standing long jump, nor to hand grip strength. Conclusion Stunting does not impair physical fitness in Indonesian school children. Our results support the concept that SEPE (social-economic-political-emotional) factors are involved in the regulation of human growth.
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- 2021
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19. Growth during times of fear and emotional stress
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Christiane Scheffler, Alan D. Rogol, Mirela Iancu, Tomasz Hanc, Annang Giri Moelyo, Andrej Suchomlinov, Lidia Lebedeva, Yehuda Limony, Martin Musalek, Gudrun Veldre, Elena Z. Godina, Sylvia Kirchengast, Rebekka Mumm, Detlef Groth, Janina Tutkuviene, Sonja Böker, Basak Koca Ozer, Barbara Navazo, Laure Spake, Slawomir Koziel, and Michael Hermanussen
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stunting ,birth weight ,fear ,emotional stress ,economy ,SEPE ,Medicine ,Biology (General) ,QH301-705.5 - Abstract
Twenty-one scientists met for this year’s virtual conference on Auxology held at the University Potsdam, Germany, to discuss child and adolescent growth during times of fear and emotional stress. Growth within the broad range of normal for age and sex is considered a sign of good general health whereas fear and emotional stress can lead to growth faltering. Stunting is a sign of social disadvantage and poor parental education. Adverse childhood experiences affect child development, particularly in families with low parental education and low socioeconomic status. Negative effects were also shown in Indian children exposed prenatally and in early postnatal life to the cyclone Aila in 2009. Distrust, fears and fake news regarding the current Corona pandemic received particular attention though the effects generally appeared weak. Mean birth weight was higher; rates of low, very and extremely low birth weight were lower. Other topics discussed by the participants, were the influences of economic crises on birth weight, the measurement of self-confidence and its impact on growth, the associations between obesity, peer relationship, and behavior among Turkish adolescents, height trends in Indonesia, physiological neonatal weight loss, methods for assessing biological maturation in sportsmen, and a new method for skeletal age determination. The participants also discussed the association between acute myocardial infarction and somatotype in Estonia, rural-urban growth differences in Mongolian children, socio-environmental conditions and sexual dimorphism, biological mortality bias, and new statistical techniques for describing inhomogeneity in the association of bivariate variables, and for detecting and visualizing extensive interactions among variables.
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- 2021
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20. Vietnamese migrants are as tall as they want to be
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Christiane Scheffler, Thi Hong Nguyen, and Michael Hermanussen
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body height ,regulation of growth ,migrants ,Social-Economic-Political-Emotional (SEPE) factors ,Medicine ,Biology (General) ,QH301-705.5 - Abstract
Background Members of the same social group tent to have the same body height. Migrants tend to adjust in height to their host communities. Objectives Social-Economic-Political-Emotional (SEPE) factors influence growth. We hypothesized that Vietnamese young adult migrants in Germany (1) are taller than their parents, (2) are as tall as their German peers, and (3) are as tall as predicted by height expectation at age 13 years. Sample and Methods The study was conducted in 30 male and 54 female Vietnamese migrants (mean age 26.23 years. SD=4.96) in Germany in 2020. Information on age, sex, body height, school and education, job, height and ethnicity of best friend, migration history and cultural identification, parental height and education, and recalled information on their personal height expectations at age 13 years were obtained by questionnaire. The data were analyzed by St. Nicolas House Analysis (SNHA) and multiple regression. Results Vietnamese young adults are taller than their parents (females 3.85cm, males 7.44cm), but do not fully attain height of their German peers. The body height is positively associated with the height of best friend (p < 0.001), the height expectation at age 13 year (p < 0.001), and father height (p=0.001). Conclusion Body height of Vietnamese migrants in Germany reflects competitive growth and strategic growth adjustments. The magnitude of this intergenerational trend supports the concept that human growth depends on Social-Economic-Political-Emotional (SEPE) factors.
- Published
- 2021
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- View/download PDF
21. Growth, Nutrition and Economy
- Author
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Michael Hermanussen, Christiane Scheffler, Lidia Martin, Detlef Groth, James G. Waxmonsky, James Swanson, Natalia Nowak-Szczepanska, Aleksandra Gomula, Anna Apanasewicz, Jan M. Konarski, Robert M. Malina, Sylwia Bartkowiak, Lidia Lebedeva, Andrej Suchomlinov, Vsevolod Konstantinov, Werner Blum, Yehuda Limony, Raja Chakraborty, Sylvia Kirchengast, Janina Tutkuviene, Egle Marija Jakimaviciene, Ramune Cepuliene, Daniel Franken, Bárbara Navazo, Annang G. Moelyo, Takashi Satake, and Slawomir Koziel
- Subjects
nutrition ,stunting ,socioeconomy ,education ,secular changes ,pubertal timing ,Medicine ,Biology (General) ,QH301-705.5 - Abstract
Twenty-three scientists met at Krobielowice, Poland to discuss the role of growth, nutrition and economy on body size. Contrasting prevailing concepts, re-analyses of studies in Indonesian and Guatemalan school children with high prevalence of stunting failed to provide evidence for an association between nutritional status and body height. Direct effects of parental education on growth that were not transmitted via nutrition were shown in Indian datasets using network analysis and novel statistical methods (St. Nicolas House Analysis) that translate correlation matrices into network graphs. Data on Polish children suggest significant impact of socioeconomic sensitivity on child growth, with no effect of maternal money satisfaction. Height and maturation tempo affect the position of a child among its peers. Correlations also exist between mood disorders and height. Secular changes in height and weight varied across decades independent of population size. Historic and recent Russian data showed that height of persons whose fathers performed manual work were on average four cm shorter than persons whose fathers were high-degree specialists. Body height, menarcheal age, and body proportions are sensitive to socioeconomic variables. Additional topics included delayed motherhood and its associations with newborn size; geographic and socioeconomic indicators related to low birth weight, prematurity and stillbirth rate; data on anthropometric history of Brazil, 1850-1950; the impact of central nervous system stimulants on the growth of children with attention-deficit/hyperactivity disorder; and pituitary development and growth hormone secretion. Final discussions debated on reverse causality interfering between social position, and adolescent growth and developmental tempo.
- Published
- 2021
- Full Text
- View/download PDF
22. Westernization of self-perception in modern affluent Indonesian school children
- Author
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Sonja Boeker, Michael Hermanussen, and Christiane Scheffler
- Subjects
self-perception ,social status ,westernization ,cultural dependence ,Medicine ,Biology (General) ,QH301-705.5 - Abstract
Background Subjective Social Status is used as an important predictor for psychological and physiological findings, most commonly measured with the MacArthur Scale (Ladder Test). Previous studies have shown that this test fits better in Western cultures. The idea of a social ladder itself and ranking oneself “higher” or “lower” is a concept that accords to the Western thinking. Objectives We hypothesize that in a culture where only the elites have adapted to a Western lifestyle, the test results reflect a higher level of accuracy for this stratum. We also expect that self-perception differs per sex. Sample and Methods We implemented the Ladder Test in a study of Indonesian schoolchildren aged between 5 and 13 years (boys N = 369, girls N= 364) from non-private and private schools in Kupang in 2020. Results Our analysis showed that the Ladder Test results were according to the Western expectations only for the private school, as the Ladder Scores significantly decreased with age (LM: p = 0.04). The Ladder Test results are best explained by “Education Father” for the non-private school pupils (p = 0.01) and all boys (p = 0.04), by “School Grades” for the private school cohort (p = 0.06) and by “Household Score” for girls (p =0.09). Conclusion This finding indicates that the concept of ranking oneself “high” or “low” on a social ladder is strongly implicated with Western ideas. A ladder implies social movement by “climbing” up or down. According to that, reflection of self-perception is influenced by culture.
- Published
- 2021
- Full Text
- View/download PDF
23. Estimation of percentage of body fat in field studies – a method based on relative elbow breadth (Frame Index) and BMI
- Author
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Rebekka Mumm, Anna Reimann, and Christiane Scheffler
- Subjects
body fat estimator ,body composition ,skeletal robusticity ,hidden obesity ,normal weigh obese ,Medicine ,Biology (General) ,QH301-705.5 - Abstract
Background Over the last 20 years, a decreasing trend in external skeletal robusticity and an increasing trend in overweight and obesity was observed worldwide in adults and children as modern lifestyles in nutritional and activity behavior have changed. However, body mass index (BMI) as a measure for overweight is not an ideal predictor of % body fat (%BF) either in children and adolescents or in adults. On the contrary, it disguises a phenomenon called “hidden obesity”. Objectives We aim to approximate %BF by combining skeletal robusticity and BMI and develop an estimation-based tool to identify normal weight obese children and adolescents. Sample and Methods We analyzed cross-sectional data on height, weight, elbow breadth, and skinfold thickness (triceps and subscapular) of German children aged 6 to 18 years (N=15,034). We used modified Hattori charts and multiple linear regression to develop a tool, the “%BF estimator”, to estimate %BF by using BMI and skeletal robusticity measured as Frame Index. Results Independent of sex and age an increase in BMI is associated with an increase in %BF, an increase in Frame Index is associated with a decrease in %BF. The developed tool “%BF estimator” allows the estimation of %BF per sex and age group after calculation of BMI and Frame Index. Conclusion The “%BF estimator” is an easily applicable tool for the estimation of %BF in respect of body composition for clinical practice, screening, and public health research. It is non-invasive and has high accuracy. Further, it allows the identification of normal weight obese children and adolescents.
- Published
- 2021
- Full Text
- View/download PDF
24. Decreased external skeletal robustness in schoolchildren--a global trend? Ten year comparison of Russian and German data.
- Author
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Katrin Rietsch, Elena Godina, and Christiane Scheffler
- Subjects
Medicine ,Science - Abstract
OBJECTIVES: Obesity and a reduced physical activity are global developments. Physical activity affects the external skeletal robustness which decreased in German children. It was assumed that the negative trend of decreased external skeletal robustness can be found in other countries. Therefore anthropometric data of Russian and German children from the years 2000 and 2010 were compared. METHODS: Russian (2000/2010 n = 1023/268) and German (2000/2010 n = 2103/1750) children aged 6-10 years were investigated. Height, BMI and external skeletal robustness (Frame-Index) were examined and compared for the years and the countries. Statistical analysis was performed by Mann-Whitney-Test. RESULTS: Comparison 2010 and 2000: In Russian children BMI was significantly higher; boys were significantly taller and exhibited a decreased Frame-Index (p = .002) in 2010. German boys showed significantly higher BMI in 2010. In both sexes Frame-Index (p = .001) was reduced in 2010. Comparison Russian and German children in 2000: BMI, height and Frame-Index were different between Russian and German children. German children were significantly taller but exhibited a lower Frame-Index (p
- Published
- 2013
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- View/download PDF
25. Working against forgetting – Infants’ feeding and weight gain at the time of Juhan Aul
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Michael Hermanussen and Christiane Scheffler
- Subjects
General Engineering - Abstract
A hundred and twenty-five years ago, European infants grew differently from modern infants. We show weight gains of 20 healthy children weighed longitudinally from birth to age 1 year published by Camerer in 1882. The data illustrate the prevalent historic concepts of infant nutrition practiced by German civil servants, lawyers, merchants, university professors, physicians, foresters and farmers. Breastfeeding by the mother was not truly appreciated in those days; children were often breastfed by wet nurses or received bottled milk of various composition. Bottle feeding mainly consisted of diluted cow’s milk with some added carbohydrates without evidence that appropriate amounts of oil, butter or other fatty components had been added. French children from 1914 showed similar weight gain patterns suggesting similar feeding practices. The historical data suggest that energy deficient infant formula had regularly been fed in the late 19th and the early 20th century Europe regardless of wealth and social class. The data question current concerns that temporarily feeding energy deficient infant formula may warrant serious anxieties regarding long-term cognitive, social and emotional behavioral development.
- Published
- 2022
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- View/download PDF
26. The socio‐endocrine regulation of human growth
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Michael Hermanussen, Sergei Erofeev, and Christiane Scheffler
- Subjects
Neurons ,Child Development ,Human Growth Hormone ,Pediatrics, Perinatology and Child Health ,Humans ,General Medicine ,Insulin-Like Growth Factor I ,Child ,Social Behavior ,Body Height - Abstract
Growth is a multifarious phenomenon that has been studied by nutritionists, economists, paediatric endocrinologists; archaeologists, child psychologists and other experts. Yet, a unifying theory of understanding growth regulation is still lacking.Critical review of the literature.We summarise evidence linking social competition and its effect on hierarchies in social structures, with the neuronal networks of the ventromedial hypothalamus and body size. The endocrine signalling system regulating growth hormone, Insulin-like-Growth-Factor1 and skeletal growth, is well conserved in the evolution of vertebrata for some 400 million years. The link between size and status permits adaptive plasticity, competitive growth and strategic growth adjustments also in humans. Humans perceive size as a signal of dominance with tallness being favoured and particularly prevalent in the upper social classes.Westernised societies are competitive. People are tall, and "open to change." Social values include striving for status and prestige implying socio-economic domination. We consider the transition of political and social values following revolutions and civil wars, as key elements that interact with the evolutionarily conserved neuroendocrine competence for adaptive developmental plasticity, overstimulate the hypothalamic growth regulation and finally lead to the recent historic increases in average height.
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- 2022
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27. Evidence of chronic undernutrition in late 19th century German infants of all social classes
- Author
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Michael Hermanussen and Christiane Scheffler
- Subjects
ddc:570 ,ddc:610 ,Institut für Biochemie und Biologie ,Extern - Abstract
125 years ago, European infants grew differently from modern infants. We show weight gains of 20 healthy children weighed longitudinally from birth to age 1 year, published by Camerer in 1882. The data illustrate the historically prevalent concepts of infant nutrition practiced by German civil servants, lawyers, merchants, university professors, physicians, foresters and farmers. Breastfeeding by the mother was not truly appreciated in those days; children were often breastfed by wet nurses or received bottled milk. Bottle feeding mainly used diluted cow’s milk with some added carbohydrates, without evidence that appropriate amounts of oil, butter or other fatty components were added. French children from 1914 showed similar weight gain patterns suggesting similar feeding practices. The historical data suggest that energy deficient infant formula was fed regularly in the late 19th and early 20th century Europe, regardless of wealth and social class. The data question current concerns that temporarily feeding energy deficient infant formula may warrant serious anxieties regarding long-term cognitive, social and emotional behavioral development.
- Published
- 2022
28. Human growth data analyses and statistics
- Author
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Michael Hermanussen, Detlef Groth, and Christiane Scheffler
- Abstract
Students learn by repetition. Repetition is essential, but repetition needs questioning, and questioning the repertoire belongs to the essential tasks of student education. Guiding students to questioning was and is our prime motive to offer our International Student Summer Schools. The data were critically discussed among the students, in the twilight of Just So Stories, common knowledge, and prompted questioning of contemporary solutions. For these schools, the students bring their own data, carry their preliminary concepts, and in group discussions, they may have to challenge these concepts. Catch-up growth is known to affect long bone growth, but different opinions exist to what extent it also affects body proportions. Skeletal age and dental development are considered appropriate measures of maturation, but it appears that both system develop independently and are regulated by different mechanisms. Body weight distributions are assumed to be skewed, yet, historic data disproved this assumption. Many discussions focused on current ideas of global growth standards as a common yardstick for all populations world-wide, with new statistical tools being developed including network reconstruction and evaluation of the reconstructs to determine the confidence of graph prediction methods.
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- 2022
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29. Dental age is an independent marker of biological age
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Sonja Boeker, Michael Hermanussen, and Christiane Scheffler
- Subjects
ddc:570 ,ddc:610 ,Institut für Biochemie und Biologie ,Extern - Abstract
Background: Biological age markers are a crucial indicator whether children are decelerated in growth tempo. Skeletal maturation is the standard measure. Yet, it relies on exposing children to x-radiation. Dental eruption is a potential, but highly debated, radiation free alternative. Objectives: We assess the interrelationship between dental eruption and other maturational markers. We hypothesize that dental age correlates with body height and skeletal age. We further evaluate how the three different variables behave in cohorts from differing social backgrounds. Sample and Method: Dental, skeletal and height data from the 1970s to 1990s from Guatemalan boys were converted into standard deviation scores, using external references for each measurement. The boys, aged between 7 and 12, derived from different social backgrounds (middle SES (N = 6529), low-middle SES (N = 736), low SES Ladino (N = 3653) and low SES Maya (N = 4587). Results: Dental age shows only a weak correlation with skeletal age (0.18) and height (0.2). The distinction between cohorts differs according to each of the three measurements. All cohorts differ significantly in height. In skeletal maturation, the middle SES cohort is significantly advanced compared to all other cohorts. The periodically malnourished cohorts of low SES Mayas and Ladinos are significantly delayed in dental maturation compared to the well-nourished low-middle and middle class Ladino children. Conclusion: Dental development is an independent system, that is regulated by different mechanisms than skeletal development and growth. Tooth eruption is sensitive to nutritional status, whereas skeletal age is more sensitive to socioeconomic background.
- Published
- 2022
30. Decrease of external skeletal robustness (Frame Index) between two cohorts of school children living in Puerto Madryn, Argentina at the beginning of the 21st century
- Author
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Evelia Edith Oyhenart, Christiane Scheffler, Rebekka Mumm, Bárbara Navazo, and Silvia Lucrecia Dahinten
- Subjects
Male ,Elbow breadth ,Index (economics) ,Adolescent ,elbow breadth ,Argentina ,SCHOOL CHILDREN ,skeletal robustness ,Russia ,purl.org/becyt/ford/3.3 [https] ,HEIGHT ,Robustness (computer science) ,Germany ,Humans ,Child ,Ecology, Evolution, Behavior and Systematics ,Czech Republic ,Antropología ,ARGENTINA ,ELBOW BREADTH ,school children ,Frame (networking) ,General Medicine ,Cross-Sectional Studies ,Geography ,Anthropology ,Female ,purl.org/becyt/ford/3 [https] ,Animal Science and Zoology ,Poland ,SKELETAL ROBUSTNESS ,Humanities ,height - Abstract
Background: It has been shown that modern life style with reduced physical activity can lead to lower bone accumulation. Also a decline trend in external skeletal robustness in children and young adolescents, measured by the Frame Index (FI), seems to have a parallel trend with the increase in overweight and obesity. Based on these findings we estimate that likely, the FI should be changed after a decade in the Argentinean population as well as in others population of the world. Thereby, the aim of the present study was to describe, using the FI, the pattern of external skeletal robustness in school children aged 6–14 years from two cohorts of Argentina (Puerto Madryn, Chubut) and to compare them with the European reference (Czech Republic, Germany, Poland and Russia). Methods: Elbow breadth and height of Puerto Madryn school children were collected in two cross-sectional studies conducted between 2001–2006 (cohort 1 = C1) and 2014– 2016 (cohort 2 = C2). Percentiles (P) values, for males and females, from C1 and C2 were calculated combining the LMS- method and its extension. A t-test has been used to compare, by age and sex, the FI values between the Argentinean cohorts and the European reference (ER). Then, in order to know the percentage of the variation of the percentiles values between cohorts, as well as with ER, percent differences between means (PDM%) were employed. Results: FI from Argentinean cohorts differed significantly from ER. Even more, C2 was not only smaller than ER, but also than C1. In males, C1-C2 showed significant differences at 6–8, 11 and 12 years and in females at all ages. Then, respect to ER each Argentinean cohort showed significant differences in males of C1 at 6, 12–14 years and in females at 6 and 11–14 years; and of C2, in both sexes, from 6 to 14 years. The PDM% values for elbow breadth of male were negative in ER-C1 in all percentiles analyzed; in ER-C2 positive (P3 and P50) and negative (P97) and C1-C2 recorded positive values. In females, elbow breadth showed negative values for ER-C1 (P50 and P97), and positive for the remaining values. Finally, height registered, in both sexes, negative values in ER-C1 (except P97 in females), ER-C2 and C1-C2. Conclusions: After ten years of the first study carried on in Puerto Madryn, school children show a negative trend in the external skeletal robustness. Additionally, the children of both Argentinean cohorts have lower values compared to the European reference, and mainly the actual cohort. This situation would be explained, in part, by the progressive increase over time of overweight and obesity as consequence, among others, of the change in the quantity and/or quality of the food that children have access to and with the physical activity they do at school and outside., Laboratorio de Investigaciones en Ontogenia y Adaptación “Dra. Evelia E. Oyhenart”
- Published
- 2020
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31. Indonesian National Growth Reference Charts Better Reflect Height and Weight of Children in West Java, Indonesia, than WHO Child Growth Standards
- Author
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Christiane Scheffler, Yoyos Dias Ismiarto, Michael Hermanussen, Novina Novina, Vitriana Biben, Budi Setiabudiawan, Aman B Pulungan, and Yudhie Andriyana
- Subjects
Male ,Endocrinology, Diabetes and Metabolism ,Anthropometric measurement ,030209 endocrinology & metabolism ,West java ,lcsh:Diseases of the endocrine glands. Clinical endocrinology ,World health ,Body Mass Index ,03 medical and health sciences ,0302 clinical medicine ,Endocrinology ,Reference Values ,Indonesian National Growth Reference Charts ,medicine ,Humans ,030212 general & internal medicine ,Growth Charts ,Child growth ,Growth Disorders ,Bandung District children ,lcsh:RC648-665 ,business.industry ,Body Weight ,lcsh:RJ1-570 ,Infant, Newborn ,Infant ,lcsh:Pediatrics ,Anthropometry ,Prognosis ,medicine.disease ,Body Height ,language.human_language ,World Health Organization Child Growth Standards ,undernutrition ,Indonesian ,Malnutrition ,Cross-Sectional Studies ,Indonesia ,Child, Preschool ,Pediatrics, Perinatology and Child Health ,language ,Female ,Original Article ,business ,Body mass index ,Follow-Up Studies ,Demography - Abstract
Objective The Indonesia Basic Health Research 2018 indicates that Indonesian children are still among the shortest in the world. When referred to World Health Organization Child Growth Standards (WHOCGS), the prevalence of stunting reaches up to 43% in several Indonesian districts. Indonesian National Growth Reference Charts (INGRC) were established in order to better distinguish between healthy short children and children with growth disorders. We analyzed height and weight measurements of healthy Indonesian children using INGRC and WHOCGS. Methods 6972 boys and 5800 girls (n=12,772), aged 0-59 months old, from Bandung District were measured. Z-scores of length/height and body mass index were calculated based on INGRC and WHOCGS. Results Under 5-year-old Indonesian children raised in Bandung are short and slim. Mean height z-scores of boys is -2.03 [standard deviation (SD) 1.31], mean height z-scores of girls is -2.03 (SD 1.31) when referred to WHOCGS indicating that over 50% of these children are stunted. Bandung children are heterogeneous, with substantial subpopulations of tall children. Depending on the growth reference used, between 9% and 15% of them are wasted. Wasted children are on average half a SD taller than their peers. Conclusion WHOCGS seriously overestimates the true prevalence of undernutrition in Indonesian children. The present investigation fails to support evidence of undernutrition at a prevalence similar to the over 50% prevalence of stunting (WHOCGS) versus 13.3% (INGRC). We suggest refraining from using WHOCGS, and instead applying INGRC that closely mirror height and weight increments in Bandung children. INGRC appear superior for practical and clinical purposes, such as detecting growth and developmental disorders.
- Published
- 2020
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32. Catch-up growth is a better indicator of undernutrition than thresholds for stunting
- Author
-
Michael Hermanussen, Christiane Scheffler, and Barry Bogin
- Subjects
Male ,Body height ,Medicine (miscellaneous) ,Catch-up growth ,Nutritional Status ,030209 endocrinology & metabolism ,03 medical and health sciences ,0302 clinical medicine ,Statistical significance ,Medicine ,Humans ,030212 general & internal medicine ,Child ,Growth Disorders ,Nutritional Status and Body Composition ,Nutrition and Dietetics ,Anthropometry ,business.industry ,Malnutrition ,Public Health, Environmental and Occupational Health ,Reproducibility of Results ,Growth spurt ,Circumference ,medicine.disease ,Guatemala ,Social-economic-political-emotional (SEPE) factors ,Skinfold thickness ,Cross-Sectional Studies ,Indonesia ,Female ,business ,No threshold for stunting ,Demography ,Research Paper - Abstract
Objective:Stunting (height-for-age < −2 sd) is one of the forms of undernutrition and is frequent among children of low- and middle-income countries. But stunting perse is not a synonym of undernutrition. We investigated association between body height and indicators of energetic undernutrition at three critical thresholds for thinness used in public health: (1) BMI SDS < −2; (2) mid-upper arm circumference divided by height (MUAC (mm) × 10/height (cm) < 1·36) and (3) mean skinfold thickness (SF) < 7 mm and to question the reliability of thresholds as indicators of undernutrition.Design:Cross-sectional study; breakpoint analysis.Setting:Rural and urban regions of Indonesia and Guatemala – different socio-economic status (SES).Participants:1716 Indonesian children (6·0–13·2 years) and 3838 Guatemalan children (4·0–18·9 years) with up to 50 % stunted children.Results:When separating the regression of BMI, MUAC or SF, on height into distinguishable segments (breakpoint analysis), we failed to detect relevant associations between height, and BMI, MUAC or SF, even in the thinnest and shortest children. For BMI and SF, the breakpoint analysis either failed to reach statistical significance or distinguished at breakpoints above critical thresholds. For MUAC, the breakpoint analysis yielded negative associations between MUAC/h and height in thin individuals. Only in high SES Guatemalan children, SF and height appeared mildly associated with R2 = 0·017.Conclusions:Currently used lower thresholds of height-for-age (stunting) do not show relevant associations with anthropometric indicators of energetic undernutrition. We recommend using the catch-up growth spurt during early re-feeding instead as immediate and sensitive indicator of past undernourishment. We discuss the primacy of education and social-economic-political-emotional circumstances as responsible factors for stunting.
- Published
- 2020
33. Reply to the letter titled 'Pathologizing normal height or identifying chronic malnutrition: Public health concerns of calling stunting normal' by Faizi, Zubair and Tasleem (2022)
- Author
-
Christiane Scheffler and Michael Hermanussen
- Subjects
Anthropology ,Malnutrition ,Genetics ,Humans ,Public Health ,Anatomy ,Growth Disorders ,Ecology, Evolution, Behavior and Systematics - Published
- 2022
- Full Text
- View/download PDF
34. Secular trends in gestational weight gain and parity on birth weight: An editorial
- Author
-
Christiane Scheffler and Michael Hermanussen
- Subjects
business.industry ,Birth weight ,Gestational Age ,General Medicine ,Gestational Weight Gain ,Body Mass Index ,Secular variation ,Parity ,Pregnancy ,Pediatrics, Perinatology and Child Health ,Birth Weight ,Humans ,Medicine ,Gestation ,Female ,medicine.symptom ,business ,Parity (mathematics) ,Weight gain ,Demography - Published
- 2020
- Full Text
- View/download PDF
35. Statistical Approaches to Developmental and Growth Data of Children and Adolescents – an editorial to student research conducted during the 3rd International Student Summer School, July 2019, Potsdam and Gülpe, Germany
- Author
-
Michael Hermanussen, Detlef Groth, and Christiane Scheffler
- Subjects
Medical education ,Parental education ,Anthropology ,Growth data ,Animal Science and Zoology ,General Medicine ,Psychology ,Student research ,Socioeconomic status ,Ecology, Evolution, Behavior and Systematics - Published
- 2020
- Full Text
- View/download PDF
36. Westernization of self-perception in modern affluent Indonesian school children
- Author
-
Michael Hermanussen, Christiane Scheffler, and Sonja Boeker
- Subjects
Indonesian ,Scale (social sciences) ,education ,Cohort ,language ,Psychology ,Self perception ,language.human_language ,Westernization ,Social status ,Developmental psychology ,Test (assessment) ,Social movement - Abstract
Background Subjective Social Status is used as an important predictor for psychological and physiological findings, most commonly measured with the MacArthur Scale (Ladder Test). Previous studies have shown that this test fits better in Western cultures. The idea of a social ladder itself and ranking oneself “higher” or “lower” is a concept that accords to the Western thinking. Objectives We hypothesize that in a culture where only the elites have adapted to a Western lifestyle, the test results reflect a higher level of accuracy for this stratum. We also expect that self-perception differs per sex. Sample and Methods We implemented the Ladder Test in a study of Indonesian schoolchildren aged between 5 and 13 years (boys N = 369, girls N= 364) from non-private and private schools in Kupang in 2020. Results Our analysis showed that the Ladder Test results were according to the Western expectations only for the private school, as the Ladder Scores significantly decreased with age (LM: p = 0.04). The Ladder Test results are best explained by “Education Father” for the non-private school pupils (p = 0.01) and all boys (p = 0.04), by “School Grades” for the private school cohort (p = 0.06) and by “Household Score” for girls (p =0.09). Conclusion This finding indicates that the concept of ranking oneself “high” or “low” on a social ladder is strongly implicated with Western ideas. A ladder implies social movement by “climbing” up or down. According to that, reflection of self-perception is influenced by culture.
- Published
- 2021
- Full Text
- View/download PDF
37. Growth, Nutrition and Economy : Proceedings of the 27th Aschauer Soiree, held at Krobielowice, Poland, November 16th 2019
- Author
-
Andrej Suchomlinov, Sylvia Kirchengast, Raja Chakraborty, Sylwia Bartkowiak, Slawomir Koziel, Robert M. Malina, Lidia Lebedeva, Takashi Satake, Egle Marija Jakimaviciene, Daniel Franken, Christiane Scheffler, Michael Hermanussen, Detlef Groth, Aleksandra Gomula, Jan M. Konarski, James M. Swanson, Ramune Cepuliene, Yehuda Limony, Lidia Martin, Werner F. Blum, Natalia Nowak-Szczepanska, Bárbara Navazo, Vsevolod Konstantinov, Janina Tutkuviene, Anna Apanasewicz, Annang G. Moelyo, and James G. Waxmonsky
- Subjects
education ,Body proportions ,socioeconomy ,secular changes ,pubertal timing ,stunting ,Anthropometry ,Affect (psychology) ,medicine.disease ,Growth hormone secretion ,Low birth weight ,nutrition ,Economy ,Mood disorders ,medicine ,Social position ,Nutrition ,Stunting ,Socioeconomy ,Education ,Secular changes ,Pubertal timing ,Ciencias Naturales ,medicine.symptom ,Psychology ,Socioeconomic status - Abstract
Twenty-three scientists met at Krobielowice, Poland to discuss the role of growth, nutrition and economy on body size. Contrasting prevailing concepts, re-analyses of studies in Indonesian and Guatemalan school children with high prevalence of stunting failed to provide evidence for an association between nutritional status and body height. Direct effects of parental education on growth that were not transmitted via nutrition were shown in Indian datasets using network analysis and novel statistical methods (St. Nicolas House Analysis) that translate correlation matrices into network graphs. Data on Polish children suggest significant impact of socioeconomic sensitivity on child growth, with no effect of maternal money satisfaction. Height and maturation tempo affect the position of a child among its peers. Correlations also exist between mood disorders and height. Secular changes in height and weight varied across decades independent of population size. Historic and recent Russian data showed that height of persons whose fathers performed manual work were on average four cm shorter than persons whose fathers were high-degree specialists. Body height, menarcheal age, and body proportions are sensitive to socioeconomic variables. Additional topics included delayed motherhood and its associations with newborn size; geographic and socioeconomic indicators related to low birth weight, prematurity and stillbirth rate; data on anthropometric history of Brazil, 1850-1950; the impact of central nervous system stimulants on the growth of children with attention-deficit/hyperactivity disorder; and pituitary development and growth hormone secretion. Final discussions debated on reverse causality interfering between social position, and adolescent growth and developmental tempo., Facultad de Ciencias Naturales y Museo
- Published
- 2021
38. Estimation of percentage of body fat in field studies – a method based on relative elbow breadth (Frame Index) and BMI
- Author
-
Christiane Scheffler, Anna Reimann, and Rebekka Mumm
- Subjects
Elbow breadth ,Estimation ,Index (economics) ,business.industry ,Overweight ,medicine.disease ,Obesity ,Normal weight ,Linear regression ,medicine ,medicine.symptom ,business ,Body mass index ,Demography - Abstract
Background Over the last 20 years, a decreasing trend in external skeletal robusticity and an increasing trend in overweight and obesity was observed worldwide in adults and children as modern lifestyles in nutritional and activity behavior have changed. However, body mass index (BMI) as a measure for overweight is not an ideal predictor of % body fat (%BF) either in children and adolescents or in adults. On the contrary, it disguises a phenomenon called “hidden obesity”. Objectives We aim to approximate %BF by combining skeletal robusticity and BMI and develop an estimation-based tool to identify normal weight obese children and adolescents. Sample and Methods We analyzed cross-sectional data on height, weight, elbow breadth, and skinfold thickness (triceps and subscapular) of German children aged 6 to 18 years (N=15,034). We used modified Hattori charts and multiple linear regression to develop a tool, the “%BF estimator”, to estimate %BF by using BMI and skeletal robusticity measured as Frame Index. Results Independent of sex and age an increase in BMI is associated with an increase in %BF, an increase in Frame Index is associated with a decrease in %BF. The developed tool “%BF estimator” allows the estimation of %BF per sex and age group after calculation of BMI and Frame Index. Conclusion The “%BF estimator” is an easily applicable tool for the estimation of %BF in respect of body composition for clinical practice, screening, and public health research. It is non-invasive and has high accuracy. Further, it allows the identification of normal weight obese children and adolescents.
- Published
- 2021
- Full Text
- View/download PDF
39. The network effects on conscripts’ height in the central provinces of Russian empire in the middle of XIX century – at the beginning of XX century
- Author
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Lidia Lebedeva, Michael Hermanussen, Elena Godina, Detlef Groth, and Christiane Scheffler
- Subjects
Male ,Body height ,media_common.quotation_subject ,Empire ,History, 19th Century ,Context (language use) ,General Medicine ,History, 20th Century ,Body Height ,Russia ,Military Personnel ,Geography ,Anthropology ,Serfdom ,Humans ,Animal Science and Zoology ,Poland ,Physical geography ,Ecology, Evolution, Behavior and Systematics ,media_common ,Transport infrastructure - Abstract
Background: We investigated average body height in the central provinces of the Russian empire in the middle of XIX century in view of the concept of "community effects on height". We analyzed body height correlations between neighboring districts at this time. We added information about secular changes in body height during the 19th century of this territory. Material and methods: The study used height data of conscripts, which were born in the years 1853-1863, and age 21 at the time of measurement. The territory of seven provinces was considered as a network with 105 nodes, each node representing one district with information on average male body height. In order to define neighboring districts three different approaches were used: based on the "common borders" method, based on Euclidean distances (from 60 to 120 km), based on real road connections. Results: Small but significant correlation coefficients were observed between 1st order districts in the network based on Euclidean distance of 100 km (r = 0.256, p-value = 0.006) and based on "the common borders" approach (r = 0.25, p-value = 0.02). Wherein no significant correlations were observed in the network based on road connections and between second order neighbors regardless of the method. Conclusion: Height correlation coefficients between 1st order neighboring districts observed in the Russian districts were very similar to values observed in the Polish study (r = 0.24). The considered Russian territory and the territory of Poland have a lot in common. They consist of both plains without mountains. In contradistinction to Poland the transport infrastructure in Russia was weakly developed in the middle of XIX century. In addition, the mobility of people was limited by serfdom. In this context the absent of significant correlation of second order neighbors can be explained by low population density and lack of migration and communication between the districts.
- Published
- 2019
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40. Body height in stunted Indonesian children depends directly on parental education and not via a nutrition mediated pathway – Evidence from tracing association chains by St. Nicolas House Analysis
- Author
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Michael Hermanussen, Christiane Scheffler, and Detlef Groth
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Male ,Parents ,Nutritional Status ,010501 environmental sciences ,Tracing ,01 natural sciences ,Standard deviation ,Correlation ,03 medical and health sciences ,0302 clinical medicine ,Statistics ,Humans ,030212 general & internal medicine ,Child ,Ecology, Evolution, Behavior and Systematics ,Partial correlation ,0105 earth and related environmental sciences ,Mathematics ,Anthropometry ,General Medicine ,Circumference ,Body Height ,language.human_language ,Indonesian ,Ranking ,Indonesia ,Anthropology ,language ,Educational Status ,Female ,Animal Science and Zoology - Abstract
Background: Multiple linear correlations between parameters can be shown in correlation matrices. Correlations can be ranked, but can also be visualized in network graphs. Yet, translating a correlation matrix into a network graph is not trivial. In view of a popular child game, we propose to name this method St. Nicolas House Analysis. Material and methods: We present a new method (St. Nicolas House Analysis) that helps translating correlation matrices into network graphs. The performance of this and other network reconstruction methods was tested in randomly created virtual scale-free networks, networks consisting of bands or hubs, using balanced classification rate and the F1-Score for correctly predicting existing and non-existing edges. Thereafter we analyzed anthropometric data and information on parental education, obtained from an anthropometric survey in 908 Indonesian boys and 808 Indonesian girls. Seven parameters were analyzed: child height standard deviation score (hSDS), child BMI standard deviation scores (BMI_SDS), mid-upper-arm circumference (MUAC), mean thickness of subscapular and triceps skinfold (mean SF), and elbow breadth; as well as maternal and paternal education (years of schooling). The parameters were considered as the nodes of the network; the edges represent the correlations between the nodes. Results: Performance measures, balanced classification rate and the F1-score, showed that St. Nicolas' House Analysis was superior to methods using sophisticated correlation value thresholds and methods based on partial correlations for analyzing bands and hubs. We applied this method also in an Indonesia data set. Ranking correlations showed the direct association between parental education and child growth. Conclusion: St. Nicolas House Analysis confirmed that growth of Indonesian school children directly depends on maternal education, with no evidence that this effect is mediated by the state of nutrition.
- Published
- 2019
- Full Text
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41. Genetik der Körperhöhe
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Barry Bogin, Michael Hermanussen, and Christiane Scheffler
- Subjects
Political science ,General Medicine ,Humanities - Abstract
Zusammenfassung Hintergrund Noch immer gründen heutige Analysen genetischer Zwillings- und Familienstudien auf mathematischen Ansätzen des frühen 20. Jahrhunderts, namentlich von Galton, Pearson und Fisher, und führen zu konventionellen Schätzwerten für die Heritabilität der Körperhöhe zwischen h² = 0,87 und h² = 0,93 bei Männern und zwischen h² = 0,68 und h² = 0,84 bei Frauen. Diese Werte sind wesentlich höher als moderne Schätzungen auf der Basis genomweiter Assoziationsstudien (GWAS), mit denen sich zwischen 12,3 % und 49 % der Körperhöhenvarianz im Erwachsenenalter erklären lassen. Diese so genannte „missing heritability“ gibt Anlass zu Missverständnissen. Diskussion Wir nehmen eine biokulturelle Perspektive ein, um Entwicklungsmerkmale zu verstehen, die nur auf den ersten Blick erblich erscheinen. Innerhalb sozialer Gruppen dient Körpergröße als Signal. Kompetitive Wachstumsstrategien (competitive growth strategies) und strategische Wachstumsanpassungen (strategic growth adjustments) insbesondere im Hinblick auf die Gefahr, aus einer führenden sozialen Rolle verdrängt zu werden (threat of being displaced) sind bei sozialen Säugern beschrieben und spielen sehr wahrscheinlich auch in menschlichen Sozialstrukturen eine wesentliche Rolle. Die Körperhöhe eines Menschen hängt von der Körperhöhe anderer Mitglieder seiner Peer Group ab. Im vergangenen Jahrhundert wurden Körperhöhentrends von bis zu 20 cm in manchen Populationen beobachtet (säkulare Trends). Dies ist Ausdruck von phänotypischer Plastizität und war Galton, Pearson und Fisher unbekannt. Schlussfolgerung Die beschriebene „missing heritability“ für Körperhöhe spiegelt die Diskrepanz zwischen moderner Wissenschaft und überholten Vermengungen von deterministischen und politischen Ideen des frühen 20. Jahrhunderts wider.
- Published
- 2019
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42. Body height as a social signal
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Christiane Scheffler and Michael Hermanussen
- Subjects
Geography ,Body height ,Acoustics ,Signal - Abstract
Body height has a signaling function among social mammals. Humans also perceive physical size as a signal and tend to associate stature and status. Taller men are perceived as more competent and authoritative. Studies in wild Kalahari male meerkats (Suricata suricatta) suggest that dominance itself can be a stimulus for growth allowing for competitive growth and strategic growth adjustments. Assuming that similar mechanisms on the control of growth are also relevant for humans, our understanding of the shortness of many Third World populations has to be revised. Short stature may no longer be exclusively understood as an expression of poverty, chronic malnutrition and poor health but as an expression of persistent feelings of inferiority and patronization in the face of the global spread and dominance of Western life and moral codes.
- Published
- 2019
- Full Text
- View/download PDF
43. Größenwahn : Zur Evolution biologischer Signale im sozialen Miteinander: ein Tuch aus 36 Fäden
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Michael Hermanussen, Christiane Scheffler, Michael Hermanussen, and Christiane Scheffler
- Subjects
- Zoology, Anthropology
- Abstract
Großsein ist großartig. Körpergröße ist ungeheuer wichtig. Wer groß ist, erscheint kompetent, verdient mehr Geld, nimmt bevorzugte Positionen in der Gesellschaft ein. Wer auf andere herabschauen kann, wirkt nicht nur auf seine Mitmenschen dominant, sondern ist zu allem Überfluss auch noch selbst von der eigenen Großartigkeit überzeugt. Diese und ähnliche Vorurteile bestehen nicht von ungefähr: sie haben evolutionsbiologische Hintergründe. Körpergröße ist ein Signal. Seine Regulation ist in der Wirbeltierreihe seit mindestens 400 Millionen Jahren konserviert – und weil dieses Signal auch von Menschen ganz selbstverständlich und strategisch genutzt wird, entzieht es sich fast vollständig unserer bewussten Wahrnehmung. Zwei international renommierte Wissenschaftler, ein Pädiater und eine Humanbiologin, zeigen erstmals in allgemeinverständlicher Sprache auf welche Weise sich diese Signale auf Alltag und soziale Netzwerke auswirken, und wie sie unser politisches und wirtschaftliches Leben beeinflussen.
- Published
- 2024
44. Stunting as a Synonym of Social Disadvantage and Poor Parental Education
- Author
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Andrea V. Ch. Safira, Regina Maya Manubulu, Michael Hermanussen, Sugi Deny Pranoto Soegianto, Christiane Scheffler, Tjahyo Suryanto, Debora Natalia Ndaparoka, Yohannes Dian Indrajati, Rani Rahmani, Giovanni Kathlix Immanuel Matulessy, Queen Sugih Ariyani, Maria Natalia Puteri, Taolin Fransiskus, Aman B Pulungan, Madarina Julia, Maria Kurniati Ester Payong, Samuel Yan Touw, Alexandro Valent Homalessy, Sevany Isabella Angi, and Reynardo Kurnia Hadiyanto Purba
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Social background ,economic ,political and emotional factors on growth ,Health, Toxicology and Mutagenesis ,Physical fitness ,lcsh:Medicine ,Nutritional Status ,030209 endocrinology & metabolism ,Article ,03 medical and health sciences ,0302 clinical medicine ,Parental education ,medicine ,Prevalence ,Humans ,030212 general & internal medicine ,Child growth ,Child ,Growth Disorders ,business.industry ,lcsh:R ,Malnutrition ,Public Health, Environmental and Occupational Health ,stunting ,social ,Anthropometry ,medicine.disease ,Disadvantaged ,Cross-Sectional Studies ,Indonesia ,Social disadvantage ,business ,Demography - Abstract
Socially, economically, politically and emotionally (SEPE) disadvantaged children are shorter than children from affluent background. In view of previous work on the lack of association between nutrition and child growth, we performed a study in urban schoolchildren. We measured 723 children (5.83 to 13.83 years), Kupang, Indonesia, three schools with different social background. We investigated anthropometric data, clinical signs of malnutrition, physical fitness, parental education, and household equipment. Subjective self-confidence was assessed by the MacArthur test. The prevalence of stunting was between 8.5% and 46.8%. Clinical signs of under- or malnutrition were absent even in the most underprivileged children. There was no delay in tooth eruption. Underprivileged children are physically fitter than the wealthy. The correlation between height and state of nutrition (BMI_SDS, skinfold_SDS, MUAC_SDS) ranged between r = 0.69 (p <, 0.01) and r = 0.43 (p <, 0.01) in private school children, and between r = 0.07 (ns) and r = 0.32 (p <, 0.01) in the underprivileged children. Maternal education interacted with height in affluent (r = 0.20, p <, 0.01) and in underprivileged children (r = 0.20, p <, 0.01). The shortness of SEPE disadvantaged children was not associated with anthropometric and clinical signs of malnutrition, nor with delay in physical development. Stunting is a complex phenomenon and may be considered a synonym of social disadvantage and poor parental education.
- Published
- 2021
45. Trends in growth and developmental tempo in boys aged 7 to 18 years between 1966 and 2012 in Poland
- Author
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Slawomir Koziel, Michael Hermanussen, Christiane Scheffler, Natalia Nowak-Szczepanska, and Aleksandra Gomula
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Male ,060101 anthropology ,Adolescent ,Body height ,030209 endocrinology & metabolism ,06 humanities and the arts ,Growth spurt ,Biology ,Body Height ,Adult height ,Secular variation ,03 medical and health sciences ,0302 clinical medicine ,ddc:570 ,Anthropology ,Genetics ,Humans ,0601 history and archaeology ,Poland ,Anatomy ,Child ,Institut für Biochemie und Biologie ,Ecology, Evolution, Behavior and Systematics ,Demography - Abstract
Objectives: To assess trends in growth in different developmental periods and trends in developmental tempo in Polish boys between 1966 and 2012. Methods: Data on 34 828 boys aged 7 to 18 years were collected during Polish Anthropological Surveys conducted in 1966, 1978, 1988, and 2012. Biological parameters, related to onset of adolescent growth spurt (OGS) and peak height velocity (PHV), were derived from a Preece-Baines 1 model (PB1). Childhood (height at 7 years of age), pre-adolescent (height at OGS) and adolescent growth (adult height minus height at OGS) were identified. Results: Positive secular trend between 1966 and 2012 in adult height accounted for, on average, 1.5 cm/decade, with varying intensity between the Surveys. Decline in both age at OGS and APHV between 1966 and 2012 (1.5 and 1.4 years, respectively) indicated an acceleration in developmental tempo, on average, by 0.3 year/decade. Increases in the contribution to the trend in adult height gained during growth in particular developmental periods between 1966 and 2012 were as followed-childhood: 0.6%, pre-adolescent growth: -3.1%, adolescent growth: 3.1%. Conclusions: Secular trend in developmental tempo and growth among boys reflects changes in living conditions and socio-political aspirations in Poland during nearly 50 years. Acceleration in tempo is already visible at age at OGS, whereas the trend in adult height occurs largely during adolescence, pointing to different regulation of developmental tempo and growth in body height. This finding emphasizes the importance of extending public health intervention into children's growth up until adolescence.
- Published
- 2020
- Full Text
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46. Traumatized women's infants are bigger than children of mothers without traumas
- Author
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Magdalena Piosek, Christiane Scheffler, Magdalena Babiszewska, Detlef Groth, Michael Hermanussen, Anna Apanasewicz, Patrycja Wychowaniec, Anna Ziomkiewicz, and Olga Barbarska
- Subjects
Offspring ,Early life stress ,Mothers ,Breast milk ,Affect (psychology) ,Life history theory ,03 medical and health sciences ,0302 clinical medicine ,Medicine ,Animals ,Humans ,Child ,Ecology, Evolution, Behavior and Systematics ,030304 developmental biology ,0303 health sciences ,Human studies ,Milk, Human ,business.industry ,Body Weight ,Infant ,General Medicine ,Anthropometry ,Accelerated Growth ,Anthropology ,Animal Science and Zoology ,Female ,business ,030217 neurology & neurosurgery ,Demography - Abstract
Life history theory predicts that experiencing stress during the early period of life will result in accelerated growth and earlier maturation. Indeed, animal and some human studies documented a faster pace of growth in the offspring of stressed mothers. Recent advances in epigenetics suggest that the effects of early developmental stress might be passed across the generations. However, evidence for such intergenerational transmission is scarce, at least in humans. Here we report the results of the study investigating the association between childhood trauma in mothers and physical growth in their children during the first months of life. Anthropometric and psychological data were collected from 99 mothers and their exclusively breastfed children at the age of 5 months. The mothers completed the Early Life Stress Questionnaire to assess childhood trauma. The questionnaire includes questions about the most traumatic events that they had experienced before the age of 12 years. Infant growth was evaluated based on the anthropometric measurements of weight, length, and head circumference. Also, to control for the size of maternal investment, the composition of breast milk samples taken at the time of infant anthropometric measurements was investigated. The children of mothers with higher early life stress tended to have higher weight and bigger head circumference. The association between infant anthropometrics and early maternal stress was not affected by breast milk composition, suggesting that the effect of maternal stress on infant growth was independent of the size of maternal investment. Our results demonstrate that early maternal trauma may affect the pace of growth in the offspring and, in consequence, lead to a faster life history strategy. This effect might be explained via changes in offspring epigenetics.
- Published
- 2020
47. No correlation between short term weight gain and lower leg length gain in healthy German children
- Author
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Daniel J Naumenko, Detlef Groth, Michael Hermanussen, Arusa Maqsood, and Christiane Scheffler
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Pulsatile flow ,General Medicine ,Body weight ,Term (time) ,body regions ,Correlation ,Chronic nutritional deficiency ,Animal science ,Anthropology ,medicine ,Animal Science and Zoology ,ddc:610 ,medicine.symptom ,Weight gain ,Institut für Biochemie und Biologie ,Ecology, Evolution, Behavior and Systematics ,Lower Leg Length ,Mathematics - Abstract
Background: Length-for-age is considered the indicator of choice in monitoring the long-term impact of chronic nutritional deficiency. Aim: We hypothesized that short term increments of body weight cross-correlate with increments of the lower leg length. Sample and methods: We re-analyzed the association between weekly measurements of weight and of lower leg length in 34 healthy German children, aged 2.9-15.9 years. The data are a subset of measurements originally published in 1988 (Hermanussen et al. 1988a). As the growth measurements were often not equally spaced in time due to interposed holidays and illness, the incremental rates for weight and lower leg length were smoothed using spline functions. Autocorrelation and cross-correlation functions were calculated for weight increments and lower leg length increments. Results: Height and weight increments are pulsatile. Autocorrelations indicated that mini growth spurts occur at irregular intervals. Lack of cross-correlations between weight and lower leg length indicated that mini spurts in weight gain do not coincide with mini spurts in length gain even when considering lag times of up to 10 weeks. Short term changes of weight gain and lower leg length gain in healthy children show no temporal association.
- Published
- 2020
48. The regulation of human growth includes an understanding of competitive growth strategies and community effects on height
- Author
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Christiane Scheffler, Barry Bogin, and Michael Hermanussen
- Subjects
Anthropology ,Competitive growth ,Genetics ,MEDLINE ,Anatomy ,Biology ,Ecology, Evolution, Behavior and Systematics ,Industrial organization - Published
- 2019
- Full Text
- View/download PDF
49. Environmental stimulation on height: The story from Indonesia
- Author
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Christiane Scheffler, Aman B Pulungan, Detlef Groth, Michael Hermanussen, and Susi Natalia Hasibuan
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Adult ,Male ,Adolescent ,Cross-sectional study ,Population ,010501 environmental sciences ,01 natural sciences ,Population density ,03 medical and health sciences ,0302 clinical medicine ,Humans ,030212 general & internal medicine ,Growth Charts ,education ,Child ,Ecology, Evolution, Behavior and Systematics ,0105 earth and related environmental sciences ,education.field_of_study ,Sex Characteristics ,Infant ,General Medicine ,Crowding ,language.human_language ,Adult height ,Body Height ,Indonesian ,Sexual dimorphism ,Geography ,Cross-Sectional Studies ,Indonesia ,Anthropology ,language ,Animal Science and Zoology ,Female ,Demography ,Sex characteristics - Abstract
Background: Since the 19th century, sexual dimorphism has been known to be sensitive to adverse environmental conditions. Migrants are sensitive to economic and political affluence, and tend to adjust in height towards height of their hosts. We aim to study growth, sexual dimorphism, and height of native and migrant children in three primary schools in Nabire, Papua, Indonesia. Material and Methods 1: Cross-sectional data on height were obtained from 186 children (59 and 56 native Papuan girls and boys, respectively; 38 and 33 trans-migrant girls and boys respectively; who are aged 7.0-7.7 (mean 7.45) years from three primary schools in Nabire, Papua, Indonesia. The Indonesian National Growth Charts were used as references for height. Results 1: With 118.4 cm (SD 6.7) cm, trans-migrant 7-year old boys were almost 3 cm taller compared to their native-age-matched-peers (115.7 cm (5.0 SD) cm, p < 0.05). The case was different among the girls. Trans-migrant girls were not significantly taller than native girls. Material and Method 2: We re-analyzed the height data from over 300,000 infants, children and adolescents, age 0-18 year, from 34 Indonesian provinces. The data were obtained from the latest Indonesian 2013 National Basic Health Survey (NHBS), and have previously been used to construct National Indonesian Growth Charts. St. Nicolas House Analysis was used to translate correlation matrices into network graphs and visualizing chains of associations between parameters that were multiply correlated. Results 2: St. Nicolas House Analysis suggested that the growth of male sex were more sensitive to population crowding, and that crowding contributes to the greater height dimorphism in taller populations. Conclusion: Economic prosperity and increased population density stimulate male adult height to a greater extent than female adult height, and increase the sexual dimorphism in height among the tall populations of densely populated wealthy countries.
- Published
- 2019
50. Affinity to host population stimulates physical growth in adult offspring of Turkish migrants in Germany
- Author
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Christiane Scheffler and Aydan Özer
- Subjects
Adult ,Male ,Adolescent ,Turkey ,Turkish ,Population ,Ethnic group ,Growth ,Adult offspring ,Young Adult ,Germany ,ddc:570 ,Ethnicity ,Humans ,Young adult ,education ,Institut für Biochemie und Biologie ,Ecology, Evolution, Behavior and Systematics ,Transients and Migrants ,education.field_of_study ,Host (biology) ,Social environment ,social sciences ,General Medicine ,language.human_language ,Geography ,Dominance (ethology) ,Anthropology ,language ,Adult Children ,population characteristics ,Animal Science and Zoology ,geographic locations ,Demography - Abstract
Because of political conflicts and climate change, migration will be increased worldwide and integration in host societies is a challenge also for migrants. We hypothesize that migrants, who take up the challenge in a new social environment are taller than migrants who do not pose this challenge. We analyze by a questionnaire possible social, nutritional and ethnic influencing factors to body height (BH) of adult offspring of Turkish migrants (n = 82, 39 males) aged from 18 to 34 years (mean age 24.6 years). The results of multiple regression (downward selection) show that the more a male adult offspring of Turkish migrants feels like belonging to the Turkish culture, the smaller he is (95% CI, -3.79, -0.323). Further, the more a male adult offspring of Turkish migrants feels like belonging to the German culture, the taller he is (95% CI, -0.152, 1.738). We discussed it comparable to primates taking up their challenge in dominance, where as a result their body size increase is associated with higher IGF-1 level. IGF-1 is associated with emotional belonging and has a fundamental role in the regulation of metabolism and growth of the human body. With all pilot characteristics of our study results show that the successful challenge of integration in a new society is strongly associated with the emotional integration and identification in the sense of a personal sense of belonging to society. We discuss taller BH as a signal of social growth adjustment. In this sense, a secular trend of BH adaptation of migrants to hosts is a sign of integration.
- Published
- 2018
- Full Text
- View/download PDF
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