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18 results on '"Chu, Guangdi"'

6. Telemedicine network latency management system in 5G telesurgery: a feasibility and effectiveness study

Author

Li, Chengjun, primary, Zheng, Jilu, additional, Zhang, Xin, additional, Luo, Lei, additional, Chu, Guangdi, additional, Zhao, Jianchang, additional, Zhang, Zhao, additional, Wang, Haiyun, additional, Qin, Fei, additional, Zhou, Guanzhi, additional, Jiao, Wei, additional, Wang, Yonghua, additional, Yang, Xuecheng, additional, Zhou, Zhilong, additional, Yang, Dejun, additional, Guo, Hao, additional, Zhang, Ce, additional, Li, Jianmin, additional, and Niu, Haitao, additional

Published
2023
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9. Application of Improved Robot-assisted Laparoscopic Telesurgery with 5G Technology in Urology

Author

Li, Jianmin, primary, Yang, Xuecheng, additional, Chu, Guangdi, additional, Feng, Wei, additional, Ding, Xuemei, additional, Yin, Xulong, additional, Zhang, Liangjun, additional, Lv, Wei, additional, Ma, Lufei, additional, Sun, Liguo, additional, Feng, Run, additional, Qin, Jun, additional, Zhang, Xuefeng, additional, Gou, Chengyi, additional, Yu, Zongyi, additional, Wei, Bin, additional, Jiao, Wei, additional, Wang, Yonghua, additional, Luo, Lei, additional, Yuan, Hang, additional, Chang, Yuan, additional, Cai, Qiliang, additional, Wang, Shuxin, additional, Giulianotti, Pier Cristoforo, additional, Dong, Qian, additional, and Niu, Haitao, additional

Published
2023
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13. Prognostic Value of Preoperative Albumin-to-Alkaline Phosphatase Ratio in Patients with Muscle-Invasive Bladder Cancer After Radical Cystectomy

Author

Zhao,Ming, Zhang,Mingxin, Wang,Yonghua, Yang,Xuecheng, Teng,Xue, Chu,Guangdi, Wang,Xinsheng, Niu,Haitao, Zhao,Ming, Zhang,Mingxin, Wang,Yonghua, Yang,Xuecheng, Teng,Xue, Chu,Guangdi, Wang,Xinsheng, and Niu,Haitao

Abstract

Ming Zhao,1,* Mingxin Zhang,2,* Yonghua Wang,2 Xuecheng Yang,2 Xue Teng,2 Guangdi Chu,2,3 Xinsheng Wang,2 Haitao Niu2 1Department of Urology, Qingdao 8th People’s Hospital, Qingdao, People’s Republic of China; 2Department of Urology, The Affiliated Hospital of Qingdao University, Qingdao, People’s Republic of China; 3Department of Clinical Medicine, Qingdao University, Qingdao, People’s Republic of China*These authors contributed equally to this workCorrespondence: Haitao Niu; Xinsheng Wang Email niuht0532@126.com; Wangxs0532@163.comObjective: This study investigated the prognostic value of the preoperative albumin alkaline phosphatase ratio (AAPR) in patients with muscle-invasive bladder cancer after radical cystectomy.Materials and Methods: We performed a retrospective, single-center cohort study among patients with muscle-invasive bladder cancer who underwent radical cystectomy and urinary diversion at the Department of Urology Surgery of the Affiliated Hospital of Qingdao University from 2007 to 2015. Cox proportional hazards regression was used to evaluate the relationship between preoperative AAPR and outcomes which include OS and CSS and RFS. Survival analysis was conducted using the Kaplan–Meier method and the log rank test.Results: In total, 174 patients were followed up for 1– 125 months, with a median follow-up of 30 months, 93 survived and 81 patients died. The median serum AAPR level in all patients was 0.62 (range: 0.12– 1.67). In multivariate analysis, the preoperative AAPR showed to be associated with overall survival (OS: HR 0.22,95% CI 0.06 to 0.82, P=0.024), cancer-specific survival (CSS: HR 0.12,95% CI 0.02 to 0.63, P=0.013) and recurrence-free survival (RFS: HR 0.15,95% CI 0.03 to 0.82, P=0.029) after adjustment for potential confounders. Kaplan–Meier analysis showed that patients with low AAPR tertiles had shorter OS, CSS and RFS than patients with high AAPR tertile

Published
2020

18. SLC16A3 is a Prognostic Marker and Affects Immune Regulation in Bladder Cancer.

Author

Li C, Chu G, Ma G, Chen X, Ma X, and Niu H

Abstract

Background: Overexpression of SLC16A3 can contribute to the development of various tumors by regulating metabolism, but a systematic analysis of SLC16A3 in bladder cancer (BC) has been rarely reported., Methods: We used the BC datasets from public databases to investigate SLC16A3 expression in BC. We first analysed the relationship between SLC16A3 expression and clinical characteristics of 412 bladder cancer patients. After that, gene function analyses and immunocorrelation analyses of SLC16A3 were conducted with the R package. For immunotherapy effect and drug sensitivity analysis, we also used the R package. We also analysed the relation between SLC16A3 expression and 20 m6A modification key genes. Finally, we determined the expression localization of SLC16A3 in bladder cancer by single-cell sequencing analysis using 3,115 BC cells. We further detected the expression of SLC16A3/MCT4 on BC samples by reversed transcriptionquantitative polymerase chain reaction and immunohistochemistry., Results: The SLC16A3 was overexpressed in BC cells, including epithelial cells (p＜0.001). The high SLC16A3 expression level of patients with BC was significantly related to poor prognosis (p＝0.044), and we established a reliable prognosis model for BC patients. Statistically significant associations between SLC16A3 and m6A modification (ALKBH5) gene (p＜0.001), key genes in aerobic glycolysis, M2 macrophage infiltration (p＝0.0058), and immune checkpoint regulation were observed., Conclusion: Overexpression of SLC16A3 is an independent prognostic factor in patients with BC. SLC16A3 may influence the immune infiltration of BC by regulating BC metabolism and m6A methylation, which ultimately can lead to the progress of BC. For the detection and therapy of BC, SLC16A3 may be a potent therapeutic target for BC., (Copyright© Bentham Science Publishers; For any queries, please email at epub@benthamscience.net.)

Published
2024
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