1. Pathogen-Specific Effects of Probiotics in Children With Acute Gastroenteritis Seeking Emergency Care: A Randomized Trial.
- Author
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Freedman, Stephen B, Finkelstein, Yaron, Pang, Xiao Li, Chui, Linda, Tarr, Phillip I, VanBuren, John M, Olsen, Cody, Lee, Bonita E, Hall-Moore, Carla A, Sapien, Robert, O'Connell, Karen, Levine, Adam C, Poonai, Naveen, Roskind, Cindy, Schuh, Suzanne, Rogers, Alexander, Bhatt, Seema, Gouin, Serge, Mahajan, Prashant, Vance, Cheryl, Hurley, Katrina, Powell, Elizabeth C, Farion, Ken J, and Schnadower, David
- Subjects
Biomedical and Clinical Sciences ,Clinical Sciences ,Emerging Infectious Diseases ,Complementary and Integrative Health ,Clinical Trials and Supportive Activities ,Foodborne Illness ,Prevention ,Pediatric ,Infectious Diseases ,Clinical Research ,Nutrition ,Biotechnology ,Digestive Diseases ,Infection ,Good Health and Well Being ,Canada ,Child ,Diarrhea ,Double-Blind Method ,Emergency Medical Services ,Gastroenteritis ,Humans ,Infant ,Lactobacillus helveticus ,Lacticaseibacillus rhamnosus ,Probiotics ,child ,probiotic ,gastroenteritis ,diarrhea ,emergency service ,hospital ,Biological Sciences ,Medical and Health Sciences ,Microbiology ,Clinical sciences - Abstract
BackgroundIt is unknown if probiotics exert pathogen-specific effects in children with diarrhea secondary to acute gastroenteritis.MethodsAnalysis of patient-level data from 2 multicenter randomized, placebo controlled trials conducted in pediatric emergency departments in Canada and the United States. Participants were 3-48 months with >3 diarrheal episodes in the preceding 24 hours and were symptomatic for
- Published
- 2022