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A simple and efficient gold-catalyzed coupling of secondary amine with phenylglyoxal derivatives has been developed, which provides a practical synthetic strategy for the synthesis of substituted α-ketoamides under mild reaction conditions.

Internal tides generated upon two-dimensional Gaussian topographies of different sizes and steepness are investigated theoretically in a numerical methodology. Compared with previous theoretical works, this model is not restricted by weak topography, but provides an opportunity to examine the influence of topography. Ten typical cases are studied using different values of height and/or width of topography. By analyzing the baroclinic velocity fields, as well as their first eight baroclinic modes, it is found that the magnitude of baroclinic velocity increases and the vertical structure becomes increasingly complex as height increases or width decreases. However, when both height and width vary, while parameter s (the ratio of the topographic slope to the characteristic slope of the internal wave ray) remains invariant, the final pattern is influenced primarily by width. The conversion rate is studied and the results indicate that width determines where the conversion rate reaches a peak, and where it is positive or negative, whereas height affects only the magnitude. High and narrow topography is considerably more beneficial to converting energy from barotropic to baroclinic fields than low and wide topography. Furthermore, parameter s, which is an important non-dimensional parameter for internal tide generation, is not the sole parameter by which the baroclinic velocity fields and conversion rate are determined.

Seasonal variations of baroclinic tides for K1 and M2 constituents were separately studied using two-dimensional numerical simulations along the 21°N section of the northern South China Sea (SCS). Results show that the continental slope of the northern SCS and the west ridge of the Luzon Strait are supercritical to K1 internal tides, which may be trapped in the deep basin of the SCS and form standing or partial standing waves. Meanwhile, these areas are sub-critical to M2 internal tides, which can transmit onto the shelf and are seldom reflected back into the basin. The trapped K1 internal tides are dominated by mode-2 and mode-3 in summer and by mode-1 and mode-3 in winter. Moreover, high mode K1 internal tides account for nearly 20–40 % of the total energy density in winter and 15–20 % in summer. The pattern of K1 internal tides in the basin is mainly determined by the percentage of reflected energy from the continental slope. The phase difference between the incoming mode-1 and mode-2 K1 internal tides near the continental slope are nearly out of phase in winter, which means that the percentage of reflection of the K1 internal tide is larger than that in summer. Both the convergence and high mode K1 internal tides can enhance the vertical shear. The above results indicate that, in the deep basin of the SCS, water mixing potentially induced by internal tides in winter is stronger than in summer.

A three-dimensional isopycnic-coordinate ocean model for the study of internal tides is presented. In this model, the ocean interior is viewed as a stack of isopycnic layers, each characterized by a constant density. The isopycnic coordinate performs well at tracking the depth variance of the thermocline, and is suitable for simulation of internal tides. This model consists of external and internal modes, and barotropic and baroclinic motions are calculated in the two modes, respectively. The capability of simulating internal tides was verified by comparing model results with an analytical solution. The model was then applied to the simulation of internal tides in the South China Sea (SCS) with the forcing of M2 and K1 tidal constituents. The results show that internal tides in the SCS are mainly generated in the Luzon Strait. The generated M2 internal tides propagate away in three different directions (branches). The branch with the widest tidal beam propagates eastward into the Pacific Ocean, the most energetic branch propagates westward toward Dongsha Island, and the least energetic branch propagates southwestward into the basin of the SCS. The generated K1 internal tides propagate in two different directions (branches). One branch propagates eastward into the Pacific Ocean, and the other branch propagates southwestward into the SCS basin. The steepening process of internal tides due to shoaling effects is described briefly. Meridionally integrated westward energy fluxes into the SCS are comparable to the meridionally integrated eastward energy fluxes into the Pacific Ocean.

Amphoteric polyacrylamide (AmPAM) was prepared successfully through seeded dispersion polymerization with acrylamide, methacrylatoethyl trimethyl ammonium chloride and acrylic acid as comonomers in ammonium sulfate solution. It was characterized by 1H nuclear magnetic resonance (1H NMR) and elemental analysis. The particle morphology and apparent viscosity of polymer dispersion were obtained by optical microscope and rotary viscometer, respectively. AmPAM dispersion was obtained with low apparent viscosity. The process was smooth without high viscosity stage. The data of 1H NMR spectrum and elemental analysis indicated that all monomers had participated in the polymerization. The seeded reaction time and the mass ratio of two parts of monomers had significant effects on the dispersion polymerization. The best conditions were seeded reaction time 1.75h and the mass ratio 0.75. The apparent viscosity of AmPAM dispersion depended on the number of particles, particle size and low molecular weight polymer concentration in the continuous phase. AmPAM showed both anti-polyelectrolyte effect and polyelectrolyte effect. POLYM. ENG. SCI., 2011. © 2011 Society of Plastics Engineers

Chitosan derived from crab shells, was used to prepare the graft polymer in aqueous solution with acrylamide (AM) and methacrylatoethyl trimethyl ammonium chloride (DMC) as raw materials and ceric ammonium nitrate (CAN) as initiator. The flocculation ability of the resulting polymer (PCAD) was studied in waste water treatment experiments. Its properties were determined on the basis of the transmittance of waste water after flocculation. The effects of chitosan and DMC content on PCAD’s flocculation ability were studied. Flocculation experiments were also undertaken under various pH conditions. According to the experimental data, the flocculation ability could be improved when chitosan content decreased in the raw material, but the monomer conversion would decrease obviously. When the chitosan’s content was more than 65%, AM and DMC groups were less on each chitosan molecule. So PCAD’s flocculation ability was poor. Similarly, high content of DMC would result in low monomer conversion and high flocculation ability. PCAD molecules with more DMC group had more positive charges. It was favorable to flocculation. However, monomer conversion would decrease with the increase of DMC content. The suitable conditions were that chitosan and DMC contents were 65% and 15–20%, respectively. The experiment data showed that PCAD had good flocculation ability under weak acidic condition. Its ability would be weakened by strong acidic or alkaline condition. The flocculation efficiency was the best at pH of 5.5 when PCAD’s dosage was 8mg·L−1. Compared with cationic polymer (the copolymer of AM and DMC, PAD), PCAD showed better flocculation ability under acid and neutral conditions, but worse ability under alkaline condition.

The bis‐oxanthene, bis‐polyhydroacridine, and bis‐N‐hydroxylacridine derivatives were obtained by the reaction of aromatic dialdehyde with dimedone in ethylene glycol under microwave irradiation. The reaction time was shot and the yield was high.

The procedure can be applied to various arylglyoxals and some amines to afford the desired substructures with good to excellent yield.

Based on an internal tidal model, the practical performances of the limited-memory BFGS (L-BFGS) method and two gradient descent (GD) methods (the normal one with Wolfe’s line search and the simplified one) are investigated computationally through a series of ideal experiments in which the open boundary conditions (OBCs) are inverted by assimilating the interior observations with the adjoint method. In the case that the observations closer to the unknown boundary are included for assimilation, the L-BFGS method performs the best. As compared with the simplified GD method, the normal one really uses less iteration to reach a satisfactory solution, but its advantage over the simplified one is much smaller than expected. In the case that only the observations that are further from the unknown boundary are assimilated, the simplified GD method performs the best instead, whereas the performances of the other two methods are not satisfactory. The advanced L-BFGS algorithm and Wolfe’s line search still need to be improved when applied to the practical cases. The simplified GD method, which is controllable and easy to implement, should be regarded seriously as a choice, especially when the classical advanced optimization techniques fail or perform poorly.

The title compound, C(28)H(28)N(2)O(5), consists of a partially hydrogenated acridine ring system with two substituted phenyl substituents on the dihydro-pyridine ring which are both nearly perpendicular to the mean plane of the acridine unit [dihedral angles of 81.3 (1) and 89.6 (1)° between the central ring of acridine and the methoxyphenyl and nitrophenyl rings, respectively]. The dihydro-pyridine ring is almost planar, whereas both the outer unsymmetrical six-membered rings adopt half-chair conformations.

A series of bis‐1,4‐dihydropyridine derivatives were synthesized by the reaction of p‐phenylenedialdehyde or m‐phenylenedialdehyde and active methylene compounds.

The reaction of aldeoxime with dimedone and ammonium acetate in glycol under microwave irradiation has been carried out, elimination and cyclization happened and acridine derivatives were obtained. The structure of the product has been thoroughly studied by x‐ray crystallographic analysis.

A novel sequential addition, elimination and cyclization reactions took place when aldoxime and dimedone in glycol was subjected to microwave irradiation and a new type of N-hydroxyl-acridinedione derivatives was obtainedin excellent yields (80-95%) within a short reaction time (4-8 min).

A simple effective synthesis of 3,4-dihydropyrimidin-2(1H)-one derivatives, using boric acid as catalyst, from aromatic aldehydes, 1,3-dicarbonyl compounds and urea in glacial acetic acid is described. Compared with the classical Biginelli reaction conditions, this new method has the advantage of excellent yields (86–97%) and short reaction time (0.5–2 h).

The synthesis of bifunctional pyridine, pyrimidine, pyridone, quinoline and acridine derivatives was investigated using dialdehyde as a precursor. A rapid and efficient method was developed for the synthesis of a range of bifunctional monocyclic, bicyclic and tricyclic products related to 1,4-DHPs with the aim of finding new classes of biologically active compounds.

A simple effective synthesis of 3,4-dihydropyrimidin-2(1 H)-one derivatives from aromatic aldehydes, 1,3-dicarbonyl compounds and urea in glacical acetic acid using cadmium sulfate as catalyst is described and compared with the classical Biginelli reaction conditions, this new method has the advantage of excellent yields (83–94%) and short reaction time (2-4 h).