5 results on '"Cirisano, Anastasia"'
Search Results
2. Diagnosis and management of urinary tract infections in children aged 2 months to 3 years in the Italian emergency units: the ItaUTI study.
- Author
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Cenzato, Francesca, Milani, Gregorio P., Amigoni, Angela, Sperotto, Francesca, Bianchetti, Mario G., Agostoni, Carlo, Montini, Giovanni, on behalf of the ItaUTI study group, Farello, Giovanni, Chiarelli, Francesco, Greco, Rita, Di Lollo, Franco, Rocco Forte, Fabio, Manieri, Sergio, Carpino, Luigi, Caloiero, Mimma, Cirisano, Anastasia, Braghò, Salvatore, Della Casa, Roberto, and Nunziata, Felice
- Abstract
Urinary tract infections (UTIs) are among the most frequent bacterial diseases in infants and children. Physician adherence to recommendations is notoriously often poor, but no data are available on UTIs management in the emergency setting. In this multicenter national study, we investigated the policies regarding UTIs management in children aged 2 months to 3 years in Italian emergency units. Between April and June 2021, directors of the emergency units were invited to answer an online survey on the following items: diagnostic approach to children with fever without an apparent source, therapeutic approach to UTIs, the use of kidney and urinary tract ultrasound, and the criteria for hospitalization. A total of 121 (89%) out of 139 of invited units participated in the study. Overall, units manage children with a suspected or confirmed UTI according to available recommendations for most of the items. However, in almost 80% (n = 94) of units, a sterile perineal bag is used to collect urine for culture. When urine is collected by cathether, heterogeneity exists on the threshold of bacterial load considered for UTI diagnosis. Conclusions: Available recommendations on UTIs in children are followed by Italian emergency units for most of the items. However, the methods to collect urine specimens for culture, one of the crucial steps of the diagnostic work-up, often do not align with current recommendations and CFU thresholds considered for diagnosis largely vary among centers. Efforts should be addressed to validate and implement new child and family friendly urine collection techniques. What is Known: • Several guidelines are published on the management of children with suspected or confirmed urinary tract infection. • No data are available on the management of pediatric urinary tract infections in the emergency setting. What is New: • Almost 80% of the Italian emergency units employ a sterile perineal bag to collect urine for culture. • Diagnostic CFU thresholds largely vary among centers. [ABSTRACT FROM AUTHOR]
- Published
- 2022
- Full Text
- View/download PDF
3. Correction: Diagnosis and management of urinary tract infections in children aged 2 months to 3 years in the Italian emergency units: the ItaUTI study.
- Author
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Cenzato, Francesca, Milani, Gregorio P., Amigoni, Angela, Sperotto, Francesca, Bianchetti, Mario G., Agostoni, Carlo, Montini, Giovanni, on behalf of the ItaUTI study group, Farello, Giovanni, Chiarelli, Francesco, Greco, Rita, Di Lollo, Franco, Rocco Forte, Fabio, Manieri, Sergio, Carpino, Luigi, Caloiero, Mimma, Cirisano, Anastasia, Braghò, Salvatore, Della Casa, Roberto, and Nunziata, Felice
- Abstract
A correction is presented to the article "Diagnosis and management of urinary tract infections in children aged 2 months to 3 years in the Italian emergency units: the ItaUTI study" which appeared in the June 16, 2022 issue.
- Published
- 2022
- Full Text
- View/download PDF
4. Prevalence and Clinical Relevance of IgE Sensitization to Profilin in Childhood: A Multicenter Study
- Author
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Dondi, A, Tripodi, S, Panetta, V, Asero, R, Businco, Ad, Bianchi, A, Carlucci, A, Ricci, G, Bellini, F, Maiello, N, del Giudice, Mm, Frediani, T, Sodano, S, Dello Iacono, I, Macrì, F, Massaccesi, V, Caffarelli, C, Rinaldi, L, Patria, Mf, Varin, E, Peroni, Diego, Chinellato, I, Chini, L, Moschese, V, Lucarelli, S, Bernardini, R, Pingitore, G, Pelosi, U, Tosca, M, Paravati, F, La Grutta, S, Meglio, P, Calvani, M, Plebani, M, Matricardi, Pm, Asero, Riccardo, Tripodi, Salvatore, Dondi, Arianna, Di Rienzo Businco, Andrea, Sfika, Ifigenia, Bianchi, Annamaria, Candelotti, Paolo, Caffarelli, Carlo, Povesi Dascola, Carlotta, Ricci, Giampaolo, Calamelli, Elisabetta, Maiello, Nunzia, MIRAGLIA DEL GIUDICE, Michele, Frediani, Tullio, Frediani, Simone, Macri, Francesco, Moretti, Matteo, Iacono, Iride Dello, Patria, Maria Francesca, Varin, Elena, Peroni, Diego, Comberiati, Pasquale, Chini, Loredana, Moschese, Viviana, Lucarelli, Sandra, Bernardini, Roberto, Pingitore, Giuseppe, Pelosi, Umberto, Tosca, Mariangela, Cirisano, Anastasia, Faggian, Diego, Plebani, Mario, Verga, Carmen, Matricardi, Paolo Maria, and Del Giudice, Michele Miraglia
- Subjects
Male ,Allergy ,Profilin ,Prevalence ,Immunoglobulin E ,Allergic rhinitis ,Children ,Component-resolved diagnosis ,IgE ,Oral allergy syndrome ,Panallergens ,Pollen ,Allergens ,Antigens, Plant ,Carrier Proteins ,Child ,Cross Reactions ,Cucumis sativus ,Female ,Fruit ,Humans ,Hypersensitivity ,Italy ,Poaceae ,Profilins ,Rhinitis, Allergic, Seasonal ,Risk Factors ,Skin Tests ,Immunology and Allergy ,Immunology ,Medicine (all) ,Epidemiology ,Outpatient clinic ,Sensitization ,Rhinitis ,Skin Test ,biology ,Allergen ,food and beverages ,General Medicine ,medicine.anatomical_structure ,Cross Reaction ,Human ,medicine.medical_specialty ,Allergic rhinitis, Children, Component-resolved diagnosis, IgE , Oral allergy syndrome, Panallergens, Pollen, Profilin ,Socio-culturale ,macromolecular substances ,Component-resolved diagnosi ,Allergic ,Allergic rhiniti ,medicine ,Antigens ,Settore MED/38 - Pediatria Generale e Specialistica ,Seasonal ,business.industry ,Risk Factor ,Plant ,medicine.disease ,Cucumis sativu ,biology.protein ,Panallergen ,Carrier Protein ,business - Abstract
Background: Little is known about the prevalence and clinical relevance of hypersensitivity to the plant panallergen profilin in children. Objectives: The present study aimed to investigate prevalence, risk factors and clinical relevance of profilin sensitization in a large cohort of Italian children of different ages living in different geographic areas. Methods: Children with pollen allergy enrolled by 16 pediatric outpatient clinics sited in three main geographic areas of Italy were studied. SPT were carried out with commercial pollen extracts and a commercial purified date palm pollen profilin. IgE specific for allergenic pollen molecules, Phl p 12 (grass profilin) and Pru p 3 (peach lipid transfer protein) were tested by ImmunoCAP FEIA. Results: IgE to Phl p 12 (≥0.35 kU/l) was observed in 296 of the 1,271 participants (23%), including 17 of the 108 (16%) preschool children. Profilin SPT was positive (≥3 mm) in 320/1,271 (25%) participants. The two diagnostic methods were concordant in 1,151 (91%, p < 0.0001) cases. Phl p 12 IgE prevalence declined from northern to southern Italy and was directly associated with IgE to Phl p 1 and/or Phl p 5 and Ole e 1. Among children with IgE to Phl p 12, OAS was provoked by kiwi, melon, watermelon, banana, apricot and cucumber. Conclusions: Profilin sensitization is very frequent among pollen-allergic children, occurs at a very young age and contributes to the development of childhood OAS with a typical pattern of offending foods. Pediatricians should always consider IgE sensitization to profilin while examining pollen-allergic children, even if they are at preschool age.
- Published
- 2015
5. Prevalence and Clinical Relevance of IgE Sensitization to Profilin in Childhood: A Multicenter Study.
- Author
-
Asero R, Tripodi S, Dondi A, Di Rienzo Businco A, Sfika I, Bianchi A, Candelotti P, Caffarelli C, Povesi Dascola C, Ricci G, Calamelli E, Maiello N, Miraglia Del Giudice M, Frediani T, Frediani S, Macrì F, Moretti M, Dello Iacono I, Patria MF, Varin E, Peroni D, Comberiati P, Chini L, Moschese V, Lucarelli S, Bernardini R, Pingitore G, Pelosi U, Tosca M, Cirisano A, Faggian D, Plebani M, Verga C, and Matricardi PM
- Subjects
- Carrier Proteins immunology, Child, Cross Reactions immunology, Cucumis sativus immunology, Female, Fruit immunology, Humans, Italy, Male, Poaceae immunology, Prevalence, Rhinitis, Allergic, Seasonal immunology, Risk Factors, Skin Tests methods, Allergens immunology, Antigens, Plant immunology, Hypersensitivity epidemiology, Hypersensitivity immunology, Immunoglobulin E immunology, Pollen immunology, Profilins immunology
- Abstract
Background: Little is known about the prevalence and clinical relevance of hypersensitivity to the plant panallergen profilin in children., Objectives: The present study aimed to investigate prevalence, risk factors and clinical relevance of profilin sensitization in a large cohort of Italian children of different ages living in different geographic areas., Methods: Children with pollen allergy enrolled by 16 pediatric outpatient clinics sited in three main geographic areas of Italy were studied. SPT were carried out with commercial pollen extracts and a commercial purified date palm pollen profilin. IgE specific for allergenic pollen molecules, Phl p 12 (grass profilin) and Pru p 3 (peach lipid transfer protein) were tested by ImmunoCAP FEIA., Results: IgE to Phl p 12 (≥0.35 kU/l) was observed in 296 of the 1,271 participants (23%), including 17 of the 108 (16%) preschool children. Profilin SPT was positive (≥3 mm) in 320/1,271 (25%) participants. The two diagnostic methods were concordant in 1,151 (91%, p < 0.0001) cases. Phl p 12 IgE prevalence declined from northern to southern Italy and was directly associated with IgE to Phl p 1 and/or Phl p 5 and Ole e 1. Among children with IgE to Phl p 12, OAS was provoked by kiwi, melon, watermelon, banana, apricot and cucumber., Conclusions: Profilin sensitization is very frequent among pollen-allergic children, occurs at a very young age and contributes to the development of childhood OAS with a typical pattern of offending foods. Pediatricians should always consider IgE sensitization to profilin while examining pollen-allergic children, even if they are at preschool age., (© 2015 S. Karger AG, Basel.)
- Published
- 2015
- Full Text
- View/download PDF
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