Francesca Marini, Giovanni Iolascon, Francesca Giusti, Emanuela Basilici Zanetti, Cecilia Rao, Luisella Cianferotti, Umberto Tarantino, Eleonora Piccirilli, Rosaria Alvaro, Maria Luisa Brandi, Simone Parri, Antimo Moretti, Francesca Gimigliano, Noemi Cittadini, Dario Calafiore, Gemma Marcucci, Laura Masi, Giuseppe Toro, Maurizio Feola, Giuseppina Resmini, Tarantino, Umberto, Iolascon, Giovanni, Cianferotti, Luisella, Masi, Laura, Marcucci, Gemma, Giusti, Francesca, Marini, Francesca, Parri, Simone, Feola, Maurizio, Rao, Cecilia, Piccirilli, Eleonora, Zanetti, Emanuela Basilici, Cittadini, Noemi, Alvaro, Rosaria, Moretti, Antimo, Calafiore, Dario, Toro, Giuseppe, Gimigliano, Francesca, Resmini, Giuseppina, and Brandi, Maria Luisa
Background: The Italian Society for Orthopaedics and Traumatology conceived this guidance—which is primarily addressed to Italian orthopedic surgeons, but should also prove useful to other bone specialists and to general practitioners—in order to improve the diagnosis, prevention, and treatment of osteoporosis and its consequences. Materials and methods: Literature reviews by a multidisciplinary team. Results: The following topics are covered: the role of instrumental, metabolic, and genetic evaluations in the diagnosis of osteoporosis; appraisal of the risk of fracture and thresholds for intervention; general strategies for the prevention and treatment of osteoporosis (primary and secondary prevention); the pharmacologic treatment of osteoporosis; the setting and implementation of fracture liaison services for tertiary prevention. Grade A, B, and C recommendations are provided based on the main levels of evidence (1–3). Toolboxes for everyday clinical practice are provided. Conclusions: The first up-to-date Italian guidelines for the primary, secondary, and tertiary prevention of osteoporosis and osteoporotic fractures are presented. Background The Italian Society for Orthopaedics and Traumatology conceived this guidance-which is primarily addressed to Italian orthopedic surgeons, but should also prove useful to other bone specialists and to general practitioners-in order to improve the diagnosis, prevention, and treatment of osteoporosis and its consequences.Materials and methods Literature reviews by a multidisciplinary team.Results The following topics are covered: the role of instrumental, metabolic, and genetic evaluations in the diagnosis of osteoporosis; appraisal of the risk of fracture and thresholds for intervention; general strategies for the prevention and treatment of osteoporosis (primary and secondary prevention); the pharmacologic treatment of osteoporosis; the setting and implementation of fracture liaison services for tertiary prevention. Grade A, B, and C recommendations are provided based on the main levels of evidence (1-3). Toolboxes for everyday clinical practice are provided.Conclusions The first up-to-date Italian guidelines for the primary, secondary, and tertiary prevention of osteoporosis and osteoporotic fractures are presented.