584 results on '"Clarys P"'
Search Results
2. The effect of local cryotherapy on subjective and objective recovery characteristics following an exhaustive jump protocol
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Hohenauer E, Clarys P, Baeyens JP, and Clijsen R
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Cryotherapy ,cold-cuff ,muscle damage ,recovery ,Sports medicine ,RC1200-1245 - Abstract
Erich Hohenauer,1-3 Peter Clarys,3 Jean-Pierre Baeyens,2-4 Ron Clijsen,1-31Department of Business Economics, Health and Social Care, University of Applied Sciences and Arts of Southern Switzerland, Landquart, Switzerland; 2University College Physiotherapy, Thim van der Laan, Landquart, Switzerland; 3Faculty of Physical Education and Physiotherapy, Vrije Universiteit Brussel, Brussels, Belgium; 4Faculty of Medicine and Health Sciences, University of Antwerp, Antwerp, BelgiumAbstract: The purpose of this controlled trial was to investigate the effects of a single local cryotherapy session on the recovery characteristics over a period of 72 hours. Twentytwo young and healthy female (n=17; mean age: 21.9±1.1 years) and male (n=5;mean age:25.4±2.8 years) adults participated in this study. Following an exhaustive jump protocol (3×30 countermovement jumps), half of the participants received either a single local cryotherapy application (+8°C) or a single local thermoneutral application (+32°C) of 20-minute duration using two thigh cuffs. Subjective measures of recovery (delayed-onset muscle soreness and ratings of perceived exertion) and objective measures of recovery (vertical jump performanceand peak power output) were assessed immediately following the postexercise applications (0 hours) and at 24 hours, 48 hours, and 72 hours after the jump protocol. Local cryotherapy failed to significantly affect any subjective recovery variable during the 72-hour recovery period (P>0.05). After 72 hours, the ratings of perceived exertion were significantly lower in the thermoneutral group compared to that in the cryotherapy group (P=0.002). No significant differences were observed between the cryotherapy and the thermoneutral groups with respect to any of the objective recovery variables. In this experimental study, a 20-minute cryotherapy cuff application failed to demonstrate a positive effect on any objective measures of recovery. The effects of local thermoneutral application on subjective recovery characteristics were superior when compared to the effects of local cryotherapy application at 72 hours postapplication. Keywords: cryotherapy, cold cuff, muscle damage, recovery
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- 2016
3. In vivo determination of the diclofenac skin reservoir: comparison between passive, occlusive, and iontophoretic application
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Clijsen R, Baeyens JP, Barel AO, and Clarys P
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Therapeutics. Pharmacology ,RM1-950 - Abstract
Ron Clijsen,1,2 Jean Pierre Baeyens,2 André Odilon Barel,2 Peter Clarys2 1Department of Health Sciences, University of Applied Sciences and Arts of Southern Switzerland, Landquart, Switzerland; 2Faculty of Physical Education and Physiotherapy, Vrije Universiteit Brussel, Brussels, Belgium Aim: There is scarce information concerning the pharmacodynamic behavior of topical substances used in the physiotherapy setting. The aim of the present study was to estimate the formation and emptying of the diclofenac (DF) skin reservoir after passive, semiocclusive, and electrically assisted applications of DF.Subjects and methods: Five different groups of healthy volunteers (ntotal=60, 23 male and 37 female), participated in this study. A 1% DF (Voltaren Emulgel) formulation (12 mg) was applied on the volar forearms on randomized defined circular skin areas of 7 cm2. DF was applied for 20 minutes under three different conditions at the same time. The presence of DF in the skin results in a reduction of the methyl nicotinate (MN) response. To estimate the bioavailability of DF in the skin, MN responses at different times following initial DF application (1.5, 6, 24, 32, 48, 72, 96, and 120 hours) were analyzed.Results: At 1.5 hours after the initial DF application, a significant decrease in MN response was detected for the occluded and iontophoretic delivery. Passive application resulted in a decrease of the MN response from 6 hours post-DF application. The inhibition remained up to 32 hours post-DF application for the iontophoretic delivery, 48 hours for the occluded application, and 72 hours for the passive delivery. At 96 and 120 hours post-DF application none of the MN responses was inhibited.Conclusion: The formation and emptying of a DF skin reservoir was found to be dependent on the DF-application mode. Penetration-enhanced delivery resulted in a faster emptying of the reservoir. Keywords: transdermal drug delivery, passive diffusion, occlusion, iontophoresis, diclofenac
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- 2015
4. The impact of COVID-19 lockdown on physical activity and sedentary behaviour in secondary school teachers: a prospective cohort study
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Verhavert, Yanni, Deliens, Tom, Stas, Lara, Van Hoof, Elke, Deforche, Benedicte, Aerenhouts, Dirk, Clarys, Peter, Zinzen, Evert, and De Martelaer, Kristine
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- 2024
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5. Author Correction: Associations of lifestyle with burnout risk and recovery need in Flemish secondary schoolteachers: a cross-sectional study
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Verhavert, Yanni, Deliens, Tom, Van Cauwenberg, Jelle, Van Hoof, Elke, Matthys, Christophe, de Vries, Juriena, Clarys, Peter, De Martelaer, Kristine, and Zinzen, Evert
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- 2024
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6. Associations of lifestyle with burnout risk and recovery need in Flemish secondary schoolteachers: a cross-sectional study
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Verhavert, Yanni, Deliens, Tom, Van Cauwenberg, Jelle, Van Hoof, Elke, Matthys, Christophe, de Vries, Juriena, Clarys, Peter, De Martelaer, Kristine, and Zinzen, Evert
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- 2024
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7. Author Correction: Impact of Plasmodium vivax malaria on executive and cognitive functions in elderlies in the Brazilian Amazon
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Pessoa, Rockson C., Oliveira-Pessoa, Gabriela F., Souza, Brenda K. A., Sampaio, Vanderson S., Pinto, André Luiz C. B., Barboza, Larissa L., Mouta, Gabriel S., Silva, Emanuelle Lira, Melo, Gisely C., Monteiro, Wuelton M., Silva-Filho, José H., Lacerda, Marcus V. G., and Baía-da-Silva, Djane Clarys
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- 2024
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8. The impact of COVID-19 lockdown on physical activity and sedentary behaviour in secondary school teachers: a prospective cohort study
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Yanni Verhavert, Tom Deliens, Lara Stas, Elke Van Hoof, Benedicte Deforche, Dirk Aerenhouts, Peter Clarys, Evert Zinzen, and Kristine De Martelaer
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Confinement ,Quarantine ,Energy expenditure ,Longitudinal ,Pandemic ,Teachers ,Public aspects of medicine ,RA1-1270 - Abstract
Abstract Background Mid-March 2020, Belgium went in lockdown to combat the COVID-19-pandemic. Having to provide school-based day care and adapt to online teaching, while all social, cultural and sports events and activities were cancelled, secondary school teachers’ physical activity (PA) and sedentary behaviour (SB) may have been affected considerably. This study investigates the impact of the first Belgian lockdown on PA and SB in Flemish secondary school teachers. Methods This prospective cohort study was conducted throughout the 2019–2020 school year. PA and SB measured in March/April 2020 were compared with a pre-lockdown measurement in January/February 2020. Other pre-lockdown measurements (September/October 2019 and November/December 2019) and one other during-lockdown measurement (May/June 2020) allowed us to control for confounding. Validated questionnaires were used to assess participants’ PA and SB. Generalized linear mixed models were applied in R. Results Among 624 participants (77·2% females, 43·3 ± 10·3 years), increases were observed for total PA (+ 108 min/week; p = 0·047), moderate PA (+ 217 min/week; p = 0·001), domestic and garden PA (+ 308 min/week; p
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- 2024
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9. Autocoleta vaginal por mulheres vivendo com HIV/AIDS para testagem de HPV-DNA: implantação piloto no Brasil
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Pamela Gaspar, Hanalydia de Melo Machado, Maria Luiza Bazzo, Aline Scherer, Álvaro Luis Colusso, Ana Gabriela Álvares Travassos, Denise Arakaki-Sanchez, Djane Clarys Baia-da-Silva, Eduardo Campos de Oliveira, Isabella Ribeiro Zago, Marcos de Assis Moura, Marcus Vinicius Guimarães de Lacerda, Simone Murta Martins, Tânia Reuter, Valdir Monteiro Pinto, Waltesia Perini, Gerson Fernando Mendes Pereira, Angélica Espinosa Miranda, and Mariângela Freitas da Silveira
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Soropositividade para HIV ,Papillomavírus humano ,Programas de rastreamento ,Neoplasias do colo do útero ,Serviços de saúde ,Medicine - Abstract
Introdução: Mulheres vivendo com HIV/AIDS possuem maior frequência de neoplasias anogenitais decorrentes da infecção pelo papilomavírus humano (HPV). A Organização Mundial da Saúde recomenda que o rastreio de câncer do colo do útero seja utilizado por testes moleculares que amplificam o material genético viral, como o HPV-DNA. Além da coleta por profissionais da saúde, a autocoleta de amostras vaginais consiste em uma ferramenta útil para ampliação do acesso à testagem. Objetivo: Descrever os resultados do estudo piloto que avaliou a aceitabilidade da autocoleta de amostra vaginal e aplicabilidade da oferta de testes HPV-DNA com autocoleta de amostras vaginais para mulheres vivendo com HIV/AIDS no Brasil. Métodos: Estudo transversal descritivo envolvendo mulheres vivendo com HIV/AIDS atendidas em oito serviços ambulatoriais distribuídos em todas as regiões do país no período de maio/2021 a maio/2022 e um laboratório central. Realizou-se a oferta de autocoleta vaginal e uma entrevista com as participantes sobre dados sociodemográficos e impressões da autocoleta. Resultados: No total, 1.919 mulheres vivendo com HIV/AIDS com média de 45 anos participaram do estudo. Houve detecção de algum tipo de HPV em 66% (1.267) dos casos. A maioria (71,9%) afirmou preferir a autocoleta à coleta de amostras por profissionais da saúde. Apenas 53,8% das participantes realizaram citologia na periodicidade adequada, conforme recomendação do protocolo. Conclusão: Os resultados poderão apoiar a implementação dos testes de biologia molecular para detecção de HPV em mulheres vivendo com HIV/AIDS, incluindo a possibilidade de autocoleta vaginal, promovendo a ampliação do acesso ao rastreamento de câncer do colo do útero. Palavras-chave: Soropositividade para HIV. Papillomavírus humano. Programas de rastreamento. Neoplasias do colo do útero. Serviços de saúde.
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- 2024
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10. Associations of lifestyle with burnout risk and recovery need in Flemish secondary schoolteachers: a cross-sectional study
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Yanni Verhavert, Tom Deliens, Jelle Van Cauwenberg, Elke Van Hoof, Christophe Matthys, Juriena de Vries, Peter Clarys, Kristine De Martelaer, and Evert Zinzen
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Medicine ,Science - Abstract
Abstract Teacher burnout and high recovery need are a topic of concern for educational institutions. This cross-sectional study assesses the association between lifestyle (including physical activity (PA), sedentary behavior (SB), dietary behavior and sleep), burnout risk and recovery need in 1878 secondary schoolteachers in Flanders. In September–October 2019, an online-questionnaire assessing burnout (i.e., emotional exhaustion, depersonalization, personal accomplishment), recovery need, PA-domains, SB-domains, dietary behavior (including fruit and vegetable intake and diet quality) and sleep during the week and the weekend was completed. Multiple linear regression models were applied. More emotional exhaustion was associated with more domestic and garden PA, work-related SB and sleep during the weekend, whereas higher scores of emotional exhaustion were associated with lower fruit intake, diet quality and less sleep during the week. More depersonalization was associated with more leisure-time PA and work-related SB and with lower fruit intake. Teachers showing more recovery need, showed more domestic and garden PA and work-related SB, but less leisure-time PA and sleep during the week. Future research should use longitudinal or experimental designs to get more insight into causality. Despite the low effect sizes, education networks and schools might benefit from promoting and facilitating a healthy lifestyle in secondary schoolteachers.
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- 2024
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11. Author Correction: Impact of Plasmodium vivax malaria on executive and cognitive functions in elderlies in the Brazilian Amazon
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Rockson C. Pessoa, Gabriela F. Oliveira-Pessoa, Brenda K. A. Souza, Vanderson S. Sampaio, André Luiz C. B. Pinto, Larissa L. Barboza, Gabriel S. Mouta, Emanuelle Lira Silva, Gisely C. Melo, Wuelton M. Monteiro, José H. Silva-Filho, Marcus V. G. Lacerda, and Djane Clarys Baía-da-Silva
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Medicine ,Science - Published
- 2024
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12. Short-term cutaneous vasodilatory and thermosensory effects of topical methyl salicylate
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Ninja Versteeg, Vanessa Wellauer, Selina Wittenwiler, Dirk Aerenhouts, Peter Clarys, and Ron Clijsen
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wintergreen oil ,blood flow ,counterirritation ,skin microcirculation ,muscle oxygen saturation ,skin temperature ,Physiology ,QP1-981 - Abstract
Introduction:Methyl salicylate, the main compound of wintergreen oil, is widely used in topical applications. However, its vascular and thermosensory effects are not fully understood. The primary aim was to investigate the effects of topical methyl salicylate on skin temperature (Tskin), skin microcirculation (MCskin) and muscle oxygen saturation (SmO2) compared to a placebo gel. The secondary aim was to assess thermosensory responses (thermal sensation, thermal comfort) and to explore to which extent these sensations correspond to the physiological responses over time.Methods:21 healthy women (22.2 ± 2.9 years) participated in this single-blind, randomized controlled trial. Custom-made natural wintergreen oil (12.9%), containing methyl salicylate (>99%) and a placebo gel, 1 g each, were applied simultaneously to two paravertebral skin areas (5 cm × 10 cm, Th4-Th7). Tskin (infrared thermal imaging), MCskin (laser speckle contrast imaging) and SmO2 (deep tissue oxygenation monitoring) and thermosensation (Likert scales) were assessed at baseline (BL) and at 5-min intervals during a 45 min post-application period (T0-T45).Results:Both gels caused an initial decrease in Tskin, with Tskin(min) at T5 for both methyl salicylate (BL-T5: Δ-3.36°C) and placebo (BL-T5: Δ-3.90°C), followed by a gradual increase (p < .001). Methyl salicylate gel resulted in significantly higher Tskin than placebo between T5 and T40 (p < .05). For methyl salicylate, MCskin increased, with MCskin(max) at T5 (BL-T5: Δ88.7%). For placebo, MCskin decreased (BL-T5: Δ-17.5%), with significantly lower values compared to methyl salicylate between T0 and T45 (p < .05). Both gels had minimal effects on SmO2, with no significant differences between methyl salicylate and placebo (p > .05). Thermal sensation responses to topical methyl salicylate ranged from “cool” to “hot”, with more intense sensations reported at T5.Discussion:The findings indicate that topical methyl salicylate induces short-term cutaneous vasodilation, but it may not enhance skeletal muscle blood flow. This study highlights the complex sensory responses to its application, which may be based on the short-term modulation of thermosensitive transient receptor potential channels.
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- 2024
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13. Data Descriptor of Snakebites in Brazil from 2007 to 2020
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Alexandre Vilhena Silva-Neto, Gabriel Santos Mouta, Antônio Alcirley Silva Balieiro, Jady Shayenne Mota Cordeiro, Patricia Carvalho Silva Balieiro, Tatyana Costa Amorin Ramos, Djane Clarys Baia-da-Silva, Élisson Silva Rocha, Patricia Takako Endo, Theo Lynn, Wuelton Marcelo Monteiro, and Vanderson Souza Sampaio
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snakebite envenomations ,information system ,Bibliography. Library science. Information resources - Abstract
Snakebite envenomations (SBE) are a significant global public health threat due to their morbidity and mortality. This is a neglected public health issue in many tropical and subtropical countries. Brazil is in the top ten countries affected by SBE, with 32,160 cases reported only in 2020, posing a high burden for this population. In this paper, we describe the data structure of snakebite records from 2007 to 2020 in the Notifiable Disease Information System (SINAN), made available by the Brazilian Ministry of Health (MoH). In addition, we also provide R scripts that allow a quick and automatic updating of data from the SINAN according to its availability. The data presented in this work are related to clinical and demographic information on SBE cases. Also, data on outcomes, laboratory results, and treatment are available. The dataset is available and freely accessible; however, preprocessing, adjustments, and standardization are necessary due to incompleteness and inconsistencies. Regardless of these limitations, it provides a solid basis for assessing different aspects and the national burden of envenoming.
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- 2024
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14. Correction: Establishing a Belgian Nutrition Society (BNS): Filling the Void
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Cani, Patrice, Clarys, Peter, Clinquart, Antoine, De Henauw, Stefaan, Delzenne, Nathalie, Deriemaeker, Peter, Douny, Caroline, Guelinckx, Isabelle, Huybrechts, Inge, Huybregts, Lieven, Kolsteren, Patrick, Lachat, Carl, Laquiere, Isabelle, Larondelle, Yvan, Leroy, Jef, Manghuin-Rogister, Guy, Matthys, Christophe, Mullie, Patrick, Neve, Jean, Scippo, Marie-Louise, Sioen, Isabelle, Remaut, Anne-Marie, Van Camp, John, Vandevijvere, Stefanie, and Vansant, Margareta
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- 2023
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15. Author Correction: Associations of lifestyle with burnout risk and recovery need in Flemish secondary schoolteachers: a cross-sectional study
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Yanni Verhavert, Tom Deliens, Jelle Van Cauwenberg, Elke Van Hoof, Christophe Matthys, Juriena de Vries, Peter Clarys, Kristine De Martelaer, and Evert Zinzen
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Medicine ,Science - Published
- 2024
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16. Impaired Carbohydrate Metabolism among Women with Chronic Low Back Pain and the Role of Dietary Carbohydrates: A Randomized Controlled Cross-Over Experiment
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Ömer Elma, Sevilay Tümkaya Yılmaz, Jo Nijs, Peter Clarys, Iris Coppieters, Evelien Mertens, Anneleen Malfliet, and Tom Deliens
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chronic pain ,low back pain ,pain sensitivity ,postprandial glycemic response ,carbohydrate intake ,glycemic index ,Medicine - Abstract
Background: Impaired glucose regulation is suggested to be related to chronic low back pain (CLBP), although it is not clear how they interact with each other. Thus, the primary aim of this study was to investigate differences in postprandial glycemic responses (PPGRs) (the first sign of impaired glucose metabolism) to high- (sucrose) and low-glycemic index (GI) (isomaltulose) beverages in normoglycemic women with CLBP and healthy controls (HCs) and explore whether any group that showed greater PPGRs to high-GI beverage intake would benefit when the high-GI beverage was replaced with a low-GI beverage. Secondly, this study aimed to explore the association between PPGR and pain in patients with CLBP. Methods: This study was registered at clinicaltrials.org (NCT04459104) before the start of the study. In this study, 53 CLBP patients and 53 HCs were recruited. After 11–12 h of fasting, each participant randomly received isomaltulose or sucrose. Blood glucose levels were measured during the fasting state and 15, 30, 45, 60, 90, and 120 min after the beverage intake, and each participant underwent experimental pain measures. Results: Compared to the HCs, the CLBP group showed significantly higher PPGRs to sucrose (p < 0.021). Additionally, the CLBP group showed a significantly higher decrease in PPGR (p = 0.045) when comparing PPGR to sucrose with PPGR to isomaltulose. Correlation analysis revealed a positive association between self-reported pain sensitivity and PPGR to sucrose, while there was no association found between any experimental pain measures and glycemic responses. Conclusions: Overall, these findings suggest that normoglycemic CLBP patients might have a higher risk of developing impaired glucose tolerance than the HCs and might benefit more when high-GI foods are replaced with low-GI ones.
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- 2024
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17. Effects of combined physical and cognitive program performed in socially enriched environment on older people’s cognitive abilities and quality of life (StimCoAPS): study protocol for a randomized controlled trial
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David Clarys, Veronique David, Virginie Migeot, Tiphanie Gonnord, Olivier Dupuy, Marion Albouy, Rebeca Grangeiro, Catherine Esnard, Geoffroy Boucard, Pierre Faivre, Soleane Vielotte, Maxime Pilon, Linda Boureau, Nicolas Troubat, Thomas Faugeroux, Paulin Lacombe, Thomas Chassin, Thomas Abascal, and Camille Revel
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Medicine (General) ,R5-920 - Abstract
The number of older people worldwide is constantly increasing. However, ageing is accompanied by a decline in cognitive ability that can affect quality of life. Cognitive, physical and social activities can all slow this decline but social factors and their contribution to the well-being remain under-researched. The aim of this study is to analyse how the practice environment can foster these social relations and thus enhance well-being and to identify the psychological dimensions that are activated by social relations. This study is a 3-year randomised controlled trial designed to assess the effects on participants’ cognitive abilities and quality of life of a combined (ie, physical and cognitive) training programme in different social practice environments. A total of 159 older people (≥65 years old) will be recruited and randomly assigned to one of three practice environments: individual practice at home (n=53), group practice in a gymnasium (n=53) and group practice in an enriched environment (n=53). All participants will complete 12-week combined training sessions and will be assessed four times: before the start, in the middle, at the end and 6 months after the end of the programme. They will undergo cognitive function (episodic memory and executive functions), physical capacity (aerobic fitness, muscle strength and dynamic balance) and psychosocial assessments (indicators of psychological well-being, social support, self-esteem, anxiety, depression and achievement goal strategies), as well as semistructured interviews. Statistical analyses will be conducted to assess the effect of the practice environment on the perceived benefits of this programme in terms of cognitive abilities and quality of life, and to determine the role of psychosocial factors in this relationship.This protocol has been approved by an institutional review board (CERSTAPS: IRB00012476-2022-20-01-146). Trials registration number: NCT05721508.
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- 2023
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18. Detection of HPV DNA in vaginal samples self-collected by women living with HIV treated through the Brazilian public health system: Prevalence and analysis of risk factors
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Mariângela Freitas da Silveira, Romina Buffarini, Pâmela Cristina Gaspar, Hanalydia de Melo Machado, Maria Luiza Bazzo, Aline Scherer, Álvaro Luis Colusso, Ana Gabriela Álvares Travassos, Denise Arakaki-Sanchez, Djane Clarys Baia-da-Silva, Eduardo Campos de Oliveira, Isabella Ribeiro Zago, Marcos de Assis Moura, Marcus Vinicius Guimarães de Lacerda, Simone Murta Martins, Tânia Reuter, Valdir Monteiro Pinto, Waltesia Perini, Gerson Fernando Mendes Pereira, and Angélica Espinosa Miranda
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HPV ,Screening ,HIV ,Uterine cervical neoplasms ,Cervical intraepithelial neoplasia ,HPV-DNA ,Arctic medicine. Tropical medicine ,RC955-962 - Abstract
ABSTRACT Background: Women living with human immunodeficiency virus (HIV) (WLWH) are more likely to be infected with the oncogenic human papillomavirus (HPV). We assessed the prevalence of high-risk (HR) (16/18/31/33/35/39/45/51/52/56/58/59/68/73/82), probable high-risk (pHR) (26/53/66), and low-risk (LR) (6/11/40/42/43/44/54/61/70) HPV types and their associated risk factors. Methods: This cross-sectional study of WLWH aged 18-64 years included one laboratory and eight HIV-specialty healthcare facilities in the pilot network. Descriptive statistics were used to assess sociodemographic and behavioral characteristics. Adjusted analyses were conducted to evaluate risk factors associated with HR and/or pHR HPV infection in WLWH. Results: From May/2021 to May/2022, 1,914 (92.5%) WLWH participated in the pilot study and had valid HPV-DNA results of self-collected vaginal samples. The median age of the participants was 45 years, 60.1% had ≥ 9 years of schooling, 80.5% were ≤ 18 years at first sexual intercourse, and 51.7% had > 4 sexual partners throughout life. The prevalence of any HPV type, HR HPV, pHR HPV, and LR HPV was 65.8%, 49.6%, 16.7%, and 40.0%, respectively. Age was inversely associated with pHR and/or HR-HPV (p < 0.001), and education level was inversely associated with HR-HPV (p = 0.003) types. Any HR or pHR was associated with being single (p = 0.029) and exchanging sex for drugs (p = 0.037). Conclusions: The prevalence of HPV, especially HR HPV, among WLWH is high in Brazil, highlighting the need for HPV screening in this population. Self-collection of vaginal samples is an important strategy for increasing testing access.
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- 2023
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19. Environmental factors influencing older adults’ walking for transportation: a study using walk-along interviews
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Van Cauwenberg Jelle, Van Holle Veerle, Simons Dorien, Deridder Riet, Clarys Peter, Goubert Liesbet, Nasar Jack, Salmon Jo, De Bourdeaudhuij Ilse, and Deforche Benedicte
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Physical environment ,Physical activity ,Walking for transportation ,Older adults ,Qualitative study ,Walk-along interviews ,Nutritional diseases. Deficiency diseases ,RC620-627 ,Public aspects of medicine ,RA1-1270 - Abstract
Abstract Background Current knowledge on the relationship between the physical environment and walking for transportation among older adults (≥ 65 years) is limited. Qualitative research can provide valuable information and inform further research. However, qualitative studies are scarce and fail to include neighborhood outings necessary to study participants’ experiences and perceptions while interacting with and interpreting the local social and physical environment. The current study sought to uncover the perceived environmental influences on Flemish older adults’ walking for transportation. To get detailed and context-sensitive environmental information, it used walk-along interviews. Methods Purposeful convenience sampling was used to recruit 57 older adults residing in urban or semi-urban areas. Walk-along interviews to and from a destination (e.g. a shop) located within a 15 minutes’ walk from the participants’ home were conducted. Content analysis was performed using NVivo 9 software (QSR International). An inductive approach was used to derive categories and subcategories from the data. Results Data were categorized in the following categories and subcategories: access to facilities (shops & services, public transit, connectivity), walking facilities (sidewalk quality, crossings, legibility, benches), traffic safety (busy traffic, behavior of other road users), familiarity, safety from crime (physical factors, other persons), social contacts, aesthetics (buildings, natural elements, noise & smell, openness, decay) and weather. Conclusions The findings indicate that to promote walking for transportation a neighborhood should provide good access to shops and services, well-maintained walking facilities, aesthetically appealing places, streets with little traffic and places for social interaction. In addition, the neighborhood environment should evoke feelings of familiarity and safety from crime. Future quantitative studies should investigate if (changes in) these environmental factors relate to (changes in) older adults’ walking for transportation.
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- 2012
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20. Physical environmental factors related to walking and cycling in older adults: the Belgian aging studies
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Van Cauwenberg Jelle, Clarys Peter, De Bourdeaudhuij Ilse, Van Holle Veerle, Verté Dominique, De Witte Nico, De Donder Liesbeth, Buffel Tine, Dury Sarah, and Deforche Benedicte
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Public aspects of medicine ,RA1-1270 - Abstract
Abstract Background Socio-ecological models emphasize the relationship between the physical environment and physical activity (PA). However, knowledge about this relationship in older adults is limited. Therefore, the present study aims to investigate the relationship between area of residence (urban, semi-urban or rural) and older adults' walking and cycling for transportation and recreation. Additionally, relationships between several physical environmental factors and walking and cycling and possible moderating effects of area of residence, age and gender were studied. Methods Data from 48,879 Flemish older adults collected in 2004-2010 through peer research were analyzed. Walking, cycling and environmental perceptions were assessed using self-administered questionnaires. The Study Service of the Flemish Government provided objective data on municipal characteristics. Multilevel logistic regression analyses were applied. Results Urban participants were more likely to walk daily for transportation compared to rural (OR = 1.43; 95% CI = 1.22, 1.67) and semi-urban participants (OR = 1.32; 95% CI = 1.13, 1.54). Urban participants were less likely to cycle daily for transportation compared to semi-urban participants (OR = 0.72; 95% CI = 0.56, 0.92). Area of residence was unrelated to weekly recreational walking/cycling. Perceived short distances to services (ORs ranging from 1.04 to 1.19) and satisfaction with public transport (ORs ranging from 1.07 to 1.13) were significantly positively related to all walking/cycling behaviors. Feelings of unsafety was negatively related to walking for transportation (OR = 0.93, 95% CI = 0.91, 0.95) and recreational walking/cycling (OR = 0.95, 95% CI = 0.92, 0.97). In females, it was also negatively related to cycling for transportation (OR = 0.94, 95% CI = 0.90, 0.98). Conclusions Urban residents were more likely to walk for transportation daily compared to semi-urban and rural residents. Daily cycling for transportation was less prevalent among urban compared to semi-urban residents. Access to destinations appeared to be important for promoting both walking and cycling for transportation and recreation across all demographic subgroups. Additionaly, feelings of unsafety were associated with lower rates of walking for transportation and walking/cycling for recreation in all subgroups and cycling for transportation in females. No clear patterns emerged for other environmental factors.
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- 2012
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21. Health aspects, nutrition and physical characteristics in matched samples of institutionalized vegetarian and non-vegetarian elderly (> 65yrs)
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Hebbelinck Marcel, De Ridder Dolf, Aerenhouts Dirk, Deriemaeker Peter, and Clarys Peter
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Nutrition. Foods and food supply ,TX341-641 ,Nutritional diseases. Deficiency diseases ,RC620-627 - Abstract
Abstract Background Epidemiological studies indicate that a well balanced vegetarian diet offers several health benefits including a lower prevalence of prosperity diseases in vegetarians compared to omnivores. It was the purpose of the present study to compare nutritional and physical characteristics in matched samples of institutionalized vegetarian (V) and non-vegetarian (NV) elderly. Methods Twenty-two female and 7 male V (females: 84.1 ± 5.1yrs, males: 80.5 ± 7.5yrs) and 23 female and 7 male NV (females: 84.3 ± 5.0yrs, males: 80.6 ± 7.3yrs) participated. All subjects were over 65 years of age, and free of major disease or physical handicap. Dietary intake, blood profile, anthropometrics, and handgrip strength were determined. Results Mean daily energy intake was 6.8 ± 2.0MJ in V females, and 8.0 ± 1.4MJ in the NV females, only the V did not reach the recommended value of 7.8 MJ. Male V and NV had a mean daily energy intake of 8.7 ± 1.6MJ and 8.7 ± 1.2MJ respectively (RDI: 8.8 MJ). Mean carbohydrate intake was significantly below the RDI in NV only (female V: 47.8 ± 7.5E%, female NV: 43.3 ± 4.6E%, male V: 48.1 ± 6.4E%, male NV: 42.3 ± 3.6E%), while protein (female V: 17.3 ± 3.4E%, female NV: 19.5 ± 3.5E%, male V: 17.8 ± 3.4E%, male NV: 21.0 ± 2.0E%), and saturated fat intake (female V: 25.4 ± 8.2 g/day, female NV: 32.2 ± 6.9 g/day, male V: 31.4 ± 12.9 g/day, male NV: 33.4 ± 4.7 g/day) were too high in both V and NV. Mean micronutrient intakes met the RDI's in all 4 groups. Mean blood concentrations for vitamin B12, folic acid, iron, and calcium were normal in all 4 groups. Mean zinc blood serum was below the reference value in all groups, whereas estimated zinc intake was in agreement with the RDI. The mean blood cholesterol concentration was above the 200 mg/dl upper limit in the V group (213 ± 40 mg/dl) and below that limit in the NV (188 ± 33 mg/dl) group. Mean BMI was 26.1 ± 4.7 kg/m2 in the female V, 26.8 ± 3.7 kg/m2 in the female NV, 23.5 ± 3.7 kg/m2 in the male V, and 25.2 ± 4.2 kg/m2 in the male NV. V and NV scored below the reference values for the handgrip strength test. Conclusions Generally, our results show a similar profile for V and NV concerning dietary intake, blood values, and physical characteristics. Attention should be paid to the intake of mono- and disaccharides and saturated fats in the diet of both V and NV. This study indicates that a vegetarian lifestyle has no negative impact on the health status at older age.
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- 2011
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22. Positive impact of social relationships fostered by physical and/or cognitive group activity on older people’s quality of life: PRISMA systematic review
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Tiphanie Gonnord, David Clarys, Geoffroy Boucard, and Catherine Esnard
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social relations ,quality of life ,physical activities ,cognitive activities ,wellbeing ,aging ,Psychology ,BF1-990 - Abstract
IntroductionThis review identified and examined the research literature on the effect of participating in physical and/or cognitive activities on older people’s quality of life, to establish whether the social relationships fostered by these activities can be a vector of better physical, mental and social quality of life.MethodA systematic review of the literature was conducted according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines. We searched four databases (MEDLINE, APA PsycArticles/PsycInfo, PubMed, and Web of Science) for articles published between 1975 and 2022 using search terms related to psychosocial, population, and intervention topics. Studies were eligible if they involved older adults, participation in at least one activity (physical or cognitive), and at least one quality of life related outcome measure.ResultsWe selected 20 articles published between 1990 and 2021, the majority concerning studies conducted in English-speaking countries. Ten studies were interventional (introduction of program of activities), and 10 studies were observational (60% quantitative, 40% qualitative). Overall, results revealed a positive impact of the activities on every aspect of quality of life (i.e., cognitive, physical, social, psychological, and quality of life in general).ConclusionThe present review confirmed the beneficial impact of practicing physical and/or cognitive group activities on older people’s quality of life, but the contribution of social factors and social relationships remains underestimated and not well defined in researches.
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- 2023
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23. What are the economic dimensions of occupational health and how should they be measured? A qualitative study
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Nathanael Lutz, Lena Dalle Grave, Dirk Richter, Tom Deliens, Nick Verhaeghe, Jan Taeymans, and Peter Clarys
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Occupational health ,Cost-Benefit analysis ,Costs and cost analysis ,Indirect costs ,Organizational efficiency ,Intangible benefits ,Public aspects of medicine ,RA1-1270 - Abstract
Abstract Background Decision makers want to know if there is a financial benefit in investing scarce resources in occupational health management (OHM). Economic evaluations (EEs) of OHM-strategies try to answer this question. However, EEs of OHM-strategies which are strongly marked by quantitative methods may be limited by contextual, qualitative residuals. Therefore, the objectives of this study were to (1) explore important economic dimensions of OHM and (2) to discuss the methods used in current EEs for measuring these dimensions. Methods In this explorative qualitative study, OHM-specialists were recruited via the Swiss organisation for health promotion. Thirteen semi-structured interviews were performed from November 2020 until May 2021. Videotapes were transcribed verbatim and organised by using an open coding strategy. Codes were clustered and synthesised as themes (i.e. the dimensions of EEs of OHM) through a mix of inductive and deductive content analysis. Member check with eight participants was accomplished to validate the results. Results The interviews had an average duration of 70.5 min and yielded 609 individual codes. These codes were merged into 28 subcategories which were finally categorised into five main themes: Understanding of OHM, costs, benefits, environmental aspects, and evaluation of OHM. Participants stated that the greater part of costs and benefits cannot be quantified or monetised and thus, considered in quantitative EEs. For example, they see a culture of health as key component for a successful OHM-strategy. However, the costs to establish such a culture as well as its benefits are hard to quantify. Participants were highly critical of the use of absenteeism as a linear measure of productivity. Furthermore, they explained that single, rare events, such as a change in leadership, can have significant impact on employee health. However, such external influence factors are difficult to control. Conclusions Participants perceived costs and benefits of OHM significantly different than how they are represented in current EEs. According to the OHM-specialists, most benefits cannot be quantified and thus, monetised. These intangible benefits as well as critical influencing factors during the process should be assessed qualitatively and considered in EEs when using them as a legitimation basis vis-à-vis decision makers.
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- 2022
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24. Dietary intake, physical activity and sedentary behavior and association with BMI during the transition to parenthood: a prospective dyadic study
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Vickà Versele, Lara Stas, Dirk Aerenhouts, Tom Deliens, Christophe Matthys, Leonardo Gucciardo, Roland Devlieger, Peter Clarys, and Annick Bogaerts
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body mass index ,nutrition ,physical activity ,sedentary behavior ,pregnancy ,postpartum ,Public aspects of medicine ,RA1-1270 - Abstract
IntroductionLittle is known on how diet, physical activity (PA) and sedentary behavior (SB) changes during pregnancy and after childbirth in primiparous couples. Moreover, it is unclear how potential behavioral changes are associated with changes in BMI. This study examined changes in diet, PA and SB, and their association with changes in BMI in couples transitioning to parenthood.MethodsDietary intake (FFQ), PA, SB (both Actigraph GT3X accelerometers) and BMI of women and men were assessed at 12 weeks of gestation, 6 weeks and 6 months postpartum. Data were analyzed using dyadic longitudinal data analyses techniques.ResultsIn women, a decrease in fruit intake, an increase in alcohol intake, an increase of light-intensity PA, and a decrease in SB were observed from the beginning of pregnancy up to 6 months postpartum. Decreases in fruit intake between 6 weeks and 6 months postpartum was associated with increases in BMI. Men did not show significant dietary changes, while an increase in light-intensity PA and a decrease in moderate-to-vigorous PA (MVPA) was observed at 6 months postpartum when compared to 12 weeks of gestation. Paternal increases in “avoidance food group” intake were associated with increases in BMI between baseline and 6 weeks postpartum. No associations of changes in BMI and changes in PA and SB were found.DiscussionNot only mothers but also fathers experienced unfavorable changes in lifestyle during the transition to parenthood, with impact on BMI changes. This highlights the need to monitor unhealthy changes in lifestyle and body weight in both parents when expecting a child and after childbirth.Clinical trial registrationClinicaltrials.gov, NCT03454958.
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- 2023
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25. Acceptability of short message service (SMS) as a tool for malaria treatment adherence in the Brazilian Amazon: a qualitative study
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Sheila Rodovalho, Ádila Liliane Barros Dias, Maria Paz Ade, Diego Macias Saint-Gerons, Jose Luis Castro, Andrea Beratarrechea, Felipe Leão Gomes Murta, Alicia Cacau Patrine dos Santos, Leonardo Lincoln Gomes Marques, Vanderson Souza Sampaio, Djane Clarys Baia-da-Silva, and Wuelton Marcelo Monteiro
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Malaria ,SMS ,Medication adherence ,Malaria treatment ,Arctic medicine. Tropical medicine ,RC955-962 - Abstract
ABSTRACT Background: Malaria is one of the leading causes of morbidity worldwide, and patient adherence to prescribed antimalarials is essential for effective treatment. Methods: This cross-sectional study, with in-depth telephone interviews, analyzed participants’ perceptions of short message service (SMS) in adherence to treatment. Results: Five thematic categories emerged: decreased forgetfulness, the novelty of the tool, easy-to-understand language, the impact of SMS messages during treatment, and suggestions for improvement and complaints. Conclusions: SMS could assist patients in adhering to prescribed antimalarials.
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- 2023
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26. The activity of methylene blue against asexual and sexual stages of Plasmodium vivax
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Camila Fabbri, Glenda Quaresma Ramos, Djane Clarys Baia-da-Silva, Alexandre Oliveira Trindade, Luis Carlos Salazar-Alvarez, Juliana Costa Ferreira Neves, Ivanildes dos Santos Bastos, Allyson Guimarães Costa, Marcus Vinicius Guimarães Lacerda, Wuelton Marcelo Monteiro, Fabio Trindade Maranhão Costa, and Stefanie Costa Pinto Lopes
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gametocyte ,ookinete ,malaria ,transmission-blocking ,antimalarial drug ,Microbiology ,QR1-502 - Abstract
Methylene blue (MB) is an alternative for combating drug-resistant malaria parasites. Its transmission-blocking potential has been demonstrated in vivo in murine models, in vitro, and in clinical trials. MB shows high efficacy against Plasmodium vivax asexual stages; however, its efficacy in sexual stages is unknown. In this study, we evaluated the potential of MB against asexual and sexual forms of P. vivax isolated from the blood of patients residing in the Brazilian Amazon. An ex vivo schizont maturation assay, zygote to ookinete transformation assay, direct membrane feed assay (DMFA), and standard membrane feed assay (SMFA) using P. vivax gametocytes with MB exposure were performed. A cytotoxicity assay was also performed on freshly collected peripheral blood mononuclear cells (PBMCs) and the hepatocyte carcinoma cell line HepG2. MB inhibited the P. vivax schizont maturation and demonstrated an IC50 lower than that of chloroquine (control drug). In the sexual forms, the MB demonstrated a high level of inhibition in the transformation of the zygotes into ookinetes. In the DMFA, MB did not considerably affect the infection rate and showed low inhibition, but it demonstrated a slight decrease in the infection intensity in all tested concentrations. In contrast, in the SMFA, MB was able to completely block the transmission at the highest concentration (20 µM). MB demonstrated low cytotoxicity to fresh PBMCs but demonstrated higher cytotoxicity to the hepatocyte carcinoma cell line HepG2. These results show that MB may be a potential drug for vivax malaria treatment.
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- 2023
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27. Clinical and Acoustic Alterations of Swallowing in Children Exposed to Zika Virus during Pregnancy in a Cohort in Amazonas, Brazil: A Case Series Study
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Cristina de Souza Rodrigues, Raillon Keven Santos Souza, Cosmo Vieira Rocha Neto, Rodrigo Haruo Otani, Daniel de Medeiros Batista, Ana Karla Nelson de Oliveira Maia, Kleber Pinheiro de Oliveira Filho, Thais Dourado de Andrade, Emmilyn de Andrade Almeida, Luiz Henrique Gonçalves Maciel, Lucíola de Fátima Albuquerque Almeida Peixoto Castro, Marília Rosa Abtibol-Bernardino, Djane Clarys Baia-da-Silva, Silvana Gomes Benzecry, Marcia da Costa Castilho, Flor Ernestina Martínez-Espinosa, Maria das Graças Costa Alecrim, Rosane Sampaio Santos, and Camila Botto-Menezes
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Zika virus ,arbovirus ,congenital Zika virus syndrome ,oropharyngeal dysphagia ,non-microcephalic children ,Microbiology ,QR1-502 - Abstract
Oropharyngeal dysphagia (OD) is a swallowing disorder that involves difficulty in safely passing the food bolus from the oral cavity to the stomach. OD is a common problem in children with congenital Zika virus syndrome (CZS). In this case series, we describe the clinical and acoustic alterations of swallowing in children exposed to the Zika virus during pregnancy in a cohort from Amazonas, Brazil. From July 2019 to January 2020, 22 children were evaluated, 6 with microcephaly and 16 without microcephaly. The mean age among the participants was 35 months (±4.6 months). All children with microcephaly had alterations in oral motricity, mainly in the lips and cheeks. Other alterations were in vocal quality, hard palate, and soft palate. Half of the children with microcephaly showed changes in cervical auscultation during breast milk swallowing. In children without microcephaly, the most frequently observed alteration was in lip motricity, but alterations in auscultation during the swallowing of breast milk were not observed. Regarding swallowing food of a liquid and pasty consistency, the most frequent alterations were incomplete verbal closure, increased oral transit time, inadequacy in capturing the spoon, anterior labial leakage, and increased oral transit time. Although these events are more frequent in microcephalic children, they can also be seen in non-microcephalic children, which points to the need for an indistinct evaluation of children exposed in utero to ZIKV.
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- 2023
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28. Does the Presence or a High Titer of Yellow Fever Virus Antibodies Interfere with Pregnancy Outcomes in Women with Zika Virus Infection?
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Isa Cristina Ribeiro Piauilino, Raillon Keven dos Santos Souza, Maurício Teixeira Lima, Yanka Karolinna Batista Rodrigues, Luís Felipe Alho da Silva, Ayrton Sena Gouveia, Alexandre Vilhena da Silva Neto, Bárbara Aparecida Chaves, Maria das Graças Costa Alecrim, Camila Helena Aguiar Bôtto de Menezes, Márcia da Costa Castilho, Djane Clarys Baia-da-Silva, and Flor Ernestina Martinez Espinosa
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Zika virus ,arbovirus ,congenital Zika virus syndrome ,yellow fever virus ,yellow fever virus vaccine ,non-microcephalic children ,Microbiology ,QR1-502 - Abstract
Zika virus (ZIKV) and yellow fever virus (YFV) originated in Africa and expanded to the Americas, where both are co-circulated. It is hypothesized that in areas of high circulation and vaccination coverage against YFV, children of pregnant women have a lower risk of microcephaly. We evaluated the presence and titers of antibodies and outcomes in women who had ZIKV infection during pregnancy. Pregnancy outcomes were classified as severe, moderate, and without any important outcome. An outcome was defined as severe if miscarriage, stillbirth, or microcephaly occurred, and moderate if low birth weight and/or preterm delivery occurred. If none of these events were identified, the pregnancy was defined as having no adverse effects. A sample of 172 pregnant women with an acute ZIKV infection confirmed during pregnancy were collected throughout 2016. About 89% (150 of 169) of them presented immunity against YFV, including 100% (09 of 09) of those who had severe outcomes, 84% (16 of 19) of those who had moderate outcomes, and 89% (125 of 141) of those who had non-outcomes. There was no difference between groups regarding the presence of anti-YFV antibodies (p = 0.65) and YFV titers (p = 0.6). We were unable to demonstrate a protective association between the presence or titers of YFV antibodies and protection against serious adverse outcomes from exposure to ZIKV in utero.
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- 2023
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29. Impact of Plasmodium vivax malaria on executive and cognitive functions in elderlies in the Brazilian Amazon
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Rockson C. Pessoa, Gabriela F. Oliveira-Pessoa, Brenda K. A. Souza, Vanderson S. Sampaio, André Luiz C. B. Pinto, Larissa L. Barboza, Gabriel S. Mouta, Emanuelle Lira Silva, Gisely C. Melo, Wuelton M. Monteiro, José H. Silva-Filho, Marcus V. G. Lacerda, and Djane Clarys Baía-da-Silva
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Medicine ,Science - Abstract
Abstract The exact path leading to cognitive impairment that goes beyond malaria is unclear, but it appears to be the result of interactive factors. Time of exposure to disease and recurrences are potentially major determinant variables. Cognitive impairment is described mainly in children, rarely in adults. The disease in high endemic areas usually does not affect elderlies, because of acquired immunity over time. However, this population is relatively more frequently sick in lower endemic areas, such as in the Amazon. This study assessed the effect of Plasmodium vivax malaria on the executive and cognitive functions of elderlies, in the Brazilian Amazon. A cohort study was conducted to evaluate executive and cognitive functions one week (T0), two months (T2) and eight months (T8) after the malaria episode. Mini-Mental State Examination (MMSE), Beck Depression Inventory II (BDI-II), Clock Drawing Test (CDT), Wechsler adult intelligence scale (WAIS-III), and Wisconsin Card Sorting Test (WCST) were used to assess executive and cognitive functions. One hundred-forty elderlies were enrolled (70 with P. vivax malaria and 70 without malaria). P. vivax malaria was associated with impairment of the executive and cognitive functions in elderlies for up to 8 months after acute P. vivax malaria. Prior history of malaria, recurrences and higher parasitemia were independently associated with various surrogates of executive and cognitive impairment. With the increase in life expectancy, elderlies living in malaria endemic areas will deserve more attention from health authorities, to guarantee improvement of their quality of life in the tropics.
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- 2022
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30. Rosette formation by Plasmodium vivax gametocytes favors the infection in Anopheles aquasalis
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Luis Carlos Salazar Alvarez, Vanessa Carneiro Barbosa, Omaira Vera Lizcano, Djane Clarys Baia da Silva, Rosa Amélia Gonçalves Santana, Camila Fabbri, Paulo Filemon Paoluci Pimenta, Wuelton Marcelo Monteiro, Letusa Albrecht, Marcus Vinicius Guimarães de Lacerda, Fabio Trindade Maranhão Costa, and Stefanie Costa Pinto Lopes
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malaria ,gametocyte ,rosetting ,cytoadhesion ,Plasmodium vivax ,vector ,Microbiology ,QR1-502 - Abstract
Plasmodium vivax is a public health problem and the most common type of malaria outside sub-Saharan Africa. The capacity of cytoadhesion, rosetting, and liver latent phase development could impact treatment and disease control. Although the ability to P. vivax gametocyte develop rosetting is known, it is not yet clear which role it plays during the infection and transmission process to the mosquito. Here, we used ex vivo approaches for evaluate the rosetting P. vivax gametocytes capacity and we have investigated the effect of this adhesive phenotype on the infection process in the vector Anopheles aquasalis mosquito. Rosette assays were performed in 107 isolates, and we have observed an elevated frequency of cytoadhesive phenomena (77,6%). The isolates with more than 10% of rosettes have presented a higher infection rate in Anopheles aquasalis (p=0.0252). Moreover, we found a positive correlation between the frequency of parasites in rosetting with the infection rate (p=0.0017) and intensity (p=0.0387) in the mosquito. The disruption of P. vivax rosette formation through mechanical rupture assay confirmed the previously findings, since the paired comparison showed that isolates with disrupted rosettes have a lower infection rate (p
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- 2023
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31. Plant-based dietary patterns in Flemish adults: a 10-year trend analysis
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Deliens, Tom, Mullie, Patrick, and Clarys, Peter
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- 2022
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32. What are the economic dimensions of occupational health and how should they be measured? A qualitative study
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Lutz, Nathanael, Dalle Grave, Lena, Richter, Dirk, Deliens, Tom, Verhaeghe, Nick, Taeymans, Jan, and Clarys, Peter
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- 2022
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33. Kidney function and daily emtricitabine/tenofovir disoproxil fumarate pre-exposure prophylaxis against HIV: results from the real-life multicentric demonstrative project PrEP Brazil
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Petruccelli, Karla Cristina Silva, Baía-da-Silva, Djane Clarys, Val, Fernando, Valões, Monica Santos, Cubas-Vega, Nadia, Silva-Neto, Alexandre Vilhena, Sampaio, Vanderson, Alencar, Aline, Pecoits-Filho, Roberto, Moreira, Rodrigo Carvalho, Cardoso, Sandra Wagner, Moreira, Ronaldo I., Leite, Iuri Costa, Madruga, José Valdez, Kallas, Esper G., Alencastro, Paulo R., Hoagland, Brenda, Grinsztejn, Beatriz, Santos, Valdiléa Gonçalves Veloso, and Lacerda, Marcus Vinícius Guimarães
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- 2022
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34. Impact of Plasmodium vivax malaria on executive and cognitive functions in elderlies in the Brazilian Amazon
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Pessoa, Rockson C., Oliveira-Pessoa, Gabriela F., Souza, Brenda K. A., Sampaio, Vanderson S., Pinto, André Luiz C. B., Barboza, Larissa L., Mouta, Gabriel S., Silva, Emanuelle Lira, Melo, Gisely C., Monteiro, Wuelton M., Silva-Filho, José H., Lacerda, Marcus V. G., and Baía-da-Silva, Djane Clarys
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- 2022
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35. HIV infection increases the risk of acquiring Plasmodium vivax malaria: a 4-year cohort study in the Brazilian Amazon HIV and risk of vivax malaria
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Guerra, Cecilia Victoria Caraballo, da Silva, Bernardo Maia, Müller, Pia, Baia-da-Silva, Djane Clarys, Moura, Marco Antônio Saboia, Araújo, José Deney Alves, Silva, Juan Carlo Santos e, Silva-Neto, Alexandre Vilhena, da Silva Balieiro, Antonio Alcirley, da Costa-Martins, André Guilherme, Melo, Gisely Cardoso, Val, Fernando, Bassat, Quique, Nakaya, Helder I., Martinez-Espinosa, Flor Ernestina, Lacerda, Marcus, Sampaio, Vanderson Souza, and Monteiro, Wuelton
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- 2022
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36. Pregnancy outcomes after snakebite envenomations: A retrospective cohort in the Brazilian Amazonia.
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Thaís P Nascimento, Alexandre Vilhena Silva-Neto, Djane Clarys Baia-da-Silva, Patrícia Carvalho da Silva Balieiro, Antônio Alcirley da Silva Baleiro, Jacqueline Sachett, Lisele Brasileiro, Marco A Sartim, Flor Ernestina Martinez-Espinosa, Fan Hui Wen, Manuela B Pucca, Charles J Gerardo, Vanderson S Sampaio, Priscila Ferreira de Aquino, and Wuelton M Monteiro
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Arctic medicine. Tropical medicine ,RC955-962 ,Public aspects of medicine ,RA1-1270 - Abstract
Snakebite envenomations (SBEs) in pregnant women can result in adverse maternal or neonatal effects, such as abortion, placental abruption, preterm labor, fetal malformations, and maternal, fetal or neonatal deaths. Despite the high incidence of SBEs in the Brazilian Amazon, there is no literature on the impact of SBEs on pregnancy outcomes. The objective of this study was to describe clinical epidemiology and outcomes associated with SBEs in women of childbearing age and pregnant women in the state of Amazonas, Western Brazilian Amazon, from 2007 to 2021. Information on the population was obtained from the Reporting Information System (SINAN), Mortality Information System (SIM) and Live Birth Information System (SINASC) for the period from 2007 to 2021. A total of 36,786 SBEs were reported, of which 3,297 (9%) involved women of childbearing age, and 274 (8.3%) involved pregnant women. Severity (7.9% in pregnant versus 8.7% in non-pregnant women) (P = 0.87) and case-fatality (0.4% in pregnant versus 0.3% in non-pregnant women) rates were similar between groups (P = 0.76). Pregnant women who suffered snakebites were at higher risk for fetal death (OR: 2.17, 95%CI: 1.74-2.67) and neonatal death (OR = 2.79, 95%CI: 2.26-3.40). This study had major limitations related to the completeness of the information on the pregnancy outcomes. Although SBE incidence in pregnant women is low in the Brazilian Amazon, SBEs increased the risk of fetal and neonatal deaths.
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- 2022
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37. Prevalence of glucose 6-phosphate dehydrogenase deficiency in highly malaria-endemic municipalities in the Brazilian Amazon: A region-wide screening study
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Joabi Rocha Nascimento, Jose Diego Brito-Sousa, Anne Cristine Gomes Almeida, Marly M Melo, Monica Regina Farias Costa, Laila Rowena Albuquerque Barbosa, Reinaldo Nery Ramos, Alexandre Vilhena Silva-Neto, Patricia Carvalho da Silva Balieiro, Erick Frota Gomes Figueiredo, Emanuelle Lira Silva, Djane Clarys Baia-da-Silva, Quique Bassat, Gustavo Romero, Gisely Cardoso Melo, Vanderson Souza Sampaio, Marcus Lacerda, and Wuelton Monteiro
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Vivax malaria ,Primaquine ,G6PD deficiency ,Brazilian Amazon ,Elimination ,Hemolysis ,Public aspects of medicine ,RA1-1270 - Abstract
Summary: Background: Difficulties associated with the assessment of glucose-6-phosphate dehydrogenase deficiency (G6PDd), particularly in remote areas, hinders the safe use of 8-aminoquinolines such as primaquine (PQ) and tafenoquine against Plasmodium vivax malaria due to the risk of haemolysis. Methods: This cross-sectional study was conducted in 41 malaria-endemic municipalities of six states in the Brazilian Amazon, between 2014 and 2018. Male individuals were screened for G6PDd using the qualitative Fluorescent Spot Test using fingerpick-collected whole blood samples. Point and interval estimates of the G6PDd prevalence were calculated for each state. Deficient samples were genotyped for the most prevalent variants in the Amazon. Frequencies of P. vivax malaria recurrences were estimated for G6PDd and non-G6PDd patients. Interpretation: This is one of the largest surveys ever conducted in Latin America, covering the entire malaria endemic area in the Brazilian Amazon. These results indicate that an important proportion of the population is at risk of hemolysis if exposed to PQ and its congener drug tafenoquine. The adoption of G6PDd screening protocols is essential to ensure the safety of individuals treated with those drugs and should also be considered when implementing malaria elimination strategies. Findings: A total of 14,847 individuals were included, of which 5.6% presented G6PDd. The state of Acre had the highest G6PDd prevalence (8.3%), followed by Amapá (5.8%), Pará (5.7%), Rondônia (5.4%), Roraima (4.2%) and Amazonas (4.0%). From 828 genotyped samples, African A+ (6.2%), African A− (39.3%) and wild-type (non-African non-Mediterranean; 54.2%) variants were found. A greater proportion of malaria recurrences was found among G6PD deficient individuals [16.7% vs 4.1%, Risk ratio 3.52 (2.16–5.74) p
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- 2022
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38. Detection of Zika Virus in Aedes aegypti and Aedes albopictus Mosquitoes Collected in Urban Forest Fragments in the Brazilian Amazon
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Erika Oliveira Gomes, Lívia Sacchetto, Maurício Teixeira, Bárbara Aparecida Chaves, Adam Hendy, Claudia Mendonça, Izabele Guimarães, Ramon Linhares, Daniela Brito, Danielle Valério, Jady Shayenne Mota Cordeiro, Alexandre Vilhena Silva Neto, Vanderson Souza Sampaio, Vera Margarete Scarpassa, Michaela Buenemann, Nikos Vasilakis, Djane Clarys Baia-da-Silva, Maurício Lacerda Nogueira, Maria Paula Gomes Mourão, and Marcus Vinícius Guimarães Lacerda
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mosquito surveillance ,arbovirus ,forest ,Amazon ,ZIKV ,Microbiology ,QR1-502 - Abstract
Zika virus (ZIKV) is an RNA flavivirus (Flaviviridae family) endemic in tropical and subtropical regions that is transmitted to humans by Aedes (Stegomyia) species mosquitoes. The two main urban vectors of ZIKV are Aedes aegypti and Aedes albopictus, which can be found throughout Brazil. This study investigated ZIKV infection in mosquito species sampled from urban forest fragments in Manaus (Brazilian Amazon). A total of 905 non-engorged female Ae. aegypti (22 specimens) and Ae. albopictus (883 specimens) were collected using BG-Sentinel traps, entomological hand nets, and Prokopack aspirators during the rainy and dry seasons between 2018 and 2021. All pools were macerated and used to inoculate C6/36 culture cells. Overall, 3/20 (15%) Ae. aegypti and 5/241 (2%) Ae. albopictus pools screened using RT-qPCR were positive for ZIKV. No supernatants from Ae. aegypti were positive for ZIKV (0%), and 15 out of 241 (6.2%) Ae. albopictus pools were positive. In this study, we provide the first-ever evidence of Ae. albopictus naturally infected with ZIKV in the Amazon region.
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- 2023
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39. Correction: Establishing a Belgian Nutrition Society (BNS): Filling the Void
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Patrice Cani, Peter Clarys, Antoine Clinquart, Stefaan De Henauw, Nathalie Delzenne, Peter Deriemaeker, Caroline Douny, Isabelle Guelinckx, Inge Huybrechts, Lieven Huybregts, Patrick Kolsteren, Carl Lachat, Isabelle Laquiere, Yvan Larondelle, Jef Leroy, Guy Manghuin-Rogister, Christophe Matthys, Patrick Mullie, Jean Neve, Marie-Louise Scippo, Isabelle Sioen, Anne-Marie Remaut, John Van Camp, Stefanie Vandevijvere, and Margareta Vansant
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Public aspects of medicine ,RA1-1270 - Published
- 2023
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40. Associations between COVID-19 and Glucose-6-Phosphate Dehydrogenase Activity in Brazil.
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de Almeida Rodrigues, Maria Gabriela, Monteiro, Wuelton Marcelo, de Melo, Gisely Cardoso, Dias, Ádila Liliane Barros, Sartim, Marco Aurélio, Xavier, Mariana Simão, Netto, Rebeca Linhares Abreu, Almeida, Fernando Fonseca, Baía-da-Silva, Djane Clarys, Brito-Sousa, José Diego, de Lacerda, Marcus Vinicius Guimarães, and Souza Sampaio, Vanderson de
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- 2024
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41. Should we care about Plasmodium vivax and HIV co-infection? A systematic review and a cases series from the Brazilian Amazon
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Del-Tejo, Paola López, Cubas-Vega, Nadia, Caraballo-Guerra, Cecilia, da Silva, Bernardo Maia, da Silva Valente, Jefferson, Sampaio, Vanderson Souza, Baia-da-Silva, Djane Clarys, Castro, Daniel Barros, Martinez-Espinosa, Flor Ernestina, Siqueira, André Machado, Lacerda, Marcus Vinícius Guimarães, Monteiro, Wuelton Marcelo, and Val, Fernando
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- 2021
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42. Determinants of changes in women’s and men’s eating behavior across the transition to parenthood: a focus group study
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Versele, Vickà, Stok, F. Marijn, Aerenhouts, Dirk, Deforche, Benedicte, Bogaerts, Annick, Devlieger, Roland, Clarys, Peter, and Deliens, Tom
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- 2021
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43. E-bikes among older adults: benefits, disadvantages, usage and crash characteristics
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Van Cauwenberg, Jelle, De Bourdeaudhuij, Ilse, Clarys, Peter, de Geus, Bas, and Deforche, Benedicte
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- 2019
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44. Correction to: Plant-based dietary patterns in Flemish adults: a 10-year trend analysis
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Deliens, Tom, Mullie, Patrick, and Clarys, Peter
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- 2022
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45. Longitudinal changes in hearing threshold levels for noise-exposed military personnel
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Collée, Audrey, Watelet, Jean-Baptiste, Vanmaele, Hanne, Van Thielen, Jozef, and Clarys, Peter
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- 2019
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46. Proinflammatory Dietary Intake Relates to Pain Sensitivity in Chronic Nonspecific Low Back Pain: A Case-Control Study
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Elma, Ömer, Tümkaya Yılmaz, Sevilay, Nijs, Jo, Clarys, Peter, Coppieters, Iris, Mertens, Evelien, Deliens, Tom, and Malfliet, Anneleen
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Nonspecific chronic low back pain (nCLBP) has been associated with nutrition. Yet, it is not clear how nutritional factors and nCLBP relate to one another. Therefore, the aim of the present study was to investigate differences in diet quality and dietary intake levels between nCLBP patients and healthy controls (HCs) and explore the association between nutritional factors and pain sensitivity in nCLBP. In this case-control study, 106 participants (ie, n = 53 nCLBP and n = 53 HCs) were recruited and completed a 3-day food diary to assess their dietary intake, which allowed to generate individual diet quality scores (ie, the Healthy Eating Index-2015 and Dietary Inflammatory Index). Additionally, each participant underwent an experimental pain assessment (quantitative sensory testing) and filled out self-reported pain questionnaires. Compared to HCs, the nCLBP group showed significantly lower diet quality, higher inflammatory scores, and a lower intake of total protein, total fat, dietary fiber, omega-3 fatty acids, vitamin B6, vitamin A, beta-carotene, vitamin E, and magnesium. Pain sensitivity mainly showed a negative correlation with nutritional intakes known for anti-inflammatory properties (ie, vitamins E, D, A, B6, B12, and zinc). Interestingly, total fat, cholesterol, saturated, and monounsaturated fat intakes were found to be inversely associated with pain sensitivity. Overall, patients with nCLBP have a lower diet quality, eat more proinflammatory, have less intake of nutrients known for their anti-inflammatory and antioxidative properties, and drink less water compared to HCs. Accordingly, pain sensitivity was mainly found to be positively associated with proinflammatory dietary intake.
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- 2024
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47. Feasibility and effectiveness of thoracic spine mobilization on sympathetic/parasympathetic balance in a healthy population - a randomized controlled double-blinded pilot study
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Rogan, Slavko, Taeymans, Jan, Clarys, Peter, Clijsen, Ron, and Tal-Akabi, Amir
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- 2019
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48. Some further clarifications on age-related differences in Stroop interference
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Augustinova, Maria, Clarys, David, Spatola, Nicolas, and Ferrand, Ludovic
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- 2018
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49. The Physically Active Lifestyle of Flemish Secondary School Teachers: A Mixed-Methods Approach towards Developing a Physical Activity Intervention
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Bogaert, Inge, De Martelaer, Kristine, Deforche, Benedicte, Clarys, Peter, and Zinzen, Evert
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Objective: The primary aim of this study was to describe and analyse the physical activity and sedentary levels of secondary school teachers in Flanders. A secondary aim was to collect information regarding a possible worksite intervention of special relevance to secondary school teachers. Design: Mixed-methods quantitative and qualitative enquiry. Setting: Secondary school teachers in Flanders. Method: An online survey was conducted consisting of the International Physical Activity Questionnaire, demographic information and teaching aspects. Additionally, four focus groups (n = 27) took place. Results: Respondents reported an average of 137.2 ± 96.8 minutes/day of physical activity and an average sitting time of 4.6 ± 4.2 hours/day. Overall, 66% of Flemish teachers met the physical activity guidelines of at least 150 minutes of moderate to vigorous activity a week. Lower levels of activity were more prevalent among female teachers, teachers working in technical and general education and those teaching theoretical courses. In focus group discussions, two types of barriers were identified influencing teachers' physical activity at school: organisational barriers such as planning and lack of accommodation, and individual barriers such as having other responsibilities. Conclusions: Interventions can be developed to target less active teachers. However, a classic worksite physical activity intervention during working hours is not suitable for most teachers. Promoting leisure-time activity and active commuting are more fitting components of an intervention for this target group. Actions at school should be achievable and unforced, supporting teachers' development of physical literacy.
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- 2015
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50. Stability of physical activity, fitness components and diet quality indices
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Mertens, E, Clarys, P, Mullie, P, Lefevre, J, Charlier, R, Knaeps, S, Huybrechts, I, and Deforche, B.
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Exercise -- Health aspects ,Physical fitness -- Health aspects ,Diet -- Health aspects ,Food/cooking/nutrition ,Health - Abstract
Background: Regular physical activity (PA), a high level of fitness and a high diet quality are positively associated with health. However, information about stability of fitness components and diet quality indices is limited. This study aimed to evaluate stability of those parameters. Methods: This study includes 652 adults (men=57.56 (10.28) years; women=55.90 (8.34) years at follow-up) who participated in 2002-2004 and returned for follow-up at the Policy Research Centre Leuven in 2012-2014. Minutes sport per day and Physical activity level (PAL) were calculated from the Flemish Physical Activity Computerized Questionnaire. Cardiorespiratory fitness (CRF), morphological fitness (MORF; body mass index and waist circumference) and metabolic fitness (METF) (blood cholesterol and triglycerides) were used as fitness components. Diet quality indices (Healthy Eating Index-2010 (HEI), Diet Quality Index (DQI), Mediterranean Diet Score (MDS)) were calculated from a diet record. Tracking coefficients were calculated using Pearson/Spearman correlation coefficients (r.sub.Pearson) and intra-class correlation coefficients (r.sub.ICC). Results: In both men (r.sub.Pearson&ICC=0.51) and women (r.sub.Pearson=0.62 and r.sub.ICC=0.60) PAL showed good stability, while minutes sport remained stable in women (r.sub.Pearson&ICC=0.57) but less in men (r.sub.Pearson&ICC=0.45). Most fitness components remained stable (r[greater-than or slanted equal to]0.50) except some METF components in women. In general the diet quality indices and their components were unstable (r Conclusions: PAL and the majority of the fitness components remained stable, while diet quality was unstable over 10 years. For unstable parameters such as diet quality measurements are needed at both time points in prospective research., Author(s): E Mertens [sup.1] [sup.2] , P Clarys [sup.1] [sup.3] , P Mullie [sup.1] [sup.3] [sup.4] , J Lefevre [sup.2] , R Charlier [sup.2] , S Knaeps [sup.2] [sup.5] , [...]
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- 2017
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