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2. Pathological findings associated with the updated European Society of Cardiology 2022 guidelines for preoperative cardiac testing: an observational cohort modelling study

Author

Kemper, Johann, Kohaupt, Lena, Witzler, Jette, Tuzhikov, Michael, Roth, Sebastian, Stroda, Alexandra, M’Pembele, René, Tenge, Theresa, Schultze, Cornelia, Verbarg, Nele, Gehrke, Christian, Klemann, Anna Katharina, Hagebölling, Friederike, Albrecht, Svenja, Stroeder, Jakob, Schubert, Ann-Kristin, Espeter, Florian, Russe, Benedikt, Weigand, Markus A., Bergmann, Lars, Unterberg, Matthias, Bischoff, Petra, Pirzer, Raphael, Rach, Patric Rene, Ott, Klaus, Zarbock, Alexander, Kowark, Ana, Neumann, Claudia, Marchand, Bahareh, Sponholz, Christoph, Rueffert, Henrik, Kramer, Mira, Zacharowski, Kai, Meybohm, Patrick, Lindau, Simone, Carollo, Melissa, Novazzi, Cecilia, Toso, Fiorenza, Bacuzzi, Alessandro, Ragazzi, Riccardo, Volta, Carlo Alberto, De Giorgi, Francesco, Bacer, Barbara, Federico, Antonio, Chiumello, Davide, Vetrugno, Luigi, Castella, Alberto, Tesoro, Simonetta, Cotoia, Antonella, Bignami, Elena, Bellissima, Agrippino, Cortegiani, Andrea, Crisman, Marco, Toninelli, Arturo, Piazza, Ornella, Mirabella, Lucia, Bossolasco, Matteo, Bona, Francesco, Perdomo, Juan Manuel, Coca-Martinez, Miquel, Carramiñana, Albert, Servén, Marta Giné, González, Astrid Batalla, Gil Sánchez, José Maria, Becerra-Bolaños, Ángel, Rodríguez-Pérez, Aurelio, Soler, Anna Artigas, Basso, Morena, Font, Anna Peig, Vernetta, Diana, Santos, Julia Hernando, Muñoz, Enrique Alday, Olivares, Mercedes Cabellos, Marco, Gregorio, Lopez, Maria Bermudez, Barrio, Javier, Forés, María Isabel, Boix, Estefanía, Ayuso, Mercedes, Petre, Bogdan Sorel, Oprea, Ioana Sorina, Latiș, Mihai Dan, Margarit, Simona, Vasian, Horatiu, Tomescu, Dana, Cîndea, Iulia, Dirzu, Dan Sebastian, Copotoiu, Sanda-Maria, Moise, Alida, Bubenek-Turconi, Serban, Valeanu, Liana, Wanner, Patrick Mark, Djurdjevic, Mirjana, Nuth, Sandra, Seeberger, Esther, Goettel, Nicolai, Kamber, Firmin, Ganter, Michael Thomas, Gerber, Thomas Jan, Schneebeli, Daniela, Pregernig, Andreas, Grape, Sina, Tomala, Simon, Pinto, Bernardo Bollen, Żukowski, Maciej, Zegan-Barańska, Małgorzata, Karolak, Igor, Krzych, Lukasz, Czajka, Szymon, Studzińska, Dorota, Kluzik, Anna, Koszel, Tomasz, Pabjańczyk, Izabela, Gajdosz, Anna, Erkoc, Suheyla Karadag, Meco, Basak Ceyda, Koltka, Ahmet Kemalettin, Dincer, Muserref Beril, Ekmekçi, Perihan, Saracoglu, Kemal Tolga, Solmaz, Filiz Alkaya, Ozcelik, Menekse, Arun, Oguzhan, Dilmen, Ozlem Korkmaz, Preckel, Benedikt, Hollmann, Markus W., Hazen, Yannick, Donald de Boer, Hans, Epema, Anne, Koopman, Seppe, Van Lier, Felix, Pinto, Rita, Carrão, André, Ribeiro, Daniel, Mourão, Joana, Coelho, Miguel, Losa, Nuno, Santos, Nuno, Cabral, Luis, Afonso, Diana, Zenha, Sérgio, Ramos, Cristina, Hipólito, Carla, Vasilaki, Maria, Andreeva, Antonia, Zaimi, Donika, Chalkias, Athanasios, Spyraki, Maria, Rekatsina, Martina, Tsaousi, Georgia, Short, Anthony, Meier, Sonja, Madhuri, Thumuluru Kavitha, Latham, Scott, Knock, James, Drummond, Andrew, Ramsden, Fiona, Kubisz-Pudelko, Agnieszka, Walker, James, Moppett, Iain, White, Louise, Jackson, Matthew, Reschreiter, Henrik, Innes, Richard, Chew, Michelle, Kalman, Sigridur, Wallden, Jakob, Schening, Anna, Jonikaite, Lina, Enlund, Anna, De Baerdemaeker, Luc, Morrison, Stuart, Rex, Steffen, Alexis, Alexandros, Khoronenko, Viktoria E., Ovezov, Alexey, Belskii, Vladislav, Kaznacheeva, Kseniya, Gritsan, Alexey, Kuzmanovska, Biljana, Malinovska-Nikolovska, Liljana, Barisin, Stjepan, Poredos, Peter, Arabadzhieva, Daniela, Unic-Stojanovic, Dragana, Golubović, Mladjan, Fleischmann, Edith, Kotzinger, Oskar, Des Deserts, Marc Danguy, Ducrocq, Nicolas, Buggy, Donal J., Bonnet, Jean François, Cusack, Barbara, Calleja, Paul, Hasani, Antigona, Nallbani, Rajmonda, Mauermann, Eckhard, Ionescu, Daniela, Szczeklik, Wojciech, De Hert, Stefan, Filipovic, Miodrag, Beck Schimmer, Beatrice, Spadaro, Savino, Matute, Purificación, Ganter, Michael T., Turhan, Sanem C., van Waes, Judith, Lagarto, Filipa, Theodoraki, Kassiani, Gupta, Anil, Gillmann, Hans-Jörg, Guzzetti, Luca, Kotfis, Katarzyna, Larmann, Jan, Corneci, Dan, Howell, Simon J., and Lurati Buse, Giovanna more...

Published
2024
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3. Risk assessment for major adverse cardiovascular events after noncardiac surgery using self-reported functional capacity: international prospective cohort study

Author

Lurati, Giovanna, Spadaro, Savino, Matute, Purificación, Ionescu, Daniela, Bolliger, Daniel, Szczeklik, Wojciech, Turhan, Sanem Cakar, van Waes, Judith, Lagarto, Filipa, Theodoraki, Kassiani, Howell, Simon J., Gupta, Anil, De Hert, Stefan, Ovezov, Alexey, Tollinche, Luis E., Kuzmanovska, Biljana, Barisin, Stjepan, Poredos, Peter, Arabadzhieva, Daniela, Unic-Stojanovic, Dragana, Fleischmann, Edith, Meistelman, Claude, Buggy, Donal J., Calleja, Paul, Hasani, Antigona, Kemper, Johann, Kohaupt, Lena, Witzler, Jette, Tuzhikov, Michael, Roth, Sebastian, Stroda, Alexandra, Schultze, Cornelia, Verbarg, Nele, Gehrke, Christian, Klemann, Anna Katharina, Hagebölling, Friederike, Albrecht, Svenja, Stroeder, Jakob, Schubert, Ann-Kristin, Espeter, Florian, Russe, Benedikt, Weigand, Markus A., Bergmann, Lars, Unterberg, Matthias, Bischoff, Petra, Pirzer, Raphael, Rach, Patric Rene, Ott, Klaus, Zarbock, Alexander, Kowark, Ana, Neumann, Claudia, Marchand, Bahareh, Sponholz, Christoph, Rueffert, Henrik, Kramer, Mira, Piekarski, Florian, Carollo, Melissa, Novazzi, Cecilia, Toso, Fiorenza, Bacuzzi, Alessandro, Ragazzi, Riccardo, Volta, Carlo Alberto, De Giorgi, Francesco, Bacer, Barbara, Federico, Antonio, Chiumello, Davide, Vetrugno, Luigi, Castella, Alberto, Tesoro, Simonetta, Cotoia, Antonella, Bignami, Elena, Bellissima, Agrippino, Cortegiani, Andrea, Crisman, Marco, Toninelli, Arturo, Piazza, Ornella, Mirabella, Lucia, Bossolasco, Matteo, Bona, Francesco, Perdomo, Juan Manuel, Coca-Martinez, Miquel, Carramiñana, Albert, Servén, Marta Giné, González, Astrid Batalla, Gil Sánchez, José Maria, Becerra-Bolaños, Ángel, Rodríguez-Pérez, Aurelio, Soler, Anna Artigas, Basso, Morena, Font, Anna Peig, Vernetta, Diana, Santos, Julia Hernando, Muñoz, Enrique Alday, Olivares, Mercedes Cabellos, Marco, Gregorio, Lopez, Maria Bermudez, Barrio, Javier, Forés, María Isabel, Boix, Estefanía, Ayuso, Mercedes, Petre, Bogdan Sorel, Oprea, Ioana Sorina, Latiș, Mihai Dan, Margarit, Simona, Vasian, Horatiu, Tomescu, Dana, Cîndea, Iulia, Dirzu, Dan Sebastian, Copotoiu, Sanda-Maria, Moise, Alida, Bubenek-Turconi, Serban, Valeanu, Liana, Wanner, Patrick Mark, Djurdjevic, Mirjana, Nuth, Sandra, Seeberger, Esther, Goettel, Nicolai, Kamber, Firmin, Ganter, Michael Thomas, Gerber, Thomas Jan, Schneebeli, Daniela, Pregernig, Andreas, Grape, Sina, Tomala, Simon, Pinto, Bernardo Bollen, Żukowski, Maciej, Zegan-Barańska, Małgorzata, Karolak, Igor, Krzych, Lukasz, Czajka, Szymon, Studzińska, Dorota, Kluzik, Anna, Koszel, Tomasz, Pabjańczyk, Izabela, Gajdosz, Anna, Erkoc, Suheyla Karadag, Meco, Basak Ceyda, Koltka, Ahmet Kemalettin, Dincer, Muserref Beril, Ekmekçi, Perihan, Saracoglu, Kemal Tolga, Solmaz, Filiz Alkaya, Ozcelik, Menekse, Arun, Oguzhan, Dilmen, Ozlem Korkmaz, Preckel, Benedikt, Hollmann, Markus W., Hazen, Yannick, Donald de Boer, Hans, Epema, Anne, Koopman, Seppe, Van Lier, Felix, Pinto, Rita, Carrão, André, Ribeiro, Daniel, Mourão, Joana, Coelho, Miguel, Losa, Nuno, Santos, Nuno, Cabral, Luis, Afonso, Diana, Zenha, Sérgio, Ramos, Cristina, Hipólito, Carla, Vasilaki, Maria, Andreeva, Antonia, Zaimi, Donika, Chalkias, Athanasios, Spyraki, Maria, Rekatsina, Martina, Tsaousi, Georgia, Short, Anthony, Meier, Sonja, Madhuri, Thumuluru Kavitha, Latham, Scott, Knock, James, Drummond, Andrew, Ramsden, Fiona, Kubisz-Pudelko, Agnieszka, Walker, James, Moppett, Iain, White, Louise, Jackson, Matthew, Reschreiter, Henrik, Innes, Richard, Chew, Michelle, Kalman, Sigridur, Wallden, Jakob, Schening, Anna, Jonikaite, Lina, Enlund, Anna, De Baerdemaeker, Luc, Morrison, Stuart, Rex, Steffen, Alexis, Alexandros, Khoronenko, Viktoria E., Belskii, Vladislav, Kaznacheeva, Kseniya, Gritsan, Alexey, Yeoh, Cindy B., Malinovska-Nikolovska, Liljana, Golubović, Mladjan, Kotzinger, Oskar, Des Deserts, Marc Danguy, Ducrocq, Nicolas, Bonnet, Jean François, Cusack, Barbara, Nallbani, Rajmonda, Daamen, Sylvia, Plichon, Benoit, Harlet, Pierre, Farsi, Slama, Sepehr, Saman Homayun, Espinosa, David, Lurati Buse, Giovanna A., Mauermann, Eckhard, Filipovic, Miodrag, Beck-Schimmer, Beatrice, Gillmann, Hans-Jörg, Guzzetti, Luca, Kotfis, Katarzyna, Wulf, Hinnerk, Larmann, Jan, Corneci, Dan, and Chammartin-Basnet, Frederique more...

Published
2023
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8. Multimodal prehabilitation to enhance functional capacity of patients with esophageal cancer during concurrent neoadjuvant chemotherapies—a randomized feasibility trial.

Author

St-Pierre, Jade, Coca-Martinez, Miquel, Drummond, Kenneth, Minnella, Enrico, Ramanakumar, Agnihotram V, Ferri, Lorenzo, Carli, Franco, and Scheede-Bergdahl, Celena

Subjects
*PREHABILITATION, *CARDIOPULMONARY fitness, *ESOPHAGEAL tumors, *ESOPHAGEAL cancer, *SOCIAL support
Abstract

Esophageal adenocarcinoma continues to bear high morbidity and mortality. Prehabilitation, using exercise, nutrition, and psychosocial strategies to optimize patients prior to surgical resection, is largely underexplored in this malignancy, especially in patients undergoing neoadjuvant chemotherapy. Objectives of this study were (i) to determine feasibility of prehabilitation during treatment in patients with esophageal cancer and (ii) to establish differences between hospital and home-based exercise. Patients were recruited from August 2019 – February 2023 and blindly randomized to either supervised or homebased exercise, receiving identical nutritional and psychosocial support. The main outcome measures were recruitment, retention, and dropout rates. The secondary outcomes included cardiorespiratory fitness, functional capacity, and quality of life. Forty-four subjects were blindly randomized: 23 to supervised exercise and 21 to home-based exercise (72% recruitment rate). Overall compliance for the supervised group was 72%; home-based group was 77%. Baseline to pre-operative, both groups experienced significant increases in sit-to-stand, arm curls, and amount of weekly moderate–vigorous physical activity. The home-based group experienced an additional considerable decrease in up-and-go test times. Both groups maintained cardiorespiratory fitness and saw substantial increases in some quality-of-life scores. Multimodal prehabilitation is feasible for patients with esophageal cancer undergoing neoadjuvant chemotherapy. In both groups, patient fitness, which is relevant for this patient population given the anticipated decline in functional status during this period, was maintained. This study provides a foundation for future prehabilitation interventions in this patient population. [ABSTRACT FROM AUTHOR] more...

Published
2024
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9. Pathological findings associated with the updated European Society of Cardiology 2022 guidelines for preoperative cardiac testing: an observational cohort modelling study

Author

Stroda, Alexandra, primary, Mauermann, Eckhard, additional, Ionescu, Daniela, additional, Szczeklik, Wojciech, additional, De Hert, Stefan, additional, Filipovic, Miodrag, additional, Beck Schimmer, Beatrice, additional, Spadaro, Savino, additional, Matute, Purificación, additional, Ganter, Michael T., additional, Ovezov, Alexey, additional, Turhan, Sanem C., additional, van Waes, Judith, additional, Lagarto, Filipa, additional, Theodoraki, Kassiani, additional, Gupta, Anil, additional, Gillmann, Hans-Jörg, additional, Guzzetti, Luca, additional, Kotfis, Katarzyna, additional, Larmann, Jan, additional, Corneci, Dan, additional, Buggy, Donal J., additional, Howell, Simon J., additional, Lurati Buse, Giovanna, additional, Kemper, Johann, additional, Kohaupt, Lena, additional, Witzler, Jette, additional, Tuzhikov, Michael, additional, Roth, Sebastian, additional, Stroda, Alexandra, additional, M’Pembele, René, additional, Tenge, Theresa, additional, Schultze, Cornelia, additional, Verbarg, Nele, additional, Gehrke, Christian, additional, Klemann, Anna Katharina, additional, Hagebölling, Friederike, additional, Albrecht, Svenja, additional, Stroeder, Jakob, additional, Schubert, Ann-Kristin, additional, Espeter, Florian, additional, Russe, Benedikt, additional, Weigand, Markus A., additional, Bergmann, Lars, additional, Unterberg, Matthias, additional, Bischoff, Petra, additional, Pirzer, Raphael, additional, Rach, Patric Rene, additional, Ott, Klaus, additional, Zarbock, Alexander, additional, Kowark, Ana, additional, Neumann, Claudia, additional, Marchand, Bahareh, additional, Sponholz, Christoph, additional, Rueffert, Henrik, additional, Kramer, Mira, additional, Zacharowski, Kai, additional, Meybohm, Patrick, additional, Lindau, Simone, additional, Carollo, Melissa, additional, Novazzi, Cecilia, additional, Toso, Fiorenza, additional, Bacuzzi, Alessandro, additional, Ragazzi, Riccardo, additional, Volta, Carlo Alberto, additional, De Giorgi, Francesco, additional, Bacer, Barbara, additional, Federico, Antonio, additional, Chiumello, Davide, additional, Vetrugno, Luigi, additional, Castella, Alberto, additional, Tesoro, Simonetta, additional, Cotoia, Antonella, additional, Bignami, Elena, additional, Bellissima, Agrippino, additional, Cortegiani, Andrea, additional, Crisman, Marco, additional, Toninelli, Arturo, additional, Piazza, Ornella, additional, Mirabella, Lucia, additional, Bossolasco, Matteo, additional, Bona, Francesco, additional, Perdomo, Juan Manuel, additional, Coca-Martinez, Miquel, additional, Carramiñana, Albert, additional, Servén, Marta Giné, additional, González, Astrid Batalla, additional, Gil Sánchez, José Maria, additional, Becerra-Bolaños, Ángel, additional, Rodríguez-Pérez, Aurelio, additional, Soler, Anna Artigas, additional, Basso, Morena, additional, Font, Anna Peig, additional, Vernetta, Diana, additional, Santos, Julia Hernando, additional, Muñoz, Enrique Alday, additional, Olivares, Mercedes Cabellos, additional, Marco, Gregorio, additional, Lopez, Maria Bermudez, additional, Barrio, Javier, additional, Forés, María Isabel, additional, Boix, Estefanía, additional, Ayuso, Mercedes, additional, Petre, Bogdan Sorel, additional, Oprea, Ioana Sorina, additional, Latiș, Mihai Dan, additional, Margarit, Simona, additional, Vasian, Horatiu, additional, Tomescu, Dana, additional, Cîndea, Iulia, additional, Dirzu, Dan Sebastian, additional, Copotoiu, Sanda-Maria, additional, Moise, Alida, additional, Bubenek-Turconi, Serban, additional, Valeanu, Liana, additional, Wanner, Patrick Mark, additional, Djurdjevic, Mirjana, additional, Nuth, Sandra, additional, Seeberger, Esther, additional, Goettel, Nicolai, additional, Kamber, Firmin, additional, Ganter, Michael Thomas, additional, Gerber, Thomas Jan, additional, Schneebeli, Daniela, additional, Pregernig, Andreas, additional, Grape, Sina, additional, Tomala, Simon, additional, Pinto, Bernardo Bollen, additional, Żukowski, Maciej, additional, Zegan-Barańska, Małgorzata, additional, Karolak, Igor, additional, Krzych, Lukasz, additional, Czajka, Szymon, additional, Studzińska, Dorota, additional, Kluzik, Anna, additional, Koszel, Tomasz, additional, Pabjańczyk, Izabela, additional, Gajdosz, Anna, additional, Erkoc, Suheyla Karadag, additional, Meco, Basak Ceyda, additional, Koltka, Ahmet Kemalettin, additional, Dincer, Muserref Beril, additional, Ekmekçi, Perihan, additional, Saracoglu, Kemal Tolga, additional, Solmaz, Filiz Alkaya, additional, Ozcelik, Menekse, additional, Arun, Oguzhan, additional, Dilmen, Ozlem Korkmaz, additional, Preckel, Benedikt, additional, Hollmann, Markus W., additional, Hazen, Yannick, additional, Donald de Boer, Hans, additional, Epema, Anne, additional, Koopman, Seppe, additional, Van Lier, Felix, additional, Pinto, Rita, additional, Carrão, André, additional, Ribeiro, Daniel, additional, Mourão, Joana, additional, Coelho, Miguel, additional, Losa, Nuno, additional, Santos, Nuno, additional, Cabral, Luis, additional, Afonso, Diana, additional, Zenha, Sérgio, additional, Ramos, Cristina, additional, Hipólito, Carla, additional, Vasilaki, Maria, additional, Andreeva, Antonia, additional, Zaimi, Donika, additional, Chalkias, Athanasios, additional, Spyraki, Maria, additional, Rekatsina, Martina, additional, Tsaousi, Georgia, additional, Short, Anthony, additional, Meier, Sonja, additional, Madhuri, Thumuluru Kavitha, additional, Latham, Scott, additional, Knock, James, additional, Drummond, Andrew, additional, Ramsden, Fiona, additional, Kubisz-Pudelko, Agnieszka, additional, Walker, James, additional, Moppett, Iain, additional, White, Louise, additional, Jackson, Matthew, additional, Reschreiter, Henrik, additional, Innes, Richard, additional, Chew, Michelle, additional, Kalman, Sigridur, additional, Wallden, Jakob, additional, Schening, Anna, additional, Jonikaite, Lina, additional, Enlund, Anna, additional, De Baerdemaeker, Luc, additional, Morrison, Stuart, additional, Rex, Steffen, additional, Alexis, Alexandros, additional, Khoronenko, Viktoria E., additional, Belskii, Vladislav, additional, Kaznacheeva, Kseniya, additional, Gritsan, Alexey, additional, Kuzmanovska, Biljana, additional, Malinovska-Nikolovska, Liljana, additional, Barisin, Stjepan, additional, Poredos, Peter, additional, Arabadzhieva, Daniela, additional, Unic-Stojanovic, Dragana, additional, Golubović, Mladjan, additional, Fleischmann, Edith, additional, Kotzinger, Oskar, additional, Des Deserts, Marc Danguy, additional, Ducrocq, Nicolas, additional, Bonnet, Jean François, additional, Cusack, Barbara, additional, Calleja, Paul, additional, Hasani, Antigona, additional, and Nallbani, Rajmonda, additional more...

Published
2024
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10. Association between self-reported functional capacity and general postoperative complications: analysis of predefined outcomes of the MET-REPAIR international cohort study

Author

Roth, Sebastian, primary, M'Pembele, René, additional, Nienhaus, Johannes, additional, Mauermann, Eckhard, additional, Ionescu, Daniela, additional, Szczeklik, Wojciech, additional, De Hert, Stefan, additional, Filipovic, Miodrag, additional, Beck-Schimmer, Beatrice, additional, Spadaro, Savino, additional, Matute, Purificación, additional, Bolliger, Daniel, additional, Turhan, Sanem C., additional, van Waes, Judith, additional, Lagarto, Filipa, additional, Theodoraki, Kassiani, additional, Gupta, Anil, additional, Gillmann, Hans-Jörg, additional, Guzzetti, Luca, additional, Kotfis, Katarzyna, additional, Wulf, Hinnerk, additional, Larmann, Jan, additional, Corneci, Dan, additional, Chammartin, Frédérique, additional, Howell, Simon J., additional, Lurati Buse, Giovanna, additional, Roth, Sebastian, additional, Kemper, Johann, additional, Kohaupt, Lena, additional, Witzler, Jette, additional, Tuzhikov, Michael, additional, Stroda, Alexandra, additional, Tenge, Theresa, additional, Huhn, Ragnar, additional, Schultze, Cornelia, additional, Verbarg, Nele, additional, Gehrke, Christian, additional, Klemann, Anna Katharina, additional, Hagebölling, Friederike, additional, Albrecht, Svenja, additional, Stroeder, Jakob, additional, Schubert, Ann-Kristin, additional, Espeter, Florian, additional, Russe, Benedikt, additional, Weigand, Markus A., additional, Bergmann, Lars, additional, Unterberg, Matthias, additional, Bischoff, Petra, additional, Pirzer, Raphael, additional, Rach, Patric Rene, additional, Ott, Klaus, additional, Zarbock, Alexander, additional, Kowark, Ana, additional, Neumann, Claudia, additional, Marchand, Bahareh, additional, Sponholz, Christoph, additional, Rueffert, Henrik, additional, Kramer, Mira, additional, Piekarski, Florian, additional, Carollo, Melissa, additional, Novazzi, Cecilia, additional, Toso, Fiorenza, additional, Bacuzzi, Alessandro, additional, Ragazzi, Riccardo, additional, Volta, Carlo Alberto, additional, De Giorgi, Francesco, additional, Bacer, Barbara, additional, Federico, Antonio, additional, Chiumello, Davide, additional, Vetrugno, Luigi, additional, Castella, Alberto, additional, Tesoro, Simonetta, additional, Cotoia, Antonella, additional, Bignami, Elena, additional, Bellissima, Agrippino, additional, Cortegiani, Andrea, additional, Crisman, Marco, additional, Toninelli, Arturo, additional, Piazza, Ornella, additional, Mirabella, Lucia, additional, Bossolasco, Matteo, additional, Bona, Francesco, additional, Perdomo, Juan Manuel, additional, Coca-Martinez, Miquel, additional, Carramiñana, Albert, additional, Servén, Marta Giné, additional, González, Astrid Batalla, additional, Gil Sánchez, José Maria, additional, Becerra-Bolaños, Ángel, additional, Rodríguez-Pérez, Aurelio, additional, Soler, Anna Artigas, additional, Basso, Morena, additional, Font, Anna Peig, additional, Vernetta, Diana, additional, Santos, Julia Hernando, additional, Muñoz, Enrique Alday, additional, Olivares, Mercedes Cabellos, additional, Marco, Gregorio, additional, Lopez, Maria Bermudez, additional, Barrio, Javier, additional, Forés, María Isabel, additional, Boix, Estefanía, additional, Ayuso, Mercedes, additional, Petre, Bogdan Sorel, additional, Oprea, Ioana Sorina, additional, Latiș, Mihai Dan, additional, Margarit, Simona, additional, Vasian, Horatiu, additional, Tomescu, Dana, additional, Cîndea, Iulia, additional, Dirzu, Dan Sebastian, additional, Copotoiu, Sanda-Maria, additional, Moise, Alida, additional, Bubenek-Turconi, Serban, additional, Valeanu, Liana, additional, Wanner, Patrick Mark, additional, Djurdjevic, Mirjana, additional, Nuth, Sandra, additional, Seeberger, Esther, additional, Goettel, Nicolai, additional, Kamber, Firmin, additional, Ganter, Michael Thomas, additional, Gerber, Thomas Jan, additional, Schneebeli, Daniela, additional, Pregernig, Andreas, additional, Grape, Sina, additional, Tomala, Simon, additional, Pinto, Bernardo Bollen, additional, Żukowski, Maciej, additional, Zegan-Barańska, Małgorzata, additional, Karolak, Igor, additional, Krzych, Lukasz, additional, Czajka, Szymon, additional, Studzińska, Dorota, additional, Kluzik, Anna, additional, Koszel, Tomasz, additional, Pabjańczyk, Izabela, additional, Gajdosz, Anna, additional, Erkoc, Suheyla Karadag, additional, Meco, Basak Ceyda, additional, Koltka, Ahmet Kemalettin, additional, Dincer, Muserref Beril, additional, Ekmekçi, Perihan, additional, Saracoglu, Kemal Tolga, additional, Solmaz, Filiz Alkaya, additional, Ozcelik, Menekse, additional, Arun, Oguzhan, additional, Dilmen, Ozlem Korkmaz, additional, Preckel, Benedikt, additional, Hollmann, Markus W., additional, Hazen, Yannick, additional, Donald de Boer, Hans, additional, Epema, Anne, additional, Koopman, Seppe, additional, Van Lier, Felix, additional, Pinto, Rita, additional, Carrão, André, additional, Ribeiro, Daniel, additional, Mourão, Joana, additional, Coelho, Miguel, additional, Santos, Nuno, additional, Cabral, Luis, additional, Afonso, Diana, additional, Zenha, Sérgio, additional, Ramos, Cristina, additional, Hipólito, Carla, additional, Vasilaki, Maria, additional, Andreeva, Antonia, additional, Zaimi, Donika, additional, Chalkias, Athanasios, additional, Spyraki, Maria, additional, Rekatsina, Martina, additional, Tsaousi, Georgia, additional, Short, Anthony, additional, Meier, Sonja, additional, Madhuri, Thumuluru Kavitha, additional, Latham, Scott, additional, Knock, James, additional, Drummond, Andrew, additional, Ramsden, Fiona, additional, Kubisz-Pudelko, Agnieszka, additional, Walker, James, additional, Moppett, Iain, additional, White, Louise, additional, Jackson, Matthew, additional, Reschreiter, Henrik, additional, Innes, Richard, additional, Chew, Michelle, additional, Kalman, Sigridur, additional, Wallden, Jakob, additional, Schening, Anna, additional, Jonikaite, Lina, additional, Enlund, Anna, additional, De Baerdemaeker, Luc, additional, Morrison, Stuart, additional, Rex, Steffen, additional, Alexis, Alexandros, additional, Khoronenko, Viktoria E., additional, Ovezov, Alexey, additional, Belskii, Vladislav, additional, Kaznacheeva, Kseniya, additional, Gritsan, Alexey, additional, Kuzmanovska, Biljana, additional, Malinovska-Nikolovska, Liljana, additional, Barisin, Stjepan, additional, Poredos, Peter, additional, Arabadzhieva, Daniela, additional, Unic-Stojanovic, Dragana, additional, Golubović, Mladjan, additional, Fleischmann, Edith, additional, Kotzinger, Oskar, additional, Des Deserts, Marc Danguy, additional, Ducrocq, Nicolas, additional, Buggy, Donal J., additional, Bonnet, Jean François, additional, Cusack, Barbara, additional, Calleja, Paul, additional, Hasani, Antigona, additional, and Nallbani, Rajmonda, additional more...

Published
2024
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12. Multimodal prehabilitation for peripheral arterial disease patients with intermittent claudication - A pilot randomized controlled trial.

Author

Coca-Martinez, Miquel, primary, Girsowicz, Elie, additional, Doonan, Robert J., additional, Obrand, Daniel I., additional, Bayne, Jason P., additional, Steinmetz, Oren K., additional, Mackenzie, Kent S., additional, Carli, Francesco, additional, Martinez-Palli, Graciela, additional, and Gill, Heather L., additional more...

Published
2023
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15. Advances in the Management of Acute Postsurgical Pain: A Review

Author

Paladini, Antonella, primary, Rawal, Narinder, additional, Coca Martinez, Miquel, additional, Trifa, Mehdi, additional, Montero, Antonio, additional, Pergolizzi, Joseph, additional, Pasqualucci, Alberto, additional, Narvaez Tamayo, Marco Antonio, additional, Varrassi, Giustino, additional, and De Leon Casasola, Oscar, additional more...

Published
2023
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16. Effect of Multimodal Prehabilitation on Reducing Postoperative Complications and Enhancing Functional Capacity Following Colorectal Cancer Surgery:The PREHAB Randomized Clinical Trial

Author

Molenaar, Charlotte Johanna Laura, Minnella, Enrico Maria, Coca-Martinez, Miquel, Ten Cate, David Wouter Gerard, Regis, Marta, Awasthi, Rashami, Martínez-Palli, Graciela, López-Baamonde, Manuel, Sebio-Garcia, Raquel, Feo, Carlo Vittorio, Van Rooijen, Stefanus Johannes, Schreinemakers, Jennifer Marijke Janneke, Bojesen, Rasmus Dahlin, Gögenur, Ismail, Van Den Heuvel, Edwin R., Carli, Francesco, Slooter, Gerrit Dirk, Molenaar, Charlotte Johanna Laura, Minnella, Enrico Maria, Coca-Martinez, Miquel, Ten Cate, David Wouter Gerard, Regis, Marta, Awasthi, Rashami, Martínez-Palli, Graciela, López-Baamonde, Manuel, Sebio-Garcia, Raquel, Feo, Carlo Vittorio, Van Rooijen, Stefanus Johannes, Schreinemakers, Jennifer Marijke Janneke, Bojesen, Rasmus Dahlin, Gögenur, Ismail, Van Den Heuvel, Edwin R., Carli, Francesco, and Slooter, Gerrit Dirk more...

Abstract

Importance: Colorectal surgery is associated with substantial morbidity rates and a lowered functional capacity. Optimization of the patient's condition in the weeks prior to surgery may attenuate these unfavorable sequelae. Objective: To determine whether multimodal prehabilitation before colorectal cancer surgery can reduce postoperative complications and enhance functional recovery. Design, Setting, and Participants: The PREHAB randomized clinical trial was an international, multicenter trial conducted in teaching hospitals with implemented enhanced recovery after surgery programs. Adult patients with nonmetastasized colorectal cancer were assessed for eligibility and randomized to either prehabilitation or standard care. Both arms received standard perioperative care. Patients were enrolled from June 2017 to December 2020, and follow-up was completed in December 2021. However, this trial was prematurely stopped due to the COVID-19 pandemic. Interventions: The 4-week in-hospital supervised multimodal prehabilitation program consisted of a high-intensity exercise program 3 times per week, a nutritional intervention, psychological support, and a smoking cessation program when needed. Main Outcomes and Measures: Comprehensive Complication Index (CCI) score, number of patients with CCI score more than 20, and improved walking capacity expressed as the 6-minute walking distance 4 weeks postoperatively. Results: In the intention-to-treat population of 251 participants (median [IQR] age, 69 [60-76] years; 138 [55%] male), 206 (82%) had tumors located in the colon and 234 (93%) underwent laparoscopic- or robotic-assisted surgery. The number of severe complications (CCI score >20) was significantly lower favoring prehabilitation compared with standard care (21 of 123 [17.1%] vs 38 of 128 [29.7%]; odds ratio, 0.47 [95% CI, 0.26-0.87]; P =.02). Participants in prehabilitation encountered fewer medical complications (eg, respiratory) compared with participants receivin more...

Published
2023

17. Effect of Multimodal Prehabilitation on Reducing Postoperative Complications and Enhancing Functional Capacity Following Colorectal Cancer Surgery: The PREHAB Randomized Clinical Trial.

Author

Molenaar, Charlotte Johanna Laura, Minnella, Enrico Maria, Coca-Martinez, Miquel, ten Cate, David Wouter Gerard, Regis, Marta, Awasthi, Rashami, Martínez-Palli, Graciela, López-Baamonde, Manuel, Sebio-Garcia, Raquel, Feo, Carlo Vittorio, van Rooijen, Stefanus Johannes, Schreinemakers, Jennifer Marijke Janneke, Bojesen, Rasmus Dahlin, Gögenur, Ismail, van den Heuvel, Edwin R., Carli, Francesco, and Slooter, Gerrit Dirk more...

Published
2023
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18. Tailoring prehabilitation to address the multifactorial nature of functional capacity for surgery.

Author

Gillis, Chelsia, Coca‐Martinez, Miquel, and Santa Mina, Daniel

Subjects
*EVALUATION of medical care, *PREOPERATIVE care, *FUNCTIONAL status, *OPERATIVE surgery, *MATHEMATICAL models, *NUTRITION, *THEORY, *PREHABILITATION, *ENHANCED recovery after surgery protocol, *COMBINED modality therapy
Abstract

Mounting evidence suggests that recovery begins before the surgical incision. The presurgery phase of recovery, namely the preparation for optimal surgical recovery, can be reinforced with prehabilitation. Prehabilitation is the approach of enhancing the functional capacity of the individual to enable them to withstand a stressful event. With this narrative review, we apply the Wilson and Cleary conceptual model of patient outcomes to specify the complex and integrative relationship of health factors that limit functional capacity before surgery. To have the greatest impact on patient outcomes, prehabilitation programs require individualised and coordinated care from medical, nutritional, psychosocial and exercise services. Key points: 1.Many biological and physiological factors influence functional capacity.2.Some of the biological and physiological factors that limit function cannot be corrected with exercise alone.3.Prehabilitation programs that identify and address the root cause(s) for poor functional capacity with multimodal treatment may produce positive outcomes more consistently. [ABSTRACT FROM AUTHOR] more...

Published
2023
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20. Multimodal prehabilitation as a promising strategy for preventing physical deconditioning on the heart transplant waiting list

Author

Gimeno-Santos, Elena, primary, Coca-Martinez, Miquel, additional, Arguis, Maria J, additional, Navarro, Ricard, additional, Lopez-Hernandez, Antonio, additional, Castel, Maria A, additional, Romano, Barbara, additional, Lopez-Baamonde, Manuel, additional, Sandoval, Elena, additional, Farrero, Marta, additional, Sanz, Maria, additional, Bofill, Ana, additional, and Martinez-Palli, Graciela, additional more...

Published
2020
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21. Multimodal prehabilitation as strategy for reduction of postoperative complications after cardiac surgery: a randomised controlled trial protocol

Author

Coca-Martinez, Miquel, primary, Lopez-Hernandez, Antonio, additional, Montane-Muntane, Mar, additional, Arguis, Maria Jose, additional, Gimeno-Santos, Elena, additional, Navarro-Ripoll, Ricard, additional, Perdomo, Juan, additional, Lopez-Baamonde, Manuel, additional, Rios, Jose, additional, Moises, Jorge, additional, Sanz de la Garza, Maria, additional, Sandoval, Elena, additional, Romano, Barbara, additional, Sebio, Raquel, additional, Dana, Fernando, additional, and Martinez-Palli, Graciela, additional more...

Published
2020
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22. Prehabilitation: Who can benefit?

Author

Coca-Martinez, Miquel and Carli, Franco

Subjects
PREHABILITATION, PERIOPERATIVE care, MEDICAL personnel, QUALITY of life, EXERCISE therapy
Abstract

Prehabilitation is an intervention that occurs between cancer diagnosis and the start of an acute treatment. It involves physical, nutritional, and psychological assessments to establish a baseline functional level and provide targeted interventions to improve a person's health and prevent future impairments. Prehabilitation has been applied to surgical oncology and has shown positive results at improving functional capacity, reducing hospital stay, decreasing complications, and enhancing health-related quality of life. The importance of collaboration between various healthcare professionals and the implementation of multimodal interventions, including exercise training, nutrition optimization, and emotional support is discussed in this manuscript. The need for screening and assessment of conditions such as sarcopenia, frailty, or low functional status in order to identify patients who would benefit the most from prehabilitation is vital and should be a part of all prehabilitation programs. Exercise and nutrition play complementary roles in prehabilitation, enhancing anabolism and performance. However, in the presence of malnutrition and sarcopenia, exercise-related energy expenditure without sufficient protein intake can lead to muscle wasting and further deterioration of functional capacity, thus special emphasis on nutrition and protein intake should be made in these cases. Finally, the challenges and the need for a paradigm shift in perioperative care are discussed to effectively implement personalized prehabilitation programs. [ABSTRACT FROM AUTHOR] more...

Published
2024
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23. Multimodal Prehabilitation for Patients Undergoing Endovascular Aortic Aneurysm Repair Surgery: A Feasibility Study

Author

Coca-Martinez, Miquel, St-Pierre, Jade, Girsowicz, Elie, Doonan, Robert J., Obrand, Daniel I., Bayne, Jason P., Steinmetz, Oren K., Mackenzie, Kent S., Carli, Francesco, Martinez-Palli, Graciela, and Gill, Heather L. more...

Abstract

Background: Elective treatment options for aortic abdominal aneurysms include open repair or the less-invasive endovascular aortic aneurysm repair (EVAR). Recovery from EVAR is generally considered easier and faster than open repair. Despite this, EVAR remains a major procedure, and average return to preoperative quality of life is at least 3 months. The purpose of this study is to determine the safety and feasibility of multimodal prehabilitation, a multidisciplinary preoperative optimization intervention, in patients undergoing EVAR and its impact on perioperative functional capacity and quality of life.Methods: Candidates for EVAR with an infra-renal abdominal aortic aneurysm <7.5cm were invited to participate in a 6-week multimodal prehabilitation program that included (1) supervised and home-based exercise, (2) nutritional support, (3) psychosocial support, and (4) smoking cessation. Functional capacity and quality of life were assessed at baseline, before surgery and 6 weeks postoperatively. Recruitment rate, safety, and compliance were also assessed.Results: A total of 24 patients were included, 17 males (70%) and 7 females (30%). No adverse events occurred during the program. Compliance to each component of the program (median [Q1-Q3]) was 66% [67] for supervised training, 100% [67] for home-based training, and 100% [100] for nutrition. The multimodal prehabilitation program elicited a significant increase in functional capacity and quality of life preoperatively.Conclusion: Multimodal prehabilitation for patients awaiting EVAR is feasible and safe. Multimodal prehabilitation improves both functional capacity and quality of life preoperatively. Further research is needed to assess the impact of multimodal prehabilitation on postoperative quality of life and functional capacity.Clinical Impact Multimodal prehabilitation is safe and feasible in patients awaiting endovascular aneurysm repair. The importance of this finding is that multimodal prehabilitation can be safely delivered preoperatively in patients awaiting EVAR. Although further research is needed, multimodal prehabilitation seems to improve preoperative functional capacity and quality of life. This could have an impact for the future implementation of prehabilitation interventions in order to increase functional reserve and quality of life preoperatively so that this high-risk population can cope better with the surgical stress and return to their normal life faster postoperatively. more...

Published
2024
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24. Multimodal Prehabilitation for Patients Undergoing Endovascular Aortic Aneurysm Repair Surgery: A Feasibility Study.

Author

Coca-Martinez M, St-Pierre J, Girsowicz E, Doonan RJ, Obrand DI, Bayne JP, Steinmetz OK, Mackenzie KS, Carli F, Martinez-Palli G, and Gill HL

Abstract

Background: Elective treatment options for aortic abdominal aneurysms include open repair or the less-invasive endovascular aortic aneurysm repair (EVAR). Recovery from EVAR is generally considered easier and faster than open repair. Despite this, EVAR remains a major procedure, and average return to preoperative quality of life is at least 3 months. The purpose of this study is to determine the safety and feasibility of multimodal prehabilitation, a multidisciplinary preoperative optimization intervention, in patients undergoing EVAR and its impact on perioperative functional capacity and quality of life., Methods: Candidates for EVAR with an infra-renal abdominal aortic aneurysm <7.5cm were invited to participate in a 6-week multimodal prehabilitation program that included (1) supervised and home-based exercise, (2) nutritional support, (3) psychosocial support, and (4) smoking cessation. Functional capacity and quality of life were assessed at baseline, before surgery and 6 weeks postoperatively. Recruitment rate, safety, and compliance were also assessed., Results: A total of 24 patients were included, 17 males (70%) and 7 females (30%). No adverse events occurred during the program. Compliance to each component of the program (median [Q1-Q3]) was 66% [67] for supervised training, 100% [67] for home-based training, and 100% [100] for nutrition. The multimodal prehabilitation program elicited a significant increase in functional capacity and quality of life preoperatively., Conclusion: Multimodal prehabilitation for patients awaiting EVAR is feasible and safe. Multimodal prehabilitation improves both functional capacity and quality of life preoperatively. Further research is needed to assess the impact of multimodal prehabilitation on postoperative quality of life and functional capacity., Clinical Impact: Multimodal prehabilitation is safe and feasible in patients awaiting endovascular aneurysm repair. The importance of this finding is that multimodal prehabilitation can be safely delivered preoperatively in patients awaiting EVAR. Although further research is needed, multimodal prehabilitation seems to improve preoperative functional capacity and quality of life. This could have an impact for the future implementation of prehabilitation interventions in order to increase functional reserve and quality of life preoperatively so that this high-risk population can cope better with the surgical stress and return to their normal life faster postoperatively., Competing Interests: Declaration of Conflicting InterestsThe author(s) declared no potential conflicts of interest with respect to the research, authorship, and/or publication of this article. more...

Published
2023
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