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1. Recent safety and efficacy findings from a phase 1b/2 open-label combination study of ASP-1929 photoimmunotherapy with anti-PD-1 therapy in EGFR-expressing advanced head and neck squamous cell carcinoma (HNSCC).

Author

Cognetti, David M., primary, Curry, Joseph M., additional, Civantos, Francisco F, additional, Valentino, Joseph, additional, Agbaje-Williams, Mayowa, additional, Danesi, Hassan, additional, Dong, Haiying, additional, Larracas, Cristina, additional, Veresh, Bogdan, additional, Gillenwater, Ann M., additional, and Su, Shirley Y., additional

Published
2024
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2. Predictive capacity of immune‐related adverse events and cytokine profiling in neoadjuvant immune checkpoint inhibitor trials for head and neck squamous cell carcinoma

Author

Alnemri, Angela E., primary, Tekumalla, Sruti, additional, Moroco, Annie E., additional, Vathiotis, Ioannis, additional, Tuluc, Madalina, additional, Gargano, Stacey, additional, Zhan, Tingting, additional, Cognetti, David M., additional, Curry, Joseph M., additional, Argiris, Athanassios, additional, Linnenbach, Alban, additional, South, Andrew P., additional, Harshyne, Larry A., additional, Johnson, Jennifer M., additional, and Luginbuhl, Adam J., additional

Published
2024
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6. Proposal for standardized ultrasound analysis of the salivary glands: Part 1 submandibular gland

Author

Hoffman, Henry T., primary, Koch, Michael, additional, Witt, Robert Lee, additional, Ryan, William R., additional, Zenk, Johannes, additional, Katz, Philippe, additional, Rahmati, Rahmatullah, additional, Rassekh, Christopher, additional, Donato, Francisco, additional, McCulloch, Timothy M., additional, Joshi, Arjun S., additional, Chang, Jolie Lien, additional, Gillespie, M. Boyd, additional, Pichardo, Priscilla F. A., additional, Orloff, Lisa Ann, additional, Marcelino, Antoino, additional, Wenzel, Piper, additional, Cohen, David, additional, Fundakowski, Christopher E., additional, Cognetti, David M., additional, Walvekar, Rohan R., additional, Bertelli, Antonio, additional, Quon, Harry, additional, Anderson, Carryn, additional, Policeni, Bruno, additional, and Siegel, Gordy, additional

Published
2024
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7. Effect of preoperative programmed death‐1 or programmed death ligand‐1 immune check point inhibition on complications after surgery for primary head and neck cancer

Author

Philips, Ramez, primary, Alnemri, Angela, additional, Amin, Dev, additional, Patel, Jena, additional, Topf, Michael C., additional, Johnson, Jennifer M., additional, BarAd, Voichita, additional, Axelrod, Rita, additional, Argiris, Athanassios, additional, Fundakowski, Christopher, additional, Luginbuhl, Adam J., additional, Cognetti, David M., additional, and Curry, Joseph M., additional

Published
2023
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8. List of Contributors

Author

Abboud, Olivier, primary, Abdullah, Victor James, additional, Ahmad, Zahoor, additional, Al-Qurayshi, Zaid, additional, Athwal, Harleen K., additional, Bacon, Alfred E., additional, Balzer, Bonnie Lei, additional, Bell, Diana, additional, Bradley, Patrick James, additional, Brito-Zerón, Pilar, additional, Cernea, Claudio R., additional, Chan, Jason YK, additional, Chaplin, John M., additional, Cheong, Crystal Shuk Jin, additional, Chien, Chih-Yen, additional, Chossegros, Cyrille, additional, Chuang, Hui-Ching, additional, Clarke, Raymond William, additional, Cognetti, David M., additional, Dam, Hung, additional, Deschler, Daniel, additional, Dias, Fernando L., additional, Do, Kevin Oshiro, additional, Dulguerov, Pavel, additional, Eisele, David W., additional, Fagan, Johannes J., additional, Farach-Carson, Mary C., additional, Farina, Davide, additional, Faure, Frederic, additional, Ferrarotto, Renata, additional, Flores-Chavez, Alejandra, additional, Foletti, Jean Marc, additional, Freiser, Monika E., additional, Gandhi, Arpit, additional, Gasalberti, David, additional, Geisthoff, Urban, additional, Gillespie, M. Boyd, additional, Graillon, Nicolas, additional, Hammon, Rebecca J., additional, Hao, Chung-Yu, additional, Hao, Sheng-Po, additional, Harrington, Daniel A., additional, Harrison, John D., additional, Hoffman, Henry T., additional, Iaia, Alberto, additional, Ihrler, Stephan, additional, Iro, Heinrich, additional, Irvine, Robert A., additional, Kahane, Jacob, additional, Zanoni, Daniella Karassawa, additional, Kim, Kwang Hyun, additional, Klein, Hila, additional, Koch, Michael, additional, Lai, Nelson Kwong Lun, additional, Lancini, Davide, additional, Larian, Babak, additional, Lau, Thomas Kwan Hang, additional, Laughlin, Brady, additional, Le Roux, Marc-Kevin, additional, Lee, Doh Young, additional, Lee Kun Min, Mimi, additional, Li, Hok Nam, additional, Lima, Roberto A., additional, Loh, Thomas K.S., additional, Loh, Woei-Shyang, additional, Lombaert, Isabelle M.A., additional, Lombardi, Davide, additional, Lopez, Jean-Michel, additional, Mantsopoulos, Konstantinos, additional, Marchal, Francis, additional, McGurk, Mark, additional, Meyeroff, Joshua H., additional, Morton, Randall P., additional, Myers, Eugene Nicholas, additional, Nahlieli, Oded, additional, Ng, Siu-Kwan, additional, Nicolai, Piero, additional, O'Malley, Bert W., additional, Palhazi, Peter, additional, Park, SuJung, additional, Pasche, Philippe, additional, Patel, Snehal G., additional, Peterson, Joseph D., additional, Polselli, Roberto, additional, Pouzoulet, Pauline, additional, Pradhan-Bhatt, Swati, additional, Raben, Adam, additional, Ramos-Casals, Manuel, additional, Rassekh, Christopher H., additional, Reeve, Nathaniel, additional, Retamozo, Soledad, additional, Santos, Jorge Rosa, additional, Saban, Yves, additional, Sagiv, Doron, additional, Samant, Sumit, additional, Schaitkin, Barry M., additional, Sözen, Tevfik, additional, Srinivasan, Padma Pradeepa, additional, Strenger, Tobias, additional, Su, Shirley Y., additional, Tae, Kyung, additional, Talmi, Yoav P., additional, Tomasoni, Michele, additional, Poorten, Vincent Vander, additional, Walvekar, Rohan R., additional, Wang, Jennifer R., additional, Wang, Robert C., additional, Weber, Randal S., additional, Weinstein, Gregory S., additional, Wong, Eddy WY, additional, Wong, Priscilla Ching-han, additional, Zbären, Peter, additional, Zenga, Joseph, additional, and Zenk, Johannes, additional

Published
2021
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11. Effect of preoperative programmed death‐1 or programmed death ligand‐1 immune check point inhibition on complications after surgery for primary head and neck cancer.

Author

Philips, Ramez, Alnemri, Angela, Amin, Dev, Patel, Jena, Topf, Michael C., Johnson, Jennifer M., BarAd, Voichita, Axelrod, Rita, Argiris, Athanassios, Fundakowski, Christopher, Luginbuhl, Adam J., Cognetti, David M., and Curry, Joseph M.

Subjects
FREE flaps, SURGICAL complications, HEAD & neck cancer, IMMUNE checkpoint inhibitors, SURGICAL robots, PROPENSITY score matching
Abstract

Background: There is sparse literature on the effect of preoperative immunotherapy on complications after surgery for primary head and neck squamous cell carcinoma (HNSCC). The objectives are to compare complication rates in patients receiving surgery with and without neoadjuvant immune checkpoint inhibitors (nICI) for primary HNSCC and to evaluate factors associated with increased odds of surgical complications. Methods: A retrospective review of patients who underwent ablation and free flap reconstruction or transoral robotic surgery (TORS) for primary HNSCC between 2017–2021 was conducted. Complications were compared between patients who underwent surgery with or without nICI before and after propensity score matching. Regression analysis to estimate odds ratios was performed. Results: A total of 463 patients met inclusion criteria. Free flap reconstruction constituted 28.9% of patients and TORS constituted 71.1% of patients. nICI was administered in 83 of 463 (17.9%) patients. There was no statistically significant difference in surgical, medical, or overall complications between patients receiving surgery with or without nICI. In the unmatched cohort, multivariable model identified non‐White race, former/current smoking history, free flap surgery, and perineural invasion as factors significantly associated with increased complications. In the matched cohort, multivariable model identified advanced age and free flap surgery as factors significantly associated with increased complications. Plain Language Summary: It is safe to give immunotherapy before major surgery in patients who have head and neck cancer.Advanced age, non‐White race, current/former smoking, free flap surgery, and perineural invasion may be associated with increased the odds of surgical complications. In this study, neoadjuvant immune checkpoint inhibitors (nICI) did not increase the risk of overall complications after adjusting for important confounders. Definitive surgery can be conducted safely after nICI. [ABSTRACT FROM AUTHOR]

Published
2024
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12. Nivolumab and ipilimumab in combination with radiotherapy in patients with high-risk locally advanced squamous cell carcinoma of the head and neck

Author

Johnson, Jennifer M, primary, Vathiotis, Ioannis A, additional, Harshyne, Larry A, additional, Ali, Ayesha, additional, Bar Ad, Voichita, additional, Axelrod, Rita, additional, Lorber, Emily, additional, Curry, Joseph, additional, Cognetti, David M, additional, Luginbuhl, Adam J, additional, Tuluc, Madalina, additional, Keith, Scott, additional, Mahoney, Mỹ G, additional, and Argiris, Athanassios, additional

Published
2023
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15. Oncologic Safety of Close Margins in Patients With Low- to Intermediate-Grade Major Salivary Gland Carcinoma

Author

Sajisevi, Mirabelle, Nguyen, Kenny, Callas, Peter, Holcomb, Andrew J., Vural, Emre, Davis, Kyle P., Thomas, Carissa M., Plonowska-Hirschfeld, Karolina A., Stein, John S., Eskander, Antoine, Kakarala, Kiran, Enepekides, Danny J., Hier, Michael P., Ryan, William R., Asarkar, Ameya A., Aulet, Ricardo, Bell, Rebecca K., Blasco, Michael A., Bowmaster, Vanessa B., Burruss, Clayton P., Chung, Jeffson, Chan, Kimberly, Chang, Brent A., Coffey, Charles S., Cognetti, David M., Cooper, Dylan J., Cordero, Joehassin, Donovan, John, Du, Yue (Jennifer), Dundar, Yusuf, Dedivitis, Rogerio A., Edwards, Heather A., Erovic, Boban M., Feinberg, Philip A., Garvey, Emily A., Goldstein, David P., Goodman, Joseph F., Goulart, Rafael N., Goyal, Neerav, Grasl, Stefan, Giurintano, Jonathan P., Gupta, Nikita, Habib, Andy M., Hackman, Trevor G., Hara, Jared H., Henson, Christina, Hinni, Michael L., Hua, Nadia, Johnson-Obaseki, Stephanie, Juloori, Aditya, Kalman, Noah S., Kejner, Alexandra E., Khaja, Sobia F., Ku, Jamie A., Lambert, Arnaud, Luu, Bao K., Magliocca, Kelly R., dos Santos, Luiz R. Medina, Michael, Cara, Miles, Brett A., de Melo, Giulianno Molina, Moore, Michael G., Morand, Gregoire B., Moura, Kauê, Mukdad, Laith, Noroozi, Hesameddin, Patel, Rusha, Paydarfar, Joseph A., Sadeghi, Nader, Savaria, Fabrice N., Schmitt, Nicole C., Shapiro, Justin, Shaver, Timothy B., Stoeckli, Sandro J., St. John, Maie, Stokes, William Alvo, Sulibhavi, Anita, Tasoulas, Jason, Vendra, Varun, Vinh, Daniel B., Virgen, Celina G., Wooten, Christian, Woody, Neil M., and Young, Geoffrey D.

Abstract

IMPORTANCE: Postoperative radiation therapy for close surgical margins in low- to intermediate-grade salivary carcinomas lacks multi-institutional supportive evidence. OBJECTIVE: To evaluate the oncologic outcomes for low- and intermediate-grade salivary carcinomas with close and positive margins. DESIGN, SETTING, AND PARTICIPANTS: The American Head and Neck Society Salivary Gland Section conducted a retrospective cohort study from 2010 to 2019 at 41 centers. Margins were classified as R0 (negative), R1 (microscopically positive), or R2 (macroscopically positive). R0 margins were subclassified into clear (>1 mm) or close (≤1 mm). Data analysis was performed from June to October 2023. MAIN OUTCOMES AND MEASURES: Main outcomes were risk factors for local recurrence. RESULTS: A total of 865 patients (median [IQR] age at surgery, 56 [43-66] years; 553 female individuals [64%] and 312 male individuals [36%]) were included. Of these, 801 (93%) had parotid carcinoma and 64 (7%) had submandibular gland carcinoma, and 748 (86%) had low-grade tumors and 117 (14%) had intermediate-grade tumors, with the following surgical margins: R0 in 673 (78%), R1 in 168 (19%), and R2 in 24 (3%). Close margins were found in 395 of 499 patients with R0 margins (79%), for whom margin distances were measured. A total of 305 patients (35%) underwent postoperative radiation therapy. Of all 865 patients, 35 (4%) had local recurrence with a median (IQR) follow-up of 35.3 (13.9-59.1) months. In patients with close margins as the sole risk factor for recurrence, the local recurrence rates were similar between those who underwent postoperative radiation therapy (0 of 46) or observation (4 of 165 [2%]). Patients with clear margins (n = 104) had no recurrences. The local recurrence rate in patients with R1 or R2 margins was better in those irradiated (2 of 128 [2%]) compared to observed (13 of 64 [20%]) (hazard ratio [HR], 0.05; 95% CI, 0.01-0.24). Multivariable analysis for local recurrence found the following independent factors: age at diagnosis (HR for a 10-year increase in age, 1.33; 95% CI, 1.06-1.67), R1 vs R0 (HR, 5.21; 95% CI, 2.58-10.54), lymphovascular invasion (HR, 4.47; 95% CI, 1.43-13.99), and postoperative radiation therapy (HR, 0.10; 95% CI, 0.04-0.29). The 3-year local recurrence-free survivals for the study population were 96% vs 97% in the close margin group. CONCLUSIONS AND RELEVANCE: In this cohort study of patients with low- and intermediate-grade major salivary gland carcinoma, postoperative radiation therapy for positive margins was associated with decreased risk of local recurrence. In isolation from other risk factors for local recurrence, select patients with close surgical margins (≤1 mm) may safely be considered for observation.

Published
2024
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17. Supplementary Figure from Tadalafil Enhances Immune Signatures in Response to Neoadjuvant Nivolumab in Resectable Head and Neck Squamous Cell Carcinoma

Author

Luginbuhl, Adam J., primary, Johnson, Jennifer M., primary, Harshyne, Larry A., primary, Linnenbach, Alban J., primary, Shukla, Sanket K., primary, Alnemri, Angela, primary, Kumar, Gaurav, primary, Cognetti, David M., primary, Curry, Joseph M., primary, Kotlov, Nikita, primary, Antysheva, Zoya, primary, Degryse, Sandrine, primary, Mannion, Kyle, primary, Gibson, Michael K., primary, Netterville, James, primary, Brown, Brandee, primary, Axelrod, Rita, primary, Zinner, Ralph, primary, Tuluc, Madalina, primary, Gargano, Stacey, primary, Leiby, Benjamin E., primary, Shimada, Ayako, primary, Mahoney, My G., primary, Martinez-Outschoorn, Ubaldo, primary, Rodeck, Ulrich, primary, Kim, Young J., primary, South, Andrew P., primary, and Argiris, Athanassios, primary

Published
2023
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19. IL‐8 correlates with nonresponse to neoadjuvant nivolumab in HPV positive HNSCC via a potential extracellular vesicle miR‐146a mediated mechanism.

Author

Hill, Brianna L., Calder, Alyssa N., Flemming, Joseph P., Guo, Yiyang, Gilmore, Sydney L., Trofa, Melissa A., Daniels, Sean K., Nielsen, Torbjoern N., Gleason, Laura K., Antysheva, Zoya, Demina, Ksenia, Kotlov, Nikita, Davitt, Christopher J. H., Cognetti, David M., Prendergast, George C., Snook, Adam E., Johnson, Jennifer M., Kumar, Gaurav, Linnenbach, Alban J., and Martinez‐Outschoorn, Ubaldo

Published
2023
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21. Effects of Prior Tracheostomy on Total Laryngectomy Outcomes

Author

Sussman, Sarah, primary, Philips, Ramez, additional, Renslo, Bryan, additional, Givens, Alyssa, additional, Swendseid, Brian, additional, Tassone, Patrick, additional, Goldman, Richard A., additional, Curry, Joseph M., additional, Cognetti, David M., additional, and Luginbuhl, Adam J., additional

Published
2022
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25. Effects of Prior Tracheostomy on Total Laryngectomy Outcomes.

Author

Sussman, Sarah, Philips, Ramez, Renslo, Bryan, Givens, Alyssa, Swendseid, Brian, Tassone, Patrick, Goldman, Richard A., Curry, Joseph M., Cognetti, David M., and Luginbuhl, Adam J.

Abstract

Objective: To assess whether preoperative tracheostomy (PreOT) increases risk of complications after total laryngectomy (TL) and to determine if timing of tracheostomy creation is associated with an increased risk. Study Design: Retrospective cohort study. Setting: Tertiary care hospital between 2007 and 2020. Methods: Inclusion criteria were patients who underwent primary or salvage TL for oncologic treatment. Dependent variables of interest included surgical complications, such as wound dehiscence, infection, hematoma, complete flap failure, fistula formation, and stoma stenosis, as well as medical complications. Categorical variables were compared with chi‐square test or Fisher exact test, and continuous variables were compared with an independent t test. Multivariable regression was conducted to assess predictors of complications after laryngectomy. Results: A total of 306 patients were included. Primary TL was performed in 161 (53%) patients and salvage in 145 (47%) patients. Of the patients undergoing primary laryngectomy, 105 (65%) received a PreOT. Of the patients undergoing salvage laryngectomy, 86 (59%) received a PreOT. In both primary and salvage cases, there was no association between PreOT and surgical or medical complications. Additionally, there was no significant association between timing of tracheostomy and surgical complications. On multivariable analysis, the presence of a PreOT was not associated with surgical complications. In salvage cases, those with a PreOT had a significantly longer average length of stay than those without a PreOT (12 vs 9 days, P =.008). Conclusion: PreOT in patients undergoing primary and salvage laryngectomies was not associated with surgical or medical complications postlaryngectomy. Timing of tracheostomy in relation to laryngectomy was not found to adversely affect clinical outcomes. [ABSTRACT FROM AUTHOR]

Published
2023
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26. [99mTc]Tilmanocept Accurately Detects Sentinel Lymph Nodes and Predicts Node Pathology Status in Patients with Oral Squamous Cell Carcinoma of the Head and Neck: Results of a Phase III Multi-institutional Trial

Author

Agrawal, Amit, Civantos, Francisco J., Brumund, Kevin T., Chepeha, Douglas B., Hall, Nathan C., Carroll, William R., Smith, Russell B., Zitsch, Robert P., Lee, Walter T., Shnayder, Yelizaveta, Cognetti, David M., Pitman, Karen T., King, Dennis W., Christman, Lori A., and Lai, Stephen Y.

Published
2015
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28. Analysis of cost and outcomes in bony versus soft tissue midface free flap reconstruction

Author

Alnemri, Angela, primary, Philips, Ramez, additional, Sussman, Sarah, additional, Xu, Vivian, additional, Givens, Alyssa, additional, Patel, Anjali, additional, Swendseid, Brian, additional, Agarwal, Aarti, additional, Keith, Scott, additional, Shimada, Ayako, additional, Selman, Yamil, additional, Cognetti, David M., additional, Heffelfinger, Ryan, additional, Goldman, Richard, additional, Luginbuhl, Adam J., additional, Wax, Mark K., additional, Sweeny, Larissa, additional, and Curry, Joseph M., additional

Published
2022
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30. An Updated Patient‐Centered Sialadenitis Instrument: The Obstructive Salivary Problem Impact Test (SPIT).

Author

Gulati, Arushi, Cognetti, David M., Cohen, David S., Ogden, M. Allison, Schaitkin, Barry M., Walvekar, Rohan R., Ryan, William R., and Chang, Jolie L.

Abstract

Objective: The Chronic Obstructive Sialadenitis Symptoms questionnaire (COSS) was created to assess chronic sialadenitis symptoms and treatment response, but its development lacked patient input and validation. We analyzed COSS responses and feedback from sialadenitis patients and physician experts to create the novel obstructive Salivary Problem Impact Test (SPIT), a new standardized measure of sialadenitis‐associated symptoms. Methods: We analyzed COSS responses via exploratory factor analysis (EFA) to identify essential symptom domains and reduce overlap in questions. Sialadenitis patients evaluated the significance of index symptoms identified from the literature review. Expert physicians rated symptom relevance in clinical assessment. An updated questionnaire (SPIT) was piloted with both patient and expert interviews to optimize structure and readability. The SPIT was assessed for internal consistency, construct validity, and test–retest stability. Results: EFA of 310 COSS responses demonstrated 3 main symptom domains (functional impact, pain, swelling) that explained 58.4% of response variance. Results were not statistically different when collapsing from 11 to 5 question response options. Experts (n = 5) ranked gland swelling, mealtime pain, and foul taste as most clinically important, while patients (n = 12) ranked swelling, non‐mealtime pain, and difficulty eating as most bothersome. Most patients experienced sialadenitis‐related functional or psychosocial impairment. Following interviews for question refinement, a 25‐question survey was finalized. SPIT responses from 50 sialadenitis patients demonstrated internal consistency (Cronbach's alpha = 0.96), 14‐day stability (p < 0.001), and agreement with Oral Health Impact Profile‐14 scores (p < 0.0001). Conclusions: We developed the SPIT instrument to improve usability and content validity in chronic sialadenitis evaluation. The psychometric assessment demonstrated high construct validity and test–retest reliability. Further work will assess longitudinal changes with treatment. Level of Evidence: 4 Laryngoscope, 133:539–546, 2023 [ABSTRACT FROM AUTHOR]

Published
2023
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31. Evaluating YouTube videos on sialendoscopy as an educational resource for patients.

Author

Campbell, Daniel J., Xiao, Kevin, Mastrolonardo, Eric, and Cognetti, David M.

Subjects
VIDEOS, EDUCATIONAL films, EDUCATIONAL resources, ACADEMIC medical centers, OPERATING rooms
Abstract

Objectives: Patients are increasingly relying on YouTube for health information. We objectively evaluated the quality and comprehensiveness of sialendoscopy YouTube videos available to patients. We further investigated the relationship between video content and video popularity. Methods: We identified 150 videos using the search term "sialendoscopy." Videos were excluded if they were lectures for medical professionals, operating room (OR) recordings, unrelated, non‐English, or non‐audio. Video quality and comprehensiveness were evaluated using modified DISCERN criterion (range: 5–25) and novel sialendoscopy criterion (NSC, range: 0–7), respectively. Secondary outcomes included standard video metrics and Video Power Index to measure popularity. Videos were classified binarily by uploader type as from an academic medical center or from other sources. Results: Twenty‐two (14.7%) of 150 videos were included for review, with 7 (31.8%) uploaded from academic medical institutions. One hundred‐nine (72.7%) videos were excluded as lectures for medical professionals or OR recordings. Overall mean modified DISCERN (13.45 ± 3.42) and NSC (3.05 ± 0.96) scores were low; however, videos uploaded by academic medical institutions were significantly more comprehensive (NSC mean difference = 0.98, 95% CI: 0.16–1.80, p =.02). There were no significant correlations between video popularity and objective measures of quality or comprehensiveness. Conclusions: This study highlights the paucity and low quality of sialendoscopy videos for patients. More popular videos are not higher quality, and most videos are targeted more toward physicians rather than patients. As YouTube becomes increasingly used by patients, there is opportunity for otolaryngologists to produce more informative videos for patients while implementing targeted strategies to increase viewership. Level of Evidence: NA. [ABSTRACT FROM AUTHOR]

Published
2023
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34. Tadalafil Enhances Immune Signatures in Response to Neoadjuvant Nivolumab in Resectable Head and Neck Squamous Cell Carcinoma

Author

Luginbuhl, Adam J., primary, Johnson, Jennifer M., additional, Harshyne, Larry A., additional, Linnenbach, Alban J., additional, Shukla, Sanket K., additional, Alnemri, Angela, additional, Kumar, Gaurav, additional, Cognetti, David M., additional, Curry, Joseph M., additional, Kotlov, Nikita, additional, Antysheva, Zoya, additional, Degryse, Sandrine, additional, Mannion, Kyle, additional, Gibson, Michael K., additional, Netterville, James, additional, Brown, Brandee, additional, Axelrod, Rita, additional, Zinner, Ralph, additional, Tuluc, Madalina, additional, Gargano, Stacey, additional, Leiby, Benjamin E., additional, Shimada, Ayako, additional, Mahoney, My G., additional, Martinez-Outschoorn, Ubaldo, additional, Rodeck, Ulrich, additional, Kim, Young J., additional, South, Andrew P., additional, and Argiris, Athanassios, additional

Published
2021
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35. Phase 1/2a, open‐label, multicenter study ofRM‐1929 photoimmunotherapy in patients with locoregional, recurrent head and neck squamous cell carcinoma

Author

Cognetti, David M., primary, Johnson, Jennifer M., additional, Curry, Joseph M., additional, Kochuparambil, Samith T., additional, McDonald, Darren, additional, Mott, Frank, additional, Fidler, Mary J., additional, Stenson, Kerstin, additional, Vasan, Nilesh R., additional, Razaq, Mohammad A., additional, Campana, John, additional, Ha, Patrick, additional, Mann, Grace, additional, Ishida, Kosuke, additional, Garcia‐Guzman, Miguel, additional, Biel, Merrill, additional, and Gillenwater, Ann M., additional

Published
2021
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38. Using ultrasonic preoperative thyroid volume to determine incision length for minimally invasive thyroid surgery

Author

Daly, Austin P., Romanelli-Gobbi, Massi, Miller, Jeffrey L., Rosen, David, Cognetti, David M., and Pribitkin, Edmund A.

Subjects
Minimally invasive surgery -- Methods, Diagnosis, Ultrasonic -- Methods, Preoperative care -- Methods, Thyroidectomy -- Methods, Health
Abstract

Abstract The determination of the volume of a diseased thyroid lobe or an entire gland by preoperative ultrasonography may enable surgeons to select candidates for a minimally invasive approach to [...]

Published
2015

39. Pathologic and radiographic responses in a window of opportunity for durvalumab plus metformin trial for squamous cell carcinoma of the head and neck (HNSCC).

Author

Curry, Joseph M., primary, Alnemri, Angela, additional, Swendseid, Brian, additional, Nwagu, Uche, additional, Cognetti, David M., additional, Bar-Ad, Voichita C, additional, Luginbuhl, Adam, additional, Axelrod, Rita Susan, additional, Whitaker-Menezes, Diana, additional, Harshyne, Larry, additional, South, Andrew, additional, Mahoney, My G., additional, Linnenbach, Alban, additional, Argiris, Athanassios, additional, Rodek, Ulrich, additional, Martinez-Outschoorn, Ubaldo, additional, and Johnson, Jennifer Maria, additional

Published
2021
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40. Oncologic outcomes of human papillomavirus–associated oropharynx carcinoma treated with surgery alone: A 12‐institution study of 344 patients

Author

Ryan, William R., primary, Xu, Mary J., additional, Ochoa, Edgar, additional, Plonowska‐Hirschfeld, Karolina A., additional, Zebolsky, Aaron L., additional, Ha, Patrick K., additional, Bewley, Arnaud F., additional, Mallen‐St. Clair, Jonathan, additional, Joshi, Arjun S., additional, Coffey, Charles S., additional, Faraji, Farhoud, additional, MacDonald, Bridget V., additional, Houlton, Jeffrey J., additional, Gobillot, Theodore A., additional, Curry, Joseph M., additional, Philips, Ramez, additional, Hackman, Trevor G., additional, Richmon, Jeremy D., additional, Holcomb, Andrew J., additional, Coughlin, Andrew M., additional, Panwar, Aru, additional, Smith, Russell B., additional, Herberg, Matthew E., additional, Fakhry, Carole, additional, and Cognetti, David M., additional

Published
2021
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47. Discordant Responses Between Primary Head and Neck Tumors and Nodal Metastases Treated With Neoadjuvant Nivolumab: Correlation of Radiographic and Pathologic Treatment Effect

Author

Merlino, Dante J., primary, Johnson, Jennifer M., additional, Tuluc, Madalina, additional, Gargano, Stacey, additional, Stapp, Robert, additional, Harshyne, Larry, additional, Leiby, Benjamin E., additional, Flanders, Adam, additional, Zinner, Ralph, additional, Axelrod, Rita, additional, Curry, Joseph, additional, Cognetti, David M., additional, Mannion, Kyle, additional, Kim, Young J., additional, Rodeck, Ulrich, additional, Argiris, Athanassios, additional, and Luginbuhl, Adam J., additional

Published
2020
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48. Tracheostomy During the COVID-19 Pandemic: Comparison of International Perioperative Care Protocols and Practices in 26 Countries

Author

Bier-Laning, Carol, primary, Cramer, John D., additional, Roy, Soham, additional, Palmieri, Patrick A., additional, Amin, Ayman, additional, Añon, José Manuel, additional, Bonilla-Asalde, Cesar A., additional, Bradley, Patrick J., additional, Chaturvedi, Pankaj, additional, Cognetti, David M., additional, Dias, Fernando, additional, Di Stadio, Arianna, additional, Fagan, Johannes J., additional, Feller-Kopman, David J., additional, Hao, Sheng-Po, additional, Kim, Kwang Hyun, additional, Koivunen, Petri, additional, Loh, Woei Shyang, additional, Mansour, Jobran, additional, Naunheim, Matthew R., additional, Schultz, Marcus J., additional, Shang, You, additional, Sirjani, Davud B., additional, St. John, Maie A., additional, Tay, Joshua K., additional, Vergez, Sébastien, additional, Weinreich, Heather M., additional, Wong, Eddy W. Y., additional, Zenk, Johannes, additional, Rassekh, Christopher H., additional, and Brenner, Michael J., additional

Published
2020
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