Search

Your search keyword '"Cohen, Arnon D"' showing total 933 results
Start Over Author "Cohen, Arnon D"
933 results on '"Cohen, Arnon D"'

10. Anxiety and depression predispose individuals to an autoimmune bullous diseases- bullous pemphigoid: A large-scale population-based cohort study

Author

Kridin, Khalaf, Hundt, Jennifer E., Ludwig, Ralf J., Schonmann, Yochai, and Cohen, Arnon D.

Subjects
Comorbidity -- Risk factors, Bullous pemphigoid -- Complications and side effects, Depression, Mental -- Risk factors, Anxiety -- Risk factors, Psychology and mental health
Abstract

The association of bullous pemphigoid (BP) with anxiety and anxiety-depression comorbidity is yet to be established. We aimed to evaluate the bidirectional association of BP with anxiety, depression, and anxiety-depression comorbidity, and to delineate the epidemiological features of patients with BP and the aforementioned psychiatric comorbidities. A population-based cohort study was performed to assess the risk of anxiety, depression, and anxiety-depression comorbidity among patients with BP (n = 3924) relative to age-, sex- and ethnicity-matched control subjects (n = 19,280). A case-control design was additionally adopted to estimate the odds of BP in individuals with a preexisting diagnosis of these three psychiatric conditions. Adjusted hazard ratios (HRs) and adjusted odds ratios (ORs) were estimated by Cox regression and logistic regression, respectively. A history of anxiety (OR, 1.17; 95% CI, 1.04-1.31), depression (OR, 1.26; 95% CI, 1.15-1.38), and anxiety-depression comorbidity (OR, 1.19; 95% CI, 1.04-1.35) was associated with subsequent development of BP. In the cohort study design, patients with BP were found to be at an increased overall risk of depression (HR, 1.17; 95% CI, 1.01-1.35), while female BP patients had an increased risk of depression (HR, 1.19; 95% CI, 1.00-1.42) and anxiety (HR, 1.29; 95% CI, 1.00-1.67). Patients with comorbid BP and depression exhibited a 19% increased all-cause mortality rate (HR, 1.19; 95% CI, 1.08-1.31), whereas patients with BP and anxiety-depression comorbidity were less adherent to long-term topical corticosteroid treatment and less frequently managed by adjuvant agents. In conclusion, a history of anxiety, depression, and anxiety-depression comorbidity predisposes individuals to BP, whereas patients with BP are at an increased risk of depression. Clinicians managing patients with anxiety and depression should take the increased risk of BP into consideration, and patients with BP should be monitored for depression., Author(s): Khalaf Kridin [sup.1] [sup.2] , Jennifer E. Hundt [sup.1] , Ralf J. Ludwig [sup.1] , Yochai Schonmann [sup.3] , Arnon D. Cohen [sup.3] [sup.4] Author Affiliations: (1) grid.4562.5, 0000 [...]

Published
2022
Full Text
View/download PDF

22. Racial/ethnic and socioeconomic disparities in colorectal cancer screening in a large organization with universal insurance before and during the coronavirus disease 2019 pandemic.

Author

Levi, Zohar, Abu-Frecha, Naim, Comanesther, Doron, Backenstein, Tania, Cohen, Arnon D, Eizenstein, Sapir, Flugelman, Anath, and Weinstein, Orly

Subjects
JEWS, EARLY detection of cancer, SOCIOECONOMIC disparities in health, HEALTH insurance, HEALTH policy, EQUALITY, COLORECTAL cancer, RETROSPECTIVE studies, DESCRIPTIVE statistics, RACE, FECAL occult blood tests, ODDS ratio, MEDICAL records, ACQUISITION of data, ARABS, ORTHODOX Jews, HEALTH equity, HEALTH maintenance organizations, CONFIDENCE intervals, COVID-19 pandemic, COLONOSCOPY, SOCIAL classes, TIME
Abstract

Objectives: Israel is regarded as a country with a developed economy and a moderate income inequality index. In this population-based study, we aimed to measure the inequalities in colorectal cancer screening within Clalit Health, an organization with universal insurance, before and during the coronavirus disease 2019 pandemic. Setting: Retrospective analysis within Clalit Health Services, Israel. Methods: We evaluated the rate of being up to date with screening (having a colonoscopy within 10 years or a fecal occult blood test within 1 year) and the colonoscopy completion rate (having a colonoscopy within 6 months of a positive fecal occult blood test) among subjects aged 50–75 in 2019–2021. Results: In 2019, out of 918,135 subjects, 61.3% were up to date with screening; high socioeconomic status: 65.9% (referent), medium-socioeconomic status: 60.1% (odds ratio 0.81, 95% confidence interval 0.80–0.82), low-socioeconomic status: 59.0% (odds ratio 0.75, 95% confidence interval 0.74–0.75); Jews: 61.9% (referent), Arabs: 59.7% (odds ratio 0.91, 95% confidence interval 0.90–0.92), Ultraorthodox-Jews: 51.7% (odds ratio 0.77, 95% confidence interval 0.75–0.78). Out of 21,308 with a positive fecal occult blood test, the colonoscopy completion rate was 51.8%; high-socioeconomic status: 59.8% (referent), medium-socioeconomic status: 54.1% (odds ratio 0.79, 95% confidence interval 0.73–0.86), low-socioeconomic status: 45.5% (odds ratio 0.60, 95% confidence interval 0.56–0.65); Jews: 54.7% (referent), Ultraorthodox-Jews: 51.4% (odds ratio 0.91, 95% confidence interval 0.90–0.92), Arabs: 44.7% (odds ratio 0.77, 95% confidence interval 0.75–0.78). In 2020–2021, there was a slight drop in the rate of being up to date with screening, while most of the discrepancies were kept or slightly increased with time. Conclusions: We report significant inequalities in colorectal cancer screening before and during the coronavirus disease 2019 pandemic in Israel, despite a declared policy of equality and universal insurance. [ABSTRACT FROM AUTHOR]

Published
2024
Full Text
View/download PDF

Catalog

Books, media, physical & digital resources
See catalog results