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Purpose: Impending compartment syndrome is a common event following closed tibia fractures, which can progress to sinister compartment syndrome. Fasciotomy is the only definitive treatment available, though it has its own drawbacks and complications. Medical management at present consists of limb elevation and adequate hydration. This study aims at determining whether intravenous administration of Mannitol reduced the intracompartmental pressure in patients with closed tibial fractures. Methods: This is a double blinded, randomized control trial done in a single tertiary care center in India. Forty-five patients were recruited between February 2012 and October 2012. Forty patients who presented to the emergency department with isolated, closed, high velocity, and proximal 2/3 tibia fractures were included in this study. Patients with contraindication to Mannitol were excluded. They were allocated into 2 groups by the investigator using computer generated randomization. The pressure in the anterior compartment of the leg was measured with a handheld Stryker pressure monitor. Then either 20% Mannitol or 0.9% normal saline as given intravenously in a blinded manner, based on the randomization. The intracompartmental pressure was measured at 0, 1 and 3 h after the infusion. The participant, investigator and statistician were masked to the group assessment. Results: There was no difference in intracompartmental pressures at 1 or 3 h, between the groups. However, in patients with the baseline of compartmental pressures ≥30 mmHg, Mannitol showed a marked reduction in pressure of 8.5 mmHg at 1 h compared to almost no change in pressure in the saline group. There were no adverse events with the use of Mannitol. Conclusions: This preliminary study appears to show that Mannitol is useful in the management of the increased compartment pressure. The limitations of this study were that it only involved a small group of patients and the baseline pressures in both the groups were not comparable. More studies are required before the use of Mannitol as a standard of care in the management of compartment syndrome can be established.

Purpose: Impending compartment syndrome is a common event following closed tibia fractures, which can progress to sinister compartment syndrome. Fasciotomy is the only definitive treatment available, though it has its own drawbacks and complications. Medical management at present consists of limb elevation and adequate hydration. This study aims at determining whether intravenous administration of Mannitol reduced the intracompartmental pressure in patients with closed tibial fractures.Methods: This is a double blinded, randomized control trial done in a single tertiary care center in India. Forty-five patients were recruited between February 2012 and October 2012. Forty patients who presented to the emergency department with isolated, closed, high velocity, and proximal 2/3 tibia fractures were included in this study. Patients with contraindication to Mannitol were excluded. They were allocated into 2 groups by the investigator using computer generated randomization. The pressure in the anterior compartment of the leg was measured with a handheld Stryker pressure monitor. Then either 20% Mannitol or 0.9% normal saline as given intravenously in a blinded manner, based on the randomization. The intracompartmental pressure was measured at 0, 1 and 3 h after the infusion. The participant, investigator and statistician were masked to the group assessment.Results: There was no difference in intracompartmental pressures at 1 or 3 h, between the groups. However, in patients with the baseline of compartmental pressures ≥30 mmHg, Mannitol showed a marked reduction in pressure of 8.5 mmHg at 1 h compared to almost no change in pressure in the saline group. There were no adverse events with the use of Mannitol.Conclusions: This preliminary study appears to show that Mannitol is useful in the management of the increased compartment pressure. The limitations of this study were that it only involved a small group of patients and the baseline pressures in both the groups were not comparable. More studies are required before the use of Mannitol as a standard of care in the management of compartment syndrome can be established. [ABSTRACT FROM AUTHOR]

Highlights • Cervical paraspinal muscle compartment pressures on the hinge side were significantly increased after laminoplasty at all upper, middle and lower areas. • The pressure was then significantly decreased after removal of the spinous processes on the hinge side in the upper and middle areas. • There was a difference in the pressures after laminoplasty between the open and hinge sides. Abstract Axial neck pain is a common complaint after cervical laminoplasty and the causes are still not well-understood. We hypothesized that abnormal paracervical muscle compartment pressures might be one of them. The cervical paraspinal muscle compartment pressures of 10 cadavers were measured in six different areas under four different conditions. The posterior cervical area was divided into two sides: open side and hinge side. Then each side was divided into upper, middle, and lower areas. The compartment pressures of each area were measured under four different conditions: before and after dissection of posterior paravertebral (paraspinal) muscles, after laminoplasty and after laminoplasty with removal of the spinous processes. There was a statistically significant difference between the pressures after dissection versus after laminoplasty on the hinge side at all upper, middle and lower areas [p < 0.01, <0.001 and =0.009 respectively]. There was a difference in the pressures after laminoplasty between the open and hinge sides [p < 0.001, <0.001 and =0.023 respectively]. We also found the following significant differences: the pressures between before dissection and after laminoplasty on the hinge side, as well as between after laminoplasty and after removal of the spinous process on the hinge side in the upper and middle areas [p < 0.001, =0.0016 and p = 0.002, =0.023 respectively]. Cervical paraspinal muscle compartment pressures on the hinge side were significantly increased after laminoplasty. This may be a contributor to axial neck pain following laminoplasty. The pressure was then significantly decreased after removal of the spinous processes. [ABSTRACT FROM AUTHOR]

Purpose: The forearm is prone to raised compartment pressure and it is the second most common site for compartment syndrome. The normal compartment pressure of the forearm should be known and serve as a benchmark for the diagnosis of acute and chronic compartment syndrome. This study was aimed to determine the normal compartment pressures of the forearm using a digital compartment pressure monitor.Methods: This was a prospective hospital-based study of the uninjured forearm in 30 patients, who presented with closed unilateral forearm fracture at the accident and emergency department of a tertiary health care facility, between June 2012 and December 2013. Approval was sought and obtained from institutions ethical committee. An 18 gauge bevelled-tip needle, attached to a Compass TM digital compartment pressure monitor made by Mirador USA, was used to measure the pressures in the compartments of the forearm. Data obtained were analysed using the Stata 12. Significance was determined at p < 0.05.Results: The mean age was 38.3 ± 18.3 years with male-to-female ratio of 2.3:1. The pressures in the volar compartment of the forearm ranged from 1 to 8 mmHg with a mean ± SD compartment pressure of 4.7 ± 1.5 mmHg. In the dorsal compartment the pressure ranged from 2 to 8 mmHg with a mean ± SD of 4.9 ± 1.7 mmHg SD, while the lateral compartment measurement ranged between 1 and 5 mmHg with a mean ± SD of 3.6 ± 1.1 mmHg. There was significant positive correlation (p < 0.01) between the compartment pressures in the volar, dorsal, and lateral compartments.Conclusion: The normal compartment pressure for forearm is 4.4 ± 1.6 mmHg and ranged from 1 to 8 mmHg from this study in our environment. This will serve as reference value when forearm compartment pressure is being measured. [ABSTRACT FROM AUTHOR]

Trauma surgeons frequently encounter injured limbs at risk for compartment syndrome. This article reviews data regarding the pathophysiology of compartment syndrome, factors in measuring compartment pressures, thresholds for performing fasciotomies, and outcomes from the development of compartment syndromes and performing fasciotomies. [ABSTRACT FROM AUTHOR]

Background: Compartment syndrome of any extremity is a limb-threatening emergency requiring an emergent surgical management. Thus, ruling out compartment syndrome is often high on the list of priorities when treating high-energy injuries and fractures. However, even in the most seemingly benign injuries, this dangerous diagnosis must always remain on the differential and suspicion must remain high. Case presentation: 23-year-old factory worker presents after a low energy entrapment injury to his left forearm. Initial work-up and evaluation noted an isolated radial head dislocation with a normal physical motor and sensory exam. However, maintaining high suspicion for compartment syndrome despite serial normal physical exams, led objective compartment pressure measurement leading to definitive diagnosis. Emergent surgical intervention via compartment fasciotomies was performed, along with closed reduction and ligament repair. At 1 year follow-up, the patient was well-healed, back to work with full range of motion and not activity limitations. Conclusion: Despite a seemingly benign injury pattern, and a relatively low energy mechanism, vigilant concern for compartment syndrome following any kind of entrapment injury should initiate serial examinations and compartment pressure measurements especially in circumstances with continued swelling and inability to perform an accurate clinical assessment due to an obtunded or medicated patient. [ABSTRACT FROM AUTHOR]

Acute compartment syndrome of the lower limb is a significant problem in surgical practice, the successful management of which depends upon swift diagnosis and intervention.Conventionally, diagnosis has been based upon clinical assessment; however, this can be unreliable and the potential for missed compartment syndrome remains. The supplementary use of compartment pressure monitoring has addressed some of these issues, but it remains an invasive technique, the exact role of which is still debated in the literature.Near infrared spectroscopy (NIRS) is an emerging technique in medical practice which provides a non-invasive, continuous and real time measure of local tissue oxygenation. Early experimental work and subsequent clinical studies have demonstrated that NIRS provides an accurate means of detecting compartment syndrome, and that its sensitivity in some circumstances may exceed that of monitoring compartment pressures. Despite this promise, limitations of the technique, such as difficultly monitoring the deep posterior compartment of leg using current systems, and the relative expense of the equipment, have hindered broader adoption. [ABSTRACT FROM AUTHOR]

To determine the effect of clipless and toe-clipped pedals on plantar foot pressure while cycling. Seven bikers and 11 healthy volunteers were tested on a Giant ATX Team mountain bike, Tekscan Clinical 5.24 F-scan® system with an inner sole pressure sensor, a Tacx Cycle force One Turbo Trainer and a Cateye Mity 8 computerized speedometer were used. The subjects wore Shimano M037 shoes and used a standard clipless and toe-clipped pedal. The seat height was set at 100% of subject's trochanteric height. Plantar pressures were recorded over 12 consecutive crank cycles at a constant speed for each of the power outputs. The videos were analysed to record the pressure exerted at 12 positions on the foot for each variable. Whether there is any dominance of any of the metatarsals, and any difference in plantar pressures between clipped and clipless pedal. There was a significant difference in the pressure at many positions of the foot, but the sites were different for each individual. General regression analysis indicated that pedal type had a statistically significant effect on plantar pressure at the sites of 1(st) metatarsal (p=0.042), 3(rd) metatarsal (p<0.001), 5(th) metatarsal (<0.001), 2(nd) (p=0.018) and 5(th) toe (p<0.001), lateral midfoot (p<0.001) and central heel (p<0.001) areas. Clipless pedals produce higher pressures which are more spread across the foot than toe-clipped pedals. This may have implications for their use in the prevention and/or management of overuse injuries in the knee and foot.