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1. Clinical validation of risk scoring systems to predict risk of delayed bleeding after EMR of large colorectal lesions

Author

Albéniz, Eduardo, Gimeno-García, Antonio Zebenzuy, Fraile, María, Ibáñez, Berta, Guarner-Argente, Carlos, Alonso-Aguirre, Pedro, Álvarez, Marco Antonio, Gargallo, Carla Jerusalén, Pellisé, María, Ramos Zabala, Felipe, Herreros de Tejada, Alberto, Nogales, Óscar, Martínez-Ares, David, Múgica, Fernando, de la Peña, Joaquín, Espinós, Jorge, Huerta, Alain, Álvarez, Alberto, Gonzalez-Santiago, Jesús M., Navajas, Francisco, Martínez-Cara, Juan Gabriel, Redondo-Cerezo, Eduardo, Merlo Mas, Josep, Sábado, Fernando, Rivero, Liseth, Saperas, Esteban, Soto, Santiago, Rodríguez-Sánchez, Joaquín, López-Roses, Leopoldo, Rodríguez-Téllez, Manuel, Rullán Iriarte, María, Elosua González, Alfonso, Pardeiro, Remedios, Valdivielso Cortázar, Eduardo, Concepción-Martín, Mar, Huelin Álvarez, Patricia, Colán Hernández, Juan, Cobian, Julyssa, Santiago, José, Jiménez, Alejandra, Remedios, David, López-Viedma, Bartolomé, García, Orlando, Martínez-Alcalá, Felipe, Pérez-Roldán, Francisco, Carbó, Jorge, and Enguita, Mónica

Published
2020
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3. A Scoring System to Determine Risk of Delayed Bleeding After Endoscopic Mucosal Resection of Large Colorectal Lesions

Author

Albéniz, Eduardo, Fraile, María, Ibáñez, Berta, Alonso-Aguirre, Pedro, Martínez-Ares, David, Soto, Santiago, Gargallo, Carla Jerusalén, Ramos Zabala, Felipe, Álvarez, Marco Antonio, Rodríguez-Sánchez, Joaquín, Múgica, Fernando, Nogales, Óscar, Herreros de Tejada, Alberto, Redondo, Eduardo, Pin, Noel, León-Brito, Helena, Pardeiro, Remedios, López-Roses, Leopoldo, Rodríguez-Téllez, Manuel, Jiménez, Alejandra, Martínez-Alcalá, Felipe, García, Orlando, de la Peña, Joaquín, Ono, Akiko, Alberca de las Parras, Fernando, Pellisé, María, Rivero, Liseth, Saperas, Esteban, Pérez-Roldán, Francisco, Pueyo Royo, Antonio, Eguaras Ros, Javier, Zúñiga Ripa, Alba, Concepción-Martín, Mar, Huelin-Álvarez, Patricia, Colán-Hernández, Juan, Cubiella, Joaquín, Remedios, David, Bessa i Caserras, Xavier, López-Viedma, Bartolomé, Cobian, Julyssa, González-Haba, Mariano, Santiago, José, Martínez-Cara, Juan Gabriel, Valdivielso, Eduardo, and Guarner-Argente, Carlos

Published
2016
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4. Clinical validation of risk scoring systems to predict risk of delayed bleeding after EMR of large colorectal lesions

Author

La Caixa, Caja Navarra, Albéniz, Eduardo, Gimeno-Garcia, Antonio Z., Fraile, María, Ibáñez Beroiz, Berta, Guarner-Argente, Carlos, Alonso-Aguirre, Pedro, Álvarez, Marco Antonio, Jerusalén Gargallo, Carla, Pellisé, María, Ramos-Zabala, Felipe, Herreros de Tejada, Alberto, Nogales, Oscar, Martínez-Ares, David, Múgica, Fernando, Peña, Joaquín de la, Espinós, Jorge C., Huerta, Alain, Álvarez, Alberto, Gonzalez-Santiago, Jesús M., Navajas, Francisco, Martínez-Cara, Juan Gabriel, Redondo-Cerezo, Eduardo, Merlo Mas, Josep, Sábado, Fernando, Rivero, Liseth, Saperas, Esteban, Soto, Santiago, Rodríguez-Sánchez, Joaquín, López-Roses, Leopoldo, Rodríguez-Téllez, Manuel, Rullán Iriarte, María, Elosua, Alfonso, Pardeiro, Remedios, Valdivielso Cortázar, Eduardo, Concepción-Martín, Mar, Huelin Álvarez, Patricia, Colán Hernández, Juan, Cobian, Julyssa, Santiago, José, Jiménez, Alejandra, Remedios, David, López-Viedma, Bartolomé, García, Orlando, Martínez-Alcalá, Felipe, Pérez-Roldán, Francisco, Carbó, Jorge, Enguita-Germán, Mónica, La Caixa, Caja Navarra, Albéniz, Eduardo, Gimeno-Garcia, Antonio Z., Fraile, María, Ibáñez Beroiz, Berta, Guarner-Argente, Carlos, Alonso-Aguirre, Pedro, Álvarez, Marco Antonio, Jerusalén Gargallo, Carla, Pellisé, María, Ramos-Zabala, Felipe, Herreros de Tejada, Alberto, Nogales, Oscar, Martínez-Ares, David, Múgica, Fernando, Peña, Joaquín de la, Espinós, Jorge C., Huerta, Alain, Álvarez, Alberto, Gonzalez-Santiago, Jesús M., Navajas, Francisco, Martínez-Cara, Juan Gabriel, Redondo-Cerezo, Eduardo, Merlo Mas, Josep, Sábado, Fernando, Rivero, Liseth, Saperas, Esteban, Soto, Santiago, Rodríguez-Sánchez, Joaquín, López-Roses, Leopoldo, Rodríguez-Téllez, Manuel, Rullán Iriarte, María, Elosua, Alfonso, Pardeiro, Remedios, Valdivielso Cortázar, Eduardo, Concepción-Martín, Mar, Huelin Álvarez, Patricia, Colán Hernández, Juan, Cobian, Julyssa, Santiago, José, Jiménez, Alejandra, Remedios, David, López-Viedma, Bartolomé, García, Orlando, Martínez-Alcalá, Felipe, Pérez-Roldán, Francisco, Carbó, Jorge, and Enguita-Germán, Mónica

Abstract

[Background and Aims]: The Endoscopic Resection Group of the Spanish Society of Endoscopy (GSEED-RE) model and the Australian Colonic Endoscopic Resection (ACER) model were proposed to predict delayed bleeding (DB) after EMR of large superficial colorectal lesions, but neither has been validated. We validated and updated these models., [Methods]: A multicenter cohort study was performed in patients with nonpedunculated lesions ≥20 mm removed by EMR. We assessed the discrimination and calibration of the GSEED-RE and ACER models. Difficulty performing EMR was subjectively categorized as low, medium, or high. We created a new model, including factors associated with DB in 3 cohort studies., [Results]: DB occurred in 45 of 1034 EMRs (4.5%); it was associated with proximal location (odds ratio [OR], 2.84; 95% confidence interval [CI], 1.31-6.16), antiplatelet agents (OR, 2.51; 95% CI, .99-6.34) or anticoagulants (OR, 4.54; 95% CI, 2.14-9.63), difficulty of EMR (OR, 3.23; 95% CI, 1.41-7.40), and comorbidity (OR, 2.11; 95% CI, .99-4.47). The GSEED-RE and ACER models did not accurately predict DB. Re-estimation and recalibration yielded acceptable results (GSEED-RE area under the curve [AUC], .64 [95% CI, .54-.74]; ACER AUC, .65 [95% CI, .57-.73]). We used lesion size, proximal location, comorbidity, and antiplatelet or anticoagulant therapy to generate a new model, the GSEED-RE2, which achieved higher AUC values (.69-.73; 95% CI, .59-.80) and exhibited lower susceptibility to changes among datasets., [Conclusions]: The updated GSEED-RE and ACER models achieved acceptable prediction levels of DB. The GSEED-RE2 model may achieve better prediction results and could be used to guide the management of patients after validation by other external groups. (Clinical trial registration number: NCT 03050333.)

Published
2020

5. Supplemental material for Influence of age, body mass index and comorbidity on major outcomes in acute pancreatitis, a prospective nation-wide multicentre study

Author

Moran, Robert A, García-Rayado, Guillermo, Iglesia-García, Daniel De La, Martínez-Moneo, Emma, Fort-Martorell, Esther, Lauret-Braña, Eugenia, Concepción-Martín, Mar, Ausania, Fabio, Prieto-Martínez, Carlos, González-De-Cabo, Miguel, Quesada-Vázquez, Noé, M Asunción Marcaide-Ruiz-De-Apodaca, Pajares-Díaz, José A, Díaz, Francia C, De-Benito, José L, Hinojosa-Guadix, Jennifer, Marqués-García, Pilar, Boadas, Jaume, Bajador-Andreu, Eduardo, Moreno, Oswaldo, Argüelles-Arias, Federico, Martín-Benítez, Gregorio, Tafur-Sánchez, Carla, Leal-Téllez, Jesús, Romero-Mosquera, Beatriz, Hernaez, Ruben, Papachristou, Georgios I, Vikesh K Singh, and De-Madaria, Enrique

Subjects
FOS: Clinical medicine, FOS: Biological sciences, 111199 Nutrition and Dietetics not elsewhere classified, FOS: Health sciences, 110308 Geriatrics and Gerontology, 69999 Biological Sciences not elsewhere classified, 111299 Oncology and Carcinogenesis not elsewhere classified
Abstract

Supplemental material for Influence of age, body mass index and comorbidity on major outcomes in acute pancreatitis, a prospective nation-wide multicentre study by Robert A Moran, Guillermo García-Rayado, Daniel de la Iglesia-García, Emma Martínez-Moneo, Esther Fort-Martorell, Eugenia Lauret-Braña, Mar Concepción-Martín, Fabio Ausania, Carlos Prieto-Martínez, Miguel González-de-Cabo, Noé Quesada-Vázquez, M Asunción Marcaide-Ruiz-de-Apodaca, José A Pajares-Díaz, Francia C Díaz, José L de-Benito, Jennifer Hinojosa-Guadix, Pilar Marqués-García, Jaume Boadas, Eduardo Bajador-Andreu, Oswaldo Moreno, Federico Argüelles-Arias, Gregorio Martín-Benítez, Carla Tafur-Sánchez, Jesús Leal-Téllez, Beatriz Romero-Mosquera, Ruben Hernaez, Georgios I Papachristou, Vikesh K Singh and Enrique de-Madaria in United European Gastroenterology Journal

Published
2018
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6. FACTORES ASOCIADOS A LA NECESIDAD DE NECROSECTOMÍA DE LA NECROSIS PANCREÁTICA ENCAPSULADA DRENADA CON PRÓTESIS AXIOS

Author

González González, Laura, primary, Brujats Rubirola, Anna, additional, Trias Torroglosa, Mireia, additional, de Riba Soler, Beatriz, additional, Murzi Pulgar, Marianette, additional, Concepción Martín, Mar, additional, Colan Hernández, Juan, additional, Pernas Canadell, Juan Carlos, additional, and Guarner Argente, Carlos, additional

Published
2019
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7. Influence of age, body mass index and comorbidity on major outcomes in acute pancreatitis, a prospective nation‐wide multicentre study

Author

Moran, Robert A, primary, García-Rayado, Guillermo, additional, Iglesia-García, Daniel, additional, Martínez-Moneo, Emma, additional, Fort-Martorell, Esther, additional, Lauret-Braña, Eugenia, additional, Concepción-Martín, Mar, additional, Ausania, Fabio, additional, Prieto-Martínez, Carlos, additional, González-de-Cabo, Miguel, additional, Quesada-Vázquez, Noé, additional, Marcaide-Ruiz-de-Apodaca, M Asunción, additional, Pajares-Díaz, José A, additional, Díaz, Francia C, additional, Benito, José L, additional, Hinojosa-Guadix, Jennifer, additional, Marqués-García, Pilar, additional, Boadas, Jaume, additional, Bajador-Andreu, Eduardo, additional, Moreno, Oswaldo, additional, Argüelles-Arias, Federico, additional, Martín-Benítez, Gregorio, additional, Tafur-Sánchez, Carla, additional, Leal-Téllez, Jesús, additional, Romero-Mosquera, Beatriz, additional, Hernaez, Ruben, additional, Papachristou, Georgios I, additional, Singh, Vikesh K, additional, and Madaria, Enrique, additional

Published
2018
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8. Su1690 Risk Factors Associated With Incomplete Endoscopic Resection of Large Colorectal Lesions. Results From the Endoscopic Resection Group of the Spanish Society of Digestive Endoscopy

Author

Martinez-Ares, David, primary, Albeniz, Eduardo, additional, Gargallo, Carla, additional, Guarner, Carlos, additional, Fraile Gonzalez, Maria, additional, Alonso, Pedro, additional, Ramos Zabala, Felipe, additional, de la Peña, Joaquin, additional, Nogales Rincon, Oscar, additional, Gabriel martinez-cara, Juan, additional, Herreros-de-Tejada, Alberto, additional, Santiago, Jose, additional, Alvarez-Gonzalez, Marco A., additional, Bessa, Xavier, additional, Valdivielso, Eduardo, additional, Pinazas, Nerea Quintans, additional, Cobian, Julissa, additional, Mugica, Fernando, additional, Rullan, Maria, additional, Mosquera, Beatriz Romero, additional, Zuñiga Ripa, Alba, additional, Espinos, Jorge C., additional, Repiso, Alejandro, additional, Gonzalez-Santiago, Jesus M., additional, Alvarez, Alberto, additional, Saperas, Esteban, additional, Huelin, Patricia, additional, Concepción-Martín, Mar, additional, Colán, Juan A., additional, Merlo, Jose, additional, Pellise, Maria, additional, Rivero, Liseth, additional, and Rodríguez-Téllez, Manuel, additional

Published
2017
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9. Marked Differences in Fasting Time and Length of Stay in Mild Acute Pancreatitis Between Tertiary Centers

Author

Concejo, Federico Bolado, primary, Marra-López, Carlos, additional, García-Rayado, Guillermo, additional, Prieto-Martínez, Carlos, additional, López-Serrano, Antonio, additional, Lariño-Noia, Jose, additional, Fort-Martorell, Esther, additional, Lauret-Braña, Eugenia, additional, Concepción-Martín, Mar, additional, Ausania, Fabio, additional, and de-Madaria, Enrique, additional

Published
2017
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10. A Scoring System to Determine Risk of Delayed Bleeding After Endoscopic Mucosal Resection of Large Colorectal Lesions

Author

Albéniz, Eduardo, Fraile, María, Ibáñez, Berta, Alonso-Aguirre, Pedro, Martínez-Ares, David, Soto, Santiago, Gargallo, Carla Jerusalén, Ramos Zabala, Felipe, Álvarez, Marco Antonio, Rodríguez-Sánchez, Joaquín, Múgica, Fernando, Nogales, Óscar, Herreros de Tejada, Alberto, Redondo, Eduardo, Pin, Noel, León-Brito, Helena, Pardeiro, Remedios, López-Roses, Leopoldo, Rodríguez-Téllez, Manuel, Jiménez, Alejandra, Martínez-Alcalá, Felipe, García, Orlando, de la Peña, Joaquín, Ono, Akiko, Alberca de Las Parras, Fernando, Pellisé, María, Rivero, Liseth, Saperas, Esteban, Pérez-Roldán, Francisco, Pueyo Royo, Antonio, Eguaras Ros, Javier, Zúñiga Ripa, Alba, Concepción-Martín, Mar, Huelin-Álvarez, Patricia, Colán-Hernández, Juan, Cubiella, Joaquín, Remedios, David, Bessa I Caserras, Xavier, López-Viedma, Bartolomé, Cobian, Julyssa, González-Haba, Mariano, Santiago, José, Martínez-Cara, Juan Gabriel, Valdivielso, Eduardo, Guarner-Argente, Carlos, and Endoscopic Mucosal Resection Endoscopic Spanish Society Group

Subjects
Adult, Male, medicine.medical_specialty, ASA, Mucosectomy, Endoscopic Mucosal Resection, Endoscopic mucosal resection, Gastroenterology, Risk Assessment, Decision Support Techniques, 03 medical and health sciences, Young Adult, 0302 clinical medicine, Internal medicine, medicine, Humans, Prospective Studies, Risk factor, Prospective cohort study, Aged, Aged, 80 and over, Aspirin, Hepatology, Receiver operating characteristic, Colon Cancer, business.industry, Prognostic Factor, Odds ratio, Middle Aged, Confidence interval, Surgery, Spain, 030220 oncology & carcinogenesis, 030211 gastroenterology & hepatology, Female, business, Risk assessment, Gastrointestinal Hemorrhage, medicine.drug
Abstract

BACKGROUND & AIMS: After endoscopic mucosal resection (EMR) of colorectal lesions, delayed bleeding is the most common serious complication, but there are no guidelines for its prevention. We aimed to identify risk factors associated with delayed bleeding that required medical attention after discharge until day 15 and develop a scoring system to identify patients at risk. METHODS: We performed a prospective study of 1214 consecutive patients with nonpedunculated colorectal lesions 20 mm or larger treated by EMR (n = 1255) at 23 hospitals in Spain, from February 2013 through February 2015. Patients were examined 15 days after the procedure, and medical data were collected. We used the data to create a delayed bleeding scoring system, and assigned a weight to each risk factor based on the beta parameter from multivariate logistic regression analysis. Patients were classified as being at low, average, or high risk for delayed bleeding. RESULTS: Delayed bleeding occurred in 46 cases (3.7%, 95% confidence interval, 2.7%-4.9%). In multivariate analysis, factors associated with delayed bleeding included age >= 75 years (odds ratio [OR], 2.36; P= 40 mm (OR, 1.91; P

Published
2015

11. IL-6, IL-10 and TNFα do not improve early detection of post-endoscopic retrograde cholangiopancreatography acute pancreatitis: a prospective cohort study

Author

Concepción-Martín, Mar, primary, Gómez-Oliva, Cristina, additional, Juanes, Ana, additional, Mora, Josefina, additional, Vidal, Silvia, additional, Díez, Xavier, additional, Torras, Xavier, additional, Sainz, Sergio, additional, Villanueva, Candid, additional, Farré, Antoni, additional, Guarner-Argente, Carlos, additional, and Guarner, Carlos, additional

Published
2016
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13. Nation-wide multicenter prospective validation of the new severity classifications of acute pancreatitis

Author

de-Madaria, Enrique, primary, Bolado, Federico, additional, Canaval-Zuleta, Héctor J., additional, Marra-López, Carlos, additional, Hernándo-Alonso, Ana I., additional, Val, Adolfo del, additional, Rivera-Irigoin, Robin, additional, Ferrández, Ángel, additional, Boadas, Jaume, additional, Millastre-Bocos, Judith, additional, Pascual-Moreno, Isabel, additional, Rodríguez-Oballe, Juan A., additional, López-Serrano, Antonio, additional, Ruiz-Rebollo, María L., additional, Viejo-Almanzor, Alejandro, additional, Lariño-Noia, José, additional, Martínez-Moneo, Emma, additional, Fort-Martorel, Esther, additional, Lauret-Braña, María E., additional, Concepción-Martín, Mar, additional, Ausania, Fabio, additional, Martínez-Ares, David, additional, and Grau-García, Francisco J., additional

Published
2015
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14. Mo1339 Nation-Wide Multicenter Prospective Validation of the New Severity Classifications of Acute Pancreatitis

Author

de-Madaria, Enrique, primary, Bolado, Federico, additional, Prieto-Martínez, Carlos, additional, de la Higuera, Belén González, additional, Canaval-Zuleta, Héctor J., additional, Lareu, Nelly Balza, additional, de Cabo, Miguel González, additional, Marra-López, Carlos, additional, de Apodaca, María A. Marcaide Ruiz, additional, Orive-Calzada, Aitor, additional, Hernando-Alonso, Ana I., additional, Pajares-Díaz, José Antonio, additional, Gómez-Anta, Ignacio, additional, del Val, Adolfo, additional, Díaz, Francia C., additional, Ferrandez, Angel, additional, Rivera-Irigoin, Robin, additional, Grau-García, Francisco J., additional, Boadas, Jaume, additional, Millastre, Judith, additional, Pascual-Moreno, Isabel, additional, Rodríguez-Oballe, Juan A., additional, López-Serrano, Antonio, additional, Ruiz-Rebollo, María L., additional, Viejo-Almanzor, Alejandro, additional, Lariño-Noia, Jose, additional, Martínez-Moneo, Emma, additional, Fort-Martorell, Esther, additional, Lauret-Braña, María Eugenia, additional, Romero-Mosquera, Beatriz, additional, Concepción-Martín, Mar, additional, Ausania, Fabio, additional, Prada, José I. Rodríguez, additional, Suárez, Silvia Guzmán, additional, and Zapater, Pedro, additional

Published
2015
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