1. Identification of a novel ITGAX::RN7SL2 fusion in acute myelocytic leukemia.
- Author
-
Su, Zhan, Cong, Beibei, and Li, Xiaojuan
- Subjects
- *
ANEMIA diagnosis , *PROTEINS , *PHYSICAL diagnosis , *LYMPH nodes , *MYELODYSPLASTIC syndromes , *ERYTHROCYTES , *FATIGUE (Physiology) , *HEADACHE , *CHROMOSOME abnormalities , *DNA , *GENES , *RNA , *GENE expression , *KARYOTYPES , *CYTOPLASM , *GENE expression profiling , *SEQUENCE analysis ,BONE marrow examination - Abstract
The article presents a case study of a 55-year-old female diagnosed with myelodysplastic syndromes (MDS) progressing to acute myelocytic leukemia (AML), revealing a novel fusion gene detected through transcriptome sequencing. Topics discussed include the clinical history of the patient, molecular characterization of the fusion gene, and the potential implications of non-coding Ribonucleic Acid (RNA) involvement in leukemia pathogenesis.
- Published
- 2024
- Full Text
- View/download PDF