289 results on '"Conn, Graeme L."'
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2. tRNA m1G9 modification depends on substrate-specific RNA conformational changes induced by the methyltransferase Trm10
3. Differential roles of putative arginine fingers of AAA+ ATPases Rvb1 and Rvb2
4. 30S subunit recognition and G1405 modification by the aminoglycoside-resistance 16S ribosomal RNA methyltransferase RmtC
5. Application of Isothermal Titration Calorimetry (ITC) to Biomolecular Interactions
6. Crystal Structure of a Conserved Ribosomal Protein-RNA Complex
7. Antisense, but not sense, repeat expanded RNAs activate PKR/eIF2α-dependent ISR in C9ORF72 FTD/ALS
8. Author response: Antisense, but not sense, repeat expanded RNAs activate PKR/eIF2α-dependent ISR in C9ORF72 FTD/ALS
9. Di-berberine conjugates as chemical probes ofPseudomonas aeruginosaMexXY-OprM efflux function and inhibition
10. tRNA m1G9 modification depends on substrate-specific RNA conformational changes induced by the methyltransferase Trm10
11. Adenovirus VA RNA: An essential pro-viral non-coding RNA
12. Trimethylation of Elongation Factor-Tu by the Dual Thermoregulated Methyltransferase EftM Does Not Impact Its Canonical Function in Translation
13. Ribosome-targeting antibiotics and resistance via ribosomal RNA methylation
14. Tied up in knots: Untangling substrate recognition by the SPOUT methyltransferases
15. Tuberactinomycin antibiotics: Biosynthesis, anti-mycobacterial action, and mechanisms of resistance
16. Expansion of the aminoglycoside-resistance 16S rRNA (m1A1408) methyltransferase family: Expression and functional characterization of four hypothetical enzymes of diverse bacterial origin
17. Dissection of the Adenoviral VA RNAI Central Domain Structure Reveals Minimum Requirements for RNA-mediated Inhibition of PKR
18. Molecular recognition and modification of the 30S ribosome by the aminoglycoside-resistance methyltransferase NpmA
19. Antisense, but not sense, repeat expanded RNAs activate PKR/eIF2α-dependent integrated stress response in C9orf72 FTD/ALS
20. 50S subunit recognition and modification by the Mycobacterium tuberculosis ribosomal RNA methyltransferase TlyA
21. Role of helical structure and dynamics in oligoadenylate synthetase 1 (OAS1) mismatch tolerance and activation by short dsRNAs
22. 50S subunit recognition and modification by the Mycobacterium tuberculosis ribosomal RNA methyltransferase TlyA
23. Targeted Redesign of Suramin Analogs for Novel Antimicrobial Lead Development
24. RNA Tertiary Structure and Protein Recognition in an L11-RNA Complex
25. Heterozygous OAS1 gain-of-function variants cause an autoinflammatory immunodeficiency
26. Aminoglycoside resistance genes sgm and kgmB protect bacterial but not yeast small ribosomal subunits in vitro despite high conservation of the rRNA A-site
27. Raman and Raman optical activity (ROA) analysis of RNA structural motifs
28. Investigations of conformational transitions in proteins and RNA using 2DCOS Raman and 2DCOS Raman optical activity spectroscopies
29. Heterologous Escherichia coli Expression, Purification and Characterization of the GrmA Aminoglycoside-Resistance Methyltransferase
30. Ribosome-targeting antibiotics and resistance viaribosomal RNA methylation
31. Critical residues for cofactor binding and catalytic activity in the aminoglycoside resistance methyltransferase Sgm
32. Plasmid Template Design and In Vitro Transcription of Short RNAs Within a “Structure Cassette” for Structure Probing Experiments
33. Cis-Acting Ribozymes for the Production of RNA In Vitro Transcripts with Defined 5′ and 3′ Ends
34. General Protocols for Preparation of Plasmid DNA Template, RNA In Vitro Transcription, and RNA Purification by Denaturing PAGE
35. T1R2, T1R3, and the Detection of Sweet Stimuli
36. Crystal Structures of the Sweet Protein MNEI: Insights into Sweet Protein-Receptor Interactions
37. Reduced Sweetness of a Monellin (MNEI) Mutant Results from Increased Protein Flexibility and Disruption of a Distant Poly-(L-Proline) II Helix
38. Antibiotic Substrate Selectivity of Pseudomonas aeruginosa MexY and MexB Efflux Systems Is Determined by a Goldilocks Affinity
39. Human OAS1 activation is highly dependent on both RNA sequence and context of activating RNA motifs
40. Aminoglycoside conformation and ring substituents dictate evasion from bacterial resistance mechanisms
41. Ribosomal Protein L11 Selectively Stabilizes a Tertiary Structure of the GTPase Center rRNA Domain
42. Structural insights into the function of aminoglycoside-resistance A1408 16S rRNA methyltransferases from antibiotic-producing and human pathogenic bacteria
43. Substrate recognition by the Pseudomonas aeruginosa EF-Tu–modifying methyltransferase EftM
44. Functionally critical residues in the aminoglycoside resistance-associated methyltransferase RmtC play distinct roles in 30S substrate recognition
45. Determination of the target nucleosides for members of two families of 16S rRNA methyltransferases that confer resistance to partially overlapping groups of aminoglycoside antibiotics
46. The PKR-binding domain of adenovirus VA RNAI exists as a mixture of two functionally non-equivalent structures
47. Analysis of adenovirus VA RNAI structure and stability using compensatory base pair modifications
48. Raman and Raman optical activity (ROA) analysis of RNA structural motifs in Domain I of the EMCV IRES
49. A functional ribosomal RNA tertiary structure involves a base triple interaction
50. Solution structures of DNA*RNA hybrids with purine-rich and pyrimidine-rich strands: comparison with the homologous DnA and RNA duplexes
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