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1. Midterm outcomes with a sutureless aortic bioprosthesis in a prospective multicenter cohort study

Author

Zannis, Kostantinos, Pfeiffer, Steffen, Santarpino, Giuseppe, Shrestha, Malakh, Sarikouch, Samir, Gummert, Jan F., Mohr, Friedrich W., Dohmen, Pascal, Stalder, Mario, Roost, Eva, Filipiak, Krzysztof, Niklewski, Tomasz, Madonna, Francesco, Roques, Xavier, Flameng, Willem J., Laczkovics, Axel M.M., Bechtel, Matthias, Prat, Alain G., Banfi, Carlo, Dapunt, Otto E., Eichstaedt, Harald C., Harringer, Wolfgang, Carstens-Fitz, Ulrike, Spyt, Tom J., Wimmer-Greinecker, Jan Gerhard, Machner, Matthias, Tan, Erwin S.H., Casselman, Filip P.A., Yilmaz, Alaaddin, Sonker, Uday, Bleiziffer, Sabine, Oberwalder, Peter J., Kocher, Alfred A., Seitelberger, Rainald, Treede, Hendrik, Conradi, Leonard, Cocchieri, Riccardo, De Mol, Bas, Roussel, Jean-Christian, Despins, Philippe, Jakob, Heinz G., Wendt, Daniel, Fischlein, Theodor, Meuris, Bart, Folliguet, Thierry, Hakim-Meibodi, Kavous, Misfeld, Martin, Carrel, Thierry, Zembala, Marian, Cerutti, Elisa, Asch, Federico M., and Haverich, Axel

Published
2022
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2. The sutureless aortic valve at 1 year: A large multicenter cohort study

Author

Folliguet, Thierry, Zannis, Kostantinos, Pfeiffer, Steffen, Santarpino, Giuseppe, Shrestha, Malakh, Sarikouch, Samir, Gummert, Jan F., Mohr, Friedrich W., Dohmen, Pascal, Stalder, Mario, Roost, Eva, Filipiak, Krzysztof, Niklewski, Tomasz, Roques, Xavier, Flameng, Willem J., Laczkovics, Axel M.M., Bechtel, Matthias, Prat, Alain G., Banfi, Carlo, Dapunt, Otto E., Eichstaedt, Harald C., Harringer, Wolfgang, Carstens-Fitz, Ulrike, Spyt, Tom J., Wimmer-Greinecker, Jan Gerhard, Machner, Matthias, Tan, Erwin S.H., Casselman, Filip P.A., Yilmaz, Alaaddin, Sonker, Uday, Bleiziffer, Sabine, Oberwalder, Peter J., Kocher, Alfred A., Seitelberger, Rainald, Treede, Hendrik, Conradi, Leonard, Cocchieri, Riccardo, De Mol, Bas, Roussel, Jean-Christian, Despins, Philippe, Jakob, Heinz G., Wendt, Daniel, Fischlein, Theodor, Meuris, Bart, Hakim-Meibodi, Kavous, Misfeld, Martin, Carrel, Thierry, Zembala, Marian, Gaggianesi, Sara, Madonna, Francesco, Laborde, François, Asch, Federico, and Haverich, Axel

Published
2016
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3. Midterm outcomes with a sutureless aortic bioprosthesis in a prospective multicenter cohort study

Author

Fischlein, Theodor, primary, Meuris, Bart, additional, Folliguet, Thierry, additional, Hakim-Meibodi, Kavous, additional, Misfeld, Martin, additional, Carrel, Thierry, additional, Zembala, Marian, additional, Cerutti, Elisa, additional, Asch, Federico M., additional, Haverich, Axel, additional, Zannis, Kostantinos, additional, Pfeiffer, Steffen, additional, Santarpino, Giuseppe, additional, Shrestha, Malakh, additional, Sarikouch, Samir, additional, Gummert, Jan F., additional, Mohr, Friedrich W., additional, Dohmen, Pascal, additional, Stalder, Mario, additional, Roost, Eva, additional, Filipiak, Krzysztof, additional, Niklewski, Tomasz, additional, Madonna, Francesco, additional, Roques, Xavier, additional, Flameng, Willem J., additional, Laczkovics, Axel M.M., additional, Bechtel, Matthias, additional, Prat, Alain G., additional, Banfi, Carlo, additional, Dapunt, Otto E., additional, Eichstaedt, Harald C., additional, Harringer, Wolfgang, additional, Carstens-Fitz, Ulrike, additional, Spyt, Tom J., additional, Wimmer-Greinecker, Jan Gerhard, additional, Machner, Matthias, additional, Tan, Erwin S.H., additional, Casselman, Filip P.A., additional, Yilmaz, Alaaddin, additional, Sonker, Uday, additional, Bleiziffer, Sabine, additional, Oberwalder, Peter J., additional, Kocher, Alfred A., additional, Seitelberger, Rainald, additional, Treede, Hendrik, additional, Conradi, Leonard, additional, Cocchieri, Riccardo, additional, De Mol, Bas, additional, Roussel, Jean-Christian, additional, Despins, Philippe, additional, Jakob, Heinz G., additional, and Wendt, Daniel, additional

Published
2022
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4. Clinical and haemodynamic outcomes in 658 patients receiving the Perceval sutureless aortic valve : early results from a prospective European multicentre study (the Cavalier Trial)

Author

Laborde, François, Fischlein, Theodor, Hakim-Meibodi, Kavous, Misfeld, Martin, Carrel, Thierry, Zembala, Marian, Madonna, Francesco, Meuris, Bart, Haverich, Axel, Shrestha, Malakh, Folliguet, Thierry, Zannis, Kostantinos, Pfeiffer, Steffen, Santarpino, Giuseppe, Sarikouch, Samir, Bara, Christoph, Gummert, Jan F, Mohr, Friedrich W, Dohmen, Pascal, Stalder, Mario, Roost, Eva, Filipiak, Krzysztof, Niklewski, Tomasz, Roques, Xavier, Flameng, Willem J, Laczkovics, Axel M M, Bechtel, Matthias, Prat, Alain G, Banfi, Carlo, Dapunt, Otto E, Eichstaedt, Harald C, Harringer, Wolfang, Carstens-Fitz, Ulrike, Spyt, Tom J, Gerhard Wimmer-Greinecker, Jan, Machner, Matthias, Tan, Erwin S H, Casselman, Filip P A, Yilmaz, Alaaddin, Sonker, Uday, Bleiziffer, Sabine, Oberwalder, Peter J, Kocher, Alfred A, Seitelberger, Rainald, Treede, Hendrik, Conradi, Leonard, Cocchieri, Riccardo, De Mol, Bas, Roussel, Jean-Christian, Despins, Philippe, Jakob, Heinz G., and Wendt, Daniel

Subjects
Male, Pulmonary and Respiratory Medicine, Aortic valve, medicine.medical_specialty, Medizin, 610 Medicine & health, 030204 cardiovascular system & hematology, Prosthesis Design, Preoperative care, law.invention, Congenital Aortic Valve Insufficiency, 03 medical and health sciences, 0302 clinical medicine, Bicuspid aortic valve, Aortic valve replacement, law, Internal medicine, medicine, Cardiopulmonary bypass, Humans, Prospective Studies, Prospective cohort study, Stroke, Device Removal, Aged, Aged, 80 and over, Heart Valve Prosthesis Implantation, business.industry, Hemodynamics, General Medicine, medicine.disease, Surgery, Europe, medicine.anatomical_structure, 030228 respiratory system, Aortic Valve, Heart Valve Prosthesis, Cardiology, Female, Cardiology and Cardiovascular Medicine, business
Abstract

OBJECTIVES The aim of the Cavalier trial was to evaluate the safety and performance of the Perceval sutureless aortic valve in patients undergoing aortic valve replacement (AVR). We report the 30-day clinical and haemodynamic outcomes from the largest study cohort with a sutureless valve. METHODS From February 2010 to September 2013, 658 consecutive patients (mean age 77.8 years; 64.4% females; mean logistic EuroSCORE 10.2%) underwent AVR in 25 European Centres. Isolated AVRs were performed in 451 (68.5%) patients with a less invasive approach in 219 (33.3%) cases. Of the total, 40.0% were octogenarians. Congenital bicuspid aortic valve was considered an exclusion criterion. RESULTS Implantation was successful in 628 patients (95.4%). In isolated AVR through sternotomy, the mean cross-clamp time and the cardiopulmonary bypass (CPB) time were 32.6 and 53.7 min, and with the less invasive approach 38.8 and 64.5 min, respectively. The 30-day overall and valve-related mortality rates were 3.7 and 0.5%, respectively. Valve explants, stroke and endocarditis occurred in 0.6, 2.1 and in 0.1% of cases, respectively. Preoperative mean and peak pressure gradients decreased from 44.8 and 73.24 mmHg to 10.24 and 19.27 mmHg at discharge, respectively. The mean effective orifice area improved from 0.72 to 1.46 cm(2). CONCLUSIONS The current 30-day results show that the Perceval valve is safe (favourable haemodynamic effect and low complication rate), and can be implanted with a fast and reproducible technique after a short learning period. Short cross-clamp and CPB times were achieved in both isolated and combined procedures. The Perceval valve represents a promising alternative to biological AVR, especially with a less invasive approach and in older patients.

Published
2016
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5. The sutureless aortic valve at 1 year: A large multicenter cohort study

Author

Fischlein, Theodor, primary, Meuris, Bart, additional, Hakim-Meibodi, Kavous, additional, Misfeld, Martin, additional, Carrel, Thierry, additional, Zembala, Marian, additional, Gaggianesi, Sara, additional, Madonna, Francesco, additional, Laborde, François, additional, Asch, Federico, additional, Haverich, Axel, additional, Folliguet, Thierry, additional, Zannis, Kostantinos, additional, Pfeiffer, Steffen, additional, Santarpino, Giuseppe, additional, Shrestha, Malakh, additional, Sarikouch, Samir, additional, Gummert, Jan F., additional, Mohr, Friedrich W., additional, Dohmen, Pascal, additional, Stalder, Mario, additional, Roost, Eva, additional, Filipiak, Krzysztof, additional, Niklewski, Tomasz, additional, Roques, Xavier, additional, Flameng, Willem J., additional, Laczkovics, Axel M.M., additional, Bechtel, Matthias, additional, Prat, Alain G., additional, Banfi, Carlo, additional, Dapunt, Otto E., additional, Eichstaedt, Harald C., additional, Harringer, Wolfgang, additional, Carstens-Fitz, Ulrike, additional, Spyt, Tom J., additional, Wimmer-Greinecker, Jan Gerhard, additional, Machner, Matthias, additional, Tan, Erwin S.H., additional, Casselman, Filip P.A., additional, Yilmaz, Alaaddin, additional, Sonker, Uday, additional, Bleiziffer, Sabine, additional, Oberwalder, Peter J., additional, Kocher, Alfred A., additional, Seitelberger, Rainald, additional, Treede, Hendrik, additional, Conradi, Leonard, additional, Cocchieri, Riccardo, additional, De Mol, Bas, additional, Roussel, Jean-Christian, additional, Despins, Philippe, additional, Jakob, Heinz G., additional, and Wendt, Daniel, additional

Published
2016
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