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1. Digitising diabetes education for a safer Ramadan: Design, delivery, and evaluation of massive open online courses in Ramadan-focused diabetes education

Author

Mackenzie, Scott C., Dickson, Jane, Mehar, Salma, Yusof, Barakatun Nisak Mohd, Alselmi, Adhari, Aksi, Bilal, Baxter, Mats Stage, Bickerton, Alex, Bharaj, Harnovdeep Singh, Conway, Nicholas, Cumming, Kirsten M., Lim, Lee-Ling, Lessan, Nader, Ghouri, Nazim, Flax, Tracey T., Osei-Kwasi, Hibbah A., Teo, Michelle ES, Waqar, Salman, Hassanein, Mohamed, and Wake, Deborah J.

Published
2024
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5. Turning data into information : the use of new technologies to improve the delivery of healthcare for people with diabetes

Author

Conway, Nicholas Thomas and Smith, Blair

Subjects
616.4
Abstract

Introduction The rapid growth and maturation of Information technologies over recent decades has had a transformative effect on healthcare delivery. As our use of such systems increases, so too does the volume of routinely collected patient data. Accessing these data with a view to providing meaningful information to individuals remains a challenge. This thesis aims to assess the effectiveness of eHealth interventions that tailor information to users’ specific requirements; and describe the implementation and evaluation of a clinical decision support system (CDSS) for diabetes with a view to improving the care of those with diabetes. Methods This study consisted of two phases. A systematic review was conducted for trials of tailored eHealth messaging in the management of chronic disease, assessing objectively measured clinical processes and outcomes. Following this, a CDSS for diabetes was developed and implemented within a diabetes electronic health record. The CDSS was evaluated via a mixed methods approach to assess user satisfaction and interaction with the system and to detect any changes in clinical processes and outcomes. Results The systematic review identified 22 studies that met the eligibility criteria. There was limited evidence that tailored eHealth messaging was associated with improved clinical processes and outcomes, but study quality was poor. The CDSS was successfully implemented within the diabetes EHR with favourable feedback from users and evidence of improved efficiencies in working practices. Adherence to guidelines was markedly improved when compared to a closely matched control population. There was an observed small but significant improvement in glycaemic control and a decrease in progression of kidney disease. Conclusion The ubiquitous nature of information technologies is testimony to the benefits that they bring to our everyday lives, including within the healthcare setting. This study has demonstrated that healthcare professionals (HCPs) caring for people with diabetes recognise the value of informatics in routine care via the use of a CDSS. This study has shown that a CDSS has the potential to improve clinical outcomes primarily by its effect on clinical processes i.e. adherence to guidelines. The diverse and complex nature of such technologies makes it difficult to assess the active component(s) effecting behaviour change. Ultimately, this limits generalisability into other settings. In this study, the active components of the CDSS can be identified as being improved efficiencies in working practices, whilst avoiding adverse effects on patient or user experience. It is tempting to infer that tailoring the CDSS messages to end-users (either patient or HCP) will improve outcomes further, however the existing evidence does not allow for this specific conclusion to be drawn. It is therefore imperative that future studies attempt to address this by recognising the complex nature of eHealth interventions and attempting to delineate the active component(s).

Published
2017

7. Glycaemic control trends in people with type 1 diabetes in Scotland 2004–2016

Author

Mair, Colette, Wulaningsih, Wahyu, Jeyam, Anita, McGurnaghan, Stuart, Blackbourn, Luke, Kennon, Brian, Leese, Graham, Lindsay, Robert, McCrimmon, Rory J., McKnight, John, Petrie, John R., Sattar, Naveed, Wild, Sarah H., Conway, Nicholas, Craigie, Ian, Robertson, Kenneth, Bath, Louise, McKeigue, Paul M., Colhoun, Helen M., and on behalf of the Scottish Diabetes Research Network (SDRN) Epidemiology Group

Published
2019
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9. Design, synthesis, and testing toward a 57-codon genome

Author

Ostrov, Nili, Landon, Matthieu, Guell, Marc, Kuznetsov, Gleb, Teramoto, Jun, Cervantes, Natalie, Zhou, Minerva, Singh, Kerry, Napolitano, Michael G., Moosburner, Mark, Shrock, Ellen, Pruitt, Benjamin W., Conway, Nicholas, Goodman, Daniel B., Gardner, Cameron L., Tyree, Gary, Gonzales, Alexandra, Wanner, Barry L., Norville, Julie E., Lajoie, Marc J., and Church, George M.

Published
2016

20. Multicentre service evaluation of presentation of newly diagnosed cancers and type 1 diabetes in children in the UK during the COVID-19 pandemic

Author

Williams, Gemma, primary, McLean, Ross, additional, Liu, Jo-Fen, additional, Ritzmann, Timothy A, additional, Dandapani, Madhumita, additional, Shanmugavadivel, Dhurgshaarna, additional, Sachdev, Pooja, additional, Brougham, Mark, additional, Mitchell, Rod T, additional, Conway, Nicholas T, additional, Law, James, additional, Cunnington, Alice, additional, Ogunnaike, Gbemi, additional, Brougham, Karen, additional, Bayman, Elizabeth, additional, and Walker, David, additional

Published
2021
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21. 1187 A multi-centre service evaluation of the impact of the COVID-19 pandemic on presentation of newly diagnosed cancers and type 1 diabetes in children in the UK

Author

Walker, David, primary, McLean, Ross, additional, Liu, Jo-Fen, additional, Ritzmann, Timothy, additional, Dandapani, Madhumita, additional, Shanmugavadivel, Dhurgshaarna, additional, Sachdev, Pooja, additional, Brougham, Mark, additional, Mitchell, Rod, additional, Conway, Nicholas, additional, Walker, David, additional, Law, James, additional, Cunnington, Alice, additional, Ogunnaike, Gbemi, additional, Brougham, Karen, additional, Bayman, Elizabeth, additional, and Williams, Gemma, additional

Published
2021
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22. A longitudinal perspective on user uptake of an electronic personal health record for diabetes, with respect to patient demographics:10 years of My Diabetes My Way

Author

Conway, Nicholas Thomas, Bluett, Michael, Shields, Cathy, Taylor, Andrew, Wake, Deborah J, and Cunningham, Scott G.

Abstract

IntroductionThe growing prevalence of diabetes has increased the need for scalable technologies to improve outcomes. My Diabetes My Way (MDMW) is an electronic personal health record (ePHR) available to all people with diabetes in Scotland since 2010, associated with improved clinical outcomes amongst users. MDMW pulls data from a national clinician-facing informatics platform and provides self-management and educational information. This study aims to describe MDMW user demographics through time with respect to the national diabetes population, with a view to addressing potential health inequalities.MethodsAggregate data were obtained retrospectively from the MDMW database and annual Scottish Diabetes Survey (SDS) from 2010 -2020. Variables included diabetes type, sex, age, socioeconomic status, ethnicity and glycaemic control. Prevalence of MDMW uptake was calculated using corresponding SDS data as denominators. Comparisons between years and demographic sub-groups were made using Chi Squared tests.ResultsOverall uptake of MDMW has steadily increased since implementation. By 2020, of all people with T1D or T2D in Scotland, 13% were fully enrolled to MDMW (39,881/312,326). There was proportionately greater numbers of users in younger, more affluent demographic groups (with a clear social gradient) with better glycaemic control. As uptake has increased through time, so too has the observed gaps between different demographic sub-groups.ConclusionThe large number of MDMW users is encouraging, but remains a minority of people with diabetes in Scotland. There is a risk that innovations like MDMW can widen health inequalities and it is incumbent upon healthcare providers to identify strategies to prevent this.

Published
2021

38. Viral Etiology and the Impact of Codetection in Young Children Presenting With Influenza-Like Illness

Author

Lim, Faye J., primary, Wake, Zoe V., additional, Levy, Avram, additional, Tempone, Simone, additional, Moore, Hannah C., additional, Richmond, Peter C., additional, de Klerk, Nicholas, additional, Conway, Nicholas T., additional, Keil, Anthony D., additional, Effler, Paul V., additional, Smith, David W., additional, and Blyth, Christopher C., additional

Published
2016
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42. MEMS amplification of piezoelectric strain for in-plane actuation

Author

Sang-Gook Kim., Massachusetts Institute of Technology. Department of Mechanical Engineering., Conway, Nicholas J. (Nicholas James), 1979, Sang-Gook Kim., Massachusetts Institute of Technology. Department of Mechanical Engineering., and Conway, Nicholas J. (Nicholas James), 1979

Abstract

Thesis (S.M.)--Massachusetts Institute of Technology, Dept. of Mechanical Engineering, 2003., Includes bibliographical references (p. 61-63)., by Nicholas J. Conway., S.M.

Published
2014

43. eHealth and the use of individually tailored information: A systematic review.

Author

Conway, Nicholas, Webster, Clare, Smith, Blair, and Wake, Deborah

Subjects
*BEHAVIOR modification, *CHRONIC diseases, *CLINICAL medicine, *MEDICAL information storage & retrieval systems, *EVALUATION of medical care, *MEDICAL protocols, *MEDLINE, *TELEMEDICINE, *SYSTEMATIC reviews
Abstract

Tailored messages are those that specifically target individuals following an assessment of their unique characteristics. This systematic review assesses the evidence regarding the effectiveness of tailoring within eHealth interventions aimed at chronic disease management. OVID Medline/Embase databases were searched for randomised control trials, controlled clinical, trials, before -after studies, and time series analyses from inception - May 2014. Objectively measured clinical processes/outcomes were considered. Twenty-two papers were eligible for inclusion: 6/22 used fully tailored messaging and 16/22 used partially tailored messages. Two studies isolated tailoring as the active component. The remainder compared intervention with standard care. In all, 12/16 studies measuring clinical processes and 2/6 studies reporting clinical outcomes showed improvements, regardless of target group. Study quality was low and design did not allow for identification of interventions’ active component. Heterogeneity precluded meta-analysis. This review has demonstrated that there is a lack of evidence to suggest that tailoring within an eHealth context confers benefit over non-tailored eHealth interventions. [ABSTRACT FROM AUTHOR]

Published
2017
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44. Viral Etiology and the Impact of Codetection in Young Children Presenting With Influenza-Like Illness.

Author

Lim, Faye J., Wake, Zoe V., Levy, Avram, Tempone, Simone, Moore, Hannah C., Richmond, Peter C., de Klerk, Nicholas, Conway, Nicholas T., Keil, Anthony D., Effler, Paul V., Smith, David W., and Blyth, Christopher C.

Subjects
RESPIRATORY infections in children, CHILDREN'S health, POLYMERASE chain reaction, ANTIBIOTICS, DRUG efficacy, DIAGNOSIS, THERAPEUTICS
Abstract

Background. Children with acute respiratory tract infection (ARTI) frequently exhibit virus-virus codetection, yet the clinical significance of ARTI remains contentious. Using data from a prospective cohort of children with influenza-like illness, we examined the virology of ARTI and determined the clinical impact of virus-virus codetection. Methods. Children aged 6 to 59 months who presented to a tertiary pediatric hospital between influenza seasons 2008 and 2012 with fever and acute respiratory symptoms were enrolled, and nasal samples were collected. Respiratory viruses were identified by culture and polymerase chain reaction. We compared demographics, presenting symptoms, and clinical outcomes of children with a single-virus infection and those in whom 2 or more viruses were detected (virus-virus codetection). We used logistic regression models and estimated marginal means to calculate the adjusted odds ratios and probabilities of symptom presentation, prescription of antibiotics, and hospitalization. Results. Of 2356 children, a virus was detected in 1630 (69.2%) of them; rhinovirus (40.8%), influenza (29.5%), and respiratory syncytial virus (26.4%) were detected most commonly. Two or more viruses were detected in 25% of these children. After we adjusted for demographic factors, children with virus-virus codetection had greater odds of presenting with cough (adjusted odds ratio [aOR], 1.9; 95% confidence interval [CI], 1.2-3.1) and rhinorrhea (aOR, 1.8; 95% CI, 1.1-2.9) than those with a single-virus infection, although both symptoms were common. Children with influenza and respiratory syncytial virus combined had the highest probability of hospitalization (55%; 95% CI, 35%-73%), which was significantly greater than for those with influenza infection alone (22%; 95% CI, 16%-29%). Conclusions. Overall, virus-virus codetection has limited impact on clinical severity among children with influenza-like illness. However, infection with specific pathogen pairs might be associated with more severe outcomes. Routine diagnostics to identify specific viruses should be restricted to common pathogens. [ABSTRACT FROM AUTHOR]

Published
2017
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45. Confidence and Constraint: Public Opinion, Judicial Independence, and the Roberts Court.

Author

Merrill, Alison Higgins, Conway, Nicholas D., and Ura, Joseph Daniel

Subjects
PUBLIC opinion, JUDICIAL independence
Abstract

Although Americans continue to express greater and more stable levels of confidence in the Supreme Court than in Congress or the executive branch of the federal government, the Supreme Court's public standing has fallen steadily over the last fifteen years. A growing body of research in political science and related fields indicates that declining public support undermines judicial independence. To illustrate these effects, we estimate a statistical model of the Supreme Court's propensity to invalidate federal laws on constitutional grounds in each term from 1973 through 2014 and generate predictions of the number of federal laws struck down by the Supreme Court under various political conditions. This analysis shows how the decline in public support during the Roberts Court year has affected the Justices' willingness to invalidate federal laws. We argue that evidence of a link between persistent declines in the Supreme Court's public standing and lost judicial independence suggest that Chief Justice Roberts take a more aggressive public stance as an advocate for the Supreme Court. [ABSTRACT FROM AUTHOR]

Published
2017

48. Die Hard, not Lethal Weapon

Author

Conway, Nicholas

Subjects
Sports, sporting goods and toys industry
Abstract

I enjoyed Mr. Ranch's article discussing how much spare ammo to carry. However, I was a little confused by his example of Bruce Willis in the first Lethal Weapon movie. [...]

Published
2006

49. Clinical Predictors of Influenza in Young Children: The Limitations of “Influenza-Like Illness”.

Author

Conway, Nicholas T., Wake, Zoe V., Richmond, Peter C., Smith, David W., Keil, Anthony D., Williams, Simon, Kelly, Heath, Carcione, Dale, Effler, Paul V., and Blyth, Christopher C.

Subjects
*INFLUENZA, *JUVENILE diseases, *CLINICAL medicine, *LOGISTIC regression analysis, *PUBLIC health surveillance
Abstract

Background Influenza-like illness (ILI) definitions have been infrequently studied in young children. Despite this, clinical definitions of ILI play an important role in influenza surveillance. This study aims to identify clinical predictors of influenza infection in children ≤5 years old from which age-specific ILI definitions are then constructed. Methods Children aged 6–59 months with a history of fever and acute respiratory symptoms were recruited in the Western Australia Influenza Vaccine Effectiveness (WAIVE) Study. Clinical data and per-nasal specimens were obtained from all children. Logistic regression identified significant predictors of influenza infection. Different ILI definitions were compared for diagnostic accuracy. Results Children were recruited from 2 winter influenza seasons (2008–2009; n = 944). Of 919 eligible children, 179 (19.5%) had laboratory-confirmed influenza infection. Predictors of infection included increasing age, lack of influenza vaccination, lower birth weight, fever, cough, and absence of wheeze. An ILI definition comprising fever ≥38°C, cough, and no wheeze had 58% sensitivity (95% confidence interval [CI], 50–66), 60% specificity (95% CI, 56–64), 26% positive predictive value (95% CI, 21–31), and 86% negative predictive value (95% CI, 82–89). The addition of other symptoms or higher fever thresholds to ILI definition had little impact. The Centers for Disease Control and Prevention definition of ILI (presence of fever [≥37.8°C] and cough and/or sore throat) was sensitive (92%; 95% CI, 86–95), yet lacked specificity (10%; 95% CI, 8–13) in this population. Conclusions Influenza-like illness is a poor predictor of laboratory-confirmed influenza infection in young children but can be improved using age-specific data. Incorporating age-specific ILI definitions and/or diagnostic testing into influenza surveillance systems will improve the accuracy of epidemiological data. [ABSTRACT FROM AUTHOR]

Published
2013

50. Kilmacow (B.)

Author

Kilmacow (B.), Loingsigh, P. Ó, Walsh, James, Kinsella, James, Aylward, James, Hearn, Peter, Bolger, James, Connell, John O, Dunne, Lawrence, Conway, Nicholas, Phelan, Edward, Grogan, John, Dunphy, Richard, Coughlan, Willie, Walsh, Thomas, Dunner, Lawrence, Bolger, Martin, Kenneally, M., Walsh, Patrick, Kenneally, Michael, Cassin, Edward, Dunphy, Bernard, Whyte, Thomas, Kinsella, John, Grant, Thomas, Lacey, William, and Donald, James Mac

Subjects
Historic sites, Folk poetry, History, local legends, Kilmacow, Legal status, laws, etc, Cill Mhic Bhúith, Manners and customs, Brigands and robbers, Smithing, narratives, Riddles, Cemeteries, Weather, Gobán Saor (Legendary character), Poverty, Folklore, Treasure troves, legendary creatures, Jokes, Schools, Agriculture, Traditional medicine, Supernatural beings, Banshees, Famine, 1845-1852, Gangs, Dissenters, Religious, Ireland
Abstract

A collection of folklore and local history stories from Kilmacow (B.) (school) (Kilmacow, Co. Kilkenny), collected as part of the Schools' Folklore Scheme, 1937-1938 under the supervision of teacher P. Ó Loingsigh., Crotty the Robber and His Buried Hoard / Walsh, James -- Treasure in Dangan Castle / Kinsella, James -- Robber's Hoard / Aylward, James -- Treasure in Corluddy Castle / Kinsella, James -- Story of Freyney the Robber / Walsh, James -- Tory Hill / Kinsella, James -- St Senan's Well / Hearn, Peter -- Story of Freyney the Robber / Bolger, James -- Story of Móin na Muc / Kinsella, James -- Kilmacow Protestant Church / Walsh, James -- Granagh Castle / Walsh, James -- Tory Hill / Walsh, James -- Story of Páirc Arám / Walsh, James -- How Holly Lake Originated / Kinsella, James -- Fate of the Seven Bishops / Kinsella, James -- Story of the Trunk of Jewels / Walsh, James -- Granagh Castle / Kinsella, James -- Freyney the Robber / Aylward, James -- Giant's Grave / Connell, John O -- Rathkieran Graveyard / Connell, John O -- Black Dog of Kilmokea / Dunne, Lawrence -- Móin na dTrígh gCailín / Aylward, James -- Names of other fields on my father's land are Bán an tSean-Gheaga. / Aylward, James -- Páirc Crimé / Walsh, James -- Story of Holywater / Walsh, James -- Story about Bishopshall / Conway, Nicholas -- Pleasures of a Morning in the Country / Walsh, James -- St Patrick's Visit to Ballinacrea / Phelan, Edward -- The following are sayings about the weather. / Aylward, James -- Black Abbey Kilkenny / Grogan, John -- Páirc Beallach / Walsh, James -- Ancient Headstone / Walsh, James -- Hedge-School / Walsh, James -- Gobán Saor -- Gobán Saor -- Blacksmiths / Walsh, James -- Hangman's Corner / Walsh, James -- Corluddy Castle / Connell, John O -- Funny Story - The Parrot and the Gauger / Connell, John O' -- Páirc na Marbh / Walsh, James -- Seán an tSasanaigh -- Seán an tSasanaigh -- Fate of the Postman -- Tobar na Cille / Dunphy, Richard -- Riddles / Coughlan, Willie -- Weather-Lore / Walsh, James -- Crotty the Robber / Walsh, James -- St Declan's Well / Walsh, Thomas -- Names of Fields / Phelan, Edward -- Sliabh Coillte / Dunne, Lawrence -- Place Names / Dunner, Lawrence -- Riddles / Bolger, Martin -- Old Hedge-School / Walsh, James -- Place Names / Walsh, James -- Weather-Lore / Conway, Nicholas -- Riddles / Conway, Nicholas -- Local Happenings / Walsh, James -- Local Happenings / Walsh, James -- Local Happenings / Walsh, James -- Local Happenings / Walsh, James -- Three Friars / Walsh, James -- Crotty the Robber / Walsh, James -- Mound of Dunkitt / Kenneally, M. -- Fairy Butter / Kenneally, M. -- Jack O' Lantern / Kenneally, M. -- Riddles / Dunphy, Richard -- Ghost Story / Coughlan, Willie -- Irish Prosecution / Walsh, James -- Ghost Story / Walsh, Patrick -- Giant from Tory Hill / Walsh, James -- St David's Well / Kenneally, Michael -- Ghost Story / Cassin, Edward -- Island / Kenneally, Michael -- True Story / Dunphy, Bernard -- True Story / Cassin, Edward -- St Kevin's Well / Walsh, James -- Ghost Story / Whyte, Thomas -- Ghost Story / Kenneally, Michael -- Ghost Story / Whyte, Thomas -- Hiding Place / Dunphy, Bernard -- Witch of Granagh Castle / Dunphy, Bernard -- Ghost Story / Whyte, Thomas -- Ghost Story / Kenneally, Michael -- Funny Story / Dunphy, Richard -- True Ghost Story / Dunphy, Richard -- Story about the Penal Days / Walsh, James -- Old Hedge-School / Walsh, James -- Funny Story / Walsh, James -- Story about Jones's / Walsh, James -- Well / Walsh, James -- True Story / Dunphy, Richard -- Well / Walsh, James -- True Story / Dunphy, Richard -- Saint Fiachra's Well / Dunphy, Bernard -- True Story / Dunphy, Richard -- Story of Years Ago / Dunphy, Bernard -- Story of the Bean Sí / Walsh, Patrick -- Funny Story about a Ghost / Walsh, James -- Story about Fionn Mac Cumhaill / Walsh, James -- Story of the Bean Sí / Aylward, James -- Ghost Story / Kinsella, John -- Ghost Story / Walsh, Patrick -- Ghost Story / Walsh, James -- Blood Field / Walsh, James -- Cures / Phelan, Edward -- Story about a Tailor / Grant, Thomas -- Riddles / Lacey, William -- Three Cornered Field / Dunphy, Richard -- Bean Sí / Walsh, James -- Ghost Story / Donald, James Mac -- Riddles / Donald, James Mac -- Ghost Story / Phelan, Edward -- Funny Stories / Phelan, Edward -- Another One / Phelan, Edward -- Old Song - Kerry Long Ago / Bolger, Martin -- Ghost Story / Dunphy, Bernard -- True Story / Kenneally, Michael -- Riddles / Kenneally, Michael -- Riddles / Conway, Nicholas -- Well / Walsh, James -- Story about a Priest / Walsh, James -- Story of a Strong Man / Aylward, James, Supported by funding from the Department of Arts, Heritage and the Gaeltacht (Ireland), University College Dublin, and the National Folklore Foundation (Fondúireacht Bhéaloideas Éireann), 2014-2016.

Published
1937
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