Author: "Cooper, C. (Charles)" - Searchworks@Jio Institute Digital Library Search Results

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28 results on '"Cooper, C. (Charles)"'

1. Associations of maternal dietary inflammatory potential and quality with offspring birth outcomes: An individual participant data pooled analysis of 7 European cohorts in the ALPHABET consortium

Author: Chen, L.W. (Ling Wei), Aubert, A.M. (Adrien M.), Shivappa, N. (Nitin), Bernard, J.Y. (Jonathan Y.), Mensink-Bout, S.M. (Sara M.), Geraghty, A.A. (Aisling A.), Mehegan, J. (John), Suderman, M.J. (Matthew J.), Polanska, K. (Kinga), Hanke, W. (Wojciech), Trafalska, E. (Elzbieta), Relton, C.L. (Caroline), Crozier, S.R. (Sarah R.), Harvey, N.C. (Nicholas), Cooper, C. (Charles), Duijts, L. (Liesbeth), Heude, B. (Barbara), Hébert, J.R. (James R.), McAuliffe, F.M. (Fionnuala M.), Kelleher, C.C. (Cecily C.), Phillips, C.M. (Catherine M.), Chen, L.W. (Ling Wei), Aubert, A.M. (Adrien M.), Shivappa, N. (Nitin), Bernard, J.Y. (Jonathan Y.), Mensink-Bout, S.M. (Sara M.), Geraghty, A.A. (Aisling A.), Mehegan, J. (John), Suderman, M.J. (Matthew J.), Polanska, K. (Kinga), Hanke, W. (Wojciech), Trafalska, E. (Elzbieta), Relton, C.L. (Caroline), Crozier, S.R. (Sarah R.), Harvey, N.C. (Nicholas), Cooper, C. (Charles), Duijts, L. (Liesbeth), Heude, B. (Barbara), Hébert, J.R. (James R.), McAuliffe, F.M. (Fionnuala M.), Kelleher, C.C. (Cecily C.), and Phillips, C.M. (Catherine M.)
Abstract: BACKGROUND: Adverse birth outcomes are major causes of morbidity and mortality during childhood and associate with a higher risk of noncommunicable diseases in adult life. Maternal periconception and antenatal nutrition, mostly focusing on single nutrients or foods, has been shown to influence infant birth ou
Published: 2021
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2. Development of a polygenic risk score to improve screening for fracture risk: A genetic risk prediction study

Author: Forgetta, V, Keller-Baruch, J., Forest, M., Durand, A., Bhatnagar, S., Kemp, J.P., Nethander, M., Evans, D., Morris, J.A., Kiel, D.P. (Douglas), Rivadeneira Ramirez, F. (Fernando), Johansson, H. (Helena), Harvey, NC, Mellström, D. (Dan), Karlsson, M. (Magnus), Cooper, C. (Charles), Evans, D.M. (David), Clarke, R., Kanis, J.A. (John), Orwoll, E, McCloskey, E.V. (Eugene), Ohlsson, C. (Claes), Pineau, J., Leslie, W.D. (William), Greenwood, J.P. (John), Richards, J.B. (Brent), Forgetta, V, Keller-Baruch, J., Forest, M., Durand, A., Bhatnagar, S., Kemp, J.P., Nethander, M., Evans, D., Morris, J.A., Kiel, D.P. (Douglas), Rivadeneira Ramirez, F. (Fernando), Johansson, H. (Helena), Harvey, NC, Mellström, D. (Dan), Karlsson, M. (Magnus), Cooper, C. (Charles), Evans, D.M. (David), Clarke, R., Kanis, J.A. (John), Orwoll, E, McCloskey, E.V. (Eugene), Ohlsson, C. (Claes), Pineau, J., Leslie, W.D. (William), Greenwood, J.P. (John), and Richards, J.B. (Brent)
Abstract: Background Since screening programs identify only a small proportion of the population as eligible for an intervention, genomic prediction of heritable risk factors could decrease the number needing to be screened by removing individuals at low genetic risk. We therefore tested whether a polygenic risk score for heel quantitative ultrasound speed of sound (SOS)—a heritable risk factor for osteoporotic fracture—can identify low-risk individuals who can safely be excluded from a fracture risk screening program. Methods and findings A polygenic risk score for SOS was trained and selected in 2 separate subsets of UK Biobank (comprising 341,449 and 5,335 individuals). The top-performing prediction model was termed “gSOS”, and its utility in fracture risk screening was tested in 5 validation cohorts using the National Osteoporosis Guideline Group clinical guidelines (N = 10,522 eligible participants). All individuals were genome-wide genotyped and had measured fracture risk factors. Across the 5 cohorts, the average age ranged from 57 to 75 years, and 54% of studied individuals were women. The main outcomes were the sensitivity and specificity to correctly identify individuals requiring treatment with and without genetic prescreening. The reference standard was a bone mineral density (BMD)–based Fracture Risk Assessment Tool (FRAX) score. The secondary outcomes were the proportions of the screened population requiring clinical-risk-factor-based FRAX (CRF-FRAX) screening and BMD-based FRAX (BMDFRAX) screening. gSOS was strongly correlated with measured SOS (r 2 = 23.2%, 95% CI 22.7% to 23.7%). Without genetic prescreening, guideline recommendations achieved a sensitivity and specificity for correct treatment assignment of 99.6% and 97.1%, respectively, in the validation cohorts. However, 81% of the population required CRF-FRAX tests, and 37% required BMD-FRAX tests to achieve this accuracy. Using gS
Published: 2020
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3. Development of a polygenic risk score to improve screening for fracture risk: A genetic risk prediction study

Author: Forgetta, V. (Vincenzo), Keller-Baruch, J. (Julyan), Forest, M. (Marie), Durand, A. (Audrey), Bhatnagar, S. (Sahir), Kemp, J.P. (John), Nethander, M. (Maria), Evans, D.S. (Daniel), Morris, J.A. (John A.), Kiel, D.P. (Douglas P.), Rivadeneira Ramirez, F. (Fernando), Johansson, H. (Helena), Harvey, N.C. (Nicholas), Mellström, D. (Dan), Karlsson, M. (Magnus), Cooper, C. (Charles), Evans, D.M. (David M.), Clarke, R. (Robert), Kanis, J.A. (John), Orwoll, E.S. (Eric), McCloskey, E.V. (Eugene), Ohlsson, C. (Claes), Pineau, J. (Joelle), Leslie, W.D. (William D.), Greenwood, C.M.T. (Celia M T), Richards, J.B. (J Brent), Forgetta, V. (Vincenzo), Keller-Baruch, J. (Julyan), Forest, M. (Marie), Durand, A. (Audrey), Bhatnagar, S. (Sahir), Kemp, J.P. (John), Nethander, M. (Maria), Evans, D.S. (Daniel), Morris, J.A. (John A.), Kiel, D.P. (Douglas P.), Rivadeneira Ramirez, F. (Fernando), Johansson, H. (Helena), Harvey, N.C. (Nicholas), Mellström, D. (Dan), Karlsson, M. (Magnus), Cooper, C. (Charles), Evans, D.M. (David M.), Clarke, R. (Robert), Kanis, J.A. (John), Orwoll, E.S. (Eric), McCloskey, E.V. (Eugene), Ohlsson, C. (Claes), Pineau, J. (Joelle), Leslie, W.D. (William D.), Greenwood, C.M.T. (Celia M T), and Richards, J.B. (J Brent)
Abstract: BACKGROUND: Since screening programs identify only a small proportion of the population as eligible for an intervention, genomic prediction of heritable risk factors could decrease the number needing to be screened by removing individuals at low genetic risk. We therefore tested whether a polygenic risk score for heel quantitative ultrasound speed of sound (SOS)-a heritable risk factor for osteoporotic fracture-can identify low-risk individuals who can safely be excluded from a fracture risk screening program. METHODS AND FINDINGS: A polygenic risk score for SOS was trained and selected in 2 separate subsets of UK Biobank (comprising 341,449 and 5,335 individuals). The top-performing prediction model was termed "gSOS", and its utility in fracture risk scre
Published: 2020
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4. Repositioning of the global epicentre of non-optimal cholesterol

Author: Taddei, C. (Cristina), Zhou, B. (Bin), Bixby, H. (Honor), Carrillo-Larco, R.M. (Rodrigo M.), Danaei, G. (Goodarz), Jackson, R.T. (Rod T.), Farzadfar, F. (Farshad), Sophiea, M.K. (Marisa K.), Di Cesare, M. (Mariachiara), Iurilli, M.L.C. (Maria Laura Caminia), Martinez, A.R. (Andrea Rodriguez), Asghari, G. (Golaleh), Dhana, K. (Klodian), Gulayin, P. (Pablo), Kakarmath, S. (Sujay), Santero, M. (Marilina), Voortman, R.G. (Trudy), Riley, L.M. (Leanne M.), Cowan, M.J. (Melanie J.), Savin, S. (Stefan), Bennett, J.E. (James E.), Stevens, G.A. (Gretchen A.), Paciorek, C.J. (Christopher J.), Aekplakorn, W. (Wichai), Cifkova, R. (Renata), Giampaoli, S. (Simona), Kengne, A.P. (Andre Pascal), Khang, Y.-H. (Young-Ho), Kuulasmaa, K. (Kari), Laxmaiah, A. (Avula), Margozzini, P. (Paula), Mathur, P. (Prashant), Nordestgaard, B.G. (Børge), Zhao, D. (Dong), Aadahl, M. (Mette), Abarca-Gómez, L. (Leandra), Rahim, H.A. (Hanan Abdul), Abu-Rmeileh, N.M. (Niveen M.), Acosta-Cazares, B. (Benjamin), Adams, R.J. (Robert J.), Agdeppa, I.A. (Imelda A.), Aghazadeh-Attari, J. (Javad), Aguilar-Salinas, C.A. (Carlos A.), Agyemang, C.O. (Charles), Ahluwalia, T.S. (Tarunveer Singh), Ahmad, N.A. (Noor Ani), Ahmadi, A. (Ali), Ahmadi, N. (Naser), Ahmed, S.H. (Soheir H.), Ahrens, W. (W.), Ajlouni, K. (Kamel), Alarouj, M. (Monira), AlBuhairan, F. (Fadia), AlDhukair, S. (Shahla), Ali, M.M. (Mohamed M.), Alkandari, A. (Abdullah), Alkerwi, A. (Ala’a), Aly, E. (Eman), Amarapurkar, D.N. (Deepak N.), Amouyel, P. (Philippe), Andersen, L.B. (Lars Bo), Anderssen, S.A. (Sigmund A.), Anjana, R.M. (Ranjit Mohan), Ansari-Moghaddam, A. (Alireza), Aounallah-Skhiri, H. (Hajer), Araújo, J. (Joana), Ariansen, I. (Inger), Aris, T. (Tahir), Arku, R.E. (Raphael E.), Arlappa, N. (Nimmathota), Aryal, K.K. (Krishna K.), Aspelund, T. (Thor), Assunção, M.C.F. (Maria Cecília F.), Auvinen, J. (Juha), Avdicová, M. (Mária), Azevedo, A. (Ana), Azizi, J. (Joshan), Azmin, M. (Mehrdad), Balakrishna, N. (Nagalla), Bamoshmoosh, M. (Mohamed), Banach, M. (Maciej), Bandosz, P. (Piotr), Banegas, J.R. (José R.), Barbagallo, C.M. (Carlo M.), Barceló, A. (Alberto), Barkat, A. (Amina), Bata, I. (Iqbal), Batieha, A.M. (Anwar M.), Batyrbek, A. (Assembekov), Baur, L.A. (Louise A.), Beaglehole, R. (Robert), Belavendra, A. (Antonisamy), Ben Romdhane, H. (Habiba), Benet, M. (Mikhail), Benn, M. (Marianne), Berkinbayev, S. (Salim), Bernabe-Ortiz, A. (Antonio), Bernotiene, G. (Gailute), Bettiol, H. (Heloisa), Bhargava, S.K. (Santosh K.), Bi, Y. (Yufang), Bienek, A. (Asako), Bikbov, M. (Mukharram), Bista, B. (Bihungum), Bjerregaard, P. (Peter), Bjertness, E. (Espen), Bjertness, M.B. (Marius B.), Björkelund, C. (Cecilia), Bloch, K.V. (Katia V.), Blokstra, A. (Anneke), Bo, S. (Simona), Boehm, B.O. (Bernhard O.), Boggia, J.G. (Jose G.), Boissonnet, C.P. (Carlos P.), Bonaccio, M. (Marialaura), Bongard, V. (Vanina), Borchini, R. (Rossana), Borghs, H. (Herman), Bovet, P. (Pascal), Brajkovich, I. (Imperia), Breckenkamp, J. (Juergen), Brenner, H. (Hermann), Brewster, L.M. (Lizzy), Bruno, G. (Graziella), Bugge, A. (Anna), Busch, M.A. (Markus A.), de León, A.C. (Antonio Cabrera), Cacciottolo, J. (Joseph), Can, G. (Günay), Cândido, A.P.C. (Ana Paula C.), Capanzana, M.V. (Mario V.), Capuano, E. (Eduardo), Capuano, V. (Vincenzo), Cardoso, V.C. (Viviane C.), Carvalho, J. (Joana), Casanueva, F.F., Censi, L. (Laura), Chadjigeorgiou, C.A. (Charalambos A.), Chamukuttan, S. (Snehalatha), Chaturvedi, N. (Nish), Chen, C.-J. (Chien-Jen), Chen, F. (Fangfang), Chen, S. (Shuohua), Cheng, C.-Y. (Ching-Yu), Cheraghian, B. (Bahman), Chetrit, A. (Angela), Chiou, S.-T. (Shu-Ti), Chirlaque, M.D. (M.), Cho, B. (Belong), Cho, Y. (Yumi), Chudek, J. (Jerzy), Claessens, F. (Frank), Clarke, J. (Janine), Clays, E. (Els), Concin, H. (Hans), Confortin, S.C. (Susana C.), Cooper, C. (Charles), Costanzo, S. (Simona), Cottel, D. (Dominique), Cowell, C. (Chris), Crujeiras, A.B. (Ana B.), Csilla, S. (Semánová), Cui, L. (Liufu), Cureau, F.V. (Felipe V.), D’Arrigo, G. (Graziella), d’Orsi, E. (Eleonora), Dallongeville, J., Damasceno, A. (Albertino), Dankner, R. (Rachel), Dantoft, T.M. (Thomas M.), Dauchet, L. (Luc), Davletov, K. (Kairat), Backer, G. (Guy) de, Bacquer, D. (Dirk) de, de Gaetano, G. (Giovanni), De Henauw, S. (Stefaan), de Oliveira, P.D. (Paula Duarte), De Ridder, D. (David), De Smedt, D. (Delphine), Deepa, M. (Mohan), Deev, A.D. (Alexander D.), Dehghan, A. (Abbas), Delisle, H. (Hélène), Dennison, E.M. (Elaine), Deschamps, V. (Valérie), Dhimal, M. (Meghnath), Di Castelnuovo, A.F. (Augusto F.), Dika, Z. (Zivka), Djalalinia, S. (Shirin), Dobson, A.J. (Annette J.), Donfrancesco, C. (Chiara), Donoso, S.P. (Silvana P.), Döring, A. (Angela), Dorobantu, M. (Maria), Dragano, N. (Nico), Drygas, W. (Wojciech), Du, Y. (Yong), Duante, C.A. (Charmaine A.), Duda, R.B. (Rosemary B.), Dzerve, V. (Vilnis), Dziankowska-Zaborszczyk, E. (Elzbieta), Eddie, R. (Ricky), Eftekhar, E. (Ebrahim), Eggertsen, R. (Robert), Eghtesad, S. (Sareh), Eiben, G. (Gabriele), Ekelund, U. (Ulf), El Ati, J. (Jalila), Eldemire-Shearer, D. (Denise), Eliasen, M. (Marie), Elosua, R. (Roberto), Erasmus, R.T. (Rajiv T.), Erbel, R. (Raimund), Erem, C. (Cihangir), Eriksen, L. (Louise), Hagen, K. (Knut), Escobedo-de la Peña, J. (Jorge), Eslami, S. (Saeid), Esmaeili, A. (Ali), Evans, A. (Alun), Faeh, D. (David), Fall, C.H. (Caroline H.), Faramarzi, E. (Elnaz), Farjam, M. (Mojtaba), Fattahi, M.R. (Mohammad Reza), Felix-Redondo, F.J. (Francisco J.), Ferguson, T.S. (Trevor S.), Fernández-Bergés, D. (Daniel), Ferrante, D. (Daniel), Ferrari, M. (Marika), Ferreccio, C. (Catterina), Ferrieres, J. (Jean), Föger, B. (Bernhard), Foo, L.H. (Leng Huat), Forslund, A.-S. (Ann-Sofie), Forsner, M. (Maria), Fouad, H.M. (Heba M.), Francis, D.K. (Damian K.), do Carmo Franco, M. (Maria), Franco, O.H. (Oscar H.), Frontera, G. (Guillermo), Fujita, Y. (Yuki), Fumihiko, M. (Matsuda), Furusawa, T. (Takuro), Gaciong, Z. (Zbigniew), Galvano, F. (Fabio), Gao, J. (Jingli), Garcia-de-la-Hera, M. (Manoli), Garnett, S.P. (Sarah P.), Gaspoz, J.-M. (Jean-Michel), Gasull, M. (Magda), Gazzinelli, A. (Andrea), Geleijnse, J.M. (Marianne), Ghanbari, A. (Ali), Ghasemi, E. (Erfan), Gheorghe-Fronea, O.-F. (Oana-Florentina), Ghimire, A. (Anup), Gianfagna, F. (Francesco), Gill, T.K. (Tiffany K.), Giovannelli, J. (Jonathan), Gironella, G. (Glen), Giwercman, A. (Aleksander), Goltzman, D. (David), Gonçalves, H. (Helen), Gonzalez-Chica, D.A. (David A.), Gonzalez-Gross, M. (Marcela), González-Rivas, J.P. (Juan P.), González-Villalpando, C. (Clicerio), González-Villalpando, M.E. (María Elena), Gonzalez, A.R. (Angel R.), Gottrand, F., Graff-Iversen, S. (Sidsel), Grafnetter, D. (Dušan), Gregor, R.D. (Ronald D.), Grodzicki, T. (Tomasz), Grøntved, A. (Anders), Grosso, G. (Giuseppe), Gruden, G. (Gabriella), Gu, D. (Dongfeng), Guallar-castillón, P. (Pilar), Guan, O.P. (Ong Peng), Gudmundsson, E.F. (Elias F.), Gudnason, V. (Vilmundur), Guerrero, R. (Ramiro), Guessous, I. (Idris), Gunnlaugsdottir, J. (Johanna), Gupta, R. (Rajeev), Gutierrez, L. (Laura), Gutzwiller, F. (Felix), Ha, S. (Seongjun), Hadaegh, F. (Farzad), Haghshenas, R. (Rosa), Hakimi, H. (Hamid), Hambleton, I.R. (Ian R.), Hamzeh, B. (Behrooz), Hantunen, S. (Sari), Kumar, R.H. (Rachakulla Hari), Hashemi-Shahri, S.M. (Seyed Mohammad), Hata, J. (Jun), Haugsgjerd, T. (Teresa), Hayes, A.J. (Alison J.), He, J. (Jiang), He, Y. (Yong), Hendriks, M.E. (Marleen), Henriques, A. (Ana), Herrala, S. (Sauli), Heshmat, R. (Ramin), Hill, A.G. (Allan G.), Ho, S.Y. (Sai Yin), Ho, S.C. (Suzanne C.), Hobbs, M. (Michael), Hofman, A. (Albert), Homayounfar, R. (Reza), Hopman, W.M. (Wilma M.), Horimoto, A.R.V.R. (Andrea R. V. R.), Hormiga, C.M. (Claudia M.), Horta, B.L. (Bernardo L.), Houti, L. (Leila), Howitt, C. (Christina), Htay, T.T. (Thein Thein), Htet, A.S. (Aung Soe), Htike, M.M.T. (Maung Maung Than), Huerta, J.M. (José María), Huhtaniemi, I.T. (I.), Huisman, M. (Martijn), Hunsberger, M.L. (Monica L.), Husseini, A. (Abdullatif), Huybrechts, I. (Inge), Hwalla, N. (Nahla), Iacoviello, L. (Licia), Iannone, A.G. (Anna G.), Ibrahim, M.M. (Mohsen), Wong, N.I. (Norazizah Ibrahim), Iglesia, I. (Iris), Ikeda, N. (Nayu), Ikram, M.A. (Arfan), Iotova, V. (Violeta), Irazola, V.E. (Vilma E.), Ishida, T. (Takafumi), Islam, M. (Muhammad), al-Safi Ismail, A. (Aziz), Iwasaki, M. (Masanori), Jacobs, J.M. (Jeremy M.), Jaddou, H.Y. (Hashem Y.), Jafar, T.H. (Tazeen), James, K. (Kenneth), Jamrozik, K., Janszky, I. (Imre), Janus, E. (Edward), Jarvelin, M.-R. (Marjo-Riitta), Jasienska, G. (Grazyna), Jelakovic, A. (Ana), Jelakovic, B. (Bojan), Jennings, G. (Garry), Jensen, G.B. (Gorm), Jeong, S.-L. (Seung-lyeal), Jha, A.K. (Anjani Kumar), Jiang, C.Q. (Chao Qiang), Jimenez, R.O. (Ramon O.), JöCkel, K.-H. (Karl-Heinz), Joffres, M. (Michel), Jokelainen, J.J. (Jari J.), Jonas, J.B. (Jost B.), Jorgensen, T. (Torben), Joshi, P. (Pradeep), Joukar, F. (Farahnaz), Józwiak, J. (Jacek), Juolevi, A. (Anne), Kafatos, A. (Anthony), Kajantie, E. (Eero), Kalter-Leibovici, O. (Ofra), Kamaruddin, N.A. (Nor Azmi), Kamstrup, P.R. (Pia R.), Karki, K.B. (Khem B.), Katz, J. (Joanne), Kauhanen, J. (Jussi), Kaur, P. (Prabhdeep), Kavousi, M. (Maryam), Kazakbaeva, G. (Gyulli), Keil, M. (Mark), Keinanen-Kiukaanniemi, S. (Sirkka), Kelishadi, R. (Roya), Keramati, M. (Maryam), Kerimkulova, A. (Alina), Kersting, M. (Mathilde), Khader, Y.S. (Yousef Saleh), Khalili, D. (Davood), Khateeb, M. (Mohammad), Kheradmand, M. (Motahareh), Khosravi, A. (Alireza), Kiechl-Kohlendorfer, U. (Ursula), Kiechl, S. (Stefan), Killewo, J. (Japhet), Kim, H.C. (Hyeon Chang), Kim, J. (Jeongseon), Kim, Y.-Y. (Yeon-Yong), Klumbiene, J. (Jurate), Knoflach, M. (Michael), Ko, S. (Stephanie), Kohler, H.-P. (Hans-Peter), Kohler, I.V. (Iliana V.), Kolle, E. (Elin), Kolsteren, P. (Patrick), König, J. (Jürgen), Korpelainen, R. (Raija), Korrovits, P. (Paul), Kos, J. (Jelena), Koskinen, S. (Seppo), Kouda, K. (Katsuyasu), Kowlessur, S. (Sudhir), Kratzer, W. (Wolfgang), Kriemler, S. (Susi), Kristensen, P.L. (Peter Lund), Krokstad, S. (Steiner), Kromhout, D. (Daan), Kujala, U.M. (Urho), Kurjata, P. (Pawel), Kyobutungi, C. (Catherine), Laamiri, F.Z. (Fatima Zahra), Laatikainen, T. (Tiina), Lachat, C. (Carl), Laid, Y. (Youcef), Lam, T.H. (Tai Hing), Lambrinou, C.-P. (Christina-Paulina), Lanska, V. (Vera), Lappas, G. (Georg), Larijani, B. (Bagher), Latt, T.S. (Tint Swe), Laugsand, L.E. (Lars E.), Lazo-Porras, M. (Maria), Lee, J. (Jeannette), Lee, J. (Jeonghee), Lehmann, N. (Nils), Lehtimäki, T. (Terho), Levitt, N.S. (Naomi S.), Li, Y. (Yanping), Lilly, C.L. (Christa L.), Lim, W.-Y. (Wei-Yen), Lima-Costa, M.F. (Maria Fernanda), Lin, H.-H. (Hsien-Ho), Lin, X. (Xu), Lin, Y.-T. (Yi-Ting), Kao, W.H.L. (Wen), Linneberg, A. (Allan), Lissner, L. (Lauren), Liu, J. (Jing), Loit, H.-M. (Helle-Mai), Lopez-Garcia, E. (Esther), Lopez, T. (Tania), Lotufo, P.A. (Paulo A), Lozano, J.E. (José Eugenio), Luksiene, D. (Dalia), Lundqvist, A. (Annamari), Lundqvist, R. (Robert), Lunet, N. (Nuno), Ma, G. (Guansheng), Machado-Coelho, G.L.L. (George L. L.), Machado-Rodrigues, A.M. (Aristides M.), Machi, S. (Suka), Madar, A.A. (Ahmed A.), Maggi, S. (Stefania), Magliano, D.J., Magriplis, E. (Emmanuella), Mahasampath, G. (Gowri), Maire, B. (Bernard), Makdisse, M. (Marcia), Malekzadeh, F. (Fatemeh), Malekzadeh, R. (Reza), Rao, K.M. (Kodavanti Mallikharjuna), Manios, Y., Mann, J.I. (Jim I.), Mansour-Ghanaei, F. (Fariborz), Manzato, E. (Enzo), Marques-Vidal, P. (Pedro), Martorell, R. (Reynaldo), Mascarenhas, L.P. (Luis P.), Mathiesen, E.B. (Ellisiv), Matsha, T.E. (Tandi E.), Mavrogianni, C. (Christina), McFarlane, S.R. (Shelly R.), McGarvey, S.T. (Stephen T.), McLachlan, S. (Stela), McLean, R.M. (Rachael M.), McLean, S.B. (Scott B.), McNulty, B.A. (Breige A.), Mediene-Benchekor, S. (Sounnia), Mehdipour, P. (Parinaz), Mehlig, K. (Kirsten), Mehrparvar, A.H. (Amir Houshang), Meirhaeghe, A. (Aline), Meisinger, C. (Christa), Menezes, A.M.B. (Ana M.B.), Menon, G.R. (Geetha R.), Merat, S. (Shahin), Mereke, A. (Alibek), Meshram, I.I. (Indrapal I.), Metcalf, P. (Patricia), Meyer, H.E. (Haakon E.), Mi, J. (Jie), Michels, N. (Nathalie), Miller, J.C. (Jody C.), Minderico, C.S. (Cláudia S.), Mini, G.K. (G. K.), Miquel, J.F. (Juan Francisco), Miranda, J.J. (J. Jaime), Mirjalili, M.R. (Mohammad Reza), Mirrakhimov, E. (Erkin), Modesti, P.A. (Pietro A.), Moghaddam, S.S. (Sahar Saeedi), Mohajer, B. (Bahram), Mohamed, M.K. (Mostafa K.), Mohammad, K. (Kazem), Mohammadi, Z. (Zahra), Mohammadifard, N. (Noushin), Mohammadpourhodki, R. (Reza), Mohan, V. (Viswanathan), Mohanna, S. (Salim), Yusoff, M.F.M. (Muhammad Fadhli Mohd), Mohebbi, I. (Iraj), Mohebi, F. (Farnam), Moitry, M. (Marie), Møllehave, L.T. (Line T.), Møller, N.C. (Niels C.), Molnár, D. (Dénes), Momenan, A. (Amirabbas), Mondo, C.K. (Charles K.), Monterrubio-Flores, E. (Eric), Moosazadeh, M. (Mahmood), Morejon, A. (Alain), Moreno, L. (Luis), Morgan, K. (Karen), Morin, S.N. (Suzanne N.), Moschonis, G. (George), Mossakowska, M. (Malgorzata), Mostafa, A. (Aya), Mota, J. (Jorge), Motlagh, M.E. (Mohammad Esmaeel), Motta, J. (Jorge), Msyamboza, K.P. (Kelias P.), Muiesan, M.L. (Maria Lorenza), Müller-Nurasyid, M. (Martina), Mursu, J. (Jaakko), Mustafa, N. (Norlaila), Nabipour, I. (Iraj), Naderimagham, S. (Shohreh), Nagel, G. (Gabriele), Naidu, B.M. (Balkish M.), Najafi, F. (Farid), Nakamura, H. (Harunobu), Námešná, J. (Jana), Nang, E.E.K. (Ei Ei K.), Nangia, V.B. (Vinay B.), Nauck, M. (Matthias), Neal, W.A. (William A.), Nejatizadeh, A. (Azim), Nenko, I. (Ilona), Nervi, F. (Flavio), Nguyen, N.D. (Nguyen D.), Nguyen, Q.N. (Quang Ngoc), Nieto-Martínez, R.E. (Ramfis E.), Nihal, T. (Thomas), Niiranen, T.J. (Teemu J.), Ning, G. (Guang), Ninomiya, T. (Toshiharu), Noale, M. (Marianna), Noboa, O.A. (Oscar A.), Noto, D. (Davide), Nsour, M.A. (Mohannad Al), Nuhoğlu, I. (Irfan), O’Neill, T.W. (Terence W.), O’Reilly, D. (Dermot), Ochoa-Avilés, A.M. (Angélica M.), Oh, K. (Kyungwon), Ohtsuka, R. (Ryutaro), Olafsson, Ö. (Örn), Olié, V. (Valérie), Oliveira, I.O. (Isabel O.), Omar, M.A. (Mohd Azahadi), Onat, A. (Altan), Ong, S.K. (Sok King), Ordunez, P. (Pedro), Ornelas, R. (Rui), Ortiz, P.J. (Pedro J.), Osmond, C. (Clive), Ostojic, S.M. (Sergej M.), Ostovar, A. (Afshin), Otero, J.A. (Johanna A.), Owusu-Dabo, E. (Ellis), Paccaud, F.M. (Fred Michel), Pahomova, E. (Elena), Pajak, A. (Andrzej), Palmieri, L. (Luigi), Pan, W.-H. (Wen-Harn), Panda-Jonas, S. (Songhomitra), Panza, F. (Francesco), Parnell, W.R. (Winsome R.), Patel, N.D. (Nikhil D.), Peer, N. (Nasheeta), Peixoto, S.V. (Sergio Viana), Peltonen, M. (Markku), Pereira, A. (A.), Peters, A. (Annette), Petersmann, A. (Astrid), Petkeviciene, J. (Janina), Peykari, N. (Niloofar), Pham, S.T. (Son Thai), Pichardo, R.N. (Rafael N.), Pigeot, I. (Iris), Pilav, A. (Aida), Pilotto, A. (Alberto), Piwonska, A. (Aleksandra), Pizarro, A.N. (Andreia N.), Plans-Rubió, P. (Pedro), Plata, S. (Silvia), Pohlabeln, H. (Hermann), Porta, M. (Miquel), Portegies, M.L.P. (Marileen), Poudyal, A. (Anil), Pourfarzi, F. (Farhad), Poustchi, H. (Hossein), Pradeepa, R. (Rajendra), Price, J.F. (Jacqueline F.), Providencia, R. (Rui), Puder, J.J. (Jardena J.), Puhakka, S.E. (Soile E.), Punab, M. (Margus), Qorbani, M. (Mostafa), Bao, T.Q. (Tran Quoc), Radisauskas, R. (Ricardas), Rahimikazerooni, S. (Salar), Raitakari, O. (Olli), Rao, S.R. (Sudha Ramachandra), Ramachandran, A. (Ambady), Ramos, E. (Elisabete), Ramos, R. (Rafel), Rampal, L. (Lekhraj), Rampal, S. (Sanjay), Redón, J. (Josep), Reganit, P.F.M. (Paul Ferdinand M.), Revilla, L. (Luis), Rezaianzadeh, A. (Abbas), Ribeiro, R. (Robespierre), Richter, A. (Adrian), Rigo, F. (Fernando), Rinke de Wit, T.F. (Tobias), Rodríguez Artalejo, F. (Fernando), del Cristo Rodriguez-Perez, M. (María), Rodríguez-Villamizar, L.A. (Laura A.), Roggenbuck, U. (Ulla), Rojas-Martinez, R. (Rosalba), Romaguera, D. (Dora), Romeo, E.L. (Elisabetta L.), Rosengren, A. (Annika), Roy, J.G.R. (Joel G. R.), Rubinstein, A. (Adolfo), Ruidavets, J.-B. (Jean-Bernard), Ruiz-Betancourt, B.S. (Blanca Sandra), Russo, P. (Paola), Rust, P. (Petra), Rutkowski, M. (Marcin), Sabanayagam, C. (Charumathi), Sachdev, H.S. (Harshpal S.), Sadjadi, A. (Alireza), Safarpour, A.R. (Ali Reza), Safiri, S. (Saeid), Saidi, O. (Olfa), Saki, N. (Nader), Salanave, B. (Benoit), Salmerón, D. (Diego), Salomaa, V. (Veikko), Salonen, J.T. (Jukka T.), Salvetti, M. (Massimo), Sánchez-Abanto, J. (Jose), Sans, S. (Susana), Santaliestra-Pasías, A.M. (Alba M.), Santos, D.A. (Diana A.), Santos, M.P. (Maria Paula), Santos, R. (Rute), Saramies, J.L. (Jouko L.), Sardinha, L.B. (Luis B.), Sarrafzadegan, N. (Nizal), Saum, K.-U. (Kai-Uwe), Savva, S., Sawada, N. (Norie), Sbaraini, M. (Mariana), Scazufca, M. (Marcia), Schaan, B.D. (Beatriz D.), Schargrodsky, H. (Herman), Scheidt-Nave, C. (C.), Schienkiewitz, A. (Anja), Schipf, S. (Sabine), Schmidt, C.O. (Carsten O.), Schöttker, B. (Ben), Schramm, S. (Sara), Sebert, S. (Sylvain), Sein, A.A. (Aye Aye), Sen, A. (Abhijit), Sepanlou, S.G. (Sadaf G), Servais, J. (Jennifer), Shakeri, R. (Ramin), Shalnova, S.A. (Svetlana A.), Shamah-Levy, T. (Teresa), Sharafkhah, M. (Maryam), Sharma, S.K. (Sanjib K.), Shaw, J.E., Shayanrad, A. (Amaneh), Shi, Z. (Zumin), Shibuya, K. (Kenji), Shimizu-Furusawa, H. (Hana), Shin, D.W. (Dong Wook), Shin, Y. (Youchan), Shirani, M. (Majid), Shiri, R. (Rahman), Shrestha, N. (Namuna), Si-Ramlee, K. (Khairil), Siani, A. (Alfonso), Siantar, R. (Rosalynn), Sibai, A.M. (Abla M.), Silva, D.A.S. (Diego Augusto Santos), Simon, M. (Mary), Simons, J. (Judith), Simons, L.A. (Leon A.), Sjöström, M. (Michael), Skaaby, T. (Tea), Slowikowska-Hilczer, J. (Jolanta), Slusarczyk, P. (Przemyslaw), Smeeth, L. (Liam), Snijder, M.B. (Marieke), Söderberg, S. (Stefan), Soemantri, A. (Augustinus), Sofat, R. (Reecha), Solfrizzi, V. (Vincenzo), Somi, M.H. (Mohammad Hossein), Sonestedt, E. (Emily), Sørensen, T.I.A. (Thorkild), Jérome, C.S. (Charles Sossa), Soumaré, A. (Aicha), Sozmen, K. (Kaan), Sparrenberger, K. (Karen), Staessen, J.A. (Jan), Stathopoulou, M.G. (Maria G), Stavreski, B. (Bill), Steene-Johannessen, J. (Jostein), Stehle, P. (Peter), Stein, A.D. (Aryeh D.), Stessman, J. (Jochanan), Stevanović, R. (Ranko), Stieber, J. (Jutta), Stöckl, D. (Doris), Stokwiszewski, J. (Jakub), Stronks, K. (Karien), Strufaldi, M.W. (Maria Wany), Suárez-Medina, R. (Ramón), Sun, C.-A. (Chien-An), Sundström, J. (Johan), Suriyawongpaisal, P. (Paibul), Sy, R.G. (Rody G.), Sylva, R.C. (René Charles), Szklo, M. (Moyses), Tai, E.S. (Shyong), Tamosiunas, A. (Abdonas), Tan, E.J. (Eng Joo), Tarawneh, M.R. (Mohammed Rasoul), Tarqui-Mamani, C.B. (Carolina B.), Taylor, A. (Anne), Taylor, J. (Julie), Tell, G.S. (Grethe S.), Tello, T. (Tania), Thankappan, K.R. (K. R.), Thijs, L. (Lutgarde), Thuesen, B.H. (Betina H.), Toft, U. (Ulla), Tolonen, H.K. (Hanna K.), Tolstrup, J.S. (Janne), Topbas, M. (Murat), Topór-Madry, R. (Roman), Tormo, M.J., Tornaritis, M.J. (Michael J.), Torrent, M. (Maties), Torres-Collado, L. (Laura), Traissac, P. (Pierre), Trinh, O.T.H. (Oanh T. H.), Truthmann, J. (Julia), Tsugane, S. (Shoichiro), Tulloch-Reid, M.K. (Marshall K.), Tuomainen, T.-P. (Tomi-Pekka), Tuomilehto, J. (Jaakko), Tybjaerg-Hansen, A. (Anne), Tzourio, C. (Christophe), Ueda, P. (Peter), Ugel, E. (Eunice), Ulmer, H. (Hanno), Unal, B. (Belgin), Uusitalo, H., Valdivia, G. (Gonzalo), Valvi, D. (Damaskini), Dam, R.M. (Rob) van, Schouw, Y.T. (Yvonne) van der, Van Herck, K. (Koen), Van Minh, H. (Hoang), Rossem, L. (Lenie) van, Schoor, N.M. (Natasja) van, Valkengoed, I. (Irene) van, Vanderschueren, D. (Dirk), Vanuzzo, D. (Diego), Varbo, A. (Anette), Varona-Pérez, P. (Patricia), Vasan, S.K. (Senthil K.), Vatten, L. (Lars), Vega, T. (Tomas), Veidebaum, T. (Toomas), Velasquez-Melendez, G. (Gustavo), Venero-Fernández, S.J. (Silvia J.), Veronesi, G. (Giovanni), Verschuren, W.M.M. (W. M. Monique), Victora, C.G. (Cesar G.), Vidiawati, D. (Dhanasari), Viet, L. (Lucie), Villalpando, S. (Salvador), Vioque, J. (Jesus), Virtanen, J.K. (Jyrki K.), Visvikis-Siest, S. (Sophie), Viswanathan, B. (Bharathi), Vlasoff, T. (Tiina), Vollenweider, P. (Peter), Voutilainen, A. (Ari), Wade, A.N. (Alisha N.), Wagner, A. (Aline), Walton, J. (Janette), Bebakar, W.M.W. (Wan Mohamad Wan), Mohamud, W.N.W. (Wan Nazaimoon Wan), Wang, M.-D. (Ming-Dong), Wang, N. (Ningli), Wang, Q. (Qian), Wang, Y.X. (Ya Xing), Wang, Y.-W. (Ying-Wei), Wannamethee, S.G. (Goya), Wedderkopp, N. (Niels), Wei, W. (Wenbin), Whincup, P.H. (Peter), Widhalm, K. (Kurt), Widyahening, I.S. (Indah S.), Wiecek, A. (Andrzej), Wijga, A.H. (Alet), Wilks, R.J. (Rainford J.), Willeit, J. (Johann), Willeit, P. (Peter), Wilsgaard, T. (Tom), Wojtyniak, B. (Bogdan), Wong-McClure, R.A. (Roy A.), Wong, A. (Andrew), Wong, T.Y. (Tien Yin), Woo, J. (Jean), Woodward, M. (Mark), Wu, F.C. (Frederick C.), Wu, S. (Shouling), Xu, H. (Haiquan), Xu, L. (Liang), Yan, W. (Weili), Yang, X. (Xiaoguang), Yasuharu, T. (Tabara), Ye, X. (Xingwang), Yeow, T.P. (Toh Peng), Yiallouros, P.K. (P.), Yoosefi, M. (Moein), Yoshihara, A. (Akihiro), You, S.-L. (San-Lin), Younger-Coleman, N.O. (Novie O.), Yusoff, A.F. (Ahmad Faudzi), Zainuddin, A.A. (Ahmad A.), Zakavi, S.R. (Seyed Rasoul), Zali, M.R. (Mohammad Reza), Zamani, F. (Farhad), Zambon, S. (Sabina), Zampelas, A. (Antonis), Zaw, K.K. (Ko Ko), Zdrojewski, T. (T.), Vrkic, T.Z. (Tajana Zeljkovic), Zhang, Z.-Y. (Zhen-Yu), Zhao, W. (Wenhua), Zhen, S. (Shiqi), Zheng, Y. (Yingfeng), Zholdin, B. (Bekbolat), Zhussupov, B. (Baurzhan), Zoghlami, N. (Nada), Cisneros, J.Z. (Julio Zuñiga), Gregg, E.W. (Edward W.), Ezzati, M. (Majid), Taddei, C. (Cristina), Zhou, B. (Bin), Bixby, H. (Honor), Carrillo-Larco, R.M. (Rodrigo M.), Danaei, G. (Goodarz), Jackson, R.T. (Rod T.), Farzadfar, F. (Farshad), Sophiea, M.K. (Marisa K.), Di Cesare, M. (Mariachiara), Iurilli, M.L.C. (Maria Laura Caminia), Martinez, A.R. (Andrea Rodriguez), Asghari, G. (Golaleh), Dhana, K. (Klodian), Gulayin, P. (Pablo), Kakarmath, S. (Sujay), Santero, M. (Marilina), Voortman, R.G. (Trudy), Riley, L.M. (Leanne M.), Cowan, M.J. (Melanie J.), Savin, S. (Stefan), Bennett, J.E. (James E.), Stevens, G.A. (Gretchen A.), Paciorek, C.J. (Christopher J.), Aekplakorn, W. (Wichai), Cifkova, R. (Renata), Giampaoli, S. (Simona), Kengne, A.P. (Andre Pascal), Khang, Y.-H. (Young-Ho), Kuulasmaa, K. (Kari), Laxmaiah, A. (Avula), Margozzini, P. (Paula), Mathur, P. (Prashant), Nordestgaard, B.G. (Børge), Zhao, D. (Dong), Aadahl, M. (Mette), Abarca-Gómez, L. (Leandra), Rahim, H.A. (Hanan Abdul), Abu-Rmeileh, N.M. (Niveen M.), Acosta-Cazares, B. (Benjamin), Adams, R.J. (Robert J.), Agdeppa, I.A. (Imelda A.), Aghazadeh-Attari, J. (Javad), Aguilar-Salinas, C.A. (Carlos A.), Agyemang, C.O. (Charles), Ahluwalia, T.S. (Tarunveer Singh), Ahmad, N.A. (Noor Ani), Ahmadi, A. (Ali), Ahmadi, N. (Naser), Ahmed, S.H. (Soheir H.), Ahrens, W. (W.), Ajlouni, K. (Kamel), Alarouj, M. (Monira), AlBuhairan, F. (Fadia), AlDhukair, S. (Shahla), Ali, M.M. (Mohamed M.), Alkandari, A. (Abdullah), Alkerwi, A. (Ala’a), Aly, E. (Eman), Amarapurkar, D.N. (Deepak N.), Amouyel, P. (Philippe), Andersen, L.B. (Lars Bo), Anderssen, S.A. (Sigmund A.), Anjana, R.M. (Ranjit Mohan), Ansari-Moghaddam, A. (Alireza), Aounallah-Skhiri, H. (Hajer), Araújo, J. (Joana), Ariansen, I. (Inger), Aris, T. (Tahir), Arku, R.E. (Raphael E.), Arlappa, N. (Nimmathota), Aryal, K.K. (Krishna K.), Aspelund, T. (Thor), Assunção, M.C.F. (Maria Cecília F.), Auvinen, J. (Juha), Avdicová, M. (Mária), Azevedo, A. (Ana), Azizi, J. (Joshan), Azmin, M. (Mehrdad), Balakrishna, N. (Nagalla), Bamoshmoosh, M. (Mohamed), Banach, M. (Maciej), Bandosz, P. (Piotr), Banegas, J.R. (José R.), Barbagallo, C.M. (Carlo M.), Barceló, A. (Alberto), Barkat, A. (Amina), Bata, I. (Iqbal), Batieha, A.M. (Anwar M.), Batyrbek, A. (Assembekov), Baur, L.A. (Louise A.), Beaglehole, R. (Robert), Belavendra, A. (Antonisamy), Ben Romdhane, H. (Habiba), Benet, M. (Mikhail), Benn, M. (Marianne), Berkinbayev, S. (Salim), Bernabe-Ortiz, A. (Antonio), Bernotiene, G. (Gailute), Bettiol, H. (Heloisa), Bhargava, S.K. (Santosh K.), Bi, Y. (Yufang), Bienek, A. (Asako), Bikbov, M. (Mukharram), Bista, B. (Bihungum), Bjerregaard, P. (Peter), Bjertness, E. (Espen), Bjertness, M.B. (Marius B.), Björkelund, C. (Cecilia), Bloch, K.V. (Katia V.), Blokstra, A. (Anneke), Bo, S. (Simona), Boehm, B.O. (Bernhard O.), Boggia, J.G. (Jose G.), Boissonnet, C.P. (Carlos P.), Bonaccio, M. (Marialaura), Bongard, V. (Vanina), Borchini, R. (Rossana), Borghs, H. (Herman), Bovet, P. (Pascal), Brajkovich, I. (Imperia), Breckenkamp, J. (Juergen), Brenner, H. (Hermann), Brewster, L.M. (Lizzy), Bruno, G. (Graziella), Bugge, A. (Anna), Busch, M.A. (Markus A.), de León, A.C. (Antonio Cabrera), Cacciottolo, J. (Joseph), Can, G. (Günay), Cândido, A.P.C. (Ana Paula C.), Capanzana, M.V. (Mario V.), Capuano, E. (Eduardo), Capuano, V. (Vincenzo), Cardoso, V.C. (Viviane C.), Carvalho, J. (Joana), Casanueva, F.F., Censi, L. (Laura), Chadjigeorgiou, C.A. (Charalambos A.), Chamukuttan, S. (Snehalatha), Chaturvedi, N. (Nish), Chen, C.-J. (Chien-Jen), Chen, F. (Fangfang), Chen, S. (Shuohua), Cheng, C.-Y. (Ching-Yu), Cheraghian, B. (Bahman), Chetrit, A. (Angela), Chiou, S.-T. (Shu-Ti), Chirlaque, M.D. (M.), Cho, B. (Belong), Cho, Y. (Yumi), Chudek, J. (Jerzy), Claessens, F. (Frank), Clarke, J. (Janine), Clays, E. (Els), Concin, H. (Hans), Confortin, S.C. (Susana C.), Cooper, C. (Charles), Costanzo, S. (Simona), Cottel, D. (Dominique), Cowell, C. (Chris), Crujeiras, A.B. (Ana B.), Csilla, S. (Semánová), Cui, L. (Liufu), Cureau, F.V. (Felipe V.), D’Arrigo, G. (Graziella), d’Orsi, E. (Eleonora), Dallongeville, J., Damasceno, A. (Albertino), Dankner, R. (Rachel), Dantoft, T.M. (Thomas M.), Dauchet, L. (Luc), Davletov, K. (Kairat), Backer, G. (Guy) de, Bacquer, D. (Dirk) de, de Gaetano, G. (Giovanni), De Henauw, S. (Stefaan), de Oliveira, P.D. (Paula Duarte), De Ridder, D. (David), De Smedt, D. (Delphine), Deepa, M. (Mohan), Deev, A.D. (Alexander D.), Dehghan, A. (Abbas), Delisle, H. (Hélène), Dennison, E.M. (Elaine), Deschamps, V. (Valérie), Dhimal, M. (Meghnath), Di Castelnuovo, A.F. (Augusto F.), Dika, Z. (Zivka), Djalalinia, S. (Shirin), Dobson, A.J. (Annette J.), Donfrancesco, C. (Chiara), Donoso, S.P. (Silvana P.), Döring, A. (Angela), Dorobantu, M. (Maria), Dragano, N. (Nico), Drygas, W. (Wojciech), Du, Y. (Yong), Duante, C.A. (Charmaine A.), Duda, R.B. (Rosemary B.), Dzerve, V. (Vilnis), Dziankowska-Zaborszczyk, E. (Elzbieta), Eddie, R. (Ricky), Eftekhar, E. (Ebrahim), Eggertsen, R. (Robert), Eghtesad, S. (Sareh), Eiben, G. (Gabriele), Ekelund, U. (Ulf), El Ati, J. (Jalila), Eldemire-Shearer, D. (Denise), Eliasen, M. (Marie), Elosua, R. (Roberto), Erasmus, R.T. (Rajiv T.), Erbel, R. (Raimund), Erem, C. (Cihangir), Eriksen, L. (Louise), Hagen, K. (Knut), Escobedo-de la Peña, J. (Jorge), Eslami, S. (Saeid), Esmaeili, A. (Ali), Evans, A. (Alun), Faeh, D. (David), Fall, C.H. (Caroline H.), Faramarzi, E. (Elnaz), Farjam, M. (Mojtaba), Fattahi, M.R. (Mohammad Reza), Felix-Redondo, F.J. (Francisco J.), Ferguson, T.S. (Trevor S.), Fernández-Bergés, D. (Daniel), Ferrante, D. (Daniel), Ferrari, M. (Marika), Ferreccio, C. (Catterina), Ferrieres, J. (Jean), Föger, B. (Bernhard), Foo, L.H. (Leng Huat), Forslund, A.-S. (Ann-Sofie), Forsner, M. (Maria), Fouad, H.M. (Heba M.), Francis, D.K. (Damian K.), do Carmo Franco, M. (Maria), Franco, O.H. (Oscar H.), Frontera, G. (Guillermo), Fujita, Y. (Yuki), Fumihiko, M. (Matsuda), Furusawa, T. (Takuro), Gaciong, Z. (Zbigniew), Galvano, F. (Fabio), Gao, J. (Jingli), Garcia-de-la-Hera, M. (Manoli), Garnett, S.P. (Sarah P.), Gaspoz, J.-M. (Jean-Michel), Gasull, M. (Magda), Gazzinelli, A. (Andrea), Geleijnse, J.M. (Marianne), Ghanbari, A. (Ali), Ghasemi, E. (Erfan), Gheorghe-Fronea, O.-F. (Oana-Florentina), Ghimire, A. (Anup), Gianfagna, F. (Francesco), Gill, T.K. (Tiffany K.), Giovannelli, J. (Jonathan), Gironella, G. (Glen), Giwercman, A. (Aleksander), Goltzman, D. (David), Gonçalves, H. (Helen), Gonzalez-Chica, D.A. (David A.), Gonzalez-Gross, M. (Marcela), González-Rivas, J.P. (Juan P.), González-Villalpando, C. (Clicerio), González-Villalpando, M.E. (María Elena), Gonzalez, A.R. (Angel R.), Gottrand, F., Graff-Iversen, S. (Sidsel), Grafnetter, D. (Dušan), Gregor, R.D. (Ronald D.), Grodzicki, T. (Tomasz), Grøntved, A. (Anders), Grosso, G. (Giuseppe), Gruden, G. (Gabriella), Gu, D. (Dongfeng), Guallar-castillón, P. (Pilar), Guan, O.P. (Ong Peng), Gudmundsson, E.F. (Elias F.), Gudnason, V. (Vilmundur), Guerrero, R. (Ramiro), Guessous, I. (Idris), Gunnlaugsdottir, J. (Johanna), Gupta, R. (Rajeev), Gutierrez, L. (Laura), Gutzwiller, F. (Felix), Ha, S. (Seongjun), Hadaegh, F. (Farzad), Haghshenas, R. (Rosa), Hakimi, H. (Hamid), Hambleton, I.R. (Ian R.), Hamzeh, B. (Behrooz), Hantunen, S. (Sari), Kumar, R.H. (Rachakulla Hari), Hashemi-Shahri, S.M. (Seyed Mohammad), Hata, J. (Jun), Haugsgjerd, T. (Teresa), Hayes, A.J. (Alison J.), He, J. (Jiang), He, Y. (Yong), Hendriks, M.E. (Marleen), Henriques, A. (Ana), Herrala, S. (Sauli), Heshmat, R. (Ramin), Hill, A.G. (Allan G.), Ho, S.Y. (Sai Yin), Ho, S.C. (Suzanne C.), Hobbs, M. (Michael), Hofman, A. (Albert), Homayounfar, R. (Reza), Hopman, W.M. (Wilma M.), Horimoto, A.R.V.R. (Andrea R. V. R.), Hormiga, C.M. (Claudia M.), Horta, B.L. (Bernardo L.), Houti, L. (Leila), Howitt, C. (Christina), Htay, T.T. (Thein Thein), Htet, A.S. (Aung Soe), Htike, M.M.T. (Maung Maung Than), Huerta, J.M. (José María), Huhtaniemi, I.T. (I.), Huisman, M. (Martijn), Hunsberger, M.L. (Monica L.), Husseini, A. (Abdullatif), Huybrechts, I. (Inge), Hwalla, N. (Nahla), Iacoviello, L. (Licia), Iannone, A.G. (Anna G.), Ibrahim, M.M. (Mohsen), Wong, N.I. (Norazizah Ibrahim), Iglesia, I. (Iris), Ikeda, N. (Nayu), Ikram, M.A. (Arfan), Iotova, V. (Violeta), Irazola, V.E. (Vilma E.), Ishida, T. (Takafumi), Islam, M. (Muhammad), al-Safi Ismail, A. (Aziz), Iwasaki, M. (Masanori), Jacobs, J.M. (Jeremy M.), Jaddou, H.Y. (Hashem Y.), Jafar, T.H. (Tazeen), James, K. (Kenneth), Jamrozik, K., Janszky, I. (Imre), Janus, E. (Edward), Jarvelin, M.-R. (Marjo-Riitta), Jasienska, G. (Grazyna), Jelakovic, A. (Ana), Jelakovic, B. (Bojan), Jennings, G. (Garry), Jensen, G.B. (Gorm), Jeong, S.-L. (Seung-lyeal), Jha, A.K. (Anjani Kumar), Jiang, C.Q. (Chao Qiang), Jimenez, R.O. (Ramon O.), JöCkel, K.-H. (Karl-Heinz), Joffres, M. (Michel), Jokelainen, J.J. (Jari J.), Jonas, J.B. (Jost B.), Jorgensen, T. (Torben), Joshi, P. (Pradeep), Joukar, F. (Farahnaz), Józwiak, J. (Jacek), Juolevi, A. (Anne), Kafatos, A. (Anthony), Kajantie, E. (Eero), Kalter-Leibovici, O. (Ofra), Kamaruddin, N.A. (Nor Azmi), Kamstrup, P.R. (Pia R.), Karki, K.B. (Khem B.), Katz, J. (Joanne), Kauhanen, J. (Jussi), Kaur, P. (Prabhdeep), Kavousi, M. (Maryam), Kazakbaeva, G. (Gyulli), Keil, M. (Mark), Keinanen-Kiukaanniemi, S. (Sirkka), Kelishadi, R. (Roya), Keramati, M. (Maryam), Kerimkulova, A. (Alina), Kersting, M. (Mathilde), Khader, Y.S. (Yousef Saleh), Khalili, D. (Davood), Khateeb, M. (Mohammad), Kheradmand, M. (Motahareh), Khosravi, A. (Alireza), Kiechl-Kohlendorfer, U. (Ursula), Kiechl, S. (Stefan), Killewo, J. (Japhet), Kim, H.C. (Hyeon Chang), Kim, J. (Jeongseon), Kim, Y.-Y. (Yeon-Yong), Klumbiene, J. (Jurate), Knoflach, M. (Michael), Ko, S. (Stephanie), Kohler, H.-P. (Hans-Peter), Kohler, I.V. (Iliana V.), Kolle, E. (Elin), Kolsteren, P. (Patrick), König, J. (Jürgen), Korpelainen, R. (Raija), Korrovits, P. (Paul), Kos, J. (Jelena), Koskinen, S. (Seppo), Kouda, K. (Katsuyasu), Kowlessur, S. (Sudhir), Kratzer, W. (Wolfgang), Kriemler, S. (Susi), Kristensen, P.L. (Peter Lund), Krokstad, S. (Steiner), Kromhout, D. (Daan), Kujala, U.M. (Urho), Kurjata, P. (Pawel), Kyobutungi, C. (Catherine), Laamiri, F.Z. (Fatima Zahra), Laatikainen, T. (Tiina), Lachat, C. (Carl), Laid, Y. (Youcef), Lam, T.H. (Tai Hing), Lambrinou, C.-P. (Christina-Paulina), Lanska, V. (Vera), Lappas, G. (Georg), Larijani, B. (Bagher), Latt, T.S. (Tint Swe), Laugsand, L.E. (Lars E.), Lazo-Porras, M. (Maria), Lee, J. (Jeannette), Lee, J. (Jeonghee), Lehmann, N. (Nils), Lehtimäki, T. (Terho), Levitt, N.S. (Naomi S.), Li, Y. (Yanping), Lilly, C.L. (Christa L.), Lim, W.-Y. (Wei-Yen), Lima-Costa, M.F. (Maria Fernanda), Lin, H.-H. (Hsien-Ho), Lin, X. (Xu), Lin, Y.-T. (Yi-Ting), Kao, W.H.L. (Wen), Linneberg, A. (Allan), Lissner, L. (Lauren), Liu, J. (Jing), Loit, H.-M. (Helle-Mai), Lopez-Garcia, E. (Esther), Lopez, T. (Tania), Lotufo, P.A. (Paulo A), Lozano, J.E. (José Eugenio), Luksiene, D. (Dalia), Lundqvist, A. (Annamari), Lundqvist, R. (Robert), Lunet, N. (Nuno), Ma, G. (Guansheng), Machado-Coelho, G.L.L. (George L. L.), Machado-Rodrigues, A.M. (Aristides M.), Machi, S. (Suka), Madar, A.A. (Ahmed A.), Maggi, S. (Stefania), Magliano, D.J., Magriplis, E. (Emmanuella), Mahasampath, G. (Gowri), Maire, B. (Bernard), Makdisse, M. (Marcia), Malekzadeh, F. (Fatemeh), Malekzadeh, R. (Reza), Rao, K.M. (Kodavanti Mallikharjuna), Manios, Y., Mann, J.I. (Jim I.), Mansour-Ghanaei, F. (Fariborz), Manzato, E. (Enzo), Marques-Vidal, P. (Pedro), Martorell, R. (Reynaldo), Mascarenhas, L.P. (Luis P.), Mathiesen, E.B. (Ellisiv), Matsha, T.E. (Tandi E.), Mavrogianni, C. (Christina), McFarlane, S.R. (Shelly R.), McGarvey, S.T. (Stephen T.), McLachlan, S. (Stela), McLean, R.M. (Rachael M.), McLean, S.B. (Scott B.), McNulty, B.A. (Breige A.), Mediene-Benchekor, S. (Sounnia), Mehdipour, P. (Parinaz), Mehlig, K. (Kirsten), Mehrparvar, A.H. (Amir Houshang), Meirhaeghe, A. (Aline), Meisinger, C. (Christa), Menezes, A.M.B. (Ana M.B.), Menon, G.R. (Geetha R.), Merat, S. (Shahin), Mereke, A. (Alibek), Meshram, I.I. (Indrapal I.), Metcalf, P. (Patricia), Meyer, H.E. (Haakon E.), Mi, J. (Jie), Michels, N. (Nathalie), Miller, J.C. (Jody C.), Minderico, C.S. (Cláudia S.), Mini, G.K. (G. K.), Miquel, J.F. (Juan Francisco), Miranda, J.J. (J. Jaime), Mirjalili, M.R. (Mohammad Reza), Mirrakhimov, E. (Erkin), Modesti, P.A. (Pietro A.), Moghaddam, S.S. (Sahar Saeedi), Mohajer, B. (Bahram), Mohamed, M.K. (Mostafa K.), Mohammad, K. (Kazem), Mohammadi, Z. (Zahra), Mohammadifard, N. (Noushin), Mohammadpourhodki, R. (Reza), Mohan, V. (Viswanathan), Mohanna, S. (Salim), Yusoff, M.F.M. (Muhammad Fadhli Mohd), Mohebbi, I. (Iraj), Mohebi, F. (Farnam), Moitry, M. (Marie), Møllehave, L.T. (Line T.), Møller, N.C. (Niels C.), Molnár, D. (Dénes), Momenan, A. (Amirabbas), Mondo, C.K. (Charles K.), Monterrubio-Flores, E. (Eric), Moosazadeh, M. (Mahmood), Morejon, A. (Alain), Moreno, L. (Luis), Morgan, K. (Karen), Morin, S.N. (Suzanne N.), Moschonis, G. (George), Mossakowska, M. (Malgorzata), Mostafa, A. (Aya), Mota, J. (Jorge), Motlagh, M.E. (Mohammad Esmaeel), Motta, J. (Jorge), Msyamboza, K.P. (Kelias P.), Muiesan, M.L. (Maria Lorenza), Müller-Nurasyid, M. (Martina), Mursu, J. (Jaakko), Mustafa, N. (Norlaila), Nabipour, I. (Iraj), Naderimagham, S. (Shohreh), Nagel, G. (Gabriele), Naidu, B.M. (Balkish M.), Najafi, F. (Farid), Nakamura, H. (Harunobu), Námešná, J. (Jana), Nang, E.E.K. (Ei Ei K.), Nangia, V.B. (Vinay B.), Nauck, M. (Matthias), Neal, W.A. (William A.), Nejatizadeh, A. (Azim), Nenko, I. (Ilona), Nervi, F. (Flavio), Nguyen, N.D. (Nguyen D.), Nguyen, Q.N. (Quang Ngoc), Nieto-Martínez, R.E. (Ramfis E.), Nihal, T. (Thomas), Niiranen, T.J. (Teemu J.), Ning, G. (Guang), Ninomiya, T. (Toshiharu), Noale, M. (Marianna), Noboa, O.A. (Oscar A.), Noto, D. (Davide), Nsour, M.A. (Mohannad Al), Nuhoğlu, I. (Irfan), O’Neill, T.W. (Terence W.), O’Reilly, D. (Dermot), Ochoa-Avilés, A.M. (Angélica M.), Oh, K. (Kyungwon), Ohtsuka, R. (Ryutaro), Olafsson, Ö. (Örn), Olié, V. (Valérie), Oliveira, I.O. (Isabel O.), Omar, M.A. (Mohd Azahadi), Onat, A. (Altan), Ong, S.K. (Sok King), Ordunez, P. (Pedro), Ornelas, R. (Rui), Ortiz, P.J. (Pedro J.), Osmond, C. (Clive), Ostojic, S.M. (Sergej M.), Ostovar, A. (Afshin), Otero, J.A. (Johanna A.), Owusu-Dabo, E. (Ellis), Paccaud, F.M. (Fred Michel), Pahomova, E. (Elena), Pajak, A. (Andrzej), Palmieri, L. (Luigi), Pan, W.-H. (Wen-Harn), Panda-Jonas, S. (Songhomitra), Panza, F. (Francesco), Parnell, W.R. (Winsome R.), Patel, N.D. (Nikhil D.), Peer, N. (Nasheeta), Peixoto, S.V. (Sergio Viana), Peltonen, M. (Markku), Pereira, A. (A.), Peters, A. (Annette), Petersmann, A. (Astrid), Petkeviciene, J. (Janina), Peykari, N. (Niloofar), Pham, S.T. (Son Thai), Pichardo, R.N. (Rafael N.), Pigeot, I. (Iris), Pilav, A. (Aida), Pilotto, A. (Alberto), Piwonska, A. (Aleksandra), Pizarro, A.N. (Andreia N.), Plans-Rubió, P. (Pedro), Plata, S. (Silvia), Pohlabeln, H. (Hermann), Porta, M. (Miquel), Portegies, M.L.P. (Marileen), Poudyal, A. (Anil), Pourfarzi, F. (Farhad), Poustchi, H. (Hossein), Pradeepa, R. (Rajendra), Price, J.F. (Jacqueline F.), Providencia, R. (Rui), Puder, J.J. (Jardena J.), Puhakka, S.E. (Soile E.), Punab, M. (Margus), Qorbani, M. (Mostafa), Bao, T.Q. (Tran Quoc), Radisauskas, R. (Ricardas), Rahimikazerooni, S. (Salar), Raitakari, O. (Olli), Rao, S.R. (Sudha Ramachandra), Ramachandran, A. (Ambady), Ramos, E. (Elisabete), Ramos, R. (Rafel), Rampal, L. (Lekhraj), Rampal, S. (Sanjay), Redón, J. (Josep), Reganit, P.F.M. (Paul Ferdinand M.), Revilla, L. (Luis), Rezaianzadeh, A. (Abbas), Ribeiro, R. (Robespierre), Richter, A. (Adrian), Rigo, F. (Fernando), Rinke de Wit, T.F. (Tobias), Rodríguez Artalejo, F. (Fernando), del Cristo Rodriguez-Perez, M. (María), Rodríguez-Villamizar, L.A. (Laura A.), Roggenbuck, U. (Ulla), Rojas-Martinez, R. (Rosalba), Romaguera, D. (Dora), Romeo, E.L. (Elisabetta L.), Rosengren, A. (Annika), Roy, J.G.R. (Joel G. R.), Rubinstein, A. (Adolfo), Ruidavets, J.-B. (Jean-Bernard), Ruiz-Betancourt, B.S. (Blanca Sandra), Russo, P. (Paola), Rust, P. (Petra), Rutkowski, M. (Marcin), Sabanayagam, C. (Charumathi), Sachdev, H.S. (Harshpal S.), Sadjadi, A. (Alireza), Safarpour, A.R. (Ali Reza), Safiri, S. (Saeid), Saidi, O. (Olfa), Saki, N. (Nader), Salanave, B. (Benoit), Salmerón, D. (Diego), Salomaa, V. (Veikko), Salonen, J.T. (Jukka T.), Salvetti, M. (Massimo), Sánchez-Abanto, J. (Jose), Sans, S. (Susana), Santaliestra-Pasías, A.M. (Alba M.), Santos, D.A. (Diana A.), Santos, M.P. (Maria Paula), Santos, R. (Rute), Saramies, J.L. (Jouko L.), Sardinha, L.B. (Luis B.), Sarrafzadegan, N. (Nizal), Saum, K.-U. (Kai-Uwe), Savva, S., Sawada, N. (Norie), Sbaraini, M. (Mariana), Scazufca, M. (Marcia), Schaan, B.D. (Beatriz D.), Schargrodsky, H. (Herman), Scheidt-Nave, C. (C.), Schienkiewitz, A. (Anja), Schipf, S. (Sabine), Schmidt, C.O. (Carsten O.), Schöttker, B. (Ben), Schramm, S. (Sara), Sebert, S. (Sylvain), Sein, A.A. (Aye Aye), Sen, A. (Abhijit), Sepanlou, S.G. (Sadaf G), Servais, J. (Jennifer), Shakeri, R. (Ramin), Shalnova, S.A. (Svetlana A.), Shamah-Levy, T. (Teresa), Sharafkhah, M. (Maryam), Sharma, S.K. (Sanjib K.), Shaw, J.E., Shayanrad, A. (Amaneh), Shi, Z. (Zumin), Shibuya, K. (Kenji), Shimizu-Furusawa, H. (Hana), Shin, D.W. (Dong Wook), Shin, Y. (Youchan), Shirani, M. (Majid), Shiri, R. (Rahman), Shrestha, N. (Namuna), Si-Ramlee, K. (Khairil), Siani, A. (Alfonso), Siantar, R. (Rosalynn), Sibai, A.M. (Abla M.), Silva, D.A.S. (Diego Augusto Santos), Simon, M. (Mary), Simons, J. (Judith), Simons, L.A. (Leon A.), Sjöström, M. (Michael), Skaaby, T. (Tea), Slowikowska-Hilczer, J. (Jolanta), Slusarczyk, P. (Przemyslaw), Smeeth, L. (Liam), Snijder, M.B. (Marieke), Söderberg, S. (Stefan), Soemantri, A. (Augustinus), Sofat, R. (Reecha), Solfrizzi, V. (Vincenzo), Somi, M.H. (Mohammad Hossein), Sonestedt, E. (Emily), Sørensen, T.I.A. (Thorkild), Jérome, C.S. (Charles Sossa), Soumaré, A. (Aicha), Sozmen, K. (Kaan), Sparrenberger, K. (Karen), Staessen, J.A. (Jan), Stathopoulou, M.G. (Maria G), Stavreski, B. (Bill), Steene-Johannessen, J. (Jostein), Stehle, P. (Peter), Stein, A.D. (Aryeh D.), Stessman, J. (Jochanan), Stevanović, R. (Ranko), Stieber, J. (Jutta), Stöckl, D. (Doris), Stokwiszewski, J. (Jakub), Stronks, K. (Karien), Strufaldi, M.W. (Maria Wany), Suárez-Medina, R. (Ramón), Sun, C.-A. (Chien-An), Sundström, J. (Johan), Suriyawongpaisal, P. (Paibul), Sy, R.G. (Rody G.), Sylva, R.C. (René Charles), Szklo, M. (Moyses), Tai, E.S. (Shyong), Tamosiunas, A. (Abdonas), Tan, E.J. (Eng Joo), Tarawneh, M.R. (Mohammed Rasoul), Tarqui-Mamani, C.B. (Carolina B.), Taylor, A. (Anne), Taylor, J. (Julie), Tell, G.S. (Grethe S.), Tello, T. (Tania), Thankappan, K.R. (K. R.), Thijs, L. (Lutgarde), Thuesen, B.H. (Betina H.), Toft, U. (Ulla), Tolonen, H.K. (Hanna K.), Tolstrup, J.S. (Janne), Topbas, M. (Murat), Topór-Madry, R. (Roman), Tormo, M.J., Tornaritis, M.J. (Michael J.), Torrent, M. (Maties), Torres-Collado, L. (Laura), Traissac, P. (Pierre), Trinh, O.T.H. (Oanh T. H.), Truthmann, J. (Julia), Tsugane, S. (Shoichiro), Tulloch-Reid, M.K. (Marshall K.), Tuomainen, T.-P. (Tomi-Pekka), Tuomilehto, J. (Jaakko), Tybjaerg-Hansen, A. (Anne), Tzourio, C. (Christophe), Ueda, P. (Peter), Ugel, E. (Eunice), Ulmer, H. (Hanno), Unal, B. (Belgin), Uusitalo, H., Valdivia, G. (Gonzalo), Valvi, D. (Damaskini), Dam, R.M. (Rob) van, Schouw, Y.T. (Yvonne) van der, Van Herck, K. (Koen), Van Minh, H. (Hoang), Rossem, L. (Lenie) van, Schoor, N.M. (Natasja) van, Valkengoed, I. (Irene) van, Vanderschueren, D. (Dirk), Vanuzzo, D. (Diego), Varbo, A. (Anette), Varona-Pérez, P. (Patricia), Vasan, S.K. (Senthil K.), Vatten, L. (Lars), Vega, T. (Tomas), Veidebaum, T. (Toomas), Velasquez-Melendez, G. (Gustavo), Venero-Fernández, S.J. (Silvia J.), Veronesi, G. (Giovanni), Verschuren, W.M.M. (W. M. Monique), Victora, C.G. (Cesar G.), Vidiawati, D. (Dhanasari), Viet, L. (Lucie), Villalpando, S. (Salvador), Vioque, J. (Jesus), Virtanen, J.K. (Jyrki K.), Visvikis-Siest, S. (Sophie), Viswanathan, B. (Bharathi), Vlasoff, T. (Tiina), Vollenweider, P. (Peter), Voutilainen, A. (Ari), Wade, A.N. (Alisha N.), Wagner, A. (Aline), Walton, J. (Janette), Bebakar, W.M.W. (Wan Mohamad Wan), Mohamud, W.N.W. (Wan Nazaimoon Wan), Wang, M.-D. (Ming-Dong), Wang, N. (Ningli), Wang, Q. (Qian), Wang, Y.X. (Ya Xing), Wang, Y.-W. (Ying-Wei), Wannamethee, S.G. (Goya), Wedderkopp, N. (Niels), Wei, W. (Wenbin), Whincup, P.H. (Peter), Widhalm, K. (Kurt), Widyahening, I.S. (Indah S.), Wiecek, A. (Andrzej), Wijga, A.H. (Alet), Wilks, R.J. (Rainford J.), Willeit, J. (Johann), Willeit, P. (Peter), Wilsgaard, T. (Tom), Wojtyniak, B. (Bogdan), Wong-McClure, R.A. (Roy A.), Wong, A. (Andrew), Wong, T.Y. (Tien Yin), Woo, J. (Jean), Woodward, M. (Mark), Wu, F.C. (Frederick C.), Wu, S. (Shouling), Xu, H. (Haiquan), Xu, L. (Liang), Yan, W. (Weili), Yang, X. (Xiaoguang), Yasuharu, T. (Tabara), Ye, X. (Xingwang), Yeow, T.P. (Toh Peng), Yiallouros, P.K. (P.), Yoosefi, M. (Moein), Yoshihara, A. (Akihiro), You, S.-L. (San-Lin), Younger-Coleman, N.O. (Novie O.), Yusoff, A.F. (Ahmad Faudzi), Zainuddin, A.A. (Ahmad A.), Zakavi, S.R. (Seyed Rasoul), Zali, M.R. (Mohammad Reza), Zamani, F. (Farhad), Zambon, S. (Sabina), Zampelas, A. (Antonis), Zaw, K.K. (Ko Ko), Zdrojewski, T. (T.), Vrkic, T.Z. (Tajana Zeljkovic), Zhang, Z.-Y. (Zhen-Yu), Zhao, W. (Wenhua), Zhen, S. (Shiqi), Zheng, Y. (Yingfeng), Zholdin, B. (Bekbolat), Zhussupov, B. (Baurzhan), Zoghlami, N. (Nada), Cisneros, J.Z. (Julio Zuñiga), Gregg, E.W. (Edward W.), and Ezzati, M. (Majid)
Abstract: High blood cholesterol is typically considered a feature of wealthy western countries1,2. However, dietary and behavioural determinants of blood cholesterol are changing rapidly throughout the world3 and countries are using lipid-lowering medications at varying rates. These changes can have distinct effects on the levels of high-density lipoprotein (HDL) cholesterol and non-HDL cholesterol, which have different effects on human health4,5. However, the trends of HDL and non-HDL cholesterol levels over time have not been previously reported in a global analysis. Here we pooled 1,127 population-based studies that measured blood lipids in 102.6 million individuals aged 18 years and older to estimate trends from 1980 to 2018 in mean total, non-HDL and HDL cholesterol levels for 200 countries. Globally, there was little change in total or non-HDL cholesterol from 1980 to 2018. This was a net effect of increases in low- and middle-income countries, especially in east and southeast Asia, and decreases in high-income western countries, especially those in northwestern Europe, and in central and eastern Europe. As a result, countries with the highest level of non-HDL cholesterol—which is a marker of cardiov
Published: 2020
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5. Falls in older aged adults in 22 European countries: Incidence, mortality and burden of disease from 1990 to 2017

Author: Haagsma, J.A. (Juanita), Olij, B.F. (Branko), Majdan, M. (Marek), Beeck, E.F. (Ed) van, Vos, T. (Theo), Castle, C.D. (Chris D.), Dingels, Z.V. (Zachary V.), Fox, J.T. (Jack T.), Hamilton, E.B. (Erin B.), Liu, Z. (Zichen), Roberts, N.L.S. (Nicholas L.S.), Sylte, D.O. (Dillon O.), Aremu, O. (Olatunde), Bärnighausen, T. (Till), Borzì, A.M. (Antonio M.), Briggs, A.M. (Andrew M.), Carrero, J.J. (Juan J.), Cooper, C. (Charles), El-Khatib, Z. (Ziad), Ellingsen, C.L. (Christian Lycke), Fereshtehnejad, S.-M. (Seyed-Mohammad), Filip, I. (Irina), Fischer, F. (Florian), Haro, J.M. (Josep Maria), Jonas, J.B. (Jost B.), Kiadaliri, A.A. (Aliasghar A.), Koyanagi, A. (Ai), Lunevicius, R. (Raimundas), Meretoja, T.J. (Tuomo J.), Mohammed, S. (Shafiu), Pathak, A. (Ashish), Radfar, A. (Amir), Rawaf, S. (Salman), Rawaf, D.L. (David Laith), Riera, L.S. (Lidia Sanchez), Shiue, I. (Ivy), Vasankari, T.J. (Tommi Juhani), James, S.L. (Spencer L.), Polinder, S. (Suzanne), Haagsma, J.A. (Juanita), Olij, B.F. (Branko), Majdan, M. (Marek), Beeck, E.F. (Ed) van, Vos, T. (Theo), Castle, C.D. (Chris D.), Dingels, Z.V. (Zachary V.), Fox, J.T. (Jack T.), Hamilton, E.B. (Erin B.), Liu, Z. (Zichen), Roberts, N.L.S. (Nicholas L.S.), Sylte, D.O. (Dillon O.), Aremu, O. (Olatunde), Bärnighausen, T. (Till), Borzì, A.M. (Antonio M.), Briggs, A.M. (Andrew M.), Carrero, J.J. (Juan J.), Cooper, C. (Charles), El-Khatib, Z. (Ziad), Ellingsen, C.L. (Christian Lycke), Fereshtehnejad, S.-M. (Seyed-Mohammad), Filip, I. (Irina), Fischer, F. (Florian), Haro, J.M. (Josep Maria), Jonas, J.B. (Jost B.), Kiadaliri, A.A. (Aliasghar A.), Koyanagi, A. (Ai), Lunevicius, R. (Raimundas), Meretoja, T.J. (Tuomo J.), Mohammed, S. (Shafiu), Pathak, A. (Ashish), Radfar, A. (Amir), Rawaf, S. (Salman), Rawaf, D.L. (David Laith), Riera, L.S. (Lidia Sanchez), Shiue, I. (Ivy), Vasankari, T.J. (Tommi Juhani), James, S.L. (Spencer L.), and Polinder, S. (Suzanne)
Abstract: Introduction: Falls in older aged adults are an important public health problem. Insight into differences in fall-related injury rates between countries can serve as important input for identifying and evaluating prevention strategies. The objectives of this study were to compare Global Burden of Disease (GBD) 2017 estimates on incidence, mortality and disability-adjusted life years (DALYs) due to fall-related injury in older adults across 22 countries in the Western European region and to examine changes over a 28-year period. Methods: We performed a secondary database descriptive study using the GBD 2017 results on age-standardised fall-related injury in older adults aged 70 years and older in 22 countries from 1990 to 2017. Results: In 2017, in the Western European region, 13 840 per 100 000 (uncertainty interval (UI) 11 837-16 113) older adults sought medical treatment for fall-related injury, ranging from 7594 per 100 000 (UI 6326-9032) in Greece to 19 796 per 100 000 (UI 15 536-24 233) in Norway. Since 1990, fall-related injury DALY rates showed little change for the whole region, but patterns varied widely between countries. Some countries (eg, Belgium and Netherlands) have lost their favourable positions due to an increasing fall-related injury burden of disease since 1990. Conclusions: From 1990 to 2017, there was considerable variation in fall-related injury incidence, mortality, DALY rates and its composites in the 22 countries in the Western European region. It may be useful to assess which fall prevention measures have been taken in countries that showed continuous low or decreasing incidence, death and DALY rates despite ageing of the population.
Published: 2020
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6. Deriving the dietary approaches to stop hypertension (DASH) score in women from seven pregnancy cohorts from the European alphabet consortium

Author: Aubert, A.M. (Adrien M.), Forhan, A. (Anne), de Lauzon-Guillain, B. (Blandine), Chen, L.W. (Ling Wei), Polanska, K. (Kinga), Hanke, W. (Wojciech), Jankowska, A. (Agnieszka), Mensink-Bout, S.M. (Sara M.), Duijts, L. (Liesbeth), Suderman, M.J. (Matthew J.), Relton, C.L. (Caroline), Crozier, S.R. (Sarah R.), Harvey, N.C. (Nicholas), Cooper, C. (Charles), McAuliffe, F.M. (Fionnuala M.), Kelleher, J.F. (Joseph), Phillips, C.M. (Catherine M.), Heude, B. (Barbara), Bernard, J.Y. (Jonathan Y.), Aubert, A.M. (Adrien M.), Forhan, A. (Anne), de Lauzon-Guillain, B. (Blandine), Chen, L.W. (Ling Wei), Polanska, K. (Kinga), Hanke, W. (Wojciech), Jankowska, A. (Agnieszka), Mensink-Bout, S.M. (Sara M.), Duijts, L. (Liesbeth), Suderman, M.J. (Matthew J.), Relton, C.L. (Caroline), Crozier, S.R. (Sarah R.), Harvey, N.C. (Nicholas), Cooper, C. (Charles), McAuliffe, F.M. (Fionnuala M.), Kelleher, J.F. (Joseph), Phillips, C.M. (Catherine M.), Heude, B. (Barbara), and Bernard, J.Y. (Jonathan Y.)
Abstract: The ALPHABET consortium aims to examine the interplays between maternal diet quality, epigenetics and offspring health in seven pregnancy/birth cohorts from five European countries. We aimed to use the Dietary Approaches to Stop Hypertension (DASH) score to assess diet quality, but different versions have been published. To derive a single DASH score allowing cross-country, cross-cohort and cross-period comparison and limiting data heterogeneity within the ALPHABET consortium, we harmonised food frequency questionnaire (FFQ) data collected before and during pregnancy in ≥26,500 women. Although FFQs differed strongly in length and content, we derived a consortium DASH score composed of eight food components by combining the prescriptive original DASH and the DASH described by Fung et al. Statistical issues tied to the nature of the FFQs led us to re-classify two food groups (grains and dairy products). Most DASH food components exhibited pronounced between-cohort variability, including non-full-fat dairy products (median intake ranging from 0.1 to 2.2 servings/day), sugar-sweetened beverages/sweets/added sugars (0.3–1.7 servings/day), fruits (1.1–3.1 servings/day), and vegetables (1.5–3.6 servings/day). We successfully developed a harmonized DASH score adapted to all cohorts being part of the ALPHABET consortium. This methodological work may benefit other research teams in adapting the DASH to their study’s specificities.
Published: 2019
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7. The global burden of falls: Global, regional and national estimates of morbidity and mortality from the Global Burden of Disease Study 2017

Author: James, S.L. (Spencer L.), Lucchesi, L.R. (Lydia R.), Bisignano, C. (Catherine), Castle, C.D. (Chris D.), Dingels, Z.V. (Zachary V.), Fox, J.T. (Jack T), Hamilton, E.B. (Erin B.), Henry, N.J. (Nathaniel J.), Krohn, K.J. (Kris J.), Liu, Z. (Zichen), Mccracken, D. (Darrah), Nixon, M.R. (Molly R.), Roberts, N.L.S. (Nicholas L. S.), Sylte, D.O. (Dillon O.), Adsuar, J.C. (José C), Arora, A. (Amit), Briggs, A.M. (Andrew M.), Collado-Mateo, D. (Daniel), Cooper, C. (Charles), Dandona, L. (Lalit), Dandona, R. (Rakhi), Ellingsen, C.L. (Christian Lycke), Fereshtehnejad, S.-M. (Seyed-Mohammad), Gill, T.K. (Tiffany K.), Haagsma, J.A. (Juanita), Hendrie, D. (Delia), Jürisson, M. (Mikk), Kumar, G.A. (G Anil), Lopez, A.D. (Alan D), Miazgowski, T. (T.), Miller, T.R. (Ted R), Mini, G.K. (G. K.), Mirrakhimov, E.M. (Erkin M.), Mohamadi, E. (Efat), Olivares, P.R. (Pedro), Rahim, F. (Fakher), Riera, L.S. (Lidia Sanchez), Villafaina, S. (Santos), Yano, Y. (Yuichiro), Hay, S.I. (Simon), Lim, S.S. (Stephen), Mokdad, A.H. (Ali H.), Naghavi, M. (Morteza), Murray, C.J.L. (Christopher), James, S.L. (Spencer L.), Lucchesi, L.R. (Lydia R.), Bisignano, C. (Catherine), Castle, C.D. (Chris D.), Dingels, Z.V. (Zachary V.), Fox, J.T. (Jack T), Hamilton, E.B. (Erin B.), Henry, N.J. (Nathaniel J.), Krohn, K.J. (Kris J.), Liu, Z. (Zichen), Mccracken, D. (Darrah), Nixon, M.R. (Molly R.), Roberts, N.L.S. (Nicholas L. S.), Sylte, D.O. (Dillon O.), Adsuar, J.C. (José C), Arora, A. (Amit), Briggs, A.M. (Andrew M.), Collado-Mateo, D. (Daniel), Cooper, C. (Charles), Dandona, L. (Lalit), Dandona, R. (Rakhi), Ellingsen, C.L. (Christian Lycke), Fereshtehnejad, S.-M. (Seyed-Mohammad), Gill, T.K. (Tiffany K.), Haagsma, J.A. (Juanita), Hendrie, D. (Delia), Jürisson, M. (Mikk), Kumar, G.A. (G Anil), Lopez, A.D. (Alan D), Miazgowski, T. (T.), Miller, T.R. (Ted R), Mini, G.K. (G. K.), Mirrakhimov, E.M. (Erkin M.), Mohamadi, E. (Efat), Olivares, P.R. (Pedro), Rahim, F. (Fakher), Riera, L.S. (Lidia Sanchez), Villafaina, S. (Santos), Yano, Y. (Yuichiro), Hay, S.I. (Simon), Lim, S.S. (Stephen), Mokdad, A.H. (Ali H.), Naghavi, M. (Morteza), and Murray, C.J.L. (Christopher)
Abstract: Background: Falls can lead to severe health loss including death. Past research has shown that falls are an important cause of death and disability worldwide. The Global Burden of Disease Study 2017 (GBD 2017) provides a comprehensive assessment of morbidity and mortality from falls. Methods: Estimates for mortality, years of life lost (YLLs), incidence, prevalence, years lived with disability (YLDs) and disability-adjusted life years (DALYs) were produced for 195 countries and territories from 1990 to 2017 for all
Published: 2019
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8. Diagnosis and Management of Paget's Disease of Bone in Adults: A Clinical Guideline

Author: Ralston, S.H. (Stuart), Corral-Gudino, L., Cooper, C. (Charles), Francis, R.M., Fraser, W.D. (William), Gennari, L., Guanabens, N., Javaid, M.K., Layfield, R., O'Neill, T.W. (Terence), Russell, R.G.G., Stone, M.D., Simpson, K, Wilkinson, D., Wills, R., Zillikens, M.C. (Carola), Tuck, S.P., Ralston, S.H. (Stuart), Corral-Gudino, L., Cooper, C. (Charles), Francis, R.M., Fraser, W.D. (William), Gennari, L., Guanabens, N., Javaid, M.K., Layfield, R., O'Neill, T.W. (Terence), Russell, R.G.G., Stone, M.D., Simpson, K, Wilkinson, D., Wills, R., Zillikens, M.C. (Carola), and Tuck, S.P.
Abstract: An evidence-based clinical guideline for the diagnosis and management of Paget’s disease of bone (PDB) was developed using GRADE methodology, by a Guideline Development Group (GDG) led by the Paget’s Association (UK). A systematic review of diagnostic tests and pharmacological and nonpharmacological treatment options was conducted that sought to address several key questions of clinical relevance. Twelve recommendations and five conditional recommendations were made, but there was insufficient evidence to address eight of the questions posed. The following recommendations were identified as the most important: 1) Radionuclide bone scans, in addition to targeted radiographs, are recommended as a means of fully and accurately defining the extent of metabolically active disease in patients with PDB. 2) Serum total alkaline phosphatase (ALP) is recommended as a first-line biochemical screening test in combination with liver function tests in screening for the presence of metabolically active PDB. 3) Bisphosphonates are recommended for the treatment of bone pain associated with PDB. Zoledronic acid is recommended as the bisphosphonate most likely to give a favorable pain response. 4) Treatment aimed at improving symptoms is recommended over a treat-to-target strategy aimed at normalizing total ALP in PDB. 5) Total hip or knee replacements are recommended for patients with PDB who develop osteoarthritis in whom medical treatment is inadequate. There is insufficient information to recommend one type of surgical approach over another. The guideline was endorsed by the European Calcified Tissues Society, the International Osteoporosis Foundation, the American Society of Bone and Mineral Research, the Bone Research Society (UK), and the British Geriatric Society. The GDG noted that there had been a lack of research on patient-focused clinical outcomes in PDB and identified several areas where further research was needed. © 2019 The Authors. Journal of Bone and Mineral Researc
Published: 2019
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9. Evidence for three genetic loci involved in both anorexia nervosa risk and variation of body mass index

Author: Hinney, A. (Anke), Kesselmeier, M. (M.), Jall, S. (S.), Volckmar, A.-L. (A. L.), Föcker, M. (M.), Antel, J. (J.), Heid, I.M. (Iris), Winkler, T.W. (Thomas W.), Grant, S.F.A. (S. F.A.), Guo, Y. (Yongli), Bergen, A.W. (Andrew), Grant, S.F.A. (Struan), Berrettini, W. (Wade), Hakonarson, H. (Hakon), Herpertz-Dahlmann, B. (B.), De Zwaan, M. (M.), Herzog, W. (W.), Ehrlich, S.M. (Stefan), Zipfel, S. (S.), Egberts, K. (Karin), Adan, R. (R.), Brandys, M. (M.), Elburg, A.A. (Annemarie) van, Boraska Perica, V. (V.), Müller, T.D., Tschöp, M.H. (M. H.), Zeggini, E. (Eleftheria), Bulik, C.M. (C. M.), Collier, D.A. (David), Scherag, A. (A.), Hebebrand, J. (J.), Tschop, M. (Matthias), Floyd, J. (Jamie), Thornton, L.M. (Laura), Huckins, L.M. (Laura M), Southam, L. (Lorraine), Rayner, N.W. (Nigel William), Tachmazidou, I. (Ioanna), Klump, K.L. (K. L.), Treasure, J. (Janet), Lewis, C.M. (Cathryn), Schmidt, U. (Ulrike), Tozzi, F. (Federica), Iezebrink, K. (Kirsty), Gorwood, P. (Philip), Kas, M.J.H. (Martien), Favaro, A. (Angela), Santonastaso, P. (Paolo), Fernández-Aranda, F. (Fernando), Gratacos, M. (Monica), Rybakowski, F. (Filip), Dmitrzak-Weglarz, M. (Monika), Kaprio, J. (Jaakko), Keski-Rahkonen, A. (Anna), Raevuori-Helkamaa, A. (Anu), Furth, E.F. (Eric) van, Slof-Op’t Landt, M.C.T. (Margarita C. T.), Hudson, J.I. (James I), Knudsen, G.P.S. (Gun Peggy S.), Monteleone, P. (Palmiero), Kaplan, A.S. (Allan S), Karwautz, A. (Andreas), Li, D. (Dong), Komaki, G. (Gen), Ando, T. (Tetsuya), Inoko, H. (Hidetoshi), Esko, T. (T.), Fischer, K. (Krista), Männik, K. (Katrin), Metspalu, A. (Andres), Baker, J.H. (Jessica H), Cone, R.D. (Roger D), Esko, T. (Tõnu), DeSocio, J.E. (Janiece E), Hilliard, C.E. (Christopher E), O’Toole, J.K. (Julie K), Pantel, J. (Jacques), Szatkiewicz, J.P. (Jin P), Taico, C. (Chrysecolla), Zerwas, S. (Stephanie), Trace, S.E. (Sara E), Davis, O.S.P. (Oliver S.), Helder, S. (Sietske), Bühren, K. (Katharina), Burghardt, R. (Roland), Imgart, H. (Hartmut), Scherag, A. (Andre), Boni, C. (Claudette), Ramoz, N. (Nicolas), Versini, A. (Audrey), Danner, U.N. (Unna N), de Kove, C. (Carolien), Hendriks, J. (Judith), Koeleman, B.P.C. (Bobby P. C.), Ophoff, R.A. (Roel), Strengman, E. (Eric), Bruson, A. (Alice), Clementi, M. (Maurizio), Degortes, D. (Daniela), Forzan, M. (Monica), Tenconi, E. (Elena), Docampo, E. (Elisa), Jiménez-Murcia, G.E.S. (Geòrgia Escaramí Susana), Lissowska, J. (Jolanta), Rajewski, A. (Andrzej), Szeszenia-Dabrowska, N. (Neonila), Slopien, A. (Agnieszka), Hauser, J. (J.), Karhunen, L. (Leila), Meulenbelt, I. (Ingrid), Slagboom, P.E. (Eline), Tortorella, A. (Alfonso), Maj, M. (Mario), Dedoussis, G.V. (George), Dedoussis, G.V. (G. V.), Koeleman, B.P.C. (Bobby), Gonidakis, F. (Fragiskos), Tziouvas, K. (Konstantinos), Tsitsika, A. (Artemis), Papezova, H. (Hana), Slachtova, L. (Lenka), Martaskova, D. (Debora), Kennedy, J.L., Levitan, R.D. (Robert D), Yilmaz, Z. (Zeynep), Huemer, J. (Julia), Koubek, D. (Doris), Merl, E. (Elisabeth), Wagner, G. (Gudrun), Lichtenstein, P. (Paul), Breen, G. (Gerome), Cohen-Woods, S. (Sarah), Farmer, A.E. (Anne E), Mcguffin, P. (Peter), Cichon, S. (Sven), Giegling, I. (Ina), Herms, S. (Stefan), Rujescu, D. (Dan), Schreiber, S. (Stefan), Wichmann, H.E. (Heinz Erich), Sladek, R. (Rob), Gambaro, G. (Giovanni), Soranzo, N. (Nicole), Julia, A. (Antonio), Marsal, S. (Sara), Rabionet, R. (Raquel), Gaborieau, V. (Valerie), Dick, D.M. (Danielle), Palotie, A. (A.), Ripatti, S. (Samuli), Widen, E., Espeseth, T. (Thomas), Lundervold, A.J. (Astri), Reinvang, I. (Ivar), Steen, V.M. (Vidar), Le Hellard, S. (Stephanie), Mattingsdal, M. (Morten), Ntalla, I. (Ioanna), Bencko, V. (Vladimir), Foretova, L. (Lenka), Janout, V. (Vladimir), Navratilova, M. (Marie), Pinto, D. (Dalila), Scherer, S.W. (Stephen W), Carlberg, L. (Laura), Schosser, A. (Alexandra), Alfredsson, L. (Lars), Pinto, D. (Duane), Scherer, S.W. (Stephen), Padyukov, L. (Leonid), Finan, C. (Chris), Kalsi, G. (Gursharan), Roberts, M. (Marion), Logan, D.W. (Darren W), Peltonen, L. (Leena Johanna), Ritchie, G.R.S. (Graham R.S.), Barrett, J.C. (Jeffrey), Estivill, X. (Xavier), Sullivan, P.F. (Patrick), Anderson, C.A. (Carl A), McGinnis, R. (Ralph), Sambrook, J. (Jennifer), Stephens, J. (Jonathan), Ouwehand, W.H. (Willem), McArdle, P.F. (P. F.), Ring, S.M. (Susan), Strachan, D.P. (David), Alexander, G. (Graeme), Conlon, P.J. (Peter J), Dominiczak, A. (Anna), Duncanson, A. (Audrey), Padyukov, L. (L.), Langford, C. (Cordelia), Lord, G. (Graham), Conlon, P. (Peter), Sandford, R. (Richard), Sheerin, N. (Neil), Vannberg, F.O. (Frederik O), Blackburn, H. (Hannah), Maxwell, A.P. (A.), Edkins, T. (Ted), Gillman, M.W. (Matthew W.), Gray, E. (Emma), Hunt, S.E. (Sarah E), Nengut, S.-G. (Suna-Gumuscu), Potter, S.C. (Simon), Rich, S.S. (Stephen), Simpkin, D. (Douglas), Whittaker, P. (Pamela), Ang, W.Q. (Wei), Atalay, M. (Mustafa), Beijsterveldt, C.E.M. (Toos) van, Bergen, N. (N.), Benke, K. (K.), Berry, D. (Diane), Boomsma, D.I. (Dorret), Bradfield, J.P. (Jonathan), Charoen, P. (Pimphen), Coin, L. (Lachlan), Cooper, C. (C.), Cousminer, D.L. (Diana), Das, S. (Shikta), Elliott, P. (P.), Evans, D.M. (D. M.), Feenstra, B. (B.), Flexeder, C. (Claudia), Frayling, T.M. (Timothy), Freathy, R.M. (Rachel), Gaillard, R. (R.), Geller, F. (Frank), Groen-Blokhuis, M. (Maria), Goh, L.K. (L. K.), Guxens Junyent, M. (Mònica), Hattersley, A.T. (Andrew), Haworth, C.M.A. (Claire M.), Hadley, D. (D.), Heinrich, J. (J.), Hirschhorn, J.N. (Joel), Hocher, B. (Berthold), Holloway, J.W. (J. W.), Holst, J.J., Hottenga, J.J. (Jouke Jan), Horikoshi, M. (Momoko), Huikari, V. (Ville), Hypponen, E. (E.), Iñiguez, C. (C.), Jaddoe, V.W. (V. W.), Jarvelin, M.R. (M. R.), Kaakinen, M. (M.), Kilpeläinen, T.O. (Tuomas), Hypponen, E. (Elina), Kowgier, M. (Matthew), Lakka, T.A. (Timo), Cooper, C. (Charles), Lange, L.A. (Leslie), Lawlor, D.A. (D. A.), Lehtimäki, T. (Terho), Lewin, A. (Alex), Elliott, P. (Paul), Lindi, V. (Virpi), Maggi, R. (Reedik), Feenstra, B. (Bjarke), McCarthy, M.I. (M. I.), Melbye, M. (Mads), Middeldorp, C.M. (Christel), Millwood, I.Y. (Iona), Mohlke, K.L. (Karen), Mook-Kanamori, D.O. (D. O.), Murray, J.C. (Jeffrey), Nivard, M. (Michel), Nohr, C. (Christian), Oken, E. (Emily), Ong, K.K. (K. K.), O'Reilly, P.F. (P. F.), Palmer, C. (Cameron), Panoutsopoulou, K. (K.), Pararajasingham, J. (Jennifer), Pearson, E.R. (E. R.), Pennell, C.E. (Craig), Power, C. (Christopher), Price, T.S. (Thomas), Prokopenko, I. (Inga), Raitakari, O.T. (O. T.), Rodriguez, A. (A.), Salem, R.M. (Rany), Saw, S.M. (S. M.), Sebert, S. (S.), Siitonen, N. (Niina), Jaddoe, V.W.V. (Vincent), Sørensen, T.I.A. (Thorkild), Sovio, U. (Ulla), Lawlor, D.A. (Debbie), Sunyer, J. (J.), Taal, H.R. (Rob), Teo, Y.Y. (Y. Y.), Thiering, E. (Elisabeth), Tiesler, C. (C.), Timpson, N.J. (Nicholas), Uitterlinden, A.G. (André), Valcárcel, B. (Beatriz), Teo, Y.Y. (Yik Ying), White, S.J. (Stefan), Willemsen, G.A.H.M. (Gonneke), Wilson, J.F. (J. F.), Yaghootkar, H. (H.), Elks, C.E. (Cathy), Perry, J.R. (J. R.), Sulem, P. (Patrick), Chasman, D.I. (Daniel), Franceschini, N. (Nora), He, C. (C.), Lunetta, K.L. (Kathryn), Visser, J.A. (Jenny), Byrne, E.M. (E. M.), Gudbjartsson, D.F. (Daniel), Koller, D.L. (Daniel), Kutalik, Z. (Zoltán), Lin, P. (P.), Mangino, M. (Massimo), Byrne, E.M. (Enda), Smith, A.V. (Albert), Stolk, L. (Lisette), Wingerden, S. (Sophie) van, Zhao, J.H. (J. H.), Albrecht, E. (Eva), Corre, T. (Tanguy), Ingelsson, E. (Erik), Hayward, C. (Caroline), Magnusson, P.K. (Patrik), Smith, A.V. (Davey), Chanock, S.J. (Stephen), Warrington, M. (M.), Zgaga, L. (L.), Alavere, H. (Helene), Amin, N. (Najaf), Aspelund, T. (T.), Ulivi, S. (Shelia), Sunyer, J. (Jordi), Berenson, G. (Gerald), Bergmann, S.M. (Sven), Boerwinkle, E. (E.), Buring, J.E. (Julie), Busonero, F. (F.), Barroso, I.E. (Inês), Chanock, S.J. (S. J.), Warrington, N.M. (Nicole), Couper, D.J. (David), Coviello, A.D. (Andrea), Busonero, F., Faire, U. (Ulf) de, de Geus, E.J. (E. J.), Deloukas, P. (Panagiotis), Döring, A. (Angela), Davey Smith, G. (G.), Adamo, P. (Pio) d', Eiriksdottir, G. (Gudny), Geus, E.J.C. (Eco) de, Hagen, K. (Knut), Ferrucci, L. (L.), Folsom, A.R. (A. R.), Foroud, T. (T.), Garcia, M.E. (M.), Gasparini, P. (P.), Gieger, C. (Christian), Gudnason, V. (V.), Folsom, A.R. (Aaron), Hankinson, S.E. (S. E.), Ferreli, L. (Liana), Gasparini, P. (Paolo), Hernandez, D.G. (Dena), Hofman, A. (Albert), Hu, F.B. (F. B.), Illig, T. (T.), Jarvelin, M.-R. (Marjo-Riitta), Johnson, A.D. (Andrew), Karasik, D. (David), Khaw, K.T. (K. T.), Kiel, D.P. (Douglas P.), Kolcic, I. (Ivana), Kraft, P. (Peter), Launer, L.J. (Lenore), Laven, J.S. (J. S.), Li, S. (S.), Liu, J. (J.), Levy, D. (D.), Martin, N.G. (N. G.), Aspelund, T. (Thor), Nalls, M.A. (Michael), Navarro, P. (Pau), Nelis, M. (M.), Ness, A.R. (A. R.), Boerwinkle, E.A. (Eric), Oostra, B.A. (Ben), Peacock, M. (M.), Pare, G. (Guillame), Parker, A.N. (Alex), Pedersen, N.L. (Nancy), Cornelis, M. (Marilyn), Polasek, O. (Ozren), Plump, A.S. (A. S.), Peacock, M. (Munro), Porcu, E. (Eleonora), Rafnar, T. (Thorunn), Rice, J.P. (John), Rivadeneira, F. (F.), Sala, C. (Cinzia), Salomaa, V. (Veikko), Sanna, S. (Serena), Schlessinger, D. (D.), Scuteri, A. (A.), Segrè, A.V. (Ayellet), Foroud, T. (Tatiana), Srinivasan, S.R. (Sathanur), Tammesoo, M.L. (M. L.), Tikkanen, E. (Emmi), Toniolo, D. (Daniela), Scuteri, A. (Angelo), Tryggvadottir, L. (Laufey), Tyrer, J. (J.), Uda, M. (M.), van Dam, R.M. (R. M.), Meurs, J.B.J. (Joyce) van, Vollenweider, P. (Peter), Waeber, G. (Gérard), Wareham, N.J. (Nick), Waterworth, D. (Dawn), Weedon, M.N. (Michael), Wright, A.F. (Alan), Young, L. (L.), Zhai, G. (G.), Zhuang, W.V. (W. V.), Bierut, L.J. (L. J.), Boyd, H.A. (H. A.), Crisponi, L. (Laura), Demerath, E.W. (E. W.), Duijn, C.M. (Cornelia) van, Econs, M.J. (M. J.), Harris, T.B. (Tamara), Bierut, L.J. (Laura), Loos, R.J.F. (Ruth), Ridker, P.M. (Paul), Demerath, E.W. (Ellen), Streeten, E.A. (Elizabeth), Econs, M.J. (Michael), Thorsteinsdottir, U. (Unnur), Widen, E. (E.), Murabito, J. (Joanne), Ness, A.R. (Andrew), Spector, T.D. (Timothy), Crawford, S. (Steve), Crow, S. (Scott), Fichter, M.M. (M. M.), Halmi, K.A. (K. A.), Palotie, A. (Aarno), La Via, M. (Maria), Mitchell, J. (James), Strober, M. (Michael), Rotondo, A. (Alessandro), Woodside, D.B. (D Blake), Keel, P. (Pamela), Lilenfeld, L. (Lisa), Rivadeneira Ramirez, F. (Fernando), Magistretti, P. (Pierre), Montgomery, G.W. (G. W.), Hinney, A. (Anke), Kesselmeier, M. (M.), Jall, S. (S.), Volckmar, A.-L. (A. L.), Föcker, M. (M.), Antel, J. (J.), Heid, I.M. (Iris), Winkler, T.W. (Thomas W.), Grant, S.F.A. (S. F.A.), Guo, Y. (Yongli), Bergen, A.W. (Andrew), Grant, S.F.A. (Struan), Berrettini, W. (Wade), Hakonarson, H. (Hakon), Herpertz-Dahlmann, B. (B.), De Zwaan, M. (M.), Herzog, W. (W.), Ehrlich, S.M. (Stefan), Zipfel, S. (S.), Egberts, K. (Karin), Adan, R. (R.), Brandys, M. (M.), Elburg, A.A. (Annemarie) van, Boraska Perica, V. (V.), Müller, T.D., Tschöp, M.H. (M. H.), Zeggini, E. (Eleftheria), Bulik, C.M. (C. M.), Collier, D.A. (David), Scherag, A. (A.), Hebebrand, J. (J.), Tschop, M. (Matthias), Floyd, J. (Jamie), Thornton, L.M. (Laura), Huckins, L.M. (Laura M), Southam, L. (Lorraine), Rayner, N.W. (Nigel William), Tachmazidou, I. (Ioanna), Klump, K.L. (K. L.), Treasure, J. (Janet), Lewis, C.M. (Cathryn), Schmidt, U. (Ulrike), Tozzi, F. (Federica), Iezebrink, K. (Kirsty), Gorwood, P. (Philip), Kas, M.J.H. (Martien), Favaro, A. (Angela), Santonastaso, P. (Paolo), Fernández-Aranda, F. (Fernando), Gratacos, M. (Monica), Rybakowski, F. (Filip), Dmitrzak-Weglarz, M. (Monika), Kaprio, J. (Jaakko), Keski-Rahkonen, A. (Anna), Raevuori-Helkamaa, A. (Anu), Furth, E.F. (Eric) van, Slof-Op’t Landt, M.C.T. (Margarita C. T.), Hudson, J.I. (James I), Knudsen, G.P.S. (Gun Peggy S.), Monteleone, P. (Palmiero), Kaplan, A.S. (Allan S), Karwautz, A. (Andreas), Li, D. (Dong), Komaki, G. (Gen), Ando, T. (Tetsuya), Inoko, H. (Hidetoshi), Esko, T. (T.), Fischer, K. (Krista), Männik, K. (Katrin), Metspalu, A. (Andres), Baker, J.H. (Jessica H), Cone, R.D. (Roger D), Esko, T. (Tõnu), DeSocio, J.E. (Janiece E), Hilliard, C.E. (Christopher E), O’Toole, J.K. (Julie K), Pantel, J. (Jacques), Szatkiewicz, J.P. (Jin P), Taico, C. (Chrysecolla), Zerwas, S. (Stephanie), Trace, S.E. (Sara E), Davis, O.S.P. (Oliver S.), Helder, S. (Sietske), Bühren, K. (Katharina), Burghardt, R. (Roland), Imgart, H. (Hartmut), Scherag, A. (Andre), Boni, C. (Claudette), Ramoz, N. (Nicolas), Versini, A. (Audrey), Danner, U.N. (Unna N), de Kove, C. (Carolien), Hendriks, J. (Judith), Koeleman, B.P.C. (Bobby P. C.), Ophoff, R.A. (Roel), Strengman, E. (Eric), Bruson, A. (Alice), Clementi, M. (Maurizio), Degortes, D. (Daniela), Forzan, M. (Monica), Tenconi, E. (Elena), Docampo, E. (Elisa), Jiménez-Murcia, G.E.S. (Geòrgia Escaramí Susana), Lissowska, J. (Jolanta), Rajewski, A. (Andrzej), Szeszenia-Dabrowska, N. (Neonila), Slopien, A. (Agnieszka), Hauser, J. (J.), Karhunen, L. (Leila), Meulenbelt, I. (Ingrid), Slagboom, P.E. (Eline), Tortorella, A. (Alfonso), Maj, M. (Mario), Dedoussis, G.V. (George), Dedoussis, G.V. (G. V.), Koeleman, B.P.C. (Bobby), Gonidakis, F. (Fragiskos), Tziouvas, K. (Konstantinos), Tsitsika, A. (Artemis), Papezova, H. (Hana), Slachtova, L. (Lenka), Martaskova, D. (Debora), Kennedy, J.L., Levitan, R.D. (Robert D), Yilmaz, Z. (Zeynep), Huemer, J. (Julia), Koubek, D. (Doris), Merl, E. (Elisabeth), Wagner, G. (Gudrun), Lichtenstein, P. (Paul), Breen, G. (Gerome), Cohen-Woods, S. (Sarah), Farmer, A.E. (Anne E), Mcguffin, P. (Peter), Cichon, S. (Sven), Giegling, I. (Ina), Herms, S. (Stefan), Rujescu, D. (Dan), Schreiber, S. (Stefan), Wichmann, H.E. (Heinz Erich), Sladek, R. (Rob), Gambaro, G. (Giovanni), Soranzo, N. (Nicole), Julia, A. (Antonio), Marsal, S. (Sara), Rabionet, R. (Raquel), Gaborieau, V. (Valerie), Dick, D.M. (Danielle), Palotie, A. (A.), Ripatti, S. (Samuli), Widen, E., Espeseth, T. (Thomas), Lundervold, A.J. (Astri), Reinvang, I. (Ivar), Steen, V.M. (Vidar), Le Hellard, S. (Stephanie), Mattingsdal, M. (Morten), Ntalla, I. (Ioanna), Bencko, V. (Vladimir), Foretova, L. (Lenka), Janout, V. (Vladimir), Navratilova, M. (Marie), Pinto, D. (Dalila), Scherer, S.W. (Stephen W), Carlberg, L. (Laura), Schosser, A. (Alexandra), Alfredsson, L. (Lars), Pinto, D. (Duane), Scherer, S.W. (Stephen), Padyukov, L. (Leonid), Finan, C. (Chris), Kalsi, G. (Gursharan), Roberts, M. (Marion), Logan, D.W. (Darren W), Peltonen, L. (Leena Johanna), Ritchie, G.R.S. (Graham R.S.), Barrett, J.C. (Jeffrey), Estivill, X. (Xavier), Sullivan, P.F. (Patrick), Anderson, C.A. (Carl A), McGinnis, R. (Ralph), Sambrook, J. (Jennifer), Stephens, J. (Jonathan), Ouwehand, W.H. (Willem), McArdle, P.F. (P. F.), Ring, S.M. (Susan), Strachan, D.P. (David), Alexander, G. (Graeme), Conlon, P.J. (Peter J), Dominiczak, A. (Anna), Duncanson, A. (Audrey), Padyukov, L. (L.), Langford, C. (Cordelia), Lord, G. (Graham), Conlon, P. (Peter), Sandford, R. (Richard), Sheerin, N. (Neil), Vannberg, F.O. (Frederik O), Blackburn, H. (Hannah), Maxwell, A.P. (A.), Edkins, T. (Ted), Gillman, M.W. (Matthew W.), Gray, E. (Emma), Hunt, S.E. (Sarah E), Nengut, S.-G. (Suna-Gumuscu), Potter, S.C. (Simon), Rich, S.S. (Stephen), Simpkin, D. (Douglas), Whittaker, P. (Pamela), Ang, W.Q. (Wei), Atalay, M. (Mustafa), Beijsterveldt, C.E.M. (Toos) van, Bergen, N. (N.), Benke, K. (K.), Berry, D. (Diane), Boomsma, D.I. (Dorret), Bradfield, J.P. (Jonathan), Charoen, P. (Pimphen), Coin, L. (Lachlan), Cooper, C. (C.), Cousminer, D.L. (Diana), Das, S. (Shikta), Elliott, P. (P.), Evans, D.M. (D. M.), Feenstra, B. (B.), Flexeder, C. (Claudia), Frayling, T.M. (Timothy), Freathy, R.M. (Rachel), Gaillard, R. (R.), Geller, F. (Frank), Groen-Blokhuis, M. (Maria), Goh, L.K. (L. K.), Guxens Junyent, M. (Mònica), Hattersley, A.T. (Andrew), Haworth, C.M.A. (Claire M.), Hadley, D. (D.), Heinrich, J. (J.), Hirschhorn, J.N. (Joel), Hocher, B. (Berthold), Holloway, J.W. (J. W.), Holst, J.J., Hottenga, J.J. (Jouke Jan), Horikoshi, M. (Momoko), Huikari, V. (Ville), Hypponen, E. (E.), Iñiguez, C. (C.), Jaddoe, V.W. (V. W.), Jarvelin, M.R. (M. R.), Kaakinen, M. (M.), Kilpeläinen, T.O. (Tuomas), Hypponen, E. (Elina), Kowgier, M. (Matthew), Lakka, T.A. (Timo), Cooper, C. (Charles), Lange, L.A. (Leslie), Lawlor, D.A. (D. A.), Lehtimäki, T. (Terho), Lewin, A. (Alex), Elliott, P. (Paul), Lindi, V. (Virpi), Maggi, R. (Reedik), Feenstra, B. (Bjarke), McCarthy, M.I. (M. I.), Melbye, M. (Mads), Middeldorp, C.M. (Christel), Millwood, I.Y. (Iona), Mohlke, K.L. (Karen), Mook-Kanamori, D.O. (D. O.), Murray, J.C. (Jeffrey), Nivard, M. (Michel), Nohr, C. (Christian), Oken, E. (Emily), Ong, K.K. (K. K.), O'Reilly, P.F. (P. F.), Palmer, C. (Cameron), Panoutsopoulou, K. (K.), Pararajasingham, J. (Jennifer), Pearson, E.R. (E. R.), Pennell, C.E. (Craig), Power, C. (Christopher), Price, T.S. (Thomas), Prokopenko, I. (Inga), Raitakari, O.T. (O. T.), Rodriguez, A. (A.), Salem, R.M. (Rany), Saw, S.M. (S. M.), Sebert, S. (S.), Siitonen, N. (Niina), Jaddoe, V.W.V. (Vincent), Sørensen, T.I.A. (Thorkild), Sovio, U. (Ulla), Lawlor, D.A. (Debbie), Sunyer, J. (J.), Taal, H.R. (Rob), Teo, Y.Y. (Y. Y.), Thiering, E. (Elisabeth), Tiesler, C. (C.), Timpson, N.J. (Nicholas), Uitterlinden, A.G. (André), Valcárcel, B. (Beatriz), Teo, Y.Y. (Yik Ying), White, S.J. (Stefan), Willemsen, G.A.H.M. (Gonneke), Wilson, J.F. (J. F.), Yaghootkar, H. (H.), Elks, C.E. (Cathy), Perry, J.R. (J. R.), Sulem, P. (Patrick), Chasman, D.I. (Daniel), Franceschini, N. (Nora), He, C. (C.), Lunetta, K.L. (Kathryn), Visser, J.A. (Jenny), Byrne, E.M. (E. M.), Gudbjartsson, D.F. (Daniel), Koller, D.L. (Daniel), Kutalik, Z. (Zoltán), Lin, P. (P.), Mangino, M. (Massimo), Byrne, E.M. (Enda), Smith, A.V. (Albert), Stolk, L. (Lisette), Wingerden, S. (Sophie) van, Zhao, J.H. (J. H.), Albrecht, E. (Eva), Corre, T. (Tanguy), Ingelsson, E. (Erik), Hayward, C. (Caroline), Magnusson, P.K. (Patrik), Smith, A.V. (Davey), Chanock, S.J. (Stephen), Warrington, M. (M.), Zgaga, L. (L.), Alavere, H. (Helene), Amin, N. (Najaf), Aspelund, T. (T.), Ulivi, S. (Shelia), Sunyer, J. (Jordi), Berenson, G. (Gerald), Bergmann, S.M. (Sven), Boerwinkle, E. (E.), Buring, J.E. (Julie), Busonero, F. (F.), Barroso, I.E. (Inês), Chanock, S.J. (S. J.), Warrington, N.M. (Nicole), Couper, D.J. (David), Coviello, A.D. (Andrea), Busonero, F., Faire, U. (Ulf) de, de Geus, E.J. (E. J.), Deloukas, P. (Panagiotis), Döring, A. (Angela), Davey Smith, G. (G.), Adamo, P. (Pio) d', Eiriksdottir, G. (Gudny), Geus, E.J.C. (Eco) de, Hagen, K. (Knut), Ferrucci, L. (L.), Folsom, A.R. (A. R.), Foroud, T. (T.), Garcia, M.E. (M.), Gasparini, P. (P.), Gieger, C. (Christian), Gudnason, V. (V.), Folsom, A.R. (Aaron), Hankinson, S.E. (S. E.), Ferreli, L. (Liana), Gasparini, P. (Paolo), Hernandez, D.G. (Dena), Hofman, A. (Albert), Hu, F.B. (F. B.), Illig, T. (T.), Jarvelin, M.-R. (Marjo-Riitta), Johnson, A.D. (Andrew), Karasik, D. (David), Khaw, K.T. (K. T.), Kiel, D.P. (Douglas P.), Kolcic, I. (Ivana), Kraft, P. (Peter), Launer, L.J. (Lenore), Laven, J.S. (J. S.), Li, S. (S.), Liu, J. (J.), Levy, D. (D.), Martin, N.G. (N. G.), Aspelund, T. (Thor), Nalls, M.A. (Michael), Navarro, P. (Pau), Nelis, M. (M.), Ness, A.R. (A. R.), Boerwinkle, E.A. (Eric), Oostra, B.A. (Ben), Peacock, M. (M.), Pare, G. (Guillame), Parker, A.N. (Alex), Pedersen, N.L. (Nancy), Cornelis, M. (Marilyn), Polasek, O. (Ozren), Plump, A.S. (A. S.), Peacock, M. (Munro), Porcu, E. (Eleonora), Rafnar, T. (Thorunn), Rice, J.P. (John), Rivadeneira, F. (F.), Sala, C. (Cinzia), Salomaa, V. (Veikko), Sanna, S. (Serena), Schlessinger, D. (D.), Scuteri, A. (A.), Segrè, A.V. (Ayellet), Foroud, T. (Tatiana), Srinivasan, S.R. (Sathanur), Tammesoo, M.L. (M. L.), Tikkanen, E. (Emmi), Toniolo, D. (Daniela), Scuteri, A. (Angelo), Tryggvadottir, L. (Laufey), Tyrer, J. (J.), Uda, M. (M.), van Dam, R.M. (R. M.), Meurs, J.B.J. (Joyce) van, Vollenweider, P. (Peter), Waeber, G. (Gérard), Wareham, N.J. (Nick), Waterworth, D. (Dawn), Weedon, M.N. (Michael), Wright, A.F. (Alan), Young, L. (L.), Zhai, G. (G.), Zhuang, W.V. (W. V.), Bierut, L.J. (L. J.), Boyd, H.A. (H. A.), Crisponi, L. (Laura), Demerath, E.W. (E. W.), Duijn, C.M. (Cornelia) van, Econs, M.J. (M. J.), Harris, T.B. (Tamara), Bierut, L.J. (Laura), Loos, R.J.F. (Ruth), Ridker, P.M. (Paul), Demerath, E.W. (Ellen), Streeten, E.A. (Elizabeth), Econs, M.J. (Michael), Thorsteinsdottir, U. (Unnur), Widen, E. (E.), Murabito, J. (Joanne), Ness, A.R. (Andrew), Spector, T.D. (Timothy), Crawford, S. (Steve), Crow, S. (Scott), Fichter, M.M. (M. M.), Halmi, K.A. (K. A.), Palotie, A. (Aarno), La Via, M. (Maria), Mitchell, J. (James), Strober, M. (Michael), Rotondo, A. (Alessandro), Woodside, D.B. (D Blake), Keel, P. (Pamela), Lilenfeld, L. (Lisa), Rivadeneira Ramirez, F. (Fernando), Magistretti, P. (Pierre), and Montgomery, G.W. (G. W.)
Abstract: The maintenance of normal body weight is disrupted in patients with anorexia nervosa (AN) for prolonged periods of time. Prior to the onset of AN, premorbid body mass index (BMI) spans the entire range from underweight to obese. After recovery, patients have reduced rates of overweight and obesity. As such, loci involved in body weight regulation may also be relevant for AN and vice versa. Our primary analysis comprised a cross-trait analysis of the 1000 single-nucleotide polymorphisms (SNPs) with the lowest P-values in a genome-wide association meta-analysis (GWAMA) of AN (GCAN) for evidence of association in the largest published GWAMA for BMI (GIANT). Subsequently we performed sex-stratified analyses for these 1000 SNPs. Functional ex vivo studies on four genes ensued. Lastly, a look-up of GWAMA-derived BMI-related loci was performed in the AN GWAMA. We detected significant associations (P-values <5 × 10-5, Bonferroni-corrected P<0.05) for nine SNP alleles at three independent loci. Interestingly, all AN susceptibility alleles were consistently associated with increased BMI. None of the genes (chr. 10: CTBP2, chr. 19: CCNE1, chr. 2: CARF and NBEAL1; the latter is a region with high linkage disequilibrium) nearest to these SNPs has previously been associated with AN or obesity. Sex-stratified analyses revealed that the strongest BMI signal originated predominantly from females (chr. 10 rs1561589; Poverall: 2.47 × 10-06/Pfemales: 3.45 × 10-07/Pmales: 0.043). Functional ex vivo studies in mice revealed reduced hypothalamic expression of Ctbp2 and Nbeal1 after fasting. Hypothalamic expression of Ctbp2 was increased in diet-induced obese (DIO) mice as compared with age-matched lean controls. We observed no evidence for associations for the look-up of BMI-related loci in the AN GWAMA. A cross-trait analysis of AN and BMI loci revealed variants at three chromosomal loci with potential joint impact. The chromosome 10 locus is particularly promising given that the associa
Published: 2017
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10. International Osteoporosis Foundation and European Calcified Tissue Society Working Group. Recommendations for the screening of adherence to oral bisphosphonates

Author: Diez-Perez, A. (Adolfo), Naylor, K.E., Abrahamsen, B., Agnusdei, D., Brandi, M.L., Cooper, C. (Charles), Dennison, E.M. (Elaine), Eriksen, E.F., Gold, D.T., Guañabens, N., Hadji, P. (Peyman), Hiligsmann, M. (Mickael), Horne, R., Josse, R., Kanis, J.A. (John), Obermayer-Pietsch, B. (Barbara), Prieto-Alhambra, D., Reginster, J-Y. (Jean-Yves), Rizzoli, R., Silverman, S. (Stuart), Zillikens, M.C. (Carola), Eastell, R. (Richard), Diez-Perez, A. (Adolfo), Naylor, K.E., Abrahamsen, B., Agnusdei, D., Brandi, M.L., Cooper, C. (Charles), Dennison, E.M. (Elaine), Eriksen, E.F., Gold, D.T., Guañabens, N., Hadji, P. (Peyman), Hiligsmann, M. (Mickael), Horne, R., Josse, R., Kanis, J.A. (John), Obermayer-Pietsch, B. (Barbara), Prieto-Alhambra, D., Reginster, J-Y. (Jean-Yves), Rizzoli, R., Silverman, S. (Stuart), Zillikens, M.C. (Carola), and Eastell, R. (Richard)
Abstract: Summary: Adherence to oral bisphosphonates is low. A screening strategy is proposed based on the response of biochemical markers of bone turnover after 3 months of therapy. If no change is observed, the clinician should reassess the adherence to the treatment and also other potential issues with the drug. Introduction: Low adherence to oral bisphosphonates is a common problem that jeopardizes the efficacy of treatment of osteoporosis. No clear screening strategy for the assessment of compliance is widely accepted in these patients. Methods: The International Osteoporosis Foundation and the European Calcified Tissue Society have convened a working group to propose a screening strategy to detect a lack of adherence to these drugs. The question to answer was whether the bone turnover markers (BTMs) PINP and CTX can be used to identify low adherence in patients with postmenopausal osteoporosis initiating oral bisphosphonates for osteoporosis. The findings of the TRIO study specifically address this question and were used as the basis for testing the hypothesis. Results: Based on the findings of the TRIO study, specifically addressing this question, the working group recommends measuring PINP and
Published: 2017
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11. Identification of 153 new loci associated with heel bone mineral density and functional involvement of GPC6 in osteoporosis

Author: Kemp, J.P. (John), Morris, J.A. (John A.), Medina-Gomez, M.C. (Carolina), Forgetta, V. (Vincenzo), Warrington, N.M. (Nicole), Youlten, S.E. (Scott E.), Zheng, J. (Jie), Gregson, C.L. (Celia L.), Grundberg, E. (Elin), Trajanoska, K. (Katerina), Logan, J.G. (John G.), Pollard, A.S. (Andrea S.), Sparkes, P.C. (Penny C.), Ghirardello, E.J. (Elena J.), Allen, R. (Rebecca), Leitch, V.D. (Victoria D.), Butterfield, N.C. (Natalie C.), Komla-Ebri, D. (Davide), Adoum, A.-T. (Anne-Tounsia), Curry, K.F. (Katharine F.), White, J.K. (Jacqueline K.), Kussy, F. (Fiona), Greenlaw, K.M. (Keelin M.), Xu, C. (Changjiang), Harvey, N.C. (Nicholas), Cooper, C. (Charles), Adams, D.J. (David J.), Greenwood, C.M.T. (Celia), Maurano, M.T. (Matthew T.), Kaptoge, S. (Stephen), Rivadeneira, F. (Fernando), Tobias, J.H. (Jon), Croucher, P.I., Ackert-Bicknell, C.L. (Cheryl L.), Bassett, J.H.D. (J. H. Duncan), Williams, G. (Graham), Richards, J.B. (Brent), Evans, D.M. (David M.), Kemp, J.P. (John), Morris, J.A. (John A.), Medina-Gomez, M.C. (Carolina), Forgetta, V. (Vincenzo), Warrington, N.M. (Nicole), Youlten, S.E. (Scott E.), Zheng, J. (Jie), Gregson, C.L. (Celia L.), Grundberg, E. (Elin), Trajanoska, K. (Katerina), Logan, J.G. (John G.), Pollard, A.S. (Andrea S.), Sparkes, P.C. (Penny C.), Ghirardello, E.J. (Elena J.), Allen, R. (Rebecca), Leitch, V.D. (Victoria D.), Butterfield, N.C. (Natalie C.), Komla-Ebri, D. (Davide), Adoum, A.-T. (Anne-Tounsia), Curry, K.F. (Katharine F.), White, J.K. (Jacqueline K.), Kussy, F. (Fiona), Greenlaw, K.M. (Keelin M.), Xu, C. (Changjiang), Harvey, N.C. (Nicholas), Cooper, C. (Charles), Adams, D.J. (David J.), Greenwood, C.M.T. (Celia), Maurano, M.T. (Matthew T.), Kaptoge, S. (Stephen), Rivadeneira, F. (Fernando), Tobias, J.H. (Jon), Croucher, P.I., Ackert-Bicknell, C.L. (Cheryl L.), Bassett, J.H.D. (J. H. Duncan), Williams, G. (Graham), Richards, J.B. (Brent), and Evans, D.M. (David M.)
Abstract: Osteoporosis is a common disease diagnosed primarily by measurement of bone mineral density (BMD). We undertook a genomewide association study (GWAS) in 142,487 individuals from the UK Biobank to identify loci associated with BMD as estimated by quantitative ultrasound of the heel. We identified 307 conditionally independent single-nucleotide polymorphisms (SNPs) that attained genome-wide significance at 203 loci, explaining approximately 12% of the phenotypic variance. These included 153 previously unreported loci, and several rare variants with large effect sizes. To investigate the underlying mechanisms, we undertook (1) bioinformatic, functional genomic annotation and human osteoblast expression studies; (2) gene-function prediction; (3) skeletal phenotyping of 120 knockout mice with deletions of genes adjacent to lead independent SNPs; and (4) analysis of gene expression in mouse osteoblasts, osteocytes and osteoclasts. The results implicate GPC6 as a novel determinant of BMD, and also identify abnormal skeletal phenotypes in knockout mice associated with a further 100 prioritized genes.
Published: 2017
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12. Worldwide trends in diabetes since 1980: A pooled analysis of 751 population-based studies with 4.4 million participants

Author: Zhou, B. (Bin), Lu, Y. (Yuan), Hajifathalian, K. (Kaveh), Bentham, J. (James), Di Cesare, M. (Mariachiara), Danaei, G. (Goodarz), Bixby, H. (Honor), Cowan, M.J. (Melanie J.), Ali, M.K. (Mohammed), Taddei, C. (Cristina), Lo, W.-C. (Wei-Cheng), Reis-Santos, B. (Barbara), Stevens, G.A. (Gretchen A.), Riley, L.M. (Leanne M.), Miranda, J.J. (J. Jaime), Bjerregaard, P. (Peter), Rivera, J.A. (Juan A.), Fouad, H.M. (Heba M.), Ma, G. (Guansheng), Mbanya, J.C.N. (Jean Claude N.), McGarvey, S.T. (Stephen T.), Mohan, V. (Viswanathan), Onat, A. (Altan), Pilav, A. (Aida), Ramachandran, A. (Ambady), Ben Romdhane, H. (Habiba), Paciorek, C.J. (Christopher J.), Bennett, J.E. (James E.), Ezzati, M. (Majid), Abdeen, Z.A. (Ziad A.), Kadir, K.A. (Khalid Abdul), Abu-Rmeileh, N.M. (Niveen M.), Acosta-Cazares, B. (Benjamin), Adams, R. (Robert), Aekplakorn, W. (Wichai), Aguilar-Salinas, C.A. (Carlos), Agyemang, C.O. (Charles), Ahmadvand, A. (Alireza), Al-Othman, A.R. (Amani Rashed), Alkerwi, A. (Ala'a), Amouyel, P. (Philippe), Amuzu, A. (Antoinette), Bo Andersen, L. (Lars), Anderssen, S.A. (Sigmund A.), Anjana, R.M. (Ranjit Mohan), Aounallah-Skhiri, H. (Hajer), Aris, T. (Tahir), Arlappa, N. (Nimmathota), Arveiler, D. (Dominique), Assah, F.K. (Felix K.), Avdicová, M. (Mária), Azizi, J. (Joshan), Balakrishna, N. (Nagalla), Bandosz, P. (Piotr), Barbagallo, C.M. (Carlo M.), Barceló, A. (Alberto), Batieha, A.M. (Anwar M.), Baur, L.A. (Louise A.), Benet, M. (Mikhail), Bernabe-Ortiz, A. (Antonio), Bharadwaj, S. (Sumit), Bhargava, S.K. (Santosh K.), Bi, Y. (Yufang), Bjertness, E. (Espen), Bjertness, M.B. (Marius B.), Björkelund, C. (Cecilia), Blokstra, A. (Anneke), Bo, S. (Simona), Boehm, B.O. (Bernhard), Boissonnet, C.P. (Carlos P.), Bovet, P. (Pascal), Brajkovich, I. (Imperia), Breckenkamp, J. (Juergen), Brenner, H. (Hermann), Brewster, L.M. (Lizzy), Brian, G.R. (Garry R.), Bruno, G. (Graziella), Bugge, A. (Anna), De León, A.C. (Antonio Cabrera), Can, G. (Günay), Cåndido, A.P.C. (Ana Paula C.), Capuano, V. (Vincenzo), Carlsson, A.C. (Axel C.), Carvalho, M.J. (Maria J.), Casanueva, F.F. (Felipe F.), Casas, J.P. (Juan Pablo), Caserta, C.A. (Carmelo A.), Castetbon, K., Chamukuttan, S. (Snehalatha), Chaturvedi, N. (Nishi), Chen, C.-J. (Chien-Jen), Chen, F. (Fangfang), Chen, S. (Shuohua), Cheng, C.-Y. (Ching-Yu), Chetrit, A. (Angela), Chiou, S.-T. (Shu-Ti), Cho, Y. (Yumi), Chudek, J. (Jerzy), Cifkova, R. (Renata), Claessens, F., Concin, H. (Hans), Cooper, C. (Charles), Cooper, R. (Rachel), Costanzo, S. (Simona), Cottel, D. (Dominique), Cowell, C. (Chris), Crujeiras, A.B. (Ana B.), D'Arrigo, G. (Graziella), Dallongeville, J., Dankner, R. (Rachel), Dauchet, L. (Luc), De Gaetano, G. (Giovanni), De Henauw, S. (Stefaan), Deepa, M. (Mohan), Dehghan, A. (Abbas), Deschamps, V. (Valerie), Dhana, K. (Klodian), Di Castelnuovo, A.F. (Augusto F.), Djalalinia, S. (Shirin), Doua, K. (Kouamelan), Drygas, W. (Wojciech), Du, Y. (Yong), Dzerve, V. (Vilnis), Egbagbe, E.E. (Eruke E.), Eggertsen, R. (Robert), El Ati, J. (Jalila), Elosua, R. (Roberto), Erasmus, R.T. (Rajiv T.), Erem, C. (Cihangir), Ergor, G. (Gul), Eriksen, L. (Louise), Escobedo-De La Peña, J. (Jorge), Fall, C.H. (Caroline H.), Farzadfar, F. (Farshad), Felix-Redondo, F.J. (Francisco J.), Ferguson, T.S. (Trevor S.), Fernández-Bergés, D. (Daniel), Ferrari, M. (Marika), Ferreccio, C. (Catterina), Feskens, E.J.M. (Edith), Finn, J.D. (Joseph D.), Föger, B. (Bernhard), Foo, L.H. (Leng Huat), Forslund, A.-S. (Ann-Sofie), Francis, D.K. (Damian K.), Do Carmo Franco, M. (Maria), Franco, O.H. (Oscar), Frontera, G. (Guillermo), Furusawa, T. (Takuro), Gaciong, Z. (Zbigniew), Garnett, S.P. (Sarah P.), Gaspoz, J.-M. (Jean-Michel), Gasull, M. (Magda), Gates, L. (Louise), Geleijnse, J.M. (Marianne), Ghasemian, A. (Anoosheh), Ghimire, A. (Anup), Giampaoli, S. (Simona), Gianfagna, F. (Francesco), Giovannelli, J. (Jonathan), Giwercman, A. (Aleksander), Gross, M., Rivas, J.P.G. (Juan P. González), Gorbea, M.B. (Mariano Bonet), Gottrand, F. (Frederic), Grafnetter, D. (Dušan), Grodzicki, T. (Tomasz), Grøntved, A. (Anders), Gruden, G. (Grabriella), Gu, D. (Dongfeng), Guan, O.P. (Ong Peng), Guerrero, R. (Ramiro), Guessous, I. (Idris), Guimaraes, A.L. (Andre L.), Gutierrez, L. (Laura), Hambleton, I.R. (Ian R.), Hardy, R., Kumar, R.H. (Rachakulla Hari), Hata, J. (Jun), He, J. (Jiang), Heidemann, C. (Christin), Herrala, S. (Sauli), Hihtaniemi, I.T. (Ilpo Tapani), Ho, S.Y. (Sai Yin), Ho, S.C. (Suzanne C.), Hofman, A. (Albert), Hormiga, C.M. (Claudia M.), Horta, B.L. (Bernardo L.), Houti, L. (Leila), Howitt, C. (Christina), Htay, T.T. (Thein Thein), Htet, A.S. (Aung Soe), Htike, M.M.T. (Maung Maung Than), Hu, Y. (Yang), Hussieni, A.S. (Abdullatif S.), Huybrechts, I. (Inge), Hwalla, N. (Nahla), Iacoviello, L. (Licia), Iannone, A.G. (Anna G.), Ibrahim, M.M. (M. Mohsen), Ikeda, N. (Nayu), Ikram, M.A. (M. Arfan), Irazola, V. (Vilma), Islam, M. (Muhammad), Iwasaki, M. (Masanori), Jacobs, J.M. (Jeremy M.), Jafar, T.H. (Tazeen), Jamil, K.M. (Kazi M.), Jasienska, G. (Grazyna), Jiang, C.Q. (Chao Qiang), Jonas, J.B., Joshi, P. (Pradeep), Kafatos, A. (Anthony), Kalter-Leibovici, O. (Ofra), Kasaeian, A. (Amir), Katz, J. (Joanne), Kaur, P. (Prabhdeep), Kavousi, M. (Maryam), Keinanen-Kiukaanniemi, S. (Sirkka), Kelishadi, R. (Roya), Kengne, A.P. (Andre Pascal), Kersting, M. (Mathilde), Khader, Y.S. (Yousef Saleh), Khalili, D. (Davood), Khang, Y.-H. (Young-Ho), Kiechl, S. (Stefan), Kim, J. (Jeongseon), Kolsteren, P. (Patrick), Korrovits, P. (Paul), Kratzer, W. (Wolfgang), Kromhout, D. (Daan), Kujala, U.M. (Urho), Kula, K. (Krzysztof), Kyobutungi, C. (Catherine), Laatikainen, T. (Tiina), Lachat, C. (Carl), Laid, Y. (Youcef), Lam, T.H. (Tai Hing), Landrove, O. (Orlando), Lanska, V. (Vera), Lappas, G. (Georg), Laxmaiah, A. (Avula), Leclercq, C. (Catherine), Lee, J. (Jeannette), Lee, J. (Jeonghee), Lehtimäki, T. (Terho), Lekhraj, R. (Rampal), León-Muñoz, L.M. (Luz M.), Li, Y. (Yanping), Lim, W.-Y. (Wei-Yen), Lima-Costa, M.F. (M. Fernanda), Lin, H.-H. (Hsien-Ho), Lin, X. (Xu), Lissner, L. (Lauren), Lorbeer, R. (Roberto), Lozano, J.E. (José Eugenio), Luksiene, D. (Dalia), Lundqvist, A. (Annamari), Lytsy, P. (Per), Machado-Coelho, G.L.L. (George L.L.), Machi, S. (Suka), Maggi, S. (Stefania), Magliano, D.J., Makdisse, M. (Marcia), Rao, K.M. (Kodavanti Mallikharjuna), Manios, Y., Manzato, E. (Enzo), Margozzini, P. (Paula), Marques-Vidal, P. (Pedro), Martorell, R. (Reynaldo), Masoodi, S.R. (Shariq R.), Mathiesen, E.B. (Ellisiv), Matsha, T.E. (Tandi E.), McFarlane, S.R. (Shelly R.), McLachlan, S. (Stela), McNulty, B.A. (Breige A.), Mediene-Benchekor, S. (Sounnia), Meirhaeghe, A. (Aline), Menezes, A.M.B. (Ana Maria B.), Merat, S. (Shahin), Meshram, I.I. (Indrapal I.), Mi, J. (Jie), Miquel, J.F. (Juan Francisco), Mohamed, M.K. (Mostafa K.), Mohammad, K. (Kazem), Mohammadifard, N. (Noushin), Mohd Yusoff, M.F. (Muhammad Fadhli), Møller, N.C. (Niels C.), Molnár, D. (Dénes), Mondo, C.K. (Charles K.), Morejon, A. (Alain), Moreno, L.A. (Luis A.), Morgan, K. (Karen), Moschonis, G., Mossakowska, M. (Malgorzata), Mostafa, A. (Aya), Mota, J. (Jorge), Motta, J. (Jorge), Mu, T.T. (Thet Thet), Muiesan, M.L. (Maria Lorenza), Müller-Nurasyid, M. (Martina), Mursu, J. (Jaakko), Nagel, G. (Gabriele), Námešná, J. (Jana), Nang, E.E.K. (Ei Ei K.), Nangia, M. (Monika), Navarrete-Muñoz, E.M., Ndiaye, N.C. (Ndeye Coumba), Nenko, I. (Ilona), Nervi, F. (Flavio), Nguyen, N.D. (Nguyen D.), Nguyen, Q.N. (Quang Ngoc), Nieto-Martínez, R.E. (Ramfis E.), Ning, G. (Guang), Ninomiya, T. (Toshiharu), Noale, M. (Marianna), Noto, D. (Davide), Al Nsour, M. (Mohannad), Ochoa-Avilés, A.M. (Angélica M.), Oh, K. (Kyungwon), Ordunez, P. (Pedro), Osmond, C. (Clive), Otero, J.A. (Johanna A.), Owusu-Dabo, E. (Ellis), Pahomova, E. (Elena), Palmieri, L. (Luigi), Panda-Jonas, S. (Songhomitra), Panza, F. (Francesco), Parsaeian, M. (Mahboubeh), Peixoto, S.V. (Sergio Viana), Peltonen, M. (Markku), Peters, A., Peykari, N. (Niloofar), Pham, S.T. (Son Thai), Pitakaka, F. (Freda), Piwonska, A. (Aleksandra), Piwonski, J. (Jerzy), Plans-Rubió, P. (Pedro), Porta, M., Portegies, M.L.P. (Marileen), Poustchi, H. (Hossein), Pradeepa, R. (Rajendra), Price, J.F. (Jackie F.), Punab, M. (Margus), Qasrawi, R.F. (Radwan F.), Qorbani, M. (Mostafa), Radisauskas, R. (Ricardas), Rahman, M. (Mahmudur), Raitakari, O. (Olli), Rao, S.R. (Sudha Ramachandra), Ramke, J. (Jacqueline), Ramos, R. (Rafel), Rampal, S. (Sanjay), Rathmann, W. (Wolfgang), Redón, J. (Josep), Reganit, P.F.M. (Paul Ferdinand M.), Rigo, F. (Fernando), Robinson, S.M. (Siân), Robitaille, C. (Cynthia), Rodríguez Artalejo, F. (Fernando), Del CristoRodriguez-Perez, M. (María), Rodríguez-Villamizar, L.A. (Laura A.), Rojas-Martinez, R. (Rosalba), Ronkainen, K. (Kimmo), Rosengren, A. (Annika), Rubinstein, A. (Adolfo), Rui, O. (Ornelas), Ruiz-Betancourt, B.S. (Blanca Sandra), Horimoto, A.R.V.R. (Andrea R.V. Russo), Rutkowski, M. (Marcin), Sabanayagam, C. (Charumathi), Sachdev, H.S. (Harshpal S.), Saidi, O. (Olfa), Sakarya, S. (Sibel), Salanave, B. (Benoit), Salonen, J.T. (Jukka T.), Salvetti, M. (Massimo), Sánchez-Abanto, J. (Jose), Santos, D. (Diana), Dos Santos, R.N. (Renata Nunes), Santos, R. (Rute), Saramies, J. (Jouko), Sardinha, L.B. (Luis B.), Sarrafzadegan, N. (Nizal), Saum, K.-U. (Kai-Uwe), Scazufca, M. (Marcia), Schargrodsky, H. (Herman), Scheidt-Nave, C. (C.), Sein, A.A. (Aye Aye), Sharma, S.K. (Sanjb K.), Shaw, J.E., Shibuya, K. (Kenji), Shin, Y. (Youchan), Shiri, R. (Rahman), Siantar, R. (Rosalynn), Sibai, A.M. (Abla M.), Simon, M. (Mary), Simons, J. (Judith), Simons, L.A. (Leon A.), Sjostrom, M. (Michael), Slowikowska-Hilczer, J. (Jolanta), Slusarczyk, P. (Przemyslaw), Smeeth, L. (Liam), Snijder, M.B. (Marieke), So, H.-K. (Hung-Kwan), Sobngwi, E. (Eugène), Söderberg, S. (Stefan), Solfrizzi, V. (Vincenzo), Sonestedt, E. (Emily), Soumare, A. (Aicha), Staessen, J.A. (Jan A.), Stathopoulou, M.G. (Maria G.), Steene-Johannessen, J. (Jostein), Stehle, P. (Peter), Stein, A.D. (Aryeh D.), Stessman, J. (Jochanan), Stöckl, D. (Doris), Stokwiszewski, J. (Jakub), Stronks, K. (Karien), Strufaldi, M.W. (Maria Wany), Sun, C.-A. (Chien-An), Sundstrom, J. (Johan), Sung, Y.-T. (Yn-Tz), Suriyawongpaisal, P. (Paibul), Sy, R.G. (Rody G.), Tai, E.S. (E. Shyong), Tamosiunas, A. (Abdonas), Tang, L. (Line), Tarawneh, M. (Mohammed), Tarqui-Mamani, C.B. (Carolina B), Taylor, A. (Anne), Theobald, H. (Holger), Thijs, L. (Lutgarde), Thuesen, L. (Leif), Tolonen, H.K. (Hanna K.), Tolstrup, J.S. (Janne S.), Topbas, M. (Murat), Torrent, M. (Maties), Traissac, P. (Pierre), Trinh, O.T.H. (Oanh T.H.), Tulloch-Reid, M.K. (Marshall K.), Tuomainen, T.-P. (Tomi-Pekka), Turley, M.L. (Maria L.), Tzourio, C. (Christophe), Ueda, P. (Peter), Ukoli, F.A.M. (Flora A.M.), Ulmer, H. (Hanno), Uusitalo, H.M.T. (Hannu M.T.), Valdivia, G. (Gonzalo), Valvi, D. (Damaskini), Rossem, L. (Lenie) van, Valkengoed, I. (Irene) van, Vanderschueren, D. (Dirk), Vanuzzo, D. (Diego), Vega, T. (Tomas), Velasquez-Melendez, G. (Gustavo), Veronesi, G. (Giovanni), Verschuren, W.M.M. (W.M. Monique), Verstraeten, R. (Roosmarijn), Viet, L. (Lucie), Vioque, J. (Jesus), Virtanen, J.K. (Jyrki K.), Visvikis-Siest, S. (Sophie), Viswanathan, B. (Bharathi), Vollenweider, P. (Peter), Voutilainen, S. (Sari), Vrijheid, M. (Martine), Wade, A.N. (Alisha N.), Wagner, A. (Aline), Walton, J. (Janette), Wan Mohamud, W.N. (Wan Nazaimoon), Wang, F. (Feng), Wang, M.-D. (Ming-Dong), Wang, Q. (Qian), Wang, Y. (Ying), Wannamethee, S.G. (Goya), Weerasekera, D. (Deepa), Whincup, P.H. (Peter), Widhalm, K. (Kurt), Wiecek, A. (Andrzej), Wijga, A.H. (Alet), Wilks, R.J. (Rainford J.), Willeit, J. (Johann), Wilsgaard, T. (Tom), Wojtyniak, B. (Bogdan), Wong, T.Y. (Tien Yin), Woo, J. (Jean), Woodward, M. (Mark), Wu, F.C. (Frederick C.), Wu, S.L. (Shou Ling), Xu, H. (Haiquan), Yan, W. (Weili), Yang, X. (Xiaoguang), Ye, X. (Xingwang), Yoshihara, A. (Akihiro), Younger-Coleman, N.O. (Novie O.), Zambon, S. (Sabina), Zargar, A.H. (Abdul Hamid), Zdrojewski, T. (T.), Zhao, W. (Wenhua), Zheng, Y. (Yingfeng), Cisneros, J.Z. (Julio Zuñiga), Zhou, B. (Bin), Lu, Y. (Yuan), Hajifathalian, K. (Kaveh), Bentham, J. (James), Di Cesare, M. (Mariachiara), Danaei, G. (Goodarz), Bixby, H. (Honor), Cowan, M.J. (Melanie J.), Ali, M.K. (Mohammed), Taddei, C. (Cristina), Lo, W.-C. (Wei-Cheng), Reis-Santos, B. (Barbara), Stevens, G.A. (Gretchen A.), Riley, L.M. (Leanne M.), Miranda, J.J. (J. Jaime), Bjerregaard, P. (Peter), Rivera, J.A. (Juan A.), Fouad, H.M. (Heba M.), Ma, G. (Guansheng), Mbanya, J.C.N. (Jean Claude N.), McGarvey, S.T. (Stephen T.), Mohan, V. (Viswanathan), Onat, A. (Altan), Pilav, A. (Aida), Ramachandran, A. (Ambady), Ben Romdhane, H. (Habiba), Paciorek, C.J. (Christopher J.), Bennett, J.E. (James E.), Ezzati, M. (Majid), Abdeen, Z.A. (Ziad A.), Kadir, K.A. (Khalid Abdul), Abu-Rmeileh, N.M. (Niveen M.), Acosta-Cazares, B. (Benjamin), Adams, R. (Robert), Aekplakorn, W. (Wichai), Aguilar-Salinas, C.A. (Carlos), Agyemang, C.O. (Charles), Ahmadvand, A. (Alireza), Al-Othman, A.R. (Amani Rashed), Alkerwi, A. (Ala'a), Amouyel, P. (Philippe), Amuzu, A. (Antoinette), Bo Andersen, L. (Lars), Anderssen, S.A. (Sigmund A.), Anjana, R.M. (Ranjit Mohan), Aounallah-Skhiri, H. (Hajer), Aris, T. (Tahir), Arlappa, N. (Nimmathota), Arveiler, D. (Dominique), Assah, F.K. (Felix K.), Avdicová, M. (Mária), Azizi, J. (Joshan), Balakrishna, N. (Nagalla), Bandosz, P. (Piotr), Barbagallo, C.M. (Carlo M.), Barceló, A. (Alberto), Batieha, A.M. (Anwar M.), Baur, L.A. (Louise A.), Benet, M. (Mikhail), Bernabe-Ortiz, A. (Antonio), Bharadwaj, S. (Sumit), Bhargava, S.K. (Santosh K.), Bi, Y. (Yufang), Bjertness, E. (Espen), Bjertness, M.B. (Marius B.), Björkelund, C. (Cecilia), Blokstra, A. (Anneke), Bo, S. (Simona), Boehm, B.O. (Bernhard), Boissonnet, C.P. (Carlos P.), Bovet, P. (Pascal), Brajkovich, I. (Imperia), Breckenkamp, J. (Juergen), Brenner, H. (Hermann), Brewster, L.M. (Lizzy), Brian, G.R. (Garry R.), Bruno, G. (Graziella), Bugge, A. (Anna), De León, A.C. (Antonio Cabrera), Can, G. (Günay), Cåndido, A.P.C. (Ana Paula C.), Capuano, V. (Vincenzo), Carlsson, A.C. (Axel C.), Carvalho, M.J. (Maria J.), Casanueva, F.F. (Felipe F.), Casas, J.P. (Juan Pablo), Caserta, C.A. (Carmelo A.), Castetbon, K., Chamukuttan, S. (Snehalatha), Chaturvedi, N. (Nishi), Chen, C.-J. (Chien-Jen), Chen, F. (Fangfang), Chen, S. (Shuohua), Cheng, C.-Y. (Ching-Yu), Chetrit, A. (Angela), Chiou, S.-T. (Shu-Ti), Cho, Y. (Yumi), Chudek, J. (Jerzy), Cifkova, R. (Renata), Claessens, F., Concin, H. (Hans), Cooper, C. (Charles), Cooper, R. (Rachel), Costanzo, S. (Simona), Cottel, D. (Dominique), Cowell, C. (Chris), Crujeiras, A.B. (Ana B.), D'Arrigo, G. (Graziella), Dallongeville, J., Dankner, R. (Rachel), Dauchet, L. (Luc), De Gaetano, G. (Giovanni), De Henauw, S. (Stefaan), Deepa, M. (Mohan), Dehghan, A. (Abbas), Deschamps, V. (Valerie), Dhana, K. (Klodian), Di Castelnuovo, A.F. (Augusto F.), Djalalinia, S. (Shirin), Doua, K. (Kouamelan), Drygas, W. (Wojciech), Du, Y. (Yong), Dzerve, V. (Vilnis), Egbagbe, E.E. (Eruke E.), Eggertsen, R. (Robert), El Ati, J. (Jalila), Elosua, R. (Roberto), Erasmus, R.T. (Rajiv T.), Erem, C. (Cihangir), Ergor, G. (Gul), Eriksen, L. (Louise), Escobedo-De La Peña, J. (Jorge), Fall, C.H. (Caroline H.), Farzadfar, F. (Farshad), Felix-Redondo, F.J. (Francisco J.), Ferguson, T.S. (Trevor S.), Fernández-Bergés, D. (Daniel), Ferrari, M. (Marika), Ferreccio, C. (Catterina), Feskens, E.J.M. (Edith), Finn, J.D. (Joseph D.), Föger, B. (Bernhard), Foo, L.H. (Leng Huat), Forslund, A.-S. (Ann-Sofie), Francis, D.K. (Damian K.), Do Carmo Franco, M. (Maria), Franco, O.H. (Oscar), Frontera, G. (Guillermo), Furusawa, T. (Takuro), Gaciong, Z. (Zbigniew), Garnett, S.P. (Sarah P.), Gaspoz, J.-M. (Jean-Michel), Gasull, M. (Magda), Gates, L. (Louise), Geleijnse, J.M. (Marianne), Ghasemian, A. (Anoosheh), Ghimire, A. (Anup), Giampaoli, S. (Simona), Gianfagna, F. (Francesco), Giovannelli, J. (Jonathan), Giwercman, A. (Aleksander), Gross, M., Rivas, J.P.G. (Juan P. González), Gorbea, M.B. (Mariano Bonet), Gottrand, F. (Frederic), Grafnetter, D. (Dušan), Grodzicki, T. (Tomasz), Grøntved, A. (Anders), Gruden, G. (Grabriella), Gu, D. (Dongfeng), Guan, O.P. (Ong Peng), Guerrero, R. (Ramiro), Guessous, I. (Idris), Guimaraes, A.L. (Andre L.), Gutierrez, L. (Laura), Hambleton, I.R. (Ian R.), Hardy, R., Kumar, R.H. (Rachakulla Hari), Hata, J. (Jun), He, J. (Jiang), Heidemann, C. (Christin), Herrala, S. (Sauli), Hihtaniemi, I.T. (Ilpo Tapani), Ho, S.Y. (Sai Yin), Ho, S.C. (Suzanne C.), Hofman, A. (Albert), Hormiga, C.M. (Claudia M.), Horta, B.L. (Bernardo L.), Houti, L. (Leila), Howitt, C. (Christina), Htay, T.T. (Thein Thein), Htet, A.S. (Aung Soe), Htike, M.M.T. (Maung Maung Than), Hu, Y. (Yang), Hussieni, A.S. (Abdullatif S.), Huybrechts, I. (Inge), Hwalla, N. (Nahla), Iacoviello, L. (Licia), Iannone, A.G. (Anna G.), Ibrahim, M.M. (M. Mohsen), Ikeda, N. (Nayu), Ikram, M.A. (M. Arfan), Irazola, V. (Vilma), Islam, M. (Muhammad), Iwasaki, M. (Masanori), Jacobs, J.M. (Jeremy M.), Jafar, T.H. (Tazeen), Jamil, K.M. (Kazi M.), Jasienska, G. (Grazyna), Jiang, C.Q. (Chao Qiang), Jonas, J.B., Joshi, P. (Pradeep), Kafatos, A. (Anthony), Kalter-Leibovici, O. (Ofra), Kasaeian, A. (Amir), Katz, J. (Joanne), Kaur, P. (Prabhdeep), Kavousi, M. (Maryam), Keinanen-Kiukaanniemi, S. (Sirkka), Kelishadi, R. (Roya), Kengne, A.P. (Andre Pascal), Kersting, M. (Mathilde), Khader, Y.S. (Yousef Saleh), Khalili, D. (Davood), Khang, Y.-H. (Young-Ho), Kiechl, S. (Stefan), Kim, J. (Jeongseon), Kolsteren, P. (Patrick), Korrovits, P. (Paul), Kratzer, W. (Wolfgang), Kromhout, D. (Daan), Kujala, U.M. (Urho), Kula, K. (Krzysztof), Kyobutungi, C. (Catherine), Laatikainen, T. (Tiina), Lachat, C. (Carl), Laid, Y. (Youcef), Lam, T.H. (Tai Hing), Landrove, O. (Orlando), Lanska, V. (Vera), Lappas, G. (Georg), Laxmaiah, A. (Avula), Leclercq, C. (Catherine), Lee, J. (Jeannette), Lee, J. (Jeonghee), Lehtimäki, T. (Terho), Lekhraj, R. (Rampal), León-Muñoz, L.M. (Luz M.), Li, Y. (Yanping), Lim, W.-Y. (Wei-Yen), Lima-Costa, M.F. (M. Fernanda), Lin, H.-H. (Hsien-Ho), Lin, X. (Xu), Lissner, L. (Lauren), Lorbeer, R. (Roberto), Lozano, J.E. (José Eugenio), Luksiene, D. (Dalia), Lundqvist, A. (Annamari), Lytsy, P. (Per), Machado-Coelho, G.L.L. (George L.L.), Machi, S. (Suka), Maggi, S. (Stefania), Magliano, D.J., Makdisse, M. (Marcia), Rao, K.M. (Kodavanti Mallikharjuna), Manios, Y., Manzato, E. (Enzo), Margozzini, P. (Paula), Marques-Vidal, P. (Pedro), Martorell, R. (Reynaldo), Masoodi, S.R. (Shariq R.), Mathiesen, E.B. (Ellisiv), Matsha, T.E. (Tandi E.), McFarlane, S.R. (Shelly R.), McLachlan, S. (Stela), McNulty, B.A. (Breige A.), Mediene-Benchekor, S. (Sounnia), Meirhaeghe, A. (Aline), Menezes, A.M.B. (Ana Maria B.), Merat, S. (Shahin), Meshram, I.I. (Indrapal I.), Mi, J. (Jie), Miquel, J.F. (Juan Francisco), Mohamed, M.K. (Mostafa K.), Mohammad, K. (Kazem), Mohammadifard, N. (Noushin), Mohd Yusoff, M.F. (Muhammad Fadhli), Møller, N.C. (Niels C.), Molnár, D. (Dénes), Mondo, C.K. (Charles K.), Morejon, A. (Alain), Moreno, L.A. (Luis A.), Morgan, K. (Karen), Moschonis, G., Mossakowska, M. (Malgorzata), Mostafa, A. (Aya), Mota, J. (Jorge), Motta, J. (Jorge), Mu, T.T. (Thet Thet), Muiesan, M.L. (Maria Lorenza), Müller-Nurasyid, M. (Martina), Mursu, J. (Jaakko), Nagel, G. (Gabriele), Námešná, J. (Jana), Nang, E.E.K. (Ei Ei K.), Nangia, M. (Monika), Navarrete-Muñoz, E.M., Ndiaye, N.C. (Ndeye Coumba), Nenko, I. (Ilona), Nervi, F. (Flavio), Nguyen, N.D. (Nguyen D.), Nguyen, Q.N. (Quang Ngoc), Nieto-Martínez, R.E. (Ramfis E.), Ning, G. (Guang), Ninomiya, T. (Toshiharu), Noale, M. (Marianna), Noto, D. (Davide), Al Nsour, M. (Mohannad), Ochoa-Avilés, A.M. (Angélica M.), Oh, K. (Kyungwon), Ordunez, P. (Pedro), Osmond, C. (Clive), Otero, J.A. (Johanna A.), Owusu-Dabo, E. (Ellis), Pahomova, E. (Elena), Palmieri, L. (Luigi), Panda-Jonas, S. (Songhomitra), Panza, F. (Francesco), Parsaeian, M. (Mahboubeh), Peixoto, S.V. (Sergio Viana), Peltonen, M. (Markku), Peters, A., Peykari, N. (Niloofar), Pham, S.T. (Son Thai), Pitakaka, F. (Freda), Piwonska, A. (Aleksandra), Piwonski, J. (Jerzy), Plans-Rubió, P. (Pedro), Porta, M., Portegies, M.L.P. (Marileen), Poustchi, H. (Hossein), Pradeepa, R. (Rajendra), Price, J.F. (Jackie F.), Punab, M. (Margus), Qasrawi, R.F. (Radwan F.), Qorbani, M. (Mostafa), Radisauskas, R. (Ricardas), Rahman, M. (Mahmudur), Raitakari, O. (Olli), Rao, S.R. (Sudha Ramachandra), Ramke, J. (Jacqueline), Ramos, R. (Rafel), Rampal, S. (Sanjay), Rathmann, W. (Wolfgang), Redón, J. (Josep), Reganit, P.F.M. (Paul Ferdinand M.), Rigo, F. (Fernando), Robinson, S.M. (Siân), Robitaille, C. (Cynthia), Rodríguez Artalejo, F. (Fernando), Del CristoRodriguez-Perez, M. (María), Rodríguez-Villamizar, L.A. (Laura A.), Rojas-Martinez, R. (Rosalba), Ronkainen, K. (Kimmo), Rosengren, A. (Annika), Rubinstein, A. (Adolfo), Rui, O. (Ornelas), Ruiz-Betancourt, B.S. (Blanca Sandra), Horimoto, A.R.V.R. (Andrea R.V. Russo), Rutkowski, M. (Marcin), Sabanayagam, C. (Charumathi), Sachdev, H.S. (Harshpal S.), Saidi, O. (Olfa), Sakarya, S. (Sibel), Salanave, B. (Benoit), Salonen, J.T. (Jukka T.), Salvetti, M. (Massimo), Sánchez-Abanto, J. (Jose), Santos, D. (Diana), Dos Santos, R.N. (Renata Nunes), Santos, R. (Rute), Saramies, J. (Jouko), Sardinha, L.B. (Luis B.), Sarrafzadegan, N. (Nizal), Saum, K.-U. (Kai-Uwe), Scazufca, M. (Marcia), Schargrodsky, H. (Herman), Scheidt-Nave, C. (C.), Sein, A.A. (Aye Aye), Sharma, S.K. (Sanjb K.), Shaw, J.E., Shibuya, K. (Kenji), Shin, Y. (Youchan), Shiri, R. (Rahman), Siantar, R. (Rosalynn), Sibai, A.M. (Abla M.), Simon, M. (Mary), Simons, J. (Judith), Simons, L.A. (Leon A.), Sjostrom, M. (Michael), Slowikowska-Hilczer, J. (Jolanta), Slusarczyk, P. (Przemyslaw), Smeeth, L. (Liam), Snijder, M.B. (Marieke), So, H.-K. (Hung-Kwan), Sobngwi, E. (Eugène), Söderberg, S. (Stefan), Solfrizzi, V. (Vincenzo), Sonestedt, E. (Emily), Soumare, A. (Aicha), Staessen, J.A. (Jan A.), Stathopoulou, M.G. (Maria G.), Steene-Johannessen, J. (Jostein), Stehle, P. (Peter), Stein, A.D. (Aryeh D.), Stessman, J. (Jochanan), Stöckl, D. (Doris), Stokwiszewski, J. (Jakub), Stronks, K. (Karien), Strufaldi, M.W. (Maria Wany), Sun, C.-A. (Chien-An), Sundstrom, J. (Johan), Sung, Y.-T. (Yn-Tz), Suriyawongpaisal, P. (Paibul), Sy, R.G. (Rody G.), Tai, E.S. (E. Shyong), Tamosiunas, A. (Abdonas), Tang, L. (Line), Tarawneh, M. (Mohammed), Tarqui-Mamani, C.B. (Carolina B), Taylor, A. (Anne), Theobald, H. (Holger), Thijs, L. (Lutgarde), Thuesen, L. (Leif), Tolonen, H.K. (Hanna K.), Tolstrup, J.S. (Janne S.), Topbas, M. (Murat), Torrent, M. (Maties), Traissac, P. (Pierre), Trinh, O.T.H. (Oanh T.H.), Tulloch-Reid, M.K. (Marshall K.), Tuomainen, T.-P. (Tomi-Pekka), Turley, M.L. (Maria L.), Tzourio, C. (Christophe), Ueda, P. (Peter), Ukoli, F.A.M. (Flora A.M.), Ulmer, H. (Hanno), Uusitalo, H.M.T. (Hannu M.T.), Valdivia, G. (Gonzalo), Valvi, D. (Damaskini), Rossem, L. (Lenie) van, Valkengoed, I. (Irene) van, Vanderschueren, D. (Dirk), Vanuzzo, D. (Diego), Vega, T. (Tomas), Velasquez-Melendez, G. (Gustavo), Veronesi, G. (Giovanni), Verschuren, W.M.M. (W.M. Monique), Verstraeten, R. (Roosmarijn), Viet, L. (Lucie), Vioque, J. (Jesus), Virtanen, J.K. (Jyrki K.), Visvikis-Siest, S. (Sophie), Viswanathan, B. (Bharathi), Vollenweider, P. (Peter), Voutilainen, S. (Sari), Vrijheid, M. (Martine), Wade, A.N. (Alisha N.), Wagner, A. (Aline), Walton, J. (Janette), Wan Mohamud, W.N. (Wan Nazaimoon), Wang, F. (Feng), Wang, M.-D. (Ming-Dong), Wang, Q. (Qian), Wang, Y. (Ying), Wannamethee, S.G. (Goya), Weerasekera, D. (Deepa), Whincup, P.H. (Peter), Widhalm, K. (Kurt), Wiecek, A. (Andrzej), Wijga, A.H. (Alet), Wilks, R.J. (Rainford J.), Willeit, J. (Johann), Wilsgaard, T. (Tom), Wojtyniak, B. (Bogdan), Wong, T.Y. (Tien Yin), Woo, J. (Jean), Woodward, M. (Mark), Wu, F.C. (Frederick C.), Wu, S.L. (Shou Ling), Xu, H. (Haiquan), Yan, W. (Weili), Yang, X. (Xiaoguang), Ye, X. (Xingwang), Yoshihara, A. (Akihiro), Younger-Coleman, N.O. (Novie O.), Zambon, S. (Sabina), Zargar, A.H. (Abdul Hamid), Zdrojewski, T. (T.), Zhao, W. (Wenhua), Zheng, Y. (Yingfeng), and Cisneros, J.Z. (Julio Zuñiga)
Abstract: Background: One of the global targets for non-communicable diseases is to halt, by 2025, the rise in the age standardised adult prevalence of diabetes at its 2010 levels. We aimed to estimate worldwide trends in diabetes, how likely it is for countries to achieve the global target, and how changes in prevalence, together with population growth and ageing, are aff ecting the number of adults with diabetes. Methods: We pooled data from population-based studies that had collected data on diabetes through measurement of its biomarkers. We used a Bayesian hierarchical model to estimate trends in diabetes prevalence-defined as fasting plasma glucose of 7.0 mmol/L or higher, or history of diagnosis with diabetes, or use of insulin or oral hypoglycaemic drugs-in 200 countries and territories in 21 regions, by sex and from 1980 to 2014. We also calculated the posterior probability of meeting the global diabetes target if post-2000 trends continue. Findings: We used data from 751 studies including 4372000 adults from 146 of the 200 countries we make estimates for. Global age-standardised diabetes prevalence increased from 4.3% (95% credible interval 2.4-17.0) in 1980 to 9.0% (7.2-11.1) in 2014 in
Published: 2016
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13. A century of trends in adult human height

Author: Bentham, J. (James), Di Cesare, M. (Mariachiara), Stevens, G.A. (Gretchen A.), Zhou, B. (Bin), Bixby, H. (Honor), Cowan, M. (Melanie), Fortunato, L. (Léa), Bennett, J.E. (James E.), Danaei, G. (Goodarz), Hajifathalian, K. (Kaveh), Lu, Y. (Yuan), Riley, L.M. (Leanne M.), Laxmaiah, A. (Avula), Kontis, V. (Vasilis), Paciorek, C.J. (Christopher J.), Ezzati, M. (Majid), Abdeen, Z.A. (Ziad A.), Hamid, Z.A. (Zargar Abdul), Abu-Rmeileh, N.M. (Niveen M.), Acosta-Cazares, B. (Benjamin), Adams, R. (Robert), Aekplakorn, W. (Wichai), Aguilar-Salinas, C.A. (Carlos), Agyemang, C.O. (Charles), Ahmadvand, A. (Alireza), Ahrens, W. (W.), Al-Hazzaa, H.M. (Hazzaa M.), Al-Othman, A.R. (Amani Rashed), Raddadi, R.A. (Rajaa Al), Ali, M.M. (Mohamed M.), Alkerwi, A. (Ala’a), Alvarez-Pedrerol, M. (Mar), Aly, E. (Eman), Amouyel, P. (Philippe), Amuzu, A. (Antoinette), Andersen, L.B. (Lars Bo), Anderssen, S.A. (Sigmund A.), Anjana, R.M. (Ranjit Mohan), Aounallah-Skhiri, H. (Hajer), Ariansen, I. (Inger), Aris, T. (Tahir), Arlappa, N. (Nimmathota), Arveiler, D. (Dominique), Assah, F.K. (Felix K.), Avdicová, M. (Mária), Azizi, J. (Joshan), Babu, B.V. (Bontha V.), Bahijri, S. (Suhad), Balakrishna, N. (Nagalla), Bandosz, P. (Piotr), Banegas, J.R. (José R.), Barbagallo, C.M. (Carlo M.), Barceló, A. (Alberto), Barkat, A. (Amina), Barros, M.V. (Mauro V.), Bata, I. (Iqbal), Batieha, A.M. (Anwar M.), Batista, R.L. (Rosangela L.), Baur, L.A. (Louise A.), Beaglehole, R. (Robert), Romdhane, H.B. (Habiba Ben), Benet, M. (Mikhail), Bernabe-Ortiz, A. (Antonio), Bernotiene, G. (Gailute), Bettiol, H. (Heloisa), Bhagyalaxmi, A. (Aroor), Bharadwaj, S. (Sumit), Bhargava, S.K. (Santosh K.), Bhatti, Z. (Zaid), Bhutta, Z.A. (Zulfiqar A), Bi, H. (Hongsheng), Bi, Y. (Yufang), Bjerregaard, P. (Peter), Bjertness, E. (Espen), Bjertness, M.B. (Marius B.), Björkelund, C. (Cecilia), Blokstra, A. (Anneke), Bo, S. (Simona), Bobak, M. (Martin), Boddy, L.M. (Lynne M.), Boehm, B.O. (Bernhard), Boeing, H. (Heiner), Boissonnet, C.P. (Carlos P.), Bongard, V. (Vanina), Bovet, P. (Pascal), Braeckman, L. (Lutgart), Bragt, M.C.E. (Marjolijn C. E.), Brajkovich, I. (Imperia), Branca, F. (Francesco), Breckenkamp, J. (Juergen), Brenner, H. (Hermann), Brewster, L.M. (Lizzy), Brian, G.R. (Garry R.), Bruno, G. (Graziella), Bueno-de-Mesquita, H.B. (H. Bas), Bugge, A. (Anna), Burns, C. (Con), De León, A.C. (Antonio Cabrera), Cacciottolo, J. (Joseph), Cama, T. (Tilema), Cameron, C. (Christine), Camolas, J. (José), Can, G. (Günay), Cândido, A.P.C. (Ana Paula C.), Capuano, V. (Vincenzo), Cardoso, V.C. (Viviane C.), Carlsson, A.C. (Axel C.), Carvalho, M.J. (Maria J.), Casanueva, F.F. (Felipe F.), Casas, J.P. (Juan Pablo), Caserta, C.A. (Carmelo A.), Chamukuttan, S. (Snehalatha), Chan, A.W.M. (Angelique), Chan, Q. (Queenie), Chaturvedi, H.K. (Himanshu K.), Chaturvedi, N. (Nishi), Chen, C.-J. (Chien-Jen), Chen, F. (Fangfang), Chen, H. (Huashuai), Chen, S. (Shuohua), Chen, Z. (Zhengming), Cheng, C.-Y. (Ching-Yu), Chetrit, A. (Angela), Chiolero, A. (Arnaud), Chiou, S.-T. (Shu-Ti), Chirita-Emandi, A. (Adela), Cho, B. (Belong), Cho, Y. (Yumi), Christensen, K. (Kaare), Chudek, J. (Jerzy), Cifkova, R. (Renata), Claessens, F., Clays, E. (Els), Concin, H. (Hans), Cooper, C. (Charles), Cooper, R. (Rachel), Coppinger, T.C. (Tara C.), Costanzo, S. (Simona), Cottel, D. (Dominique), Cowell, C. (Chris), Craig, C.L. (Cora L.), Crujeiras, A.B. (Ana B.), D’Arrigo, G. (Graziella), d’Orsi, E. (Eleonora), Dallongeville, J., Damasceno, A. (Albertino), Damsgaard, C.T. (Camilla T.), Dankner, R. (Rachel), Dauchet, L. (Luc), De Backer, G. (Guy), De Bacquer, D. (Dirk), de Gaetano, G. (Giovanni), De Henauw, S. (Stefaan), De Smedt, D. (Delphine), Deepa, M. (Mohan), Deev, A.D. (Alexander D.), Dehghan, A. (Abbas), Delisle, H. (Hélène), Delpeuch, F. (Francis), Deschamps, V. (Valérie), Dhana, K. (Klodian), Di Castelnuovo, A.F. (Augusto F.), Dias-da-Costa, J.S. (Juvenal Soares), Diaz, A. (Alejandro), Djalalinia, S. (Shirin), Do, H.T.P. (Ha T. P.), Dobson, A.J. (Annette J.), Donfrancesco, C. (Chiara), Donoso, S.P. (Silvana P.), Döring, A. (Angela), Doua, K. (Kouamelan), Drygas, W. (Wojciech), Dzerve, V. (Vilnis), Egbagbe, E.E. (Eruke E.), Eggertsen, R. (Robert), Ekelund, U. (Ulf), El Ati, J. (Jalila), Elliott, P. (Paul), Engle-Stone, R. (Reina), Erasmus, R.T. (Rajiv T.), Erem, C. (Cihangir), Eriksen, L. (Louise), Escobedo-de la Peña, J. (Jorge), Evans, A. (Alun), Faeh, D. (David), Fall, C.H. (Caroline H.), Farzadfar, F. (Farshad), Felix-Redondo, F.J. (Francisco J.), Ferguson, T.S. (Trevor S.), Fernández-Bergés, D. (Daniel), Ferrante, D. (Daniel), Ferrari, M. (Marika), Ferreccio, C. (Catterina), Ferrieres, J. (Jean), Finn, J.D. (Joseph D.), Fischer, K. (Krista), Flores, E.M. (Eric Monterubio), Föger, B. (Bernhard), Foo, L.H. (Leng Huat), Forslund, A.-S. (Ann-Sofie), Forsner, M. (Maria), Fortmann, S.P. (Stephen), Fouad, H.M. (Heba M.), Francis, D.K. (Damian K.), Do Carmo Franco, M. (Maria), Franco, O.H. (Oscar), Frontera, G. (Guillermo), Fuchs, F.D. (Flavio D.), Fuchs, S.C. (Sandra C.), Fujita, Y. (Yuki), Furusawa, T. (Takuro), Gaciong, Z. (Zbigniew), Gafencu, M. (Mihai), Gareta, D. (Dickman), Garnett, S.P. (Sarah P.), Gaspoz, J.-M. (Jean-Michel), Gasull, M. (Magda), Gates, L. (Louise), Geleijnse, J.M. (Marianne), Ghasemian, A. (Anoosheh), Giampaoli, S. (Simona), Gianfagna, F. (Francesco), Giovannelli, J. (Jonathan), Giwercman, A. (Aleksander), Goldsmith, R.A. (Rebecca A.), Gonçalves, H. (Helen), Gross, M., González Rivas, J.P. (Juan P.), Gorbea, M.B. (Mariano Bonet), Gottrand, F. (Frederic), Graff-Iversen, S. (Sidsel), Grafnetter, D. (Dušan), Grajda, A. (Aneta), Grammatikopoulou, M.G. (Maria G.), Gregor, R.D. (Ronald D.), Grodzicki, T. (Tomasz), Grøntved, A. (Anders), Gruden, G. (Grabriella), Grujic, V. (Vera), Gu, D. (Dongfeng), Gualdi-Russo, E. (Emanuela), Guan, O.P. (Ong Peng), Gudnason, V. (Vilmundur), Guerrero, R. (Ramiro), Guessous, I. (Idris), Guimaraes, A.L. (Andre L.), Gulliford, M.C. (Martin C.), Gunnlaugsdottir, J. (Johanna), Gunter, M. (Marc), Guo, X. (Xiuhua), Guo, Y. (Yin), Gupta, P.C. (Prakash C.), Gureje, O. (Oye), Gurzkowska, B. (Beata), Gutierrez, L. (Laura), Gutzwiller, F. (Felix), Halkjær, J., Hambleton, I.R. (Ian R.), Hardy, R., Kumar, R.H. (Rachakulla Hari), Hata, J. (Jun), Hayes, A.J. (Alison J.), He, J. (Jiang), Hendriks, M.E. (Marleen), Cadena, L.H. (Leticia Hernandez), Herrala, S. (Sauli), Heshmat, R. (Ramin), Hihtaniemi, I.T. (Ilpo Tapani), Ho, S.Y. (Sai Yin), Ho, S.C. (Suzanne C.), Hobbs, M. (Michael), Hofman, A. (Albert), Hormiga, C.M. (Claudia M.), Horta, B.L. (Bernardo L.), Houti, L. (Leila), Howitt, C. (Christina), Htay, T.T. (Thein Thein), Htet, A.S. (Aung Soe), Htike, M.M.T. (Maung Maung Than), Hu, Y. (Yonghua), Husseini, A. (Abdullatif), Huu, C.N. (Chinh Nguyen), Huybrechts, I. (Inge), Hwalla, N. (Nahla), Iacoviello, L. (Licia), Iannone, A.G. (Anna G.), Ibrahim, M.M. (Mohsen M.), Ikeda, N. (Nayu), Ikram, M.A. (Arfan), Irazola, V. (Vilma), Islam, M. (Muhammad), Ivkovic, V. (Vanja), Iwasaki, M. (Masanori), Jackson, R.T. (Rod T.), Jacobs, J.M. (Jeremy M.), Jafar, T.H. (Tazeen), Jamil, K.M. (Kazi M.), Jamrozik, K., Janszky, I. (Imre), Jasienska, G. (Grazyna), Jelakovic, B. (Bojan), Jiang, C.Q. (Chao Qiang), Joffres, M. (Michel), Johansson, M. (Mattias), Jonas, J.B. (Jost B.), Jorgensen, T. (Torben), Joshi, P. (Pradeep), Juolevi, A. (Anne), Jurak, G. (Gregor), Jureša, V. (Vesna), Kaaks, R. (Rudolf), Kafatos, A. (Anthony), Kalter-Leibovici, O. (Ofra), Kapantais, E. (Efthymios), Kasaeian, A. (Amir), Katz, J. (Joanne), Kaur, P. (Prabhdeep), Kavousi, M. (Maryam), Keil, M. (Mark), Boker, L.K. (Lital Keinan), Keinanen-Kiukaanniemi, S. (Sirkka), Kelishadi, R. (Roya), Kemper, H.C.G., Kengne, A.P. (Andre Pascal), Kersting, M. (Mathilde), Key, T. (Tim), Khader, Y.S. (Yousef Saleh), Khalili, D. (Davood), Khang, Y.-H. (Young-Ho), Khaw, K.-T. (Kay-Tee), Khouw, I.M.S.L. (Ilse M. S. L.), Kiechl, S. (Stefan), Killewo, J. (Japhet), Kim, J. (Jeongseon), Klimont, J. (Jeannette), Klumbiene, J. (Jurate), Koirala, B. (Bhawesh), Kolle, E. (Elin), Kolsteren, P. (Patrick), Korrovits, P. (Paul), Koskinen, S. (Seppo), Kouda, K. (Katsuyasu), Koziel, S. (Slawomir), Kratzer, W. (Wolfgang), Krokstad, S. (Steinar), Kromhout, D. (Daan), Kruger, H.S. (Herculina S.), Kubinova, R., Kujala, U.M. (Urho), Kula, K. (Krzysztof), Kulaga, Z. (Zbigniew), Krishna Kumar, R., Kurjata, P. (Pawel), Kusuma, Y.S. (Yadlapalli S.), Kuulasmaa, K. (Kari), Kyobutungi, C. (Catherine), Laamiri, F.Z. (Fatima Zahra), Laatikainen, T. (Tiina), Lachat, C. (Carl), Laid, Y. (Youcef), Lam, T.H. (Tai Hing), Landrove, O. (Orlando), Lanska, V. (Vera), Lappas, G. (Georg), Larijani, B. (Bagher), Laugsand, L.E. (Lars E.), Bao, K.L.N. (Khanh Le Nguyen), Le, T.D. (Tuyen D.), Leclercq, C. (Catherine), Lee, J.J.M. (Jeannette), Lee, J. (Jeonghee), Lehtimäki, T. (Terho), Lekhraj, R. (Rampal), León-Muñoz, L.M. (Luz M.), Li, Y. (Yanping), Lilly, C.L. (Christa L.), Lim, W.-Y. (Wei-Yen), Fernanda Lima-Costa, M., Lin, H.-H. (Hsien-Ho), Lin, X. (Xu), Linneberg, A. (Allan), Lissner, L. (Lauren), Litwin, M. (Mieczyslaw), Liu, J. (Jing), Lorbeer, R. (Roberto), Lotufo, P.A. (Paulo A), Lozano, J.E. (José Eugenio), Luksiene, D. (Dalia), Lundqvist, A. (Annamari), Lunet, N. (Nuno), Lytsy, P. (Per), Ma, G. (Guansheng), Ma, J. (Jun), Machado-Coelho, G.L.L. (George L. L.), Machi, S. (Suka), Maggi, S. (Stefania), Magliano, D.J., Maire, B. (Bernard), Makdisse, M. (Marcia), Malekzadeh, R. (Reza), Malhotra, R. (Rahul), Rao, K.M. (Kodavanti Mallikharjuna), Malyutina, S., Manios, Y., Mann, J.I. (Jim I.), Manzato, E. (Enzo), Margozzini, P. (Paula), Markey, O. (Oonagh), Marques-Vidal, P. (Pedro), Marrugat, J. (Jaume), Martin-Prevel, Y. (Yves), Martorell, R. (Reynaldo), Masoodi, S.R. (Shariq R.), Mathiesen, E.B. (Ellisiv), Matsha, T.E. (Tandi E.), Mazur, A. (Artur), Mbanya, J.C.N. (Jean Claude N.), McFarlane, S.R. (Shelly R.), McGarvey, S.T. (Stephen T.), McKee, M. (Martin), McLachlan, S. (Stela), McLean, R.M. (Rachael M.), McNulty, B.A. (Breige A.), Yusof, S.M. (Safiah Md), Mediene-Benchekor, S. (Sounnia), Meirhaeghe, A. (Aline), Meisinger, C. (Christa), Menezes, A.M.B. (Ana Maria B.), Mensink, G.B.M. (Gert B. M.), Meshram, I.I. (Indrapal I.), Metspalu, A. (Andres), Mi, J. (Jie), Michaelsen, K.F., Mikkel, K. (Kairit), Miller, J.C. (Jody C.), Miquel, J.F. (Juan Francisco), Jaime Miranda, J., Mišigoj-Durakovic, M. (Marjeta), Mohamed, M.K. (Mostafa K.), Mohammad, K. (Kazem), Mohammadifard, N. (Noushin), Mohan, V. (Viswanathan), Yusoff, M.F.M. (Muhammad Fadhli Mohd), Molbo, D. (Drude), Møller, N.C. (Niels C.), Molnár, D. (Dénes), Mondo, C.K. (Charles K.), Monterrubio, E.A. (Eric A.), Monyeki, K.D.K. (Kotsedi Daniel K.), Moreira, L.B. (Leila B.), Morejon, A. (Alain), Moreno, L.A. (Luis A.), Morgan, K. (Karen), Mortensen, E.L. (Erik Lykke), Moschonis, G., Mossakowska, M. (Malgorzata), Mostafa, A. (Aya), Mota, J. (Jorge), Motlagh, M.E. (Mohammad Esmaeel), Motta, J. (Jorge), Mu, T.T. (Thet Thet), Muiesan, M.L. (Maria Lorenza), Müller-Nurasyid, M. (Martina), Murphy, N. (Neil), Mursu, J. (Jaakko), Murtagh, E.M. (Elaine M.), Musa, K.I. (Kamarul Imran), Musil, V. (Vera), Nagel, G. (Gabriele), Nakamura, H. (Harunobu), Námešná, J. (Jana), Nang, E.E.K. (Ei Ei K.), Nangia, M. (Monika), Nankap, M. (Martin), Narake, S. (Sameer), Navarrete-Muñoz, E.M., Neal, W.A. (William A.), Nenko, I. (Ilona), Neovius, M. (Martin), Nervi, F. (Flavio), Neuhauser, H.K. (Hannelore K.), Nguyen, N.D. (Nguyen D.), Nguyen, Q.N. (Quang Ngoc), Nieto-Martínez, R.E. (Ramfis E.), Ning, G. (Guang), Ninomiya, T. (Toshiharu), Nishtar, S. (Sania), Noale, M. (Marianna), Norat, T. (Teresa), Noto, D. (Davide), Nsour, M.A. (Mohannad Al), O’Reilly, D. (Dermot), Oh, K. (Kyungwon), Olayan, I.H. (Iman H.), Olinto, M.T.A. (Maria Teresa Anselmo), Oltarzewski, M. (Maciej), Omar, M.A. (Mohd A.), Onat, A. (Altan), Ordunez, P. (Pedro), Ortiz, A.P. (Ana P.), Osler, M. (Merete), Osmond, C. (Clive), Ostojic, S.M. (Sergej M.), Otero, J.A. (Johanna A.), Overvad, K. (Kim), Owusu-Dabo, E. (Ellis), Paccaud, F.M. (Fred Michel), Padez, C. (Cristina), Pahomova, E. (Elena), Pajak, A. (Andrzej), Palli, D. (Domenico), Palloni, A. (Alberto), Palmieri, L. (Luigi), Panda-Jonas, S. (Songhomitra), Panza, F. (Francesco), Parnell, W.R. (Winsome R.), Parsaeian, M. (Mahboubeh), Pecin, I. (Ivan), Pednekar, M.S. (Mangesh S.), Peeters, P.H.M., Peixoto, S.V. (Sergio Viana), Peltonen, M. (Markku), Pereira, A. (A.), Pérez, C.M. (Cynthia M.), Peters, A., Petkeviciene, J. (Janina), Peykari, N. (Niloofar), Pham, S.T. (Son Thai), Pigeot, I. (Iris), Pikhart, H. (Hynek), Pilav, A. (Aida), Pilotto, A. (Alberto), Pistelli, F. (Francesco), Pitakaka, F. (Freda), Piwonska, A. (Aleksandra), Plans-Rubió, P. (Pedro), Poh, B.K. (Bee Koon), Porta, M., Portegies, M.L.P. (Marileen), Poulimeneas, D. (Dimitrios), Pradeepa, R. (Rajendra), Prashant, M. (Mathur), Price, J.F. (Jackie F.), Puiu, M. (Maria), Punab, M. (Margus), Qasrawi, R.F. (Radwan F.), Qorbani, M. (Mostafa), Bao, T.Q. (Tran Quoc), Radic, I. (Ivana), Radisauskas, R. (Ricardas), Rahman, M.-M. (Mah-mudur), Raitakari, O. (Olli), Raj, M. (Manu), Rao, S.R. (Sudha Ramachandra), Ramachandran, A. (Ambady), Ramke, J. (Jacqueline), Ramos, R. (Rafel), Rampal, S. (Sanjay), Rasmussen, F. (Finn), Redón, J. (Josep), Reganit, P.F.M. (Paul Ferdinand M.), Ribeiro, R. (Robespierre), Riboli, E. (Elio), Rigo, F. (Fernando), Rinke de Wit, T.F. (Tobias), Ritti-Dias, R.M. (Raphael M.), Rivera, J.A. (Juan A.), Robinson, S.M. (Siân), Robitaille, C. (Cynthia), Rodríguez Artalejo, F. (Fernando), Del Cristo Rodriguez-Perez, M. (María), Rodríguez-Villamizar, L.A. (Laura A.), Rojas-Martinez, R. (Rosalba), Rojroong-Wasinkul, N. (Nipa), Romaguera, D. (Dora), Ronkainen, K. (Kimmo), Rosengren, A. (Annika), Rouse, I. (Ian), Rubinstein, A. (Adolfo), Rühli, F.J. (Frank J.), Rui, O. (Ornelas), Ruiz-Betancourt, B.S. (Blanca Sandra), Russo Horimoto, A.R.V. (Andrea R. V.), Rutkowski, M. (Marcin), Sabanayagam, C. (Charumathi), Sachdev, H.S. (Harshpal S.), Saidi, O. (Olfa), Salanave, B. (Benoit), Martinez, E.S. (Eduardo Salazar), Salomaa, V. (Veikko), Salonen, J.T. (Jukka T.), Salvetti, M. (Massimo), Sánchez-Abanto, J. (Jose), Sandjaja, Sans, S. (Susana), Santos, D.A. (Diana A.), Santos, O. (Osvaldo), Dos Santos, R.N. (Renata Nunes), Santos, R. (Rute), Saramies, J. (Jouko), Sardinha, L.B. (Luis B.), Sarrafzadegan, N. (Nizal), Saum, K.-U. (Kai-Uwe), Savva, S., Scazufca, M. (Marcia), Rosario, A.S. (Angelika Schaffrath), Schargrodsky, H. (Herman), Schienkiewitz, A. (Anja), Schmidt, I.M. (Ida Maria), Schneider, I.J.C. (Ione J C), Schultsz, C. (Constance), Schutte, A.E. (Aletta E.), Sein, A.A. (Aye Aye), Sen, A. (Abhijit), Senbanjo, I.O. (Idowu O.), Sepanlou, S.G. (Sadaf G), Shalnova, S.A. (Svetlana A.), Sharma, S.K. (Sanjib K.), Shaw, J.E., Shibuya, K. (Kenji), Shin, D.W. (Dong Wook), Shin, Y. (Youchan), Shiri, R. (Rahman), Siantar, R. (Rosalynn), Sibai, A.M. (Abla M.), Silva, A.M. (Antonio M.), Silva, D.A.S. (Diego Augusto Santos), Simon, M. (Mary), Simons, J. (Judith), Simons, L.A. (Leon), Sjostrom, M. (Michael), Slowikowska-Hilczer, J. (Jolanta), Slusarczyk, P. (Przemyslaw), Smeeth, L. (Liam), Smith, M.C. (Margaret C.), Snijder, M.B. (Marieke), So, H.-K. (Hung-Kwan), Sobngwi, E. (Eugène), Söderberg, S. (Stefan), Soekatri, M.Y.E. (Moesijanti Y. E.), Solfrizzi, V. (Vincenzo), Sonestedt, E. (Emily), Song, Y. (Yi), Sørensen, T.I.A. (Thorkild), Soric, M. (Maroje), Jérome, C.S. (Charles Sossa), Soumare, A. (Aicha), Staessen, J.A. (Jan), Starc, G. (Gregor), Stathopoulou, M.G. (Maria G.), Staub, K. (Kaspar), Stavreski, B. (Bill), Steene-Johannessen, J. (Jostein), Stehle, P. (Peter), Stein, A.D. (Aryeh D.), Stergiou, G.S. (George S.), Stessman, J. (Jochanan), Stieber, J. (Jutta), Stöckl, D. (Doris), Stocks, T. (Tanja), Stokwiszewski, J. (Jakub), Stratton, G. (Gareth), Stronks, K. (Karien), Strufaldi, M.W. (Maria Wany), Sun, C.-A. (Chien-An), Sundström, J. (Johan), Sung, Y.-T. (Yn-Tz), Sunyer, J. (Jordi), Suriyawongpaisal, P. (Paibul), Swinburn, B.A. (Boyd A.), Sy, R.G. (Rody G.), Szponar, L. (Lucjan), Shyong Tai, E., Tammesoo, M.L., Tamosiunas, A. (Abdonas), Tang, L. (Line), Tang, X. (Xun), Tanser, F. (Frank), Tao, Y. (Yong), Tarawneh, M.R. (Mohammed Rasoul), Tarp, J. (Jakob), Tarqui-Mamani, C.B. (Carolina B.), Taylor, A. (Anne), Tchibindat, F. (Félicité), Theobald, H. (Holger), Thijs, L. (Lutgarde), Thuesen, L. (Leif), Tjønneland, A. (Anne), Tolonen, H.K. (Hanna K.), Tolstrup, J.S. (Janne S.), Topbas, M. (Murat), Topór-Madry, R. (Roman), Torrent, M. (Maties), Toselli, S. (Stefania), Traissac, P. (Pierre), Trichopoulou, A. (Antonia), Trichopoulos, D. (Dimitrios), Trinh, O.T.H. (Oanh T. H.), Trivedi, A. (Atul), Tshepo, L. (Lechaba), Tulloch-Reid, M.K. (Marshall K.), Tuomainen, T.-P. (Tomi-Pekka), Tuomilehto, J. (Jaakko), Turley, M.L. (Maria L.), Tynelius, P. (Per), Tzotzas, T. (Themistoklis), Tzourio, C. (Christophe), Ueda, P. (Peter), Ukoli, F.A.M. (Flora A. M.), Ulmer, H. (Hanno), Unal, B. (Belgin), Uusitalo, H.M.T. (Hannu M. T.), Valdivia, G. (Gonzalo), Vale, S. (Susana), Valvi, D. (Damaskini), Schouw, Y.T. (Yvonne) van der, Van Herck, K. (Koen), Van Minh, H. (Hoang), Rossem, L. (Lenie) van, Valkengoed, I. (Irene) van, Vanderschueren, D. (Dirk), Vanuzzo, D. (Diego), Vatten, L. (Lars), Vega, T. (Tomas), Velasquez-Melendez, G. (Gustavo), Veronesi, G. (Giovanni), Monique Verschuren, W.M., Verstraeten, R. (Roosmarijn), Victora, C.G. (Cesar G.), Viegi, G., Viet, L. (Lucie), Viikari-Juntura, E. (Eira), Vineis, P. (Paolo), Vioque, J. (Jesus), Virtanen, J.K. (Jyrki K.), Visvikis-Siest, S. (Sophie), Viswanathan, B. (Bharathi), Vollenweider, P. (Peter), Voutilainen, S. (Sari), Vrdoljak, A. (Ana), Vrijheid, M. (Martine), Wade, A.N. (Alisha N.), Wagner, A. (Aline), Walton, J. (Janette), Mohamud, W.N.W. (Wan Nazaimoon Wan), Wang, M.-D. (Ming-Dong), Wang, Q. (Qian), Wang, Y. (Ying), Goya Wannamethee, S., Wareham, N.J. (Nick), Weerasekera, D. (Deepa), Whincup, P.H. (Peter), Widhalm, K. (Kurt), Widyahening, I.S. (Indah S.), Wiecek, A. (Andrzej), Wijga, A.H. (Alet), Wilks, R.J. (Rainford J.), Willeit, J. (Johann), Wilsgaard, T. (Tom), Wojtyniak, B. (Bogdan), Wong, J.E. (Jyh Eiin), Wong, T.Y. (Tien Yin), Woo, J. (Jean), Woodward, M. (Mark), Wu, F.C.W. (Frederick C.), Wu, J. (Jianfeng), Wu, S.L. (Shou Ling), Xu, H. (Haiquan), Xu, L. (Liang), Yamborisut, U. (Uruwan), Yan, W. (Weili), Yang, X. (Xiaoguang), Yardim, N. (Nazan), Ye, X. (Xingwang), Yiallouros, P.K. (P.), Yoshihara, A. (Akihiro), You, Q.S. (Qi Sheng), Younger-Coleman, N.O. (Novie O.), Yusoff, A.F. (Ahmad F.), Zainuddin, A.A. (Ahmad A.), Zambon, S. (Sabina), Zdrojewski, T. (T.), Zeng, Y. (Yi), Zhao, D. (Dong), Zhao, W. (Wenhua), Zheng, Y. (Yingfeng), Zhou, M. (Ming), Zhu, D. (Dan), Zimmermann, E., Cisneros, J.Z. (Julio Zuñiga), Bentham, J. (James), Di Cesare, M. (Mariachiara), Stevens, G.A. (Gretchen A.), Zhou, B. (Bin), Bixby, H. (Honor), Cowan, M. (Melanie), Fortunato, L. (Léa), Bennett, J.E. (James E.), Danaei, G. (Goodarz), Hajifathalian, K. (Kaveh), Lu, Y. (Yuan), Riley, L.M. (Leanne M.), Laxmaiah, A. (Avula), Kontis, V. (Vasilis), Paciorek, C.J. (Christopher J.), Ezzati, M. (Majid), Abdeen, Z.A. (Ziad A.), Hamid, Z.A. (Zargar Abdul), Abu-Rmeileh, N.M. (Niveen M.), Acosta-Cazares, B. (Benjamin), Adams, R. (Robert), Aekplakorn, W. (Wichai), Aguilar-Salinas, C.A. (Carlos), Agyemang, C.O. (Charles), Ahmadvand, A. (Alireza), Ahrens, W. (W.), Al-Hazzaa, H.M. (Hazzaa M.), Al-Othman, A.R. (Amani Rashed), Raddadi, R.A. (Rajaa Al), Ali, M.M. (Mohamed M.), Alkerwi, A. (Ala’a), Alvarez-Pedrerol, M. (Mar), Aly, E. (Eman), Amouyel, P. (Philippe), Amuzu, A. (Antoinette), Andersen, L.B. (Lars Bo), Anderssen, S.A. (Sigmund A.), Anjana, R.M. (Ranjit Mohan), Aounallah-Skhiri, H. (Hajer), Ariansen, I. (Inger), Aris, T. (Tahir), Arlappa, N. (Nimmathota), Arveiler, D. (Dominique), Assah, F.K. (Felix K.), Avdicová, M. (Mária), Azizi, J. (Joshan), Babu, B.V. (Bontha V.), Bahijri, S. (Suhad), Balakrishna, N. (Nagalla), Bandosz, P. (Piotr), Banegas, J.R. (José R.), Barbagallo, C.M. (Carlo M.), Barceló, A. (Alberto), Barkat, A. (Amina), Barros, M.V. (Mauro V.), Bata, I. (Iqbal), Batieha, A.M. (Anwar M.), Batista, R.L. (Rosangela L.), Baur, L.A. (Louise A.), Beaglehole, R. (Robert), Romdhane, H.B. (Habiba Ben), Benet, M. (Mikhail), Bernabe-Ortiz, A. (Antonio), Bernotiene, G. (Gailute), Bettiol, H. (Heloisa), Bhagyalaxmi, A. (Aroor), Bharadwaj, S. (Sumit), Bhargava, S.K. (Santosh K.), Bhatti, Z. (Zaid), Bhutta, Z.A. (Zulfiqar A), Bi, H. (Hongsheng), Bi, Y. (Yufang), Bjerregaard, P. (Peter), Bjertness, E. (Espen), Bjertness, M.B. (Marius B.), Björkelund, C. (Cecilia), Blokstra, A. (Anneke), Bo, S. (Simona), Bobak, M. (Martin), Boddy, L.M. (Lynne M.), Boehm, B.O. (Bernhard), Boeing, H. (Heiner), Boissonnet, C.P. (Carlos P.), Bongard, V. (Vanina), Bovet, P. (Pascal), Braeckman, L. (Lutgart), Bragt, M.C.E. (Marjolijn C. E.), Brajkovich, I. (Imperia), Branca, F. (Francesco), Breckenkamp, J. (Juergen), Brenner, H. (Hermann), Brewster, L.M. (Lizzy), Brian, G.R. (Garry R.), Bruno, G. (Graziella), Bueno-de-Mesquita, H.B. (H. Bas), Bugge, A. (Anna), Burns, C. (Con), De León, A.C. (Antonio Cabrera), Cacciottolo, J. (Joseph), Cama, T. (Tilema), Cameron, C. (Christine), Camolas, J. (José), Can, G. (Günay), Cândido, A.P.C. (Ana Paula C.), Capuano, V. (Vincenzo), Cardoso, V.C. (Viviane C.), Carlsson, A.C. (Axel C.), Carvalho, M.J. (Maria J.), Casanueva, F.F. (Felipe F.), Casas, J.P. (Juan Pablo), Caserta, C.A. (Carmelo A.), Chamukuttan, S. (Snehalatha), Chan, A.W.M. (Angelique), Chan, Q. (Queenie), Chaturvedi, H.K. (Himanshu K.), Chaturvedi, N. (Nishi), Chen, C.-J. (Chien-Jen), Chen, F. (Fangfang), Chen, H. (Huashuai), Chen, S. (Shuohua), Chen, Z. (Zhengming), Cheng, C.-Y. (Ching-Yu), Chetrit, A. (Angela), Chiolero, A. (Arnaud), Chiou, S.-T. (Shu-Ti), Chirita-Emandi, A. (Adela), Cho, B. (Belong), Cho, Y. (Yumi), Christensen, K. (Kaare), Chudek, J. (Jerzy), Cifkova, R. (Renata), Claessens, F., Clays, E. (Els), Concin, H. (Hans), Cooper, C. (Charles), Cooper, R. (Rachel), Coppinger, T.C. (Tara C.), Costanzo, S. (Simona), Cottel, D. (Dominique), Cowell, C. (Chris), Craig, C.L. (Cora L.), Crujeiras, A.B. (Ana B.), D’Arrigo, G. (Graziella), d’Orsi, E. (Eleonora), Dallongeville, J., Damasceno, A. (Albertino), Damsgaard, C.T. (Camilla T.), Dankner, R. (Rachel), Dauchet, L. (Luc), De Backer, G. (Guy), De Bacquer, D. (Dirk), de Gaetano, G. (Giovanni), De Henauw, S. (Stefaan), De Smedt, D. (Delphine), Deepa, M. (Mohan), Deev, A.D. (Alexander D.), Dehghan, A. (Abbas), Delisle, H. (Hélène), Delpeuch, F. (Francis), Deschamps, V. (Valérie), Dhana, K. (Klodian), Di Castelnuovo, A.F. (Augusto F.), Dias-da-Costa, J.S. (Juvenal Soares), Diaz, A. (Alejandro), Djalalinia, S. (Shirin), Do, H.T.P. (Ha T. P.), Dobson, A.J. (Annette J.), Donfrancesco, C. (Chiara), Donoso, S.P. (Silvana P.), Döring, A. (Angela), Doua, K. (Kouamelan), Drygas, W. (Wojciech), Dzerve, V. (Vilnis), Egbagbe, E.E. (Eruke E.), Eggertsen, R. (Robert), Ekelund, U. (Ulf), El Ati, J. (Jalila), Elliott, P. (Paul), Engle-Stone, R. (Reina), Erasmus, R.T. (Rajiv T.), Erem, C. (Cihangir), Eriksen, L. (Louise), Escobedo-de la Peña, J. (Jorge), Evans, A. (Alun), Faeh, D. (David), Fall, C.H. (Caroline H.), Farzadfar, F. (Farshad), Felix-Redondo, F.J. (Francisco J.), Ferguson, T.S. (Trevor S.), Fernández-Bergés, D. (Daniel), Ferrante, D. (Daniel), Ferrari, M. (Marika), Ferreccio, C. (Catterina), Ferrieres, J. (Jean), Finn, J.D. (Joseph D.), Fischer, K. (Krista), Flores, E.M. (Eric Monterubio), Föger, B. (Bernhard), Foo, L.H. (Leng Huat), Forslund, A.-S. (Ann-Sofie), Forsner, M. (Maria), Fortmann, S.P. (Stephen), Fouad, H.M. (Heba M.), Francis, D.K. (Damian K.), Do Carmo Franco, M. (Maria), Franco, O.H. (Oscar), Frontera, G. (Guillermo), Fuchs, F.D. (Flavio D.), Fuchs, S.C. (Sandra C.), Fujita, Y. (Yuki), Furusawa, T. (Takuro), Gaciong, Z. (Zbigniew), Gafencu, M. (Mihai), Gareta, D. (Dickman), Garnett, S.P. (Sarah P.), Gaspoz, J.-M. (Jean-Michel), Gasull, M. (Magda), Gates, L. (Louise), Geleijnse, J.M. (Marianne), Ghasemian, A. (Anoosheh), Giampaoli, S. (Simona), Gianfagna, F. (Francesco), Giovannelli, J. (Jonathan), Giwercman, A. (Aleksander), Goldsmith, R.A. (Rebecca A.), Gonçalves, H. (Helen), Gross, M., González Rivas, J.P. (Juan P.), Gorbea, M.B. (Mariano Bonet), Gottrand, F. (Frederic), Graff-Iversen, S. (Sidsel), Grafnetter, D. (Dušan), Grajda, A. (Aneta), Grammatikopoulou, M.G. (Maria G.), Gregor, R.D. (Ronald D.), Grodzicki, T. (Tomasz), Grøntved, A. (Anders), Gruden, G. (Grabriella), Grujic, V. (Vera), Gu, D. (Dongfeng), Gualdi-Russo, E. (Emanuela), Guan, O.P. (Ong Peng), Gudnason, V. (Vilmundur), Guerrero, R. (Ramiro), Guessous, I. (Idris), Guimaraes, A.L. (Andre L.), Gulliford, M.C. (Martin C.), Gunnlaugsdottir, J. (Johanna), Gunter, M. (Marc), Guo, X. (Xiuhua), Guo, Y. (Yin), Gupta, P.C. (Prakash C.), Gureje, O. (Oye), Gurzkowska, B. (Beata), Gutierrez, L. (Laura), Gutzwiller, F. (Felix), Halkjær, J., Hambleton, I.R. (Ian R.), Hardy, R., Kumar, R.H. (Rachakulla Hari), Hata, J. (Jun), Hayes, A.J. (Alison J.), He, J. (Jiang), Hendriks, M.E. (Marleen), Cadena, L.H. (Leticia Hernandez), Herrala, S. (Sauli), Heshmat, R. (Ramin), Hihtaniemi, I.T. (Ilpo Tapani), Ho, S.Y. (Sai Yin), Ho, S.C. (Suzanne C.), Hobbs, M. (Michael), Hofman, A. (Albert), Hormiga, C.M. (Claudia M.), Horta, B.L. (Bernardo L.), Houti, L. (Leila), Howitt, C. (Christina), Htay, T.T. (Thein Thein), Htet, A.S. (Aung Soe), Htike, M.M.T. (Maung Maung Than), Hu, Y. (Yonghua), Husseini, A. (Abdullatif), Huu, C.N. (Chinh Nguyen), Huybrechts, I. (Inge), Hwalla, N. (Nahla), Iacoviello, L. (Licia), Iannone, A.G. (Anna G.), Ibrahim, M.M. (Mohsen M.), Ikeda, N. (Nayu), Ikram, M.A. (Arfan), Irazola, V. (Vilma), Islam, M. (Muhammad), Ivkovic, V. (Vanja), Iwasaki, M. (Masanori), Jackson, R.T. (Rod T.), Jacobs, J.M. (Jeremy M.), Jafar, T.H. (Tazeen), Jamil, K.M. (Kazi M.), Jamrozik, K., Janszky, I. (Imre), Jasienska, G. (Grazyna), Jelakovic, B. (Bojan), Jiang, C.Q. (Chao Qiang), Joffres, M. (Michel), Johansson, M. (Mattias), Jonas, J.B. (Jost B.), Jorgensen, T. (Torben), Joshi, P. (Pradeep), Juolevi, A. (Anne), Jurak, G. (Gregor), Jureša, V. (Vesna), Kaaks, R. (Rudolf), Kafatos, A. (Anthony), Kalter-Leibovici, O. (Ofra), Kapantais, E. (Efthymios), Kasaeian, A. (Amir), Katz, J. (Joanne), Kaur, P. (Prabhdeep), Kavousi, M. (Maryam), Keil, M. (Mark), Boker, L.K. (Lital Keinan), Keinanen-Kiukaanniemi, S. (Sirkka), Kelishadi, R. (Roya), Kemper, H.C.G., Kengne, A.P. (Andre Pascal), Kersting, M. (Mathilde), Key, T. (Tim), Khader, Y.S. (Yousef Saleh), Khalili, D. (Davood), Khang, Y.-H. (Young-Ho), Khaw, K.-T. (Kay-Tee), Khouw, I.M.S.L. (Ilse M. S. L.), Kiechl, S. (Stefan), Killewo, J. (Japhet), Kim, J. (Jeongseon), Klimont, J. (Jeannette), Klumbiene, J. (Jurate), Koirala, B. (Bhawesh), Kolle, E. (Elin), Kolsteren, P. (Patrick), Korrovits, P. (Paul), Koskinen, S. (Seppo), Kouda, K. (Katsuyasu), Koziel, S. (Slawomir), Kratzer, W. (Wolfgang), Krokstad, S. (Steinar), Kromhout, D. (Daan), Kruger, H.S. (Herculina S.), Kubinova, R., Kujala, U.M. (Urho), Kula, K. (Krzysztof), Kulaga, Z. (Zbigniew), Krishna Kumar, R., Kurjata, P. (Pawel), Kusuma, Y.S. (Yadlapalli S.), Kuulasmaa, K. (Kari), Kyobutungi, C. (Catherine), Laamiri, F.Z. (Fatima Zahra), Laatikainen, T. (Tiina), Lachat, C. (Carl), Laid, Y. (Youcef), Lam, T.H. (Tai Hing), Landrove, O. (Orlando), Lanska, V. (Vera), Lappas, G. (Georg), Larijani, B. (Bagher), Laugsand, L.E. (Lars E.), Bao, K.L.N. (Khanh Le Nguyen), Le, T.D. (Tuyen D.), Leclercq, C. (Catherine), Lee, J.J.M. (Jeannette), Lee, J. (Jeonghee), Lehtimäki, T. (Terho), Lekhraj, R. (Rampal), León-Muñoz, L.M. (Luz M.), Li, Y. (Yanping), Lilly, C.L. (Christa L.), Lim, W.-Y. (Wei-Yen), Fernanda Lima-Costa, M., Lin, H.-H. (Hsien-Ho), Lin, X. (Xu), Linneberg, A. (Allan), Lissner, L. (Lauren), Litwin, M. (Mieczyslaw), Liu, J. (Jing), Lorbeer, R. (Roberto), Lotufo, P.A. (Paulo A), Lozano, J.E. (José Eugenio), Luksiene, D. (Dalia), Lundqvist, A. (Annamari), Lunet, N. (Nuno), Lytsy, P. (Per), Ma, G. (Guansheng), Ma, J. (Jun), Machado-Coelho, G.L.L. (George L. L.), Machi, S. (Suka), Maggi, S. (Stefania), Magliano, D.J., Maire, B. (Bernard), Makdisse, M. (Marcia), Malekzadeh, R. (Reza), Malhotra, R. (Rahul), Rao, K.M. (Kodavanti Mallikharjuna), Malyutina, S., Manios, Y., Mann, J.I. (Jim I.), Manzato, E. (Enzo), Margozzini, P. (Paula), Markey, O. (Oonagh), Marques-Vidal, P. (Pedro), Marrugat, J. (Jaume), Martin-Prevel, Y. (Yves), Martorell, R. (Reynaldo), Masoodi, S.R. (Shariq R.), Mathiesen, E.B. (Ellisiv), Matsha, T.E. (Tandi E.), Mazur, A. (Artur), Mbanya, J.C.N. (Jean Claude N.), McFarlane, S.R. (Shelly R.), McGarvey, S.T. (Stephen T.), McKee, M. (Martin), McLachlan, S. (Stela), McLean, R.M. (Rachael M.), McNulty, B.A. (Breige A.), Yusof, S.M. (Safiah Md), Mediene-Benchekor, S. (Sounnia), Meirhaeghe, A. (Aline), Meisinger, C. (Christa), Menezes, A.M.B. (Ana Maria B.), Mensink, G.B.M. (Gert B. M.), Meshram, I.I. (Indrapal I.), Metspalu, A. (Andres), Mi, J. (Jie), Michaelsen, K.F., Mikkel, K. (Kairit), Miller, J.C. (Jody C.), Miquel, J.F. (Juan Francisco), Jaime Miranda, J., Mišigoj-Durakovic, M. (Marjeta), Mohamed, M.K. (Mostafa K.), Mohammad, K. (Kazem), Mohammadifard, N. (Noushin), Mohan, V. (Viswanathan), Yusoff, M.F.M. (Muhammad Fadhli Mohd), Molbo, D. (Drude), Møller, N.C. (Niels C.), Molnár, D. (Dénes), Mondo, C.K. (Charles K.), Monterrubio, E.A. (Eric A.), Monyeki, K.D.K. 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(Davide), Nsour, M.A. (Mohannad Al), O’Reilly, D. (Dermot), Oh, K. (Kyungwon), Olayan, I.H. (Iman H.), Olinto, M.T.A. (Maria Teresa Anselmo), Oltarzewski, M. (Maciej), Omar, M.A. (Mohd A.), Onat, A. (Altan), Ordunez, P. (Pedro), Ortiz, A.P. (Ana P.), Osler, M. (Merete), Osmond, C. (Clive), Ostojic, S.M. (Sergej M.), Otero, J.A. (Johanna A.), Overvad, K. (Kim), Owusu-Dabo, E. (Ellis), Paccaud, F.M. (Fred Michel), Padez, C. (Cristina), Pahomova, E. (Elena), Pajak, A. (Andrzej), Palli, D. (Domenico), Palloni, A. (Alberto), Palmieri, L. (Luigi), Panda-Jonas, S. (Songhomitra), Panza, F. (Francesco), Parnell, W.R. (Winsome R.), Parsaeian, M. (Mahboubeh), Pecin, I. (Ivan), Pednekar, M.S. (Mangesh S.), Peeters, P.H.M., Peixoto, S.V. (Sergio Viana), Peltonen, M. (Markku), Pereira, A. (A.), Pérez, C.M. (Cynthia M.), Peters, A., Petkeviciene, J. (Janina), Peykari, N. (Niloofar), Pham, S.T. (Son Thai), Pigeot, I. (Iris), Pikhart, H. (Hynek), Pilav, A. (Aida), Pilotto, A. (Alberto), Pistelli, F. (Francesco), Pitakaka, F. (Freda), Piwonska, A. (Aleksandra), Plans-Rubió, P. (Pedro), Poh, B.K. (Bee Koon), Porta, M., Portegies, M.L.P. (Marileen), Poulimeneas, D. (Dimitrios), Pradeepa, R. (Rajendra), Prashant, M. (Mathur), Price, J.F. (Jackie F.), Puiu, M. (Maria), Punab, M. (Margus), Qasrawi, R.F. (Radwan F.), Qorbani, M. (Mostafa), Bao, T.Q. (Tran Quoc), Radic, I. (Ivana), Radisauskas, R. (Ricardas), Rahman, M.-M. (Mah-mudur), Raitakari, O. (Olli), Raj, M. (Manu), Rao, S.R. (Sudha Ramachandra), Ramachandran, A. (Ambady), Ramke, J. (Jacqueline), Ramos, R. (Rafel), Rampal, S. (Sanjay), Rasmussen, F. (Finn), Redón, J. (Josep), Reganit, P.F.M. (Paul Ferdinand M.), Ribeiro, R. (Robespierre), Riboli, E. (Elio), Rigo, F. (Fernando), Rinke de Wit, T.F. (Tobias), Ritti-Dias, R.M. (Raphael M.), Rivera, J.A. (Juan A.), Robinson, S.M. (Siân), Robitaille, C. (Cynthia), Rodríguez Artalejo, F. (Fernando), Del Cristo Rodriguez-Perez, M. (María), Rodríguez-Villamizar, L.A. 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(Jyrki K.), Visvikis-Siest, S. (Sophie), Viswanathan, B. (Bharathi), Vollenweider, P. (Peter), Voutilainen, S. (Sari), Vrdoljak, A. (Ana), Vrijheid, M. (Martine), Wade, A.N. (Alisha N.), Wagner, A. (Aline), Walton, J. (Janette), Mohamud, W.N.W. (Wan Nazaimoon Wan), Wang, M.-D. (Ming-Dong), Wang, Q. (Qian), Wang, Y. (Ying), Goya Wannamethee, S., Wareham, N.J. (Nick), Weerasekera, D. (Deepa), Whincup, P.H. (Peter), Widhalm, K. (Kurt), Widyahening, I.S. (Indah S.), Wiecek, A. (Andrzej), Wijga, A.H. (Alet), Wilks, R.J. (Rainford J.), Willeit, J. (Johann), Wilsgaard, T. (Tom), Wojtyniak, B. (Bogdan), Wong, J.E. (Jyh Eiin), Wong, T.Y. (Tien Yin), Woo, J. (Jean), Woodward, M. (Mark), Wu, F.C.W. (Frederick C.), Wu, J. (Jianfeng), Wu, S.L. (Shou Ling), Xu, H. (Haiquan), Xu, L. (Liang), Yamborisut, U. (Uruwan), Yan, W. (Weili), Yang, X. (Xiaoguang), Yardim, N. (Nazan), Ye, X. (Xingwang), Yiallouros, P.K. (P.), Yoshihara, A. (Akihiro), You, Q.S. (Qi Sheng), Younger-Coleman, N.O. (Novie O.), Yusoff, A.F. (Ahmad F.), Zainuddin, A.A. (Ahmad A.), Zambon, S. (Sabina), Zdrojewski, T. (T.), Zeng, Y. (Yi), Zhao, D. (Dong), Zhao, W. (Wenhua), Zheng, Y. (Yingfeng), Zhou, M. (Ming), Zhu, D. (Dan), Zimmermann, E., and Cisneros, J.Z. (Julio Zuñiga)
Abstract: Being taller is associated with enhanced longevity, and higher education and earnings. We reanalysed 1472 population-based studies, with measurement of height on more than 18.6 million participants to estimate mean height for people born between 1896 and 1996 in 200 countries. The largest gain in adult height over the past century has occurred in South Korean women and Iranian men, who became 20.2 cm (95% credible interval 17.5-22.7) and 16.5 cm (13.3- 19.7) taller, respectively. In contrast, there was little change in adult height in some sub-Saharan African countries and in South Asia over the century of analysis. The tallest people over these 100 years are men born in the Netherlands in the last quarter of 20th century, whose average heights surpassed 182.5 cm, and the shortest were women born in Guatemala in 1896 (140.3 cm; 135.8- 144.8). The height differential between the tallest and shortest populations was 19-20 cm a century ago, and has remained the same for women and increased for men a century later despite substantial changes in the ranking of countries.
Published: 2016
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14. Trends in adult body-mass index in 200 countries from 1975 to 2014: A pooled analysis of 1698 population-based measurement studies with 19.2 million participants

Author: Di Cesare, M. (Mariachiara), Bentham, J. (James), Stevens, G.A. (Gretchen A.), Zhou, B. (Bin), Danaei, G. (Goodarz), Lu, Y. (Yuan), Bixby, H. (Honor), Cowan, M.J. (Melanie J.), Riley, L.M. (Leanne M.), Hajifathalian, K. (Kaveh), Fortunato, L. (Léa), Taddei, C. (Cristina), Bennett, J.E. (James E.), Ikeda, N. (Nayu), Khang, Y.-H. (Young-Ho), Kyobutungi, C. (Catherine), Laxmaiah, A. (Avula), Li, Y. (Yanping), Lin, H.-H. (Hsien-Ho), Miranda, J.J. (J. Jaime), Mostafa, A. (Aya), Turley, M.L. (Maria L.), Paciorek, C.J. (Christopher J.), Gunter, M. (Marc), Ezzati, M. (Majid), Abdeen, Z.A. (Ziad A.), Hamid, Z.A. (Zargar Abdul), Abu-Rmeileh, N.M. (Niveen M.), Acosta-Cazares, B. (Benjamin), Adams, R. (Robert), Aekplakorn, W. (Wichai), Aguilar-Salinas, C.A. (Carlos), Ahmadvand, A. (Alireza), Ahrens, W. (W.), Ali, M.M. (Mohamed M.), Alkerwi, A. (Ala'a), Alvarez-Pedrerol, M. (Mar), Aly, E. (Eman), Amouyel, P. (Philippe), Amuzu, A. (Antoinette), Andersen, L.B. (Lars Bo), Anderssen, S.A. (Sigmund A.), Andrade, D.S. (Dolores S.), Anjana, R.M. (Ranjit Mohan), Aounallah-Skhiri, H. (Hajer), Ariansen, I. (Inger), Aris, T. (Tahir), Arlappa, N. (Nimmathota), Arveiler, D. (Dominique), Assah, F.K. (Felix K.), Avdicová, M. (Mária), Azizi, J. (Joshan), Babu, B.V. (Bontha V.), Balakrishna, N. (Nagalla), Bandosz, P. (Piotr), Banegas, J.R. (José R.), Barbagallo, C.M. (Carlo M.), Barceló, A. (Alberto), Barkat, A. (Amina), Barros, M.V. (Mauro V.), Bata, I. (Iqbal), Batieha, A.M. (Anwar M.), Batista, R.L. (Rosangela L.), Baur, L.A. (Louise A.), Beaglehole, R. (Robert), Romdhane, H.B. (Habiba Ben), Benet, M. (Mikhail), Bernabe-Ortiz, A. (Antonio), Bernotiene, G. (Gailute), Bettiol, H. (Heloisa), Bhagyalaxmi, A. (Aroor), Bharadwaj, S. (Sumit), Bhargava, S.K. (Santosh K.), Bhatti, Z. (Zaid), Bhutta, Z.A. (Zulfiqar A), Bi, H. (HongSheng), Bi, Y. (Yufang), Bjerregaard, P. (Peter), Bjertness, E. (Espen), Bjertness, M.B. (Marius B.), Björkelund, C. (Cecilia), Blake, M. (Margaret), Blokstra, A. (Anneke), Bo, S. (Simona), Bobak, M. (Martin), Boddy, L.M. (Lynne M.), Boehm, B.O. (Bernhard), Boeing, H. (Heiner), Boissonnet, C.P. (Carlos P.), Bongard, V. (Vanina), Bovet, P. (Pascal), Braeckman, L. (Lutgart), Bragt, M.C.E. (Marjolijn C.E.), Brajkovich, I. (Imperia), Branca, F. (Francesco), Breckenkamp, J. (Juergen), Brenner, H. (Hermann), Brewster, L.M. (Lizzy), Brian, G.R. (Garry R.), Bruno, G. (Graziella), Bueno-De-Mesquita, H.B., Bugge, A. (Anna), Burns, C. (Con), De León, A.C. (Antonio Cabrera), Cacciottolo, J. (Joseph), Cama, T. (Tilema), Cameron, C. (Christine), Camolas, J. (José), Can, G. (Günay), Cândido, A.P.C. (Ana Paula C.), Capuano, V. (Vincenzo), Cardoso, V.C. (Viviane C.), Carvalho, M.J. (Maria J.), Casanueva, F.F. (Felipe F.), Casas, J.P. (Juan Pablo), Caserta, C.A. (Carmelo A.), Castetbon, K., Chamukuttan, S. (Snehalatha), Chan, A.W. (Angelique W.), Chan, Q. (Queenie), Chaturvedi, H.K. (Himanshu K.), Chaturvedi, N. (Nishi), Chen, C.-J. (Chien-Jen), Chen, F. (Fangfang), Chen, H. (Huashuai), Chen, S. (Shuohua), Chen, Z. (Zhengming), Cheng, C.-Y. (Ching-Yu), Chetrit, A. (Angela), Chiolero, A. (Arnaud), Chiou, S.-T. (Shu-Ti), Chirita-Emandi, A. (Adela), Cho, Y. (Yumi), Christensen, K. (Kaare), Chudek, J. (Jerzy), Cifkova, R. (Renata), Claessens, F., Clays, E. (Els), Concin, H. (Hans), Cooper, C. (Charles), Cooper, R. (Rachel), Coppinger, T.C. (Tara C.), Costanzo, S. (Simona), Cottel, D. (Dominique), Cowell, C. (Chris), Craig, C.L. (Cora L.), Crujeiras, A.B. (Ana B.), D'Arrigo, G. (Graziella), D'Orsi, E. (Eleonora), Dallongeville, J., Damasceno, A. (Albertino), Damsgaard, C.T. (Camilla T.), Dankner, R. (Rachel), Dauchet, L. (Luc), De Backer, G. (Guy), De Bacquer, D. (Dirk), De Gaetano, G. (Giovanni), De Henauw, S. (Stefaan), De Smedt, D. (Delphine), Deepa, M. (Mohan), Deev, A.D. (Alexander D.), Dehghan, A. (Abbas), Delisle, H. (Hélène), Delpeuch, F. (Francis), Dhana, K. (Klodian), Di Castelnuovo, A.F. (Augusto F.), Dias-Da-Costa, J.S. (Juvenal Soares), Diaz, A. (Alejandro), Djalalinia, S. (Shirin), Do, H.T.P. (Ha T.P.), Dobson, A.J. (Annette J.), Donfrancesco, C. (Chiara), Döring, A. (Angela), Doua, K. (Kouamelan), Drygas, W. (Wojciech), Egbagbe, E.E. (Eruke E.), Eggertsen, R. (Robert), Ekelund, U. (Ulf), El Ati, J. (Jalila), Elliott, P. (Paul), Engle-Stone, R. (Reina), Erasmus, R.T. (Rajiv T.), Erem, C. (Cihangir), Eriksen, L. (Louise), De La Peña, J.E. (Jorge Escobedo), Evans, A. (Alun), Faeh, D. (David), Fall, C.H. (Caroline H.), Farzadfar, F. (Farshad), Felix-Redondo, F.J. (Francisco J.), Ferguson, T.S. (Trevor S.), Fernández-Bergés, D. (Daniel), Ferrante, D. (Daniel), Ferrari, M. (Marika), Ferreccio, C. (Catterina), Ferrieres, J. (Jean), Finn, J.D. (Joseph D.), Fischer, K. (Krista), Flores, E.M. (Eric Monterubio), Föger, B. (Bernhard), Foo, L.H. (Leng Huat), Forslund, A.-S. (Ann-Sofie), Fortmann, S.P. (Stephen), Fouad, H.M. (Heba M.), Francis, D.K. (Damian K.), Do Carmo Franco, M. (Maria), Franco, O.H. (Oscar), Frontera, G. (Guillermo), Fuchs, F.D. (Flavio D.), Fuchs, S.C. (Sandra C.), Fujita, Y. (Yuki), Furusawa, T. (Takuro), Gaciong, Z. (Zbigniew), Gafencu, M. (Mihai), Gareta, D. (Dickman), Garnett, S.P. (Sarah P.), Gaspoz, J.-M. (Jean-Michel), Gasull, M. (Magda), Gates, L. (Louise), Geleijnse, J.M. (Marianne), Ghasemian, A. (Anoosheh), Giampaoli, S. (Simona), Gianfagna, F. (Francesco), Giovannelli, J. (Jonathan), Giwercman, A. (Aleksander), Goldsmith, R.A. (Rebecca A.), Gross, M., Rivas, J.P.G. (Juan P. González), Gorbea, M.B. (Mariano Bonet), Gottrand, F. (Frederic), Graff-Iversen, S. (Sidsel), Grafnetter, D. (Dušan), Grajda, A. (Aneta), Grammatikopoulou, M.G. (Maria G.), Gregor, R.D. (Ronald D.), Grodzicki, T. (Tomasz), Grøntved, A. (Anders), Gruden, G. (Grabriella), Grujic, V. (Vera), Gu, D. (Dongfeng), Guan, O.P. (Ong Peng), Gudnason, V. (Vilmundur), Guerrero, R. (Ramiro), Guessous, I. (Idris), Guimaraes, A.L. (Andre L.), Gulliford, M.C. (Martin C.), Gunnlaugsdottir, J. (Johanna), Guo, X.H. (Xiu H.), Guo, Y. (Yin), Gupta, P.C. (Prakash C.), Gureje, O. (Oye), Gurzkowska, B. (Beata), Gutierrez, L. (Laura), Gutzwiller, F. (Felix), Halkjær, J., Hardy, R., Kumar, R.H. (Rachakulla Hari), Hayes, A.J. (Alison J.), He, J. (Jiang), Hendriks, M.E. (Marleen), Cadena, L.H. (Leticia Hernandez), Heshmat, R. (Ramin), Hihtaniemi, I.T. (Ilpo Tapani), Ho, S.Y. (Sai Yin), Ho, S.C. (Suzanne C.), Hobbs, M. (Michael), Hofman, A. (Albert), Hormiga, C.M. (Claudia M.), Horta, B.L. (Bernardo L.), Houti, L. (Leila), Htay, T.T. (Thein Thein), Htet, A.S. (Aung Soe), Htike, M.M.T. (Maung Maung Than), Hu, Y. (Yonghua), Hussieni, A.S. (Abdullatif S.), Huu, C.N. (Chinh Nguyen), Huybrechts, I. (Inge), Hwalla, N. (Nahla), Iacoviello, L. (Licia), Iannone, A.G. (Anna G.), Ibrahim, M.M. (M. Mohsen), Ikram, M.A. (Arfan), Irazola, V. (Vilma), Islam, M. (Muhammad), Iwasaki, M. (Masanori), Jackson, R.T. (Rod T.), Jacobs, J.M. (Jeremy M.), Jafar, T.H. (Tazeen), Jamil, K.M. (Kazi M.), Jamrozik, K., Jasienska, G. (Grazyna), Jiang, C.Q. (Chao Qiang), Joffres, M. (Michel), Johansson, M. (Mattias), Jonas, J.B. (Jost B.), Jorgensen, T. (Torben), Joshi, P. (Pradeep), Juolevi, A. (Anne), Jurak, G. (Gregor), Jureša, V. (Vesna), Kaaks, R. (Rudolf), Kafatos, A. (Anthony), Kalter-Leibovici, O. (Ofra), Kapantais, E. (Efthymios), Kasaeian, A. (Amir), Katz, J. (Joanne), Kaur, P. (Prabhdeep), Kavousi, M. (Maryam), Keil, M. (Mark), Boker, L.K. (Lital Keinan), Kelishadi, R. (Roya), Kemper, H.H.C.G. (Han H.C.G.), Kengne, A.P. (Andre Pascal), Kersting, M. (Mathilde), Key, T. (Timothy), Khader, Y.S. (Yousef Saleh), Khalili, D. (Davood), Khaw, K.-T. (Kay-Tee), Khouw, I.M.S.L. (Ilse M.S.L.), Kiechl, S. (Stefan), Killewo, J. (Japhet), Kim, J. (Jeongseon), Kiyohara, Y. (Yutaka), Klimont, J. (Jeannette), Kolle, E. (Elin), Kolsteren, P. (Patrick), Korrovits, P. (Paul), Koskinen, S. (Seppo), Kouda, K. (Katsuyasu), Koziel, S. (Slawomir), Kratzer, W. (Wolfgang), Krokstad, S. (Steinar), Kromhout, D. (Daan), Kruger, H.S. (Herculina S.), Kula, K. (Krzysztof), Kulaga, Z. (Zbigniew), Kumar, R.K. (R. Krishna), Kusuma, Y.S. (Yadlapalli S.), Kuulasmaa, K. (Kari), Laamiri, F.Z. (Fatima Zahra), Laatikainen, T. (Tiina), Lachat, C. (Carl), Laid, Y. (Youcef), Lam, T.H. (Tai Hing), Landrove, O. (Orlando), Lanska, V. (Vera), Lappas, G. (Georg), Laugsand, L.E. (Lars E.), Le Nguyen Bao, K. (Khanh), Le, T.D. (Tuyen D.), Leclercq, C. (Catherine), Lee, J. (Jeannette), Lee, J. (Jeonghee), Lehtimäki, T. (Terho), Lekhraj, R. (Rampal), León-Munoz, L.M. (Luz M.), Lim, W.-Y. (Wei-Yen), Lima-Costa, M.F. (M. Fernanda), Lin, X. (Xu), Linneberg, A. (Allan), Lissner, L. (Lauren), Litwin, M. (Mieczyslaw), Liu, J. (Jing), Lorbeer, R. (Roberto), Lotufo, P.A. (Paulo A), Lozano, J.E. (José Eugenio), Luksiene, D. (Dalia), Lundqvist, A. (Annamari), Lunet, N. (Nuno), Lytsy, P. (Per), Ma, G. (Guansheng), Machi, S. (Suka), Maggi, S. (Stefania), Magliano, D.J., Makdisse, M. (Marcia), Malekzadeh, R. (Reza), Malhotra, R. (Rahul), Rao, K.M. (Kodavanti Mallikharjuna), Manios, Y., Mann, J.I. (Jim I.), Manzato, E. (Enzo), Margozzini, P. (Paula), Markey, O. (Oonagh), Marques-Vidal, P. (Pedro), Marrugat, J. (Jaume), Martin-Prevel, Y. (Yves), Martorell, R. (Reynaldo), Masoodi, S.R. (Shariq R.), Matsha, T.E. (Tandi E.), Mazur, A. (Artur), Mbanya, J.C.N. (Jean Claude N.), McFarlane, S.R. (Shelly R.), McGarvey, S.T. (Stephen T.), McKee, M. (Martin), McLachlan, S. (Stela), McLean, R.M. (Rachael M.), McNulty, B.A. (Breige A.), Md Yusof, S. (Safiah), Mediene-Benchekor, S. (Sounnia), Meirhaeghe, A. (Aline), Meisinger, C. (Christa), Mendes, L.L. (Larissa L.), Menezes, A.M.B. (Ana Maria B.), Mensink, G.B.M. (Gert B.M.), Meshram, I.I. (Indrapal I.), Metspalu, A. (Andres), Mi, J. (Jie), Michaelsen, K.F., Mikkel, K. (Kairit), Miller, J.C. (Jody C.), Miquel, J.F. (Juan Francisco), Mišigoj-Duraković, M. (Marjeta), Mohamed, M.K. (Mostafa K.), Mohammad, K. (Kazem), Mohammadifard, N. (Noushin), Mohan, V. (Viswanathan), Yusoff, M.F.M. (Muhammad Fadhli Mohd), Molbo, D. (Drude), Møller, N.C. (Niels C.), Molnár, D. (Dénes), Mondo, C.K. (Charles K.), Monterrubio, E.A. (Eric A.), Monyeki, K.D.K. (Kotsedi Daniel K.), Moreira, L.B. (Leila B.), Morejon, A. (Alain), Moreno, L.A. (Luis A.), Morgan, K. (Karen), Mortensen, E.L. (Erik Lykke), Moschonis, G., Mossakowska, M. (Malgorzata), Mota, J. (Jorge), Motlagh, M.E. (Mohammad Esmaeel), Motta, J. (Jorge), Mu, T.T. (Thet Thet), Muiesan, M.L. (Maria Lorenza), Müller-Nurasyid, M. (Martina), Murphy, N. (Neil), Mursu, J. (Jaakko), Murtagh, E.M. (Elaine M.), Musa, K.I. (Kamarul Imran), Musil, V. (Vera), Nagel, G. (Gabriele), Nakamura, H. (Harunobu), Námešná, J. (Jana), Nang, E.E.K. (Ei Ei K.), Nangia, M. (Monika), Nankap, M. (Martin), Narake, S. (Sameer), Navarrete-Muñoz, E.M., Nenko, I. (Ilona), Neovius, M. (Martin), Nervi, F. (Flavio), Neuhauser, H.K. (Hannelore K.), Nguyen, N.D. (Nguyen D.), Nguyen, Q.N. (Quang Ngoc), Nieto-Martínez, R.E. (Ramfis E.), Ning, G. (Guang), Ninomiya, T. (Toshiharu), Nishtar, S. (Sania), Noale, M. (Marianna), Norat, T. (Teresa), Noto, D. (Davide), Al Nsour, M. (Mohannad), O'Reilly, D. (Dermot), Ochoa-Avilés, A.M. (Angélica M.), Oh, K. (Kyungwon), Olayan, I.H. (Iman H.), Olinto, M.T.A. (Maria Teresa Anselmo), Oltarzewski, M. (Maciej), Omar, M.A. (Mohd A.), Onat, A. (Altan), Ordunez, P. (Pedro), Ortiz, A.P. (Ana P.), Osler, M. (Merete), Osmond, C. (Clive), Ostojic, S.M. (Sergej M.), Otero, J.A. (Johanna A.), Overvad, K. (Kim), Paccaud, F.M. (Fred Michel), Padez, C. (Cristina), Pajak, A. (Andrzej), Palli, D. (Domenico), Palloni, A. (Alberto), Palmieri, L. (Luigi), Panda-Jonas, S. (Songhomitra), Panza, F. (Francesco), Parnell, W.R. (Winsome R.), Parsaeian, M. (Mahboubeh), Pednekar, M.S. (Mangesh S.), Peeters, P.H.M., Peixoto, S.V. (Sergio Viana), Pereira, A. (A.), Pérez, C.M. (Cynthia M.), Peters, A., Peykari, N. (Niloofar), Pham, S.T. (Son Thai), Pigeot, I. (Iris), Pikhart, H. (Hynek), Pilav, A. (Aida), Pilotto, A. (Alberto), Pistelli, F. (Francesco), Pitakaka, F. (Freda), Piwonska, A. (Aleksandra), Piwonski, J. (Jerzy), Plans-Rubió, P. (Pedro), Poh, B.K. (Bee Koon), Porta, M., Portegies, M.L.P. (Marileen), Poulimeneas, D. (Dimitrios), Pradeepa, R. (Rajendra), Prashant, M. (Mathur), Price, J.F. (Jackie F.), Puiu, M. (Maria), Punab, M. (Margus), Qasrawi, R.F. (Radwan F.), Qorbani, M. (Mostafa), Bao, T.Q. (Tran Quoc), Radic, I. (Ivana), Radisauskas, R. (Ricardas), Rahman, M. (Mahmudur), Raitakari, O. (Olli), Raj, M. (Manu), Rao, S.R. (Sudha Ramachandra), Ramachandran, A. (Ambady), Ramke, J. (Jacqueline), Ramos, R. (Rafel), Rampal, S. (Sanjay), Rasmussen, F. (Finn), Redón, J. (Josep), Reganit, P.F.M. (Paul Ferdinand M.), Ribeiro, R. (Robespierre), Riboli, E. (Elio), Rigo, F. (Fernando), De Wit, T.F.R. (Tobias Floris Rinke), Ritti-Dias, R.M. (Raphael M.), Rivera, J.A. (Juan A.), Robinson, S.M. (Siân), Robitaille, C. (Cynthia), Rodríguez Artalejo, F. (Fernando), Del Cristo Rodriguez-Perez, M. (María), Rodríguez-Villamizar, L.A. (Laura A.), Rojas-Martinez, R. (Rosalba), Rojroongwasinkul, N. (Nipa), Romaguera, D. (Dora), Ronkainen, K. (Kimmo), Rosengren, A. (Annika), Rouse, I. (Ian), Rubinstein, A. (Adolfo), Rühli, F.J. (Frank J.), Rui, O. (Ornelas), Ruiz-Betancourt, B.S. (Blanca Sandra), Horimoto, A.R.V.R. (Andrea R.V. Russo), Rutkowski, M. (Marcin), Sabanayagam, C. (Charumathi), Sachdev, H.S. (Harshpal S.), Saidi, O. (Olfa), Salanave, B. (Benoit), Martinez, E.S. (Eduardo Salazar), Salomaa, V. (Veikko), Salonen, J.T. (Jukka T.), Salvetti, M. (Massimo), Sánchez-Abanto, J. (Jose), Sandjaja, Sans, S. (Susana), Santos, D.A. (Diana A.), Santos, O. (Osvaldo), Dos Santos, R.N. (Renata Nunes), Santos, R. (Rute), Sardinha, L.B. (Luis B.), Sarrafzadegan, N. (Nizal), Saum, K.-U. (Kai-Uwe), Savva, S., Scazufca, M. (Marcia), Rosario, A.S. (Angelika Schaffrath), Schargrodsky, H. (Herman), Schienkiewitz, A. (Anja), Schmidt, I.M. (Ida Maria), Schneider, I.J.C. (Ione J C), Schultsz, C. (Constance), Schutte, A.E. (Aletta E.), Sein, A.A. (Aye Aye), Sen, A. (Abhijit), Senbanjo, I.O. (Idowu O.), Sepanlou, S.G. (Sadaf G), Shalnova, S.A. (Svetlana A.), Shaw, J.E., Shibuya, K. (Kenji), Shin, Y. (Youchan), Shiri, R. (Rahman), Siantar, R. (Rosalynn), Sibai, A.M. (Abla M.), Silva, A.M. (Antonio M.), Silva, D.A.S. (Diego Augusto Santos), Simon, M. (Mary), Simons, J. (Judith), Simons, L.A. (Leon A.), Sjostrom, M. (Michael), Slowikowska-Hilczer, J. (Jolanta), Slusarczyk, P. (Przemyslaw), Smeeth, L. (Liam), Smith, M.C. (Margaret C.), Snijder, M.B. (Marieke), So, H.-K. (Hung-Kwan), Sobngwi, E. (Eugène), Söderberg, S. (Stefan), Soekatri, M.Y.E. (Moesijanti Y.E.), Solfrizzi, V. (Vincenzo), Sonestedt, E. (Emily), Sørensen, T.I.A. (Thorkild), Sorić, M. (Maroje), Jérome, C.S. (Charles Sossa), Soumare, A. (Aicha), Staessen, J.A. (Jan), Starc, G. (Gregor), Stathopoulou, M.G. (Maria G.), Staub, K. (Kaspar), Stavreski, B. (Bill), Steene-Johannessen, J. (Jostein), Stehle, P. (Peter), Stein, A.D. (Aryeh D.), Stergiou, G.S. (George S.), Stessman, J. (Jochanan), Stieber, J. (Jutta), Stöckl, D. (Doris), Stocks, T. (Tanja), Stokwiszewski, J. (Jakub), Stratton, G. (Gareth), Strufaldi, M.W. (Maria Wany), Sun, C.-A. (Chien-An), Sundström, J. (Johan), Sung, Y.-T. (Yn-Tz), Sunyer, J. (Jordi), Suriyawongpaisal, P. (Paibul), Swinburn, B.A. (Boyd A.), Sy, R.G. (Rody G.), Szponar, L. (Lucjan), Tai, E.S. (E. Shyong), Tammesoo, M.L., Tamosiunas, A. (Abdonas), Tang, L. (Line), Tang, X. (Xun), Tanser, F. (Frank), Tao, Y. (Yong), Tarawneh, M. (Mohammed), Tarp, J. (Jakob), Tarqui-Mamani, C.B. (Carolina B.), Taylor, A. (Anne), Tchibindat, F. (Félicité), Thijs, L. (Lutgarde), Thuesen, L. (Leif), Tjønneland, A. (Anne), Tolonen, H.K. (Hanna K.), Tolstrup, J.S. (Janne S.), Topbas, M. (Murat), Topór-Madry, R. (Roman), Torrent, M. (Maties), Traissac, P. (Pierre), Trichopoulou, A. (Antonia), Trichopoulos, D. (Dimitrios), Trinh, O.T.H. (Oanh T.H.), Trivedi, A. (Atul), Tshepo, L. (Lechaba), Tulloch-Reid, M.K. (Marshall K.), Tuomainen, T.-P. (Tomi-Pekka), Tuomilehto, J. (Jaakko), Tynelius, P. (Per), Tzotzas, T. (Themistoklis), Tzourio, C. (Christophe), Ueda, P. (Peter), Ukoli, F.A.M. (Flora A.M.), Ulmer, H. (Hanno), Unal, B. (Belgin), Valdivia, G. (Gonzalo), Vale, S. (Susana), Valvi, D. (Damaskini), Schouw, Y.T. (Yvonne) van der, Van Herck, K. (Koen), Van Minh, H. (Hoang), Valkengoed, I. (Irene) van, Vanderschueren, D. (Dirk), Vanuzzo, D. (Diego), Vatten, L. (Lars), Vega, T. (Tomas), Velasquez-Melendez, G. (Gustavo), Veronesi, G. (Giovanni), Monique Verschuren, W.M., Viegi, G., Viet, L. (Lucie), Viikari-Juntura, E. (Eira), Vineis, P. (Paolo), Vioque, J. (Jesus), Virtanen, J.K. (Jyrki K.), Visvikis-Siest, S. (Sophie), Viswanathan, B. (Bharathi), Vollenweider, P. (Peter), Voutilainen, S. (Sari), Vrijheid, M. (Martine), Wade, A.N. (Alisha N.), Wagner, A. (Aline), Walton, J. (Janette), Mohamud, W.N.W. (Wan Nazaimoon Wan), Wang, M.-D. (Ming-Dong), Wang, Q. (Qian), Wang, Y. (Ying), Wannamethee, S.G. (Goya), Wareham, N.J. (Nick), Weerasekera, D. (Deepa), Whincup, P.H. (Peter), Widhalm, K. (Kurt), Widyahening, I.S. (Indah S.), Wiecek, A. (Andrzej), Wilks, R.J. (Rainford J.), Willeit, J. (Johann), Wojtyniak, B. (Bogdan), Wong, J.E. (Jyh Eiin), Wong, T.Y. (Tien Yin), Woo, J. (Jean), Woodward, M. (Mark), Wu, F.C. (Frederick C.), Wu, J. (JianFeng), Wu, S.L. (Shou Ling), Xu, H. (Haiquan), Xu, L. (Liang), Yamborisut, U. (Uruwan), Yan, W. (Weili), Yang, X. (Xiaoguang), Yardim, N. (Nazan), Ye, X. (Xingwang), Yiallouros, P.K. (P.), Yoshihara, A. (Akihiro), You, Q.S. (Qi Sheng), Younger-Coleman, N.O. (Novie O.), Yusoff, A.F. (Ahmad F.), Zainuddin, A.A. (Ahmad A.), Zambon, S. (Sabina), Zdrojewski, T. (T.), Zeng, Y. (Yi), Zhao, D. (Dong), Zhao, W. (Wenhua), Zheng, Y. (Yingfeng), Zhou, M. (Ming), Zhu, D. (Dan), Zimmermann, E., Cisneros, J.Z. (Julio Zuñiga), Di Cesare, M. (Mariachiara), Bentham, J. (James), Stevens, G.A. (Gretchen A.), Zhou, B. (Bin), Danaei, G. (Goodarz), Lu, Y. (Yuan), Bixby, H. (Honor), Cowan, M.J. (Melanie J.), Riley, L.M. (Leanne M.), Hajifathalian, K. (Kaveh), Fortunato, L. (Léa), Taddei, C. (Cristina), Bennett, J.E. (James E.), Ikeda, N. (Nayu), Khang, Y.-H. (Young-Ho), Kyobutungi, C. (Catherine), Laxmaiah, A. (Avula), Li, Y. (Yanping), Lin, H.-H. (Hsien-Ho), Miranda, J.J. (J. Jaime), Mostafa, A. (Aya), Turley, M.L. (Maria L.), Paciorek, C.J. (Christopher J.), Gunter, M. (Marc), Ezzati, M. (Majid), Abdeen, Z.A. (Ziad A.), Hamid, Z.A. (Zargar Abdul), Abu-Rmeileh, N.M. (Niveen M.), Acosta-Cazares, B. (Benjamin), Adams, R. (Robert), Aekplakorn, W. (Wichai), Aguilar-Salinas, C.A. (Carlos), Ahmadvand, A. (Alireza), Ahrens, W. (W.), Ali, M.M. (Mohamed M.), Alkerwi, A. (Ala'a), Alvarez-Pedrerol, M. (Mar), Aly, E. (Eman), Amouyel, P. (Philippe), Amuzu, A. (Antoinette), Andersen, L.B. (Lars Bo), Anderssen, S.A. (Sigmund A.), Andrade, D.S. (Dolores S.), Anjana, R.M. (Ranjit Mohan), Aounallah-Skhiri, H. (Hajer), Ariansen, I. (Inger), Aris, T. (Tahir), Arlappa, N. (Nimmathota), Arveiler, D. (Dominique), Assah, F.K. (Felix K.), Avdicová, M. (Mária), Azizi, J. (Joshan), Babu, B.V. (Bontha V.), Balakrishna, N. (Nagalla), Bandosz, P. (Piotr), Banegas, J.R. (José R.), Barbagallo, C.M. (Carlo M.), Barceló, A. (Alberto), Barkat, A. (Amina), Barros, M.V. (Mauro V.), Bata, I. (Iqbal), Batieha, A.M. (Anwar M.), Batista, R.L. (Rosangela L.), Baur, L.A. (Louise A.), Beaglehole, R. (Robert), Romdhane, H.B. (Habiba Ben), Benet, M. (Mikhail), Bernabe-Ortiz, A. (Antonio), Bernotiene, G. (Gailute), Bettiol, H. (Heloisa), Bhagyalaxmi, A. (Aroor), Bharadwaj, S. (Sumit), Bhargava, S.K. (Santosh K.), Bhatti, Z. (Zaid), Bhutta, Z.A. (Zulfiqar A), Bi, H. (HongSheng), Bi, Y. (Yufang), Bjerregaard, P. (Peter), Bjertness, E. (Espen), Bjertness, M.B. (Marius B.), Björkelund, C. (Cecilia), Blake, M. (Margaret), Blokstra, A. (Anneke), Bo, S. (Simona), Bobak, M. (Martin), Boddy, L.M. (Lynne M.), Boehm, B.O. (Bernhard), Boeing, H. (Heiner), Boissonnet, C.P. (Carlos P.), Bongard, V. (Vanina), Bovet, P. (Pascal), Braeckman, L. (Lutgart), Bragt, M.C.E. (Marjolijn C.E.), Brajkovich, I. (Imperia), Branca, F. (Francesco), Breckenkamp, J. (Juergen), Brenner, H. (Hermann), Brewster, L.M. (Lizzy), Brian, G.R. (Garry R.), Bruno, G. (Graziella), Bueno-De-Mesquita, H.B., Bugge, A. (Anna), Burns, C. (Con), De León, A.C. (Antonio Cabrera), Cacciottolo, J. (Joseph), Cama, T. (Tilema), Cameron, C. (Christine), Camolas, J. (José), Can, G. (Günay), Cândido, A.P.C. (Ana Paula C.), Capuano, V. (Vincenzo), Cardoso, V.C. (Viviane C.), Carvalho, M.J. (Maria J.), Casanueva, F.F. (Felipe F.), Casas, J.P. (Juan Pablo), Caserta, C.A. (Carmelo A.), Castetbon, K., Chamukuttan, S. (Snehalatha), Chan, A.W. (Angelique W.), Chan, Q. (Queenie), Chaturvedi, H.K. (Himanshu K.), Chaturvedi, N. (Nishi), Chen, C.-J. (Chien-Jen), Chen, F. (Fangfang), Chen, H. (Huashuai), Chen, S. (Shuohua), Chen, Z. (Zhengming), Cheng, C.-Y. (Ching-Yu), Chetrit, A. (Angela), Chiolero, A. (Arnaud), Chiou, S.-T. (Shu-Ti), Chirita-Emandi, A. (Adela), Cho, Y. (Yumi), Christensen, K. (Kaare), Chudek, J. (Jerzy), Cifkova, R. (Renata), Claessens, F., Clays, E. (Els), Concin, H. (Hans), Cooper, C. (Charles), Cooper, R. (Rachel), Coppinger, T.C. (Tara C.), Costanzo, S. (Simona), Cottel, D. (Dominique), Cowell, C. (Chris), Craig, C.L. (Cora L.), Crujeiras, A.B. (Ana B.), D'Arrigo, G. (Graziella), D'Orsi, E. (Eleonora), Dallongeville, J., Damasceno, A. (Albertino), Damsgaard, C.T. (Camilla T.), Dankner, R. (Rachel), Dauchet, L. (Luc), De Backer, G. (Guy), De Bacquer, D. (Dirk), De Gaetano, G. (Giovanni), De Henauw, S. (Stefaan), De Smedt, D. (Delphine), Deepa, M. (Mohan), Deev, A.D. (Alexander D.), Dehghan, A. (Abbas), Delisle, H. (Hélène), Delpeuch, F. (Francis), Dhana, K. (Klodian), Di Castelnuovo, A.F. (Augusto F.), Dias-Da-Costa, J.S. (Juvenal Soares), Diaz, A. (Alejandro), Djalalinia, S. (Shirin), Do, H.T.P. (Ha T.P.), Dobson, A.J. (Annette J.), Donfrancesco, C. (Chiara), Döring, A. (Angela), Doua, K. (Kouamelan), Drygas, W. (Wojciech), Egbagbe, E.E. (Eruke E.), Eggertsen, R. (Robert), Ekelund, U. (Ulf), El Ati, J. (Jalila), Elliott, P. (Paul), Engle-Stone, R. (Reina), Erasmus, R.T. (Rajiv T.), Erem, C. (Cihangir), Eriksen, L. (Louise), De La Peña, J.E. (Jorge Escobedo), Evans, A. (Alun), Faeh, D. (David), Fall, C.H. (Caroline H.), Farzadfar, F. (Farshad), Felix-Redondo, F.J. (Francisco J.), Ferguson, T.S. (Trevor S.), Fernández-Bergés, D. (Daniel), Ferrante, D. (Daniel), Ferrari, M. (Marika), Ferreccio, C. (Catterina), Ferrieres, J. (Jean), Finn, J.D. (Joseph D.), Fischer, K. (Krista), Flores, E.M. (Eric Monterubio), Föger, B. (Bernhard), Foo, L.H. (Leng Huat), Forslund, A.-S. (Ann-Sofie), Fortmann, S.P. (Stephen), Fouad, H.M. (Heba M.), Francis, D.K. (Damian K.), Do Carmo Franco, M. (Maria), Franco, O.H. (Oscar), Frontera, G. (Guillermo), Fuchs, F.D. (Flavio D.), Fuchs, S.C. (Sandra C.), Fujita, Y. (Yuki), Furusawa, T. (Takuro), Gaciong, Z. (Zbigniew), Gafencu, M. (Mihai), Gareta, D. (Dickman), Garnett, S.P. (Sarah P.), Gaspoz, J.-M. (Jean-Michel), Gasull, M. (Magda), Gates, L. (Louise), Geleijnse, J.M. (Marianne), Ghasemian, A. (Anoosheh), Giampaoli, S. (Simona), Gianfagna, F. (Francesco), Giovannelli, J. (Jonathan), Giwercman, A. (Aleksander), Goldsmith, R.A. (Rebecca A.), Gross, M., Rivas, J.P.G. (Juan P. González), Gorbea, M.B. (Mariano Bonet), Gottrand, F. (Frederic), Graff-Iversen, S. (Sidsel), Grafnetter, D. (Dušan), Grajda, A. (Aneta), Grammatikopoulou, M.G. (Maria G.), Gregor, R.D. (Ronald D.), Grodzicki, T. (Tomasz), Grøntved, A. (Anders), Gruden, G. (Grabriella), Grujic, V. (Vera), Gu, D. (Dongfeng), Guan, O.P. (Ong Peng), Gudnason, V. (Vilmundur), Guerrero, R. (Ramiro), Guessous, I. (Idris), Guimaraes, A.L. (Andre L.), Gulliford, M.C. (Martin C.), Gunnlaugsdottir, J. (Johanna), Guo, X.H. (Xiu H.), Guo, Y. (Yin), Gupta, P.C. (Prakash C.), Gureje, O. (Oye), Gurzkowska, B. (Beata), Gutierrez, L. (Laura), Gutzwiller, F. (Felix), Halkjær, J., Hardy, R., Kumar, R.H. (Rachakulla Hari), Hayes, A.J. (Alison J.), He, J. (Jiang), Hendriks, M.E. (Marleen), Cadena, L.H. (Leticia Hernandez), Heshmat, R. (Ramin), Hihtaniemi, I.T. (Ilpo Tapani), Ho, S.Y. (Sai Yin), Ho, S.C. (Suzanne C.), Hobbs, M. (Michael), Hofman, A. (Albert), Hormiga, C.M. (Claudia M.), Horta, B.L. (Bernardo L.), Houti, L. (Leila), Htay, T.T. (Thein Thein), Htet, A.S. (Aung Soe), Htike, M.M.T. (Maung Maung Than), Hu, Y. (Yonghua), Hussieni, A.S. (Abdullatif S.), Huu, C.N. (Chinh Nguyen), Huybrechts, I. (Inge), Hwalla, N. (Nahla), Iacoviello, L. (Licia), Iannone, A.G. (Anna G.), Ibrahim, M.M. (M. Mohsen), Ikram, M.A. (Arfan), Irazola, V. (Vilma), Islam, M. (Muhammad), Iwasaki, M. (Masanori), Jackson, R.T. (Rod T.), Jacobs, J.M. (Jeremy M.), Jafar, T.H. (Tazeen), Jamil, K.M. (Kazi M.), Jamrozik, K., Jasienska, G. (Grazyna), Jiang, C.Q. (Chao Qiang), Joffres, M. (Michel), Johansson, M. (Mattias), Jonas, J.B. (Jost B.), Jorgensen, T. (Torben), Joshi, P. (Pradeep), Juolevi, A. (Anne), Jurak, G. (Gregor), Jureša, V. (Vesna), Kaaks, R. (Rudolf), Kafatos, A. (Anthony), Kalter-Leibovici, O. (Ofra), Kapantais, E. (Efthymios), Kasaeian, A. (Amir), Katz, J. (Joanne), Kaur, P. (Prabhdeep), Kavousi, M. (Maryam), Keil, M. (Mark), Boker, L.K. (Lital Keinan), Kelishadi, R. (Roya), Kemper, H.H.C.G. (Han H.C.G.), Kengne, A.P. (Andre Pascal), Kersting, M. (Mathilde), Key, T. (Timothy), Khader, Y.S. (Yousef Saleh), Khalili, D. (Davood), Khaw, K.-T. (Kay-Tee), Khouw, I.M.S.L. (Ilse M.S.L.), Kiechl, S. (Stefan), Killewo, J. (Japhet), Kim, J. (Jeongseon), Kiyohara, Y. (Yutaka), Klimont, J. (Jeannette), Kolle, E. (Elin), Kolsteren, P. (Patrick), Korrovits, P. (Paul), Koskinen, S. (Seppo), Kouda, K. (Katsuyasu), Koziel, S. (Slawomir), Kratzer, W. (Wolfgang), Krokstad, S. (Steinar), Kromhout, D. (Daan), Kruger, H.S. (Herculina S.), Kula, K. (Krzysztof), Kulaga, Z. (Zbigniew), Kumar, R.K. (R. Krishna), Kusuma, Y.S. (Yadlapalli S.), Kuulasmaa, K. (Kari), Laamiri, F.Z. (Fatima Zahra), Laatikainen, T. (Tiina), Lachat, C. (Carl), Laid, Y. (Youcef), Lam, T.H. (Tai Hing), Landrove, O. (Orlando), Lanska, V. (Vera), Lappas, G. (Georg), Laugsand, L.E. (Lars E.), Le Nguyen Bao, K. (Khanh), Le, T.D. (Tuyen D.), Leclercq, C. (Catherine), Lee, J. (Jeannette), Lee, J. (Jeonghee), Lehtimäki, T. (Terho), Lekhraj, R. (Rampal), León-Munoz, L.M. (Luz M.), Lim, W.-Y. (Wei-Yen), Lima-Costa, M.F. (M. Fernanda), Lin, X. (Xu), Linneberg, A. (Allan), Lissner, L. (Lauren), Litwin, M. (Mieczyslaw), Liu, J. (Jing), Lorbeer, R. (Roberto), Lotufo, P.A. (Paulo A), Lozano, J.E. (José Eugenio), Luksiene, D. (Dalia), Lundqvist, A. (Annamari), Lunet, N. (Nuno), Lytsy, P. (Per), Ma, G. (Guansheng), Machi, S. (Suka), Maggi, S. (Stefania), Magliano, D.J., Makdisse, M. (Marcia), Malekzadeh, R. (Reza), Malhotra, R. (Rahul), Rao, K.M. (Kodavanti Mallikharjuna), Manios, Y., Mann, J.I. (Jim I.), Manzato, E. (Enzo), Margozzini, P. (Paula), Markey, O. (Oonagh), Marques-Vidal, P. (Pedro), Marrugat, J. (Jaume), Martin-Prevel, Y. (Yves), Martorell, R. (Reynaldo), Masoodi, S.R. (Shariq R.), Matsha, T.E. (Tandi E.), Mazur, A. (Artur), Mbanya, J.C.N. (Jean Claude N.), McFarlane, S.R. (Shelly R.), McGarvey, S.T. (Stephen T.), McKee, M. (Martin), McLachlan, S. (Stela), McLean, R.M. (Rachael M.), McNulty, B.A. (Breige A.), Md Yusof, S. (Safiah), Mediene-Benchekor, S. (Sounnia), Meirhaeghe, A. (Aline), Meisinger, C. (Christa), Mendes, L.L. (Larissa L.), Menezes, A.M.B. (Ana Maria B.), Mensink, G.B.M. (Gert B.M.), Meshram, I.I. (Indrapal I.), Metspalu, A. (Andres), Mi, J. (Jie), Michaelsen, K.F., Mikkel, K. (Kairit), Miller, J.C. (Jody C.), Miquel, J.F. (Juan Francisco), Mišigoj-Duraković, M. (Marjeta), Mohamed, M.K. (Mostafa K.), Mohammad, K. (Kazem), Mohammadifard, N. (Noushin), Mohan, V. (Viswanathan), Yusoff, M.F.M. (Muhammad Fadhli Mohd), Molbo, D. (Drude), Møller, N.C. (Niels C.), Molnár, D. (Dénes), Mondo, C.K. (Charles K.), Monterrubio, E.A. (Eric A.), Monyeki, K.D.K. (Kotsedi Daniel K.), Moreira, L.B. (Leila B.), Morejon, A. (Alain), Moreno, L.A. (Luis A.), Morgan, K. (Karen), Mortensen, E.L. (Erik Lykke), Moschonis, G., Mossakowska, M. (Malgorzata), Mota, J. (Jorge), Motlagh, M.E. (Mohammad Esmaeel), Motta, J. (Jorge), Mu, T.T. (Thet Thet), Muiesan, M.L. (Maria Lorenza), Müller-Nurasyid, M. (Martina), Murphy, N. (Neil), Mursu, J. (Jaakko), Murtagh, E.M. (Elaine M.), Musa, K.I. (Kamarul Imran), Musil, V. (Vera), Nagel, G. (Gabriele), Nakamura, H. (Harunobu), Námešná, J. (Jana), Nang, E.E.K. (Ei Ei K.), Nangia, M. (Monika), Nankap, M. (Martin), Narake, S. (Sameer), Navarrete-Muñoz, E.M., Nenko, I. (Ilona), Neovius, M. (Martin), Nervi, F. (Flavio), Neuhauser, H.K. (Hannelore K.), Nguyen, N.D. (Nguyen D.), Nguyen, Q.N. (Quang Ngoc), Nieto-Martínez, R.E. (Ramfis E.), Ning, G. (Guang), Ninomiya, T. (Toshiharu), Nishtar, S. (Sania), Noale, M. (Marianna), Norat, T. (Teresa), Noto, D. (Davide), Al Nsour, M. (Mohannad), O'Reilly, D. (Dermot), Ochoa-Avilés, A.M. (Angélica M.), Oh, K. (Kyungwon), Olayan, I.H. (Iman H.), Olinto, M.T.A. (Maria Teresa Anselmo), Oltarzewski, M. (Maciej), Omar, M.A. (Mohd A.), Onat, A. (Altan), Ordunez, P. (Pedro), Ortiz, A.P. (Ana P.), Osler, M. (Merete), Osmond, C. (Clive), Ostojic, S.M. (Sergej M.), Otero, J.A. (Johanna A.), Overvad, K. (Kim), Paccaud, F.M. (Fred Michel), Padez, C. (Cristina), Pajak, A. (Andrzej), Palli, D. (Domenico), Palloni, A. (Alberto), Palmieri, L. (Luigi), Panda-Jonas, S. (Songhomitra), Panza, F. (Francesco), Parnell, W.R. (Winsome R.), Parsaeian, M. (Mahboubeh), Pednekar, M.S. (Mangesh S.), Peeters, P.H.M., Peixoto, S.V. (Sergio Viana), Pereira, A. (A.), Pérez, C.M. (Cynthia M.), Peters, A., Peykari, N. (Niloofar), Pham, S.T. (Son Thai), Pigeot, I. (Iris), Pikhart, H. (Hynek), Pilav, A. (Aida), Pilotto, A. (Alberto), Pistelli, F. (Francesco), Pitakaka, F. (Freda), Piwonska, A. (Aleksandra), Piwonski, J. (Jerzy), Plans-Rubió, P. (Pedro), Poh, B.K. (Bee Koon), Porta, M., Portegies, M.L.P. (Marileen), Poulimeneas, D. (Dimitrios), Pradeepa, R. (Rajendra), Prashant, M. (Mathur), Price, J.F. (Jackie F.), Puiu, M. (Maria), Punab, M. (Margus), Qasrawi, R.F. (Radwan F.), Qorbani, M. (Mostafa), Bao, T.Q. (Tran Quoc), Radic, I. (Ivana), Radisauskas, R. (Ricardas), Rahman, M. (Mahmudur), Raitakari, O. (Olli), Raj, M. (Manu), Rao, S.R. (Sudha Ramachandra), Ramachandran, A. (Ambady), Ramke, J. (Jacqueline), Ramos, R. (Rafel), Rampal, S. (Sanjay), Rasmussen, F. (Finn), Redón, J. (Josep), Reganit, P.F.M. (Paul Ferdinand M.), Ribeiro, R. (Robespierre), Riboli, E. (Elio), Rigo, F. (Fernando), De Wit, T.F.R. (Tobias Floris Rinke), Ritti-Dias, R.M. (Raphael M.), Rivera, J.A. (Juan A.), Robinson, S.M. (Siân), Robitaille, C. (Cynthia), Rodríguez Artalejo, F. (Fernando), Del Cristo Rodriguez-Perez, M. (María), Rodríguez-Villamizar, L.A. (Laura A.), Rojas-Martinez, R. (Rosalba), Rojroongwasinkul, N. (Nipa), Romaguera, D. (Dora), Ronkainen, K. (Kimmo), Rosengren, A. (Annika), Rouse, I. (Ian), Rubinstein, A. (Adolfo), Rühli, F.J. (Frank J.), Rui, O. (Ornelas), Ruiz-Betancourt, B.S. (Blanca Sandra), Horimoto, A.R.V.R. (Andrea R.V. Russo), Rutkowski, M. (Marcin), Sabanayagam, C. (Charumathi), Sachdev, H.S. (Harshpal S.), Saidi, O. (Olfa), Salanave, B. (Benoit), Martinez, E.S. (Eduardo Salazar), Salomaa, V. (Veikko), Salonen, J.T. (Jukka T.), Salvetti, M. (Massimo), Sánchez-Abanto, J. (Jose), Sandjaja, Sans, S. (Susana), Santos, D.A. (Diana A.), Santos, O. (Osvaldo), Dos Santos, R.N. (Renata Nunes), Santos, R. (Rute), Sardinha, L.B. (Luis B.), Sarrafzadegan, N. (Nizal), Saum, K.-U. (Kai-Uwe), Savva, S., Scazufca, M. (Marcia), Rosario, A.S. (Angelika Schaffrath), Schargrodsky, H. (Herman), Schienkiewitz, A. (Anja), Schmidt, I.M. (Ida Maria), Schneider, I.J.C. (Ione J C), Schultsz, C. (Constance), Schutte, A.E. (Aletta E.), Sein, A.A. (Aye Aye), Sen, A. (Abhijit), Senbanjo, I.O. (Idowu O.), Sepanlou, S.G. (Sadaf G), Shalnova, S.A. (Svetlana A.), Shaw, J.E., Shibuya, K. (Kenji), Shin, Y. (Youchan), Shiri, R. (Rahman), Siantar, R. (Rosalynn), Sibai, A.M. (Abla M.), Silva, A.M. (Antonio M.), Silva, D.A.S. (Diego Augusto Santos), Simon, M. (Mary), Simons, J. (Judith), Simons, L.A. (Leon A.), Sjostrom, M. (Michael), Slowikowska-Hilczer, J. (Jolanta), Slusarczyk, P. (Przemyslaw), Smeeth, L. (Liam), Smith, M.C. (Margaret C.), Snijder, M.B. (Marieke), So, H.-K. (Hung-Kwan), Sobngwi, E. (Eugène), Söderberg, S. (Stefan), Soekatri, M.Y.E. (Moesijanti Y.E.), Solfrizzi, V. (Vincenzo), Sonestedt, E. (Emily), Sørensen, T.I.A. (Thorkild), Sorić, M. (Maroje), Jérome, C.S. (Charles Sossa), Soumare, A. (Aicha), Staessen, J.A. (Jan), Starc, G. (Gregor), Stathopoulou, M.G. (Maria G.), Staub, K. (Kaspar), Stavreski, B. (Bill), Steene-Johannessen, J. (Jostein), Stehle, P. (Peter), Stein, A.D. (Aryeh D.), Stergiou, G.S. (George S.), Stessman, J. (Jochanan), Stieber, J. (Jutta), Stöckl, D. (Doris), Stocks, T. (Tanja), Stokwiszewski, J. (Jakub), Stratton, G. (Gareth), Strufaldi, M.W. (Maria Wany), Sun, C.-A. (Chien-An), Sundström, J. (Johan), Sung, Y.-T. (Yn-Tz), Sunyer, J. (Jordi), Suriyawongpaisal, P. (Paibul), Swinburn, B.A. (Boyd A.), Sy, R.G. (Rody G.), Szponar, L. (Lucjan), Tai, E.S. (E. Shyong), Tammesoo, M.L., Tamosiunas, A. (Abdonas), Tang, L. (Line), Tang, X. (Xun), Tanser, F. (Frank), Tao, Y. (Yong), Tarawneh, M. (Mohammed), Tarp, J. (Jakob), Tarqui-Mamani, C.B. (Carolina B.), Taylor, A. (Anne), Tchibindat, F. (Félicité), Thijs, L. (Lutgarde), Thuesen, L. (Leif), Tjønneland, A. (Anne), Tolonen, H.K. (Hanna K.), Tolstrup, J.S. (Janne S.), Topbas, M. (Murat), Topór-Madry, R. (Roman), Torrent, M. (Maties), Traissac, P. (Pierre), Trichopoulou, A. (Antonia), Trichopoulos, D. (Dimitrios), Trinh, O.T.H. (Oanh T.H.), Trivedi, A. (Atul), Tshepo, L. (Lechaba), Tulloch-Reid, M.K. (Marshall K.), Tuomainen, T.-P. (Tomi-Pekka), Tuomilehto, J. (Jaakko), Tynelius, P. (Per), Tzotzas, T. (Themistoklis), Tzourio, C. (Christophe), Ueda, P. (Peter), Ukoli, F.A.M. (Flora A.M.), Ulmer, H. (Hanno), Unal, B. (Belgin), Valdivia, G. (Gonzalo), Vale, S. (Susana), Valvi, D. (Damaskini), Schouw, Y.T. (Yvonne) van der, Van Herck, K. (Koen), Van Minh, H. (Hoang), Valkengoed, I. (Irene) van, Vanderschueren, D. (Dirk), Vanuzzo, D. (Diego), Vatten, L. (Lars), Vega, T. (Tomas), Velasquez-Melendez, G. (Gustavo), Veronesi, G. (Giovanni), Monique Verschuren, W.M., Viegi, G., Viet, L. (Lucie), Viikari-Juntura, E. (Eira), Vineis, P. (Paolo), Vioque, J. (Jesus), Virtanen, J.K. (Jyrki K.), Visvikis-Siest, S. (Sophie), Viswanathan, B. (Bharathi), Vollenweider, P. (Peter), Voutilainen, S. (Sari), Vrijheid, M. (Martine), Wade, A.N. (Alisha N.), Wagner, A. (Aline), Walton, J. (Janette), Mohamud, W.N.W. (Wan Nazaimoon Wan), Wang, M.-D. (Ming-Dong), Wang, Q. (Qian), Wang, Y. (Ying), Wannamethee, S.G. (Goya), Wareham, N.J. (Nick), Weerasekera, D. (Deepa), Whincup, P.H. (Peter), Widhalm, K. (Kurt), Widyahening, I.S. (Indah S.), Wiecek, A. (Andrzej), Wilks, R.J. (Rainford J.), Willeit, J. (Johann), Wojtyniak, B. (Bogdan), Wong, J.E. (Jyh Eiin), Wong, T.Y. (Tien Yin), Woo, J. (Jean), Woodward, M. (Mark), Wu, F.C. (Frederick C.), Wu, J. (JianFeng), Wu, S.L. (Shou Ling), Xu, H. (Haiquan), Xu, L. (Liang), Yamborisut, U. (Uruwan), Yan, W. (Weili), Yang, X. (Xiaoguang), Yardim, N. (Nazan), Ye, X. (Xingwang), Yiallouros, P.K. (P.), Yoshihara, A. (Akihiro), You, Q.S. (Qi Sheng), Younger-Coleman, N.O. (Novie O.), Yusoff, A.F. (Ahmad F.), Zainuddin, A.A. (Ahmad A.), Zambon, S. (Sabina), Zdrojewski, T. (T.), Zeng, Y. (Yi), Zhao, D. (Dong), Zhao, W. (Wenhua), Zheng, Y. (Yingfeng), Zhou, M. (Ming), Zhu, D. (Dan), Zimmermann, E., and Cisneros, J.Z. (Julio Zuñiga)
Abstract: Copyright
Published: 2016
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15. Genetic sharing with cardiovascular disease risk factors and diabetes reveals novel bone mineral density loci

Author: Reppe, S. (Sjur), Wang, Y. (Yunpeng), Thompson, W.K. (Wesley K.), McEvoy, L.K. (Linda K.), Schork, N.J. (Nicholas), Zuber, V. (Verena), Leblanc, M. (Marissa), Bettella, F. (Francesco), Mills, I.G. (Ian G.), Desikan, R.S. (Rahul S.), Djurovic, S. (Srdjan), Gautvik, K.M. (Kaare), Dale, A.M. (Anders), Andreassen, O.A. (Ole), Estrada Gil, K. (Karol), Styrkarsdottir, U. (Unnur), Evangelou, E. (Evangelos), Hsu, Y.-H. (Yi-Hsiang), Duncan, E.L. (Emma), Ntzani, E.E. (Evangelia), Oei, L. (Ling), Albagha, O.M.E. (Omar M.), Amin, N. (Najaf), Kemp, J.P. (John), Koller, D.L. (Daniel), Li, G. (Guo), Liu, C.-T. (Ching-Ti), Minster, R.L. (Ryan), Moayyeri, A. (Alireza), Vandenput, L. (Liesbeth), Willner, D. (Dana), Xiao, S.-M. (Su-Mei), Yerges-Armstrong, L.M. (Laura), Zheng, H.-F. (Hou-Feng), Alonso, N. (Nerea), Eriksson, J. (Joel), Kammerer, C.M. (Candace), Kaptoge, S. (Stephen), Leo, P.J. (Paul), Thorleifsson, G. (Gudmar), Wilson, S.G. (Scott), Wilson, J.F. (James F), Aalto, V. (Ville), Alen, M. (Markku), Aragaki, A.K. (Aaron), Aspelund, T. (Thor), Center, J.R. (Jacqueline), Dailiana, Z. (Zoe), Duggan, C., Garcia, M. (Melissa), Garcia-Giralt, N. (Natàlia), Giroux, S. (Sylvie), Hallmans, G. (Göran), Hocking, L.J. (Lynne), Husted, L.B. (Lise Bjerre), Jameson, K. (Karen), Khusainova, R. (Rita), Kim, G.S. (Ghi Su), Kooperberg, C. (Charles), Koromila, T. (Theodora), Kruk, M. (Marcin), Laaksonen, M. (Marika), Lacroix, A.Z. (Andrea Z.), Lee, S.H. (Seung Hun), Leung, P.C. (Ping C.), Lewis, J.R. (Joshua), Masi, L. (Laura), Mencej-Bedrac, S. (Simona), Nguyen, T.V. (Tuan), Nogues, X. (Xavier), Patel, M.S. (Millan), Prezelj, J. (Janez), Rose, L.M. (Lynda), Scollen, S. (Serena), Siggeirsdottir, K. (Kristin), Smith, A.V. (Davey), Svensson, O. (Olle), Trompet, S. (Stella), Trummer, O. (Olivia), Schoor, N.M. (Natasja) van, Woo, J. (Jean), Zhu, K. (Kun), Balcells, S. (Susana), Brandi, M.L., Buckley, B.M. (Brendan M.), Cheng, S. (Sulin), Christiansen, C., Cooper, C. (Charles), Dedoussis, G.V. (George), Ford, I. (Ian), Frost, M. (Morten), Goltzman, D. (David), González-Macías, J. (Jesús), Kähönen, M. (Mika), Karlsson, M. (Magnus), Khusnutdinova, E.K. (Elza), Koh, J.-M. (Jung-Min), Kollia, P. (Panagoula), Langdahl, B.L. (Bente), Leslie, W.D. (William D.), Lips, P. (Paul), Ljunggren, O. (Östen), Lorenc, R. (Roman), Marc, J. (Janja), Mellström, D. (Dan), Obermayer-Pietsch, B. (Barbara), Olmos, D. (David), Pettersson-Kymmer, U. (Ulrika), Reid, D.M. (David), Riancho, J.A. (José), Ridker, P.M. (Paul), Rousseau, M.F. (Francois), Slagboom, P.E. (Eline), Tang, N.L.S. (Nelson L.S.), Urreizti, R. (Roser), Van Hul, W. (Wim), Viikari, J. (Jorma), Zarrabeitia, M.T. (María), Aulchenko, Y.S. (Yurii), Castaño Betancourt, M.C. (Martha), Grundberg, E. (Elin), Herrera, L. (Lizbeth), Ingvarsson, T. (Torvaldur), Johannsdottir, H. (Hrefna), Kwan, T. (Tony), Li, R. (Rui), Luben, R.N. (Robert), Medina-Gomez, M.C. (Carolina), Palsson, S.T. (Stefan Th), Rotter, J.I. (Jerome I.), Sigurdsson, G. (Gunnar), Meurs, J.B.J. (Joyce) van, Verlaan, D.J. (Dominique), Williams, F.M. (Frances), Wood, A.R. (Andrew), Zhou, Y. (Yanhua), Pastinen, T. (Tomi), Raychaudhuri, S. (Soumya), Cauley, J.A. (Jane), Chasman, D.I. (Daniel), Clark, G.R. (Graeme), Cummings, S.R. (Steven R.), Danoy, P. (Patrick), Dennison, E.M. (Elaine), Eastell, R. (Richard), Eisman, J.A. (John), Gudnason, V. (Vilmundur), Hofman, A. (Albert), Jackson, R.D. (Rebecca), Jones, G. (Graeme), Jukema, J.W. (Jan Wouter), Khaw, K.T., Lehtimäki, T. (Terho), Liu, Y. (YongMei), Lorentzon, M. (Mattias), McCloskey, E.V. (Eugene), Mitchell, B.D. (Braxton), Nandakumar, K. (Kannabiran), Nicholson, G.C. (Geoffrey), Oostra, B.A. (Ben), Peacock, M. (Munro), Pols, H.A.P. (Huib), Prince, R.L. (Richard), Raitakari, O. (Olli), Reid, I.R. (Ian), Robbins, J. (John), Sambrook, P.N. (Philip), Sham, P.C. (Pak Chung), Shuldiner, A.R. (Alan), Tylavsky, F.A. (Frances), Duijn, C.M. (Cornelia) van, Wareham, N.J. (Nicholas J.), Cupples, L.A. (Adrienne), Econs, M.J. (Michael), Evans, D.M. (David), Harris, T.B. (Tamara B.), Kung, A.W.C. (Annie Wai Chee), Psaty, B.M. (Bruce), Reeve, J. (Jonathan), Spector, T.D. (Timothy), Streeten, E.A. (Elizabeth), Zillikens, M.C. (Carola), Thorsteinsdottir, U. (Unnur), Ohlsson, C. (Claes), Karasik, D. (David), Richards, J.B. (Brent), Brown, M.A. (Matthew), Zwart, J-A. (John-Anker), Uitterlinden, A.G. (André), Ralston, S.H. (Stuart), Ioannidis, J.P.A. (John P.A.), Kiel, D.P. (Douglas P.), Rivadeneira Ramirez, F. (Fernando), Reppe, S. (Sjur), Wang, Y. (Yunpeng), Thompson, W.K. (Wesley K.), McEvoy, L.K. (Linda K.), Schork, N.J. (Nicholas), Zuber, V. (Verena), Leblanc, M. (Marissa), Bettella, F. (Francesco), Mills, I.G. (Ian G.), Desikan, R.S. (Rahul S.), Djurovic, S. (Srdjan), Gautvik, K.M. (Kaare), Dale, A.M. (Anders), Andreassen, O.A. (Ole), Estrada Gil, K. (Karol), Styrkarsdottir, U. (Unnur), Evangelou, E. (Evangelos), Hsu, Y.-H. (Yi-Hsiang), Duncan, E.L. (Emma), Ntzani, E.E. (Evangelia), Oei, L. (Ling), Albagha, O.M.E. (Omar M.), Amin, N. (Najaf), Kemp, J.P. (John), Koller, D.L. (Daniel), Li, G. (Guo), Liu, C.-T. (Ching-Ti), Minster, R.L. (Ryan), Moayyeri, A. (Alireza), Vandenput, L. (Liesbeth), Willner, D. (Dana), Xiao, S.-M. (Su-Mei), Yerges-Armstrong, L.M. (Laura), Zheng, H.-F. (Hou-Feng), Alonso, N. (Nerea), Eriksson, J. (Joel), Kammerer, C.M. (Candace), Kaptoge, S. (Stephen), Leo, P.J. (Paul), Thorleifsson, G. (Gudmar), Wilson, S.G. (Scott), Wilson, J.F. (James F), Aalto, V. (Ville), Alen, M. (Markku), Aragaki, A.K. (Aaron), Aspelund, T. (Thor), Center, J.R. (Jacqueline), Dailiana, Z. (Zoe), Duggan, C., Garcia, M. (Melissa), Garcia-Giralt, N. (Natàlia), Giroux, S. (Sylvie), Hallmans, G. (Göran), Hocking, L.J. (Lynne), Husted, L.B. (Lise Bjerre), Jameson, K. (Karen), Khusainova, R. (Rita), Kim, G.S. (Ghi Su), Kooperberg, C. (Charles), Koromila, T. (Theodora), Kruk, M. (Marcin), Laaksonen, M. (Marika), Lacroix, A.Z. (Andrea Z.), Lee, S.H. (Seung Hun), Leung, P.C. (Ping C.), Lewis, J.R. (Joshua), Masi, L. (Laura), Mencej-Bedrac, S. (Simona), Nguyen, T.V. (Tuan), Nogues, X. (Xavier), Patel, M.S. (Millan), Prezelj, J. (Janez), Rose, L.M. (Lynda), Scollen, S. (Serena), Siggeirsdottir, K. (Kristin), Smith, A.V. (Davey), Svensson, O. (Olle), Trompet, S. (Stella), Trummer, O. (Olivia), Schoor, N.M. (Natasja) van, Woo, J. (Jean), Zhu, K. (Kun), Balcells, S. (Susana), Brandi, M.L., Buckley, B.M. (Brendan M.), Cheng, S. (Sulin), Christiansen, C., Cooper, C. (Charles), Dedoussis, G.V. (George), Ford, I. (Ian), Frost, M. (Morten), Goltzman, D. (David), González-Macías, J. (Jesús), Kähönen, M. (Mika), Karlsson, M. (Magnus), Khusnutdinova, E.K. (Elza), Koh, J.-M. (Jung-Min), Kollia, P. (Panagoula), Langdahl, B.L. (Bente), Leslie, W.D. (William D.), Lips, P. (Paul), Ljunggren, O. (Östen), Lorenc, R. (Roman), Marc, J. (Janja), Mellström, D. (Dan), Obermayer-Pietsch, B. (Barbara), Olmos, D. (David), Pettersson-Kymmer, U. (Ulrika), Reid, D.M. (David), Riancho, J.A. (José), Ridker, P.M. (Paul), Rousseau, M.F. (Francois), Slagboom, P.E. (Eline), Tang, N.L.S. (Nelson L.S.), Urreizti, R. (Roser), Van Hul, W. (Wim), Viikari, J. (Jorma), Zarrabeitia, M.T. (María), Aulchenko, Y.S. (Yurii), Castaño Betancourt, M.C. (Martha), Grundberg, E. (Elin), Herrera, L. (Lizbeth), Ingvarsson, T. (Torvaldur), Johannsdottir, H. (Hrefna), Kwan, T. (Tony), Li, R. (Rui), Luben, R.N. (Robert), Medina-Gomez, M.C. (Carolina), Palsson, S.T. (Stefan Th), Rotter, J.I. (Jerome I.), Sigurdsson, G. (Gunnar), Meurs, J.B.J. (Joyce) van, Verlaan, D.J. (Dominique), Williams, F.M. (Frances), Wood, A.R. (Andrew), Zhou, Y. (Yanhua), Pastinen, T. (Tomi), Raychaudhuri, S. (Soumya), Cauley, J.A. (Jane), Chasman, D.I. (Daniel), Clark, G.R. (Graeme), Cummings, S.R. (Steven R.), Danoy, P. (Patrick), Dennison, E.M. (Elaine), Eastell, R. (Richard), Eisman, J.A. (John), Gudnason, V. (Vilmundur), Hofman, A. (Albert), Jackson, R.D. (Rebecca), Jones, G. (Graeme), Jukema, J.W. (Jan Wouter), Khaw, K.T., Lehtimäki, T. (Terho), Liu, Y. (YongMei), Lorentzon, M. (Mattias), McCloskey, E.V. (Eugene), Mitchell, B.D. (Braxton), Nandakumar, K. (Kannabiran), Nicholson, G.C. (Geoffrey), Oostra, B.A. (Ben), Peacock, M. (Munro), Pols, H.A.P. (Huib), Prince, R.L. (Richard), Raitakari, O. (Olli), Reid, I.R. (Ian), Robbins, J. (John), Sambrook, P.N. (Philip), Sham, P.C. (Pak Chung), Shuldiner, A.R. (Alan), Tylavsky, F.A. (Frances), Duijn, C.M. (Cornelia) van, Wareham, N.J. (Nicholas J.), Cupples, L.A. (Adrienne), Econs, M.J. (Michael), Evans, D.M. (David), Harris, T.B. (Tamara B.), Kung, A.W.C. (Annie Wai Chee), Psaty, B.M. (Bruce), Reeve, J. (Jonathan), Spector, T.D. (Timothy), Streeten, E.A. (Elizabeth), Zillikens, M.C. (Carola), Thorsteinsdottir, U. (Unnur), Ohlsson, C. (Claes), Karasik, D. (David), Richards, J.B. (Brent), Brown, M.A. (Matthew), Zwart, J-A. (John-Anker), Uitterlinden, A.G. (André), Ralston, S.H. (Stuart), Ioannidis, J.P.A. (John P.A.), Kiel, D.P. (Douglas P.), and Rivadeneira Ramirez, F. (Fernando)
Abstract: Bone Mineral Density (BMD) is a highly heritable trait, but genome-wide association studies have identified few genetic risk factors. Epidemiological studies suggest associations between BMD and several traits and diseases, but the nature of the suggestive comorbidity is still unknown. We used a novel genetic pleiotropy-informed conditional False Discovery Rate (FDR) method to identify single nucleotide polymorphisms (SNPs) associated with BMD by leveraging cardiovascular disease (CVD) associated disorders and metabolic traits. By conditioning on SNPs associated with the CVD-related phenotypes, type 1 diabetes, type 2 diabetes, systolic blood pressure, diastolic blood pressure, high density lipoprotein, low density lipoprotein, triglycerides and waist hip ratio, we identified 65 novel independent BMD loci (26 with femoral neck BMD and 47 with lumbar spine BMD) at conditional FDR < 0.01. Many of the loci were confirmed in genetic expression studies. Genes validated at the mRNA levels were characteristic for the osteoblast/osteocyte lineage, Wnt signaling pathway and bone metabolism. The results provide new insight into genetic mechanisms of variability in BMD, and a better understanding of the genetic underpinnings of clinical comorbidity.
Published: 2015
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16. Global, regional, and national incidence and mortality for HIV, tuberculosis, and malaria during 1990-2013: a systematic analysis for the Global Burden of Disease Study 2013

Author: Murray, C.J.L. (Christopher), Ortblad, K.F. (Katrina F), Guinovart, C. (Caterina), Lim, S.S. (Stephen), Wolock, T.M. (Timothy M), Roberts, D.A. (D Allen), Dansereau, E.A. (Emily A), Graetz, N. (Nicholas), Barber, R.M. (Ryan), Brown, J.C. (Jonathan C), Wang, H. (Haidong), Duber, H.C. (Herbert C), Naghavi, M. (Morteza), Dicker, D. (Daniel), Dandona, L. (Lalit), Salomon, J.A. (Joshua), Heuton, K.R. (Kyle R), Foreman, K. (Kyle), Phillips, D.E. (David E), Fleming, T.D. (Thomas D), Flaxman, A.D. (Abraham D), Phillips, B.K. (Bryan K), Johnson, E.M. (Elizabeth), Coggeshall, M.S. (Megan S), Abd-Allah, F. (Foad), Abera, S.F. (Semaw Ferede), Abraham, J.P. (Jerry), Abubakar, I. (Ibrahim), Abu-Raddad, L.J. (Laith J), Abu-Rmeileh, N.M. (Niveen Me), Achoki, T. (Tom), Adeyemo, A. (Adebowale), Adou, A.K. (Arsène Kouablan), Adsuar, J.C. (José C), Agardh, E.E. (Emilie Elisabet), Akena, D. (Dickens), Al Kahbouri, M.J. (Mazin J), Alasfoor, D. (Deena), Albittar, M.I. (Mohammed I), Alcalá-Cerra, G. (Gabriel), Alegretti, M.A. (Miguel Angel), Alemu, G. (Getnet), Alfonso-Cristancho, R. (Rafael), Alhabib, S. (Samia), Ali, R. (Raghib), Alla, F. (Francois), Allen, P.J. (Peter), Alsharif, U. (Ubai), Alvarez, E. (Elena), Alvis-Guzman, N. (Nelson), Amankwaa, A.A. (Adansi A), Amare, A.T. (Azmeraw T), Amini, H. (Hassan), Ammar, K.A., Anderson, B.O. (Benjamin), Antonio, C.A.T. (Carl Abelardo T), Anwari, P. (Palwasha), Ärnlöv, J. (Johan), Arsenijevic, V.S.A. (Valentina S Arsic), Artaman, A. (Ali), Asghar, R.J. (Rana J), Assadi, R. (Reza), Atkins, L.S. (Lydia S), Badawi, A.F. (Alaa), Banerjee, A. (Amitava), Basu, S. (Saonli), Beardsley, J. (Justin), Bekele, T. (Tolesa), Bell, M.L. (Michelle Lee), Bernabe, E. (Eduardo), Beyene, T.J. (Tariku Jibat), Bhala, N. (Neeraj), Bhalla, P.L. (Pankaj), Bhutta, Z.A. (Zulfiqar A), Abdulhak, A.B. (Aref Bin), Binagwaho, A. (Agnes), Blore, J.D. (Jed D), Bose, D. (Dipan), Brainin, M. (Michael), Breitborde, N. (Nicholas), Castañeda-Orjuela, C.A. (Carlos A), Catalá-López, F. (Ferrán), Chadha, D., Chang, J.-C. (Jung-Chen), Chiang, Y.T., Chuang, T.-W. (Ting-Wu), Colomar, M. (Mercedes), Cooper Jr., L.T. (Leslie Trumbull), Cooper, C. (Charles), Courville, K.J. (Karen J), Cowie, M.R. (Martin R.), Criqui, M. (Michael), Dandona, R. (Rakhi), Dayama, A. (Anand), Leo, D. (Diego) de, Degenhardt, F., Del Pozo-Cruz, B. (Borja), Deribe, K. (Kebede), Des Jarlais, D.C. (Don C), Dessalegn, M. (Muluken), Dharmaratne, S.D. (Samath D), Dilmen, U. (Uǧur), Ding, E.L. (Eric), Driscoll, J.M., Durrani, Z., Ellenbogen, R.G. (Richard G), Ermakov, S. (Sergey), Esteghamati, A. (Alireza), Faraon, E.J.A. (Emerito Jose A), Farzadfar, F. (Farshad), Fereshtehnejad, S.-M. (Seyed-Mohammad), Fijabi, D.O. (Daniel Obadare), Forouzanfar, M.H. (Mohammad H), Fra.Paleo, U. (Urbano), Gaffikin, L. (Lynne), Gamkrelidze, A. (Amiran), Gankpé, F.G. (Fortuné Gbètoho), Geleijnse, J.M. (Marianne), Gessner, B.D. (Bradford D), Gibney, K.B. (Katherine B), Ginawi, I.A.M. (Ibrahim Abdelmageem Mohamed), Glaser, E.L. (Elizabeth L), Gona, P. (Philimon), Goto, A. (Akimoto), Gouda, H.N. (Hebe N), Gugnani, H.C. (Harish Chander), Gupta, R. (Rajeev), Hafezi-Nejad, N. (Nima), Hamadeh, R.R. (Randah Ribhi), Hammami, M. (Mouhanad), Hankey, G.J. (Graeme), Harb, H.L. (Hilda L), Haro, J.M. (Josep Maria), Havmoeller, R. (Rasmus), Hay, S.I. (Simon I), Hedayati, M.T. (Mohammad T), Pi, I.B.H. (Ileana B Heredia), Hoek, H.W. (Hans), Hornberger, J.C. (John C), Hosgood, H.D. (H Dean), Hotez, P.J. (Peter), Hoy, D.G. (Damian G), Huang, J. (Jian), Iburg, K.M. (Kim M), Idrisov, B.T. (Bulat T), Innos, K. (Kaire), Jacobsen, K.H. (Kathryn H), Jeemon, P. (Panniyammakal), Jensen, P.N. (Paul N), Jha, V. (Vivekanand), Jiang, G. (Guohong), Jonas, J.B., Juel, K. (Knud), Kan, H. (Haidong), Kankindi, I. (Ida), Karam, V. (Vincent), Karch, F. (Francois), Karema, C.K. (Corine Kakizi), Kaul, A. (Anil), Kawakami, N. (Norito), Kazi, D.S. (Dhruv S), Kemp, A.H. (Andrew H), Kengne, A.P. (Andre Pascal), Keren, A. (Andre), Kereselidze, M. (Maia), Khader, Y.S. (Yousef Saleh), Khalifa, S.E.A.H. (Shams Eldin Ali Hassan), Khan, E.A. (Ejaz Ahmed), Khang, Y.-H. (Young-Ho), Khonelidze, I. (Irma), Kinfu, Y. (Yohannes), Kinge, J.M. (Jonas M), Knibbs, L. (Luke), Kokubo, Y. (Yoshihiro), Kosen, S. (Soewarta), Defo, B.K. (Barthelemy Kuate), Kulkarni, V.S. (Veena S), Kulkarni, C. (Chanda), Kumar, K. (Kuldeep), Kumar, R.B. (Ravi B), Kumar, G.A. (G Anil), Kwan, G.F. (Gene F), Lai, T. (Taavi), Balaji, A.L. (Arjun Lakshmana), Lam, H. (Hilton), Lan, Q. (Qing), Lansingh, V.C. (Van C), Larson, H.J. (Heidi J), Larsson, A. (Anders), Lee, J.-T. (Jong-Tae), Leigh, P.N. (Nigel), Leinsalu, M. (Mall), Leung, R. (Ricky), Li, Y. (Yichong), Li, Y. (Yongmei), Lima, G.M.F. (Graça Maria Ferreira) de, Lin, H.-H. (Hsien-Ho), Lipshultz, S.E. (Steven), Liu, S. (Simin), Liu, Y. (Yang), Lloyd, B.K. (Belinda K), Lotufo, P.A. (Paulo A), Machado, V.M.P. (Vasco Manuel Pedro), Maclachlan, J.H. (Jennifer H), Magis-Rodriguez, C. (Carlos), Majdan, M. (Marek), Mapoma, C.C. (Christopher Chabila), Marcenes, W. (Wagner), Marzan, M.B. (Melvin Barrientos), Masci, J.R. (Joseph R), Mashal, R., Mason-Jones, A.J. (Amanda J), Mayosi, B.M. (Bongani), Mazorodze, T.T. (Tasara T), Mckay, M.J. (Michael), Meaney, M.J., Mehndiratta, M.M. (Man Mohan), Mejia-Rodriguez, F. (Fabiola), Melaku, Y.A. (Yohannes Adama), Memish, Z.A. (Ziad), Mendoza, W. (Walter), Miller, T.R. (Ted R), Mills, E.J. (Edward J), Mohammad, K.A. (Karzan Abdulmuhsin), Mokdad, A.H. (Ali H), Mola, G.L. (Glen Liddell), Monasta, L. (Lorenzo), Montico, M. (Marcella), Moore, A.R. (Ami R), Mori, R. (Riccardo), Moturi, W.N. (Wilkister Nyaora), Mukaigawara, M. (Mitsuru), Murthy, A.C. (Adeline C.), Naheed, A. (Aliya), Naidoo, K.S. (Kovin S), Naldi, L. (Lucia), Nangia, M. (Monika), Narayan, K.M.V. (Venkat), Nash, J.H.E. (John), Nejjari, C. (Chakib), Nelson, R.D. (Robert), Neupane, S.P. (Sudan Prasad), Newton, C. (Cameron), Ng, M. (Marie), Nisar, M.I. (Muhammad Imran), Nolte, S. (Sandra), Norheim, O.F. (Ole F), Nowaseb, V. (Vincent), Nyakarahuka, L. (Luke), Oh, I.-H. (In-Hwan), Ohkubo, T. (Takayoshi), Olusanya, B.O. (Bolajoko O), Omer, S.B. (Saad B), Opio, J.N. (John Nelson), Orisakwe, O.E. (Orish Ebere), Pandian, N.G. (Natesa), Papachristou, C., Caicedo, M.S. (Marco), Patten, J., Paul, V.K. (Vinod K), Pavlin, B.I. (Boris Igor), Pearce, N. (Neil), Pereira, D.M. (David M), Pervaiz, Z. (Zahid), Pesudovs, K. (Konrad), Petzold, M. (Max), Pourmalek, F. (Farshad), Qato, D. (Dima), Quezada, A.D. (Amado D), Quistberg, D.A. (D Alex), Rafay, A. (Anwar), Rahimi, K. (Kazem), Rahimi-Movaghar, V. (Vafa), Rahman, S.U. (Sajjad Ur), Raju, M. (Murugesan), Rana, S.M. (Saleem M), Razavi, H. (Homie), Reilly, R.Q. (Robert Quentin), Remuzzi, G. (Giuseppe), Richardus, J.H. (Jan Hendrik), Ronfani, L. (Luca), Roy, N. (Nadine) van, Sabin, M.L. (Miriam Lewis), Saeedi, M.Y. (Mohammad Yahya), Sahraian, M.A. (Mohammad Ali), Samonte, G.M.J. (Genesis May J), Sawhney, M.S. (Monika), Schneider, I.J.C. (Ione J C), Schwebel, D.C. (David C), Seedat, S. (Soraya), Sepanlou, S.G. (Sadaf G), Servan-Mori, E.E. (Edson E), Sheikhbahaei, S. (Sara), Shibuya, K. (Kenji), Shin, H.H. (Hwashin Hyun), Shiue, I. (Ivy), Shivakoti, R. (Rupak), Sigfusdottir, I.D. (Inga Dora), Silberberg, D.H. (Donald H), Silva, A.P. (Andrea P), Simard, J. (Jacques), Singh, J.A. (Jasvinder), Skirbekk, V. (Vegard), Sliwa, K. (Karen), Soneji, S. (Samir), Soshnikov, S.S. (Sergey S), Sreeramareddy, C.T. (Chandrashekhar T), Stathopoulou, V.K. (Vasiliki Kalliopi), Stroumpoulis, K. (Konstantinos), Swaminathan, S., Sykes, B.C. (Bryan), Tabb, K.M. (Karen M), Talongwa, R.T. (Roberto Tchio), Tenkorang, E.Y. (Eric Yeboah), Terkawi, A.S. (Abdullah Sulieman), Thomson, A.J. (Alan J), Thorne-Lyman, A.L. (Andrew L), Towbin, J.A. (Jeffrey A), Traebert, J. (Jefferson), Tran, B.X. (Bach X), Dimbuene, Z.T. (Zacharie Tsala), Tsilimbaris, M. (Miltiadis), Uchendu, U.S. (Uche S), Ukwaja, K.N. (Kingsley N), Vallely, S.R. (Stephen), Vasankari, T.J. (Tommi J), Venketasubramanian, N. (Narayanaswamy), Violante, F.S. (Francesco S), Vlassov, V.V. (Vasiliy Victorovich), Waller, P. (Patrick), Wallin, M.T. (Mitchell T), Wang, L. (Linhong), Wang, S.X., Wang, Y. (Yanping), Weichenthal, S. (Scott), Weiderpass, E. (Elisabete), Weintraub, R.G. (Robert G), Westerman, R. (Ronny), White, R.G. (Richard), Wilkinson, J.D. (James D), Williams, T.N. (Thomas Neil), Woldeyohannes, S.M. (Solomon Meseret), Wong, J.B. (John), Xu, G. (Gelin), Yang, Y.C. (Yang C), Yano, K.-I., Yip, P. (Paul), Yonemoto, N. (Naohiro), Yoon, S.-J. (Seok-Jun), Younis, M. (Mustafa), Yu, C. (Chuanhua), Jin, K.Y. (Kim Yun), El Sayed Zaki, M. (Maysaa), Zhao, Y. (Yong), Zheng, Y. (Yuhui), Balakrishnan, K. (Kalpana), Zhou, M. (Ming), Zhu, J. (Jun), Zou, X.N. (Xiao Nong), Lopez, A.D. (Alan D), Vos, T. (Theo), Murray, C.J.L. (Christopher), Ortblad, K.F. (Katrina F), Guinovart, C. (Caterina), Lim, S.S. (Stephen), Wolock, T.M. (Timothy M), Roberts, D.A. (D Allen), Dansereau, E.A. (Emily A), Graetz, N. (Nicholas), Barber, R.M. (Ryan), Brown, J.C. (Jonathan C), Wang, H. (Haidong), Duber, H.C. (Herbert C), Naghavi, M. (Morteza), Dicker, D. (Daniel), Dandona, L. (Lalit), Salomon, J.A. (Joshua), Heuton, K.R. (Kyle R), Foreman, K. (Kyle), Phillips, D.E. (David E), Fleming, T.D. (Thomas D), Flaxman, A.D. (Abraham D), Phillips, B.K. (Bryan K), Johnson, E.M. (Elizabeth), Coggeshall, M.S. (Megan S), Abd-Allah, F. (Foad), Abera, S.F. (Semaw Ferede), Abraham, J.P. (Jerry), Abubakar, I. (Ibrahim), Abu-Raddad, L.J. (Laith J), Abu-Rmeileh, N.M. (Niveen Me), Achoki, T. (Tom), Adeyemo, A. (Adebowale), Adou, A.K. (Arsène Kouablan), Adsuar, J.C. (José C), Agardh, E.E. (Emilie Elisabet), Akena, D. (Dickens), Al Kahbouri, M.J. (Mazin J), Alasfoor, D. (Deena), Albittar, M.I. (Mohammed I), Alcalá-Cerra, G. (Gabriel), Alegretti, M.A. (Miguel Angel), Alemu, G. (Getnet), Alfonso-Cristancho, R. (Rafael), Alhabib, S. (Samia), Ali, R. (Raghib), Alla, F. (Francois), Allen, P.J. (Peter), Alsharif, U. (Ubai), Alvarez, E. (Elena), Alvis-Guzman, N. (Nelson), Amankwaa, A.A. (Adansi A), Amare, A.T. (Azmeraw T), Amini, H. (Hassan), Ammar, K.A., Anderson, B.O. (Benjamin), Antonio, C.A.T. (Carl Abelardo T), Anwari, P. (Palwasha), Ärnlöv, J. (Johan), Arsenijevic, V.S.A. (Valentina S Arsic), Artaman, A. (Ali), Asghar, R.J. (Rana J), Assadi, R. (Reza), Atkins, L.S. (Lydia S), Badawi, A.F. (Alaa), Banerjee, A. (Amitava), Basu, S. (Saonli), Beardsley, J. (Justin), Bekele, T. (Tolesa), Bell, M.L. (Michelle Lee), Bernabe, E. (Eduardo), Beyene, T.J. (Tariku Jibat), Bhala, N. (Neeraj), Bhalla, P.L. (Pankaj), Bhutta, Z.A. (Zulfiqar A), Abdulhak, A.B. (Aref Bin), Binagwaho, A. (Agnes), Blore, J.D. (Jed D), Bose, D. (Dipan), Brainin, M. (Michael), Breitborde, N. (Nicholas), Castañeda-Orjuela, C.A. (Carlos A), Catalá-López, F. (Ferrán), Chadha, D., Chang, J.-C. (Jung-Chen), Chiang, Y.T., Chuang, T.-W. (Ting-Wu), Colomar, M. (Mercedes), Cooper Jr., L.T. (Leslie Trumbull), Cooper, C. (Charles), Courville, K.J. (Karen J), Cowie, M.R. (Martin R.), Criqui, M. (Michael), Dandona, R. (Rakhi), Dayama, A. (Anand), Leo, D. (Diego) de, Degenhardt, F., Del Pozo-Cruz, B. (Borja), Deribe, K. (Kebede), Des Jarlais, D.C. (Don C), Dessalegn, M. (Muluken), Dharmaratne, S.D. (Samath D), Dilmen, U. (Uǧur), Ding, E.L. (Eric), Driscoll, J.M., Durrani, Z., Ellenbogen, R.G. (Richard G), Ermakov, S. (Sergey), Esteghamati, A. (Alireza), Faraon, E.J.A. (Emerito Jose A), Farzadfar, F. (Farshad), Fereshtehnejad, S.-M. (Seyed-Mohammad), Fijabi, D.O. (Daniel Obadare), Forouzanfar, M.H. (Mohammad H), Fra.Paleo, U. (Urbano), Gaffikin, L. (Lynne), Gamkrelidze, A. (Amiran), Gankpé, F.G. (Fortuné Gbètoho), Geleijnse, J.M. (Marianne), Gessner, B.D. (Bradford D), Gibney, K.B. (Katherine B), Ginawi, I.A.M. (Ibrahim Abdelmageem Mohamed), Glaser, E.L. (Elizabeth L), Gona, P. (Philimon), Goto, A. (Akimoto), Gouda, H.N. (Hebe N), Gugnani, H.C. (Harish Chander), Gupta, R. (Rajeev), Hafezi-Nejad, N. (Nima), Hamadeh, R.R. (Randah Ribhi), Hammami, M. (Mouhanad), Hankey, G.J. (Graeme), Harb, H.L. (Hilda L), Haro, J.M. (Josep Maria), Havmoeller, R. (Rasmus), Hay, S.I. (Simon I), Hedayati, M.T. (Mohammad T), Pi, I.B.H. (Ileana B Heredia), Hoek, H.W. (Hans), Hornberger, J.C. (John C), Hosgood, H.D. (H Dean), Hotez, P.J. (Peter), Hoy, D.G. (Damian G), Huang, J. (Jian), Iburg, K.M. (Kim M), Idrisov, B.T. (Bulat T), Innos, K. (Kaire), Jacobsen, K.H. (Kathryn H), Jeemon, P. (Panniyammakal), Jensen, P.N. (Paul N), Jha, V. (Vivekanand), Jiang, G. (Guohong), Jonas, J.B., Juel, K. (Knud), Kan, H. (Haidong), Kankindi, I. (Ida), Karam, V. (Vincent), Karch, F. (Francois), Karema, C.K. (Corine Kakizi), Kaul, A. (Anil), Kawakami, N. (Norito), Kazi, D.S. (Dhruv S), Kemp, A.H. (Andrew H), Kengne, A.P. (Andre Pascal), Keren, A. (Andre), Kereselidze, M. (Maia), Khader, Y.S. (Yousef Saleh), Khalifa, S.E.A.H. (Shams Eldin Ali Hassan), Khan, E.A. (Ejaz Ahmed), Khang, Y.-H. (Young-Ho), Khonelidze, I. (Irma), Kinfu, Y. (Yohannes), Kinge, J.M. (Jonas M), Knibbs, L. (Luke), Kokubo, Y. (Yoshihiro), Kosen, S. (Soewarta), Defo, B.K. (Barthelemy Kuate), Kulkarni, V.S. (Veena S), Kulkarni, C. (Chanda), Kumar, K. (Kuldeep), Kumar, R.B. (Ravi B), Kumar, G.A. (G Anil), Kwan, G.F. (Gene F), Lai, T. (Taavi), Balaji, A.L. (Arjun Lakshmana), Lam, H. (Hilton), Lan, Q. (Qing), Lansingh, V.C. (Van C), Larson, H.J. (Heidi J), Larsson, A. (Anders), Lee, J.-T. (Jong-Tae), Leigh, P.N. (Nigel), Leinsalu, M. (Mall), Leung, R. (Ricky), Li, Y. (Yichong), Li, Y. (Yongmei), Lima, G.M.F. (Graça Maria Ferreira) de, Lin, H.-H. (Hsien-Ho), Lipshultz, S.E. (Steven), Liu, S. (Simin), Liu, Y. (Yang), Lloyd, B.K. (Belinda K), Lotufo, P.A. (Paulo A), Machado, V.M.P. (Vasco Manuel Pedro), Maclachlan, J.H. (Jennifer H), Magis-Rodriguez, C. (Carlos), Majdan, M. (Marek), Mapoma, C.C. (Christopher Chabila), Marcenes, W. (Wagner), Marzan, M.B. (Melvin Barrientos), Masci, J.R. (Joseph R), Mashal, R., Mason-Jones, A.J. (Amanda J), Mayosi, B.M. (Bongani), Mazorodze, T.T. (Tasara T), Mckay, M.J. (Michael), Meaney, M.J., Mehndiratta, M.M. (Man Mohan), Mejia-Rodriguez, F. (Fabiola), Melaku, Y.A. (Yohannes Adama), Memish, Z.A. (Ziad), Mendoza, W. (Walter), Miller, T.R. (Ted R), Mills, E.J. (Edward J), Mohammad, K.A. (Karzan Abdulmuhsin), Mokdad, A.H. (Ali H), Mola, G.L. (Glen Liddell), Monasta, L. (Lorenzo), Montico, M. (Marcella), Moore, A.R. (Ami R), Mori, R. (Riccardo), Moturi, W.N. (Wilkister Nyaora), Mukaigawara, M. (Mitsuru), Murthy, A.C. (Adeline C.), Naheed, A. (Aliya), Naidoo, K.S. (Kovin S), Naldi, L. (Lucia), Nangia, M. (Monika), Narayan, K.M.V. (Venkat), Nash, J.H.E. (John), Nejjari, C. (Chakib), Nelson, R.D. (Robert), Neupane, S.P. (Sudan Prasad), Newton, C. (Cameron), Ng, M. (Marie), Nisar, M.I. (Muhammad Imran), Nolte, S. (Sandra), Norheim, O.F. (Ole F), Nowaseb, V. (Vincent), Nyakarahuka, L. (Luke), Oh, I.-H. (In-Hwan), Ohkubo, T. (Takayoshi), Olusanya, B.O. (Bolajoko O), Omer, S.B. (Saad B), Opio, J.N. (John Nelson), Orisakwe, O.E. (Orish Ebere), Pandian, N.G. (Natesa), Papachristou, C., Caicedo, M.S. (Marco), Patten, J., Paul, V.K. (Vinod K), Pavlin, B.I. (Boris Igor), Pearce, N. (Neil), Pereira, D.M. (David M), Pervaiz, Z. (Zahid), Pesudovs, K. (Konrad), Petzold, M. (Max), Pourmalek, F. (Farshad), Qato, D. (Dima), Quezada, A.D. (Amado D), Quistberg, D.A. (D Alex), Rafay, A. (Anwar), Rahimi, K. (Kazem), Rahimi-Movaghar, V. (Vafa), Rahman, S.U. (Sajjad Ur), Raju, M. (Murugesan), Rana, S.M. (Saleem M), Razavi, H. (Homie), Reilly, R.Q. (Robert Quentin), Remuzzi, G. (Giuseppe), Richardus, J.H. (Jan Hendrik), Ronfani, L. (Luca), Roy, N. (Nadine) van, Sabin, M.L. (Miriam Lewis), Saeedi, M.Y. (Mohammad Yahya), Sahraian, M.A. (Mohammad Ali), Samonte, G.M.J. (Genesis May J), Sawhney, M.S. (Monika), Schneider, I.J.C. (Ione J C), Schwebel, D.C. (David C), Seedat, S. (Soraya), Sepanlou, S.G. (Sadaf G), Servan-Mori, E.E. (Edson E), Sheikhbahaei, S. (Sara), Shibuya, K. (Kenji), Shin, H.H. (Hwashin Hyun), Shiue, I. (Ivy), Shivakoti, R. (Rupak), Sigfusdottir, I.D. (Inga Dora), Silberberg, D.H. (Donald H), Silva, A.P. (Andrea P), Simard, J. (Jacques), Singh, J.A. (Jasvinder), Skirbekk, V. (Vegard), Sliwa, K. (Karen), Soneji, S. (Samir), Soshnikov, S.S. (Sergey S), Sreeramareddy, C.T. (Chandrashekhar T), Stathopoulou, V.K. (Vasiliki Kalliopi), Stroumpoulis, K. (Konstantinos), Swaminathan, S., Sykes, B.C. (Bryan), Tabb, K.M. (Karen M), Talongwa, R.T. (Roberto Tchio), Tenkorang, E.Y. (Eric Yeboah), Terkawi, A.S. (Abdullah Sulieman), Thomson, A.J. (Alan J), Thorne-Lyman, A.L. (Andrew L), Towbin, J.A. (Jeffrey A), Traebert, J. (Jefferson), Tran, B.X. (Bach X), Dimbuene, Z.T. (Zacharie Tsala), Tsilimbaris, M. (Miltiadis), Uchendu, U.S. (Uche S), Ukwaja, K.N. (Kingsley N), Vallely, S.R. (Stephen), Vasankari, T.J. (Tommi J), Venketasubramanian, N. (Narayanaswamy), Violante, F.S. (Francesco S), Vlassov, V.V. (Vasiliy Victorovich), Waller, P. (Patrick), Wallin, M.T. (Mitchell T), Wang, L. (Linhong), Wang, S.X., Wang, Y. (Yanping), Weichenthal, S. (Scott), Weiderpass, E. (Elisabete), Weintraub, R.G. (Robert G), Westerman, R. (Ronny), White, R.G. (Richard), Wilkinson, J.D. (James D), Williams, T.N. (Thomas Neil), Woldeyohannes, S.M. (Solomon Meseret), Wong, J.B. (John), Xu, G. (Gelin), Yang, Y.C. (Yang C), Yano, K.-I., Yip, P. (Paul), Yonemoto, N. (Naohiro), Yoon, S.-J. (Seok-Jun), Younis, M. (Mustafa), Yu, C. (Chuanhua), Jin, K.Y. (Kim Yun), El Sayed Zaki, M. (Maysaa), Zhao, Y. (Yong), Zheng, Y. (Yuhui), Balakrishnan, K. (Kalpana), Zhou, M. (Ming), Zhu, J. (Jun), Zou, X.N. (Xiao Nong), Lopez, A.D. (Alan D), and Vos, T. (Theo)
Abstract: __Abstract__ Background: The Millennium Declaration in 2000 brought special global attention to HIV, tuberculosis, and malaria through the formulation of Millennium Development Goal (MDG) 6. The Global Burden of Disease 2013 study provides a consistent and comprehensive approach to disease estimation for between 1990 and 2013, and an opportunity to assess whether accelerated progress has occured since the Millennium Declaration. Methods: To estimate incidence and mortality for HIV, we used the UNAIDS Spectrum model appropriately modified based on a systematic review of available studies of mortality with and without antiretroviral therapy (ART). For concentrated epidemics, we calibrated Spectrum models to fit vital registration data corrected for misclassification of HIV deaths. In generalised epidemics, we minimised a loss function to select epidemic curves most consistent with prevalence data and demographic data for all-cause mortality. We analysed counterfactual scenarios for HIV to assess years of life saved through prevention of mother-to-child transmission (PMTCT) and ART. For tuberculosis, we analysed vital registration and verbal autopsy data to estimate mortality using cause of death ensemble modelling. We analysed data for corrected case-notifications, expert opinions on the case-detection rate, prevalence surveys, and estimated cause-specific mortality using Bayesian meta-regression to generate consistent trends in all parameters. We analysed malaria mortality and incidence using an updated cause of death database, a systematic analysis of verbal autopsy validation studies for malaria, and recent studies (2010-13) of incidence, drug resistance, and coverage of insecticide-treated bednets. Findings: Globally in 2013, there were 1·8 million new HIV infections (95% uncertainty interval 1·7 million to 2·1 million), 29·2 million prevalent HIV cases (28·1 to 31·7), and 1·3 million HIV deaths (1·3 to 1·5). At the peak of the epidemic in 2005, HIV caused 1·7 mil
Published: 2014
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17. A genome-wide copy number association study of osteoporotic fractures points to the 6p25.1 locus

Author: Oei, L. (Ling), Hsu, Y.-H. (Yi-Hsiang), Styrkarsdottir, U. (Unnur), Eussen, H.J.F.M.M. (Bert), Klein, J.E.M.M. (Annelies) de, Peters, M.J. (Marjolein), Halldorsson, B.V. (Bjarni), Liu, C.-T. (Ching-Ti), Alonso, N. (Nerea), Kaptoge, S. (Stephen), Thorleifsson, G. (Gudmar), Hallmans, G. (Göran), Hocking, L.J. (Lynne), Husted, L.B. (Lise Bjerre), Jameson, K. (Karen), Kingdom, M.K. (Marcin KrUnited), Lewis, J.R. (Joshua), Patel, M.S. (Millan), Scollen, S. (Serena), Svensson, O. (Olle), Trompet, S. (Stella), Schoor, N.M. (Natasja) van, Zhu, K. (Kun), Buckley, B.M. (Brendan M.), Cooper, C. (Charles), Ford, I. (Ian), Goltzman, D. (David), González-Macías, J. (Jesús), Langdahl, B.L. (Bente), Leslie, W.D. (William), Lips, P. (Paul), Lorenc, R. (Roman), Olmos, D. (David), Pettersson-Kymmer, U. (Ulrika), Reid, D.M. (David), Riancho, J.A. (José), Slagboom, P.E. (Eline), Garcia-Ibarbia, C. (Carmen), Ingvarsson, T. (Torvaldur), Johannsdottir, H. (Hrefna), Luben, R.N. (Robert), Medina-Gomez, M.C. (Carolina), Arp, P.P. (Pascal), Nandakumar, K. (Kannabiran), Palsson, S.T. (Stefan Th), Sigurdsson, G. (Gunnar), Meurs, J.B.J. (Joyce) van, Zhou, Y. (Yanhua), Hofman, A. (Albert), Jukeme, J.W. (J. Wouter), Pols, H.A.P. (Huib), Prince, R.L. (Richard), Cupples, L.A. (Adrienne), Marshall, C.R. (Christian), Pinto, D. (Duane), Sato, D.K. (DaisUnited Kingdome), Scherer, S.W. (Stephen), Reeve, J. (Jonathan), Thorsteinsdottir, U. (Unnur), Karasik, D. (David), Richards, J.B. (Brent), Zwart, J-A. (John-Anker), Uitterlinden, A.G. (André), Ralston, S.H. (Stuart), Ioannidis, J.P.A. (John), Kiel, D.P. (Douglas), Rivadeneira Ramirez, F. (Fernando), Estrada Gil, K. (Karol), Oei, L. (Ling), Hsu, Y.-H. (Yi-Hsiang), Styrkarsdottir, U. (Unnur), Eussen, H.J.F.M.M. (Bert), Klein, J.E.M.M. (Annelies) de, Peters, M.J. (Marjolein), Halldorsson, B.V. (Bjarni), Liu, C.-T. (Ching-Ti), Alonso, N. (Nerea), Kaptoge, S. (Stephen), Thorleifsson, G. (Gudmar), Hallmans, G. (Göran), Hocking, L.J. (Lynne), Husted, L.B. (Lise Bjerre), Jameson, K. (Karen), Kingdom, M.K. (Marcin KrUnited), Lewis, J.R. (Joshua), Patel, M.S. (Millan), Scollen, S. (Serena), Svensson, O. (Olle), Trompet, S. (Stella), Schoor, N.M. (Natasja) van, Zhu, K. (Kun), Buckley, B.M. (Brendan M.), Cooper, C. (Charles), Ford, I. (Ian), Goltzman, D. (David), González-Macías, J. (Jesús), Langdahl, B.L. (Bente), Leslie, W.D. (William), Lips, P. (Paul), Lorenc, R. (Roman), Olmos, D. (David), Pettersson-Kymmer, U. (Ulrika), Reid, D.M. (David), Riancho, J.A. (José), Slagboom, P.E. (Eline), Garcia-Ibarbia, C. (Carmen), Ingvarsson, T. (Torvaldur), Johannsdottir, H. (Hrefna), Luben, R.N. (Robert), Medina-Gomez, M.C. (Carolina), Arp, P.P. (Pascal), Nandakumar, K. (Kannabiran), Palsson, S.T. (Stefan Th), Sigurdsson, G. (Gunnar), Meurs, J.B.J. (Joyce) van, Zhou, Y. (Yanhua), Hofman, A. (Albert), Jukeme, J.W. (J. Wouter), Pols, H.A.P. (Huib), Prince, R.L. (Richard), Cupples, L.A. (Adrienne), Marshall, C.R. (Christian), Pinto, D. (Duane), Sato, D.K. (DaisUnited Kingdome), Scherer, S.W. (Stephen), Reeve, J. (Jonathan), Thorsteinsdottir, U. (Unnur), Karasik, D. (David), Richards, J.B. (Brent), Zwart, J-A. (John-Anker), Uitterlinden, A.G. (André), Ralston, S.H. (Stuart), Ioannidis, J.P.A. (John), Kiel, D.P. (Douglas), Rivadeneira Ramirez, F. (Fernando), and Estrada Gil, K. (Karol)
Abstract: Background Osteoporosis is a systemic skeletal disease characterised by reduced bone mineral density and increased susceptibility to fracture; these traits are highly heritable. Both common and rare copy number variants (CNVs) potentially affect the function of genes and may influence disease risk. Aim To identify CNVs associated with osteoporotic bone fracture risk. Method We performed a genome-wide CNV association study in 5178 individuals from a prospective cohort in the Netherlands, including 809 osteoporotic fracture cases, and performed in silico lookups and de novo genotyping to replicate in several independent studies. Results A rare (population prevalence 0.14%, 95% CI 0.03% to 0.24%) 210 kb deletion located on chromosome 6p25.1 was associated with the risk of fracture (OR 32.58, 95% CI 3.95 to 1488.89; p=8.69×10−5). We performed an in silico meta-analysis in four studies with CNV microarray data and the association with fracture risk was replicated (OR 3.11, 95% CI 1.01 to 8.22; p=0.02). The prevalence of this deletion showed geographic diversity, being absent in additional samples from Australia, Canada, Poland, Iceland, Denmark, and Sweden, but present in the Netherlands (0.34%), Spain (0.33%), USA (0.23%), England (0.15%), Scotland (0.10%), and Ireland (0.06%), with insufficient evidence for association with fracture risk. Conclusions These results suggest that deletions in the 6p25.1 locus may predispose to higher risk of fracture in a subset of populations of European origin; larger and geographically restricted studies will be needed to confirm this regional association. This is a first step towards the evaluation of the role of rare CNVs in osteoporosis.
Published: 2014
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18. A reference case for economic evaluations in osteoarthritis: An expert consensus article from the European Society for Clinical and Economic Aspects of Osteoporosis and Osteoarthritis (ESCEO)

Author: Hiligsmann, M. (Mickael), Cooper, C. (Charles), Guillemin, F. (F.), Hochberg, M.C. (Marc), Tugwell, P. (Peter), Arden, N.K. (Nigel), Berenbaum, F. (Francis), Boers, M. (Maarten), Boonen, A. (Annelies), Branco, M.R. (Miguel), Maria-Luisa, B. (Brandi), Bruyère, F. (Françoise), Gasparik, A. (Andrea), Kanis, J.A. (John), Kvien, T.K. (Tore), Martel-Pelletier, J. (Johanne), Pelletier, J.-P. (Jean-Pierre), Pinedo-Villanueva, R. (Rafael), Pinto, D. (Daniel), Reiter-Niesert, S. (Susanne), Rizzoli, R., Rovati, L.C. (Lucio), Severens, J.L. (Hans), Silverman, S. (Stuart), Reginster, J-Y. (Jean-Yves), Hiligsmann, M. (Mickael), Cooper, C. (Charles), Guillemin, F. (F.), Hochberg, M.C. (Marc), Tugwell, P. (Peter), Arden, N.K. (Nigel), Berenbaum, F. (Francis), Boers, M. (Maarten), Boonen, A. (Annelies), Branco, M.R. (Miguel), Maria-Luisa, B. (Brandi), Bruyère, F. (Françoise), Gasparik, A. (Andrea), Kanis, J.A. (John), Kvien, T.K. (Tore), Martel-Pelletier, J. (Johanne), Pelletier, J.-P. (Jean-Pierre), Pinedo-Villanueva, R. (Rafael), Pinto, D. (Daniel), Reiter-Niesert, S. (Susanne), Rizzoli, R., Rovati, L.C. (Lucio), Severens, J.L. (Hans), Silverman, S. (Stuart), and Reginster, J-Y. (Jean-Yves)
Abstract: Background: General recommendations for a reference case for economic studies in rheumatic diseases were published in 2002 in an initiative to improve the comparability of cost-effectiveness studies in the field. Since then, economic evaluations in osteoarthritis (OA) continue to show considerable heterogeneity in methodological approach. Objectives: To develop a reference case specific for economic studies in OA, including the standard optimal care, with which to judge new pharmacologic and non-pharmacologic interventions. Methods: Four subgroups of an ESCEO expert working group on economic assessments (13 experts representing diverse aspects of clinical research and/or economic evaluations) were charged with producing lists of recommendations that would potentially improve the comparability of economic analyses in OA: outcome measures, comparators, costs and methodology. These proposals were discussed and refined during a face-to-face meeting in 2013. They are presented here in the format of the recommendations of the recently published Consolidated Health Economic Evaluation Reporting Standards (CHEERS) statement, so that an initiative on economic analysis methodology might be consolidated with an initiative on reporting standards. Results: Overall, three distinct reference cases are proposed, one for each hand, knee and hip OA; with diagnostic variations in the first two, giving rise to different treatment options: interphalangeal or thumb-based disease for hand OA and the presence or absence of joint malalignment for knee OA. A set of management strategies is proposed, which should be further evaluated to help establish a consensus on the "standard optimal care" in each proposed reference case. The recommendations on outcome measures, cost itemisation and methodological approaches are also provided. Conclusions: The ESCEO group proposes a set of disease-specific recommendations on the conduct and reporting of economic evaluations in OA that could help the stand
Published: 2014
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19. Health economics in the field of osteoarthritis: An Expert's consensus paper from the European Society for Clinical and Economic Aspects of Osteoporosis and Osteoarthritis (ESCEO)

Author: Hiligsmann, M. (Mickael), Cooper, C. (Charles), Arden, N.K. (Nigel), Boers, M. (Maarten), Branco, M.R. (Miguel), Luisa Brandi, M. (Maria), Bruyère, F. (Françoise), Guillemin, F. (Francis), Hochberg, M.C. (Marc), Hunter, D.J. (David), Kanis, J.A. (John), Kvien, T.K. (Tore), Laslop, A. (Andrea), Pelletier, C. (Cory), Pinto, D. (Duane), Reiter-Niesert, S. (Susanne), Rizzoli, R., Rovati, L.C. (Lucio), Severens, J.L. (Hans), Silverman, S. (Stuart), Tsouderos, Y. (Yannis), Tugwell, P. (Peter), Reginster, J-Y. (Jean-Yves), Hiligsmann, M. (Mickael), Cooper, C. (Charles), Arden, N.K. (Nigel), Boers, M. (Maarten), Branco, M.R. (Miguel), Luisa Brandi, M. (Maria), Bruyère, F. (Françoise), Guillemin, F. (Francis), Hochberg, M.C. (Marc), Hunter, D.J. (David), Kanis, J.A. (John), Kvien, T.K. (Tore), Laslop, A. (Andrea), Pelletier, C. (Cory), Pinto, D. (Duane), Reiter-Niesert, S. (Susanne), Rizzoli, R., Rovati, L.C. (Lucio), Severens, J.L. (Hans), Silverman, S. (Stuart), Tsouderos, Y. (Yannis), Tugwell, P. (Peter), and Reginster, J-Y. (Jean-Yves)
Abstract: Objectives: There is an important need to evaluate therapeutic approaches for osteoarthritis (OA) in terms of cost-effectiveness as well as
Published: 2013
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20. Genome-wide association study meta-analysis of chronic widespread pain: Evidence for involvement of the 5p15.2 region

Author: Peters, M.J. (Marjolein), Broer, L. (Linda), Willemen, H.L.D.M. (Hanneke), Eiriksdottir, G. (Gudny), Hocking, L.J. (Lynne), Holliday, K.L. (Kate), Horan, M. (Mike), Meulenbelt, I. (Ingrid), Neogi, T. (Tuhina), Popham, M. (Maria), Schmidt, C.O. (Carsten Oliver), Soni, B., Valdes, A.M. (Ana Maria), Amin, N. (Najaf), Dennison, E.M. (Elaine), Eijkelkamp, B. (Bart), Harris, T.B. (Tamara), Hart, D.J. (Deborah), Hofman, A. (Albert), Huygen, F.J.P.M. (Frank), Jameson, K. (Karen), Jones, G.T. (Gregory), Launer, L.J. (Lenore), Kerkhof, J.M. (Hanneke), Kruijf, M. (Marjolein) de, McBeth, J. (John), Kloppenburg, M. (Margreet), Ollier, W.E.R. (William), Oostra, B.A. (Ben), Payton, A. (Antony), Rivadeneira Ramirez, F. (Fernando), Smith, B.H. (Blair), Smith, A.V. (Davey), Stolk, L. (Lisette), Teumer, A. (Alexander), Thomson, W. (Wendy), Uitterlinden, A.G. (André), Wang, K. (Ke), Wingerden, S. (Sophie) van, Arden, N.K. (Nigel), Cooper, C. (Charles), Felson, D., Gudnason, V. (Vilmundur), Macfarlane, G.J. (Gary), Pendleton, N. (Neil), Slagboom, P.E. (Eline), Spector, T.D. (Timothy), Volzke, H. (Henry), Kavelaars, A. (Annemieke), Duijn, C.M. (Cornelia) van, Williams, F.M. (Frances), Meurs, J.B.J. (Joyce) van, Peters, M.J. (Marjolein), Broer, L. (Linda), Willemen, H.L.D.M. (Hanneke), Eiriksdottir, G. (Gudny), Hocking, L.J. (Lynne), Holliday, K.L. (Kate), Horan, M. (Mike), Meulenbelt, I. (Ingrid), Neogi, T. (Tuhina), Popham, M. (Maria), Schmidt, C.O. (Carsten Oliver), Soni, B., Valdes, A.M. (Ana Maria), Amin, N. (Najaf), Dennison, E.M. (Elaine), Eijkelkamp, B. (Bart), Harris, T.B. (Tamara), Hart, D.J. (Deborah), Hofman, A. (Albert), Huygen, F.J.P.M. (Frank), Jameson, K. (Karen), Jones, G.T. (Gregory), Launer, L.J. (Lenore), Kerkhof, J.M. (Hanneke), Kruijf, M. (Marjolein) de, McBeth, J. (John), Kloppenburg, M. (Margreet), Ollier, W.E.R. (William), Oostra, B.A. (Ben), Payton, A. (Antony), Rivadeneira Ramirez, F. (Fernando), Smith, B.H. (Blair), Smith, A.V. (Davey), Stolk, L. (Lisette), Teumer, A. (Alexander), Thomson, W. (Wendy), Uitterlinden, A.G. (André), Wang, K. (Ke), Wingerden, S. (Sophie) van, Arden, N.K. (Nigel), Cooper, C. (Charles), Felson, D., Gudnason, V. (Vilmundur), Macfarlane, G.J. (Gary), Pendleton, N. (Neil), Slagboom, P.E. (Eline), Spector, T.D. (Timothy), Volzke, H. (Henry), Kavelaars, A. (Annemieke), Duijn, C.M. (Cornelia) van, Williams, F.M. (Frances), and Meurs, J.B.J. (Joyce) van
Published: 2013
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21. Genome-wide meta-analysis identifies 56 bone mineral density loci and reveals 14 loci associated with risk of fracture

Author: Estrada Gil, K. (Karol), Styrkarsdottir, U. (Unnur), Evangelou, E. (Evangelos), Hsu, Y.-H. (Yi-Hsiang), Duncan, E.L. (Emma), Ntzani, E.E. (Evangelia), Oei, L. (Ling), Albagha, O.M.E. (Omar M.), Amin, N. (Najaf), Kemp, J.P. (John), Koller, D.L. (Daniel), Li, G. (Guo), Liu, C.-T. (Ching-Ti), Minster, R.L. (Ryan), Moayyeri, A. (Alireza), Vandenput, L. (Liesbeth), Willner, D. (Dana), Xiao, S.-M. (Su-Mei), Yerges-Armstrong, L.M. (Laura), Zheng, H.-F. (Hou-Feng), Alonso, N. (Nerea), Eriksson, J. (Joel), Kammerer, C.M. (Candace), Kaptoge, S. (Stephen), Leo, P.J. (Paul), Thorleifsson, G. (Gudmar), Wilson, S.G. (Scott), Wilson, J.F. (James), Aalto, V. (Ville), Alen, T.A. (Theo) van, Aragaki, A.K. (Aaron), Aspelund, T. (Thor), Center, J.R. (Jacqueline), Dailiana, Z. (Zoe), Duggan, C., Garcia, M. (Melissa), Garcia-Giralt, N. (Natàlia), Giroux, S. (Sylvie), Hallmans, G. (Göran), Hocking, L.J. (Lynne), Husted, L.B. (Lise Bjerre), Jameson, K. (Karen), Khusainova, R. (Rita), Kim, G.S. (Ghi Su), Kooperberg, C. (Charles), Koromila, T. (Theodora), Kruk, M. (Marcin), Laaksonen, M. (Marika), LaCroix, A.Z. (Andrea), Lee, S.U. (Seung), Leung, P.C. (Ping), Lewis, J.R. (Joshua), Masi, L. (Laura), Mencej-Bedrac, S. (Simona), Nguyen, T.V. (Tuan), Nogues, X. (Xavier), Patel, M.S. (Millan), Prezelj, J. (Janez), Rose, L.M. (Lynda), Scollen, S. (Serena), Siggeirsdottir, K. (Kristin), Smith, A.V. (Davey), Svensson, O. (Olle), Trompet, S. (Stella), Trummer, O. (Olivia), Schoor, N.M. (Natasja) van, Woo, M.M. (Margaret M.), Zhu, K. (Kun), Balcells, S. (Susana), Brandi, M.L., Buckley, B.M. (Brendan M.), Cheng, S. (Sulin), Christiansen, C., Cooper, C. (Charles), Dedoussis, G.V. (George), Ford, I. (Ian), Frost, M. (Morten), Goltzman, D. (David), González-Macías, J. (Jesús), Kähönen, M. (Mika), Karlsson, M. (Magnus), Khusnutdinova, E.K. (Elza), Koh, J.-M. (Jung-Min), Kollia, P. (Panagoula), Langdahl, B.L. (Bente), Leslie, W.D. (William), Lips, P. (Paul), Ljunggren, O. (Östen), Lorenc, R. (Roman), Marc, J. (Janja), Mellström, D. (Dan), Obermayer-Pietsch, B. (Barbara), Olmos, D. (David), Pettersson-Kymmer, U. (Ulrika), Reid, D.M. (David), Riancho, J.A. (José), Ridker, P.M. (Paul), Rousseau, M.F. (Francois), Slagboom, P.E. (Eline), Tang, N.L.S. (Nelson L.), Urreizti, R. (Roser), Van Hul, W. (Wim), Viikari, J. (Jorma), Zarrabeitia, M.T. (María), Aulchenko, Y.S. (Yurii), Castaño Betancourt, M.C. (Martha), Grundberg, E. (Elin), Herrera, L. (Lizbeth), Ingvarsson, T. (Torvaldur), Johannsdottir, H. (Hrefna), Kwan, T. (Tony), Li, R. (Rui), Luben, R.N. (Robert), Medina-Gomez, M.C. (Carolina), Palsson, S.T. (Stefan), Reppe, S. (Sjur), Rotter, J.I. (Jerome), Sigurdsson, G. (Gunnar), Meurs, J.B.J. (Joyce) van, Verlaan, D.J. (Dominique), Williams, F.M. (Frances), Wood, A.R. (Andrew), Zhou, Y. (Yanhua), Gautvik, K.M. (Kaare), Pastinen, T. (Tomi), Raychaudhuri, S. (Soumya), Cauley, J.A. (Jane), Chasman, D.I. (Daniel), Clark, G.R. (Graeme), Cummings, S., Danoy, P. (Patrick), Dennison, E.M. (Elaine), Eastell, R. (Richard), Eisman, J.A. (John), Gudnason, V. (Vilmundur), Hofman, A. (Albert), Jackson, R.D. (Rebecca), Jones, G. (Graeme), Jukema, J.W. (Jan Wouter), Khaw, K-T. (Kay-Tee), Lehtimäki, T. (Terho), Liu, Y. (YongMei), Lorentzon, M. (Mattias), McCloskey, E.V. (Eugene), Mitchell, B.D. (Braxton), Nandakumar, K. (Kannabiran), Nicholson, G.C. (Geoffrey), Oostra, B.A. (Ben), Peacock, M. (Munro), Pols, H.A.P. (Huib), Prince, R.L. (Richard), Raitakari, O. (Olli), Reid, I.R. (Ian), Robbins, J. (John), Sambrook, P.N. (Philip), Sham, P.C. (Pak), Shuldiner, A.R. (Alan), Tylavsky, F.A. (Frances), Duijn, C.M. (Cornelia) van, Wareham, N.J. (Nick), Cupples, L.A. (Adrienne), Econs, M.J. (Michael), Evans, D.M. (David), Harris, T.B. (Tamara), Kung, A.W.C. (Annie), Psaty, B.M. (Bruce), Reeve, J. (Jonathan), Spector, T.D. (Timothy), Streeten, E.A. (Elizabeth), Zillikens, M.C. (Carola), Thorsteinsdottir, U. (Unnur), Ohlsson, C. (Claes), Karasik, D. (David), Richards, J.B. (Brent), Brown, M.A. (Matthew), Zwart, J-A. (John-Anker), Uitterlinden, A.G. (André), Ralston, S.H. (Stuart), Ioannidis, J.P.A. (John), Kiel, D.P. (Douglas), Rivadeneira Ramirez, F. (Fernando), Estrada Gil, K. (Karol), Styrkarsdottir, U. (Unnur), Evangelou, E. (Evangelos), Hsu, Y.-H. (Yi-Hsiang), Duncan, E.L. (Emma), Ntzani, E.E. (Evangelia), Oei, L. (Ling), Albagha, O.M.E. (Omar M.), Amin, N. (Najaf), Kemp, J.P. (John), Koller, D.L. (Daniel), Li, G. (Guo), Liu, C.-T. (Ching-Ti), Minster, R.L. (Ryan), Moayyeri, A. (Alireza), Vandenput, L. (Liesbeth), Willner, D. (Dana), Xiao, S.-M. (Su-Mei), Yerges-Armstrong, L.M. (Laura), Zheng, H.-F. (Hou-Feng), Alonso, N. (Nerea), Eriksson, J. (Joel), Kammerer, C.M. (Candace), Kaptoge, S. (Stephen), Leo, P.J. (Paul), Thorleifsson, G. (Gudmar), Wilson, S.G. (Scott), Wilson, J.F. (James), Aalto, V. (Ville), Alen, T.A. (Theo) van, Aragaki, A.K. (Aaron), Aspelund, T. (Thor), Center, J.R. (Jacqueline), Dailiana, Z. (Zoe), Duggan, C., Garcia, M. (Melissa), Garcia-Giralt, N. (Natàlia), Giroux, S. (Sylvie), Hallmans, G. (Göran), Hocking, L.J. (Lynne), Husted, L.B. (Lise Bjerre), Jameson, K. (Karen), Khusainova, R. (Rita), Kim, G.S. (Ghi Su), Kooperberg, C. (Charles), Koromila, T. (Theodora), Kruk, M. (Marcin), Laaksonen, M. (Marika), LaCroix, A.Z. (Andrea), Lee, S.U. (Seung), Leung, P.C. (Ping), Lewis, J.R. (Joshua), Masi, L. (Laura), Mencej-Bedrac, S. (Simona), Nguyen, T.V. (Tuan), Nogues, X. (Xavier), Patel, M.S. (Millan), Prezelj, J. (Janez), Rose, L.M. (Lynda), Scollen, S. (Serena), Siggeirsdottir, K. (Kristin), Smith, A.V. (Davey), Svensson, O. (Olle), Trompet, S. (Stella), Trummer, O. (Olivia), Schoor, N.M. (Natasja) van, Woo, M.M. (Margaret M.), Zhu, K. (Kun), Balcells, S. (Susana), Brandi, M.L., Buckley, B.M. (Brendan M.), Cheng, S. (Sulin), Christiansen, C., Cooper, C. (Charles), Dedoussis, G.V. (George), Ford, I. (Ian), Frost, M. (Morten), Goltzman, D. (David), González-Macías, J. (Jesús), Kähönen, M. (Mika), Karlsson, M. (Magnus), Khusnutdinova, E.K. (Elza), Koh, J.-M. (Jung-Min), Kollia, P. (Panagoula), Langdahl, B.L. (Bente), Leslie, W.D. (William), Lips, P. (Paul), Ljunggren, O. (Östen), Lorenc, R. (Roman), Marc, J. (Janja), Mellström, D. (Dan), Obermayer-Pietsch, B. (Barbara), Olmos, D. (David), Pettersson-Kymmer, U. (Ulrika), Reid, D.M. (David), Riancho, J.A. (José), Ridker, P.M. (Paul), Rousseau, M.F. (Francois), Slagboom, P.E. (Eline), Tang, N.L.S. (Nelson L.), Urreizti, R. (Roser), Van Hul, W. (Wim), Viikari, J. (Jorma), Zarrabeitia, M.T. (María), Aulchenko, Y.S. (Yurii), Castaño Betancourt, M.C. (Martha), Grundberg, E. (Elin), Herrera, L. (Lizbeth), Ingvarsson, T. (Torvaldur), Johannsdottir, H. (Hrefna), Kwan, T. (Tony), Li, R. (Rui), Luben, R.N. (Robert), Medina-Gomez, M.C. (Carolina), Palsson, S.T. (Stefan), Reppe, S. (Sjur), Rotter, J.I. (Jerome), Sigurdsson, G. (Gunnar), Meurs, J.B.J. (Joyce) van, Verlaan, D.J. (Dominique), Williams, F.M. (Frances), Wood, A.R. (Andrew), Zhou, Y. (Yanhua), Gautvik, K.M. (Kaare), Pastinen, T. (Tomi), Raychaudhuri, S. (Soumya), Cauley, J.A. (Jane), Chasman, D.I. (Daniel), Clark, G.R. (Graeme), Cummings, S., Danoy, P. (Patrick), Dennison, E.M. (Elaine), Eastell, R. (Richard), Eisman, J.A. (John), Gudnason, V. (Vilmundur), Hofman, A. (Albert), Jackson, R.D. (Rebecca), Jones, G. (Graeme), Jukema, J.W. (Jan Wouter), Khaw, K-T. (Kay-Tee), Lehtimäki, T. (Terho), Liu, Y. (YongMei), Lorentzon, M. (Mattias), McCloskey, E.V. (Eugene), Mitchell, B.D. (Braxton), Nandakumar, K. (Kannabiran), Nicholson, G.C. (Geoffrey), Oostra, B.A. (Ben), Peacock, M. (Munro), Pols, H.A.P. (Huib), Prince, R.L. (Richard), Raitakari, O. (Olli), Reid, I.R. (Ian), Robbins, J. (John), Sambrook, P.N. (Philip), Sham, P.C. (Pak), Shuldiner, A.R. (Alan), Tylavsky, F.A. (Frances), Duijn, C.M. (Cornelia) van, Wareham, N.J. (Nick), Cupples, L.A. (Adrienne), Econs, M.J. (Michael), Evans, D.M. (David), Harris, T.B. (Tamara), Kung, A.W.C. (Annie), Psaty, B.M. (Bruce), Reeve, J. (Jonathan), Spector, T.D. (Timothy), Streeten, E.A. (Elizabeth), Zillikens, M.C. (Carola), Thorsteinsdottir, U. (Unnur), Ohlsson, C. (Claes), Karasik, D. (David), Richards, J.B. (Brent), Brown, M.A. (Matthew), Zwart, J-A. (John-Anker), Uitterlinden, A.G. (André), Ralston, S.H. (Stuart), Ioannidis, J.P.A. (John), Kiel, D.P. (Douglas), and Rivadeneira Ramirez, F. (Fernando)
Abstract: Bone mineral density (BMD) is the most widely used predictor of fracture risk. We performed the largest meta-analysis to date on lumbar spine and femoral neck BMD, including 17 genome-wide association studies and 32,961 individuals of European and east Asian ancestry. We tested the top BMD-associated markers for replication in 50,933 independent subjects and for association with risk of low-trauma fracture in 31,016 individuals with a history of fracture (cases) and 102,444 controls. We identified 56 loci (32 new) associated with BMD at genome-wide significance (P < 5 × 10 -8). Several of these factors cluster within the RANK-RANKL-OPG, mesenchymal stem cell differentiation, endochondral ossification and Wnt signaling pathways. However, we also discovered loci that were localized to genes not known to have a role in bone biology. Fourteen BMD-associated loci were also associated with fracture risk (P < 5 × 10 -4, Bonferroni corrected), of which six reached P < 5 × 10 -8, including at 18p11.21 (FAM210A), 7q21.3 (SLC25A13), 11q13.2 (LRP5), 4q22.1 (MEPE), 2p16.2 (SPTBN1) and 10q21.1 (DKK1). These findings shed light on the genetic architecture and pathophysiological mechanisms underlying BMD variation and fracture susceptibility.
Published: 2012
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22. Common variants at 6q22 and 17q21 are associated with intracranial volume

Author: Ikram, M.A. (Arfan), Fornage, M. (Myriam), Smith, A.V. (Davey), Seshadri, S. (Sudha), Schmidt, R. (Reinhold), Debette, S. (Stéphanie), Vrooman, H.A. (Henri), Sigurdsson, S. (Stefan), Ropele, S. (Stefan), Taal, H.R. (Rob), Mook-Kanamori, D.O. (Dennis), Coker, L.H. (Laura), Longstreth Jr, W.T., Niessen, W.J. (Wiro), DeStefano, A.L. (Anita), Beiser, A. (Alexa), Zijdenbos, A.P., Struchalin, M.V. (Maksim), Jack Jr., C.R. (Clifford), Rivadeneira Ramirez, F. (Fernando), Uitterlinden, A.G. (André), Knopman, D.S. (David), Hartikainen, A.L., Pennell, C.E. (Craig), Thiering, E. (Eelisabeth), Steegers, E.A.P. (Eric), Hakonarson, H. (Hakon), Heinrich, J. (Joachim), Palmer, C. (Cameron), Jarvelin, M.-R. (Marjo-Riitta), McCarthy, M.I. (Mark), Grant, S.F.A. (Struan), Pourcain, B.S. (Beate), Timpson, N.J. (Nicholas), Sovio, U. (Ulla), Nalls, M.A. (Michael), Au, R. (Rhoda), Hofman, A. (Albert), Gudnason, H. (Haukur), Lugt, A. (Aad) van der, Harris, T.B. (Tamara), Meeks, W.M. (William), Vernooij, M.W. (Meike), Buchem, M.A. (Mark) van, Catellier, D.J. (Diane), Jaddoe, V.W.V. (Vincent), Gudnason, V. (Vilmundur), Windham, B.G. (Gwen), Wolf, P.A. (Philip), Duijn, C.M. (Cornelia) van, Mosley, T.H. (Thomas), Launer, L.J. (Lenore), Breteler, M.M.B. (Monique), DeCarli, C. (Charles), Adair, L.S. (Linda), Ang, W.Q. (Wei), Atalay, M. (Mustafa), Beijsterveldt, C.E.M. (Toos) van, Bergen, N.E. (Nienke), Benke, P.J. (Paul), Berry, D. (Diane), Coin, L. (Lachlan), Davis, O.S.P. (Oliver S.), Elliott, P. (Paul), Flexeder, C. (Claudia), Frayling, T.M. (Timothy), Gaillard, R. (Romy), Groen-Blokhuis, M. (Maria), Goh, L.-K., Haworth, C.M.A. (Claire M.), Hadley, D. (David), Hedebrand, J. (Johannes), Hinney, A. (Anke), Hirschhorn, J.N. (Joel), Holloway, J.W. (John), Holst, J.J., Hottenga, J.J. (Jouke Jan), Horikoshi, M. (Momoko), Huikari, V. (Ville), Hypponen, E. (Elina), Kilpeläinen, T.O. (Tuomas), Kirin, M. (Mirna), Kowgier, M. (Matthew), Lakka, T.A. (Timo), Lange, L.A. (Leslie), Lawlor, D.A. (Debbie), Lehtimäki, T. (Terho), Lewin, A. (Alex), Lindgren, C.M. (Cecilia), Lindi, V. (Virpi), Maggi, R. (Reedik), Marsh, J.A. (Julie), Middeldorp, C.M. (Christel), Millwood, I.Y. (Iona), Murray, J.C. (Jeffrey), Nivard, M. (Michel), Nohr, C. (Christian), Ntalla, I. (Ioanna), Oken, E. (Emily), Panoutsopoulou, K. (Kalliope), Pararajasingham, J. (Jennifer), Rodriguez, A. (Alfredo Chapin), Salem, R.M. (Rany), Sebert, S. (Sylvain), Siitonen, N. (Niina), Strachan, D.P. (David), Teo, Y.Y. (Yik Ying), Valcárcel, B. (Beatriz), Willemsen, G.A.H.M. (Gonneke), Zeggini, E. (Eleftheria), Boomsma, D.I. (Dorret), Cooper, C. (Charles), Gillman, M.H. (Matthew), Hocher, B. (Berthold), Mohlke, K.L. (Karen), Dedoussis, G.V. (George), Ong, K.K. (Ken), Pearson, E. (Ewan), Price, T.S. (Thomas), Power, C. (Christopher), Raitakari, O. (Olli), Saw, S-M. (Seang-Mei), Scherag, A. (Andre), Simell, O. (Olli), Sørensen, T.I.A. (Thorkild), Wilson, J.F. (James), Ikram, M.A. (Arfan), Fornage, M. (Myriam), Smith, A.V. (Davey), Seshadri, S. (Sudha), Schmidt, R. (Reinhold), Debette, S. (Stéphanie), Vrooman, H.A. (Henri), Sigurdsson, S. (Stefan), Ropele, S. (Stefan), Taal, H.R. (Rob), Mook-Kanamori, D.O. (Dennis), Coker, L.H. (Laura), Longstreth Jr, W.T., Niessen, W.J. (Wiro), DeStefano, A.L. (Anita), Beiser, A. (Alexa), Zijdenbos, A.P., Struchalin, M.V. (Maksim), Jack Jr., C.R. (Clifford), Rivadeneira Ramirez, F. (Fernando), Uitterlinden, A.G. (André), Knopman, D.S. (David), Hartikainen, A.L., Pennell, C.E. (Craig), Thiering, E. (Eelisabeth), Steegers, E.A.P. (Eric), Hakonarson, H. (Hakon), Heinrich, J. (Joachim), Palmer, C. (Cameron), Jarvelin, M.-R. (Marjo-Riitta), McCarthy, M.I. (Mark), Grant, S.F.A. (Struan), Pourcain, B.S. (Beate), Timpson, N.J. (Nicholas), Sovio, U. (Ulla), Nalls, M.A. (Michael), Au, R. (Rhoda), Hofman, A. (Albert), Gudnason, H. (Haukur), Lugt, A. (Aad) van der, Harris, T.B. (Tamara), Meeks, W.M. (William), Vernooij, M.W. (Meike), Buchem, M.A. (Mark) van, Catellier, D.J. (Diane), Jaddoe, V.W.V. (Vincent), Gudnason, V. (Vilmundur), Windham, B.G. (Gwen), Wolf, P.A. (Philip), Duijn, C.M. (Cornelia) van, Mosley, T.H. (Thomas), Launer, L.J. (Lenore), Breteler, M.M.B. (Monique), DeCarli, C. (Charles), Adair, L.S. (Linda), Ang, W.Q. (Wei), Atalay, M. (Mustafa), Beijsterveldt, C.E.M. (Toos) van, Bergen, N.E. (Nienke), Benke, P.J. (Paul), Berry, D. (Diane), Coin, L. (Lachlan), Davis, O.S.P. (Oliver S.), Elliott, P. (Paul), Flexeder, C. (Claudia), Frayling, T.M. (Timothy), Gaillard, R. (Romy), Groen-Blokhuis, M. (Maria), Goh, L.-K., Haworth, C.M.A. (Claire M.), Hadley, D. (David), Hedebrand, J. (Johannes), Hinney, A. (Anke), Hirschhorn, J.N. (Joel), Holloway, J.W. (John), Holst, J.J., Hottenga, J.J. (Jouke Jan), Horikoshi, M. (Momoko), Huikari, V. (Ville), Hypponen, E. (Elina), Kilpeläinen, T.O. (Tuomas), Kirin, M. (Mirna), Kowgier, M. (Matthew), Lakka, T.A. (Timo), Lange, L.A. (Leslie), Lawlor, D.A. (Debbie), Lehtimäki, T. (Terho), Lewin, A. (Alex), Lindgren, C.M. (Cecilia), Lindi, V. (Virpi), Maggi, R. (Reedik), Marsh, J.A. (Julie), Middeldorp, C.M. (Christel), Millwood, I.Y. (Iona), Murray, J.C. (Jeffrey), Nivard, M. (Michel), Nohr, C. (Christian), Ntalla, I. (Ioanna), Oken, E. (Emily), Panoutsopoulou, K. (Kalliope), Pararajasingham, J. (Jennifer), Rodriguez, A. (Alfredo Chapin), Salem, R.M. (Rany), Sebert, S. (Sylvain), Siitonen, N. (Niina), Strachan, D.P. (David), Teo, Y.Y. (Yik Ying), Valcárcel, B. (Beatriz), Willemsen, G.A.H.M. (Gonneke), Zeggini, E. (Eleftheria), Boomsma, D.I. (Dorret), Cooper, C. (Charles), Gillman, M.H. (Matthew), Hocher, B. (Berthold), Mohlke, K.L. (Karen), Dedoussis, G.V. (George), Ong, K.K. (Ken), Pearson, E. (Ewan), Price, T.S. (Thomas), Power, C. (Christopher), Raitakari, O. (Olli), Saw, S-M. (Seang-Mei), Scherag, A. (Andre), Simell, O. (Olli), Sørensen, T.I.A. (Thorkild), and Wilson, J.F. (James)
Abstract: During aging, intracranial volume remains unchanged and represents maximally attained brain size, while various interacting biological phenomena lead to brain volume loss. Consequently, intracranial volume and brain volume in late life reflect different genetic influences. Our genome-wide association study (GWAS) in 8,175 community-dwelling elderly persons did not reveal any associations at genome-wide significance (P < 5 × 10 -8) for brain volume. In contrast, intracranial volume was significantly associated with two loci: rs4273712 (P = 3.4 × 10 -11), a known height-associated locus on chromosome 6q22, and rs9915547 (P = 1.5 × 10 -12), localized to the inversion on chromosome 17q21. We replicated the associations of these loci with intracranial volume in a separate sample of 1,752 elderly persons (P = 1.1 × 10 -3 for 6q22 and 1.2 × 10 -3 for 17q21). Furthermore, we also found suggestive associations of the 17q21 locus with head circumference in 10,768 children (mean age of 14.5 months). Our data identify two loci associated with head size, with the inversion at 17q21 also likely to be involved in attaining maximal brain size.
Published: 2012
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23. Recommendations for standardization and phenotype definitions in genetic studies of osteoarthritis: The TREAT-OA consortium

Author: Kerkhof, J.M. (Hanneke), Meulenbelt, I. (Ingrid), Akune, T. (Toru), Arden, N.K. (Nigel), Aromaa, A. (Arpo), Bierma-Zeinstra, S.M. (Sita), Cooper, C. (Charles), Dai, J., Doherty, M. (Michael), Doherty, S. (Sally), Felson, D., Gonzalez, A. (Antonio), Gordon, A., Harilainen, A. (Arsi), Hart, D.J., Hauksson, V.B. (Valdimar), Heliovaara, M. (Markku), Hofman, A. (Albert), Ikegawa, S., Ingvarsson, T. (Torvaldur), Jiang, Q., Jonsson, H., Jonsdottir, I. (Ingileif), Kawaguchi, H., Kloppenburg, M. (Margreet), Kujala, U.M. (Urho), Lane, N.E., Leino-Arjas, P. (Päivi I.), Lohmander, L.S. (Stefan), Luyten, F.P. (Frank), Malizos, K.N. (Konstantinos), Nakajima, M., Nevitt, M.C. (Michael), Pols, H.A.P. (Huib), Rivadeneira Ramirez, F. (Fernando), Shi, D., Slagboom, P.E. (Eline), Spector, T.D. (Timothy), Stefansson, K. (Kari), Sudo, A. (Akihiro), Tamm, A., Tamm, A.E. (Aile), Tsezou, A. (Aspasia), Uchida, A., Uitterlinden, A.G. (André), Wilkinson, J.M. (Mark), Yoshimura, N., Valdes, A.M. (Ana Maria), Meurs, J.B.J. (Joyce) van, Carr, A.J. (Andrew Jonathan), Kerkhof, J.M. (Hanneke), Meulenbelt, I. (Ingrid), Akune, T. (Toru), Arden, N.K. (Nigel), Aromaa, A. (Arpo), Bierma-Zeinstra, S.M. (Sita), Cooper, C. (Charles), Dai, J., Doherty, M. (Michael), Doherty, S. (Sally), Felson, D., Gonzalez, A. (Antonio), Gordon, A., Harilainen, A. (Arsi), Hart, D.J., Hauksson, V.B. (Valdimar), Heliovaara, M. (Markku), Hofman, A. (Albert), Ikegawa, S., Ingvarsson, T. (Torvaldur), Jiang, Q., Jonsson, H., Jonsdottir, I. (Ingileif), Kawaguchi, H., Kloppenburg, M. (Margreet), Kujala, U.M. (Urho), Lane, N.E., Leino-Arjas, P. (Päivi I.), Lohmander, L.S. (Stefan), Luyten, F.P. (Frank), Malizos, K.N. (Konstantinos), Nakajima, M., Nevitt, M.C. (Michael), Pols, H.A.P. (Huib), Rivadeneira Ramirez, F. (Fernando), Shi, D., Slagboom, P.E. (Eline), Spector, T.D. (Timothy), Stefansson, K. (Kari), Sudo, A. (Akihiro), Tamm, A., Tamm, A.E. (Aile), Tsezou, A. (Aspasia), Uchida, A., Uitterlinden, A.G. (André), Wilkinson, J.M. (Mark), Yoshimura, N., Valdes, A.M. (Ana Maria), Meurs, J.B.J. (Joyce) van, and Carr, A.J. (Andrew Jonathan)
Abstract: Objective: To address the need for standardization of osteoarthritis (OA) phenotypes by examining the effect of heterogeneity among symptomatic (SOA) and radiographic osteoarthritis (ROA) phenotypes. Methods: Descriptions of OA phenotypes of the 28 studies involved in the TREAT-OA consortium were collected. We investigated whether different OA definitions result in different association results by creating various hip OA definitions in one large population based cohort (the Rotterdam Study I
Published: 2011
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24. Use of proton pump inhibitors and risk of hip/femur fracture: a population-based case-control study

Author: Pouwels, S. (Sander), Lalmohamed, A. (Arief), Souverein, P. (Patrick), Cooper, C. (Charles), Veldt, B.J. (Bart), Leufkens, H.G.M. (Hubert), Boer, A.C. (Anton) de, Staa, T.P. (Tjeerd) van, Vries, F. (Frank) de, Pouwels, S. (Sander), Lalmohamed, A. (Arief), Souverein, P. (Patrick), Cooper, C. (Charles), Veldt, B.J. (Bart), Leufkens, H.G.M. (Hubert), Boer, A.C. (Anton) de, Staa, T.P. (Tjeerd) van, and Vries, F. (Frank) de
Abstract: Summary: Previous studies evaluated the association between proton pump inhibitor (PPI) use and subsequent fracture risk, but they showed ambiguous results. Therefore, the objective was to evaluate this association in a different study population. Our findings show that there is probably no causal relationship between PPI use and hip fracture risk. Introduction: Previous studies evaluated the association between PPI use and subsequent fracture risk, but they showed ambiguous results. To further test these conflicting results, the objective of this study was to evaluate the association between the use of PPIs and the risk of hip/femur fracture in a different study population. Methods: A case-control study was conducted using data from the Dutch PHARMO record linkage system. The study population included 6,763 cases aged 18 years and older with a first hip/femur fracture during enrolment and 26,341 age-, gender- and region-matched controls. Results: Current users of PPIs had an increased risk of hip/femur fracture yielding an adjusted odds ratio (AOR) of 1.20 (95% CI 1.04-1.40). Fracture risk attenuated with increasing durations of use, resulting in AORs of 1.26 (95% CI 0.94-1.68) in the first 3 months, 1.31 (95% CI 0.97-1.75) between 3 and 12 months, 1.18 (95% CI 0.92-1.52) between 13 and 36 months and 1.09 (95% CI 0.81-1.47) for use longer than 36 months. Conclusion: Our findings show that there is probably no causal relationship between PPI use and hip fracture risk. The observed association may be the result of unmeasured distortions: although current use of PPIs was associated with a 1.2-fold increased risk of hip/femur fracture, the positive association was attenuated with longer durations of continuous use. Our findings do not support that discontinuation of PPIs decreases risk of hip frac
Published: 2011
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25. Genome-wide association scan meta-analysis identifies three loci influencing adiposity and fat distribution

Author: Lindgren, C.M. (Cecilia), Heid, I.M. (Iris), Randall, J.C. (Joshua), Lamina, C. (Claudia), Steinthorsdottir, V. (Valgerdur), Qi, L. (Lu), Speliotes, E.K. (Elizabeth), Thorleifsson, G. (Gudmar), Willer, C.J. (Cristen), Herrera, B.M. (Blanca), Jackson, A.U. (Anne), Lim, N. (Noha), Scheet, P. (Paul), Soranzo, N. (Nicole), Amin, N. (Najaf), Aulchenko, Y.S. (Yurii), Chambers, J.C. (John), Drong, A. (Alexander), Luan, J., Lyon, H.N. (Helen), Rivadeneira Ramirez, F. (Fernando), Sanna, S. (Serena), Timpson, N.J. (Nicholas), Zillikens, M.C. (Carola), Jing, H.Z., Almgren, P. (Peter), Bandinelli, S. (Stefania), Bennett, A.J. (Amanda), Bergman, R.N. (Richard), Bonnycastle, L.L. (Lori), Bumpstead, S. (Suzannah), Chanock, S.J. (Stephen), Cherkas, L. (Lynn), Chines, P.S. (Peter), Coin, L. (Lachlan), Cooper, C. (Charles), Crawford, G. (Gabe), Doering, A. (Angela), Dominiczak, A. (Anna), Doney, A.S.F. (Alex), Ebrahim, S. (Shanil), Elliott, P. (Paul), Erdos, M.R. (Michael), Estrada Gil, K. (Karol), Ferrucci, L. (Luigi), Fischer, G. (Guido), Forouhi, N.G. (Nita), Gieger, C. (Christian), Grallert, H. (Harald), Groves, C.J. (Christopher), Grundy, S.M. (Scott), Guiducci, C. (Candace), Hadley, D. (David), Hamsten, A. (Anders), Havulinna, A.S. (Aki), Hofman, A. (Albert), Holle, R. (Rolf), Holloway, J.W. (John), Illig, T. (Thomas), Isomaa, B. (Bo), Jacobs, L.C. (Leonie), Jameson, K. (Karen), Jousilahti, P. (Pekka), Karpe, F. (Fredrik), Kuusisto, J. (Johanna), Laitinen, J. (Jaana), Lathrop, G.M. (Mark), Lawlor, D.A. (Debbie), Mangino, M. (Massimo), McArdle, W.L. (Wendy), Meitinger, T. (Thomas), Morken, M.A. (Mario), Morris, A.P. (Andrew), Munroe, P. (Patricia), Narisu, N. (Narisu), Nordström, A. (Anna), Oostra, B.A. (Ben), Palmer, C.N.A. (Colin), Payne, F. (Felicity), Peden, J. (John), Prokopenko, I. (Inga), Renström, F. (Frida), Ruokonen, A. (Aimo), Salomaa, V. (Veikko), Sandhu, M.S. (Manjinder), Scott, L.J. (Laura), Scuteri, A. (Angelo), Silander, K. (Kaisa), Song, K. (Kijoung), Yuan, X. (Xin), Stringham, H.M. (Heather), Swift, A.J. (Amy), Tuomi, T. (Tiinamaija), Uda, M. (Manuela), Vollenweider, P. (Peter), Waeber, G. (Gérard), Wallace, C. (Chris), Walters, G.B. (Bragi), Weedon, M.N. (Michael), Witteman, J.C.M. (Jacqueline), Zhang, C. (Cuilin), Caulfield, M. (Mark), Collins, F.S. (Francis), Smith, A.V. (Davey), Day, I.N.M. (Ian), Franks, P.W. (Paul), Hattersley, A.T. (Andrew), Hu, F.B. (Frank), Jarvelin, M.-R. (Marjo-Riitta), Kong, A. (Augustine), Kooner, J.S. (Jaspal), Laakso, M. (Markku), Lakatta, E. (Edward), Mooser, V. (Vincent), Peltonen, L. (Leena Johanna), Samani, N.J. (Nilesh), Spector, T.D. (Timothy), Strachan, D.P. (David), Tanaka, T. (Toshiko), Tuomilehto, J. (Jaakko), Uitterlinden, A.G. (André), Tikka-Kleemola, P. (Päivi), Wareham, N.J. (Nick), Watkins, H. (Hugh), Waterworth, D. (Dawn), Boehnke, M. (Michael), Deloukas, P. (Panagiotis), Groop, L. (Leif), Hunter, D.J. (David), Thorsteinsdottir, U. (Unnur), Schlessinger, D. (David), Wichmann, H.E. (Erich), Frayling, T.M. (Timothy), Abecasis, G.R. (Gonçalo), Hirschhorn, J.N. (Joel), Loos, R.J.F. (Ruth), Zwart, J-A. (John-Anker), Mohlke, K.L. (Karen), Barroso, I.E. (Inês), McCarthy, M.I. (Mark), Lindgren, C.M. (Cecilia), Heid, I.M. (Iris), Randall, J.C. (Joshua), Lamina, C. (Claudia), Steinthorsdottir, V. (Valgerdur), Qi, L. (Lu), Speliotes, E.K. (Elizabeth), Thorleifsson, G. (Gudmar), Willer, C.J. (Cristen), Herrera, B.M. (Blanca), Jackson, A.U. (Anne), Lim, N. (Noha), Scheet, P. (Paul), Soranzo, N. (Nicole), Amin, N. (Najaf), Aulchenko, Y.S. (Yurii), Chambers, J.C. (John), Drong, A. (Alexander), Luan, J., Lyon, H.N. (Helen), Rivadeneira Ramirez, F. (Fernando), Sanna, S. (Serena), Timpson, N.J. (Nicholas), Zillikens, M.C. (Carola), Jing, H.Z., Almgren, P. (Peter), Bandinelli, S. (Stefania), Bennett, A.J. (Amanda), Bergman, R.N. (Richard), Bonnycastle, L.L. (Lori), Bumpstead, S. (Suzannah), Chanock, S.J. (Stephen), Cherkas, L. (Lynn), Chines, P.S. (Peter), Coin, L. (Lachlan), Cooper, C. (Charles), Crawford, G. (Gabe), Doering, A. (Angela), Dominiczak, A. (Anna), Doney, A.S.F. (Alex), Ebrahim, S. (Shanil), Elliott, P. (Paul), Erdos, M.R. (Michael), Estrada Gil, K. (Karol), Ferrucci, L. (Luigi), Fischer, G. (Guido), Forouhi, N.G. (Nita), Gieger, C. (Christian), Grallert, H. (Harald), Groves, C.J. (Christopher), Grundy, S.M. (Scott), Guiducci, C. (Candace), Hadley, D. (David), Hamsten, A. (Anders), Havulinna, A.S. (Aki), Hofman, A. (Albert), Holle, R. (Rolf), Holloway, J.W. (John), Illig, T. (Thomas), Isomaa, B. (Bo), Jacobs, L.C. (Leonie), Jameson, K. (Karen), Jousilahti, P. (Pekka), Karpe, F. (Fredrik), Kuusisto, J. (Johanna), Laitinen, J. (Jaana), Lathrop, G.M. (Mark), Lawlor, D.A. (Debbie), Mangino, M. (Massimo), McArdle, W.L. (Wendy), Meitinger, T. (Thomas), Morken, M.A. (Mario), Morris, A.P. (Andrew), Munroe, P. (Patricia), Narisu, N. (Narisu), Nordström, A. (Anna), Oostra, B.A. (Ben), Palmer, C.N.A. (Colin), Payne, F. (Felicity), Peden, J. (John), Prokopenko, I. (Inga), Renström, F. (Frida), Ruokonen, A. (Aimo), Salomaa, V. (Veikko), Sandhu, M.S. (Manjinder), Scott, L.J. (Laura), Scuteri, A. (Angelo), Silander, K. (Kaisa), Song, K. (Kijoung), Yuan, X. (Xin), Stringham, H.M. (Heather), Swift, A.J. (Amy), Tuomi, T. (Tiinamaija), Uda, M. (Manuela), Vollenweider, P. (Peter), Waeber, G. (Gérard), Wallace, C. (Chris), Walters, G.B. (Bragi), Weedon, M.N. (Michael), Witteman, J.C.M. (Jacqueline), Zhang, C. (Cuilin), Caulfield, M. (Mark), Collins, F.S. (Francis), Smith, A.V. (Davey), Day, I.N.M. (Ian), Franks, P.W. (Paul), Hattersley, A.T. (Andrew), Hu, F.B. (Frank), Jarvelin, M.-R. (Marjo-Riitta), Kong, A. (Augustine), Kooner, J.S. (Jaspal), Laakso, M. (Markku), Lakatta, E. (Edward), Mooser, V. (Vincent), Peltonen, L. (Leena Johanna), Samani, N.J. (Nilesh), Spector, T.D. (Timothy), Strachan, D.P. (David), Tanaka, T. (Toshiko), Tuomilehto, J. (Jaakko), Uitterlinden, A.G. (André), Tikka-Kleemola, P. (Päivi), Wareham, N.J. (Nick), Watkins, H. (Hugh), Waterworth, D. (Dawn), Boehnke, M. (Michael), Deloukas, P. (Panagiotis), Groop, L. (Leif), Hunter, D.J. (David), Thorsteinsdottir, U. (Unnur), Schlessinger, D. (David), Wichmann, H.E. (Erich), Frayling, T.M. (Timothy), Abecasis, G.R. (Gonçalo), Hirschhorn, J.N. (Joel), Loos, R.J.F. (Ruth), Zwart, J-A. (John-Anker), Mohlke, K.L. (Karen), Barroso, I.E. (Inês), and McCarthy, M.I. (Mark)
Abstract: To identify genetic loci influencing central obesity and fat distribution, we performed a meta-analysis of 16 genome-wide association studies (GWAS, N = 38,580) informative for adult waist circumference (WC) and waist-hip ratio (WHR). We selected 26 SNPs for follow-up, for which the evidence of association with measures of central adiposity (WC and/or WHR) was strong and disproportionate to that for overall adiposity or height. Follow-up studies in a maximum of 70,689 individuals identified two loci strongly associated with measures of central adiposity; these map near TFAP2B (WC, P = 1.9×102-11) and MSRA (WC, P = 8.9×10-9). A third locus, near LYPLAL1, was associated with WHR in women only (P = 2.6×10-8). The variants near TFAP2B appear to influence central adiposity through an effect on overall obesity/fat-mass, whereas LYPLAL1 displays a strong female-only association with fat distribution. By focusing on anthropometric measures of central obesity and fat distribution, we have identified three loci implicated in the regulation of human
Published: 2009
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26. Six new loci associated with body mass index highlight a neuronal influence on body weight regulation

Author: Willer, C.J. (Cristen), Speliotes, E.K. (Elizabeth), Loos, R.J.F. (Ruth), Li, S. (Shengxu), Lindgren, C.M. (Cecilia), Heid, I.M. (Iris), Berndt, S.I. (Sonja), Elliott, A.L. (Amanda), Jackson, A.U. (Anne), Lamina, C. (Claudia), Lettre, G. (Guillaume), Lim, N. (Noha), Lyon, H.N. (Helen), McCarroll, S.A. (Steven), Papadakis, K. (Konstantinos), Qi, L. (Lu), Randall, J.C. (Joshua), Roccasecca, R.M., Sanna, S. (Serena), Scheet, P. (Paul), Weedon, M.N. (Michael), Wheeler, E. (Eleanor), Zhao, J.H. (Jing Hua), Jacobs, L.C. (Leonie), Prokopenko, I. (Inga), Soranzo, N. (Nicole), Tanaka, T. (Toshiko), Timpson, N.J. (Nicholas), Almgren, P. (Peter), Bennett, A.J. (Amanda), Bergman, R.N. (Richard), Bingham, S. (Sheila), Bonnycastle, L.L. (Lori), Brown, M.J. (Morris), Burtt, N.P. (Noël), Chines, P.S. (Peter), Coin, L. (Lachlan), Collins, F.S. (Francis), Connell, J. (John), Cooper, C. (Charles), Smith, A.V. (Davey), Dennison, E.M. (Elaine), Deodhar, P. (Parimal), Erdos, M.R. (Michael), Estrada Gil, K. (Karol), Evans, D.M. (David), Gianniny, L. (Lauren), Gieger, C. (Christian), Gillson, C.J. (Christopher), Guiducci, C. (Candace), Hackett, R. (Rachel), Hadley, D. (David), Hall, A.S. (Alistair), Havulinna, A.S. (Aki), Hebebrand, J. (Johannes), Hofman, A. (Albert), Isomaa, B. (Bo), Johnson, T. (Toby), Jousilahti, P. (Pekka), Jovanovic, Z. (Zorica), Khaw, K-T. (Kay-Tee), Kraft, P. (Peter), Kuokkanen, M. (Mikko), Kuusisto, J. (Johanna), Laitinen, J. (Jaana), Lakatta, E. (Edward), Luan, J., Luben, R.N. (Robert), Mangino, M. (Massimo), McArdle, W.L. (Wendy), Meitinger, T. (Thomas), Mulas, A. (Antonella), Munroe, P. (Patricia), Narisu, N. (Narisu), Ness, A.R. (Andrew), Northstone, K. (Kate), O'Rahilly, S. (Stephen), Purmann, C. (Carolin), Rees, M.G. (Matthew), Ridderstråle, M. (Martin), Ring, S.M. (Susan), Rivadeneira Ramirez, F. (Fernando), Ruokonen, A. (Aimo), Sandhu, M.S. (Manjinder), Saramies, J. (Jouko), Scott, L.J. (Laura), Scuteri, A. (Angelo), Silander, K. (Kaisa), Sims, M.A. (Matthew), Song, K. (Kijoung), Stephens, J. (Jonathan), Stevens, S. (Suzanne), Stringham, H.M. (Heather), Tung, Y.C.L. (Loraine), Valle, T.T. (Timo), Tikka-Kleemola, P. (Päivi), Vimaleswaran, K.S. (Karani), Vollenweider, P. (Peter), Waeber, G. (Gérard), Wallace, C. (Chris), Watanabe, R.M. (Richard), Waterworth, D. (Dawn), Watkins, N. (Nicholas), Witteman, J.C.M. (Jacqueline), Zeggini, E. (Eleftheria), Zhai, G. (Guangju), Zillikens, M.C. (Carola), Altshuler, D. (David), Caulfield, M. (Mark), Chanock, S.J. (Stephen), Farooqi, I.S. (Sadaf), Ferrucci, L. (Luigi), Guralnik, J.M. (Jack), Hattersley, A.T. (Andrew), Hu, F.B. (Frank), Jarvelin, M.-R. (Marjo-Riitta), Laakso, M. (Markku), Mooser, V. (Vincent), Ong, K.K. (Ken), Ouwehand, W.H. (Willem), Salomaa, V. (Veikko), Samani, N.J. (Nilesh), Spector, T.D. (Timothy), Tuomi, T. (Tiinamaija), Tuomilehto, J. (Jaakko), Uda, M. (Manuela), Uitterlinden, A.G. (André), Deloukas, P. (Panagiotis), Wareham, N.J. (Nick), Frayling, T.M. (Timothy), Groop, L. (Leif), Hayes, R.B. (Richard), Hunter, D. (David), Mohlke, K.L. (Karen), Peltonen, L. (Leena Johanna), Schlessinger, D. (David), Strachan, D.P. (David), Wichmann, H.E. (Erich), McCarthy, M.I. (Mark), Boehnke, M. (Michael), Barroso, I.E. (Inês), Abecasis, G.R. (Gonçalo), Hirschhorn, J.N. (Joel), Willer, C.J. (Cristen), Speliotes, E.K. (Elizabeth), Loos, R.J.F. (Ruth), Li, S. (Shengxu), Lindgren, C.M. (Cecilia), Heid, I.M. (Iris), Berndt, S.I. (Sonja), Elliott, A.L. (Amanda), Jackson, A.U. (Anne), Lamina, C. (Claudia), Lettre, G. (Guillaume), Lim, N. (Noha), Lyon, H.N. (Helen), McCarroll, S.A. (Steven), Papadakis, K. (Konstantinos), Qi, L. (Lu), Randall, J.C. (Joshua), Roccasecca, R.M., Sanna, S. (Serena), Scheet, P. (Paul), Weedon, M.N. (Michael), Wheeler, E. (Eleanor), Zhao, J.H. (Jing Hua), Jacobs, L.C. (Leonie), Prokopenko, I. (Inga), Soranzo, N. (Nicole), Tanaka, T. (Toshiko), Timpson, N.J. (Nicholas), Almgren, P. (Peter), Bennett, A.J. (Amanda), Bergman, R.N. (Richard), Bingham, S. (Sheila), Bonnycastle, L.L. (Lori), Brown, M.J. (Morris), Burtt, N.P. (Noël), Chines, P.S. (Peter), Coin, L. (Lachlan), Collins, F.S. (Francis), Connell, J. (John), Cooper, C. (Charles), Smith, A.V. (Davey), Dennison, E.M. (Elaine), Deodhar, P. (Parimal), Erdos, M.R. (Michael), Estrada Gil, K. (Karol), Evans, D.M. (David), Gianniny, L. (Lauren), Gieger, C. (Christian), Gillson, C.J. (Christopher), Guiducci, C. (Candace), Hackett, R. (Rachel), Hadley, D. (David), Hall, A.S. (Alistair), Havulinna, A.S. (Aki), Hebebrand, J. (Johannes), Hofman, A. (Albert), Isomaa, B. (Bo), Johnson, T. (Toby), Jousilahti, P. (Pekka), Jovanovic, Z. (Zorica), Khaw, K-T. (Kay-Tee), Kraft, P. (Peter), Kuokkanen, M. (Mikko), Kuusisto, J. (Johanna), Laitinen, J. (Jaana), Lakatta, E. (Edward), Luan, J., Luben, R.N. (Robert), Mangino, M. (Massimo), McArdle, W.L. (Wendy), Meitinger, T. (Thomas), Mulas, A. (Antonella), Munroe, P. (Patricia), Narisu, N. (Narisu), Ness, A.R. (Andrew), Northstone, K. (Kate), O'Rahilly, S. (Stephen), Purmann, C. (Carolin), Rees, M.G. (Matthew), Ridderstråle, M. (Martin), Ring, S.M. (Susan), Rivadeneira Ramirez, F. (Fernando), Ruokonen, A. (Aimo), Sandhu, M.S. (Manjinder), Saramies, J. (Jouko), Scott, L.J. (Laura), Scuteri, A. (Angelo), Silander, K. (Kaisa), Sims, M.A. (Matthew), Song, K. (Kijoung), Stephens, J. (Jonathan), Stevens, S. (Suzanne), Stringham, H.M. (Heather), Tung, Y.C.L. (Loraine), Valle, T.T. (Timo), Tikka-Kleemola, P. (Päivi), Vimaleswaran, K.S. (Karani), Vollenweider, P. (Peter), Waeber, G. (Gérard), Wallace, C. (Chris), Watanabe, R.M. (Richard), Waterworth, D. (Dawn), Watkins, N. (Nicholas), Witteman, J.C.M. (Jacqueline), Zeggini, E. (Eleftheria), Zhai, G. (Guangju), Zillikens, M.C. (Carola), Altshuler, D. (David), Caulfield, M. (Mark), Chanock, S.J. (Stephen), Farooqi, I.S. (Sadaf), Ferrucci, L. (Luigi), Guralnik, J.M. (Jack), Hattersley, A.T. (Andrew), Hu, F.B. (Frank), Jarvelin, M.-R. (Marjo-Riitta), Laakso, M. (Markku), Mooser, V. (Vincent), Ong, K.K. (Ken), Ouwehand, W.H. (Willem), Salomaa, V. (Veikko), Samani, N.J. (Nilesh), Spector, T.D. (Timothy), Tuomi, T. (Tiinamaija), Tuomilehto, J. (Jaakko), Uda, M. (Manuela), Uitterlinden, A.G. (André), Deloukas, P. (Panagiotis), Wareham, N.J. (Nick), Frayling, T.M. (Timothy), Groop, L. (Leif), Hayes, R.B. (Richard), Hunter, D. (David), Mohlke, K.L. (Karen), Peltonen, L. (Leena Johanna), Schlessinger, D. (David), Strachan, D.P. (David), Wichmann, H.E. (Erich), McCarthy, M.I. (Mark), Boehnke, M. (Michael), Barroso, I.E. (Inês), Abecasis, G.R. (Gonçalo), and Hirschhorn, J.N. (Joel)
Abstract: Common variants at only two loci, FTO and MC4R, have been reproducibly associated with body mass index (BMI) in humans. To identify additional loci, we conducted meta-analysis of 15 genome-wide association studies for BMI (n > 32,000) and followed up top signals in 14 additional cohorts (n > 59,000). We strongly confirm FTO and MC4R and identify six additional loci (P < 5 × 10-8): TMEM18, KCTD15, GNPDA2, SH2B1, MTCH2 and NEGR1 (where a 45-kb deletion polymorphism is a candidate causal variant). Several of the likely causal genes are highly expressed or known to act in the central nervous system (CNS), emphasizing, as in rare monogenic forms of obesity, the role of the CNS in predisposition to obesity.
Published: 2009
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27. Technology and industrial competitiveness in developing countries

Author: Cooper, C. (Charles) and Cooper, C. (Charles)
Abstract: Technological change engages our attention. I suspect that even those who believe themselves to be essentially ignorant about technology - and perhaps not very interested in it - nevertheless experience,. from time to time, a sense of wonder at the extraordinary things which new technologies are able to do. Perhaps we are as bewitched by technology, and nearly as convinced of its omnipotence as were the Europeans of the last years of the nineteenth century.
Published: 1995

28. Learning-by-doing in an open economy: version of the Feldman model

Author: Cooper, C. (Charles) and Cooper, C. (Charles)
Published: 1984

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28 results on '"Cooper, C. (Charles)"'

1. Associations of maternal dietary inflammatory potential and quality with offspring birth outcomes: An individual participant data pooled analysis of 7 European cohorts in the ALPHABET consortium

2. Development of a polygenic risk score to improve screening for fracture risk: A genetic risk prediction study

3. Development of a polygenic risk score to improve screening for fracture risk: A genetic risk prediction study

4. Repositioning of the global epicentre of non-optimal cholesterol

5. Falls in older aged adults in 22 European countries: Incidence, mortality and burden of disease from 1990 to 2017

6. Deriving the dietary approaches to stop hypertension (DASH) score in women from seven pregnancy cohorts from the European alphabet consortium

7. The global burden of falls: Global, regional and national estimates of morbidity and mortality from the Global Burden of Disease Study 2017

8. Diagnosis and Management of Paget's Disease of Bone in Adults: A Clinical Guideline

9. Evidence for three genetic loci involved in both anorexia nervosa risk and variation of body mass index

10. International Osteoporosis Foundation and European Calcified Tissue Society Working Group. Recommendations for the screening of adherence to oral bisphosphonates

11. Identification of 153 new loci associated with heel bone mineral density and functional involvement of GPC6 in osteoporosis

12. Worldwide trends in diabetes since 1980: A pooled analysis of 751 population-based studies with 4.4 million participants

13. A century of trends in adult human height

14. Trends in adult body-mass index in 200 countries from 1975 to 2014: A pooled analysis of 1698 population-based measurement studies with 19.2 million participants

15. Genetic sharing with cardiovascular disease risk factors and diabetes reveals novel bone mineral density loci

16. Global, regional, and national incidence and mortality for HIV, tuberculosis, and malaria during 1990-2013: a systematic analysis for the Global Burden of Disease Study 2013

17. A genome-wide copy number association study of osteoporotic fractures points to the 6p25.1 locus

18. A reference case for economic evaluations in osteoarthritis: An expert consensus article from the European Society for Clinical and Economic Aspects of Osteoporosis and Osteoarthritis (ESCEO)

19. Health economics in the field of osteoarthritis: An Expert's consensus paper from the European Society for Clinical and Economic Aspects of Osteoporosis and Osteoarthritis (ESCEO)

20. Genome-wide association study meta-analysis of chronic widespread pain: Evidence for involvement of the 5p15.2 region

21. Genome-wide meta-analysis identifies 56 bone mineral density loci and reveals 14 loci associated with risk of fracture

22. Common variants at 6q22 and 17q21 are associated with intracranial volume

23. Recommendations for standardization and phenotype definitions in genetic studies of osteoarthritis: The TREAT-OA consortium

24. Use of proton pump inhibitors and risk of hip/femur fracture: a population-based case-control study

25. Genome-wide association scan meta-analysis identifies three loci influencing adiposity and fat distribution

26. Six new loci associated with body mass index highlight a neuronal influence on body weight regulation

27. Technology and industrial competitiveness in developing countries

28. Learning-by-doing in an open economy: version of the Feldman model

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28 results on '"Cooper, C. (Charles)"'

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