Search

Your search keyword '"Cooper, C. James"' showing total 6 results
Start Over Author "Cooper, C. James"
6 results on '"Cooper, C. James"'

5. Bringing together knowledge and maths.

Author

Cooper, C. James

Subjects
MATHEMATICS, KNOWLEDGE management, COMPUTER software industry, ENGINEERING, TECHNOLOGY
Abstract

This article focuses on the universal language of mathematics which underpins efforts to integrate knowledge from different domains. Motherhood elements will continue to support the growing user-base and make the powerful technology more accessible and useful across all industrial segments. Time pressures in industry increase every year, and the ability to quickly obtain all of the benefits of a software is often determined by how easy is it to configure the system to the science and domain of the industry. Historically, software vendors have responded with large, complex, and expensive vertical market design software that is tied in to a monolithic proprietary platform. Scientific frameworks like mechatronics and multiphysics are challenging the traditional parochial view of the engineering disciplines. The range of engineering information and knowledge is significantly more complex than typical business information, and the true collaborative leverage points of the engineering Web are only beginning to be identified.

Published
2004

6. IL-27 expression regulation and its effects on adaptive immunity against viruses.

Author

Andres-Martin F, James C, and Catalfamo M

Subjects
Humans, Animals, Gene Expression Regulation, Interleukin-27 metabolism, Viruses immunology, Interleukins immunology, Interleukins metabolism, Adaptive Immunity, Virus Diseases immunology
Abstract

IL-27, a member of the IL-6/IL-12 cytokine superfamily, is primarily secreted by antigen presenting cells, specifically by dendric cells, macrophages and B cells. IL-27 has antiviral activities and modulates both innate and adaptive immune responses against viruses. The role of IL-27 in the setting of viral infections is not well defined and both pro-inflammatory and anti-inflammatory functions have been described. Here, we discuss the latest advancements in the role of IL-27 in several viral infection models of human disease. We highlight important aspects of IL-27 expression regulation, the critical cell sources at different stages of the infection and their impact in cell mediated immunity. Lastly, we discuss the need to better define the antiviral and modulatory (pro-inflammatory vs anti-inflammatory) properties of IL-27 in the context of human chronic viral infections., Competing Interests: The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest., (Copyright © 2024 Andres-Martin, James and Catalfamo.)

Published
2024
Full Text
View/download PDF

Catalog

Books, media, physical & digital resources
See catalog results