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1. MASK-air: An OECD (Organisation for Economic Co-operation and Development) Best Practice for Public Health on Integrated Care for Chronic Diseases

Author

Czarlewski, Wienczyslawa, Haahtela, Tari, Canonica, G. Walter, Costa, Elisio M., Klimek, Ludger, Kuna, Piotr, Kupczyk, Maciej, Kvedariene, Violeta, Kulus, Marek, Larenas-Linnemann, Désirée E., Louis, Renaud, Pfaar, Oliver, Papadopoulos, Nikolaos G., Pham-Thi, Nhân, Regateiro, Frederico S., Roche, Nicolas, Samolinski, Boleslaw, Sastre, Joaquin, Scichilone, Nicola, Taborda-Barata, Luis, Valiulis, Arunas, Yorgancioglu, Arzu, Ventura, Maria Teresa, Almeida, Rute, Amaral, Rita, Ansotegui, Ignacio J., Bergmann, Karl C., Bosnic-Anticevich, Sinthia, Braido, Fulvio, Brussino, Luisa, Cardona, Victoria, Cecchi, Lorenzo, Loureiro, Claudia Chaves, Cingi, Cemal, Cruz, Alvaro A., Fokkens, Wytske J., de Vries, Govert, Gemicioglu, Bilun, Giuliano, Antonio F.M., Linuma, Tomohisa, Ivancevich, Juan Carlos, Jácome, Cristina, Kaidashev, Igor, Kraxner, Helga, Laune, Daniel, Louis, Gilles, Lourenço, Olga, Makela, Mika, Makris, Michael, Morais-Almeida, Mario, Mösges, Ralph, Maurer, Marcus, Mullol, Joaquim, Nadif, Rachel, Niedoszytko, Marek, O’Hehir, Robyn, Okamoto, Yoshitaka, Ollert, Markus, Olze, Heidi, Patella, Vincenzo, Pétré, Benoit, Puggioni, Francesca, Romantowski, Jan, Rouadi, Philip W., Reitsma, Sietze, Rivero-Yeverino, Daniela, Rodriguez-Gonzalez, Monica, Sá-Sousa, Ana, Savouré, Marine, Serpa, Faradiba S., Shamji, Mohamed H., Sheikh, Aziz, Ulrik, Charlotte Suppli, Sofiev, Mikhail, Sova, Milan, Sperl, Annette, Todo-Bom, Ana, Tomazic, Peter V., Toppila-Salmi, Sanna, Tsiligianni, Ioanna, Valovirta, Erkka, van Eerd, Michiel, Zidarn, Mihaela, Blain, Hubert, Boulet, Louis-Philippe, Brusselle, Guy, Buhl, Roland, Charpin, Denis, Casale, Thomas, Chivato, Tomas, Correia-de-Sousa, Jaime, Corrigan, Christopher, de Blay, Frédéric, Del Giacco, Stefano, Devillier, Philippe, Dykewicz, Mark, Fiocchi, Alessandro, Giovannini, Mattia, Jassem, Ewa, Jutel, Marek, Keil, Thomas, La Grutta, Stefania, Lipworth, Brian, Papi, Alberto, Pépin, Jean-Louis, Quirce, Santiago, Cordeiro, Carlos Robalo, Torres, Maria J., Usmani, Omar S., Bousquet, Jean, Sousa-Pinto, Bernardo, Anto, Josep M., Bedbrook, Anna, Fonseca, Joao A., and Zuberbier, Torsten

Published
2024
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2. Poor Rhinitis and Asthma Control Is Associated With Decreased Health-Related Quality of Life and Utilities: A MASK-air Study

Author

Czarlewski, Wienczyslawa, Bedbrook, Anna, Haahtela, Tari, Canonica, G. Walter, Costa, Elisio M., Kupczyk, Maciej, Kvedariene, Violeta, Kulus, Marek, Larenas-Linnemann, Désirée E., Pfaar, Oliver, Papadopoulos, Nikolaos G., Pham-Thi, Nhân, Regateiro, Frederico S., Roche, Nicolas, Sastre, Joaquin, Scichilone, Nicola, Taborda-Barata, Luis, Valiulis, Arunas, Yorgancioglu, Arzu, Ventura, Maria Teresa, Almeida, Rute, Amaral, Rita, Ansotegui, Ignacio J., Bergmann, Karl C., Bosnic-Anticevich, Sinthia, Braido, Fulvio, Brussino, Luisa, Cardona, Victoria, Cecchi, Lorenzo, Loureiro, Claudia Chaves, Cingi, Cemal, Cruz, Alvaro A., Fokkens, Wytske J., de Vries, Govert, Gemicioglu, Bilun, Giuliana, Antonio F.M., Linuma, Tomohisa, Ivancevich, Juan Carlos, Jácome, Cristina, Kaidashev, Igor, Kraxner, Helga, Laune, Daniel, Louis, Gilles, Lourenço, Olga, Makela, Mika, Makris, Michael, Mösges, Ralph, Maurer, Marcus, Mullol, Joaquim, Nadif, Rachel, Niedoszytko, Marek, O’Hehir, Robyn, Okamoto, Yoshitaka, Ollert, Markus, Olze, Heidi, Patella, Vincenzo, Pétré, Benoit, Puggioni, Francesca, Romantowski, Jan, Rouadi, Philip W., Reitsma, Sietze, Rivero-Yeverino, Daniela, Rodriguez-Gonzalez, Monica, Sá-Sousa, Ana, Serpa, Faradiba S., Shamji, Mohamed H., Sheikh, Aziz, Ulrik, Charlotte Suppli, Sofiev, Mikhail, Sova, Milan, Sperl, Annette, Todo-Bom, Ana, Tomazic, Peter V., Toppila-Salmi, Sanna, Tsiligianni, Ioanna, Valovirta, Erkka, van Eerd, Michiel, Zidarn, Mihaela, Blain, Hubert, Boulet, Louis-Philippe, Brusselle, Guy, Buhl, Roland, Charpin, Denis, Casale, Thomas, Chivato, Tomas, Correia-de-Sousa, Jaime, Corrigan, Christopher, de Blay, Frédéric, Del Giacco, Stefano, Devillier, Philippe, Dykewicz, Mark, Fiocchi, Alessandro, Giovannini, Mattia, Jassem, Ewa, Jutel, Marek, Keil, Thomas, La Grutta, Stefania, Lipworth, Brian, Papi, Alberto, Pépin, Jean-Louis, Quirce, Santiago, Cordeiro, Carlos Robalo, Torres, Maria J., Usmani, Omar S., Vieira, Rafael José, Leemann, Lucas, Briggs, Andrew, Pereira, Ana Margarida, Savouré, Marine, Kuna, Piotr, Morais-Almeida, Mário, Bewick, Michael, Azevedo, Luís Filipe, Louis, Renaud, Klimek, Ludger, Bahbah, Farah, Samolinski, Boleslaw, Anto, Josep M., Zuberbier, Torsten, Fonseca, João A., Bousquet, Jean, and Sousa-Pinto, Bernardo

Published
2024
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3. Safety and anti-tumour activity of the IgE antibody MOv18 in patients with advanced solid tumours expressing folate receptor-alpha: a phase I trial

Author

Spicer, James, Basu, Bristi, Montes, Ana, Banerji, Udai, Kristeleit, Rebecca, Miller, Rowan, Veal, Gareth J., Corrigan, Christopher J., Till, Stephen J., Figini, Mariangela, Canevari, Silvana, Barton, Claire, Jones, Paul, Mellor, Sarah, Carroll, Simon, Selkirk, Chris, Nintos, George, Kwatra, Vineet, Funingana, Ionut-Gabriel, Doherty, Gary, Gould, Hannah J., Pellizzari, Giulia, Nakamura, Mano, Ilieva, Kristina M., Khiabany, Atousa, Stavraka, Chara, Chauhan, Jitesh, Gillett, Cheryl, Pinder, Sarah, Bax, Heather J., Josephs, Debra H., and Karagiannis, Sophia N.

Published
2023
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4. Poor rhinitis and asthma control is associated with decreased health-related quality-of-life and utilities: A MASK-air study

Author

Vieira, Rafael José, primary, Leemann, Lucas, additional, Briggs, Andrew, additional, Pereira, Ana Margarida, additional, Savouré, Marine, additional, Kuna, Piotr, additional, Morais-Almeida, Mário, additional, Bewick, Michael, additional, Azevedo, Luís Filipe, additional, Louis, Renaud, additional, Klimek, Ludger, additional, Bahbah, Farah, additional, Samolinski, Boleslaw, additional, Anto, Josep M., additional, Zuberbier, Torsten, additional, Fonseca, João A., additional, Bousquet, Jean, additional, Sousa-Pinto, Bernardo, additional, Czarlewski, Wienczyslawa, additional, Bedbrook, Anna, additional, Haahtela, Tari, additional, Canonica, G Walter, additional, Costa, Elisio M., additional, Kupczyk, Maciej, additional, Kvedariene, Violeta, additional, Kulus, Marek, additional, Larenas-Linnemann, Désirée E., additional, Pfaar, Oliver, additional, Papadopoulos, Nikolaos G., additional, Pham-Thi, Nhân, additional, Regateiro, Frederico S., additional, Roche, Nicolas, additional, Sastre, Joaquin, additional, Scichilone, Nicola, additional, Taborda-Barata, Luis, additional, Valiulis, Arunas, additional, Yorgancioglu, Arzu, additional, Ventura, Maria Teresa, additional, Almeida, Rute, additional, Amaral, Rita, additional, Ansotegui, Ignacio J., additional, Bergmann, Karl C., additional, Bosnic-Anticevich, Sinthia, additional, Braido, Fulvio, additional, Brussino, Luisa, additional, Cardona, Victoria, additional, Cecchi, Lorenzo, additional, Loureiro, Claudia Chaves, additional, Cingi, Cemal, additional, Cruz, Alvaro A., additional, Fokkens, Wytske J., additional, de Vries, Govert, additional, Gemicioglu, Bilun, additional, Giuliana, Antonio FM., additional, Linuma, Tomohisa, additional, Ivancevich, Juan Carlos, additional, Jácome, Cristina, additional, Kaidashev, Igor, additional, Kraxner, Helga, additional, Laune, Daniel, additional, Louis, Gilles, additional, Lourenço, Olga, additional, Makela, Mika, additional, Makris, Michael, additional, Mösges, Ralph, additional, Maurer, Marcus, additional, Mullol, Joaquim, additional, Nadif, Rachel, additional, Niedoszytko, Marek, additional, O’Hehir, Robyn, additional, Okamoto, Yoshitaka, additional, Ollert, Markus, additional, Olze, Heidi, additional, Patella, Vincenzo, additional, Pétré, Benoit, additional, Puggioni, Francesca, additional, Romantowski, Jan, additional, Rouadi, Philip W., additional, Reitsma, Sietze, additional, Rivero-Yeverino, Daniela, additional, Rodriguez-Gonzalez, Monica, additional, Sá-Sousa, Ana, additional, Serpa, Faradiba S., additional, Shamji, Mohamed H., additional, Sheikh, Aziz, additional, Ulrik, Charlotte Suppli, additional, Sofiev, Mikhail, additional, Sova, Milan, additional, Sperl, Annette, additional, Todo-Bom, Ana, additional, Tomazic, Peter V., additional, Toppila-Salmi, Sanna, additional, Tsiligianni, Ioanna, additional, Valovirta, Erkka, additional, van Eerd, Michiel, additional, Zidarn, Mihaela, additional, Blain, Hubert, additional, Boulet, Louis-Philippe, additional, Brusselle, Guy, additional, Buhl, Roland, additional, Charpin, Denis, additional, Casale, Thomas, additional, Chivato, Tomas, additional, Correia-de-Sousa, Jaime, additional, Corrigan, Christopher, additional, de Blay, Frédéric, additional, Del Giacco, Stefano, additional, Devillier, Philippe, additional, Dykewicz, Mark, additional, Fiocchi, Alessandro, additional, Giovannini, Mattia, additional, Jassem, Ewa, additional, Jutel, Marek, additional, Keil, Thomas, additional, La Grutta, Stefania, additional, Lipworth, Brian, additional, Papi, Alberto, additional, Pépin, Jean-Louis, additional, Quirce, Santiago, additional, Cordeiro, Carlos Robalo, additional, Torres, Maria J., additional, and Usmani, Omar S., additional

Published
2024
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5. MASK-air®: An OECD (Organisation for Economic Coordination and Development) Best Practice for Public Health on integrated care for chronic diseases.

Author

Bousquet, Jean, primary, Sousa-Pinto, Bernardo, additional, Anto, Josep M., additional, Bedbrook, Anna, additional, Fonseca, Joao A., additional, Zuberbier, Torsten, additional, Czarlewski, Wienczyslawa, additional, Haahtela, Tari, additional, Canonica, G Walter, additional, Costa, Elisio M., additional, Klimek, Ludger, additional, Kuna, Piotr, additional, Kupczyk, Maciej, additional, Kvedariene, Violeta, additional, Kulus, Marek, additional, Larenas-Linnemann, Désirée E., additional, Louis, Renaud, additional, Pfaar, Oliver, additional, Papadopoulos, Nikolaos G., additional, Pham-Thi, Nhân, additional, Regateiro, Frederico S., additional, Roche, Nicolas, additional, Samolinski, Boleslaw, additional, Sastre, Joaquin, additional, Scichilone, Nicola, additional, Taborda-Barata, Luis, additional, Valiulis, Arunas, additional, Yorgancioglu, Arzu, additional, Ventura, Maria Teresa, additional, Almeida, Rute, additional, Amaral, Rita, additional, Ansotegui, Ignacio J., additional, Bergmann, Karl C., additional, Bosnic-Anticevich, Sinthia, additional, Braido, Fulvio, additional, Brussino, Luisa, additional, Cardona, Victoria, additional, Cecchi, Lorenzo, additional, Loureiro, Claudia Chaves, additional, Cingi, Cemal, additional, Cruz, Alvaro A., additional, Fokkens, Wytske J., additional, de Vries, Govert, additional, Gemicioglu, Bilun, additional, Giuliano, Antonio FM., additional, Linuma, Tomohisa, additional, Ivancevich, Juan Carlos, additional, Jácome, Cristina, additional, Kaidashev, Igor, additional, Kraxner, Helga, additional, Laune, Daniel, additional, Louis, Gilles, additional, Lourenço, Olga, additional, Makela, Mika, additional, Makris, Michael, additional, Morais-Almeida, Mario, additional, Mösges, Ralph, additional, Maurer, Marcus, additional, Mullol, Joaquim, additional, Nadif, Rachel, additional, Niedoszytko, Marek, additional, O’Hehir, Robyn, additional, Okamoto, Yoshitaka, additional, Ollert, Markus, additional, Olze, Heidi, additional, Patella, Vincenzo, additional, Pétré, Benoit, additional, Puggioni, Francesca, additional, Romantowski, Jan, additional, Rouadi, Philip W., additional, Reitsma, Sietze, additional, Rivero-Yeverino, Daniela, additional, Rodriguez-Gonzalez, Monica, additional, Sá-Sousa, Ana, additional, Savouré, Marine, additional, Serpa, Faradiba S., additional, Shamji, Mohamed H., additional, Sheikh, Aziz, additional, Ulrik, Charlotte Suppli, additional, Sofiev, Mikhail, additional, Sova, Milan, additional, Sperl, Annette, additional, Todo-Bom, Ana, additional, Tomazic, Peter V., additional, Toppila-Salmi, Sanna, additional, Tsiligianni, Ioanna, additional, Valovirta, Erkka, additional, van Eerd, Michiel, additional, Zidarn, Mihaela, additional, Blain, Hubert, additional, Boulet, Louis-Philippe, additional, Brusselle, Guy, additional, Buhl, Roland, additional, Charpin, Denis, additional, Casale, Thomas, additional, Chivato, Tomas, additional, Correia-de-Sousa, Jaime, additional, Corrigan, Christopher, additional, de Blay, Frédéric, additional, Del Giacco, Stefano, additional, Devillier, Philippe, additional, Dykewicz, Mark, additional, Fiocchi, Alessandro, additional, Giovannini, Mattia, additional, Jassem, Ewa, additional, Jutel, Marek, additional, Keil, Thomas, additional, La Grutta, Stefania, additional, Lipworth, Brian, additional, Papi, Alberto, additional, Pépin, Jean-Louis, additional, Quirce, Santiago, additional, Cordeiro, Carlos Robalo, additional, Torres, Maria J., additional, and Usmani, Omar S., additional

Published
2024
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7. Asthma, Eosinophils, and Interleukin-5

Author

Kay, A. Barry, primary, Hamid, Qutayba, additional, Robinson, Douglas S., additional, Bentley, Andrew M., additional, Tsicopoulos, Anne, additional, Ying, Sun, additional, Moqbel, Redwan, additional, Corrigan, Christopher J., additional, and Durham, Stephen R., additional

Published
2019
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8. Supplementary Table S1 from Anti-Folate Receptor-α IgE but not IgG Recruits Macrophages to Attack Tumors via TNFα/MCP-1 Signaling

Author

Josephs, Debra H., primary, Bax, Heather J., primary, Dodev, Tihomir, primary, Georgouli, Mirella, primary, Nakamura, Mano, primary, Pellizzari, Giulia, primary, Saul, Louise, primary, Karagiannis, Panagiotis, primary, Cheung, Anthony, primary, Herraiz, Cecilia, primary, Ilieva, Kristina M., primary, Correa, Isabel, primary, Fittall, Matthew, primary, Crescioli, Silvia, primary, Gazinska, Patrycja, primary, Woodman, Natalie, primary, Mele, Silvia, primary, Chiaruttini, Giulia, primary, Gilbert, Amy E., primary, Koers, Alexander, primary, Bracher, Marguerite, primary, Selkirk, Christopher, primary, Lentfer, Heike, primary, Barton, Claire, primary, Lever, Elliott, primary, Muirhead, Gareth, primary, Tsoka, Sophia, primary, Canevari, Silvana, primary, Figini, Mariangela, primary, Montes, Ana, primary, Downes, Noel, primary, Dombrowicz, David, primary, Corrigan, Christopher J., primary, Beavil, Andrew J., primary, Nestle, Frank O., primary, Jones, Paul S., primary, Gould, Hannah J., primary, Sanz-Moreno, Victoria, primary, Blower, Philip J., primary, Spicer, James F., primary, and Karagiannis, Sophia N., primary

Published
2023
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9. Data from Anti-Folate Receptor-α IgE but not IgG Recruits Macrophages to Attack Tumors via TNFα/MCP-1 Signaling

Author

Josephs, Debra H., primary, Bax, Heather J., primary, Dodev, Tihomir, primary, Georgouli, Mirella, primary, Nakamura, Mano, primary, Pellizzari, Giulia, primary, Saul, Louise, primary, Karagiannis, Panagiotis, primary, Cheung, Anthony, primary, Herraiz, Cecilia, primary, Ilieva, Kristina M., primary, Correa, Isabel, primary, Fittall, Matthew, primary, Crescioli, Silvia, primary, Gazinska, Patrycja, primary, Woodman, Natalie, primary, Mele, Silvia, primary, Chiaruttini, Giulia, primary, Gilbert, Amy E., primary, Koers, Alexander, primary, Bracher, Marguerite, primary, Selkirk, Christopher, primary, Lentfer, Heike, primary, Barton, Claire, primary, Lever, Elliott, primary, Muirhead, Gareth, primary, Tsoka, Sophia, primary, Canevari, Silvana, primary, Figini, Mariangela, primary, Montes, Ana, primary, Downes, Noel, primary, Dombrowicz, David, primary, Corrigan, Christopher J., primary, Beavil, Andrew J., primary, Nestle, Frank O., primary, Jones, Paul S., primary, Gould, Hannah J., primary, Sanz-Moreno, Victoria, primary, Blower, Philip J., primary, Spicer, James F., primary, and Karagiannis, Sophia N., primary

Published
2023
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10. Supplementary Materials and Methods from Anti-Folate Receptor-α IgE but not IgG Recruits Macrophages to Attack Tumors via TNFα/MCP-1 Signaling

Author

Josephs, Debra H., primary, Bax, Heather J., primary, Dodev, Tihomir, primary, Georgouli, Mirella, primary, Nakamura, Mano, primary, Pellizzari, Giulia, primary, Saul, Louise, primary, Karagiannis, Panagiotis, primary, Cheung, Anthony, primary, Herraiz, Cecilia, primary, Ilieva, Kristina M., primary, Correa, Isabel, primary, Fittall, Matthew, primary, Crescioli, Silvia, primary, Gazinska, Patrycja, primary, Woodman, Natalie, primary, Mele, Silvia, primary, Chiaruttini, Giulia, primary, Gilbert, Amy E., primary, Koers, Alexander, primary, Bracher, Marguerite, primary, Selkirk, Christopher, primary, Lentfer, Heike, primary, Barton, Claire, primary, Lever, Elliott, primary, Muirhead, Gareth, primary, Tsoka, Sophia, primary, Canevari, Silvana, primary, Figini, Mariangela, primary, Montes, Ana, primary, Downes, Noel, primary, Dombrowicz, David, primary, Corrigan, Christopher J., primary, Beavil, Andrew J., primary, Nestle, Frank O., primary, Jones, Paul S., primary, Gould, Hannah J., primary, Sanz-Moreno, Victoria, primary, Blower, Philip J., primary, Spicer, James F., primary, and Karagiannis, Sophia N., primary

Published
2023
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11. Supplementary Figure Legends from Anti-Folate Receptor-α IgE but not IgG Recruits Macrophages to Attack Tumors via TNFα/MCP-1 Signaling

Author

Josephs, Debra H., primary, Bax, Heather J., primary, Dodev, Tihomir, primary, Georgouli, Mirella, primary, Nakamura, Mano, primary, Pellizzari, Giulia, primary, Saul, Louise, primary, Karagiannis, Panagiotis, primary, Cheung, Anthony, primary, Herraiz, Cecilia, primary, Ilieva, Kristina M., primary, Correa, Isabel, primary, Fittall, Matthew, primary, Crescioli, Silvia, primary, Gazinska, Patrycja, primary, Woodman, Natalie, primary, Mele, Silvia, primary, Chiaruttini, Giulia, primary, Gilbert, Amy E., primary, Koers, Alexander, primary, Bracher, Marguerite, primary, Selkirk, Christopher, primary, Lentfer, Heike, primary, Barton, Claire, primary, Lever, Elliott, primary, Muirhead, Gareth, primary, Tsoka, Sophia, primary, Canevari, Silvana, primary, Figini, Mariangela, primary, Montes, Ana, primary, Downes, Noel, primary, Dombrowicz, David, primary, Corrigan, Christopher J., primary, Beavil, Andrew J., primary, Nestle, Frank O., primary, Jones, Paul S., primary, Gould, Hannah J., primary, Sanz-Moreno, Victoria, primary, Blower, Philip J., primary, Spicer, James F., primary, and Karagiannis, Sophia N., primary

Published
2023
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12. Supplementary Figure S1 from Anti-Folate Receptor-α IgE but not IgG Recruits Macrophages to Attack Tumors via TNFα/MCP-1 Signaling

Author

Josephs, Debra H., primary, Bax, Heather J., primary, Dodev, Tihomir, primary, Georgouli, Mirella, primary, Nakamura, Mano, primary, Pellizzari, Giulia, primary, Saul, Louise, primary, Karagiannis, Panagiotis, primary, Cheung, Anthony, primary, Herraiz, Cecilia, primary, Ilieva, Kristina M., primary, Correa, Isabel, primary, Fittall, Matthew, primary, Crescioli, Silvia, primary, Gazinska, Patrycja, primary, Woodman, Natalie, primary, Mele, Silvia, primary, Chiaruttini, Giulia, primary, Gilbert, Amy E., primary, Koers, Alexander, primary, Bracher, Marguerite, primary, Selkirk, Christopher, primary, Lentfer, Heike, primary, Barton, Claire, primary, Lever, Elliott, primary, Muirhead, Gareth, primary, Tsoka, Sophia, primary, Canevari, Silvana, primary, Figini, Mariangela, primary, Montes, Ana, primary, Downes, Noel, primary, Dombrowicz, David, primary, Corrigan, Christopher J., primary, Beavil, Andrew J., primary, Nestle, Frank O., primary, Jones, Paul S., primary, Gould, Hannah J., primary, Sanz-Moreno, Victoria, primary, Blower, Philip J., primary, Spicer, James F., primary, and Karagiannis, Sophia N., primary

Published
2023
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19. T Cells in Allergic Disease

Author

Hawrylowicz, Catherine M., Corrigan, Christopher, Faith, Alex, Pawankar, Ruby, editor, Holgate, Stephen T., editor, and Rosenwasser, Lanny J., editor

Published
2009
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21. Allergy

Author

Alam, Saima, primary and Corrigan, Christopher, additional

Published
2017
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28. Diminished Sarco/Endoplasmic Reticulum Ca²⁺ ATPase (SERCA) Expression Contributes to Airway Remodelling in Bronchial Asthma

Author

Mahn, Katharina, Hirst, Stuart J., Ying, Sun, Holt, Mark R., Lavender, Paul, Ojo, Oluwaseun O., Siew, Leonard, Simcock, David E., McVicker, Clare G., Kanabar, Varsha, Snetkov, Vladimir A., O'Connor, Brian J., Karner, Charlotta, Cousins, David J., Macedo, Patricia, Chung, K. Fan, Corrigan, Christopher J., Ward, Jeremy P. T., Lee, Tak H., and Austen, K. Frank

Published
2009
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31. Transcriptome profiling reveals a potential role for antagonism of the calcium-sensing receptor in the prophylaxis of idiopathic pulmonary fibrosis

Author

Wolffs, Kasope L., primary, Pass, Daniel A., additional, Mansfield, Beth, additional, Bruce, Richard T., additional, Popov, Petar A., additional, Corrigan, Christopher J., additional, Ward, Jeremy P.T., additional, Kemp, Paul J., additional, Hope-Gill, Benjamin, additional, and Riccardi, Daniela, additional

Published
2021
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32. Double-blind randomised placebo-controlled trial of bolus-dose vitamin D3 supplementation in adults with asthma (ViDiAs)

Author

Martineau, Adrian R, MacLaughlin, Beverley D, Hooper, Richard L, Barnes, Neil C, Jolliffe, David A, Greiller, Claire L, Kilpin, Kate, McLaughlin, David, Fletcher, Gareth, Mein, Charles A, Hoti, Mimoza, Walton, Robert, Grigg, Jonathan, Timms, Peter M, Rajakulasingam, Raj K, Bhowmik, Angshu, Rowe, Marion, Venton, Timothy R, Choudhury, Aklak B, Simcock, David E, Sadique, Zia, Monteiro, William R, Corrigan, Christopher J, Hawrylowicz, Catherine M, and Griffiths, Christopher J

Published
2015
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34. Ligation of TLR9 induced on human IL-10-secreting Tregs by 1[alpha],25-dihydroxyvitamin D3 abrogates regulatory function

Author

Urry, Zoe, Xystrakis, Emmanuel, Richards, David F., McDonald, Joanne, Sattar, Zahid, Cousins, David J., Corrigan, Christopher J., Hickman, Emma, Brown, Zarin, and Hawrylowicz, Catherine M.

Subjects
Cellular signal transduction -- Research, Interleukin-10 -- Health aspects, Interleukin-10 -- Research, Cell receptors -- Research, Cell receptors -- Genetic aspects, Cell receptors -- Physiological aspects, Cancer -- Research, Oncology, Experimental
Abstract

Signaling through the TLR family of molecular pattern recognition receptors has been implicated in the induction of innate and adaptive immune responses. A role for TLR signaling in the maintenance and/or regulation of Treg function has been proposed, however its functional relevance remains unclear. Here we have shown that TLR9 is highly expressed by human Treg secreting the antiinflammatory cytokine IL-10 induced following stimulation of blood and tissue [CD3.sup.+] T cells in the presence of 1[alpha],25-dihydroxyvitamin D3 (1[alpha]25VitD3), the active form of Vitamin D, with or without the glucocorticoid dexamethasone. By contrast, TLR9 was not highly expressed by naturally occurring [CD4.sup.+][CD25.sup.+] Treg or by Th1 and Th2 effector cells. Induction of TLR9, but not other TLRs, was IL-10 dependent and primarily regulated by 1[alpha]25VitD3 in vitro. Furthermore, ingestion of calcitriol (1[alpha]25VitD3) by human volunteers led to an increase of both IL-10 and TLR9 expression by [CD3.sup.+][CD4.sup.+] T cells analyzed directly ex vivo. Stimulation of 1[alpha]25VitD3-induced IL-10-secreting Treg with TLR9 agonists, CpG oligonucleotides, resulted in decreased IL-10 and IFN-[gamma] synthesis and a concurrent loss of regulatory function, but, unexpectedly, increased IL-4 synthesis. We therefore suggest that TLR9 could be used to monitor and potentially modulate the function of 1[alpha]25VitD3-induced IL-10-secreting Treg in vivo, and that this has implications in cancer therapy and vaccine design., Introduction The TLRs represent a family of evolutionarily conserved receptors, which recognize pathogen-associated molecular patterns (PAMPs) and certain host molecules. Ten TLRs (TLR1-10) have been identified in humans to date. [...]

Published
2009

36. Inhaled Corticosteroids Prescribed for COPD Patients with Mild or Moderate Airflow Limitation: Who Warrants a Trial of Withdrawal?

Author

Harries, Timothy H, Gilworth, Gill, Corrigan, Christopher J, Murphy, Patrick B, Hart, Nicholas, Thomas, Mike, and White, Patrick T

Subjects
chronic obstructive, Short Report, mild airflow limitation, Beclomethasone, International Journal of Chronic Obstructive Pulmonary Disease, Severity of Illness Index, respiratory tract diseases, Airway Obstruction, Pulmonary Disease, Chronic Obstructive, Withholding Treatment, drug withdrawal, Administration, Inhalation, Humans, moderate airflow limitation, inhaled corticosteroids, Glucocorticoids, pulmonary disease
Abstract

Timothy H Harries,1 Gill Gilworth,1 Christopher J Corrigan,2 Patrick B Murphy,3 Nicholas Hart,3 Mike Thomas,4 Patrick T White1 1Department of Public Health and Primary Care, School of Population Health and Environmental Sciences, King’s College London, London, UK; 2Department of Asthma Allergy and Respiratory Science, King’s College London, London, UK; 3Lane Fox Respiratory Unit, Guy’s and St. Thomas’ NHS Foundation Trust and King’s College London, London, UK; 4Primary Care and Population Medicine, University of Southampton, Southampton, UKCorrespondence: Timothy H HarriesDepartment of Public Health and Primary Care, School of Population Health and Environmental Sciences, King’s College London 3rd Floor Addison House, Guys Campus, London SE1 1UL, UKTel +44 20 7836 5454Email timothy.harries@kcl.ac.ukAbstract: COPD patients prescribed inhaled corticosteroids (ICS) outside guidelines should be targeted for ICS withdrawal. Within a primary care population of 209,618 we used a combination of digital search algorithm, individual record review, and clinical review to identify COPD patients suitable for a trial of ICS withdrawal. At most, 39% of COPD patients with mild or moderate airflow limitation prescribed ICS were suitable for withdrawal according to Global Initiative for Chronic Obstructive Lung Disease (GOLD) guidelines. Recurrent exacerbations and reversible airway obstruction were the main reasons for patients’ unsuitability for withdrawal. Identifying COPD patients in whom ICS withdrawal should be considered presents a challenge to primary care clinicians.Keywords: pulmonary disease, chronic obstructive, inhaled corticosteroids, drug withdrawal, mild airflow limitation, moderate airflow limitation

Published
2020

37. Inhaled Corticosteroids Prescribed for COPD Patients with Mild or Moderate Airflow Limitation: Who Warrants a Trial of Withdrawal?

Author

Harries,Timothy H, Gilworth,Gill, Corrigan,Christopher J, Murphy,Patrick B, Hart,Nicholas, Thomas,Mike, White,Patrick T, Harries,Timothy H, Gilworth,Gill, Corrigan,Christopher J, Murphy,Patrick B, Hart,Nicholas, Thomas,Mike, and White,Patrick T

Abstract

Timothy H Harries,1 Gill Gilworth,1 Christopher J Corrigan,2 Patrick B Murphy,3 Nicholas Hart,3 Mike Thomas,4 Patrick T White1 1Department of Public Health and Primary Care, School of Population Health and Environmental Sciences, King’s College London, London, UK; 2Department of Asthma Allergy and Respiratory Science, King’s College London, London, UK; 3Lane Fox Respiratory Unit, Guy’s and St. Thomas’ NHS Foundation Trust and King’s College London, London, UK; 4Primary Care and Population Medicine, University of Southampton, Southampton, UKCorrespondence: Timothy H HarriesDepartment of Public Health and Primary Care, School of Population Health and Environmental Sciences, King’s College London 3rd Floor Addison House, Guys Campus, London SE1 1UL, UKTel +44 20 7836 5454Email timothy.harries@kcl.ac.ukAbstract: COPD patients prescribed inhaled corticosteroids (ICS) outside guidelines should be targeted for ICS withdrawal. Within a primary care population of 209,618 we used a combination of digital search algorithm, individual record review, and clinical review to identify COPD patients suitable for a trial of ICS withdrawal. At most, 39% of COPD patients with mild or moderate airflow limitation prescribed ICS were suitable for withdrawal according to Global Initiative for Chronic Obstructive Lung Disease (GOLD) guidelines. Recurrent exacerbations and reversible airway obstruction were the main reasons for patients’ unsuitability for withdrawal. Identifying COPD patients in whom ICS withdrawal should be considered presents a challenge to primary care clinicians.Keywords: pulmonary disease, chronic obstructive, inhaled corticosteroids, drug withdrawal, mild airflow limitation, moderate airflow limitation

Published
2020

42. Leukotriene-receptor expression on nasal mucosal inflammatory cells in aspirin-sensitive rhinosinusitis

Author

Sousa, Ana R., parikh, Abhi, Scadding, Glenis, Corrigan, Christopher J., and Lee, Tak H.

Subjects
Leukotrienes -- Health aspects, Aspirin -- Adverse and side effects, Asthma -- Physiological aspects
Abstract

Increased blood levels of leukotrienes may cause aspirin sensitivity in people with asthma and chronic sinusitis, according to a study of 34 people. Leukotrienes are inflammatory substances produced by some cells, including mast cells and eosinophils.

Published
2002

48. Characterization of Negative Allosteric Modulators of the Calcium-Sensing Receptor for Repurposing as a Treatment of Asthma

Author

Yarova, Polina L., primary, Huang, Ping, additional, Schepelmann, Martin W., additional, Bruce, Richard, additional, Ecker, Rupert, additional, Nica, Robert, additional, Telezhkin, Vsevolod, additional, Traini, Daniela, additional, Gomes dos Reis, Larissa, additional, Kidd, Emma J., additional, Ford, William R., additional, Broadley, Kenneth J., additional, Kariuki, Benson M., additional, Corrigan, Christopher J., additional, Ward, Jeremy P.T., additional, Kemp, Paul J., additional, and Riccardi, Daniela, additional

Published
2020
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49. Abstract CT141: Phase 1 trial of MOv18, a first-in-class IgE antibody therapy for cancer

Author

Spicer, James, primary, Basu, Bristi, additional, Montes, Ana, additional, Banerji, Udai, additional, Kristeleit, Rebecca, additional, Veal, Gareth J., additional, Corrigan, Christopher, additional, Till, Stephen, additional, Nintos, George, additional, Brier, Timothy, additional, Funingana, Ionut G., additional, Ang, Joo Ern, additional, Zaki, Kam, additional, Griffin, Annie, additional, Barton, Claire, additional, Jones, Paul, additional, Mellor, Sarah, additional, Brook, Susan, additional, Stoddart, Katie, additional, Selkirk, Christopher, additional, Carroll, Simon, additional, Lentfer, Heike, additional, Woodman, Natalie, additional, Pope, Amy, additional, Pellizzari, Giulia, additional, Nakamura, Mano, additional, Ilieva, Kristina M., additional, Khiabany, Atousa, additional, Stavraka, Chara, additional, Gould, Hannah, additional, Chauhan, Jitesh, additional, Bax, Heather, additional, Pinder, Sarah, additional, Josephs, Debra, additional, and Karagiannis, Sophia, additional

Published
2020
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50. Basophils from Cancer Patients Respond to Immune Stimuli and Predict Clinical Outcome

Author

Bax, Heather J., primary, Chauhan, Jitesh, additional, Stavraka, Chara, additional, Khiabany, Atousa, additional, Nakamura, Mano, additional, Pellizzari, Giulia, additional, Ilieva, Kristina M., additional, Lombardi, Sara, additional, Gould, Hannah J., additional, Corrigan, Christopher J., additional, Till, Stephen J., additional, Katugampola, Sidath, additional, Jones, Paul S., additional, Barton, Claire, additional, Winship, Anna, additional, Ghosh, Sharmistha, additional, Montes, Ana, additional, Josephs, Debra H., additional, Spicer, James F., additional, and Karagiannis, Sophia N., additional

Published
2020
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