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1. Guinea worm disease: A neglected diseases on the verge of eradication

Author

Pellegrino, Carmen, Patti, Giulia, Camporeale, Michele, Belati, Alessandra, Novara, Roberta, Papagni, Roberta, Frallonardo, Luisa, Diella, Lucia, Guido, Giacomo, De Vita, Elda, Totaro, Valentina, Segala, Francesco Vladimiro, Veronese, Nicola, Cotugno, Sergio, Bavaro, Davide Fiore, Putoto, Giovanni, Bevilacqua, Nazario, Castellani, Chiara, Nicastri, Emanuele, Saracino, Annalisa, and Gennaro, Francesco Di

Published
2022

2. Incidence and burden of long COVID in Africa: a systematic review and meta-analysis

Author

Frallonardo, Luisa, Segala, Francesco Vladimiro, Chhaganlal, Kajal D., Yelshazly, Mohmaoud, Novara, Roberta, Cotugno, Sergio, Guido, Giacomo, Papagni, Roberta, Colpani, Agnese, De Vito, Andrea, Barbagallo, Mario, Madeddu, Giordano, Babudieri, Sergio, Lochoro, Peter, Ictho, Jerry, Putoto, Giovanni, Veronese, Nicola, Saracino, Annalisa, and Di Gennaro, Francesco

Published
2023
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4. Cardiac Tuberculosis: A Case Series from Ethiopia, Italy, and Uganda and a Literature Review

Author

Cotugno, Sergio, primary, Guido, Giacomo, additional, Manco Cesari, Giorgia, additional, Ictho, Jerry, additional, Lochoro, Peter, additional, Amone, James, additional, Segala, Francesco Vladimiro, additional, De Vita, Elda, additional, Lattanzio, Rossana, additional, Okori, Samuel, additional, De Iaco, Giuseppina, additional, Girma, Adisu, additional, Sura, Abata, additional, Hessebo, Eriballo Tariku, additional, Balsemin, Franco, additional, Putoto, Giovanni, additional, Ronga, Luigi, additional, Manenti, Fabio, additional, Facci, Enzo, additional, Saracino, Annalisa, additional, and Di Gennaro, Francesco, additional

Published
2024
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5. Active close contact investigation of tuberculosis through computer-aided detection and stool Xpert MTB/RIF among people living in Oromia Region, Ethiopia (CADOOL Study): protocol for a prospective, cross-sectional study

Author

Segala, Francesco Vladimiro, primary, Nigussa, Worku, additional, Guido, Giacomo, additional, Kenate, Birhanu, additional, Facci, Enzo, additional, Tsegaye, Ademe, additional, Gulo, Berhanu, additional, Manenti, Fabio, additional, Bobosha, Kidist, additional, Cotugno, Sergio, additional, Asmare, Azmach Biset, additional, Cavallin, Francesco, additional, Tilahun, Melaku, additional, Miccio, Maddalena, additional, Abdissa, Alemseged, additional, Putoto, Giovanni, additional, Saracino, Annalisa, additional, and Di Gennaro, Francesco, additional

Published
2023
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6. Knowledge, attitudes, and practices about HIV and other sexually transmitted infections among High School students in Southern Italy: A cross-sectional survey.

Author

Di Gennaro, Francesco, Segala, Francesco Vladimiro, Guido, Giacomo, Poliseno, Mariacristina, De Santis, Laura, Belati, Alessandra, Santoro, Carmen Rita, Bottalico, Irene Francesca, Pellegrino, Carmen, Novara, Roberta, Frallonardo, Luisa, Cormio, Mariangela, Camporeale, Michele, Cotugno, Sergio, Giliberti, Vincenzo, Di Gregorio, Stefano, Totaro, Valentina, Catucci, Nicola, De Giosa, Anna, and Giusto, Roberta

Subjects
SEXUALLY transmitted diseases, HIGH school students, HUMAN papillomavirus, HIV, INFORMATION-seeking behavior, CONSTRUCTION cost estimates
Abstract

High School students, recognized as a high-risk group for sexually transmitted infections (STIs), were the focal point of an educational campaign in Southern Italy to share information and good practices about STIs and HIV/AIDS. A baseline survey comprising 76 items was conducted via the REDCap platform to assess students' initial knowledge, attitudes, and practices (KAP) related to STIs and HIV/AIDS. Sociodemographic variables were also investigated. The association between variables and KAP score was assessed by Kruskal-Wallis' or Spearman's test, as appropriate. An ordinal regression model was built to estimate the effect size, reported as odds ratio (OR) with a 95% confidence interval (CI), for achieving higher KAP scores among students features. On a scale of 0 to 29, 1702 participants achieved a median KAP score of 14 points. Higher scores were predominantly reported by students from classical High Schools (OR 3.19, 95% C.I. 1.60–6.33, p<0.001). Additionally, elevated scores were associated with sexually active students (OR 1.48, 95% C.I. 1.12–1.96, p = 0.01), those vaccinated against Human Papilloma Virus (OR 2.47, 95% C.I. 1.89–3.24, p<0.001), those who had used emergency contraception (OR 1.56, 95% C.I. 1.09–2.24, p = 0.02, Table 2) and those obtaining information from TikTok (OR 1.62, 95% C.I. 1.14–2.30, p = 0.01). Conversely, being heterosexual was associated with an overall lower score (OR 0.48, 95% C.I. 0.32–0.73, p<0.001). High School students, often due to early sexual debut, seek information about HIV and STIs independently using social channels. However, the overall level of knowledge, attitudes, and practices remains low. Urgent school-based interventions are needed for this age group. [ABSTRACT FROM AUTHOR]

Published
2024
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7. Stool Xpert MTB/RIF as a possible diagnostic alternative to sputum in Africa: a systematic review and meta-analysis

Author

Segala, Francesco Vladimiro, primary, Papagni, Roberta, additional, Cotugno, Sergio, additional, De Vita, Elda, additional, Susini, Maria Chiara, additional, Filippi, Valeria, additional, Tulone, Ottavia, additional, Facci, Enzo, additional, Lattanzio, Rossana, additional, Marotta, Claudia, additional, Manenti, Fabio, additional, Bavaro, Davide Fiore, additional, De Iaco, Giuseppina, additional, Putoto, Giovanni, additional, Veronese, Nicola, additional, Barbagallo, Mario, additional, Saracino, Annalisa, additional, and Di Gennaro, Francesco, additional

Published
2023
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8. Human African Trypanosomiasis (sleeping sickness): Current knowledge and future challenges

Author

Papagni, Roberta, primary, Novara, Roberta, additional, Minardi, Maria Letizia, additional, Frallonardo, Luisa, additional, Panico, Gianfranco Giorgio, additional, Pallara, Elisabetta, additional, Cotugno, Sergio, additional, Ascoli Bartoli, Tommaso, additional, Guido, Giacomo, additional, De Vita, Elda, additional, Ricciardi, Aurelia, additional, Totaro, Valentina, additional, Camporeale, Michele, additional, Segala, Francesco Vladimiro, additional, Bavaro, Davide Fiore, additional, Patti, Giulia, additional, Brindicci, Gaetano, additional, Pellegrino, Carmen, additional, Mariani, Michele Fabio, additional, Putoto, Giovanni, additional, Sarmati, Loredana, additional, Castellani, Chiara, additional, Saracino, Annalisa, additional, Di Gennaro, Francesco, additional, and Nicastri, Emanuele, additional

Published
2023
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9. Intravenous Fosfomycin as Adjunctive Therapy for Gram-Negative Bacteria Bloodstream Infections: A Propensity Score Adjusted Retrospective Cohort Study

Author

Belati, Alessandra, Diella, Lucia, Bavaro, Davide Fiore, De Santis, Laura, Cotugno, Sergio, De Gennaro, Nicolò, Brindicci, Gaetano, Maggiore, Maria Elena, Indraccolo, Francesca, Di Gennaro, Francesco, Ronga, Luigi, Mosca, Adriana, Stufano, Monica, Dalfino, Lidia, Grasso, Salvatore, and Saracino, Annalisa

Published
2024
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10. Knowledge, Attitudes and Practices on Cholera and Water, Sanitation, and Hygiene among Internally Displaced Persons in Cabo Delgado Province, Mozambique

Author

Di Gennaro, Francesco, primary, Occa, Edoardo, additional, Chitnis, Ketan, additional, Guelfi, Giorgia, additional, Canini, Andrea, additional, Chuau, Inusso, additional, Cadorin, Simone, additional, Bavaro, Davide F., additional, Ramirez, Lucy, additional, Marotta, Claudia, additional, Cotugno, Sergio, additional, Segala, Francesco V., additional, Ghelardi, Angelo, additional, Saracino, Annalisa, additional, Periquito, Isabel M., additional, Putoto, Giovanni, additional, and Mussa, Ally, additional

Published
2023
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11. High risk of unsuccessful treatment outcome in migrant population with tuberculosis: Data from three Italian hospitals

Author

Di Gennaro, Francesco, primary, Cotugno, Sergio, additional, Fasano, Massimo, additional, Ricciardi, Aurelia, additional, Ronga, Luigi, additional, Lattanzio, Rossana, additional, Grimaldi, Anna, additional, Bavaro, Davide Fiore, additional, Ciarallo, Marianna, additional, Garzone, Stefania, additional, De Iaco, Giuseppina, additional, Guido, Giacomo, additional, Fiore, Josè Ramon, additional, Brindicci, Gaetano, additional, Santoro, Carmen Rita, additional, Sica, Salvatore, additional, Iacovazzi, Tiziana Loredana, additional, Santantonio, Teresa Antonia, additional, and Saracino, Annalisa, additional

Published
2023
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12. Onchocerciasis: Current knowledge and future goals

Author

Frallonardo, Luisa, primary, Di Gennaro, Francesco, additional, Panico, Gianfranco Giorgio, additional, Novara, Roberta, additional, Pallara, Elisabetta, additional, Cotugno, Sergio, additional, Guido, Giacomo, additional, De Vita, Elda, additional, Ricciardi, Aurelia, additional, Totaro, Valentina, additional, Camporeale, Michele, additional, De Iaco, Giuseppina, additional, Bavaro, Davide Fiore, additional, Lattanzio, Rossana, additional, Patti, Giulia, additional, Brindicci, Gaetano, additional, Papagni, Roberta, additional, Pellegrino, Carmen, additional, Santoro, Carmen Rita, additional, Segala, Francesco Vladimiro, additional, Putoto, Giovanni, additional, Nicastri, Emanuele, additional, and Saracino, Annalisa, additional

Published
2022
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13. Loa loa in the Vitreous Cavity of the Eye: A Case Report and State of Art

Author

Pallara, Elisabetta, primary, Cotugno, Sergio, additional, Guido, Giacomo, additional, De Vita, Elda, additional, Ricciardi, Aurelia, additional, Totaro, Valentina, additional, Camporeale, Michele, additional, Frallonardo, Luisa, additional, Novara, Roberta, additional, Panico, Gianfranco G., additional, Puzo, Pasquale, additional, Alessio, Giovanni, additional, Sablone, Sara, additional, Mariani, Michele, additional, De Iaco, Giuseppina, additional, Milano, Eugenio, additional, Bavaro, Davide F., additional, Lattanzio, Rossana, additional, Patti, Giulia, additional, Papagni, Roberta, additional, Pellegrino, Carmen, additional, Saracino, Annalisa, additional, and Di Gennaro, Francesco, additional

Published
2022
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14. Interventions for Improving Long COVID-19 Symptomatology: A Systematic Review

Author

Veronese, Nicola, primary, Bonica, Roberta, additional, Cotugno, Sergio, additional, Tulone, Ottavia, additional, Camporeale, Michele, additional, Smith, Lee, additional, Trott, Mike, additional, Bruyere, Olivier, additional, Mirarchi, Luigi, additional, Rizzo, Giuseppina, additional, Bavaro, Davide Fiore, additional, Barbagallo, Mario, additional, Dominguez, Ligia J., additional, Marotta, Claudia, additional, Silenzi, Andrea, additional, Nicastri, Emanuele, additional, Saracino, Annalisa, additional, and Di Gennaro, Francesco, additional

Published
2022
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15. Interventions For Improving Long Covid Symptomatology: A Systematic Review

Author

Veronese, Nicola, Bonica, Roberta, Cotugno, Sergio, Tulone, Ottavia, Camporeale, Michele, Smith, Lee, Trott, Mike, Bruyere, Olivier, Mirarchi, Luigi, Rizzo, Giuseppina, Fiore Bavaro, Davide, Barbagallo, Mario, Dominguez, Ligia, Marotta, Claudia, Silenzi, Andrea, Nicastri, Emanuele, Saracino, Annalisa, and Di Gennaro, Francesco

Abstract

Introduction: Although the understanding of several aspects of long COVID-19 syndrome is increasing, there is limited literature regarding the treatment of these signs and symptoms. The aim of our systematic review was to understand which therapies have proved effective against the symptoms of long COVID-19. Methods: A systematic search for randomized controlled or clinical trials in several databases was conducted through 15 May 2022. Specific inclusion criteria included: (1) intervention studies, either randomized controlled (RCTs) or clinical trials; (2) diagnosis of long COVID-19, according to the World Health Organization criteria; (3) presence of long COVID-19 for at least 12 weeks after SARS-CoV-2 infection. Results: We initially found 1638 articles to screen. After removing 1602 works based on their title/abstract, we considered 35 full texts, and among them, two intervention studies were finally included. The first RCT focused on the greater improvement of treatment combining olfactory rehabilitation with oral supplementation with Palmitoylethanolamide and Luteolin in patients with olfactory dysfunction after COVID-19. The second study evaluated the positive impact of aromatherapy vs. standard care in adult females affected by fatigue. Conclusion: Our systematic review found only two intervention studies focused on patients affected by long COVID-19. More intervention studies are needed to investigate potentially positive interventions for long COVID-19 symptoms.

Published
2022

16. Impact of Vitamin D in Prophylaxis and Treatment in Tuberculosis Patients

Author

Papagni, Roberta, primary, Pellegrino, Carmen, additional, Di Gennaro, Francesco, additional, Patti, Giulia, additional, Ricciardi, Aurelia, additional, Novara, Roberta, additional, Cotugno, Sergio, additional, Musso, Maria, additional, Guido, Giacomo, additional, Ronga, Luigi, additional, Stolfa, Stefania, additional, Bavaro, Davide Fiore, additional, Romanelli, Federica, additional, Totaro, Valentina, additional, Lattanzio, Rossana, additional, De Iaco, Giuseppina, additional, Palmieri, Fabrizio, additional, Saracino, Annalisa, additional, and Gualano, Gina, additional

Published
2022
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17. Predictors for Pulmonary Tuberculosis Outcome and Adverse Events in an Italian Referral Hospital: A Nine-Year Retrospective Study (2013–2021)

Author

Di Gennaro, Francesco, primary, Lattanzio, Rossana, additional, Guido, Giacomo, additional, Ricciardi, Aurelia, additional, Novara, Roberta, additional, Patti, Giulia, additional, Cotugno, Sergio, additional, De Vita, Elda, additional, Brindicci, Gaetano, additional, Mariano, Michele Fabiano, additional, Ronga, Luigi, additional, Santoro, Carmen Rita, additional, Romanelli, Federica, additional, Stolfa, Stefania, additional, Papagni, Roberta, additional, Bavaro, Davide Fiore, additional, De Iaco, Giusi, additional, and Saracino, Annalisa, additional

Published
2022
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18. Malaria, HIV and Malnutrition among Internally Displaced People in Mozambique During COVID-19 Pandemic: Results from a Community-Based Intervention

Author

Di Gennaro, Francesco, primary, Occa, Edocardo, additional, Ramirez, Lucy, additional, Marotta, Claudia, additional, Segala, Francesco Vladimiro, additional, Santana, Jaime, additional, Cotugno, Sergio, additional, Papagni, Roberta, additional, De Meneghi, Giovanna, additional, De Vivo, Emanuela, additional, Braque, Cati, additional, Guelfi, Giorgia, additional, Manhica, Samo, additional, Di Nunzio, Ilaria, additional, Foquisso, Nelson, additional, Opocher, Giacomo, additional, Tognon, Francesca, additional, Saracino, Annalisa, additional, and Putoto, Giovanni, additional

Published
2022
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19. Potential Role of Vitamins A, B, C, D and E in TB Treatment and Prevention: A Narrative Review

Author

Patti, Giulia, primary, Pellegrino, Carmen, additional, Ricciardi, Aurelia, additional, Novara, Roberta, additional, Cotugno, Sergio, additional, Papagni, Roberta, additional, Guido, Giacomo, additional, Totaro, Valentina, additional, De Iaco, Giuseppina, additional, Romanelli, Federica, additional, Stolfa, Stefania, additional, Minardi, Maria Letizia, additional, Ronga, Luigi, additional, Fato, Ilenia, additional, Lattanzio, Rossana, additional, Bavaro, Davide Fiore, additional, Gualano, Gina, additional, Sarmati, Loredana, additional, Saracino, Annalisa, additional, Palmieri, Fabrizio, additional, and Di Gennaro, Francesco, additional

Published
2021
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21. Guinea Worm Disease: A Neglected Diseases on the Verge of Eradication

Author

Carmen Pellegrino, Giulia Patti, Michele Camporeale, Alessandra Belati, Roberta Novara, Roberta Papagni, Luisa Frallonardo, Lucia Diella, Giacomo Guido, Elda De Vita, Valentina Totaro, Francesco Vladimiro Segala, Nicola Veronese, Sergio Cotugno, Davide Fiore Bavaro, Giovanni Putoto, Nazario Bevilacqua, Chiara Castellani, Emanuele Nicastri, Annalisa Saracino, Francesco Di Gennaro, Pellegrino, Carmen, Patti, Giulia, Camporeale, Michele, Belati, Alessandra, Novara, Roberta, Papagni, Roberta, Frallonardo, Luisa, Diella, Lucia, Guido, Giacomo, De Vita, Elda, Totaro, Valentina, Segala, Francesco Vladimiro, Veronese, Nicola, Cotugno, Sergio, Bavaro, Davide Fiore, Putoto, Giovanni, Bevilacqua, Nazario, Castellani, Chiara, Nicastri, Emanuele, Saracino, Annalisa, and Di Gennaro, Francesco

Subjects
Infectious Diseases, General Immunology and Microbiology, Public Health, Environmental and Occupational Health, Africa, Guinea worm disease, NTDs, Spirurida, dracunculiasis, neglected diseases
Abstract

Background: Dracunculiasis, also known as Guinea worm disease (GWD), is a neglected tropical disease (NTD) caused by a parasite (Dracunculus medinensis). In the past, dracunculiasis was known as “the disease of the empty granary” because of the difficulties patients had in going to work in fields or to school when affected by this disease. In tropical areas, the condition has been widespread in economically disadvantaged communities, and has been associated with reduced economic status and low levels of education. Methods: we searched PubMed, Scopus, Google Scholar, EMBASE, Cochrane Library, and WHO websites for literature addressing dracunculiasis published in the last 50 years. Results: by development and optimization of multi-layered control measures, transmission by the vector has been interrupted, but there are foci in several African countries with a high risk of compromising the results obtained in the control of this neglected disease. Conclusion: this review features state-of-the-art data on the infection prevalence, geographical distribution, diagnostics, parasite–host interactions, and the pathology of dracunculiasis. Also described are the current state and future perspectives for vector control and elimination strategies.

Published
2022

22. Knowledge, Attitudes and Practices on Cholera and Water, Sanitation, and Hygiene among Internally Displaced Persons in Cabo Delgado Province, Mozambique.

Author

Di Gennaro F, Occa E, Chitnis K, Guelfi G, Canini A, Chuau I, Cadorin S, Bavaro DF, Ramirez L, Marotta C, Cotugno S, Segala FV, Ghelardi A, Saracino A, Periquito IM, Putoto G, and Mussa A

Subjects
Child, Humans, Female, Child, Preschool, Adult, Male, Sanitation, Water, Mozambique epidemiology, Cross-Sectional Studies, Health Knowledge, Attitudes, Practice, Hygiene, Refugees, Cholera epidemiology, Cholera prevention & control
Abstract

In disaster situations, cholera outbreaks represent a public health emergency due to their high fatality rates and high spreading risk through camps for refugees and internally displaced persons (IDPs). The aim of this study is to examine water, sanitation, and hygiene attitudes and cholera knowledge, attitude, and practice (KAP) among people living in resettlement sites in Cabo Delgado, the northernmost province of Mozambique. Between January 1 and March 31, 2022, a cross-sectional survey was conducted by administering a face-to-face interview to IDPs and residents in six relocation sites in Cabo Delgado Province. A total of 440 people were enrolled in the study. Overall, 77.8% (N = 342) were female, 61% (N = 268) were younger than 35 years old, and 60.5% (N = 266) reported primary school to be the highest education level. Seventy-five percent (N = 334) of participants lived with children under 5 years old. Thirty-one percent (N = 140) and 11.8% (N = 52) of the respondents reported, respectively, at least one cholera case and at least one diarrheal-related death among their family members in the previous 2 years. In multivariate analysis, being female, being younger than 35 years old, having attained a higher education level, owning a phone, or having soap at home were factors significantly associated with improved cholera KAP. In severely deconstructed social contexts, continuous education and community sensitization are crucial to achieve and maintain positive cholera prevention attitudes.

Published
2022
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