Search

Your search keyword '"Crétier, Gérard"' showing total 22 results
Start Over Author "Crétier, Gérard"
22 results on '"Crétier, Gérard"'

6. Electrochromatography on monolith in thermoplastic microchip: a robust and easy-to-use technology

Author

Ladner, Yoann, Nero Quiroz, J., Saade, J., Crétier, Gérard, Faure, Karine, TECHSEP - TECHniques de SEParations (2011-2014), Institut des Sciences Analytiques (ISA), Institut de Chimie du CNRS (INC)-Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon-Centre National de la Recherche Scientifique (CNRS)-Institut de Chimie du CNRS (INC)-Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon-Centre National de la Recherche Scientifique (CNRS), and Bussy, Agnès

Subjects
[CHIM.ANAL] Chemical Sciences/Analytical chemistry, [CHIM.ANAL]Chemical Sciences/Analytical chemistry, ComputingMilieux_MISCELLANEOUS
Abstract

International audience

Published
2014

7. Grafting method of a polymer monolith onto a substrate microfluidic device

Author

Ladner, Yoann, Bruchet, Anthony, Crétier, Gérard, RANDON, Jérôme, Faure, Karine, Institut des Sciences Analytiques (ISA), Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon-Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS), CEA- Saclay (CEA), and Commissariat à l'énergie atomique et aux énergies alternatives (CEA)

Subjects
[CHIM]Chemical Sciences
Published
2013

8. Electrochromatography on acrylate-based monolith in cyclic olefin copolymer microchip: A cost-effective and easy-to-use technology

Author

Ladner, Yoann, Crétier, Gérard, Faure, Karine, TECHSEP - TECHniques de SEParations (2011-2014), Institut des Sciences Analytiques (ISA), Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon-Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS)-Université Claude Bernard Lyon 1 (UCBL), and Université de Lyon-Université de Lyon-Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS)

Subjects
COC microchip, Biogenic Amines, Neurotransmitter Agents, CAPILLARY ELECTROCHROMATOGRAPHY, INDUCED FLUORESCENCE DETECTION, STATIONARY-PHASE, Cycloparaffins, Wine, Microfluidic Analytical Techniques, Naphthalenes, STEP, ELECTROPHORESIS, Acrylate-based monolith, Acrylates, Aflatoxins, PRECONCENTRATION, [CHIM.ANAL]Chemical Sciences/Analytical chemistry, SEPARATION, [SDV.BBM]Life Sciences [q-bio]/Biochemistry, Molecular Biology, Electrochromatography
Abstract

International audience; This article shows that there is great interest in using an electrochromatographic microchip made of hexyl acrylate (HA) based porous monolith cast within the channel of a cyclic olefin copolymer (COC) device. The monolith is simultaneously in situ synthesized and anchored to the inner walls of the channel in less than 10 min. By appropriate choice of light intensity used during the synthesis, the separation efficiency obtained for nonpolar solutes such as polycyclic aromatic hydrocarbons (PAH) is increased up to 250 000 plates/m. The performance of this HA-filled COC microchip was investigated for a wide range of analytes of varying nature. The reversed-phase separation of four aflatoxins is obtained in less than 2 min. The baseline separation of a mixture of neurotransmitters including six amino acids and two catecholamines is possible thanks to the superimposition of the differences in electrophoretic mobility on the chromatographic process. The durability of the system at pH 13 allows the separation of five biogenic amines and the quantitative determination of two of them in numerous wine samples. The feasibility of on-line preconcentration is also demonstrated. Hydrophilic surface modification of COC channel via UV-photografting with poly(ethylene glycol) methacrylate (PEGMA) before in situ synthesis of HA, is necessary to reduce the adsorption of very hydrophobic solutes such as PAH during enrichment. The detection limit of fluoranthene is decreased down to less than 1 ppb with a preconcentration of 4.5 h on the HA-filled PEGMA functionalized COC microchip.

Published
2012
Full Text
View/download PDF

9. Fabrication of acrylate monolith using photopolymerization: Effect of light intensity on electrochromatographic performance

Author

Ladner, Yoann, Crétier, Gérard, Faure, Karine, TECHSEP - TECHniques de SEParations (2011-2014), Institut des Sciences Analytiques (ISA), Institut de Chimie du CNRS (INC)-Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon-Centre National de la Recherche Scientifique (CNRS)-Institut de Chimie du CNRS (INC)-Université Claude Bernard Lyon 1 (UCBL), and Université de Lyon-Université de Lyon-Centre National de la Recherche Scientifique (CNRS)

Subjects
Light intensity, MICROCHIP, Photopolymerization, CATALYSIS, Acrylate monolith, HIGH-FLOW CHARACTERISTICS, SEPARATIONS, CHROMATOGRAPHY, STATIONARY PHASES, Cyclic olefin copolymer, ELECTROOSMOTIC FLOW, POLYMERIZATION, CHEMISTRY, [CHIM.ANAL]Chemical Sciences/Analytical chemistry, POROUS PROPERTIES, Electrochromatography
Abstract

correction: vol 35 (15) p2002; International audience; A hexyl acrylate monolith was prepared via photopolymerization into a cyclic olefin copolymer micro-device for reversed-phase electrochromatography purposes. This work deals with the influence of the irradiation conditions (irradiation time and light intensity) used during synthesis on the electrochromatographic performances of the monolithic column obtained. Up to day, the monolith structure was often controlled by means of irradiation time at constant light intensity, but the effect of light intensity (irradiance) on the monolith structure was scarcely considered. This study shows a strong effect of light intensity on electrochromatographic efficiency. Using an optimal light intensity of 4.7 mW/cm2 and an irradiation time of a few minutes allows obtaining heights equivalent to a theoretical plate reaching down to 5 mu m for the reversed-phase separation of six polycyclic aromatic hydrocarbons.

Published
2012
Full Text
View/download PDF

10. Electrochromatography on acrylate-based monolith in cyclic olefin copolymer microchip : a robust and easy-to-use technology

Author

Ladner, Yoann, Berthod, Alain, Crétier, Gérard, Faure, Karine, TECHSEP - TECHniques de SEParations (2011-2014), Institut des Sciences Analytiques (ISA), Institut de Chimie du CNRS (INC)-Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon-Centre National de la Recherche Scientifique (CNRS)-Institut de Chimie du CNRS (INC)-Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon-Centre National de la Recherche Scientifique (CNRS), and Bussy, Agnès

Subjects
[CHIM.ANAL] Chemical Sciences/Analytical chemistry, [CHIM.ANAL]Chemical Sciences/Analytical chemistry, cyclic olefin copolymer, microchip, Electrochromatography, acrylate-based monolith, ComputingMilieux_MISCELLANEOUS
Abstract

communication par affiche; International audience

Published
2012

11. One-pot method for the simultaneous synthesis and anchoring of organic monolith inside COC microchip channel

Author

Ladner, Yoann, Bruchet, Anthony, Dugas, Vincent, Randon, Jérôme, Crétier, Gérard, Faure, Karine, TECHSEP - TECHniques de SEParations (2011-2014), Institut des Sciences Analytiques (ISA), Institut de Chimie du CNRS (INC)-Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon-Centre National de la Recherche Scientifique (CNRS)-Institut de Chimie du CNRS (INC)-Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon-Centre National de la Recherche Scientifique (CNRS), and Bussy, Agnès

Subjects
[CHIM.ANAL] Chemical Sciences/Analytical chemistry, [CHIM.ANAL]Chemical Sciences/Analytical chemistry, ComputingMilieux_MISCELLANEOUS
Abstract

communication par affiche; International audience

Published
2012

12. Micro-systèmes électrochromatographiques en COC : vers la possibilité d'analyses sur site avec des analyseurs jetables

Author

Ladner, Yoann, Crétier, Gérard, Faure, Karine, Bussy, Agnès, TECHSEP - TECHniques de SEParations (2011-2014), Institut des Sciences Analytiques (ISA), Institut de Chimie du CNRS (INC)-Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon-Centre National de la Recherche Scientifique (CNRS)-Institut de Chimie du CNRS (INC)-Université Claude Bernard Lyon 1 (UCBL), and Université de Lyon-Université de Lyon-Centre National de la Recherche Scientifique (CNRS)

Subjects
[CHIM.ANAL] Chemical Sciences/Analytical chemistry, [CHIM.ANAL]Chemical Sciences/Analytical chemistry
Published
2011

21. Electrochromatography on acrylate-based monolith in cyclic olefin copolymer microchip: a cost-effective and easy-to-use technology.

Author

Ladner Y, Crétier G, and Faure K

Subjects
Aflatoxins isolation & purification, Biogenic Amines isolation & purification, Capillary Electrochromatography economics, Capillary Electrochromatography methods, Microfluidic Analytical Techniques economics, Naphthalenes chemistry, Neurotransmitter Agents isolation & purification, Wine analysis, Acrylates chemistry, Capillary Electrochromatography instrumentation, Cycloparaffins chemistry, Microfluidic Analytical Techniques instrumentation
Abstract

This article shows that there is great interest in using an electrochromatographic microchip made of hexyl acrylate (HA) based porous monolith cast within the channel of a cyclic olefin copolymer (COC) device. The monolith is simultaneously in situ synthesized and anchored to the inner walls of the channel in less than 10 min. By appropriate choice of light intensity used during the synthesis, the separation efficiency obtained for nonpolar solutes such as polycyclic aromatic hydrocarbons (PAH) is increased up to 250 000 plates/m. The performance of this HA-filled COC microchip was investigated for a wide range of analytes of varying nature. The reversed-phase separation of four aflatoxins is obtained in less than 2 min. The baseline separation of a mixture of neurotransmitters including six amino acids and two catecholamines is possible thanks to the superimposition of the differences in electrophoretic mobility on the chromatographic process. The durability of the system at pH 13 allows the separation of five biogenic amines and the quantitative determination of two of them in numerous wine samples. The feasibility of on-line preconcentration is also demonstrated. Hydrophilic surface modification of COC channel via UV-photografting with poly(ethylene glycol) methacrylate (PEGMA) before in situ synthesis of HA, is necessary to reduce the adsorption of very hydrophobic solutes such as PAH during enrichment. The detection limit of fluoranthene is decreased down to less than 1 ppb with a preconcentration of 4.5 h on the HA-filled PEGMA functionalized COC microchip., (© 2012 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.)

Published
2012
Full Text
View/download PDF

22. Fabrication of acrylate monolith using photopolymerization: effect of light intensity on electrochromatographic performance.

Author

Ladner Y, Crétier G, and Faure K

Abstract

A hexyl acrylate monolith was prepared via photopolymerization into a cyclic olefin copolymer micro-device for reversed-phase electrochromatography purposes. This work deals with the influence of the irradiation conditions (irradiation time and light intensity) used during synthesis on the electrochromatographic performances of the monolithic column obtained. Up to day, the monolith structure was often controlled by means of irradiation time at constant light intensity, but the effect of light intensity (irradiance) on the monolith structure was scarcely considered. This study shows a strong effect of light intensity on electrochromatographic efficiency. Using an optimal light intensity of 4.7 mW/cm(2) and an irradiation time of a few minutes allows obtaining heights equivalent to a theoretical plate reaching down to 5 μm for the reversed-phase separation of six polycyclic aromatic hydrocarbons., (© 2012 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.)

Published
2012
Full Text
View/download PDF

Catalog

Books, media, physical & digital resources
See catalog results