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Dichotomous views of gender and sexuality primarily categorize people according to opposing binaries – either those attracted to the 'opposite' sex (heterosexual people) or those attracted to the same sex (gay or lesbian people). This 'either/or' notion greatly stigmatizes people who exist outside of this binarized categorization due to their attraction, or lack thereof, to multiple gender identities as well as the non-binary nature of their own genders. Past scholars have coined the term 'monosexism' to describe the social and cultural structures that operate on the premise that all individuals experience attractions, and that all are (and should be) attracted to no more than one gender (Eisner, 2013; Meyer, 2019; Roberts et al., 2015). Hence, asexual, bisexual, pansexual, and other plurisexual people experience oppression rooted in the normativity of monosexuality, while heterosexual people, lesbians, and gay men–all who adhere to the societal norm of monosexuality– receive privileges. While the impacts of monosexism are evident in the literature (Kaysen et al., 2011; Walters et al., 2013), there are scholars (Hemmings & Blumenfeld, 1996; Weiss, 2004) who oppose using the term monosexism and its presumed monosexual categorization – denoting it as pejorative and divisive to the 2SLGBTQIA + community as it groups lesbians and gay men together with heterosexual people as the oppressing, monosexual group. With the increasing scholarly focus on representation and recognition of 2SLGBTQIA + individuals and communities, we contend that understanding the complexity of monosexism is important for a more clearly articulated analysis of gender and sexuality-based inequality and experience. This paper provides a critical review of scholarly perspectives discussing monosexism and at the same time, contributes to a fuller understanding of the nature of this system of oppression and discrimination. Overall, we suggest that comprehending monosexism as a neutral term to describe a social structure that oppresses all sexual identities (not just asexual and plurisexual people) can lead to better understanding and potentially to resisting and dismantling this form of oppression. [ABSTRACT FROM AUTHOR]

TERRY GOLDIE (ed.), In a Queer Country: Gay and Lesbian Studies in the Canadian Context. Vancouver: Arsenal Pulp Press, 2001, 313 p. In a Queer Country evolved from a 1997 [...]

Constitutional diseases of bone form a heterogeneous group of rare diseases of varied phenotypic presentations with a vast genetic heterogeneity. Detected mostly in childhood, they may also be diagnosed in adulthood. Medical history, clinical examination as well as biological and radiological investigations may lead to the diagnosis, which should be confirmed genetically. Joint limitations, early osteoarthritis, hip dysplasia, bone deformity, enthesopathies, bone fragility or a small height can be warning signs of a constitutional disease of bone. Establishing the diagnosis is crucial to enable optimal medical management with a specialized multidisciplinary team., Competing Interests: Les auteurs n’ont déclaré aucun conflit d’intérêts en relation avec cet article.

Introduction: Gastrointestinal stromal tumour is a pathology that originates from the interstitial cells of Cajal and differentiates from other mesenchymal neoplasm by expression of CD117 oncogene on Immunohistochemistry test. Colon and Rectal GISTs constitutes of approximately 5% of all gastrointestinal GISTs. The past decade has witnessed a dramatic change in the treatment of rectal cancer. Preoperative, perioperative and postoperative, management has changed thanks to new chemotherapy regimens and emergence of novel surgical techniques. Our aim is to investigate if same change can be implemented for rectal GISTs management., Methods and Analysis: This protocol is compliant with the Preferred Reporting Items for Systematic Review and Meta-Analysis protocols (PRISMA-P) guidelines. Exclusion and inclusion criteria are outlined within this protocol. Points of interest and objectives are described within this protocol. The search strategy, aims to identify all articles on "Rectal GISTs"., Discussion: The choice of resection type surgery depends upon the location and size of rectal GIST. Neoadjuvant Imatinib therapy yields tumour shrinkage in at least 50% and is associated with a prolonged disease-free survival for intermediate and high-risk patients. This review will also allow a summary clinicopathological features and prognostic factors of rectal GISTs., Ethics and Dissemination: The Centre for Reviews and Dissemination, University of York acknowledged that this systematic review is within the register scope. This review will be published in a peer-reviewed journal and will be presented at various national and international conferences., (© 2017 The Authors.)