2,526 results on '"Craik, David J."'
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2. Functional divergence in plant cyclotides and their role in plant defense
3. Design and structural validation of peptide–drug conjugate ligands of the kappa-opioid receptor
4. Exploring the therapeutic potential of an antinociceptive and anti-inflammatory peptide from wasp venom
5. Topology in soft and biological matter
6. Aspartic acid mutagenesis of αO-Conotoxin GeXIVA isomers reveals arginine residues crucial for inhibition of the α9α10 nicotinic acetylcholine receptor
7. Peptide PaDBS1R6 has potent antibacterial activity on clinical bacterial isolates and integrates an immunomodulatory peptide fragment within its sequence
8. Gene-guided identifications of a structure-chimeric cyclotide viphi I from Viola philippica: Potential functions against cadmium and nematodes
9. Cyclic tachyplesin I kills proliferative, non-proliferative and drug-resistant melanoma cells without inducing resistance
10. Nucleation of a key beta-turn promotes cyclotide oxidative folding
11. Scanning mutagenesis identifies residues that improve the long-term stability and insecticidal activity of cyclotide kalata B1
12. Molecular dynamics simulations support a preference of cyclotide kalata B1 for phosphatidylethanolamine phospholipids
13. Plant-based production of an orally active cyclotide for the treatment of multiple sclerosis
14. Hijacking of N-fixing legume albumin-1 genes enables the cyclization and stabilization of defense peptides
15. Bioproduction of Cyclic Disulfide-Rich Peptides for Drug Modalities
16. Cyclotides—Cyclic and Disulfide-Knotted Polypeptides
17. The Circular Bacteriocin enterocin NKR-5-3B has an Improved Stability Profile over Nisin
18. Repurposing a plant peptide cyclase for targeted lysine acylation
19. Isolation and Characterization of Insecticidal Cyclotides from Viola communis
20. Seasonal tissue-specific gene expression in wild crown-of-thorns starfish reveals reproductive and stress-related transcriptional systems
21. Sex-specific expression of pheromones and other signals in gravid starfish
22. Peptide-based LDH5 inhibitors enter cancer cells and impair proliferation
23. Towards a generic prototyping approach for therapeutically-relevant peptides and proteins in a cell-free translation system
24. A Centipede Toxin Family Defines an Ancient Class of CSαβ Defensins
25. Neurotoxic and cytotoxic peptides underlie the painful stings of the tree nettle Urtica ferox
26. Mutagenesis of bracelet cyclotide hyen D reveals functionally and structurally critical residues for membrane binding and cytotoxicity
27. Phage display-based discovery of cyclic peptides against the broad spectrum bacterial anti-virulence target CsrA
28. Comparative analysis of cyclotide-producing plant cell suspensions presents opportunities for cyclotide plant molecular farming
29. Production of a structurally validated cyclotide in rice suspension cells is enabled by a supporting biosynthetic enzyme
30. Structure and Activity of Reconstructed Pseudo‐Ancestral Cyclotides.
31. Design, Synthesis, and Structure–Activity Relationships of Novel Peptide Derivatives of the Severe Acute Respiratory Syndrome-Coronavirus‑2 Spike-Protein that Potently Inhibit Nicotinic Acetylcholine Receptors.
32. Bioproduction of Cyclic Disulfide-Rich Peptides for Drug Modalities
33. Protocols for measuring the stability and cytotoxicity of cyclotides
34. Sortase‐Catalyzed Protein Domain Inversion
35. Delivery to, and Reactivation of, the p53 Pathway in Cancer Cells Using a Grafted Cyclotide Conjugated with a Cell-Penetrating Peptide
36. The pearl jubilee of microcin J25: thirty years of research on an exceptional lasso peptide
37. Chemical synthesis of grafted cyclotides using a “plug and play” approach
38. Tertiary amide bond formation by an engineered asparaginyl ligase
39. Computational Design of α‐Conotoxins to Target Specific Nicotinic Acetylcholine Receptor Subtypes
40. The emerging landscape of peptide-based inhibitors of PCSK9
41. Effects of backbone cyclization on the pharmacokinetics and drug efficiency of the orally active analgesic conotoxin cVc1.1
42. Converting peptides into drugs targeting intracellular protein–protein interactions
43. Scalable and Efficient In Planta Biosynthesis of Sunflower Trypsin Inhibitor-1 (SFTI) Peptide Therapeutics
44. Mapping of voltage sensor positions in resting and inactivated mammalian sodium channels by LRET
45. Yeast-based bioproduction of disulfide-rich peptides and their cyclization via asparaginyl endopeptidases
46. The prospect of substrate-based kinase inhibitors to improve target selectivity and overcome drug resistance.
47. Make it or break it: Plant AEPs on stage in biotechnology
48. Deciphering the structure and mechanism of action of computer-designed mastoparan peptides.
49. Modified horseshoe crab peptides target and kill bacteria inside host cells
50. Deciphering the structure and mechanism‐of‐action of computer‐designed mastoparan peptides
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