192 results on '"Creemers, John W. M."'
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2. The proprotein convertase furin in cancer: more than an oncogene
3. Unveiling the oncogenic role of LZTS1 in colorectal cancer.
4. The proprotein convertase furin is a pro-oncogenic driver in KRAS and BRAF driven colorectal cancer
5. Epigenetic modulations of immune cells: from normal development to tumor progression.
6. Epigenetic modulations of immune cells: from normal development to tumor progression
7. Neurobeachin Gene in Autism
8. Role of Furin in Colon Cancer Stem Cells Malignant Phenotype and Expression of LGR5 and NANOG in KRAS and BRAF-Mutated Colon Tumors
9. Role of Furin in Granular Acidification in the Endocrine Pancreas: Identification of the V-ATPase Subunit Ac45 as a Candidate Substrate
10. The Authors Reply
11. The Association of Common Variants in PCSK1 With Obesity: A HuGE Review and Meta-Analysis
12. Differential Effects of Furin Deficiency on Insulin Receptor Processing and Glucose Control in Liver and Pancreatic β Cells of Mice
13. In Vivo Analysis of the Contribution of Proprotein Convertases to the Processing of FGF23
14. Control of mRNA translation preserves endoplasmic reticulum function in beta cells and maintains glucose homeostasis
15. Heterozygous mutations causing partial prohormone convertase 1 deficiency contribute to human obesity
16. Loss of Proprotein Convertase Furin in Mammary Gland Impairs proIGF1R and proIR Processing and Suppresses Tumorigenesis in Triple Negative Breast Cancer
17. Mutations in the Amino-Terminal Region of Proopiomelanocortin (POMC) in Patients with Early-Onset Obesity Impair POMC Sorting to the Regulated Secretory Pathway
18. Hyperphagia and Early-Onset Obesity due to a Novel Homozygous Missense Mutation in Prohormone Convertase 1/3
19. Agouti-Related Protein Is Posttranslationally Cleaved by Proprotein Convertase 1 to Generate Agouti-Related Protein (AGRP)83-132: Interaction between AGRP83-132 and Melanocortin Receptors Cannot Be Influenced by Syndecan-3
20. Decidual Differentiation of Stromal Cells Promotes Proprotein Convertase 5/6 Expression and Lefty Processing
21. Prodomain of Furin Promotes Phospholipid Transfer Protein Proteasomal Degradation in Hepatocytes
22. The structure of a furin-antibody complex explains non-competitive inhibition by steric exclusion of substrate conformers / The structure of a furin-antibody complex explains non-competitive inhibition by steric exclusion of substrate conformers
23. The Paired Basic Amino Acid-cleaving Enzyme 4 (PACE4) Is Involved in the Maturation of Insulin Receptor Isoform B: an opportunity to reduce the specific insulin receptor-dependent effects of insulin-like growth factor 2 (IGF2)
24. The proprotein convertase furin is a pro-oncogenic driver in KRASand BRAFdriven colorectal cancer
25. The structure of a furin-antibody complex explains non-competitive inhibition by steric exclusion of substrate conformers
26. PCSK1 Mutations and Human Endocrinopathies: From Obesity to Gastrointestinal Disorders
27. Prodomain of Furin Promotes Phospholipid Transfer Protein Proteasomal Degradation in Hepatocytes.
28. Metabolic and Behavioural Phenotypes in Nestin-Cre Mice Are Caused by Hypothalamic Expression of Human Growth Hormone
29. Liver-Specific Inactivation of the Proprotein Convertase FURIN Leads to Increased Hepatocellular Carcinoma Growth
30. The Dwarf Phenotype in GH240B Mice, Haploinsufficient for the Autism Candidate Gene Neurobeachin, Is Caused by Ectopic Expression of Recombinant Human Growth Hormone
31. PREPL deficiency: delineation of the phenotype and development of a functional blood assay
32. Trans-Golgi network morphology and sorting is regulated by prolyl-oligopeptidase-like protein PREPL and the AP-1 complex subunit μ1A
33. Generation and characterization of non-competitive furin-inhibiting nanobodies
34. Loss of Endothelial Furin Leads to Cardiac Malformation and Early Postnatal Death
35. Common nonsynonymous variants in PCSK1 confer risk of obesity
36. Position effect leading to haploinsufficiency in a mosaic ring chromosome 14 in a boy with autism
37. Global distribution of the most prevalent deletions causing hypotonia–cystinuria syndrome
38. Identification and characterization of the TRIP8 and REEP3 genes on chromosome 10q21.3 as novel candidate genes for autism
39. Proteolytic maturation and activation of autotaxin (NPP2), a secreted metastasis-enhancing lysophospholipase D
40. Curbing activation: proprotein convertases in homeostasis and pathology
41. Dynamic palmitoylation of lymphoma proprotein convertase prolongs its half-life, but is not essential for trans-Golgi network localization
42. PREPL deficiency with or without cystinuria causes a novel myasthenic syndrome.
43. Platelets of mice heterozygous for neurobeachin, a candidate gene for autism spectrum disorder, display protein changes related to aberrant protein kinase A activity.
44. Furin and proprotein convertase 7 (PC7)/lymphoma PC endogenously expressed in rat liver can be resolved into distinct post-Golgi compartments
45. Homology modelling of the catalytic domain of human furin. A model for the eukaryotic subtilisin-like proprotein convertases
46. Generation and characterization of non-competitive furin-inhibiting nanobodies.
47. Drosophila rugose Is a Functional Homolog of Mammalian Neurobeachin and Affects Synaptic Architecture, Brain Morphology, and Associative Learning.
48. Loss of Endothelial Furin Leads to Cardiac Malformation and Early Postnatal Death.
49. Human Growth Hormone in Transgenesis: A Growing Problem?
50. PREPL: a putative novel oligopeptidase propelled into the limelight.
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