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725 results on '"Croce, M"'

1. Decay Energy Spectrometry for Improved Nuclear Material Analysis at the IAEA NML

Author

Kim, G. B., Kavner, A. R. L., Parsons-Davis, T., Friedrich, S., Drury, O. B., Lee, D., Zhang, X., Hines, N., Boyd, S. T. P., Weidenbenner, S., Schreiber, K., Martinson, S., Smith, C., McNeel, D., Salazar, S., Koehler, K., Carpenter, M., Croce, M., Schmidt, D., and Ullom, J.

Subjects
Physics - Instrumentation and Detectors, Nuclear Experiment
Abstract

Decay energy spectrometry (DES) is a novel radiometric technique for high-precision analysis of nuclear materials. DES employs the unique thermal detection physics of cryogenic microcalorimeters with ultra-high energy resolution and 100$\%$ detection efficiency to accomplish high precision decay energy measurements. Low-activity nuclear samples of 1 Bq or less, and without chemical separation, are used to provide elemental and isotopic compositions in a single measurement. Isotopic ratio precisions of 1 ppm - 1,000 ppm (isotope dependent), which is close to that of the mass spectrometry, have been demonstrated in 12-hour DES measurements of ~5 Bq samples of certified reference materials of uranium (U) and plutonium (Pu). DES has very different systematic biases and uncertainties, as well as different sensitivities to nuclides, compared to mass-spectrometry techniques. Therefore, the accuracy and confidence of nuclear material assays can be improved by combining this new technique with existing mass-spectrometry techniques. Commercial-level DES techniques and equipment are being developed for the implementation of DES at the Nuclear Material Laboratory (NML) of International Atomic Energy Agency (IAEA) to provide complementary measurements to the existing technologies. The paper describes details of DES measurement methods, as well as DES precision and accuracy to U and Pu standard sources to discuss its capability in analysis of nuclear safeguards samples., Comment: This was submitted to 2022 IAEA symposium on nuclear safeguards (https://www.iaea.org/events/sg-2022), and posted at https://media.superevent.com/documents/20221027/668fdac0ee8d895ec6bcf293b1c42e6a/id-145.pdf

Published
2024

4. Spent Fuel Measurements

Author

Kaplan-Trahan, A. C., Belian, A. P., Croce, M., Henzlova, D. C., Jansson, P., Long, G., McMath, G. E., Phillips, J. R., Rapisarda, E., Root, M. A., Trellue, H. R., Geist, William H., editor, Santi, Peter A., editor, and Swinhoe, Martyn T., editor

Published
2024
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6. Calorimetric Assay Instruments

Author

Croce, M. P., Bracken, D. S., Brochard, X., Likes, R. N., Rudy, C. R., Santi, P. A., Geist, William H., editor, Santi, Peter A., editor, and Swinhoe, Martyn T., editor

Published
2024
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8. Gamma and Decay Energy Spectroscopy Measurements of Trinitite

Author

Mercer, D. J., Koehler, K. E., Croce, M. P., Hoover, A. S., Hypes, P. A., Kozimor, S. A., Mocko, V., and Saey, P. R. J.

Subjects
Physics - History and Philosophy of Physics, Physics - Physics and Society
Abstract

We report gamma ray spectroscopy measurements of trinitite samples and analogous samples obtained from detonation sites in Nevada and Semipalatinsk, as well as in situ measurements of topsoil at the Trinity site. We also report the first isotopic composition measurements of trinitite using the novel forensics technique of decay energy spectroscopy (DES) as a complement to traditional forensics techniques. Our measurements are compared to other published results.

Published
2021

13. Development of holmium-163 electron-capture spectroscopy with transition-edge sensors

Author

Croce, M. P., Rabin, M. W., Mocko, V., Kunde, G. J., Birnbaum, E. R., Bond, E. M., Engle, J. W., Hoover, A. S., Nortier, F. M., Pollington, A. D., Taylor, W. A., Weisse-Bernstein, N. R., Wolfsberg, L. E., Hays-Wehle, J. P., Schmidt, D. R., Swetz, D. S., Ullom, J. N., Barnhart, T. E., and Nickles, R. J.

Subjects
Physics - Instrumentation and Detectors, Nuclear Experiment
Abstract

Calorimetric decay energy spectroscopy of electron-capture-decaying isotopes is a promising method to achieve the sensitivity required for electron neutrino mass measurement. The very low total nuclear decay energy (QEC < 3 keV) and short half-life (4570 y) of 163Ho make it attractive for high-precision electron capture spectroscopy (ECS) near the kinematic endpoint, where the neutrino momentum goes to zero. In the ECS approach, an electron-capture-decaying isotope is embedded inside a microcalorimeter designed to capture and measure the energy of all the decay radiation except that of the escaping neutrino. We have developed a complete process for proton-irradiation-based isotope production, isolation, and purification of 163Ho. We have developed transition-edge sensors for this measurement and methods for incorporating 163Ho into high-resolution microcalorimeters, and have measured the electron-capture spectrum of 163Ho. We present our work in these areas and discuss the measured spectrum and its comparison to current theory., Comment: Updated with corrected notation for atomic states

Published
2015
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14. Hyperspectral X-ray Imaging with TES Detectors for Nanoscale Chemical Speciation Mapping

Author

Carpenter, M. H., Croce, M. P., Baker, Z. K., Batista, E. R., Caffrey, M. P., Fontes, C. J., Koehler, K. E., Kossmann, S. E., McIntosh, K. G., Rabin, M. W., Renck, B. W., Wagner, G. L., Wilkerson, M. P., Yang, P., Yoho, M. D., Ullom, J. N., Bennett, D. A., O’Neil, G. C., Reintsema, C. D., Schmidt, D. R., Hilton, G. C., Swetz, D. S., Becker, D. T., Gard, J. D., Imrek, J., Mates, J. A. B., Morgan, K. M., Yan, D., Wessels, A. L., Cantor, R. H., Hall, J. A., and Carver, D. T.

Published
2020
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22. A 760-nW, 180-nm CMOS Fully Analog Voice Activity Detection System for Domestic Environment

Author

Croce, M, Friend, B, Nesta, F, Crespi, L, Malcovati, P, Baschirotto, A, Croce M., Friend B., Nesta F., Crespi L., Malcovati P., Baschirotto A., Croce, M, Friend, B, Nesta, F, Crespi, L, Malcovati, P, Baschirotto, A, Croce M., Friend B., Nesta F., Crespi L., Malcovati P., and Baschirotto A.

Abstract

This article presents a fully analog, signal-to-noise-ratio-based voice-activity detection (VAD) circuit. The circuit is based on an energy-efficient analog implementation with continuous-time nonlinear operation and fully passive switched-capacitor signal processing. The overall chain is composed of a programmable-gain amplifier, a squarer, an integrator, an SC-based signal averaging circuit, and a periodic threshold update circuit for adaptability. This implementation allows the minimization of both power consumption and chip area. The VAD circuit prototype has been fabricated in a 180-nm CMOS technology and occupies an area of 0.14 mm2. The device achieves 99.5% classification accuracy in a domestic environment in the presence of loud ambient noise, consuming 760 nW from a 1.2-V supply.

Published
2021

27. A 760 nW, 180 nm CMOS Analog Voice Activity Detection System

Author

Croce, M, Friend, B, Nesta, F, Crespi, L, Malcovati, P, Baschirotto, A, Croce M., Friend B., Nesta F., Crespi L., Malcovati P., Baschirotto A., Croce, M, Friend, B, Nesta, F, Crespi, L, Malcovati, P, Baschirotto, A, Croce M., Friend B., Nesta F., Crespi L., Malcovati P., and Baschirotto A.

Abstract

This paper presents a fully analog, signal-to-noise ratio (SNR) based voice-activity detection circuit, which achieves 99.5 % classification accuracy in a domestic environment in the presence of loud ambient noise, consuming 760 nW from a 1.2 V supply. The circuit exploits an energy-efficient analog implementation with continuous-time non-linear operation and fully-passive switched-capacitor processing, to minimize both the power consumption and the chip area. The VAD circuit prototype, fabricated in a 180 nm CMOS technology, occupies 0.14mm2.

Published
2020

28. Un'esperienza molteplice del bene: fra percezione e pratica del valore morale

Author

Langella, S, Vaccarezza, MS, Croce, M, Monti, P, Langella, S, Vaccarezza, MS, Croce, M, and Monti, P

Abstract

Nel saggio si considera analiticamente la categoria di "esperienza integrale" a partire dalla sua espressione nell'opera di Angelo Campodonico e se ne propone un'analisi critica nel confronto con alcune voci del dibattito internazionale (R. Audi, A. MacIntyre, J. Raz, M. Nussbaum). A tale scopo, la categoria viene discussa a partire da tre aree problematiche: il rapporto fra esperienza assiologica e percezione morale, la presenza della ricerca di senso nelle pratiche sociali, la tensione fra esperienza religiosa ed etica pubblica., The essay analytically considers the category of "integral experience" starting from its expression in the work of Angelo Campodonico and proposes a critical analysis in comparison with some voices of the international debate (R. Audi, A. MacIntyre, J. Raz, M. Nussbaum). To this end, the category is discussed starting from three problematic areas: the relationship between axiological experience and moral perception, the presence of the search for meaning in social practices, the tension between religious experience and public ethics.

Published
2022

40. Massa 2022 - Book of Abstracts

Author

Di Francesco, G., Croce, M., Vincenti, F., Montesano, C., Sergi, M., and Curini, R.

Subjects
Suspect Screening, Novel Psychoactive Substances, Mass Spectrometry, Suspect Screening, Novel Psychoactive Substances, Mass Spectrometry
Published
2022

45. 673P Magnetization transfer imaging in late-onset Pompe disease.

Author

Croce, M., Naz, F., Barzaghi, L., Paoletti, M., Mongini, T., Gasperini, S., Filosto, M., Maggi, L., Sechi, A., Grandis, M., Sacchini, M., Sciacco, M., Vercelli, L., Bonizzoni, C., Bergsland, N., Santini, F., Deligianni, X., Ravaglia, S., and Pichiecchio, A.

Subjects
*MAGNETIZATION transfer, *GLYCOGEN storage disease type II, *CENTRAL nervous system diseases, *DISEASE progression, *MACROMOLECULES
Abstract

Magnetization transfer imaging (MTI) evaluates the exchange of magnetization between protons in free water molecules and protons bound to macromolecules, including lipids. Widely used in the study of central nervous system diseases, its application in the neuromuscular field has been previously explored only in a Spanish cohort of patients with late-onset Pompe disease (LOPD). To investigate the potential role of MTR as an early biomarker of muscle involvement, we here evaluate magnetization transfer ratio (MTR) and fat fraction (FF) in patients with LOPD in various stages of disease compared to healthy controls (HCs). Quantitative muscle MRI (qMRI) was performed on 31 LOPD patients (21 with mild and 10 with moderate/severe clinical involvement) and 31 matched HCs using 3T MRI. FF and MTR were measured in 11 thigh muscles. Correlations between FF and MTR were assessed. Additionally, FF and MTR were compared between groups of HCs vs. early vs. moderate/severe LOPD. We also explored whether MTR can detect muscle involvement in not yet fat-infiltrated muscles (FF ≤ 10%) in early LOPD. MTR of thigh muscles with FF ≤ 10% was significantly lower in LOPD compared to HCs. Changes in MTR could be detected even in mildly symptomatic patients, particularly in the medial and posterior compartments (Mann-Whitney U: p < 0.05). MTR and FF were inversely correlated in all subjects groups. We found significant differences in MTR and FF changes at the group level between mild and moderate/severe vs HCs. We conclude that MTI has potentially high sensitivity to detect mild muscle fiber damage, even before fat replacement has occurred, making it a useful biomarker to monitor early signs of disease, disease progression, and the efficacy of treatment approaches (Sanofi company provided support for this study, but had no role in study design, data collection and analysis, decision to publish, or preparation of the abstract). (The first and second authors contributed equally to this work) [ABSTRACT FROM AUTHOR]

Published
2024
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