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Objective To investigate and analyze the situation of hospital acquired infection in surgical ward of Guizhou Province in 2022, and to provide direction and method for improving the prevention and control of hospital acquired infection. Methods The prevalence of hospital acquired infection in surgical wards of 186 medical institutions in the province from July to December 2022 was investigated by means of a cross - sectional survey and bedside survey combined with inpatient records. Results A total of 27 046 patients were investigated, and 504 cases of hospital acquired infection occurred. The prevalence rate of hospital acquired infection was 1.86%, neurosurgery (4, 43%) and cardio 一 thoracic surgery (3, 25%) were the highest, and the difference of infection rate among different surgical systems was statistically significant (2 = 157.980, P < 0.001). The main site of hospital acquired infection was respiratory tract (0. 99%), surgical site (0. 50%), skin and soft tissue (0. 24%), and the incidence rate of different infection sites was statistically significant(P <0. 05). The prevalence rate of hospital acquired infection in Class I incision was 3. 42%. The highest utilization rate of antibiotics was 40. 72% in cardio 一 thoracic surgery (13. 01%) and neurosurgery (11. 64%). The hospital acquired infection rate of Class I incision in different departments was significantly different (2 = 186. 607, P < 0. 001). The main purpose of medication in surgical ward was treatment (26. 10%), and the rate of pre 一 medication examination in surgical ward was 33.41% for single medication (36. 06%). Conclusion The incidence rate of hospital acquired infection in surgical ward shows a decreasing trend. Cardio 一 thoracic surgery and neurosurgery are still the most common departments causing hospital acquired infection of respiratory tract and incision 一 like surgical site infection. [ABSTRACT FROM AUTHOR]

Obiective To investigate the current status of remaining teeth and edentulous jaw arch of people aged 35⁃44, 55⁃64 and 65⁃ 74 in Guangdong province. Methods An equal⁃ sized stratified multi⁃stage randomly sampling design was applied to select a total of 288 Guangdong residents in urban and rural areas, and the subjects were between the age of 35⁃44, 55⁃64 and 65⁃74, with a gender ratio of half to half. The status of remaining teeth and edentulous jaw arch were assessed according to the Guideline for the 4th National Oral Health Survey. Results 88.89% subjects in the 35⁃44 year group had more than 28 teeth and 100% subjects had more than 20 teeth, with an average of 29.88 teeth remaining and no edentulous jaw. The average remaining teeth was 26.06 in the group of 55 ⁃ 64 year, with 87.50% subjects having more than 20 teeth, 59.03% subjects having 28 or more teeth, 4.16% subjects having single edentulous jaw arch, and 1.04% subjects having both edentulous jaw arch. 73.96% and 35.07% subjects in the group of 65⁃74 year had 20 above or 28 above remaining teeth, respectively, and the average teeth was 22.94. There were 8.34% subjects having single edentulous jaw arch and 1.39% subjects having both edentulous jaws. In the 35⁃44 and 65⁃74 year group, the prevalence of missing teeth in the female was significantly higher than the male (P < 0.05), while no significant difference was found between urban and rural areas (P > 0.05). More remaining teeth were noticed in current survey (2015) when compared to the data in 2005 (P < 0.05). Conclusion The 35⁃44 year people have few lost teeth, and over half of the elderly people have several lost teeth. Elderly people with edentulous arch are very few.

Objective This study aimed to describe self-reported patterns of use and effects of lysergic acid diethylamide (LSD) analogues (AL-LAD, 1P-LSD, and ETH-LAD) and the characteristics of those who use them. Methods An anonymous self-selected online survey of people who use drugs (Global Drug Survey 2016; N = 96,894), which measured perceived drug effects of LSD and its analogues. Results Most LSD analogue users (91%) had also tried LSD. The proportion of U.K. and U.S. respondents reporting LSD analogue use in the last 12 months was higher than for LSD only. LSD analogue users described the effects as psychedelic (93%), over half (55%) obtained it online, and almost all (99%) reported an oral route of administration. The modal duration (8 hr) and time to peak (2 hr) of LSD analogues were not significantly different from LSD. Ratings for pleasurable high, strength of effect, comedown, urge to use more drugs, value for money, and risk of harm following use were significantly lower for LSD analogues compared with LSD. Conclusions LSD analogues were reported as similar in time to peak and duration as LSD but weaker in strength, pleasurable high, and comedown. Future studies should seek to replicate these findings with chemical confirmation and dose measurement. [ABSTRACT FROM AUTHOR]

Schmallenberg virus ( SBV), which emerged in Northwestern Europe in 2011, is an arthropod-borne virus affecting primarily ruminants. Based on the results of two cross-sectional studies conducted in the Belgian ruminant population during winter 2011-2012, we concluded that at the end of 2011, almost the whole population had already been infected by SBV. A second cross-sectional serological study was conducted in the Belgian cattle population during winter 2012-2013 to examine the situation after the 2012 transmission period and to analyse the change in immunity after 1 year. A total of 7130 blood samples collected between 1st January and 28 February 2013 in 188 herds were tested for the presence of SBV-specific antibodies. All sampled herds tested positive and within-herd seroprevalence was estimated at 65.66% (95% CI: 62.28-69.04). A statistically significant decrease was observed between the beginning and the end of 2012. On the other hand, age-cohort-specific seroprevalence stayed stable from 1 year to the other. During winter 2012-2013, calves between 6 and 12 months had a seroprevalence of 20.59% (95% CI: 15.34-25.83), which seems to be an indication that SBV was still circulating at least in some parts of Belgium during summer-early autumn 2012. Results showed that the level of immunity against SBV of the animals infected has not decreased and remained high after 1 year and that the spread of the virus has slowed down considerably during 2012. This study also indicated that in the coming years, there are likely to be age cohorts of unprotected animals. [ABSTRACT FROM AUTHOR]

A cross-sectional survey was conducted in the Belgian cattle population after the first period of infection of the emerging Schmallenberg virus. A total number of 11 635 cattle from 422 herds sampled between 2 January and 7 March 2012 were tested for the presence of Schmallenberg-specific antibodies using an ELISA kit. Between-herd seroprevalence in cattle was estimated at 99.76% (95% CI: 98.34-99.97) and within-herd seroprevalence at 86.3% (95% CI: 84.75-87.71). An Intraclass Correlation Coefficient of 0.3 ( P < 0.001) was found, indicating that the correlation between two animals within a herd with respect to their serological status was high. Those results corroborate the conclusion that the Schmallenberg virus was widespread in Belgium during winter 2011. Seroprevalence was shown to be statistically associated to the animal's age ( P < 0.0001): with 64.9% (95% CI: 61.34-68.3) estimated for the 6-12 months of age, 86.79% (95% CI: 84.43-88.85) for the 12-24 months of age and 94.4% (95% CI: 93.14-95.44) for the animals older than 24 months. Based on the results of the described serological survey, we can conclude that after the first Schmallenberg virus episode, almost every Belgian cattle has already been in contact with the virus. In consequence, the vast majority of the host animals should have developed post infection protective immunity against the virus. [ABSTRACT FROM AUTHOR]