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3. Biosafety in Dental Health Care During the COVID-19 Pandemic: A Longitudinal Study

Author

Miguita, Lucyene, primary, Martins-Chaves, Roberta Rayra, additional, Geddes, Victor Emmanuel Viana, additional, Mendes, Suellen da Rocha, additional, Costa, Sara Ferreira dos Santos, additional, Fonseca, Paula Luize Camargos, additional, Menezes, Diego, additional, Souza, Rafael Marques de, additional, Queiroz, Daniel Costa, additional, Alves, Hugo José, additional, Freitas, Raphaela Alvarenga Braga de, additional, Cruz, Aline Fernanda, additional, Moreira, Rennan Garcias, additional, Moreira, Filipe Romero Rebello, additional, Bemquerer, Larissa Marques, additional, Aguilar, Diego Rodrigues de, additional, Souza e Silva, Maria Elisa de, additional, Sampaio, Aline Araújo, additional, Jardilino, Francisca Daniele Moreira, additional, Souza, Leandro Napier de, additional, Silva, Tarcilia Aparecida da, additional, Gomes, Carolina Cavaliéri, additional, de Abreu, Mauro Henrique Nogueira Guimarães, additional, Aguiar, Renato Santana de, additional, Souza, Renan Pedra de, additional, and Gomez, Ricardo Santiago, additional

Published
2022
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8. Unveiling metabolic changes in marsupialized odontogenic keratocyst: A pilot study.

Author

Leite‐Lima, Flávia, Bastos, Victor Coutinho, Vitório, Jéssica Gardone, Duarte‐Andrade, Filipe Fideles, Pereira, Thaís dos Santos Fontes, Martins‐Chaves, Roberta Rayra, Cruz, Aline Fernanda, de Lacerda, Júlio César Tanos, Lebron, Yuri Abner Rocha, Moreira, Victor Rezende, Santos, Lucilaine Valéria de Souza, Lange, Liséte Celina, de Macedo, Adriana Nori, Diniz, Marina Gonçalves, Gomes, Carolina Cavaliéri, de Castro, Wagner Henriques, Canuto, Gisele André Baptista, and Gomez, Ricardo Santiago

Subjects
PILOT projects, HIGH performance liquid chromatography, METABOLOMICS, FORMALDEHYDE, METABOLISM, MASS spectrometry, DESCRIPTIVE statistics, ODONTOGENIC cysts, ORAL mucosa
Abstract

Objective: We aimed to assess which metabolic pathways would be implicated in the phenotypic changes of the epithelial lining of odontogenic keratocyst after marsupialization, comparing pre‐ and post‐marsupialized lesions with adjacent oral mucosa. Materials and Methods: Eighteen formalin‐fixed and paraffin‐embedded tissues from six subjects were divided into three paired groups: odontogenic keratocyst pre‐ (n = 6) and post‐marsupialization (n = 6), and adjacent oral mucosa (n = 6). The metabolic pathways found in these groups were obtained by high‐performance liquid chromatography‐mass spectrometry‐based untargeted metabolomics performed. Results: Through putative metabolite annotation followed by pathway enrichment and predictive analysis with automated algorithms (Mummichog and Gene Set Enrichment Analysis), we found differences in many cellular processes that may be involved in inflammation, oxidative stress response, keratinocyte‐basal membrane attachment, differentiation, and proliferation functions, all relevant to odontogenic keratocyst pathobiology and the phenotype acquired after marsupialization. Conclusion: Our study was able to identify several metabolic pathways potentially involved in the metaplastic changes induced by marsupialization of odontogenic keratocysts. An improved comprehension of this process could pave the way for the development of targeted therapies. [ABSTRACT FROM AUTHOR]

Published
2022
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9. Unveiling metabolic changes in marsupialized odontogenic keratocyst: A pilot study

Author

Leite‐Lima, Flávia, primary, Bastos, Victor Coutinho, additional, Vitório, Jéssica Gardone, additional, Duarte‐Andrade, Filipe Fideles, additional, Pereira, Thaís dos Santos Fontes, additional, Martins‐Chaves, Roberta Rayra, additional, Cruz, Aline Fernanda, additional, de Lacerda, Júlio César Tanos, additional, Lebron, Yuri Abner Rocha, additional, Moreira, Victor Rezende, additional, Santos, Lucilaine Valéria de Souza, additional, Lange, Liséte Celina, additional, de Macedo, Adriana Nori, additional, Diniz, Marina Gonçalves, additional, Gomes, Carolina Cavaliéri, additional, de Castro, Wagner Henriques, additional, Canuto, Gisele André Baptista, additional, and Gomez, Ricardo Santiago, additional

Published
2021
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10. Biosafety in Dental Health Care During Covid-19 Pandemic: A Longitudinal Study

Author

Miguita, Lucyene, primary, Martins-Chaves, Roberta Rayra, additional, Geddes, Victor Emmanuel Viana, additional, Mendes, Suellen da Rocha, additional, Costa, Sara Ferreira dos Santos, additional, Menezes, Diego, additional, Fonseca, Paula Luize Camargos, additional, Souza, Rafael Marques de, additional, Queiroz, Daniel Costa, additional, Alves, Hugo José, additional, Freitas, Raphaela Alvarenga Braga de, additional, Cruz, Aline Fernanda, additional, Moreira, Rennan Garcias, additional, Moreira, Filipe Romero Rebello, additional, Bemquerer, Larissa Marques, additional, de Aguilar, Diego Rodrigues, additional, Souza e Silva, Maria Elisa de, additional, Sampaio, Aline Araujo, additional, Silami, Francisca Daniele Jardilino, additional, de Souza, Leandro Napier, additional, Silva, Tarcilia Aparecida da, additional, Gomes, Carolina Cavaliéri, additional, de Abreu, Mauro Henrique Nogueira Guima, additional, Aguiar, Renato Santana de, additional, de Souza, Renan Pedra, additional, and Gomez, Ricardo Santiago, additional

Published
2021
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11. Dental Implants in Patients with Oral Lichen Planus : A Systematic Review

Author

Chrcanovic, Bruno Ramos, Cruz, Aline Fernanda, Trindade, Ricardo, Gomez, Ricardo Santiago, Chrcanovic, Bruno Ramos, Cruz, Aline Fernanda, Trindade, Ricardo, and Gomez, Ricardo Santiago

Abstract

Background and Objectives: To integrate the available published data on patients with oral lichen planus (OLP) rehabilitated with dental implants, as well as to review the recommendations for OLP patients receiving implants. Materials and Methods: An electronic search was undertaken in February 2019 using five databases. Publications reporting cases of patients with OLP and rehabilitated with implant-supported oral prosthesis were included. Results: Twenty-two publications were included (230 patients, 615 implants). The overall implant failure rate was 13.9% (85/610). In patients with oral squamous cell carcinoma (OSCC) the failure rate was 90.6% (29/32), but none of these implants lost osseointegration; instead, the implants were removed together with the tumor. One study presented a very high implant failure rate, 76.4% (42/55), in patients with “active lichen planus”, with all implants failing between 7–16 weeks after implant placement, and its conflicting and incongruent results are discussed in detail. There was a statistically significant difference between the failure rates in implants installed in different jaws (maxilla/mandible) and when implants of different surfaces were used (turned/moderately rough), but not between patients with reticular or erosive OLP types, or between male and female patients. If OSCC patients and the cases of the latter study are not considered, then the failure rate becomes very low (2.7%, 14/523). The time between implant placement and failure was 25.4 ± 32.6 months (range 1–112). The mean ± SD follow-up was 58.9 ± 26.7 months (1–180). Conclusions: When the results of the one study with a very high failure rate and of the cases that developed OSCC are not considered, the dental implant failure rate in OLP patients was 2.7% after a follow-up of approximately five years. Recommendations are given when treating OLP patients with dental implants.

Published
2020
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15. CONSERVATIVE APPROACH OF ORTHOKERATINIZED CYST: A CASE REPORT

Author

SANTOS, ANDRESSA FARIA, primary, DE ARAÚJO, GABRIELA RIBEIRO, additional, CRUZ, ALINE FERNANDA, additional, DE MACEDO, LARISSA CAVALCANTI, additional, DE RESENDE, RENATA GONÇALVES, additional, RODRIGUES, LORRANY GABRIELA, additional, and DE LACERDA, JÚLIO CÉSAR TANOS, additional

Published
2020
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16. LATERAL PERIODONTAL CYST: A CASE REPORT

Author

DA MOTA, BÁRBARA GABRIELLE BOMFIM, primary, CRUZ, ALINE FERNANDA, additional, FONSECA, ALICE SOUZA VILLAR CASSIMIRO, additional, REZENDE, RENATA GONÇALVES, additional, MARCIAL, JULIANA PERÍGOLO, additional, FONSECA, FELIPE PAIVA, additional, and GOMEZ, RICARDO SANTIAGO, additional

Published
2020
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17. PILOMATRICOMA IN A CHILD: A CASE REPORT

Author

ROCHA, NATÁLIA CARVALHO SANTANA, primary, RESENDE, RENATA GONÇALVES, additional, CRUZ, ALINE FERNANDA, additional, AMARAL, SÉRGIO ANTONUCCI, additional, GOMES, NATÁLIA APARECIDA, additional, SILVA, TARCÍLIA APARECIDA, additional, and DE LACERDA, JÚLIO CÉSAR TANOS, additional

Published
2020
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18. ASSOCIATION OF STRESS AND ORAL LESIONS

Author

CRUZ, ALINE FERNANDA, primary, DE SOUZA CARVALHO, BETHANIA CAROLINA, additional, DE LACERDA, JÚLIO CÉSAR TANOS, additional, CARNEIRO, MARYÊ CARVALHO, additional, DOS SANTOS, PHILLIPPE VIEIRA, additional, CARNEIRO, ALINE CRISTINA, additional, and RESENDE, RENATA GONÇALVES, additional

Published
2020
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19. MUCORMYCOSIS IN THE IMMUNOCOMPROMISED HOST: A CASE REPORT

Author

CRUZ, ALINE FERNANDA, primary, DE SOUZA PINTO, LÍVIA SÂMARA FRANCIELLE, additional, DE LACERDA, JÚLIO CÉSAR TANOS, additional, DOS SANTOS, ISABELA FERNANDES, additional, BOTELHO, SÉRGIO HENRIQUE BENFENATTI, additional, FONSECA, FELIPE PAIVA, additional, and RESENDE, RENATA GONÇALVES, additional

Published
2020
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22. Reticular and erosive oral lichen planus have a distinct metabolomic profile: A preliminary study using gas chromatography‐mass spectrometry

Author

Cruz, Aline Fernanda, primary, Vitório, Jéssica Gardone, additional, Duarte‐Andrade, Filipe Fideles, additional, Diniz, Marina Gonçalves, additional, Canuto, Gisele André Baptista, additional, Toledo, Juliano Simões, additional, Fonseca, Felipe Paiva, additional, Fernandes, Ana Paula, additional, André, Leiliane Coelho, additional, Gomes, Carolina Cavaliéri, additional, and Gomez, Ricardo Santiago, additional

Published
2019
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25. Kaposi Sarcoma in an HIV-Negative Patient

Author

Cruz, Aline Fernanda, primary, Araújo, José Augusto Dias, additional, Costa, Samuel Macedo, additional, De Lacerda, Júlio César Tanos, additional, Caldeira, Patrícia Carlos, additional, Mesquita, Ricardo Alves, additional, and Resende, Renata Gonçalves, additional

Published
2018
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26. Atypical Oral Squamous Cell Carcinoma at Two Different Sites

Author

Barbosa Silva, André Myller, primary, Resende, Renata Gonçalves, additional, Cruz, Aline Fernanda, additional, Silva, Tarcília Aparecida, additional, Winkelstroter, Lorenna Kretli, additional, Lopes De Paiva, Rejane Christina, additional, and Tanos Lacerda, Júlio César, additional

Published
2018
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29. ADENOMATOID ODONTOGENIC TUMOR: REPORT OF A CASE

Author

BARBOSA SILVA, ANDRÉ MYLLER, primary, CRUZ, ALINE FERNANDA, additional, ALVES, PAULA JULIENE TELES, additional, DE ALBUQUERQUE, DANIEL RICALDONI, additional, DE AGUIAR, MARIA CÁSSIA FERREIRA, additional, RESENDE, RENATA GONÇALVES, additional, and DE LACERDA, JÚLIO CÉSAR TANOS, additional

Published
2017
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31. DESMOPLASTIC FIBROMA: A CASE REPORT

Author

CRUZ, ALINE FERNANDA, primary, FERREIRA, THAÍS LEMOS, additional, AZEVEDO, MARIANA NEVES DE, additional, DE JESUS, ALESSANDRO OLIVEIRA, additional, DE LACERDA, JULIO CÉSAR TANOS, additional, CRUZ, NAYARA SOUZA, additional, and DE RESENDE, RENATA GONÇALVES, additional

Published
2017
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34. Mucosal Leishmaniasis

Author

LEITE, CAMILA FERREIRA, primary, RESENDE, RENATA GONÇALVES, additional, DE LACERDA, JÚLIO CÉSAR TANOS, additional, CRUZ, ALINE FERNANDA, additional, and DE AGUIAR, MARIA CÁSSIA FERREIRA, additional

Published
2015
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35. Solitary Fibrous Tumor

Author

DE RESENDE, RENATA GONÇALVES, primary, DE LACERDA, JÚLIO CÉSAR TANOS, additional, CRUZ, ALINE FERNANDA, additional, DE FÁTIMA BERNARDES, VANESSA, additional, and GOMEZ, RICARDO SANTIAGO, additional

Published
2015
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36. Dental Implants in Patients with Oral Lichen Planus: A Systematic Review.

Author

Chrcanovic BR, Cruz AF, Trindade R, and Gomez RS

Subjects
Adult, Dental Implants standards, Female, Humans, Lichen Planus, Oral physiopathology, Male, Middle Aged, Mouth Neoplasms etiology, Mouth Neoplasms physiopathology, Dental Implants adverse effects, Lichen Planus, Oral etiology
Abstract

Background and Objectives: To integrate the available published data on patients with oral lichen planus (OLP) rehabilitated with dental implants, as well as to review the recommendations for OLP patients receiving implants. Materials and Methods : An electronic search was undertaken in February 2019 using five databases. Publications reporting cases of patients with OLP and rehabilitated with implant-supported oral prosthesis were included. Results : Twenty-two publications were included (230 patients, 615 implants). The overall implant failure rate was 13.9% (85/610). In patients with oral squamous cell carcinoma (OSCC) the failure rate was 90.6% (29/32), but none of these implants lost osseointegration; instead, the implants were removed together with the tumor. One study presented a very high implant failure rate, 76.4% (42/55), in patients with "active lichen planus", with all implants failing between 7-16 weeks after implant placement, and its conflicting and incongruent results are discussed in detail. There was a statistically significant difference between the failure rates in implants installed in different jaws (maxilla/mandible) and when implants of different surfaces were used (turned/moderately rough), but not between patients with reticular or erosive OLP types, or between male and female patients. If OSCC patients and the cases of the latter study are not considered, then the failure rate becomes very low (2.7%, 14/523). The time between implant placement and failure was 25.4 ± 32.6 months (range 1-112). The mean ± SD follow-up was 58.9 ± 26.7 months (1-180). Conclusions : When the results of the one study with a very high failure rate and of the cases that developed OSCC are not considered, the dental implant failure rate in OLP patients was 2.7% after a follow-up of approximately five years. Recommendations are given when treating OLP patients with dental implants., Competing Interests: The authors declare no conflict of interest.

Published
2020
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