Search

Your search keyword '"Cruz, Vitória P. D."' showing total 2 results
Start Over Author "Cruz, Vitória P. D."
2 results on '"Cruz, Vitória P. D."'

1. Arterial stiffness in black adults from Angola and Brazil

Author

Cruz, Vitória P. D., primary, Gonzaga, Carla W. O., additional, Silva, Victor B., additional, Cruz, André F. P., additional, Silva, Amilcar B. Tomé, additional, Capingana, Daniel P., additional, Magalhães, Pedro, additional, Zaniqueli, Divanei A., additional, Guimarães, André L. S., additional, Cunha, Roberto Sá, additional, Mill, José Geraldo, additional, and Baldo, Marcelo P., additional

Published
2020
Full Text
View/download PDF

2. Immunohistochemical analysis of TIMP-3 and MMP-9 in actinic keratosis, squamous cell carcinoma of the skin, and basal cell carcinoma.

Author

Poswar FO, Fraga CA, Farias LC, Feltenberger JD, Cruz VP, Santos SH, Silveira CM, de Paula AM, and Guimarães AL

Subjects
Adult, Aged, Carcinoma, Basal Cell pathology, Carcinoma, Squamous Cell pathology, Female, Humans, Keratosis, Actinic pathology, Male, Middle Aged, Neoplasm Invasiveness, Skin Neoplasms pathology, Biomarkers, Tumor analysis, Carcinoma, Basal Cell enzymology, Carcinoma, Squamous Cell enzymology, Immunohistochemistry, Keratosis, Actinic enzymology, Matrix Metalloproteinase 9 analysis, Skin Neoplasms enzymology, Tissue Inhibitor of Metalloproteinase-3 analysis
Abstract

The expression of metalloproteinases and their inhibitors has been related to different invasive and metastatic potentials in cancer. This study aims to investigate the immunohistochemical expression of TIMP-3 and MMP-9 in samples of basal cell carcinoma (BCC), squamous cell carcinoma of the skin (SCC), and actinic keratosis (AK). Immunohistochemistry was performed to evaluate the expression of TIMP-3 and MMP-9 in samples of BCC (n=22), SCC (n=10), and AK (n=15). Ten fields of both tumor parenchyma and tumor stroma were photographed and counted in image software. The ratio of positive cells to total cells was used to quantify the staining. A higher expression of MMP-9 was found in tumor stroma of SCC compared to BCC and AK. No significant differences in TIMP-3 expression were observed among the groups. Considering the well-described differences between these neoplasms, these results provide additional evidence of the role of MMP-9 in tumor invasiveness of keratinocyte-derived tumors., (Copyright © 2013 Elsevier GmbH. All rights reserved.)

Published
2013
Full Text
View/download PDF

Catalog

Books, media, physical & digital resources
See catalog results