5,272 results on '"Cuenca, P."'
Search Results
2. Relational Graph Convolutional Networks Do Not Learn Sound Rules
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Morris, Matthew, Cucala, David J. Tena, Grau, Bernardo Cuenca, and Horrocks, Ian
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Computer Science - Machine Learning ,Computer Science - Artificial Intelligence ,Computer Science - Logic in Computer Science ,03B70 ,I.2.6 ,G.2.2 ,I.2.4 ,I.2.3 - Abstract
Graph neural networks (GNNs) are frequently used to predict missing facts in knowledge graphs (KGs). Motivated by the lack of explainability for the outputs of these models, recent work has aimed to explain their predictions using Datalog, a widely used logic-based formalism. However, such work has been restricted to certain subclasses of GNNs. In this paper, we consider one of the most popular GNN architectures for KGs, R-GCN, and we provide two methods to extract rules that explain its predictions and are sound, in the sense that each fact derived by the rules is also predicted by the GNN, for any input dataset. Furthermore, we provide a method that can verify that certain classes of Datalog rules are not sound for the R-GCN. In our experiments, we train R-GCNs on KG completion benchmarks, and we are able to verify that no Datalog rule is sound for these models, even though the models often obtain high to near-perfect accuracy. This raises some concerns about the ability of R-GCN models to generalise and about the explainability of their predictions. We further provide two variations to the training paradigm of R-GCN that encourage it to learn sound rules and find a trade-off between model accuracy and the number of learned sound rules., Comment: Full version (with appendices) of paper accepted to KR 2024 (21st International Conference on Principles of Knowledge Representation and Reasoning)
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- 2024
3. First Measurement of Solar $^8$B Neutrinos via Coherent Elastic Neutrino-Nucleus Scattering with XENONnT
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Aprile, E., Aalbers, J., Abe, K., Maouloud, S. Ahmed, Althueser, L., Andrieu, B., Angelino, E., Martin, D. Antón, Arneodo, F., Baudis, L., Bazyk, M., Bellagamba, L., Biondi, R., Bismark, A., Boese, K., Brown, A., Bruno, G., Budnik, R., Cai, C., Capelli, C., Cardoso, J. M. R., Chávez, A. P. Cimental, Colijn, A. P., Conrad, J., Cuenca-García, J. J., D'Andrea, V., Garcia, L. C. Daniel, Decowski, M. P., Deisting, A., Di Donato, C., Di Gangi, P., Diglio, S., Eitel, K., Elykov, A., Ferella, A. D., Ferrari, C., Fischer, H., Flehmke, T., Flierman, M., Fulgione, W., Fuselli, C., Gaemers, P., Gaior, R., Galloway, M., Gao, F., Ghosh, S., Giacomobono, R., Glade-Beucke, R., Grandi, L., Grigat, J., Guan, H., Guida, M., Gyorgy, P., Hammann, R., Higuera, A., Hils, C., Hoetzsch, L., Hood, N. F., Iacovacci, M., Itow, Y., Jakob, J., Joerg, F., Kaminaga, Y., Kara, M., Kavrigin, P., Kazama, S., Kobayashi, M., Koke, D., Kopec, A., Kuger, F., Landsman, H., Lang, R. F., Levinson, L., Li, I., Li, S., Liang, S., Lin, Y. -T., Lindemann, S., Lindner, M., Liu, K., Liu, M., Loizeau, J., Lombardi, F., Long, J., Lopes, J. A. M., Luce, T., Ma, Y., Macolino, C., Mahlstedt, J., Mancuso, A., Manenti, L., Marignetti, F., Undagoitia, T. Marrodán, Martens, K., Masbou, J., Masson, E., Mastroianni, S., Melchiorre, A., Merz, J., Messina, M., Michael, A., Miuchi, K., Molinario, A., Moriyama, S., Morå, K., Mosbacher, Y., Murra, M., Müller, J., Ni, K., Oberlack, U., Paetsch, B., Pan, Y., Pellegrini, Q., Peres, R., Peters, C., Pienaar, J., Pierre, M., Plante, G., Pollmann, T. R., Principe, L., Qi, J., Qin, J., García, D. Ramírez, Rajado, M., Singh, R., Sanchez, L., Santos, J. M. F. dos, Sarnoff, I., Sartorelli, G., Schreiner, J., Schulte, P., Eißing, H. Schulze, Schumann, M., Lavina, L. Scotto, Selvi, M., Semeria, F., Shagin, P., Shi, S., Shi, J., Silva, M., Simgen, H., Takeda, A., Tan, P. -L., Thers, D., Toschi, F., Trinchero, G., Tunnell, C. D., Tönnies, F., Valerius, K., Vecchi, S., Vetter, S., Solar, F. I. Villazon, Volta, G., Weinheimer, C., Weiss, M., Wenz, D., Wittweg, C., Wu, V. H. S., Xing, Y., Xu, D., Xu, Z., Yamashita, M., Yang, L., Ye, J., Yuan, L., Zavattini, G., and Zhong, M.
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Nuclear Experiment ,Astrophysics - Solar and Stellar Astrophysics ,High Energy Physics - Experiment ,Physics - Instrumentation and Detectors - Abstract
We present the first measurement of nuclear recoils from solar $^8$B neutrinos via coherent elastic neutrino-nucleus scattering with the XENONnT dark matter experiment. The central detector of XENONnT is a low-background, two-phase time projection chamber with a 5.9\,t sensitive liquid xenon target. A blind analysis with an exposure of 3.51\,t$\times$y resulted in 37 observed events above 0.5\,keV, with ($26.4^{+1.4}_{-1.3}$) events expected from backgrounds. The background-only hypothesis is rejected with a statistical significance of 2.73\,$\sigma$. The measured $^8$B solar neutrino flux of $(4.7_{-2.3}^{+3.6})\times 10^6\,\mathrm{cm}^{-2}\mathrm{s}^{-1}$ is consistent with results from dedicated solar neutrino experiments. The measured neutrino flux-weighted CE$\nu$NS cross-section on Xe of $(1.1^{+0.8}_{-0.5})\times10^{-39}\,\mathrm{cm}^2$ is consistent with the Standard Model prediction. This is the first direct measurement of nuclear recoils from solar neutrinos with a dark matter detector.
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- 2024
4. Optimizing Charge Transport Simulation for Deep Learning Enhanced Spatial Resolution of the M\'ONCH Detector
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Xie, X., Barten, R., Bergamaschi, A., Braham, B., Brückner, M., Carulla, M., Dinapoli, R., Ebner, S., Ferjaoui, K., Fröjdh, E., Greiffenberg, D., Hasanaj, S., Heymes, J., Hinger, V., King, T., Kozlowski, P., Lopez-Cuenca, C., Mezza, D., Moustakas, K., Mozzanica, A., Paton, K. A., Ruder, C., Schmitt, B., Sieberer, P., Thattil, D., and Zhang, J.
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Physics - Instrumentation and Detectors - Abstract
Deep learning has the potential to significantly enhance the spatial resolution of hybrid detectors for electrons, as demonstrated for electron microscopy using 200 keV electrons with the M\"ONCH 25 {\mu}m pitch charge integration pixel detector. The deep learning models have been trained using both simulation data, which are more straightforward to generate with varied parameters, and measurement data, which are more cumbersome to acquire due to the required specialized setup of the electron microscope. However, challenges arise when comparing simulation-based deep learning models to measurement-based models for electrons, as the spatial resolution achieved through simulations is notably inferior to that from measurements. Discrepancies are also observed when directly comparing X-ray simulations with measurements, particularly in the spectral output of single pixels. These observations collectively suggest that current simulations require optimization. To address this, a Monte Carlo simulation was conducted to model the dynamics of charge carriers within the silicon sensor, aiming to refine charge transport modeling. The simulation encompasses the initial generation of the charge cloud, charge cloud drift, charge diffusion and repulsion, and electronic noise. The simulation results were validated with measurements from the M\"ONCH detector for X-rays, and consistencies between the simulation and the measurements were significantly improved by accounting for the charge repulsion., Comment: Prepared for submission to JINST as a proceeding for 25th International Workshops on Radiation Imaging Detectors
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- 2024
5. Entropy and Spectrum of Near-Extremal Black Holes: semiclassical brane solutions to non-perturbative problems
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Hernández-Cuenca, Sergio
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High Energy Physics - Theory ,General Relativity and Quantum Cosmology ,Quantum Physics - Abstract
The black hole entropy has been observed to generically turn negative at exponentially low temperatures $T\sim e^{-S_0}$ in the extremal Bekenstein-Hawking entropy $S_0$, a seeming pathology often attributed to missing non-perturbative effects. In fact, we show that this negativity must happen for any effective theory of quantum gravity with an ensemble description. To do so, we identify the usual gravitational entropy as an annealed entropy $S_a$, and prove that this quantity gives $S_0$ at extremality if and only if the ground-state energy is protected by supersymmetry, and diverges negatively otherwise. The actual thermodynamically-behaved quantity is the average or quenched entropy $S_q$, whose calculation is poorly understood in gravity: it involves replica wormholes in a regime where the topological expansion breaks down. Using matrix integrals we find new instanton saddles that dominate gravitational correlators at $T\sim e^{-S_0}$ and are dual to semiclassical wormholes involving dynamical branes. These brane solutions give the leading contribution to any black hole very near extremality, and a duality with matrix ensembles would not make sense without them. In the non-BPS case, they are required to make $S_q$ non-negative and also enhance the negativity of $S_a$, both effects consistent with matrix integrals evaluated exactly. Our instanton results are tested against the on-shell action of D3-branes dual to multiply wrapped Wilson loops in $\mathcal{N}=4$ super-YM, and a precise match is found. Our analysis of low-energy random matrix spectra also explains the origin of spectral gaps in supersymmetric theories, not only when there are BPS states at zero energy, but also for purely non-BPS supermultiplets. In the former, our prediction for the gap in terms of the degeneracy of BPS states agrees with the R-charge scaling in gapped multiplets of $\mathcal{N}=2$ super-JT gravity., Comment: 67+33 pages, 14 figures
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- 2024
6. The Symplectic Schur Process
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Cuenca, Cesar and Mucciconi, Matteo
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Mathematical Physics ,Mathematics - Combinatorics ,Mathematics - Probability ,05E05, 60K35, 82B23, 05A19 - Abstract
We define a measure on tuples of partitions, called the symplectic Schur process, that should be regarded as the right analogue of the Schur process of Okounkov-Reshetikhin for the Cartan type C. The weights of our measure include factors that are universal symplectic characters, as well as a novel family of "Down-Up Schur functions" that we define and for which we prove new identities of Cauchy-Littlewood-type. Our main structural result is that the point process corresponding to the symplectic Schur process is determinantal and we find an explicit correlation kernel. We also present dynamics that preserve the family of symplectic Schur processes and explore an alternative sampling scheme, based on the Berele insertion algorithm, in a special case. Finally, we study the asymptotics of the Berele insertion process and find explicit formulas for the limit shape and fluctuations near the bulk and the edge. One of the limit regimes leads to a new kernel that resembles the symmetric Pearcey kernel., Comment: 58 pages, 5 figures
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- 2024
7. Core-hole Coherent Spectroscopy in Molecules
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Rodríguez-Cuenca, Emilio, Picón, Antonio, Oberli, Solène, Kuleff, Alexander I., and Vendrell, Oriol
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Physics - Optics ,Physics - Chemical Physics - Abstract
We study the ultrafast dynamics initiated by a coherent superposition of core-excited states of nitrous oxide molecule. Using high-level \textit{ab-initio} methods, we show that the decoherence caused by the electronic decay and the nuclear dynamics is substantially slower than the induced ultrafast quantum beatings, allowing the system to undergo several oscillations before it dephases. We propose a proof-of-concept experiment using the harmonic up-conversion scheme available at X-ray free-electron laser facilities to trace the evolution of the created core-excited-state coherence through a time-resolved X-ray photoelectron spectroscopy.
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- 2024
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8. XENONnT WIMP Search: Signal & Background Modeling and Statistical Inference
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XENON Collaboration, Aprile, E., Aalbers, J., Abe, K., Maouloud, S. Ahmed, Althueser, L., Andrieu, B., Angelino, E., Martin, D. Antón, Arneodo, F., Baudis, L., Bazyk, M., Bellagamba, L., Biondi, R., Bismark, A., Boese, K., Brown, A., Bruno, G., Budnik, R., Cardoso, J. M. R., Chávez, A. P. Cimental, Colijn, A. P., Conrad, J., Cuenca-García, J. J., D'Andrea, V., Garcia, L. C. Daniel, Decowski, M. P., Di Donato, C., Di Gangi, P., Diglio, S., Eitel, K., Elykov, A., Ferella, A. D., Ferrari, C., Fischer, H., Flehmke, T., Flierman, M., Fulgione, W., Fuselli, C., Gaemers, P., Gaior, R., Galloway, M., Gao, F., Ghosh, S., Giacomobono, R., Glade-Beucke, R., Grandi, L., Grigat, J., Guan, H., Guida, M., Gyoergy, P., Hammann, R., Higuera, A., Hils, C., Hoetzsch, L., Hood, N. F., Iacovacci, M., Itow, Y., Jakob, J., Joerg, F., Kaminaga, Y., Kara, M., Kavrigin, P., Kazama, S., Kobayashi, M., Kopec, A., Kuger, F., Landsman, H., Lang, R. F., Levinson, L., Li, I., Li, S., Liang, S., Lin, Y. -T., Lindemann, S., Lindner, M., Liu, K., Loizeau, J., Lombardi, F., Long, J., Lopes, J. A. M., Luce, T., Ma, Y., Macolino, C., Mahlstedt, J., Mancuso, A., Manenti, L., Marignetti, F., Undagoitia, T. Marrodán, Martens, K., Masbou, J., Masson, E., Mastroianni, S., Melchiorre, A., Messina, M., Michael, A., Miuchi, K., Molinario, A., Moriyama, S., Morå, K., Mosbacher, Y., Murra, M., Müller, J., Ni, K., Oberlack, U., Paetsch, B., Pan, Y., Pellegrini, Q., Peres, R., Peters, C., Pienaar, J., Pierre, M., Plante, G., Pollmann, T. R., Principe, L., Qi, J., Qin, J., García, D. Ramírez, Rajado, M., Singh, R., Sanchez, L., Santos, J. M. F. dos, Sarnoff, I., Sartorelli, G., Schreiner, J., Schulte, D., Schulte, P., Eißing, H. Schulze, Schumann, M., Lavina, L. Scotto, Selvi, M., Semeria, F., Shagin, P., Shi, S., Shi, J., Silva, M., Simgen, H., Takeda, A., Tan, P. -L., Terliuk, A., Thers, D., Toschi, F., Trinchero, G., Tunnell, C. D., Tönnies, F., Valerius, K., Vecchi, S., Vetter, S., Solar, F. I. Villazon, Volta, G., Weinheimer, C., Weiss, M., Wenz, D., Wittweg, C., Wu, V. H. S., Xing, Y., Xu, D., Xu, Z., Yamashita, M., Yang, L., Ye, J., Yuan, L., Zavattini, G., and Zhong, M.
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Physics - Data Analysis, Statistics and Probability ,Astrophysics - Instrumentation and Methods for Astrophysics ,High Energy Physics - Experiment ,Physics - Instrumentation and Detectors - Abstract
The XENONnT experiment searches for weakly-interacting massive particle (WIMP) dark matter scattering off a xenon nucleus. In particular, XENONnT uses a dual-phase time projection chamber with a 5.9-tonne liquid xenon target, detecting both scintillation and ionization signals to reconstruct the energy, position, and type of recoil. A blind search for nuclear recoil WIMPs with an exposure of 1.1 tonne-years yielded no signal excess over background expectations, from which competitive exclusion limits were derived on WIMP-nucleon elastic scatter cross sections, for WIMP masses ranging from 6 GeV/$c^2$ up to the TeV/$c^2$ scale. This work details the modeling and statistical methods employed in this search. By means of calibration data, we model the detector response, which is then used to derive background and signal models. The construction and validation of these models is discussed, alongside additional purely data-driven backgrounds. We also describe the statistical inference framework, including the definition of the likelihood function and the construction of confidence intervals., Comment: 20 pages, 10 figures
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- 2024
9. Operad of posets 101: The Wixarika posets
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Arciniega-Nevárez, José Antonio, Berghoff, Marko, and Dolores-Cuenca, Eric Rubiel
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Mathematics - Combinatorics ,18M80, 06A07, 00-01, 05A15 - Abstract
We study objects whose definition is linked to partial orders. An algebra over the operad of posets is a set whose endomorphisms contain the endomorphisms of posets. Notable examples of such algebras include the zeta values, order polytopes, and shuffle series. The language of operads provides us with tools to better understand the combinatorics of these objects. In these notes we describe a non-trivial example of a suboperad ``The Wixarika posets'', alongside its associated algebras. This example is rich enough to showcase the particularities of the field, without delving into technicalities. An old version of these notes were used to give a minicourse in Govt. College University Lahore in Pakistan 2022, and at the BIRS-CMO workshop ``6th meeting of the Mexican Mathematicians in the World'' 2024., Comment: 10 pages, used to give a minicourse in Govt. College University Lahore in Pakistan 2022, and at the BIRS-CMO workshop "6th meeting of the Mexican Mathematicians in the World'' 2024
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- 2024
10. Wormholes and Factorization in Exact Effective Theory
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Hernández-Cuenca, Sergio
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High Energy Physics - Theory ,General Relativity and Quantum Cosmology ,Quantum Physics - Abstract
We study the general framework of effective theories obtained via exact path integration of a complete theory over some sector of its degrees of freedom. Theories constructed this way contain multi-integrals which couple fields arbitrarily far apart, and in certain settings even on path-disconnected components of the space. These are not just entanglement, but genuine non-local interactions that we dub quantum wormholes. Any state the path integral of such an effective theory prepares is shown to be a partial trace of a state of the complete theory over the integrated-out sector. The resulting reduced density operator is generally mixed due to bra-ket wormholes. An infinite family of ensembles of pure states of the complete theory giving the same effective state is identified. These allow one to equivalently interpret any effective state as being prepared by an ensemble of theories. When computing entropic quantities, bra-ket wormholes give rise to replica wormholes. This causes replica path integrals for the effective theory to not factorize even when the underlying manifold does, as expected from mixing. In contrast, effective theories obtained by derivative expansions have no quantum wormholes and prepare pure states. There exist operators in the algebra of effective theories which can distinguish mixed from pure states, implying a breakdown of non-exact effective theories for sufficiently complex observables. This framework unifies and provides new insights into much of the phenomena observed in quantum gravity, including the interplay between wormholes and unitarity, the breakdown of bulk effective theory, the factorization puzzle, state ensembles, theory ensembles, quantum error correction, and baby universes. Some interesting lessons are drawn accounting also for characteristic aspects of gravity concerning IR/UV mixing and Kaluza-Klein reductions., Comment: 67 pages, 10 figures; v2: minor edits, references added
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- 2024
11. Inquiry at Its Core: A Content Analysis of Inquiry Design Models
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Kathryn L. Roberts, Kristy A. Brugar, and Alexander Cuenca
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This article describes a content analysis of 37 Inquiry Design Modules (https://c3teachers.org), conducted with the purpose of identifying the core teaching practices (CTP) necessary to successfully enact them. Although there has been research identifying CTP in other content areas, research on social studies inquiry at the elementary level is an area that has received little attention. In this study, we identify 16 CTP, each of which is observable, teachable, and replicable. Six of these CTP (facilitating discussion; guiding, reinforcing, or directing thinking; asking questions; introducing and defining vocabulary; curating resources; and using graphic organizers or specific tools) occurred with high frequency in the data set and are discussed in depth. Implications for preservice teacher education are discussed.
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- 2024
- Full Text
- View/download PDF
12. Developing an Adaptive Virtual Learning Environment for Sustainable Learning in Individuals with Down Syndrome
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Cristina Arranz-Barcenilla, Sara Pavía, María Consuelo Sáiz Manzanares, Lourdes Alameda Cuenca-Romero, and Sara Gutiérrez-González
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Purpose: The purpose of the paper is to describe the development and implementation of a specialized Virtual Learning Environment (VLE) designed to enhance the knowledge and skills related to sustainability in students with Down Syndrome. This VLE serves as a means to make sustainable concepts more accessible and comprehensible to this specific student group, with the aim of promoting their engagement and understanding of sustainability, environmental awareness, recycling, and sustainable construction. The ultimate goal is to empower students with Down syndrome by providing them with a tailored educational tool that facilitates their learning in a manner that is engaging and effective. Design/methodology/approach: The approach outlines the overarching plan for creating the e-learning platform, including the technological choices and design considerations necessary to make it effective and accessible for students with Down Syndrome. It's a fundamental component of the methodology, as it sets the direction for the platform's development and aligns with the objectives of the study. And also encompass the strategy for teaching and learning sustainability aspects to students with Down syndrome. Findings: Positive Feedback from Tutors and Professionals: The feedback from tutors and professionals is generally positive, with 91.4% finding the platform to be well-organized and 88.6% considering the content adequate and understandable. This suggests that the VLE met the needs and expectations of educators and professionals involved in the learning process. Utility for Professional Practice: Approximately 80% of tutors and professionals found the platform useful for their professional practice, indicating that it has practical applications beyond student learning. This information highlights the success and potential impact of the VLE for this specific target group. Research limitations/implications: The study may not have explored the depth of sustainability concepts covered within the VLE. Future research could delve into the specifics of the content and its effectiveness in teaching complex sustainability topics. Practical implications: The incorporation of universal design principles in the VLE development could serve as a model for creating inclusive e-learning platforms. This has broader implications for improving digital accessibility in education. The positive feedback from tutors and professionals suggests the importance of interdisciplinary collaboration in education. Professionals from various fields, including special education and sustainability, can work together to create effective and inclusive learning tools. Social implications: This study can contribute to the broader discussion on inclusive education and the effective use of technology to enhance learning experiences for individuals with disabilities. Originality/value: The study addresses a crucial gap in the field of sustainability education by focusing on students with Down syndrome. It highlights the importance of making sustainability education inclusive and accessible to a diverse range of learners, including those with disabilities. This originality contributes to the broader discourse on inclusive education and environmental awareness. The development of a specialized Virtual Learning Environment (VLE) for this specific target group is an original contribution. It demonstrates the potential for adapting educational technology to meet the unique needs of students with Down syndrome, potentially serving as a model for future educational tool development.
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- 2024
- Full Text
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13. Global Point Cloud Registration Network for Large Transformations
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Cuevas-Velasquez, Hanz, Galán-Cuenca, Alejandro, Gallego, Antonio Javier, Saval-Calvo, Marcelo, and Fisher, Robert B.
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Computer Science - Computer Vision and Pattern Recognition - Abstract
Three-dimensional data registration is an established yet challenging problem that is key in many different applications, such as mapping the environment for autonomous vehicles, and modeling objects and people for avatar creation, among many others. Registration refers to the process of mapping multiple data into the same coordinate system by means of matching correspondences and transformation estimation. Novel proposals exploit the benefits of deep learning architectures for this purpose, as they learn the best features for the data, providing better matches and hence results. However, the state of the art is usually focused on cases of relatively small transformations, although in certain applications and in a real and practical environment, large transformations are very common. In this paper, we present ReLaTo (Registration for Large Transformations), an architecture that faces the cases where large transformations happen while maintaining good performance for local transformations. This proposal uses a novel Softmax pooling layer to find correspondences in a bilateral consensus manner between two point sets, sampling the most confident matches. These matches are used to estimate a coarse and global registration using weighted Singular Value Decomposition (SVD). A target-guided denoising step is then applied to both the obtained matches and latent features, estimating the final fine registration considering the local geometry. All these steps are carried out following an end-to-end approach, which has been shown to improve 10 state-of-the-art registration methods in two datasets commonly used for this task (ModelNet40 and KITTI), especially in the case of large transformations.
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- 2024
14. Offline tagging of radon-induced backgrounds in XENON1T and applicability to other liquid xenon detectors
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Aprile, E., Aalbers, J., Abe, K., Maouloud, S. Ahmed, Althueser, L., Andrieu, B., Angelino, E., Angevaare, J. R., Martin, D. Antón, Arneodo, F., Baudis, L., Baxter, A. L., Bazyk, M., Bellagamba, L., Biondi, R., Bismark, A., Brookes, E. J., Brown, A., Bruno, G., Budnik, R., Bui, T. K., Cardoso, J. M. R., Chavez, A. P. Cimental, Colijn, A. P., Conrad, J., Cuenca-García, J. J., D'Andrea, V., Garcia, L. C. Daniel, Decowski, M. P., Di Donato, C., Di Gangi, P., Diglio, S., Eitel, K., Elykov, A., Ferella, A. D., Ferrari, C., Fischer, H., Flehmke, T., Flierman, M., Fulgione, W., Fuselli, C., Gaemers, P., Gaior, R., Galloway, M., Gao, F., Ghosh, S., Glade-Beucke, R., Grandi, L., Grigat, J., Guan, H., Guida, M., Hammann, R., Higuera, A., Hils, C., Hoetzsch, L., Hood, N. F., Iacovacci, M., Itow, Y., Jakob, J., Joerg, F., Joy, A., Kaminaga, Y., Kara, M., Kavrigin, P., Kazama, S., Kobayashi, M., Kopec, A., Kuger, F., Landsman, H., Lang, R. F., Levinson, L., Li, I., Li, S., Liang, S., Lin, Y. T., Lindemann, S., Lindner, M., Liu, K., Loizeau, J., Lombardi, F., Long, J., Lopes, J. A. M., Luce, T., Ma, Y., Macolino, C., Mahlstedt, J., Mancuso, A., Manenti, L., Marignetti, F., Undagoitia, T. Marrodán, Martens, K., Masbou, J., Masson, E., Mastroianni, S., Melchiorre, A., Messina, M., Michael, A., Miuchi, K., Molinario, A., Moriyama, S., Morå, K., Mosbacher, Y., Murra, M., Müller, J., Ni, K., Oberlack, U., Paetsch, B., Palacio, J., Pan, Y., Pellegrini, Q., Peres, R., Peters, C., Pienaar, J., Pierre, M., Plante, G., Pollmann, T. R., Principe, L., Qi, J., Qin, J., García, D. Ramírez, Rajado, M., Shi, J., Singh, R., Sanchez, L., Santos, J. M. F. dos, Sarnoff, I., Sartorelli, G., Schreiner, J., Schulte, D., Schulte, P., Eißing, H. Schulze, Schumann, M., Lavina, L. Scotto, Selvi, M., Semeria, F., Shagin, P., Shi, S., Silva, M., Simgen, H., Takeda, A., Tan, P. -L., Terliuk, A., Thers, D., Toschi, F., Trinchero, G., Tunnell, C., Tönnies, F., Valerius, K., Vecchi, S., Vetter, S., Volta, G., Weinheimer, C., Weiss, M., Wenz, D., Wittweg, C., Wolf, T., Wu, V. H. S., Xing, Y., Xu, D., Xu, Z., Yamashita, M., Yang, L., Ye, J., Yuan, L., Zavattini, G., Zhong, M., and Zhu, T.
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High Energy Physics - Experiment ,Physics - Instrumentation and Detectors - Abstract
This paper details the first application of a software tagging algorithm to reduce radon-induced backgrounds in liquid noble element time projection chambers, such as XENON1T and XENONnT. The convection velocity field in XENON1T was mapped out using $^{222}\text{Rn}$ and $^{218}\text{Po}$ events, and the root-mean-square convection speed was measured to be $0.30 \pm 0.01$ cm/s. Given this velocity field, $^{214}\text{Pb}$ background events can be tagged when they are followed by $^{214}\text{Bi}$ and $^{214}\text{Po}$ decays, or preceded by $^{218}\text{Po}$ decays. This was achieved by evolving a point cloud in the direction of a measured convection velocity field, and searching for $^{214}\text{Bi}$ and $^{214}\text{Po}$ decays or $^{218}\text{Po}$ decays within a volume defined by the point cloud. In XENON1T, this tagging system achieved a $^{214}\text{Pb}$ background reduction of $6.2^{+0.4}_{-0.9}\%$ with an exposure loss of $1.8\pm 0.2 \%$, despite the timescales of convection being smaller than the relevant decay times. We show that the performance can be improved in XENONnT, and that the performance of such a software-tagging approach can be expected to be further improved in a diffusion-limited scenario. Finally, a similar method might be useful to tag the cosmogenic $^{137}\text{Xe}$ background, which is relevant to the search for neutrinoless double-beta decay., Comment: 17 pages, 19 figures
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- 2024
15. The XENONnT Dark Matter Experiment
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XENON Collaboration, Aprile, E., Aalbers, J., Abe, K., Maouloud, S. Ahmed, Althueser, L., Andrieu, B., Angelino, E., Angevaare, J. R., Antochi, V. C., Martin, D. Antón, Arneodo, F., Balata, M., Baudis, L., Baxter, A. L., Bazyk, M., Bellagamba, L., Biondi, R., Bismark, A., Brookes, E. J., Brown, A., Bruenner, S., Bruno, G., Budnik, R., Bui, T. K., Cai, C., Cardoso, J. M. R., Cassese, F., Chiarini, A., Cichon, D., Chavez, A. P. Cimental, Colijn, A. P., Conrad, J., Corrieri, R., Cuenca-García, J. J., Cussonneau, J. P., Dadoun, O., D'Andrea, V., Decowski, M. P., De Fazio, B., Di Gangi, P., Diglio, S., Disdier, J. M., Douillet, D., Eitel, K., Elykov, A., Farrell, S., Ferella, A. D., Ferrari, C., Fischer, H., Flierman, M., Form, S., Front, D., Fulgione, W., Fuselli, C., Gaemers, P., Gaior, R., Rosso, A. Gallo, Galloway, M., Gao, F., Gardner, R., Garroum, N., Glade-Beucke, R., Grandi, L., Grigat, J., Guan, H., Guerzoni, M., Guida, M., Hammann, R., Higuera, A., Hils, C., Hoetzsch, L., Hood, N. F., Howlett, J., Huhmann, C., Iacovacci, M., Iaquaniello, G., Iven, L., Itow, Y., Jakob, J., Joerg, F., Joy, A., Kara, M., Kavrigin, P., Kazama, S., Kobayashi, M., Koltman, G., Kopec, A., Kuger, F., Landsman, H., Lang, R. F., Levinson, L., Li, I., Li, S., Liang, S., Lindemann, S., Lindner, M., Liu, K., Loizeau, J., Lombardi, F., Long, J., Lopes, J. A. M., Ma, Y., Macolino, C., Mahlstedt, J., Mancuso, A., Manenti, L., Marignetti, F., Undagoitia, T. Marrodán, Martella, P., Martens, K., Masbou, J., Masson, D., Masson, E., Mastroianni, S., Mele, E., Messina, M., Michinelli, R., Miuchi, K., Molinario, A., Moriyama, S., Morå, K., Mosbacher, Y., Murra, M., Müller, J., Ni, K., Nisi, S., Oberlack, U., Orlandi, D., Othegraven, R., Paetsch, B., Palacio, J., Parlati, S., Paschos, P., Pellegrini, Q., Peres, R., Peters, C., Pienaar, J., Pierre, M., Plante, G., Pollmann, T. R., Qi, J., Qin, J., García, D. Ramírez, Rynge, M., Shi, J., Singh, R., Sanchez, L., Santos, J. M. F. dos, Sarnoff, I., Sartorelli, G., Schreiner, J., Schulte, D., Schulte, P., Eißing, H. Schulze, Schumann, M., Lavina, L. Scotto, Selvi, M., Semeria, F., Shagin, P., Shi, S., Shockley, E., Silva, M., Simgen, H., Stephen, J., Stern, M., Stillwell, B. K., Takeda, A., Tan, P. -L., Tatananni, D., Terliuk, A., Thers, D., Toschi, F., Trinchero, G., Tunnell, C., Tönnies, F., Valerius, K., Volta, G., Weinheimer, C., Weiss, M., Wenz, D., Westermann, J., Wittweg, C., Wolf, T., Wu, V. H. S., Xing, Y., Xu, D., Xu, Z., Yamashita, M., Yang, L., Ye, J., Yuan, L., Zavattini, G., Zhong, M., and Zhu, T.
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Physics - Instrumentation and Detectors ,Astrophysics - Instrumentation and Methods for Astrophysics ,High Energy Physics - Experiment - Abstract
The multi-staged XENON program at INFN Laboratori Nazionali del Gran Sasso aims to detect dark matter with two-phase liquid xenon time projection chambers of increasing size and sensitivity. The XENONnT experiment is the latest detector in the program, planned to be an upgrade of its predecessor XENON1T. It features an active target of 5.9 tonnes of cryogenic liquid xenon (8.5 tonnes total mass in cryostat). The experiment is expected to extend the sensitivity to WIMP dark matter by more than an order of magnitude compared to XENON1T, thanks to the larger active mass and the significantly reduced background, improved by novel systems such as a radon removal plant and a neutron veto. This article describes the XENONnT experiment and its sub-systems in detail and reports on the detector performance during the first science run., Comment: 32 pages, 19 figures
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- 2024
16. Robust stability analysis of an energy-efficient control in a Networked Control System with application to Unmanned Ground Vehicles
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Gonzalez, Antonio, Cuenca, Angel, Salt, Julian, and Jacobs, Jelle
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Electrical Engineering and Systems Science - Systems and Control ,Mathematics - Optimization and Control - Abstract
In this paper, the robust stability and disturbance rejection performance analysis of an energy-efficient control is addressed in the framework of Networked Control System (NCS). The control scheme under study integrates periodic event-triggered control, packet-based control, time-varying Kalman filter, dual-rate control and prediction techniques, whose design is aimed at reducing energy consumption and bandwidth usage. The robust stability against time-varying model uncertainties is analyzed by means of a suficient condition based on Linear Matrix Inequalities (LMI). Finally, the effectiveness of the proposed approach is experimentally validated in a tracking control for an Unmanned Ground Vehicle (UGV), which is a battery-constrained mobile device with limited computation capacities., Comment: 38 pages, 12 figures, Information Sciences, 2021
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- 2024
17. Delay-independent dual-rate PID controller for a packetbased Networked Control System
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Alcaina, J., Cuenca, A., Salt, J., Casanovaa, V., and Pizá, R.
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Mathematics - Optimization and Control - Abstract
In this paper, a novel delay-independent control structure for a networked control system (NCS) is proposed, where packet-based control strategies with predictor-based and dual-rate control techniques are integrated. The control solution is able to cope with some networked communication problems such as time-varying delays, packet dropouts and packet disorder. In addition, the proposed approach enables to reduce network load, and usage of connected devices, while maintaining a satisfactory control performance. As a delayindependent control solution, no network-induced delay measurement is needed for controller implementation. In addition, the control scheme is applicable to open-loop unstable plants. Control system stability is ensured in terms of linear matrix inequalities (LMIs). Simulation results show the main benefits of the control approach, which are experimentally validated by means of a Cartesian-robot-based test-bed platform., Comment: 39 pages, 9 figures
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- 2024
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18. Practical Reasoning in DatalogMTL
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Wang, Dingmin, Wałęga, Przemysław A., Hu, Pan, and Grau, Bernardo Cuenca
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Computer Science - Logic in Computer Science - Abstract
DatalogMTL is an extension of Datalog with metric temporal operators that has found an increasing number of applications in recent years. Reasoning in DatalogMTL is, however, of high computational complexity, which makes reasoning in modern data-intensive applications challenging. In this paper we present a practical reasoning algorithm for the full DatalogMTL language, which we have implemented in a system called MeTeoR. Our approach effectively combines an optimised (but generally non-terminating) materialisation (a.k.a. forward chaining) procedure, which provides scalable behaviour, with an automata-based component that guarantees termination and completeness. To ensure favourable scalability of the materialisation component, we propose a novel semina\"ive materialisation procedure for DatalogMTL enjoying the non-repetition property, which ensures that each specific rule application will be considered at most once throughout the entire execution of the algorithm. Moreover, our materialisation procedure is enhanced with additional optimisations which further reduce the number of redundant computations performed during materialisation by disregarding rules as soon as it is certain that they cannot derive new facts in subsequent materialisation steps. Our extensive evaluation supports the practicality of our approach., Comment: Under consideration in Theory and Practice of Logic Programming (TPLP). arXiv admin note: text overlap with arXiv:2208.07100
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- 2024
19. Barriers and Strategies to Optimize the Use of Glucagon-Like Peptide 1 Receptor Agonists in People with Type 2 Diabetes and High Cardiovascular Risk or Established Cardiovascular Disease: A Delphi Consensus in Spain
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Botana López, Manuel, Camafort Babkowski, Miguel, Campuzano Ruiz, Raquel, Cebrián Cuenca, Ana, Gargallo Fernández, Manuel, David de Paz, Héctor, Redondo-Antón, Jennifer, Artime, Esther, Díaz-Cerezo, Silvia, and Rubio de Santos, Miriam
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- 2024
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20. Shell Tools and Use-Wear Analysis: a Reference Collection for Prehistoric Arabia
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Lidour, Kevin and Cuenca Solana, David
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- 2024
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21. Improving change of direction in male football players through plyometric training: a systematic review
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Jimenez-Iglesias, Jose, Owen, Adam L., Cruz-Leon, Carolina, Campos-Vázquez, Miguel Angel, Sanchez-Parente, Sandra, Gonzalo-Skok, Oliver, Cuenca-Garcia, Magdalena, and Castro-Piñero, Jose
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- 2024
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22. A novel flaw detection approach in carbon steel pipes through ultrasonic guided waves and optimized transformer neural networks
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Flores Cuenca, Manuel Fernando, Malikov, Azamatjon Kakhramon ugli, Kim, Jeongnam, Cho, Younho, and Jeong, Kyoung-sik
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- 2024
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23. Insights into the Window of Opportunity and Outcome Measures in Patients with Moderate to Severe Hidradenitis Suppurativa Treated with Secukinumab: A Real-World Study
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Haselgruber, Sofía, Fernández-Crehuet-Serrano, Pablo, Fernández-Ballesteros, María Dolores, Padial-Gómez, Alicia, Hernández-Rodríguez, Juan Carlos, Ortiz-Álvarez, Juan, Navarro-Guillamón, Pedro, Membrive-Jiménez, Cristina, Cuenca-Barrales, Carlos, and Molina-Leyva, Alejandro
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- 2024
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24. A chromosome-level genome assembly for the smoky rubyspot damselfly (Hetaerina titia)
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Patterson, Christophe W, Bonillas-Monge, Erandi, Brennan, Adrian, Grether, Gregory F, Mendoza-Cuenca, Luis, Tucker, Rachel, Vega-Sánchez, Yesenia M, and Drury, Jonathan
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Biological Sciences ,Genetics ,Animals ,Female ,Odonata ,Smoke ,Biological Evolution ,Pigmentation ,Chromosomes ,aquatic insect ,Calopterygidae ,comparative genomics ,long-read sequencing ,Omni-C ,PacBio ,riparian ,Zygoptera ,Evolutionary Biology ,Evolutionary biology - Abstract
Smoky rubyspot damselflies (Hetaerina titia Drury, 1773) are one of the most commonly encountered odonates along streams and rivers on both slopes of Central America and the Atlantic drainages in the United States and southern Canada. Owing to their highly variable wing pigmentation, they have become a model system for studying sexual selection and interspecific behavioral interference. Here, we sequence and assemble the genome of a female smoky rubyspot. Of the primary assembly (i.e. the principle pseudohaplotype), 98.8% is made up of 12 chromosomal pseudomolecules (2N = 22A + X). There are 75 scaffolds in total, an N50 of 120 Mb, a contig-N50 of 0.64 Mb, and a high arthropod BUSCO score [C: 97.6% (S: 97.3%, D: 0.3%), F: 0.8%, M: 1.6%]. We then compare our assembly to that of the blue-tailed damselfly genome (Ischnura elegans), the most complete damselfly assembly to date, and a recently published assembly for an American rubyspot damselfly (Hetaerina americana). Collectively, these resources make Hetaerina a genome-enabled genus for further studies of the ecological and evolutionary forces shaping biological diversity.
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- 2024
25. Population genomics of post-glacial western Eurasia
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Allentoft, Morten E, Sikora, Martin, Refoyo-Martínez, Alba, Irving-Pease, Evan K, Fischer, Anders, Barrie, William, Ingason, Andrés, Stenderup, Jesper, Sjögren, Karl-Göran, Pearson, Alice, Sousa da Mota, Bárbara, Schulz Paulsson, Bettina, Halgren, Alma, Macleod, Ruairidh, Jørkov, Marie Louise Schjellerup, Demeter, Fabrice, Sørensen, Lasse, Nielsen, Poul Otto, Henriksen, Rasmus A, Vimala, Tharsika, McColl, Hugh, Margaryan, Ashot, Ilardo, Melissa, Vaughn, Andrew, Fischer Mortensen, Morten, Nielsen, Anne Birgitte, Ulfeldt Hede, Mikkel, Johannsen, Niels Nørkjær, Rasmussen, Peter, Vinner, Lasse, Renaud, Gabriel, Stern, Aaron, Jensen, Theis Zetner Trolle, Scorrano, Gabriele, Schroeder, Hannes, Lysdahl, Per, Ramsøe, Abigail Daisy, Skorobogatov, Andrei, Schork, Andrew Joseph, Rosengren, Anders, Ruter, Anthony, Outram, Alan, Timoshenko, Aleksey A, Buzhilova, Alexandra, Coppa, Alfredo, Zubova, Alisa, Silva, Ana Maria, Hansen, Anders J, Gromov, Andrey, Logvin, Andrey, Gotfredsen, Anne Birgitte, Henning Nielsen, Bjarne, González-Rabanal, Borja, Lalueza-Fox, Carles, McKenzie, Catriona J, Gaunitz, Charleen, Blasco, Concepción, Liesau, Corina, Martinez-Labarga, Cristina, Pozdnyakov, Dmitri V, Cuenca-Solana, David, Lordkipanidze, David O, En’shin, Dmitri, Salazar-García, Domingo C, Price, T Douglas, Borić, Dušan, Kostyleva, Elena, Veselovskaya, Elizaveta V, Usmanova, Emma R, Cappellini, Enrico, Brinch Petersen, Erik, Kannegaard, Esben, Radina, Francesca, Eylem Yediay, Fulya, Duday, Henri, Gutiérrez-Zugasti, Igor, Merts, Ilya, Potekhina, Inna, Shevnina, Irina, Altinkaya, Isin, Guilaine, Jean, Hansen, Jesper, Aura Tortosa, Joan Emili, Zilhão, João, Vega, Jorge, Buck Pedersen, Kristoffer, Tunia, Krzysztof, Zhao, Lei, Mylnikova, Liudmila N, Larsson, Lars, Metz, Laure, Yepiskoposyan, Levon, Pedersen, Lisbeth, Sarti, Lucia, Orlando, Ludovic, Slimak, Ludovic, Klassen, Lutz, Blank, Malou, González-Morales, Manuel, and Silvestrini, Mara
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Biological Sciences ,Genetics ,History ,Heritage and Archaeology ,Human Society ,Historical Studies ,Anthropology ,Biotechnology ,Humans ,Genomics ,Diploidy ,Agriculture ,Europe ,Metagenomics ,General Science & Technology - Abstract
Western Eurasia witnessed several large-scale human migrations during the Holocene1-5. Here, to investigate the cross-continental effects of these migrations, we shotgun-sequenced 317 genomes-mainly from the Mesolithic and Neolithic periods-from across northern and western Eurasia. These were imputed alongside published data to obtain diploid genotypes from more than 1,600 ancient humans. Our analyses revealed a 'great divide' genomic boundary extending from the Black Sea to the Baltic. Mesolithic hunter-gatherers were highly genetically differentiated east and west of this zone, and the effect of the neolithization was equally disparate. Large-scale ancestry shifts occurred in the west as farming was introduced, including near-total replacement of hunter-gatherers in many areas, whereas no substantial ancestry shifts happened east of the zone during the same period. Similarly, relatedness decreased in the west from the Neolithic transition onwards, whereas, east of the Urals, relatedness remained high until around 4,000 BP, consistent with the persistence of localized groups of hunter-gatherers. The boundary dissolved when Yamnaya-related ancestry spread across western Eurasia around 5,000 BP, resulting in a second major turnover that reached most parts of Europe within a 1,000-year span. The genetic origin and fate of the Yamnaya have remained elusive, but we show that hunter-gatherers from the Middle Don region contributed ancestry to them. Yamnaya groups later admixed with individuals associated with the Globular Amphora culture before expanding into Europe. Similar turnovers occurred in western Siberia, where we report new genomic data from a 'Neolithic steppe' cline spanning the Siberian forest steppe to Lake Baikal. These prehistoric migrations had profound and lasting effects on the genetic diversity of Eurasian populations.
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- 2024
26. The XENONnT dark matter experiment.
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Aprile, E, Aalbers, J, Abe, K, Ahmed Maouloud, S, Althueser, L, Andrieu, B, Angelino, E, Angevaare, J, Antochi, V, Antón Martin, D, Arneodo, F, Balata, M, Baudis, L, Baxter, A, Bazyk, M, Bellagamba, L, Biondi, R, Bismark, A, Brookes, E, Brown, A, Bruenner, S, Bruno, G, Budnik, R, Bui, T, Cai, C, Cardoso, J, Cassese, F, Chiarini, A, Cichon, D, Cimental Chavez, A, Colijn, A, Conrad, J, Corrieri, R, Cuenca-García, J, Cussonneau, J, Dadoun, O, DAndrea, V, Decowski, M, De Fazio, B, Gangi, P, Diglio, S, Disdier, J, Douillet, D, Eitel, K, Elykov, A, Farrell, S, Ferella, A, Ferrari, C, Fischer, H, Flierman, M, Form, S, Front, D, Fulgione, W, Fuselli, C, Gaemers, P, Gaior, R, Rosso, A, Galloway, M, Gao, F, Gardner, R, Garroum, N, Glade-Beucke, R, Grandi, L, Grigat, J, Guan, H, Guerzoni, M, Guida, M, Hammann, R, Higuera, A, Hils, C, Hoetzsch, L, Hood, N, Howlett, J, Huhmann, C, Iacovacci, M, Iaquaniello, G, Iven, L, Itow, Y, Jakob, J, Joerg, F, Joy, A, Kara, M, Kavrigin, P, Kazama, S, Kobayashi, M, Koltman, G, Kopec, A, Kuger, F, Landsman, H, Lang, R, Levinson, L, Li, I, Li, S, Liang, S, Lindemann, S, Lindner, M, Liu, K, Loizeau, J, Lombardi, F, and Long, J
- Abstract
The multi-staged XENON program at INFN Laboratori Nazionali del Gran Sasso aims to detect dark matter with two-phase liquid xenon time projection chambers of increasing size and sensitivity. The XENONnT experiment is the latest detector in the program, planned to be an upgrade of its predecessor XENON1T. It features an active target of 5.9 tonnes of cryogenic liquid xenon (8.5 tonnes total mass in cryostat). The experiment is expected to extend the sensitivity to WIMP dark matter by more than an order of magnitude compared to XENON1T, thanks to the larger active mass and the significantly reduced background, improved by novel systems such as a radon removal plant and a neutron veto. This article describes the XENONnT experiment and its sub-systems in detail and reports on the detector performance during the first science run.
- Published
- 2024
27. Beyond the Holographic Entropy Cone via Cycle Flows
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He, Temple, Hernández-Cuenca, Sergio, and Keeler, Cynthia
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High Energy Physics - Theory ,Mathematics - Combinatorics ,Quantum Physics - Abstract
Motivated by bit threads, we introduce a new prescription for computing entropy vectors outside the holographic entropy cone. By utilizing cycle flows on directed graphs, we show that the maximum cycle flow associated to any subset of vertices, which corresponds to a subsystem, manifestly obeys purification symmetry. Furthermore, by restricting ourselves to a subclass of directed graphs, we prove that the maximum cycle flow obeys both subadditivity and strong subadditivity, thereby establishing it as a viable candidate for the entropy associated to the subsystem. Finally, we demonstrate how our model generalizes the entropy vectors obtainable via conventional flows in undirected graphs, as well as conjecture that our model similarly generalizes the entropy vectors arising from hypergraphs., Comment: 30 pages, 9 figures; v2: Significant change to Theorem 1, specified to networks satisfying a nesting property which we characterize by necessary and sufficient conditions, demoted Proposition 4 to Conjecture 1, minor typos and clarifications added, references added
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- 2023
28. Shuffle series
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Ahmad, Khushdil, Dolores-Cuenca, Eric Rubiel, and Shabbir, Khurram
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Mathematics - Combinatorics ,Mathematics - Algebraic Topology ,05A15 (Primary) 18M80, 05A10, 06A11 - Abstract
We apply operad theory to enumerative combinatorics in order to count the number of shuffles between series-parallel posets and chains. We work with three types of shuffles, two of them noncommutative, for example a local deck-divider shuffle $A$ between $P$ and $Q$ is a shuffle of the posets in which, on every maximal chain $m\subset A$, the minimum and maximum elements belong to $P$ and no two consecutive points of $Q$ appear consecutively on $m$. The number of local deck-divider shuffles of $P$ and $Q$ differ from the number of local deck-divider shuffles of $Q$ and $P$. The generating functions whose $n$ coefficient counts shuffles between a poset $P$ and $1<2<\cdots
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- 2023
29. Characterization of iLGADs using soft X-rays
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Liguori, Antonio, Barten, Rebecca, Baruffaldi, Filippo, Bergamaschi, Anna, Borghi, Giacomo, Boscardin, Maurizio, Brückner, Martin, Butcher, Tim Alexander, Carulla, Maria, Vignali, Matteo Centis, Dinapoli, Roberto, Ebner, Simon, Ficorella, Francesco, Fröjdh, Erik, Greiffenberg, Dominic, Ali, Omar Hammad, Hasanaj, Shqipe, Heymes, Julian, Hinger, Viktoria, King, Thomas, Kozlowski, Pawel, Lopez-Cuenca, Carlos, Mezza, Davide, Moustakas, Konstantinos, Mozzanica, Aldo, Paternoster, Giovanni, Paton, Kirsty A., Ronchin, Sabina, Ruder, Christian, Schmitt, Bernd, Thattil, Dhanya, Xie, Xiangyu, and Zhang, Jiaguo
- Subjects
Physics - Instrumentation and Detectors - Abstract
Experiments at synchrotron radiation sources and X-ray Free-Electron Lasers in the soft X-ray energy range ($250$eV--$2$keV) stand to benefit from the adaptation of the hybrid silicon detector technology for low energy photons. Inverse Low Gain Avalanche Diode (iLGAD) sensors provide an internal gain, enhancing the signal-to-noise ratio and allowing single photon detection below $1$keV using hybrid detectors. In addition, an optimization of the entrance window of these sensors enhances their quantum efficiency (QE). In this work, the QE and the gain of a batch of different iLGAD diodes with optimized entrance windows were characterized using soft X-rays at the Surface/Interface:Microscopy beamline of the Swiss Light Source synchrotron. Above $250$eV, the QE is larger than $55\%$ for all sensor variations, while the charge collection efficiency is close to $100\%$. The average gain depends on the gain layer design of the iLGADs and increases with photon energy. A fitting procedure is introduced to extract the multiplication factor as a function of the absorption depth of X-ray photons inside the sensors. In particular, the multiplication factors for electron- and hole-triggered avalanches are estimated, corresponding to photon absorption beyond or before the gain layer, respectively., Comment: 16 pages, 8 figures
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- 2023
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30. Knowledge, Attitudes, and Perceived Ethics Regarding the Use of ChatGPT among Generation Z University Students
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Benicio Gonzalo Acosta-Enriquez, Marco Agustín Arbulú Ballesteros, Carmen Graciela Arbulu Perez Vargas, Milca Naara Orellana Ulloa, Cristian Raymound Gutiérrez Ulloa, Johanna Micaela Pizarro Romero, Néstor Daniel Gutiérrez Jaramillo, Héctor Ulises Cuenca Orellana, Diego Xavier Ayala Anzoátegui, and Carlos López Roca
- Abstract
Artificial intelligence (AI) has been integrated into higher education (HE), offering numerous benefits and transforming teaching and learning. Since its launch, ChatGPT has become the most popular learning model among Generation Z college students in HE. This study aimed to assess the knowledge, concerns, attitudes, and ethics of using ChatGPT among Generation Z college students in HE in Peru. An online survey was administered to 201 HE students with prior experience using the ChatGPT for academic activities. Two of the six proposed hypotheses were confirmed: Perceived Ethics (B = 0.856) and Student Concerns (B = 0.802). The findings suggest that HE students' knowledge and positive attitudes toward ChatGPT do not guarantee its effective adoption and use. It is important to investigate how attitudes of optimism, skepticism, or apathy toward AI develop and how these attitudes influence the intention to use technologies such as the ChatGPT in HE settings. The dependence on ChatGPT raises ethical concerns that must be addressed with responsible use programs in HE. No sex or age differences were found in the relationship between the use of ChatGPTs and perceived ethics among HE students. However, further studies with diverse HE samples are needed to determine this relationship. To promote the ethical use of the ChatGPT in HE, institutions must develop comprehensive training programs, guidelines, and policies that address issues such as academic integrity, privacy, and misinformation. These initiatives should aim to educate students and university teachers on the responsible use of ChatGPT and other AI-based tools, fostering a culture of ethical adoption of AI to leverage its benefits and mitigate its potential risks, such as a lack of academic integrity.
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- 2024
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31. A novel method of ultrasonic tomographic imaging of defects in the coating layer by image fusion and binarization techniques
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Cuenca, Manuel Fernando Flores, Malikov, Azamatjon Kakhramon ugli, Kim, Jeongnam, Kim, Young H., and Cho, Younho
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- 2024
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32. An unbiased ranking of murine dietary models based on their proximity to human metabolic dysfunction-associated steatotic liver disease (MASLD)
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Vacca, Michele, Kamzolas, Ioannis, Harder, Lea Mørch, Oakley, Fiona, Trautwein, Christian, Hatting, Maximilian, Ross, Trenton, Bernardo, Barbara, Oldenburger, Anouk, Hjuler, Sara Toftegaard, Ksiazek, Iwona, Lindén, Daniel, Schuppan, Detlef, Rodriguez-Cuenca, Sergio, Tonini, Maria Manuela, Castañeda, Tamara R., Kannt, Aimo, Rodrigues, Cecília M. P., Cockell, Simon, Govaere, Olivier, Daly, Ann K., Allison, Michael, Honnens de Lichtenberg, Kristian, Kim, Yong Ook, Lindblom, Anna, Oldham, Stephanie, Andréasson, Anne-Christine, Schlerman, Franklin, Marioneaux, Jonathon, Sanyal, Arun, Afonso, Marta B., Younes, Ramy, Amano, Yuichiro, Friedman, Scott L., Wang, Shuang, Bhattacharya, Dipankar, Simon, Eric, Paradis, Valérie, Burt, Alastair, Grypari, Ioanna Maria, Davies, Susan, Driessen, Ann, Yashiro, Hiroaki, Pors, Susanne, Worm Andersen, Maja, Feigh, Michael, Yunis, Carla, Bedossa, Pierre, Stewart, Michelle, Cater, Heather L., Wells, Sara, Schattenberg, Jörn M., Anstee, Quentin M., Tiniakos, Dina, Perfield, James W., Petsalaki, Evangelia, Davidsen, Peter, and Vidal-Puig, Antonio
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- 2024
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33. One sixth of Amazonian tree diversity is dependent on river floodplains
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Householder, John Ethan, Wittmann, Florian, Schöngart, Jochen, Piedade, Maria Teresa Fernandez, Junk, Wolfgang J., Latrubesse, Edgardo Manuel, Quaresma, Adriano Costa, Demarchi, Layon O., de S. Lobo, Guilherme, Aguiar, Daniel P. P. de, Assis, Rafael L., Lopes, Aline, Parolin, Pia, Leão do Amaral, Iêda, Coelho, Luiz de Souza, de Almeida Matos, Francisca Dionízia, Lima Filho, Diógenes de Andrade, Salomão, Rafael P., Castilho, Carolina V., Guevara-Andino, Juan Ernesto, Carim, Marcelo de Jesus Veiga, Phillips, Oliver L., Cárdenas López, Dairon, Magnusson, William E., Sabatier, Daniel, Revilla, Juan David Cardenas, Molino, Jean-François, Irume, Mariana Victória, Martins, Maria Pires, Guimarães, José Renan da Silva, Ramos, José Ferreira, Rodrigues, Domingos de Jesus, Bánki, Olaf S., Peres, Carlos A., Pitman, Nigel C. A., Hawes, Joseph E., Almeida, Everton José, Barbosa, Luciane Ferreira, Cavalheiro, Larissa, dos Santos, Márcia Cléia Vilela, Luize, Bruno Garcia, Novo, Evlyn Márcia Moraes de Leão, Núñez Vargas, Percy, Silva, Thiago Sanna Freire, Venticinque, Eduardo Martins, Manzatto, Angelo Gilberto, Reis, Neidiane Farias Costa, Terborgh, John, Casula, Katia Regina, Costa, Flávia R. C., Honorio Coronado, Euridice N., Monteagudo Mendoza, Abel, Montero, Juan Carlos, Feldpausch, Ted R., Aymard C, Gerardo A., Baraloto, Chris, Castaño Arboleda, Nicolás, Engel, Julien, Petronelli, Pascal, Zartman, Charles Eugene, Killeen, Timothy J., Rincón, Lorena Maniguaje, Marimon, Beatriz S., Marimon-Junior, Ben Hur, Schietti, Juliana, Sousa, Thaiane R., Vasquez, Rodolfo, Mostacedo, Bonifacio, Dantas do Amaral, Dário, Castellanos, Hernán, Medeiros, Marcelo Brilhante de, Simon, Marcelo Fragomeni, Andrade, Ana, Camargo, José Luís, Laurance, William F., Laurance, Susan G. W., Farias, Emanuelle de Sousa, Lopes, Maria Aparecida, Magalhães, José Leonardo Lima, Mendonça Nascimento, Henrique Eduardo, Queiroz, Helder Lima de, Brienen, Roel, Stevenson, Pablo R., Araujo-Murakami, Alejandro, Baker, Tim R., Cintra, Bruno Barçante Ladvocat, Feitosa, Yuri Oliveira, Mogollón, Hugo F., Noronha, Janaína Costa, Barbosa, Flávia Rodrigues, de Sá Carpanedo, Rainiellen, Duivenvoorden, Joost F., Silman, Miles R., Ferreira, Leandro Valle, Levis, Carolina, Lozada, José Rafael, Comiskey, James A., Draper, Freddie C., Toledo, José Julio de, Damasco, Gabriel, Dávila, Nállarett, García-Villacorta, Roosevelt, Vicentini, Alberto, Cornejo Valverde, Fernando, Alonso, Alfonso, Arroyo, Luzmila, Dallmeier, Francisco, Gomes, Vitor H. F., Jimenez, Eliana M., Neill, David, Peñuela Mora, Maria Cristina, Carvalho, Fernanda Antunes, Coelho de Souza, Fernanda, Feeley, Kenneth J., Gribel, Rogerio, Pansonato, Marcelo Petratti, Ríos Paredes, Marcos, Barlow, Jos, Berenguer, Erika, Dexter, Kyle G., Ferreira, Joice, Fine, Paul V. A., Guedes, Marcelino Carneiro, Huamantupa-Chuquimaco, Isau, Licona, Juan Carlos, Pennington, Toby, Villa Zegarra, Boris Eduardo, Vos, Vincent Antoine, Cerón, Carlos, Fonty, Émile, Henkel, Terry W., Maas, Paul, Pos, Edwin, Silveira, Marcos, Stropp, Juliana, Thomas, Raquel, Daly, Doug, Milliken, William, Pardo Molina, Guido, Vieira, Ima Célia Guimarães, Albuquerque, Bianca Weiss, Campelo, Wegliane, Emilio, Thaise, Fuentes, Alfredo, Klitgaard, Bente, Marcelo Pena, José Luis, Souza, Priscila F., Tello, J. Sebastián, Vriesendorp, Corine, Chave, Jerome, Di Fiore, Anthony, Hilário, Renato Richard, Pereira, Luciana de Oliveira, Phillips, Juan Fernando, Rivas-Torres, Gonzalo, van Andel, Tinde R., von Hildebrand, Patricio, Balee, William, Barbosa, Edelcilio Marques, Bonates, Luiz Carlos de Matos, Doza, Hilda Paulette Dávila, Gómez, Ricardo Zárate, Gonzales, Therany, Gonzales, George Pepe Gallardo, Hoffman, Bruce, Junqueira, André Braga, Malhi, Yadvinder, Miranda, Ires Paula de Andrade, Mozombite-Pinto, Linder Felipe, Prieto, Adriana, Rudas, Agustín, Ruschel, Ademir R., Silva, Natalino, Vela, César I. A., Zent, Stanford, Zent, Egleé L., Cano, Angela, Carrero Márquez, Yrma Andreina, Correa, Diego F., Costa, Janaina Barbosa Pedrosa, Flores, Bernardo Monteiro, Galbraith, David, Holmgren, Milena, Kalamandeen, Michelle, Nascimento, Marcelo Trindade, Oliveira, Alexandre A., Ramirez-Angulo, Hirma, Rocha, Maira, Scudeller, Veridiana Vizoni, Sierra, Rodrigo, Tirado, Milton, Umaña, Maria Natalia, van der Heijden, Geertje, Vilanova Torre, Emilio, Ahuite Reategui, Manuel Augusto, Baider, Cláudia, Balslev, Henrik, Cárdenas, Sasha, Casas, Luisa Fernanda, Farfan-Rios, William, Ferreira, Cid, Linares-Palomino, Reynaldo, Mendoza, Casimiro, Mesones, Italo, Parada, Germaine Alexander, Torres-Lezama, Armando, Urrego Giraldo, Ligia Estela, Villarroel, Daniel, Zagt, Roderick, Alexiades, Miguel N., de Oliveira, Edmar Almeida, Garcia-Cabrera, Karina, Hernandez, Lionel, Palacios Cuenca, Walter, Pansini, Susamar, Pauletto, Daniela, Ramirez Arevalo, Freddy, Sampaio, Adeilza Felipe, Valderrama Sandoval, Elvis H., Valenzuela Gamarra, Luis, and ter Steege, Hans
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- 2024
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34. Safety and Effectiveness of Percutaneous Ultrasound-Guided Galvanic Current in Tunnels of Patients with Hidradenitis Suppurativa: A Pilot Study
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Soto-Moreno, Alberto, Cuenca-Barrales, Carlos, Arias-Santiago, Salvador, García-Vidal, José Antonio, Medina-Mirapeix, Francesc, and Molina-Leyva, Alejandro
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- 2024
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35. Immunohistochemical, functional, and anatomical evaluation of patients with idiopathic epiretinal membrane
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Martín, Julio Cesar Molina, Sánchez, Laura Fernández, Piñero, David P., and Navarro, Nicolás Cuenca
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- 2024
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36. Gestational immune activation disrupts hypothalamic neurocircuits of maternal care behavior
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Zambon, Alice, Rico, Laura Cuenca, Herman, Mathieu, Gundacker, Anna, Telalovic, Amina, Hartenberger, Lisa-Marie, Kuehn, Rebekka, Romanov, Roman A., Hussaini, S. Abid, Harkany, Tibor, and Pollak, Daniela D.
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- 2024
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37. Invasive Fungal Diseases in Adult Patients in Intensive Care Unit (FUNDICU): 2024 consensus definitions from ESGCIP, EFISG, ESICM, ECMM, MSGERC, ISAC, and ISHAM
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Bassetti, Matteo, Giacobbe, Daniele R., Agvald-Ohman, Christina, Akova, Murat, Alastruey-Izquierdo, Ana, Arikan-Akdagli, Sevtap, Azoulay, Elie, Blot, Stijn, Cornely, Oliver A., Cuenca-Estrella, Manuel, de Lange, Dylan W., De Rosa, Francesco G., De Waele, Jan J., Dimopoulos, George, Garnacho-Montero, Jose, Hoenigl, Martin, Kanj, Souha S., Koehler, Philipp, Kullberg, Bart J., Lamoth, Frédéric, Lass-Flörl, Cornelia, Maertens, Johan, Martin-Loeches, Ignacio, Muñoz, Patricia, Poulakou, Garyphallia, Rello, Jordi, Sanguinetti, Maurizio, Taccone, Fabio S., Timsit, Jean-François, Torres, Antoni, Vazquez, Jose A., Wauters, Joost, Asperges, Erika, Cortegiani, Andrea, Grecchi, Cecilia, Karaiskos, Ilias, Le Bihan, Clément, Mercier, Toine, Mortensen, Klaus L., Peghin, Maddalena, Rebuffi, Chiara, Tejada, Sofia, Vena, Antonio, Zuccaro, Valentina, Scudeller, Luigia, and Calandra, Thierry
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- 2024
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38. Optimization of a Horizontal Washing Machine Suspension System: Studying a 7 DOF Dynamic Model Using a Genetic Algorithm Through a Bounding Box Fitness Function
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Mendoza-Flores, Shair, Velázquez-Villegas, Fernando, and Cuenca-Jiménez, Francisco
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- 2024
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39. Colorectal procedures with the novel Hugo™ RAS system: training process and case series report from a non-robotic surgical team
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Romero-Marcos, Juan-Manuel, Sampson-Dávila, Jaime-Gerardo, Cuenca-Gómez, Carlota, Altet-Torné, Juan, González-Abós, Sandra, Ojeda-Jiménez, Iris, Galaviz-Sosa, María-Luisa, and Delgado-Rivilla, Salvadora
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- 2024
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40. Design and performance of the field cage for the XENONnT experiment
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Aprile, E., Abe, K., Maouloud, S. Ahmed, Althueser, L., Andrieu, B., Angelino, E., Angevaare, J. R., Antochi, V. C., Martin, D. Antón, Arneodo, F., Baudis, L., Baxter, A. L., Bazyk, M., Bellagamba, L., Biondi, R., Bismark, A., Brookes, E. J., Brown, A., Bruenner, S., Bruno, G., Budnik, R., Bui, T. K., Cai, C., Cardoso, J. M. R., Cichon, D., Chávez, A. P. Cimental, Colijn, A. P., Conrad, J., Cuenca-García, J. J., Cussonneau, J. P., DÁndrea, V., Decowski, M. P., Di Gangi, P., Diglio, S., Eitel, K., Elykov, A., Farrell, S., Ferella, A. D., Ferrari, C., Fischer, H., Flierman, M., Fulgione, W., Fuselli, C., Gaemers, P., Gaior, R., Rosso, A. Gallo, Galloway, M., Gao, F., Glade-Beucke, R., Grandi, L., Grigat, J., Guan, H., Guida, M., Hammann, R., Higuera, A., Hils, C., Hoetzsch, L., Hood, N. F., Howlett, J., Iacovacci, M., Itow, Y., Jakob, J., Joerg, F., Joy, A., Kara, M., Kavrigin, P., Kazama, S., Kobayashi, M., Koltman, G., Kopec, A., Kuger, F., Landsman, H., Lang, R. F., Levinson, L., Li, I., Li, S., Liang, S., Lindemann, S., Lindner, M., Liu, K., Loizeau, J., Lombardi, F., Long, J., Lopes, J. A. M., Ma, Y., Macolino, C., Mahlstedt, J., Mancuso, A., Manenti, L., Marignetti, F., Undagoitia, T. Marrodán, Martens, K., Masbou, J., Masson, D., Masson, E., Mastroianni, S., Messina, M., Miuchi, K., Molinario, A., Moriyama, S., Morå, K., Mosbacher, Y., Murra, M., Müller, J., Ni, K., Oberlack, U., Paetsch, B., Palacio, J., Pellegrini, Q., Peres, R., Peters, C., Pienaar, J., Pierre, M., Plante, G., Pollmann, T. R., Qi, J., Qin, J., García, D. Ramírez, Šarčević, N., Shi, J., Singh, R., Sanchez, L., Santos, J. M. F. dos, Sarnoff, I., Sartorelli, G., Schreiner, J., Schulte, D., Schulte, P., Eißing, H. Schulze, Schumann, M., Lavina, L. Scotto, Selvi, M., Semeria, F., Shagin, P., Shi, S., Shockley, E., Silva, M., Simgen, H., Takeda, A., Tan, P. -L., Terliuk, A., Thers, D., Toschi, F., Trinchero, G., Tunnell, C., Tönnies, F., Valerius, K., Volta, G., Weinheimer, C., Weiss, M., Wenz, D., Wittweg, C., Wolf, T., Wu, V. H. S., Xing, Y., Xu, D., Xu, Z., Yamashita, M., Yang, L., Ye, J., Yuan, L., Zavattini, G., Zhong, M., and Zhu, T.
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High Energy Physics - Experiment ,Physics - Instrumentation and Detectors - Abstract
The precision in reconstructing events detected in a dual-phase time projection chamber depends on an homogeneous and well understood electric field within the liquid target. In the XENONnT TPC the field homogeneity is achieved through a double-array field cage, consisting of two nested arrays of field shaping rings connected by an easily accessible resistor chain. Rather than being connected to the gate electrode, the topmost field shaping ring is independently biased, adding a degree of freedom to tune the electric field during operation. Two-dimensional finite element simulations were used to optimize the field cage, as well as its operation. Simulation results were compared to ${}^{83m}\mathrm{Kr}$ calibration data. This comparison indicates an accumulation of charge on the panels of the TPC which is constant over time, as no evolution of the reconstructed position distribution of events is observed. The simulated electric field was then used to correct the charge signal for the field dependence of the charge yield. This correction resolves the inconsistent measurement of the drift electron lifetime when using different calibrations sources and different field cage tuning voltages.
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- 2023
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41. Holographic Entropy Inequalities and Multipartite Entanglement
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Hernández-Cuenca, Sergio, Hubeny, Veronika E., and Jia, Frederic
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High Energy Physics - Theory ,Quantum Physics - Abstract
We study holographic entropy inequalities and their structural properties by making use of a judicious grouping of terms into certain multipartite information quantities. This allows us to recast cumbersome entropic expressions into much simpler ones which share interestingly rigid structures. By performing a systematic search over some of these structures, we are able to discover more than 300 novel entropy inequalities for six parties, thereby demonstrating that these recastings provide a fruitful generating technique for uncovering new holographic entropy inequalities. In attempting to interpret the corresponding sign-definite quantities as correlation measures, we also obtain a no-go result: the superbalance property of holographic entropy inequalities turns out to preclude them from being monotonic under partial tracing. In the process, we also comment on the geometrical significance of multipartite information quantities and present various structural relations amongst them., Comment: v1: 40 pages, 384 inequalities. v2: 1877 inequalities (w/ numbering distinct from v1); new tables in App. C; link to living repository added
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- 2023
42. Framework for additive manufacturing of porous Inconel 718 for electrochemical applications
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Zafari, Ahmad, Kiran, Kiran, Gimenez-Garcia, Inmaculada, Forner-Cuenca, Antoni, Xia, Kenong, Gibson, Ian, and Jafari, Davoud
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Condensed Matter - Materials Science ,Physics - Chemical Physics - Abstract
Porous electrodes were developed using laser powder bed fusion of Inconel 718 lattice structures and electrodeposition of a porous nickel catalytic layer. Laser energy densities of ~83-333 J/m were used to fabricate ~500 um thick electrodes made of body centered cubic unit cells of 200-500 um and strut thicknesses of 100-200 um. Unit cells of 500 um and strut thickness of 200 um were identified as optimum. Despite small changes in feature sizes by the energy input, the porosity of >50% and pore size of ~100 um did not change. In a subsequent step, we used nickel electrodeposition to create smaller scale pores on the electrode. The electrochemical performance of the electrodes for hydrogen/oxygen evolution reaction (HER/OER) was evaluated in a three-electrode setup. For HER, a much larger maximum current density of ~ -372 mA/cm2 at a less negative potential of ~-0.4 V vs RHE (potential against reversible hydrogen electrode) was obtained in the nickel-coated samples, as compared to -240 mA/cm2 at ~-0.6 V in the bare one, indicating superior performance of the coated sample. Conversely, OER exhibited minor performance differences upon application of the coating, indicating insignificant dependence of OER to surface composition and available surface.
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- 2023
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43. Exploring the potential of tocopherols: mechanisms of action and perspectives in the prevention and treatment of breast cancer
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Nava-Tapia, Dania A., Román-Justo, Norely Y., Cuenca-Rojo, Antonio, Guerrero-Rivera, Lizeth G., Patrón-Guerrero, Annet, Poblete-Cruz, Ruth I., Zacapala-Gómez, Ana E., Sotelo-Leyva, César, Navarro-Tito, Napoleón, and Mendoza-Catalán, Miguel A.
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- 2024
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44. Few-shot learning for COVID-19 chest X-ray classification with imbalanced data: an inter vs. intra domain study
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Galán-Cuenca, Alejandro, Gallego, Antonio Javier, Saval-Calvo, Marcelo, and Pertusa, Antonio
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- 2024
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45. Cross-cultural adaptation of the FRAIL scale for critically ill patients in Spain.
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Arias-Rivera, Susana, Moro-Tejedor, María, Raurell-Torredà, Marta, Cortés-Puch, Irene, Frutos-Vivar, Fernando, Andreu-Vázquez, Cristina, Sánchez-Sánchez, María, Sánchez-Izquierdo, Raquel, Oteiza-López, Lorena, López-Cuenca, Sonia, Checa-López, Marta, Jareño-Collado, Raquel, López-López, Virginia, Sánchez-Muñoz, Eva, Carrasco Rodríguez-Rey, Luis, Frade-Mera, María, Padilla-Peinado, Rebeca, Huete-García, Alejandro, Lesmes-González Aledo, Amanda, Gordo-Vidal, Federico, Rodríguez-Merino, Ana, Vázquez-Calatayud, Mónica, Vázquez-Grande, Gloria, Mateo, Dolores, and Herrero-Hernández, Raquel
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adults ,critical care ,cross-cultural comparison ,frailty ,nurse ,nursing ,translating ,Adult ,Aged ,Humans ,Cross-Cultural Comparison ,Spain ,Critical Illness ,Pilot Projects ,Cross-Sectional Studies ,Frail Elderly ,Frailty - Abstract
AIM: To translate and culturally adapt the FRAIL scale into Spanish and perform a preliminary test of diagnostic accuracy in patients admitted to intensive care units. DESIGN: Cross-sectional diagnostic study. METHODS: Five intensive care units (ICU) in Spain were participated. Stage 1: Three native Spanish-speaking bilingual translators familiar with the field of critical care translated the scale from English into Spanish. Stage 2: Three native English-speaking bilingual translators familiar with critical care medicine. Stage 3: Authors of the original scale compared the English original and back-translated versions of the scale. Stage 4: Five nurses with more than 5 years of ICU experience and five critical care physicians assessed the comprehension and relevance of each of the items of the Spanish version in 30 patients of 3 different age ranges (65 years). RESULTS: The FRAIL scale was translated and adapted cross-culturally for patients admitted to intensive care units in Spain. The process consisted of four stages: translation, back translation, comparison and pilot test. There was good correspondence between the original scale and the Spanish version in 100% of the items. The participating patients assessed the relevance (content validity) and comprehensibility (face validity) of each of the items of the first Spanish version. The relevance of some of the items scored low when the scale was used in patients younger than 65 years. CONCLUSIONS: We have cross-culturally adapted the FRAIL scale, originally in English, to Spanish for its use in the critical care medical setting in Spanish-speaking countries. IMPLICATIONS FOR PROFESSIONALS: Physicians and nurses can apply the new scale to all patients admitted to the intensive care units. Nursing care can be adapted according to frailty, trying to reduce the side effects of admission to these units for the most fragile patients. REPORTING METHOD: The manuscripts authors have adhered to the EQUATOR guidelines, using the COSMIN reporting guideline for studies on the measurement properties of patient-reported outcome measures. PATIENT OR PUBLIC CONTRIBUTION: In a pilot clinical study, we applied the first version of the FRAIL-Spain scale to intensive care unit (ICU) patients. Five nurses with more than 5 years of ICU experience and five critical care physicians assessed the relevance (content validity) and comprehensibility (face validity) of the five items of the first Spanish version. Relevance was assessed using a 4-point Likert scale ranging from 1 (no relevance) to 4 (high relevance), and comprehensibility was assessed as poor, acceptable or good. Each health professional applied the scale to three patients (total number of patients = 30) of three different age ranges (65 years) and recorded the time of application of the scale to each patient. Although the frailty scales were initially created by geriatricians to be applied to the elders, there is little experience with their application in critically ill patients of any age. Therefore, more information is needed to determine the relevance of using this scale in critical care patients. In this pilot study, we considered that nurses and critical care physicians should evaluate frailty using this adapted scale in adult patients admitted to the Intensive Care Units.
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- 2023
46. Use of Orange Peel ( Citrus X sinensis ) for Obtaining Essential Extract as a Natural Degreaser
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Luis David Balarezo Saltos, María Belén Vinces Obando, Carlos Ricardo Delgado Villafuerte, Fabián Fabricio Peñarrieta Macías, Fernando Ramón Isea León, and Gerardo Jose Cuenca Nevarez
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betaine ,epicarp ,natural extract ,degreaser ,glycerin ,Environmental technology. Sanitary engineering ,TD1-1066 ,Environmental sciences ,GE1-350 - Abstract
The growth of industries encourages the increase of waste, and in turn the implementation of eco-friendly techniques and technologies for the treatment and use of them. The objective of the research was to take advantage of the epicarp of Citrus sinensis (L.) Osbeck to obtain an essential extract and formulate a natural degreaser. A diagnosis was made on the production of organic waste by interviewing a company, resulting that, of the total amount of different fruits processed, half were waste without any type of use the essential extract was obtained with the technique of direct extraction to reflux and its quality was determined by measuring the parameters: pH, total solids, percentage of acidity, relative density, and determination of limonene. The essential extract (100-125-150 mL) and betaine (11-15%) were used as study factors and as substances not harmful to the environment for the formulation of the natural degreaser through a bifactorial design and ADEVA and Tukey test at 5% significance. The pH showed significant differences because of the interaction of essential extract*betaine. The use of 150 ml of orange extract and 15% of betaine (A2B1) obtained a greater detachment of lubricating grease, with a value of 2471 NTU and a pH of 5.46 values that were analyzed by spectrophotometry.
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- 2024
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47. El proceso participativo para la transformación del espacio exterior del CEIP Son Basca: la arquitectura como oportunidad para la infancia
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Mariona Genis Vinyals, Jordi Planelles Salvans, Margalida Batle Siquier, Laura Cuenca Cerdà, and Catalina Pons Beltrán
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arquitectura ,patio escolar ,diseño ,participación infantil ,educación infantil ,diseño colaborativo ,investigación acción participativa ,Architecture ,NA1-9428 - Abstract
La Convención sobre los Derechos del Niño establece la participación infantil como un derecho fundamental. Esto significa que se debe permitir a los niños expresar sus puntos de vista, ser escuchados y que sus intereses sean considerados en las decisiones que tienen un impacto directo en ellos. Este principio es clave en el ámbito de los derechos del niño y la protección de la infancia. La presente investigación se centra en la integración de la infancia en los procesos de análisis y transformación arquitectónica de los espacios que ocupan. En particular, se analiza la transformación del espacio exterior del CEIP Son Basca en Sa Pobla, Mallorca, con el objetivo de fomentar un juego más diversificado, el aprendizaje, la inclusión, la coeducación, el confort ambiental y la naturalización. El estudio propone una metodología que implica la participación de toda la comunidad educativa, incluyendo a los niños, para garantizar una participación real y efectiva en la transformación final del patio. La experiencia se justifica por la necesidad de revisar la configuración tradicional de los patios escolares y por la aparición de nuevas metodologías para el diseño de estos espacios. Estas metodologías reconocen la importancia de la arquitectura en la creación de ambientes integrados, menos fragmentados y propicios para el aprendizaje significativo, e incorporan la participación de la infancia. Además de su objetivo principal de implementar la transformación de manera participativa, el estudio destaca el potencial del proceso de diseño colaborativo del patio para generar aprendizajes en varios niveles educativos del centro. Este enfoque participativo no solo mejora el entorno físico, sino que también contribuye al desarrollo educativo y s ocial de los alumnos.
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- 2024
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48. A novel high-throughput qPCR chip for solving co-infections in RAS farmed rainbow trout
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Juliane Sørensen, Argelia Cuenca, Jacob Günther Schmidt, Simon Brøndgaard Madsen, Tine Moesgaard Iburg, Lone Madsen, and Niccoló Vendramin
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Medicine ,Science - Abstract
Abstract Recirculating aquaculture systems (RAS) have become more attractive due to reduced water consumption and effluent discharge. However, intensification of production increases the risk of introducing pathogens at farming sites. The emergence of uncultivable pathogens and RAS pathobiome diversity shifts the traditional disease paradigm from “one pathogen, one disease” to complex multiple-pathogen disease cases. Piscine orthoreovirus genotype 3 (PRV-3) is an excellent example, as it is capable of inducing anemia and heart pathology resembling heart and skeletal muscle inflammation under experimental conditions, and is associated with increased mortality in association with other pathogens in the field. The aim of this study was to develop a method for detection of multiple pathogens and putative pathogens, as co-infections are common in aquaculture. To do this, in the pilot study, we mapped the pathobiome of RAS-farmed rainbow trout (Oncorhynchus mykiss) (commercial RAS, farm A) using both standard diagnostic methods and metabarcording (16S rRNA) to investigate the gill microbiome. During this study, we observed infections with multiple pathogens, and detected two putative gill pathogens Candidatus Branchiomonas cysticola and Candidatus Piscichlamydia salmonis, both of which have been linked with complex gill disease in Atlantic salmon (Salmo salar). Based on the pilot study, we developed and tested a high throughput qPCR (HT-qPCR) chip targeting 22 viral and bacterial pathogens and putative pathogens, followed by a surveillance of a fish cohort in a commercial RAS farm during production (farm B). Co-infection with PRV-3 and Ca. B. cysticola combined with stress inducing management practices may explain the severe disease outbreak observed (37% mortality). The time course study sets the base for a future screening scheme for disease prediction and addresses limitations of the method when testing environmental DNA/RNA.
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- 2024
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49. Oleaxonchium olearum gen. et sp. nov. (Nematoda, Dorylaimida) associated with an olive grove in the southern Iberian Peninsula, and new insights into the evolutionary relationships within Belondiridae
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Reyes Peña-Santiago, Miriam García-Ruiz, Alba N. Ruiz-Cuenca, and Joaquín Abolafia
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Biology (General) ,QH301-705.5 - Abstract
A new belondirid, dorylaimid taxon, Oleaxonchium olearum gen. et sp. nov., collected from an olive grove in the Andalusia region of Spain, is characterised, including its morphological description, morphometrics, SEM study, and molecular (18S-, 28S-rDNA) analyses. The new genus displays a unique combination of traits that distinguishes it from its closest genera: a rectangular lip region with sclerotized margins when observed in lateral view and visibly hexagonal in face view under SEM; a comparatively long cheilostom with thickened walls at its anterior part; a short isthmus-like section separating both pharyngeal regions; a mono-opistho-ovarian didelphic female genital system without pars refringens vaginae; and a short and rounded tail. The new species is characterised by its 2.44–2.87 mm long body, lip region 7–7.5 µm wide, odontostyle 10–10.5 µm long, neck 723–973 µm long, pharyngeal expansion occupying 63–72% of the total neck length, female anterior genital branch 4–6% of body length, tripartite posterior uterus 1.9–2.6 body diameters long, with a short intermediate section bearing sclerotized elements, vulva (V = 58–61) a transverse slit, caudal region 29–35 µm long (c = 74–89, c’ = 0.9–1.1), and male unknown. As derived from an integrative approach combining morphological and molecular data, the new genus is close to Metaxonchium, the polyphyly of Belondiridae is confirmed, and support is provided in favour of the monophyly of Axonchiinae.
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- 2024
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50. Development of an Index to Evaluate Children’s Risk for Being Instrumentalized in Intimate Partner Violence against Women Contexts
- Author
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José C. Ríos Lechuga, Juan M. Alarcón Cuenca, and Esther Lopez-Zafra
- Subjects
children ,evaluation ,intimate partner violence against women ,risk indicators ,Criminal law and procedure ,K5000-5582 ,Psychology ,BF1-990 - Abstract
Background/Objective: The risk of children being instrumentalized in contexts of gender violence poses a social and health problem that impacts children’s future development. The main purpose of this research is to ascertain which risk indicators should be addressed by security force members when facing an emergency call regarding intimate partner violence in which children are present. This tool could be helpful for evaluating and preventing the risk of future aggression as a means to hurt mothers. Method and Results: In the course of three studies, a set of proposed risk indicators was developed. In Study 1, five interviews and two group discussions with experts working in gender violence cases (n = 18) provided us with information to develop an initial version of a measurement tool, the Index of Children’s Risk of being Instrumentalized (ICRI), for gender violence cases. In Study 2, cognitive debriefing was carried out by professionals (n = 26) to evaluate the suitability of the items. This approach allowed us to obtain valid, content-based evidence. Finally, Study 3 included a pretest study in which security force members (n = 44) evaluate the appropriateness of the ICRI and, if needed, to make any necessary adjustments of the index. The results show that the indicators obtained in this initial approximation could help security forces when reporting cases of gender violence with children at the scene. Conclusions: Further attention to evaluating the risk of children living in intimate partner violence contexts is needed.
- Published
- 2024
- Full Text
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