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282 results on '"Cullinane, Daniel C."'

1. Emergency Department SpO2/FiO2 Ratios Correlate with Mechanical Ventilation and Intensive Care Unit Requirements in COVID-19 Patients

Author

Zhang, Gary, Burla, Michael J., Caesar, Benjamin B., Falank, Carolyne R., Kyros, Peter, Zucco, Victoria C., Strumilowska, Aneta, Cullinane, Daniel C., and Sheppard, Forest

Subjects
COVID-19, SpO2/FiO2 ratio, Emergency Medicine, intensive care unit, mechincal ventilation
Abstract

Background: Patients with coronavirus 2019 (COVID-19) are at high risk for respiratory dysfunction. The pulse oximetry/fraction of inspired oxygen (SpO2/FiO2) ratio is a non-invasive assessment of respiratory dysfunction substituted for the PaO2:FiO2 ratio in Sequential Organ Failure Assessment scoring. We hypothesized that emergency department (ED) SpO2/FiO2 ratios correlate with requirement for mechanical ventilation in COVID-19 patients. Our objective was to identify COVID-19 patients at greatest risk of requiring mechanical ventilation, using SpO2/FiO2 ratios.Methods: We performed a retrospective review of patients admitted with COVID-19 at two hospitals. Highest and lowest SpO2/FiO2 ratios (percent saturation/fraction of inspired O2) were calculated on admission. We performed chi-square, univariate, and multiple regression analysis to evaluate the relationship of admission SpO2/FiO2 ratios with requirement for mechanical ventilation and intensive care unit (ICU) care.Results: A total of 539 patients (46% female; 84% White), with a mean age 67.6 ± 18.6 years, met inclusion criteria. Patients who required mechanical ventilation during their hospital stay were statistically younger in age (P = 0.001), had a higher body mass index (P < .001), and there was a higher percentage of patients who were obese (P = 0.03) and morbidly obese (P < .001). Shortness of breath, cough, and fever were the most common presenting symptoms with a median temperature of 99°F. Average white blood count was higher in patients who required ventilation (P =300 and mechanical ventilation or intensive care unit (ICU) requirement.Conclusion: The ED SpO2/FiO2 ratios correlated with mechanical ventilation and ICU requirements during hospitalization for COVID-19. These results support ED SpO2/FiO2 as a possible triage tool and predictor of hospital resource requirements for patients admitted with COVID-19. Further investigation is warranted.

Published
2024

3. Propensity weighted analysis of chemical venous thromboembolism prophylaxis agents in isolated severe traumatic brain injury: An EAST sponsored multicenter study

Author

Ratnasekera, Asanthi M., Seng, Sirivan S., Kim, Daniel, Ji, Wenyan, Jacovides, Christina L., Kaufman, Elinore J., Sadek, Hannah M., Perea, Lindsey L., Poloni, Christina Monaco, Shnaydman, Ilya, Lee, Alexandra Jeongyoon, Sharp, Victoria, Miciura, Angela, Trevizo, Eric, Rosenthal, Martin G., Lottenberg, Lawrence, Zhao, William, Keininger, Alicia, Hunt, Michele, Cull, John, Balentine, Chassidy, Egodage, Tanya, Mohamed, Aleem T., Kincaid, Michelle, Doris, Stephanie, Cotterman, Robert, Seegert, Sara, Jacobson, Lewis E., Williams, Jamie, Moncrief, Melissa, Palmer, Brandi, Mentzer, Caleb, Tackett, Nichole, Hranjec, Tjasa, Dougherty, Thomas, Morrissey, Shawna, Donatelli-Seyler, Lauren, Rushing, Amy, Tatebe, Leah C., Nevill, Tiffany J., Aboutanos, Michel B., Hamilton, David, Redmond, Diane, Cullinane, Daniel C., Falank, Carolyne, McMellen, Mark, Duran, Chris, Daniels, Jennifer, Ballow, Shana, Schuster, Kevin M., and Ferrada, Paula

Published
2024
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4. To close or not to close? Wound management in emergent colorectal surgery, an EAST multicenter prospective cohort study

Author

Feather, Cristina B., Rehrig, Scott, Allen, Rebecca, Barth, Nadine, Kugler, Emmalee M., Cullinane, Daniel C., Falank, Carolyne R., Bhattacharya, Bishwajit, Maung, Adrian A., Seng, Sirivan, Ratnasekera, Asanthi, Bass, Gary Alan, Butler, Dale, Pascual, Jose L., Srikureja, Daniel, Winicki, Nolan, Lynde, Jennifer, Nowak, Brittany, Azar, Faris, Thompson, Lauren A., Nahmias, Jeffry, Manasa, Morgan, Tesoriero, Ronald, Kumar, Sandhya B., Collom, Morgan, Kincaid, Michelle, Sperwer, Kimberly, Santos, Ariel P., Klune, J. Robert, and Turcotte, Justin

Published
2024
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5. A western trauma association multicenter comparison of mesh versus non-mesh repair of blunt traumatic abdominal wall hernias

Author

Harrell, Kevin N., Grimes, Arthur D., Gill, Harkanwar, Reynolds, Jessica K., Ueland, Walker R., Sciarretta, Jason D., Todd, Samual R., Trust, Marc D., Ngoue, Marielle, Thomas, Bradley W., Ayuso, Sullivan A., LaRiccia, Aimee, Spalding, M. Chance, Collins, Michael J., Collier, Bryan R., Karam, Basil S., de Moya, Marc A., Lieser, Mark J., Chipko, John M., Jr, Haan, James M., Lightwine, Kelly L., Cullinane, Daniel C., Falank, Carolyne R., Phillips, Ryan C., Kemp, Michael T., Alam, Hasan B., Udekwu, Pascal O., Sanin, Gloria D., Hildreth, Amy N., Biffl, Walter L., Schaffer, Kathryn B., Marshall, Gary, Muttalib, Omaer, Nahmias, Jeffry, Shahi, Niti, Moulton, Steven L., and Maxwell, Robert A.

Published
2024
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6. Outcomes after ultramassive transfusion in the modern era: An Eastern Association for the Surgery of Trauma multicenter study.

Author

Matthay, Zachary A, Hellmann, Zane J, Callcut, Rachael A, Matthay, Ellicott C, Nunez-Garcia, Brenda, Duong, William, Nahmias, Jeffry, LaRiccia, Aimee K, Spalding, M Chance, Dalavayi, Satya S, Reynolds, Jessica K, Lesch, Heather, Wong, Yee M, Chipman, Amanda M, Kozar, Rosemary A, Penaloza, Liz, Mukherjee, Kaushik, Taghlabi, Khaled, Guidry, Christopher A, Seng, Sirivan S, Ratnasekera, Asanthi, Motameni, Amirreza, Udekwu, Pascal, Madden, Kathleen, Moore, Sarah A, Kirsch, Jordan, Goddard, Jesse, Haan, James, Lightwine, Kelly, Ontengco, Julianne B, Cullinane, Daniel C, Spitzer, Sarabeth A, Kubasiak, John C, Gish, Joshua, Hazelton, Joshua P, Byskosh, Alexandria Z, Posluszny, Joseph A, Ross, Erin E, Park, John J, Robinson, Brittany, Abel, Mary Kathryn, Fields, Alexander T, Esensten, Jonathan H, Nambiar, Ashok, Moore, Joanne, Hardman, Claire, Terse, Pranaya, Luo-Owen, Xian, Stiles, Anquonette, Pearce, Brenden, Tann, Kimberly, Abdul Jawad, Khaled, Ruiz, Gabriel, and Kornblith, Lucy Z

Subjects
Humans, Thrombocytopenia, Wounds and Injuries, Hemorrhage, Prognosis, Treatment Outcome, Blood Component Transfusion, Resuscitation, Glasgow Coma Scale, Injury Severity Score, Hospital Mortality, Risk Factors, Retrospective Studies, Age Factors, Adult, Middle Aged, Trauma Centers, Female, Male, Hematology, Clinical Research, Physical Injury - Accidents and Adverse Effects, Good Health and Well Being, Trauma, hemorrhagic shock, transfusion medicine, Cardiorespiratory Medicine and Haematology, Clinical Sciences, Nursing, Emergency & Critical Care Medicine
Abstract

BackgroundDespite the widespread institution of modern massive transfusion protocols with balanced blood product ratios, survival for patients with traumatic hemorrhage receiving ultramassive transfusion (UMT) (defined as ≥20 U of packed red blood cells [RBCs]) in 24 hours) remains low and resource consumption remains high. Therefore, we aimed to identify factors associated with mortality in trauma patients receiving UMT in the modern resuscitation era.MethodsAn Eastern Association for the Surgery of Trauma multicenter retrospective study of 461 trauma patients from 17 trauma centers who received ≥20 U of RBCs in 24 hours was performed (2014-2019). Multivariable logistic regression and Classification and Regression Tree analysis were used to identify clinical characteristics associated with mortality.ResultsThe 461 patients were young (median age, 35 years), male (82%), severely injured (median Injury Severity Score, 33), in shock (median shock index, 1.2; base excess, -9), and transfused a median of 29 U of RBCs, 22 U of fresh frozen plasma (FFP), and 24 U of platelets (PLT). Mortality was 46% at 24 hours and 65% at discharge. Transfusion of RBC/FFP ≥1.5:1 or RBC/PLT ≥1.5:1 was significantly associated with mortality, most pronounced for the 18% of patients who received both RBC/PLT and RBC/FFP ≥1.5:1 (odds ratios, 3.11 and 2.81 for mortality at 24 hours and discharge; both p < 0.01). Classification and Regression Tree identified that age older than 50 years, low initial Glasgow Coma Scale, thrombocytopenia, and resuscitative thoracotomy were associated with low likelihood of survival (14-26%), while absence of these factors was associated with the highest survival (71%).ConclusionDespite modern massive transfusion protocols, one half of trauma patients receiving UMT are transfused with either RBC/FFP or RBC/PLT in unbalanced ratios ≥1.5:1, with increased associated mortality. Maintaining focus on balanced ratios during UMT is critical, and consideration of advanced age, poor initial mental status, thrombocytopenia, and resuscitative thoracotomy can aid in prognostication.Level of evidencePrognostic, level III.

Published
2021

7. Anticoagulation therapy in patients with traumatic brain injury: An Eastern Association for the Surgery of Trauma multicenter prospective study

Author

Matsushima, Kazuhide, Leichtle, Stefan W, Wild, Jeffrey, Young, Katelyn, Chang, Grace, Demetriades, Demetrios, Group, EAST ACT-TBI Multicenter Study, Lomangino, Cara Diaz, Massetti, Jennifer, Glass, Nina E, Livingston, David H, O’Bosky, Karen, Chan, Julie L, Cullinane, Daniel C, Rippey, Kelly A, Sharma, Jyoti, Nahmias, Jeffry, Grigorian, Areg, Allen, Steven, Armen, Scott B, Berne, John D, Mederos, Dalier, Pascual, Jose L, Resnick, Shelby, Bholat, Omar, Ostry, Lauren, Garcia, Luis J, Vecchio, Rafael Ramos, Winston, Eleanor S, and Sabour, Andrew F

Subjects
Biomedical and Clinical Sciences, Clinical Sciences, Physical Injury - Accidents and Adverse Effects, Patient Safety, Neurosciences, Traumatic Head and Spine Injury, Clinical Research, Brain Disorders, Traumatic Brain Injury (TBI), Hematology, Injuries and accidents, Adult, Aged, Anticoagulants, Atrial Fibrillation, Brain Injuries, Traumatic, Craniotomy, Disease Progression, Female, Hemorrhage, Humans, Male, Middle Aged, Postoperative Complications, Postoperative Period, Preoperative Period, Prospective Studies, Thromboembolism, Time Factors, Time-to-Treatment, United States, Venous Thromboembolism, EAST ACT-TBI Multicenter Study Group, Surgery, Clinical sciences
Abstract

BackgroundTrauma care providers often face a dilemma regarding anticoagulation therapy initiation in patients with traumatic brain injury owing to the associated risks of traumatic brain injury progression. The aims of this study were the following: (1) to describe the current practice of anticoagulation therapy in traumatic brain injury patients and their outcomes and (2) to identify factors associated with the progression of traumatic brain injury after anticoagulation therapy.MethodsIn this multicenter prospective observational study, we included computed tomography-proven traumatic brain injury patients who received anticoagulation therapy within 30 days of hospital admission. Our primary outcome was the incidence of clinically significant progression of traumatic brain injury after anticoagulation therapy initiation.ResultsA total of 168 patients were enrolled more than 22 months. Atrial fibrillation and venous thromboembolism were the most common pre-injury and postinjury anticoagulation therapy indications, respectively. Overall, 16 patients (9.6%) experienced clinically significant traumatic brain injury progression after anticoagulation therapy, out of which 9 (5.4%) patients subsequently required neurosurgical interventions. Between patients with clinical progression of traumatic brain injury and patients who showed no such progression, there were no significant differences in the baseline demographics and severity of traumatic brain injury. However, anticoagulation therapy was initiated significantly earlier in patients of the deterioration group than those of the no-deterioration group (4.5 days vs 11 days, P = .015). In a multiple logistic regression model, patients who received anticoagulation therapy later after injury had significantly lower risk of clinically significant traumatic brain injury progression (odds ratio: 0.915 for each day, 95% confidence interval: 0.841-0.995, P = .037).ConclusionOur results suggest that early anticoagulation therapy is associated with higher risk of traumatic brain injury progression, thus a balance between bleeding and thromboembolic risks should be carefully evaluated in each case before initiating anticoagulation therapy.

Published
2021

8. Colorectal resection in emergency general surgery: An EAST multicenter trial.

Author

Aicher, Brittany O, Hernandez, Matthew C, Betancourt-Ramirez, Alejandro, Grossman, Michael D, Heise, Holly, Schroeppel, Thomas J, Kongkaewpaisan, Napaporn, Kaafarani, Haytham MA, Wagner, Afton, Grabo, Daniel, Scott, Michael, Peck, Gregory, Chang, Gloria, Matsushima, Kazuhide, Cullinane, Daniel C, Cullinane, Laura M, Stocker, Benjamin, Posluszny, Joseph, Simonoski, Ursula J, Catalano, Richard D, Vasileiou, Georgia, Yeh, D Dante, Agrawal, Vaidehi, Truitt, Michael S, Pickett, MaryAnne, Dultz, Linda, Muller, Alison, Ong, Adrian W, San Roman, Janika L, Barth, Nadine, Fackelmayer, Oliver, Velopulos, Catherine G, Hendrix, Cheralyn, Estroff, Jordan M, Gambhir, Sahil, Nahmias, Jeffry, Jeyamurugan, Kokila, Bugaev, Nikolay, Portillo, Victor, Carrick, Matthew M, O'Meara, Lindsay, Kufera, Joseph, Zielinski, Martin D, and Bruns, Brandon R

Subjects
Biomedical and Clinical Sciences, Clinical Sciences, Cancer, Colo-Rectal Cancer, Digestive Diseases, Patient Safety, Clinical Research, 6.4 Surgery, Evaluation of treatments and therapeutic interventions, Good Health and Well Being, Aged, Anastomosis, Surgical, Colectomy, Colorectal Surgery, Diverticulitis, Colonic, Emergencies, Female, General Surgery, Hospital Mortality, Humans, Logistic Models, Male, Middle Aged, Multivariate Analysis, Postoperative Complications, Practice Patterns, Physicians', Prospective Studies, Treatment Outcome, United States, Emergency general surgery, colon resection, ostomy, colon anastomosis, Clinical sciences, Nursing
Abstract

ObjectiveEvidence comparing stoma creation (STM) versus anastomosis after urgent or emergent colorectal resection is limited. This study examined outcomes after colorectal resection in emergency general surgery patients.MethodsThis was an Eastern Association for the Surgery of Trauma-sponsored prospective observational multicenter study of patients undergoing urgent/emergent colorectal resection. Twenty-one centers enrolled patients for 11 months. Preoperative, intraoperative, and postoperative variables were recorded. χ, Mann-Whitney U test, and multivariable logistic regression models were used to describe outcomes and risk factors for surgical complication/mortality.ResultsA total of 439 patients were enrolled (ANST, 184; STM, 255). The median (interquartile range) age was 62 (53-71) years, and the median Charlson Comorbidity Index (CCI) was 4 (1-6). The most common indication for surgery was diverticulitis (28%). Stoma group was older (64 vs. 58 years, p < 0.001), had a higher CCI, and were more likely to be immunosuppressed. Preoperatively, STM patients were more likely to be intubated (57 vs. 15, p < 0.001), on vasopressors (61 vs. 13, p < 0.001), have pneumoperitoneum (131 vs. 41, p < 0.001) or fecal contamination (114 vs. 33, p < 0.001), and had a higher incidence of elevated lactate (149 vs. 67, p < 0.001). Overall mortality was 13%, which was higher in STM patients (18% vs. 8%, p = 0.02). Surgical complications were more common in STM patients (35% vs. 25%, p = 0.02). On multivariable analysis, management with an open abdomen, intraoperative blood transfusion, and larger hospital size were associated with development of a surgical complication, while CCI, preoperative vasopressor use, steroid use, open abdomen, and intraoperative blood transfusion were independently associated with mortality.ConclusionThis study highlights a tendency to perform fecal diversion in patients who are acutely ill at presentation. There is a higher morbidity and mortality rate in STM patients. Independent predictors of mortality include CCI, preoperative vasopressor use, steroid use, open abdomen, and intraoperative blood transfusion. Following adjustment by clinical factors, method of colon management was not associated with surgical complications or mortality.Level of evidenceTherapeutic study, level IV.

Published
2020

10. Anticoagulation in emergency general surgery: Who bleeds more? The EAST multicenter trials ACES study

Author

O’Meara, Lindsay, Zhang, Ashling, Baum, Jeffrey N., Cooper, Amanda, Decker, Cassandra, Schroeppel, Thomas, Cai, Jenny, Cullinane, Daniel C., Catalano, Richard D., Bugaev, Nikolay, LeClair, Madison J., Feather, Cristina, McBride, Katherine, Sams, Valerie, Leung, Pak Shan, Olafson, Samantha, Callahan, Devon S., Posluszny, Joseph, Moradian, Simon, Estroff, Jordan, Hochman, Beth, Coleman, Natasha L., Goldenberg-Sandau, Anna, Nahmias, Jeffry, Rosenbaum, Kathryn, Pasley, Jason D., Boll, Lindsay, Hustad, Leah, Reynolds, Jessica, Truitt, Michael, Vesselinov, Roumen, and Ghneim, Mira

Published
2023
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11. “The Why & How Our Trauma Patients Die

Author

Callcut, Rachael A, Kornblith, Lucy Z, Conroy, Amanda S, Robles, Anamaria J, Meizoso, Jonathan P, Namias, Nicholas, Meyer, David E, Haymaker, Amanda, Truitt, Michael S, Agrawal, Vaidehi, Haan, James M, Lightwine, Kelly L, Porter, John M, San Roman, Janika L, Biffl, Walter L, Hayashi, Michael S, Sise, Michael J, Badiee, Jayraan, Recinos, Gustavo, Inaba, Kenji, Schroeppel, Thomas J, Callaghan, Emma, Dunn, Julie A, Godin, Samuel, McIntyre, Robert C, Peltz, Erik D, O’Neill, Patrick J, Diven, Conrad F, Scifres, Aaron M, Switzer, Emily E, West, Michaela A, Storrs, Sarah, Cullinane, Daniel C, Cordova, John F, Moore, Ernest E, Moore, Hunter B, Privette, Alicia R, Eriksson, Evert A, and Cohen, Mitchell Jay

Subjects
Biomedical and Clinical Sciences, Clinical Sciences, Traumatic Head and Spine Injury, Physical Injury - Accidents and Adverse Effects, Brain Disorders, Neurosciences, Traumatic Brain Injury (TBI), Clinical Research, Injuries and accidents, Good Health and Well Being, Accidental Falls, Adult, Age Factors, Aged, Brain Injuries, Traumatic, Cause of Death, Emergency Medical Services, Exsanguination, Female, Humans, Kaplan-Meier Estimate, Male, Middle Aged, Prospective Studies, Risk Factors, Sex Factors, Statistics, Nonparametric, Time Factors, Trauma Centers, Wounds and Injuries, Wounds, Gunshot, Hemorrhage, cause of death, exsanguination, Western Trauma Association Multicenter Study Group, Clinical sciences, Nursing
Abstract

BackgroundHistorically, hemorrhage has been attributed as the leading cause (40%) of early death. However, a rigorous, real-time classification of the cause of death (COD) has not been performed. This study sought to prospectively adjudicate and classify COD to determine the epidemiology of trauma mortality.MethodsEighteen trauma centers prospectively enrolled all adult trauma patients at the time of death during December 2015 to August 2017. Immediately following death, attending providers adjudicated the primary and contributing secondary COD using standardized definitions. Data were confirmed by autopsies, if performed.ResultsOne thousand five hundred thirty-six patients were enrolled with a median age of 55 years (interquartile range, 32-75 years), 74.5% were male. Penetrating mechanism (n = 412) patients were younger (32 vs. 64, p < 0.0001) and more likely to be male (86.7% vs. 69.9%, p < 0.0001). Falls were the most common mechanism of injury (26.6%), with gunshot wounds second (24.3%). The most common overall primary COD was traumatic brain injury (TBI) (45%), followed by exsanguination (23%). Traumatic brain injury was nonsurvivable in 82.2% of cases. Blunt patients were more likely to have TBI (47.8% vs. 37.4%, p < 0.0001) and penetrating patients exsanguination (51.7% vs. 12.5%, p < 0.0001) as the primary COD. Exsanguination was the predominant prehospital (44.7%) and early COD (39.1%) with TBI as the most common later. Penetrating mechanism patients died earlier with 80.1% on day 0 (vs. 38.5%, p < 0.0001). Most deaths were deemed disease-related (69.3%), rather than by limitation of further aggressive care (30.7%). Hemorrhage was a contributing cause to 38.8% of deaths that occurred due to withdrawal of care.ConclusionExsanguination remains the predominant early primary COD with TBI accounting for most deaths at later time points. Timing and primary COD vary significantly by mechanism. Contemporaneous adjudication of COD is essential to elucidate the true understanding of patient outcome, center performance, and future research.Level of evidenceEpidemiologic, level II.

Published
2019

12. Trauma ICU Prevalence Project: the diversity of surgical critical care

Author

Michetti, Christopher P, Fakhry, Samir M, Brasel, Karen, Martin, Niels D, Teicher, Erik J, Newcomb, Anna, Stewart, Amy, Chang, Grace, Foreman, Michael, Rainey, Evan Elizabeth, Moore, Forrest O, Huang, Jessica, Kaups, Krista, Dirks, Rachel C, Sensenig, Rachel L, San Roman, Janika L, Burlew, Clay Cothren, Campion, Eric M, Weireter, Len, Kelley, Katherine, Kim, Dennis, Howell, Erin, Hu, Charles, Lewandowski, Karen, Liu, Chang, Dauer, Elizabeth D, Mukherjee, Kaushik, Penaloza, Liz G, Cullinane, Daniel C, Carrick, Matthew M, Agrawal, Vaidehi, Lorenzo, Manuel, Ferrari-Light, Dana, Coomaraswamy, Michael, West, Michaela A, Farhat, Joseph, Brasel, Karen J, Ballou, Jessica H, Drumheller, Byron C, Radowsky, Jason, Dries, David J, Ramey, Elizabeth, Goulet, Nicole, Livingston, David H, Meizoso, Jonathan P, Zakrison, Tanya L, Wahl, Wendy L, Brandt, Mary-Margaret, Nasrallah, Fady S, Schaffer, Kathryn B, Sakran, Joseph V, Kodadek, Lisa M, Cardenas, Tatiana CP, Rani, Meenakshi, Khan, Abid, Moskowitz, Elisa, Costantini, Todd W, Doucet, Jay J, Schroeppel, Thomas, Corey, Katherine, Pederson, Claire, Martin, Kevin H, Bosarge, Patrick L, Farley, Paige, Nahmias, Jeffry, Grigorian, Areg, Crandall, Marie, Mull, Jennifer, Efron, Philip A, Davis, Ruth, Berdel, Henrik, Culpepper, Chris, West, Sonlee D, Keiler-Green, Ashley, Tung, Lily, Sperry, Jason L, Anto, Vincent P, Nirula, Ram, Buhavac, Milos, Dultz, Linda Ann, Podbielski, Jeanette, Kao, Lillian, Adams, Reanna, Romero, Javier, Diaz, Graal, Bochicchio, Grant V, Rasane, Rohit K, Maung, Adrian A, Hill, Casey, Campbell, Andre, and Stey, Anne

Subjects
Biomedical and Clinical Sciences, Clinical Sciences, Physical Injury - Accidents and Adverse Effects, Patient Safety, Clinical Research, 7.3 Management and decision making, Management of diseases and conditions, Good Health and Well Being, surgical critical care, prevalence study, trauma intensive care unit, ICU mortality, critical care diagnoses, TRIPP study group
Abstract

BackgroundSurgical critical care is crucial to the care of trauma and surgical patients. This study was designed to provide a contemporary assessment of patient types, injuries, and conditions in intensive care units (ICU) caring for trauma patients.MethodsThis was a multicenter prevalence study of the American Association for the Surgery of Trauma; data were collected on all patients present in participating centers' trauma ICU (TICU) on November 2, 2017 and April 10, 2018.ResultsForty-nine centers submitted data on 1416 patients. Median age was 58 years (IQR 41-70). Patient types included trauma (n=665, 46.9%), non-trauma surgical (n=536, 37.8%), medical (n=204, 14.4% overall), or unspecified (n=11). Surgical intensivists managed 73.1% of patients. Of ICU-specific diagnoses, 57% were pulmonary related. Multiple high-intensity diagnoses were represented (septic shock, 10.2%; multiple organ failure, 5.58%; adult respiratory distress syndrome, 4.38%). Hemorrhagic shock was seen in 11.6% of trauma patients and 6.55% of all patients. The most common traumatic injuries were rib fractures (41.6%), brain (38.8%), hemothorax/pneumothorax (30.8%), and facial fractures (23.7%). Forty-four percent were on mechanical ventilation, and 17.6% had a tracheostomy. One-third (33%) had an infection, and over half (54.3%) were on antibiotics. Operations were performed in 70.2%, with 23.7% having abdominal surgery. At 30 days, 5.4% were still in the ICU. Median ICU length of stay was 9 days (IQR 4-20). 30-day mortality was 11.2%.ConclusionsPatient acuity in TICUs in the USA is very high, as is the breadth of pathology and the interventions provided. Non-trauma patients constitute a significant proportion of TICU care. Further assessment of the global predictors of outcome is needed to inform the education, research, clinical practice, and staffing of surgical critical care providers.Level of evidenceIV, prospective observational study.

Published
2019

13. Early VTE prophylaxis in severe traumatic brain injury: A propensity score weighted EAST multicenter study

Author

Ratnasekera, Asanthi M., Kim, Daniel, Seng, Sirivan S., Jacovides, Christina, Kaufman, Elinore J., Sadek, Hannah M., Perea, Lindsey L., Monaco, Christina, Shnaydman, Ilya, Lee, Alexandra Jeongyoon, Sharp, Victoria, Miciura, Angela, Trevizo, Eric, Rosenthal, Martin, Lottenberg, Lawrence, Zhao, William, Keininger, Alicia, Hunt, Michele, Cull, John, Balentine, Chassidy, Egodage, Tanya, Mohamed, Aleem, Kincaid, Michelle, Doris, Stephanie, Cotterman, Robert, Seegert, Sara, Jacobson, Lewis E., Williams, Jamie, Whitmill, Melissa, Palmer, Brandi, Mentzer, Caleb, Tackett, Nichole, Hranjec, Tjasa, Dougherty, Thomas, Morrissey, Shawna, Donatelli-Seyler, Lauren, Rushing, Amy, Tatebe, Leah C., Nevill, Tiffany J., Aboutanos, Michel B., Hamilton, David, Redmond, Diane, Cullinane, Daniel C., Falank, Carolyne, McMellen, Mark, Duran, Christ, Daniels, Jennifer, Ballow, Shana, Schuster, Kevin, and Ferrada, Paula

Published
2023
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14. Failure rates of nonoperative management of low-grade splenic injuries with active extravasation: an Eastern Association for the Surgery of Trauma multicenter study

Author

Spoor, Kristen, primary, Cull, John David, additional, Otaibi, Banan W, additional, Hazelton, Joshua P, additional, Chipko, John, additional, Reynolds, Jessica, additional, Fugate, Sam, additional, Pederson, Claire, additional, Zier, Linda B, additional, Jacobson, Lewis E, additional, Williams, Jamie M, additional, Easterday, Thomas S, additional, Byerly, Saskya, additional, Mentzer, Caleb, additional, Hawke, Edward, additional, Cullinane, Daniel C, additional, Ontengco, Julianne B, additional, Bugaev, Nikolay, additional, LeClair, Madison, additional, Udekwu, Pascal, additional, Josephs, Cooper, additional, Noorbaksh, Matthew, additional, Babowice, James, additional, Velopulos, Catherine Garrison, additional, Urban, Shane, additional, Goldenberg, Anna, additional, Ghobrial, Gaby, additional, Pickering, John M, additional, Quarfordt, Steven D, additional, Aunchman, Alia F, additional, LaRiccia, Aimee K, additional, Spalding, Chance, additional, Catalano, Richard D, additional, Basham, Jordan E, additional, Edmundson, Philip M, additional, Nahmias, Jeffry, additional, Tay, Erika, additional, Norwood, Scott H, additional, Meadows, Katelyn, additional, Wong, Yee, additional, and Hardman, Claire, additional

Published
2024
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15. Unplanned readmission after emergency laparotomy: A post hoc analysis of an EAST multicenter study

Author

Aicher, Brittany O., Diaz, Jose J., Jr., O'Meara, Lindsay B., Decker, Cassandra, Rodriquez, Jennifer, Schroeppel, Thomas, Rattan, Rishi, Vasileiou, Georgia, Yeh, Daniel Dante, Simonoski, Ursula J., Turay, David, Cullinane, Daniel C., Emmert, Cory B., McCrum, Marta L., Wall, Natalie, Badach, Jeremy, Goldenberg-Sandau, Anna, Carmichael, Heather, Velopulos, Catherine, Choron, Rachel, Sakran, Joseph V., Bekdache, Khaldoun, Black, George, Shoultz, Thomas, Chadnick, Zachary, Sim, Vasiliy, Madbak, Firas, Steadman, Daniel, Camazine, Maraya, Zielinski, Martin D., Hardman, Claire, Walusimbi, Mbaga, Kim, Mirhee, Rodier, Simon, Papadopoulos, Vasileios N., Tsoulfas, Georgios, Perez, Javier Martin, Kongkaewpaisan, Napaporn, El Hechi, Majed W., Naar, Leon, and Kaafarani, Haytham M.A.

Published
2021
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16. Anticoagulation therapy in patients with traumatic brain injury: An Eastern Association for the Surgery of Trauma multicenter prospective study

Author

Lomangino, Cara Diaz, Massetti, Jennifer, Glass, Nina E., Livingston, David H., O’Bosky, Karen, Chan, Julie L., Cullinane, Daniel C., Rippey, Kelly A., Sharma, Jyoti, Nahmias, Jeffry, Grigorian, Areg, Allen, Steven, Armen, Scott B., Berne, John D., Mederos, Dalier, Pascual, Jose L., Resnick, Shelby, Bholat, Omar, Ostry, Lauren, Garcia, Luis J., Vecchio, Rafael Ramos, Winston, Eleanor S., Sabour, Andrew F., Matsushima, Kazuhide, Leichtle, Stefan W., Wild, Jeffrey, Young, Katelyn, Chang, Grace, and Demetriades, Demetrios

Published
2021
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17. Increased risk of malignancy for patients older than 40 years with appendicitis and an appendix wider than 10 mm on computed tomography scan: A post hoc analysis of an EAST multicenter study

Author

Alouidor, Reginald, Hing, Kailyn Kwong, Sharp, Victoria, Serena, Thomas, Allmond, Stacie L., Long, Bruce, Barth, Nadine, San Roman, Janika, Lawless, Ryan A., Cralley, Alexis L., Gelbard, Rondi, Szczepanski, Crystal, Eyer, Steven, Proulx, Kaitlyn, Wild, Jeffrey, Young, Katelyn A., Teicher, Erik J., Lita, Elena, Morris, David, Juarez, Laura, Catalano, Richard D., Turay, David, Cullinane, Daniel C., Roberts, Jennifer C., Eid, Ahmed I., Ray-Zack, Mohamed, Kana’an, Tala, Portillo, Victor, Collom, Morgan, Dodgion, Chris, Eddine, Savo Bou Zein, Tabrizi, Maryam B., Elsharkawy, Ahmed Elsayed Mohammed, Evans, David C., Vazquez, Daniel E., Saxe, Jonathan, Jacobson, Lewis, Behrens, Brandon, Schreiber, Martin, Joseph, Bellal, Zeeshan, Muhammad, Nahmias, Jeffry, Sun, Beatrice, Crandall, Marie, Mull, Jennifer, Pasley, Jason D., O’Meara, Lindsay, Gok, Ali Fuat Kann, To, Jocelyn, Rodriguez, Carlos, Bradley, Matthew, Naar, Leon, Kim, Peter, Byerly, Saskya, Vasileiou, Georgia, Zhang, Hang, Yeh, D. Dante, and Kaafarani, Haytham M.A.

Published
2020
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18. Bone Anchor Fixation in the Repair of Blunt Traumatic Abdominal Wall Hernias: A Western Trauma Association Multicenter Study

Author

Harrell, Kevin N, primary, Grimes, Arthur D, additional, Gill, Harkanwar, additional, Reynolds, Jessica K, additional, Ueland, Walker R, additional, Sciarretta, Jason D, additional, Todd, Samual R, additional, Trust, Marc D, additional, Ngoue, Marielle, additional, Thomas, Bradley W, additional, Ayuso, Sullivan A, additional, LaRiccia, Aimee, additional, Spalding, Chance M, additional, Collins, Michael J, additional, Collier, Bryan R, additional, Karam, Basil S, additional, de Moya, Marc A, additional, Lieser, Mark J, additional, Chipko, John M, additional, Haan, James M, additional, Lightwine, Kelly L, additional, Cullinane, Daniel C, additional, Falank, Carolyne R, additional, Phillips, Ryan C, additional, Kemp, Michael T, additional, Alam, Hasan B, additional, Udekwu, Pascal O, additional, Sanin, Gloria D, additional, Hildreth, Amy N, additional, Biffl, Walter L, additional, Schaffer, Kathryn B, additional, Marshall, Gary, additional, Muttalib, Omaer, additional, Nahmias, Jeffry, additional, Shahi, Niti, additional, Moulton, Steven L, additional, and Maxwell, Robert A, additional

Published
2024
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19. EAST MCT: COMPARISON OF PRE-INJURY ANTITHROMBOTIC USE AND REVERSAL STRATEGIES AMONG SEVERE TBI PATIENTS

Author

Yorkgitis, Brian K., Tatum, Danielle M., Taghavi, Sharven, Schroeppel, Thomas J., Noorbakhsh, Matthew R., Hite Philps, Frances, Bugaev, Nikolay, Mukherjee, Kaushik, Bellora, Mellody, Ong, Adrian W., Ratnasekera, Asanthi, Nordham, Kristen D., Carrick, Matthew M., Haan, James M., Lightwine, Kelly L., Lottenberg, Lawrence, Borrego, Robert, Cullinane, Daniel C., Berne, John D., Rodriguez Mederos, Dalier, Hayward, Thomas Z., III, Tfrin, Ian, Kerwin, Andy J, and Crandall, Marie

Published
2021
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21. Eastern Association for the Surgery of Trauma Multicenter Trial: Comparison of pre-injury antithrombotic use and reversal strategies among severe traumatic brain injury patients

Author

Yorkgitis, Brian K., Tatum, Danielle M., Taghavi, Sharven, Schroeppel, Thomas J., Noorbakhsh, Matthew R., Philps, Frances Hite, Bugaev, Nikolay, Mukherjee, Kaushik, Bellora, Mellody, Ong, Adrian W., Ratnasekera, Asanthi, Nordham, Kristen D., Carrick, Matthew M., Haan, James M., Lightwine, Kelly L., Lottenberg, Lawrence, Borrego, Robert, Cullinane, Daniel C., Berne, John D., Rodriguez Mederos, Dalier, Hayward, Thomas Z., III, Kerwin, Andy J., and Crandall, Marie

Published
2022
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23. Management of blunt traumatic abdominal wall hernias: A Western Trauma Association multicenter study

Author

Harrell, Kevin N., Grimes, Arthur D., Albrecht, Roxie M., Reynolds, Jessica K., Ueland, Walker R., Sciarretta, Jason D., Todd, Samual R., Trust, Marc D., Ngoue, Marielle, Thomas, Bradley W., Ayuso, Sullivan A., LaRiccia, Aimee, Spalding, M. Chance, Collins, Michael J., Collier, Bryan R., Karam, Basil S., de Moya, Marc A., Lieser, Mark J., Chipko, John M., Jr, Haan, James M., Lightwine, Kelly L., Cullinane, Daniel C., Falank, Carolyne R., Phillips, Ryan C., Kemp, Michael T., Alam, Hasan B., Udekwu, Pascal O., Sanin, Gloria D., Hildreth, Amy N., Biffl, Walter L., Schaffer, Kathryn B., Marshall, Gary, Muttalib, Omaer, Nahmias, Jeffry, Shahi, Niti, Moulton, Steven L., and Maxwell, Robert A.

Published
2021
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24. A Western Trauma Association Multicenter Comparison of Mesh Versus Non-Mesh Repair of Blunt Traumatic Abdominal Wall Hernia

Author

Harrell, Kevin N, primary, Grimes, Arthur D, additional, Gill, Harkanwar, additional, Reynolds, Jessica K, additional, Ueland, Walker R, additional, Sciarretta, Jason D, additional, Todd, Samual R, additional, Trust, Marc D, additional, Ngoue, Marielle, additional, Thomas, Bradley W, additional, Ayuso, Sullivan A, additional, LaRiccia, Aimee, additional, Spalding, M Chance, additional, Collins, Michael J, additional, Collier, Bryan R, additional, Karam, Basil S, additional, de Moya, Marc A, additional, Lieser, Mark J, additional, Chipko, John M, additional, Haan, James M, additional, Lightwine, Kelly L, additional, Cullinane, Daniel C, additional, Falank, Carolyne R, additional, Phillips, Ryan C, additional, Kemp, Michael T, additional, Alam, Hasan B, additional, Udekwu, Pascal O, additional, Sanin, Gloria D, additional, Hildreth, Amy N, additional, Biffl, Walter L, additional, Schaffer, Kathryn B, additional, Marshall, Gary, additional, Muttalib, Omaer, additional, Nahmias, Jeffry, additional, Shahi, Niti, additional, Moulton, Steven L, additional, and Maxwell, Robert A, additional

Published
2023
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26. The incidence of venous thromboembolic events in trauma patients after tranexamic acid administration: an EAST multicenter study

Author

Rivas, Lisbi, Estroff, Jordan, Sparks, Andrew, Nahmias, Jeffry, Allen, Rebecca, Smith, Savannah R., Kutcher, Matthew, Carter, Kristen, Grigorian, Areg, Albertson, Spencer, Turay, David, Quispe, Juan C., Luo-Owen, Xian, Vella, Michael, Pascual, Jose, Tororello, Gabriella, Quattrone, McKell, Bernard, Andrew, Ratnasekera, Ashanthi, Lee, Alice, Tamburrini, Danielle, Rodriguez, Carlos, Harrell, Kelly, Jeyamurugan, Kokila, Bugaev, Nikolay, Warner, Anne, Weinberger, Jason, Hazelton, Joshua P., Selevany, Mariam, Wright, Franklin, Kovar, Alexandra, Urban, Shane, Hamrick, Amy, Mount, Michael, Carrick, Matthew, Cullinane, Daniel C., Chang, Grace, Jain, Gary, Spalding, Chance, and Sarani, Babak

Published
2021
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27. Prospective validation of the Emergency Surgery Score in emergency general surgery: An Eastern Association for the Surgery of Trauma multicenter study

Author

Kaafarani, Haytham M.A., Kongkaewpaisan, Napaporn, Aicher, Brittany O., Diaz, Jose J., Jr., OʼMeara, Lindsay B., Decker, Cassandra, Rodriquez, Jennifer, Schroeppel, Thomas, Rattan, Rishi, Vasileiou, Georgia, Yeh, D. Dante, Simonoski, Ursula J., Turay, David, Cullinane, Daniel C., Emmert, Cory B., McCrum, Marta L., Wall, Natalie, Badach, Jeremy, Goldenberg-Sandau, Anna, Carmichael, Heather, Velopulos, Catherine, Choron, Rachel, Sakran, Joseph V., Bekdache, Khaldoun, Black, George, Shoultz, Thomas, Chadnick, Zachary, Sim, Vasiliy, Madbak, Firas, Steadman, Daniel, Camazine, Maraya, Zielinski, Martin D., Hardman, Claire, Walusimbi, Mbaga, Kim, Mirhee, Rodier, Simon, Papadopoulos, Vasileios N., Tsoulfas, Georgios, Perez, Javier Martin, and Velmahos, George C.

Published
2020
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28. Early VTE Prophylaxis in Severe Traumatic Brain Injury: A Propensity Score Weighted EAST Multi-Center Study

Author

Ratnasekera, Asanthi M., primary, Kim, Daniel, additional, Seng, Sirivan S., additional, Jacovides, Christina, additional, Kaufman, Elinore J., additional, Sadek, Hannah M., additional, Perea, Lindsey L., additional, Monaco, Christina, additional, Shnaydman, Ilya, additional, Jeongyoon Lee, Alexandra, additional, Sharp, Victoria, additional, Miciura, Angela, additional, Trevizo, Eric, additional, Rosenthal, Martin, additional, Lottenberg, Lawrence, additional, Zhao, William, additional, Keininger, Alicia, additional, Hunt, Michele, additional, Cull, John, additional, Balentine, Chassidy, additional, Egodage, Tanya, additional, Mohamed, Aleem, additional, Kincaid, Michelle, additional, Doris, Stephanie, additional, Cotterman, Robert, additional, Seegert, Sara, additional, Jacobson, Lewis E., additional, Williams, Jamie, additional, Whitmill, Melissa, additional, Palmer, Brandi, additional, Mentzer, Caleb, additional, Tackett, Nichole, additional, Hranjec, Tjasa, additional, Dougherty, Thomas, additional, Morrissey, Shawna, additional, Donatelli-Seyler, Lauren, additional, Rushing, Amy, additional, Tatebe, Leah C., additional, Nevill, Tiffany J., additional, Aboutanos, Michel B., additional, Hamilton, David, additional, Redmond, Diane, additional, Cullinane, Daniel C., additional, Falank, Carolyne, additional, McMellen, Mark, additional, Duran, Christ, additional, Daniels, Jennifer, additional, Ballow, Shana, additional, Schuster, Kevin, additional, and Ferrada, Paula, additional

Published
2023
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29. The why and how our trauma patients die: A prospective Multicenter Western Trauma Association study

Author

Callcut, Rachael A., Kornblith, Lucy Z., Conroy, Amanda S., Robles, Anamaria J., Meizoso, Jonathan P., Namias, Nicholas, Meyer, David E., Haymaker, Amanda, Truitt, Michael S., Agrawal, Vaidehi, Haan, James M., Lightwine, Kelly L., Porter, John M., San Roman, Janika L., Biffl, Walter L., Hayashi, Michael S., Sise, Michael J., Badiee, Jayraan, Recinos, Gustavo, Inaba, Kenji, Schroeppel, Thomas J., Callaghan, Emma, Dunn, Julie A., Godin, Samuel, McIntyre, Robert C., Jr, Peltz, Erik D., OʼNeill, Patrick J., Diven, Conrad F., Scifres, Aaron M., Switzer, Emily E., West, Michaela A., Storrs, Sarah, Cullinane, Daniel C., Cordova, John F., Moore, Ernest E., Moore, Hunter B., Privette, Alicia R., Eriksson, Evert A., and Cohen, Mitchell Jay

Published
2019
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30. Management of penetrating intraperitoneal colon injuries: A meta-analysis and practice management guideline from the Eastern Association for the Surgery of Trauma

Author

Cullinane, Daniel C., Jawa, Randeep S., Como, John J., Moore, Ashlee E., Morris, David S., Cheriyan, Jerry, Guillamondegui, Oscar D., Goldberg, Stephanie R., Petrey, Laura, Schaefer, Gregory P., Khwaja, Kosar A., Rowell, Susan E., Barbosa, Ronald R., Bass, Gary A., Kasotakis, George, and Robinson, Bryce R.H.

Published
2019
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31. Anticoagulation in emergency general surgery: Who bleeds more? The EAST multicenter trials ACES study.

Author

O'Meara, Lindsay, Zhang, Ashling, Baum, Jeffrey N., Cooper, Amanda, Decker, Cassandra, Schroeppel, Thomas, Cai, Jenny, Cullinane, Daniel C., Catalano, Richard D., Bugaev, Nikolay, LeClair, Madison J., Feather, Cristina, McBride, Katherine, Sams, Valerie, Pak Shan Leung, Olafson, Samantha, Callahan, Devon S., Posluszny, Joseph, Moradian, Simon, and Estroff, Jordan

Published
2023
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32. Risk factors for recurrence in blunt traumatic abdominal wall hernias: A secondary analysis of a Western Trauma association multicenter study

Author

Harrell, Kevin N., primary, Grimes, Arthur D., additional, Gill, Harkanwar, additional, Reynolds, Jessica K., additional, Ueland, Walker R., additional, Sciarretta, Jason D., additional, Todd, Samual R., additional, Trust, Marc D., additional, Ngoue, Marielle, additional, Thomas, Bradley W., additional, Ayuso, Sullivan A., additional, LaRiccia, Aimee, additional, Spalding, M Chance, additional, Collins, Michael J., additional, Collier, Bryan R., additional, Karam, Basil S., additional, de Moya, Marc A., additional, Lieser, Mark J., additional, Chipko, John M., additional, Haan, James M., additional, Lightwine, Kelly L., additional, Cullinane, Daniel C., additional, Falank, Carolyne R., additional, Phillips, Ryan C., additional, Kemp, Michael T., additional, Alam, Hasan B., additional, Udekwu, Pascal O., additional, Sanin, Gloria D., additional, Hildreth, Amy N., additional, Biffl, Walter L., additional, Schaffer, Kathryn B., additional, Marshall, Gary, additional, Muttalib, Omaer, additional, Nahmias, Jeffry, additional, Shahi, Niti, additional, Moulton, Steven L., additional, and Maxwell, Robert A., additional

Published
2022
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33. Time to stroke: A Western Trauma Association multicenter study of blunt cerebrovascular injuries

Author

Burlew, Clay Cothren, Sumislawski, Joshua J., Behnfield, Charles D., McNutt, Michelle K., McCarthy, James, Sharpe, John P., Croce, Martin A., Bala, Miklosh, Kashuk, Jeffry, Spalding, M. Chance, Beery, Paul R., John, Scott, Hunt, Darren J., Harmon, Laura, Stein, Deborah M., Callcut, Rachael, Wybourn, Chris, Sperry, Jason, Anto, Vincent, Dunn, Julie, Veith, Jacob P., Brown, Carlos V. R., Celii, Amanda, Zander, Tyler L., Coimbra, Raul, Berndtson, Allison E., Moss, Tovah Z., Malhotra, Ajai K., Hazelton, Joshua P., Linden, Kimberly, West, Michaela, Alam, Hasan B., Williams, Aaron M., Kim, Jennie, Inaba, Kenji, Moulton, Steve, Choi, Young Mee, Warren, Harry L., Collier, Bryan, Ball, Chad G., Savage, Stephanie, Hartwell, Jennifer L., Cullinane, Daniel C., Zielinski, Martin D., Ray-Zack, Mohamed D., Morse, Bryan C., Rhee, Peter, Rutherford, Edmund J., Udekwu, Pascal, Reynolds, Cassandra, Toschlog, Eric, Gondek, Steve, Ju, Tammy, Haan, James M., Lightwine, Kelly L., Kulvatunyou, Narong, Coates, Brian, Khouqeer, Ahmed F., Todd, S. Rob, Zarzaur, Ben, Waller, Christine J., Kallies, Kara J., Neideen, Todd, Eddine, Savo Bou Zein, Peck, Kimberly A., Dunne, Casey E., Kramer, Kristina, Bokhari, Faran, Dhillon, Tejveer S., Galante, Joseph M., and Cohen, Mitchell J.

Published
2018
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34. EAST Multicenter Trial on targeted temperature management for hanging-induced cardiac arrest

Author

Hsu, Cindy H., Haac, Bryce E., Drake, Mack, Bernard, Andrew C., Aiolfi, Alberto, Inaba, Kenji, Hinson, Holly E., Agarwal, Chinar, Galante, Joseph, Tibbits, Emily M., Johnson, Nicholas J., Carlbom, David, Mirhoseini, Mina F., Patel, Mayur B., OʼBosky, Karen R., Chan, Christian, Udekwu, Pascal O., Farrell, Megan, Wild, Jeffrey L., Young, Katelyn A., Cullinane, Daniel C., Gojmerac, Deborah J., Weissman, Alexandra, Callaway, Clifton, Perman, Sarah M., Guerrero, Mariana, Aisiku, Imoigele P., Seethala, Raghu R., Co, Ivan N., Madhok, Debbie Y., Darger, Bryan, Kim, Dennis Y., Spence, Lara, Scalea, Thomas M., and Stein, Deborah M.

Published
2018
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36. The American Association for the Surgery of Trauma Severity Grade is valid and generalizable in adhesive small bowel obstruction

Author

Hernandez, Matthew C., Haddad, Nadeem N., Cullinane, Daniel C., Yeh, D. Dante, Wydo, Salina, Inaba, Kenji, Duane, Therese M., Pakula, Andrea, Skinner, Ruby, Rodriguez, Carlos J., Dunn, Julie, Sams, Valerie G., Zielinski, Martin D., Choudhry, Asad, Turay, David, Yune, Ji-Ming, Watras, Jill, Widom, Kenneth A., Cull, John, Toschlog, Eric A., and Graybill, John C.

Published
2018
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37. Contemporary management of subclavian and axillary artery injuries—A Western Trauma Association multicenter review

Author

Waller, Christine J., Cogbill, Thomas H., Kallies, Kara J., Ramirez, Luis D., Cardenas, Justin M., Todd, S. Rob, Chapman, Kayla J., Beckman, Marshall A., Sperry, Jason L., Anto, Vincent P., Eriksson, Evert A., Leon, Stuart M., Anand, Rahul J., Pearlstein, Maura, Capano-Wehrle, Lisa, Cothren Burlew, Clay, Fox, Charles J., Cullinane, Daniel C., Roberts, Jennifer C., Harrison, Paul B., Berg, Gina M., Haan, James M., and Lightwine, Kelly

Published
2017
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38. Outcomes of Protocol-Driven Venous Thromboembolic Chemo-Prophylaxis in Trauma Patients: A Trauma Quality Improvement Project Analysis

Author

Kyros, Peter N., Sheppard, Forest R., Sawhney, Jaswin S., Cullinane, Daniel C., Falank, Carolyne R., Smith, Kathryn E., Ontengco, Julianne B., Turner, Elizabeth N., Chung, Bruce, Shurtleff, Eric, and Morse, Bryan C.

Abstract

Introduction Low molecular weight heparin (LMWH) is the standard for venous thromboembolic (VTE) chemo-prophylaxis in trauma patients; however, inconsistencies in the use of LMWH exist. The objective of this study was to assess VTE outcomes in response to a chemo-prophylaxis protocol guided by patient physiology (eg, creatinine clearance) and comorbidities.Methods ACS TQIP Benchmark Reports at a level 1 trauma center using a patient physiology and comorbidity directed VTE chemo-prophylaxis protocol were analyzed for Spring 2019 to Fall 2021. Patient demographics, VTE rates and pharmacologic VTE prophylaxis type were collected for “All Patients” and “Elderly” (TQIP: age ≥ 55 years) cohorts.Results Data was analyzed for 1919183 “All Hospitals” (AH) and 5843 patients single institution (SI) using the physiologic and comorbidity guided VTE chemo-prophylaxis protocol. Elderly subgroup had 701965 (AH) and 2939 (SI) patients. Use of non-LMWH chemo-prophylaxis was significantly higher at SI: All patients = 62.6% SI vs 22.1% (P< .01); Elderly = 68.8% SI vs 28.1% AH (P< .01). VTE, DVT, and PE rates for All Patients and Elderly subgroup were significantly reduced at SI, except Elderly PE which was statistically equivalent.Conclusions Protocol-driven VTE chemo-prophylaxis was associated with significantly lower LMWH use accompanied by significant reductions in All VTE, DVT, PE, and Elderly VTE and DVT with no difference in Elderly PE rates. These results may imply that adherence to a physiologic and comorbidity directed chemo-prophylaxis protocol, rather than LMWH, reduces VTE events in trauma patients. Further investigation to elucidate best practice is warranted.

Published
2023
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41. Validation of the American Association for the Surgery of Trauma Emergency General Surgery Grading System for Colorectal Resection: An EAST Multicenter Study

Author

Aicher, Brittany O., primary, Betancourt-Ramirez, Alejandro, additional, Grossman, Michael D., additional, Heise, Holly, additional, Schroeppel, Thomas J., additional, Hernandez, Matthew C., additional, Zielinski, Martin D., additional, Kongkaewpaisan, Napaporn, additional, Kaafarani, Haytham M. A., additional, Wagner, Afton, additional, Grabo, Daniel, additional, Scott, Michael, additional, Peck, Gregory, additional, Chang, Gloria, additional, Matsushima, Kazuhide, additional, Cullinane, Daniel C., additional, Cullinane, Laura M., additional, Stocker, Benjamin, additional, Posluszny, Joseph, additional, Simonoski, Ursula J., additional, Catalano, Richard D., additional, Vasileiou, Georgia, additional, Yeh, Daniel Dante, additional, Agrawal, Vaidehi, additional, Truitt, Michael S., additional, Pickett, MaryAnne, additional, Dultz, Linda, additional, Muller, Alison, additional, Ong, Adrian W., additional, San Roman, Janika L., additional, Barth, Nadine, additional, Fackelmayer, Oliver, additional, Velopulos, Catherine G., additional, Hendrix, Cheralyn, additional, Estroff, Jordan M., additional, Gambhir, Sahil, additional, Nahmias, Jeffry, additional, Jeyamurugan, Kokila, additional, Bugaev, Nikolay, additional, O’Meara, Lindsay, additional, Kufera, Joseph, additional, Diaz, Jose J., additional, and Bruns, Brandon R., additional

Published
2022
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42. sj-pdf-1-asu-10.1177_0003134820960022 ��� Supplemental Material for Validation of the American Association for the Surgery of Trauma Emergency General Surgery Grading System for Colorectal Resection: An EAST Multicenter Study

Author

Aicher, Brittany O., Betancourt-Ramirez, Alejandro, Grossman, Michael D., Heise, Holly, Schroeppel, Thomas J., Hernandez, Matthew C., Zielinski, Martin D., Kongkaewpaisan, Napaporn, Kaafarani, Haytham M. A., Wagner, Afton, Grabo, Daniel, Scott, Michael, Peck, Gregory, Chang, Gloria, Matsushima, Kazuhide, Cullinane, Daniel C., Cullinane, Laura M., Stocker, Benjamin, Posluszny, Joseph, Simonoski, Ursula J., Catalano, Richard D., Vasileiou, Georgia, Yeh, Daniel Dante, Agrawal, Vaidehi, Truitt, Michael S., Pickett, MaryAnne, Dultz, Linda, Muller, Alison, Ong, Adrian W., San Roman, Janika L., Barth, Nadine, Fackelmayer, Oliver, Velopulos, Catherine G., Hendrix, Cheralyn, Estroff, Jordan M., Gambhir, Sahil, Nahmias, Jeffry, Jeyamurugan, Kokila, Bugaev, Nikolay, O���Meara, Lindsay, Kufera, Joseph, Diaz, Jose J., and Bruns, Brandon R.

Subjects
FOS: Clinical medicine, 110323 Surgery
Abstract

Supplemental Material, sj-pdf-1-asu-10.1177_0003134820960022 for Validation of the American Association for the Surgery of Trauma Emergency General Surgery Grading System for Colorectal Resection: An EAST Multicenter Study by Brittany O. Aicher, Alejandro Betancourt-Ramirez, Michael D. Grossman, Holly Heise, Thomas J.Schroeppel, Matthew C.Hernandez, Martin D. Zielinski, Napaporn Kongkaewpaisan, Haytham M. A. Kaafarani, Afton Wagner, Daniel Grabo, Michael Scott, Gregory Peck, Gloria Chang, Kazuhide Matsushima, Daniel C. Cullinane, Laura M. Cullinane, Benjamin Stocker, Joseph Posluszny, Ursula J. Simonoski, Richard D. Catalano, Georgia Vasileiou, D. Dante Yeh, Vaidehi Agrawal, Michael S. Truitt, MaryAnne Pickett, Linda Dultz, Alison Muller, Adrian W. Ong, Janika L. San Roman, Nadine Barth, Oliver Fackelmayer, Catherine G. Velopulos, Cheralyn Hendrix, Jordan M. Estroff, Sahil Gambhir, Jeffry Nahmias, Kokila Jeyamurugan, Nikolay Bugaev, Lindsay O���Meara, Joseph Kufera, Jose J. Diaz and Brandon R. Bruns in The American Surgeon

Published
2022
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43. Revision of the AAST grading scale for acute cholecystitis with comparison to physiologic measures of severity

Author

Schuster, Kevin M., primary, O’Connor, Rick, additional, Cripps, Michael, additional, Kuhlenschmidt, Kali, additional, Taveras, Luis, additional, Kaafarani, Haytham M., additional, El Hechi, Majed, additional, Puri, Ruchir, additional, Schroeppel, Thomas J., additional, Enniss, Toby M., additional, Cullinane, Daniel C., additional, Cullinane, Laura M., additional, Agarwal, Suresh, additional, Kaups, Krista, additional, Crandall, Marie, additional, and Tominaga, Gail, additional

Published
2021
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46. Outcomes after Ultramassive Transfusion in the Modern Era: An EAST Multicenter Study

Author

Matthay, Zachary A., Hellmann, Zane J., Callcut, Rachael A., Matthay, Ellicott C., Nunez-Garcia, Brenda, Duong, William, Nahmias, Jeffry, LaRiccia, Aimee K., Spalding, M. Chance, Dalavayi, Satya S., Reynolds, Jessica K., Lesch, Heather, Wong, Yee, Chipman, Amanda, Kozar, Rosemary A., Penaloza, Liz, Mukherjee, Kaushik, Taghlabi, Khaled, Guidry, Christopher A., Seng, Sirivan S., Ratnasekera, Asanthi, Motameni, Amirreza, Udekwu, Pascal, Madden, Kathleen, Moore, Sarah A., Kirsch, Jordan, Goddard, Jesse, Haan, James, Lightwine, Kelly, Ontengco, Julianne B., Cullinane, Daniel C., Spitzer, Sarabeth A., Kubasiak, John C., Gish, Joshua, Hazelton, Joshua P., Byskosh, Alexandria Z., Posluszny, Joseph A., and Kornblith, Lucy Z.

Subjects
Adult, Male, Resuscitation, Age Factors, Blood Component Transfusion, Hemorrhage, Middle Aged, Prognosis, Thrombocytopenia, Article, Injury Severity Score, Treatment Outcome, Trauma Centers, Risk Factors, Humans, Wounds and Injuries, Female, Glasgow Coma Scale, Hospital Mortality, Retrospective Studies
Abstract

Despite the widespread institution of modern massive transfusion protocols with balanced blood product ratios, survival for patients with traumatic hemorrhage receiving ultramassive transfusion (UMT) (defined as ≥20 U of packed red blood cells [RBCs]) in 24 hours) remains low and resource consumption remains high. Therefore, we aimed to identify factors associated with mortality in trauma patients receiving UMT in the modern resuscitation era.An Eastern Association for the Surgery of Trauma multicenter retrospective study of 461 trauma patients from 17 trauma centers who received ≥20 U of RBCs in 24 hours was performed (2014-2019). Multivariable logistic regression and Classification and Regression Tree analysis were used to identify clinical characteristics associated with mortality.The 461 patients were young (median age, 35 years), male (82%), severely injured (median Injury Severity Score, 33), in shock (median shock index, 1.2; base excess, -9), and transfused a median of 29 U of RBCs, 22 U of fresh frozen plasma (FFP), and 24 U of platelets (PLT). Mortality was 46% at 24 hours and 65% at discharge. Transfusion of RBC/FFP ≥1.5:1 or RBC/PLT ≥1.5:1 was significantly associated with mortality, most pronounced for the 18% of patients who received both RBC/PLT and RBC/FFP ≥1.5:1 (odds ratios, 3.11 and 2.81 for mortality at 24 hours and discharge; both p0.01). Classification and Regression Tree identified that age older than 50 years, low initial Glasgow Coma Scale, thrombocytopenia, and resuscitative thoracotomy were associated with low likelihood of survival (14-26%), while absence of these factors was associated with the highest survival (71%).Despite modern massive transfusion protocols, one half of trauma patients receiving UMT are transfused with either RBC/FFP or RBC/PLT in unbalanced ratios ≥1.5:1, with increased associated mortality. Maintaining focus on balanced ratios during UMT is critical, and consideration of advanced age, poor initial mental status, thrombocytopenia, and resuscitative thoracotomy can aid in prognostication.Prognostic, level III.

Published
2021

47. Eastern Association for the Surgery of Trauma Multicenter Trial: Comparison of pre-injury antithrombotic use and reversal strategies among severe traumatic brain injury patients

Author

Yorkgitis, Brian K., primary, Tatum, Danielle M., additional, Taghavi, Sharven, additional, Schroeppel, Thomas J., additional, Noorbakhsh, Matthew R., additional, Philps, Frances Hite, additional, Bugaev, Nikolay, additional, Mukherjee, Kaushik, additional, Bellora, Mellody, additional, Ong, Adrian W., additional, Ratnasekera, Asanthi, additional, Nordham, Kristen D., additional, Carrick, Matthew M., additional, Haan, James M., additional, Lightwine, Kelly L., additional, Lottenberg, Lawrence, additional, Borrego, Robert, additional, Cullinane, Daniel C., additional, Berne, John D., additional, Rodriguez Mederos, Dalier, additional, Hayward, Thomas Z., additional, Kerwin, Andy J., additional, and Crandall, Marie, additional

Published
2021
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48. Unplanned readmission after emergency laparotomy: A post hoc analysis of an EAST multicenter study

Author

Kongkaewpaisan, Napaporn, primary, El Hechi, Majed W., additional, Naar, Leon, additional, Kaafarani, Haytham M.A., additional, Aicher, Brittany O., additional, Diaz, Jose J., additional, O'Meara, Lindsay B., additional, Decker, Cassandra, additional, Rodriquez, Jennifer, additional, Schroeppel, Thomas, additional, Rattan, Rishi, additional, Vasileiou, Georgia, additional, Yeh, Daniel Dante, additional, Simonoski, Ursula J., additional, Turay, David, additional, Cullinane, Daniel C., additional, Emmert, Cory B., additional, McCrum, Marta L., additional, Wall, Natalie, additional, Badach, Jeremy, additional, Goldenberg-Sandau, Anna, additional, Carmichael, Heather, additional, Velopulos, Catherine, additional, Choron, Rachel, additional, Sakran, Joseph V., additional, Bekdache, Khaldoun, additional, Black, George, additional, Shoultz, Thomas, additional, Chadnick, Zachary, additional, Sim, Vasiliy, additional, Madbak, Firas, additional, Steadman, Daniel, additional, Camazine, Maraya, additional, Zielinski, Martin D., additional, Hardman, Claire, additional, Walusimbi, Mbaga, additional, Kim, Mirhee, additional, Rodier, Simon, additional, Papadopoulos, Vasileios N., additional, Tsoulfas, Georgios, additional, and Perez, Javier Martin, additional

Published
2021
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50. Management of simple and retained hemothorax: A practice management guideline from the Eastern Association for the Surgery of Trauma

Author

Patel, Nimitt J., primary, Dultz, Linda, additional, Ladhani, Husayn A., additional, Cullinane, Daniel C., additional, Klein, Eric, additional, McNickle, Allison G., additional, Bugaev, Nikolay, additional, Fraser, Douglas R., additional, Kartiko, Susan, additional, Dodgion, Chris, additional, Pappas, Peter A., additional, Kim, Dennis, additional, Cantrell, Sarah, additional, Como, John J., additional, and Kasotakis, George, additional

Published
2021
Full Text
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