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2 results on '"Cuncheng, Lou"'

1. Correlation of computed tomography quantitative parameters with tumor invasion and Ki-67 expression in early lung adenocarcinoma

Author

Hao Dong, MD, Lekang Yin, PhD, Cuncheng Lou, MD, Junjie Yang, MD, Xinbin Wang, MD, and Yonggang Qiu, MD

Subjects
Medicine
Abstract

Abstract. The purpose of the study is to investigate the correlation of computed tomography (CT) quantitative parameters with tumor invasion and Ki-67 expression in early lung adenocarcinoma. The study involved 141 lesions in 141 patients with early lung adenocarcinoma. According to the degree of tumor invasion, the lesions were assigned into (adenocarcinoma in situ + minimally invasive adenocarcinoma) group and invasive adenocarcinoma (IAC) group. Artificial intelligence-assisted diagnostic software was used to automatically outline the lesions and extract corresponding quantitative parameters on CT images. Statistical analysis was performed to explore the correlation of these parameters with tumor invasion and Ki-67 expression. The results of logistic regression analysis showed that the short diameter of the lesion and the average CT value were independent predictors of IAC. Receiver operating characteristic curve analysis identified the average CT value as an independent predictor of IAC with the best performance, with the area under the receiver operating characteristic curve of 0.893 (P

Published
2022
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2. Clinical, Pathological and CT Imaging Analysis of AT-AG (Three Cases and Literature Review)

Author

Yonggang, Qiu, Hongsheng, Liu, Yali, Lu, Yingdong, Chen, Yongqiang, Tang, and Cuncheng, Lou

Subjects
drenal tumors, Adenomatoid tumor, Pathology, tomography, X-ray CT
Abstract

Background: Adenomatoid Tumor of the Adrenal Gland (AT-AG) are very rare. As the most commonly used clinical examination program, CT scan can make benign and malignant diagnosis by evaluating the characteristics of lesion shape, density and blood vessels, and provide imaging basis for treatment decisions.Objective: To investigate the clinical, pathological and CT imaging features of AT-AG.Methods: The clinical, pathological and CT findings of three AT-AG patients confirmed by surgery or pathology were reviewed and analyzed with reference to nine cases in literature reports.Results: Among the 12 patients with AT-AG, 11 were male, with a median age of 40 years; 11 were diagnosed by physical examination or accident, while 1 was treated for right lumbago. Pathologically, they were characterized by microcapsule/glandular tube structures, absence of cell heteromorphosis and mitosis, positive immunohistochemical mesothelial markers, and negative endothelial markers; In addition, all of them were confirmed with single adrenal cystic or cystic solid masses on CT, including 2 with multilocular cyst and 3 with calcification. Among them, nine (75%) were oval, with the long diameter parallel to the long axis of adrenal gland, and 8 (67%) showed mild and moderate enhancement of capsule wall and solid components on enhanced scan.Conclusion: AT-AG is more common in young and middle-aged men than other population groups, and it constitutes microcapsule/glandular structures under microscope. Its immune histo chemical mesothelial markers show positive, while endothelial markers are negative. CT findings reveal a mostly oval solitary cyst or solid mass, parallel to the long axis of adrenal gland, with mild and moderate enhancement on enhanced CT scan. Thus, being familiar with the clinical, pathological and CT features of AT-AG helps boost the understanding of the disease

Published
2022

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