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Furthermore, the eruption may be an abortive variant of supravenous hyperpigmentation described with docetaxel previously.4 Interestingly, despite developing fixed erythrodysesthesia at peripheral intravenous insertion sites, our patient did not have the reaction when a central catheter was used. This report serves to alert clinicians to fixed erythrodysesthesia plaques, a rare cutaneous side effect seen in the peripheral intravenous administration of the chemotherapeutic agent docetaxel that potentially may be avoided by infusion via a central venous catheter. Given the ongoing rashes at intravenous insertion sites, an implantable indwelling central intravenous catheter was placed, and the patient did not experience any skin adverse effects after docetaxel infusion through the implanted catheter. [Extracted from the article]

Vaginal symptoms are a common chief complaint amongst women visiting outpatient clinics in rural Haiti. A systematic sample of 206 consecutive women over age 18 with gynaecological symptoms underwent gynaecologic examination and laboratory testing for chlamydia, gonorrhoea, syphilis, HIV infection, trichomoniasis, candidiasis, and bacterial vaginosis. Among 206 women, 174 (84%) presented with vaginal discharge, 165 (80%) with vaginal itching, 123 (60%) with vaginal pain or dysuria, and 18 (9%) with non-traumatic vaginal sores or boils. Laboratory results were positive for Chlamydia trachomatis in 5.4% (11/203), syphilis in 3.5% (7/202), HIV in 1.0% (2/200), and Neisseria gonorrhoeae in 1.0% (2/203). Among those that had microscopy, hyphae suggestive of candidiasis were visualized in 2.2% (1/45) and no cases of trichomoniasis were diagnosed 0% (0/45). Bacterial vaginosis was diagnosed in 28.3% (13/46). The prevalence of chlamydia was 4.9 (95% CI: 1.3–17.7) times greater among those 25 years of age and under (10.8%) than those older (2.3%). Chlamydia and bacterial vaginosis were the most common sexually transmitted infection and vaginal condition, respectively, in this study of rural Haitian adult women. The higher risk of chlamydia in younger women suggests education and screening programmes in young women should be considered. [ABSTRACT FROM PUBLISHER]