417 results on '"Cutruzzolà, Francesca"'
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2. Structure-based mechanism of riboregulation of the metabolic enzyme SHMT1
3. Biliverdin Reductase-A integrates insulin signaling with mitochondrial metabolism through phosphorylation of GSK3β
4. Molecular insights into RmcA-mediated c-di-GMP consumption: Linking redox potential to biofilm morphogenesis in Pseudomonas aeruginosa
5. Targeting the Grb2 cSH3 domain: Design, synthesis and biological evaluation of the first series of modulators
6. A conserved scaffold with heterogeneous metal ion binding site: the multifaceted example of HD-GYP proteins
7. Retinoic acid-induced 1 gene haploinsufficiency alters lipid metabolism and causes autophagy defects in Smith-Magenis syndrome
8. Structure and Function of HD-GYP Phosphodiesterases
9. Modelling of SHMT1 riboregulation predicts dynamic changes of serine and glycine levels across cellular compartments
10. Biophysical characterization of melanoma cell phenotype markers during metastatic progression
11. Combined Delivery of miR-15/16 through Humanized Ferritin Nanocages for the Treatment of Chronic Lymphocytic Leukemia
12. Differential inhibitory effect of a pyrazolopyran compound on human serine hydroxymethyltransferase-amino acid complexes
13. Molecular insights into RmcA-mediated c-di-GMP consumption: linking redox potential to biofilm morphogenesis in Pseudomonas aeruginosa
14. Cytosolic serine hydroxymethyltransferase controls lung adenocarcinoma cells migratory ability by modulating AMP kinase activity
15. The Nitrite Reductase from Pseudomonas aeruginosa: Essential Role of Two Active-Site Histidines in the Catalytic and Structural Properties
16. The Role of Cavities in Protein Dynamics: Crystal Structure of a Photolytic Intermediate of a Mutant Myoglobin
17. Differential 3-bromopyruvate inhibition of cytosolic and mitochondrial human serine hydroxymethyltransferase isoforms, key enzymes in cancer metabolic reprogramming
18. Beyond nitrogen metabolism: nitric oxide, cyclic-di-GMP and bacterial biofilms
19. Extracellular serine empowers epidermal proliferation and psoriasis-like symptoms
20. Retinoic acid-induced 1 gene haploinsufficiency alters lipid metabolism and causes autophagy defects in Smith-Magenis syndrome
21. Serine and glycine metabolism in cancer
22. Discovering Selective Diguanylate Cyclase Inhibitors: From PleD to Discrimination of the Active Site of Cyclic-di-GMP Phosphodiesterases
23. Anticancer Activity of (S)-5-Chloro-3-((3,5-dimethylphenyl)sulfonyl)-N-(1-oxo-1-((pyridin-4-ylmethyl)amino)propan-2-yl)-1H-indole-2-carboxamide (RS4690), a New Dishevelled 1 Inhibitor
24. Nutrient Sensing and Biofilm Modulation: The Example of L-arginine in Pseudomonas
25. CHAPTER 4. Nitrite Reductase – Cytochrome cd1
26. Open conformation of human DOPA decarboxylase reveals the mechanism of PLP addition to Group II decarboxylases
27. In silico and in vitro validation of serine hydroxymethyltransferase as a chemotherapeutic target of the antifolate drug pemetrexed
28. Anticancer Activity of (S)-5-Chloro-3-((3,5-dimethylphenyl)sulfonyl)-N-(1-oxo-1-((pyridin-4-ylmethyl)amino)propan-2-yl)-1H-indole-2-carboxamide (RS4690), a New Dishevelled 1 Inhibitor
29. Distal–proximal crosstalk in the heme binding pocket of the NO sensor DNR
30. The phosphodiesterase RmcA contributes to the adaptation of Pseudomonas putida to l-arginine.
31. Cytosolic localization and in vitro assembly of human de novo thymidylate synthesis complex
32. Structure and metal-binding properties of PA4063, a novel player in periplasmic zinc trafficking byPseudomonas aeruginosa
33. How pyridoxal 5′-phosphate differentially regulates human cytosolic and mitochondrial serine hydroxymethyltransferase oligomeric state
34. Intramolecular Electron Transfer in Pseudomonas aeruginosa cd1 Nitrite Reductase: Thermodynamics and Kinetics
35. The immunosuppressive drug azathioprine inhibits biosynthesis of the bacterial signal molecule cyclic-di-GMP by interfering with intracellular nucleotide pool availability
36. Crystal structure of Aspergillus fumigatusAroH, an aromatic amino acid aminotransferase
37. Metformin Is a Pyridoxal-5′-phosphate (PLP)-Competitive Inhibitor of SHMT2
38. Tyrosine as a redox-active center in electron transfer to ferryl heme in globins
39. NO sensing in Pseudomonas aeruginosa: Structure of the Transcriptional Regulator DNR
40. The Emerging Role of Amino Acids of the Brain Microenvironment in the Process of Metastasis Formation
41. High-Fat Diet Leads to Reduced Protein O-GlcNAcylation and Mitochondrial Defects Promoting the Development of Alzheimer’s Disease Signatures
42. Fast Dissociation of Nitric Oxide from Ferrous Pseudomonas aeruginosa cd1 Nitrite Reductase: A NOVEL OUTLOOK ON THE CATALYTIC MECHANISM
43. Nitrite controls the release of nitric oxide in Pseudomonas aeruginosa cd 1 nitrite reductase
44. Importance of amino acids in brain parenchyma invasion by cancer cells
45. Studying GGDEF Domain in the Act: Minimize Conformational Frustration to Prevent Artefacts
46. Backbone dynamics and hydrogen exchange of Pseudomonas aeruginosa ferricytochrome c 551
47. Probing the activity of diguanylate cyclases and c-di-GMP phosphodiesterases in real-time by CD spectroscopy
48. Modelling of SHMT1 riboregulation predicts dynamic changes of serine and glycine levels across cellular compartments
49. Cytosolic localization and in vitro assembly of human de novo thymidylate synthesis complex
50. Targeting the Interaction between the SH3 Domain of Grb2 and Gab2
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