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Aim. The study aims to check whether individual side effects of treatment with TKIs in patients suffering from CML may contribute to the occurrence of anxiety symptoms. In addition, it was decided to check whether there were any relationships between age, gender, duration of treatment, and the intensity of anxiety, divided by the occurrence of individual side effects. Method. The study involved 91 patients and was conducted at the Hematology Clinic of the University Hospital in Krakow. The following questionnaires were used: created by the author, David Goldberg Questionnaire GHQ-28, and the four-dimensional 4DSQ Questionnaire. Results. The most frequently mentioned side effects of treatment were bone and joint pain, muscle cramps and pain, water retention, and fatigue. The mean duration of the disease was ten years. Our research showed that fatigue, nausea/indigestion, frequent infections, bone and joint pain, abdominal pain, and loss of appetite were the most common side effects of TKI treatment, which resulted in increased anxiety symptoms. Conclusions. The work of doctors, psychologists, and pharmaceutical companies on reducing/alleviating side effects may in the future affect a better quality of life for these patients. Early detection of severe anxiety and taking appropriate steps can prevent the emergence of more significant disorders. In addition, several years of attempts to discontinue treatment with some TKIs (imatinib and nilotinib) in patients who achieve a profound molecular response may improve their mental condition. [ABSTRACT FROM AUTHOR]

Aim. The paper presents the results of work on the Polish adaptation of the Self-Assessed Wisdom Scale (SAWS). It presents the psychometric properties of the Polish version of the tool. Method. The research was quantitative in nature and it was carried out in a correlation scheme. The respondents completed a set of questionnaires. 880 subjects aged 60-80 years (M = 68.15; SD = 5.96) participated in the study. Apart from the SAWS six other psychological methods were used. The selection of measuring tools was purposeful. Results. The final Polish version of the SAWS consists of 40 items (including 36 diagnostic ones) that make up 5 dimensions of wisdom: (1) "Critical Life Experience", (2) "Emotional Regulation", (3) "Reminiscence and Reflectiveness", (4) "Openness" and (5) "Humor". The reliability index for the entire scale (36 items) was a = 0.92 (very high). Reliability values (Cronbach's a) for individual scales vary from a = 0.60 to a = 0.84. The validity of the scale was evaluated by means of confirmatory analysis. Conclusions. The results are consistent with the original version of the scale, thus it has been indicated that the Polish version of the SAWS fulfils the psychometric requirements for psychological tests. The scale can be applied in scientific research. [ABSTRACT FROM AUTHOR]

Aim. Several studies have assessed the association between personality traits and metabolic outcomes in children and adolescents with type 1 diabetes (T1DM). The aim of this observational single-visit study was to investigate whether specific personality traits were related to the degree of metabolic control/diabetes duration in adult T1DM patients. Method. Data were collected from 56 adults (40 men) with T1DM treated in a tertiary care center. "Big Five" personality traits were assessed using the NEO-Five Factor Inventory questionnaire. Several variables were obtained from the insulin pumps, glucometers and blinded continuous glucose monitoring system. Results. All personality traits but neuroticism (low level of the trait) showed average intensity. Agreeableness was associated with most variables from CGMS data. Higher conscientiousness was associated with longer diabetes duration. Higher neuroticism was correlated with greater glycemic variability (GV), while high Extraversion was associated with lower GV. Lower Openness was associated with prolonged time in clinically significant hypoglycaemia Conclusions. Our study suggest that personality traits manifest in individual approach to diabetes management and emotion regulation, translating also into the attitude to treatment. On the other hand, T1DM patients' overall trait scores were consistent with healthy nonpsychiatric norms, which debunks myths and stereotypes suggesting that chronic disease is usually associated with psychopathology. [ABSTRACT FROM AUTHOR]

Aims: The aim of the study was to check the prevalence of unipolarity (depression), bipolarity, as well as the quality of sleep and temperament traits in patients with type 1 diabetes (T1DM) who are provided with optimal conditions of diabetes care and to identify possible risk factors connected with affective traits. Materials and Methods: Out of the 107 T1DM patients, 78 (54 females, 24 males) were included for the analysis (HbA1c [%] 7.11 ± 1.0, BMI [kg/m2] 25.3 ± 5.6; Years of disease duration [N] 13.7 ± 8.3). The patients filled in a set of questionnaires during their regular visit to the outpatient clinic. Three patients from the whole group were on intensive insulin therapy with Multiple Daily Injections (MDI) and Self‐Monitoring of Blood Glucose (SMBG), all the rest were on various types of personal insulin pumps (years on insulin pump [N] 9.1 ± 4.5). All the patients were on regular diabetologist care, with regular visits in a Centre for Advanced Technologies in Diabetes (at least every 6 months). Results: In QIDS‐S (full explanation and abbreviation 26 patients (33.8%) were screened positive for depression, in PHQ (full explanation and ab 57.7% of the patients (45 patients) had symptoms of depression (age was negatively correlated with PHQ score [r = −0.26; p = 0.023]). In CES‐D 16 (20%) of the patients assessed their present affect as depressed. None of the analysed clinical variables correlated with depression scores. In the Mood Disorder Questionnaire (MDQ), 16 patients reported having symptoms of bipolarity (20.5% vs. 79.5%). Hypomania Checklist (HCL) analysis indicated 10 patients with bipolar traits (>14) (14.9% vs. 85.1%). None of the analysed clinical variables correlated with HCL results. 11.5% of patients were indicated to be of morning type. Morningness was more often seen in younger patients (r = 0.39; p = 0.001). As many as 46.6% declared that they had poor sleep quality. The temperament traits analysis correlated with clinical parameters: Cyclothymic temperament trait was negatively correlated with age (r = −0.30; p = 0.007) and positively with HbA1c level (r = 0.30; p = 0.025). Hyperthymic temperament was positively correlated with (BMI r = 0.28; p = 0.016). Quality of sleep was highly correlated with depressive symptoms CESD (r = 0.61, p = 0.001), PHQ Score (r = 0.62; p = 0.001), QISD (r = 0.68; p = 0.001) and bipolarity MDQ (p = 0.50, p = 0.001) and HCL (r = 0.42, p = 0.001). In addition, QIDS was shown to be correlated with the following features of temperament: depressive factor (r = 0.41; p = 0.001), irritable factor (r = 0.53; p = 0.001), cyclothymic factor (r = 0.59; p = 0.001), anxious factor (r = 0.58, p = 0.001). Conclusions: The prevalence of affective disorders and poor sleep quality in the examined T1DM patients was much higher than in the general population. Even if the patients have in general good glycaemic control, their mental health condition should not be neglected. Well organised cooperation between patients, diabetologists, psychiatrists and psychotherapists is needed (Clinical Trials Identifier: NCT04616391). [ABSTRACT FROM AUTHOR]

Introduction: The aim of this study was to analyze the occurrence of depression, anxiety, and somatic symptoms in patients with chronic myeloproliferative neoplasms (essential thrombocythemia, polycythemia vera, and myelofibrosis) and to check whether individual side effects of interferon alpha treatment may contribute to the occurrence of depression, anxiety, and somatic symptoms. In addition, it was decided to check whether there were any relationships between age, gender, duration of treatment, and the intensity of anxiety, divided by the occurrence of individual side effects. Material and methods: The study involved 84 patients and was conducted at the Hematology Clinic of the University Hospital in Krakow, Poland and the Clinic of Hematology, Blood Cancer and Bone Marrow Transplantation in Wrocław, Poland. The following questionnaires were used: the David Goldberg Questionnaire GHQ-28, and the four-dimensional 4DSQ Questionnaire. Results: The most frequently reported side effects of treatment were abdominal pain, fatigue, and bone and joint pain. Almost 40% of the respondents obtained a moderately or strongly increased result on the depression scale, less than 50% on the anxiety scale, and over 60% on the somatization scale. Somatic symptoms had the greatest impact on the occurrence of mental disorders, with anxiety symptoms being second in significance. There are differences in the severity of depressive, anxiety, and somatic symptoms depending on the side effects of interferon alpha treatment. Conclusions: The findings of this study indicate the need for further research into the importance of detecting depressive, anxiety, and somatic disorders, and to addressing concomitant physical symptoms, both in patients with myeloproliferative neoplasms receiving interferon alpha and in those treated with other methods. In patients treated chronically, the occurrence of side effects of high intensity and lasting for a long time should alert medical personnel. The available data on patients with myeloproliferative neoplasms who have suffered from mental and physical symptoms of the disease or its treatment justifies the need for caring psychological, psychiatric, and educational care. [ABSTRACT FROM AUTHOR]

The article is a letter from the editors of the Archives of Psychiatry and Psychotherapy, addressing authors, reviewers, and readers. The editors mention that the June issue of the journal contains several interesting articles, including studies on physiological activity and personality traits in psychotherapy patients, the relationship between nature connectedness and mental health, a new measure for assessing anhedonia, the antidepressant effect of a compound called (-)- α- bisabolol, the links between inflammatory cytokines and schizophrenia, a case study on schizoid personality disorder, online and face-to-face therapy during the Covid-19 pandemic, and the prevalence of early maladaptive schemas in convicted sexual offenders. The editors hope that reading the journal will enrich readers' holiday time and inspire scientific exploration. [Extracted from the article]